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Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre et être actif -beaucoup- plus longtemps: Perspectives sociales, démographiques et de santé SPF Sécurité sociale, Bruxelles, 12 janvier 2015
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Page 1: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.

Increasing the length of healthy life: demographic and epidemiological

reflections

Jean-Marie RobineINSERM – EPHE, Paris and Montpellier, France

Vivre et être actif -beaucoup- plus longtemps:Perspectives sociales, démographiques et de santé

SPF Sécurité sociale, Bruxelles, 12 janvier 2015

Page 2: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.

The three theories of the 1980s

• The compression of morbidity: According to Fries, life expectancy was close to its maximum in the 1980s. Medical and health behaviors progress can only reduce the number of bad years to a small part of the life expectancy (Fries, 1980).

• The expansion of morbidity: On the opposite side, according to Gruenberg and Kramer, the same medical progress will increase the survival of frail elderly people such as those with dementia (Gruenberg, 1977; Kramer, 1980).

• The dynamic equilibrium: Between these two extreme futures, Manton proposed a dynamic equilibrium in which increased survival is offset by better control of chronic diseases, keeping the proportion of life lived in good health more or less constant (Manton, 1982).

Page 3: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.

The longevity revolution

• Worries about the future health status of the older population led the health authorities to build up population health surveillance systems in the 1980s including repeated cross sectional health surveys which allowed the functional health status of older people to be monitored.

• But no theory on health at that time was anticipating the longevity revolution which is currently occurring in most developed countries and which has led to impressive numbers of nonagenarians and centenarians.

Page 4: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.

The longevity revolution

Page 5: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.

Change in the number of centenarians in Europe vs. Japan

0

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Num

ber o

f cen

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(100

+)

Japan

Females Males Total

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Num

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Fourteen European countries

Male Female Total

Europe vs. Japan

Page 6: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.
Page 7: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.
Page 8: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.

Mechanism

Page 9: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.

Distribution des durées de vie individuellesen France depuis 1827 - pour 100.000 filles à la naissance

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0 10 20 30 40 50 60 70 80 90 100 110 120

Nom

bre

de d

écès

(dx

)

1827 1847 1867 1887 1907 1927 1947 1967 1987 2007

Change over time in the distribution of the ages at death in France since 1827, female - for 100.000 newborn

Page 10: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.

Distribution des durées de vie individuellesen France depuis 1827 - pour 100.000 filles à la naissance

0

1000

2000

3000

4000

5000

0 10 20 30 40 50 60 70 80 90 100 110 120

Nom

bre

de d

écès

(dx

)

1827 1847 1867 1887 1907 1927 1947 1967 1987 2007

Change over time in the distribution of the ages at death in France since 1827, female - for 100.000 newbornThe longevity revolution

Page 11: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.

Compression vs. shifting mortality

Page 12: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.

Bongaarts, 2005, 2009

Page 13: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.

Fries, 1980

Page 14: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.

How long are adult life durationsd(x) series

0

1 000

2 000

3 000

4 000

5 000

6 000

20 40 60 80 100 120

1876-80

1929-32

1988-93

Modal length of life (M)

Deviation above M

Maximum life span

Distribution of the ages at death in Switzerland1876-1880, 1929-1932, 1988-1993

Page 15: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.

Europe vs. Japan

Robine and Saito, 2009

Page 16: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.

Change in the number of centenarians in Europe vs. Japan

0

5000

10000

15000

20000

25000

30000

35000

40000

45000

1945

1950

1955

1960

1965

1970

1975

1980

1985

1990

1995

2000

2005

2010

Num

ber o

f cen

tena

rians

(100

+)

Japan

Females Males Total

0

5000

10000

15000

20000

25000

30000

35000

40000

45000

1945

1950

1955

1960

1965

1970

1975

1980

1985

1990

1995

2000

2005

2010

Num

ber o

f cen

tena

rians

(100

+)

Fourteen European countries

Male Female Total

Europe vs. Japan

Page 17: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.

Maximum life span in Japan (empirical observations)

Page 18: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.

Warning:Divergence and variability

Page 19: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.

Trends in life expectancy at age 65

Denmark, the United Statesand the Netherlands

Page 20: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.

Trends in life expectancy at age 65

Page 21: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.

Number of centenarians (100+)

Page 22: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.

Population ageing

Page 23: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.

Population ageing(i.e., % of the older people within the total population)

Page 24: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.

Population ageing

France Germany

(i.e., % of the older people within the total population)

Demographic dependancy ratio

Page 25: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.

The oldest old support ratio

Page 26: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.

World wide decline in the oldest old support ratio

As the number of people aged 50-74 for each person aged ≥ 85

Page 27: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.

Disability-free life expectancyFrance vs. Sweden

Page 28: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.

In France, women spend 42% of their years of life without disability (all disability levels conbined) versus 73% in Sweden

Disability-free life expectancy at age 65France vs. Sweden - in 2010 -

Page 29: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.

Trends in disability-free life expectancyat age 65

Page 30: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.

Compression of disability?

Page 31: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.

Dynamic equilibrium?

Page 32: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.

Expansion of disability?

Page 33: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.

Le cas des Pays Bas(Engelaer et al, in Robine et al, 2013)

Netherlands, 1985-2010

Sources: Engelaer et al, in Robine et al, 2013

Page 34: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.

Trends in prevalence of dementia

Page 35: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.

Decline in the prevalence of dementia

Larson et al, NEJM 2013

Page 36: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.

Thank you for your attention!

Page 37: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.

Increasing the length of healthy life: demographic and epidemiological

reflections

Jean-Marie RobineINSERM – EPHE, Paris and Montpellier, France

Vivre et être actif -beaucoup- plus longtemps:Perspectives sociales, démographiques et de santé

SPF Sécurité sociale, Bruxelles, 12 janvier 2015

Page 38: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.
Page 39: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.

Mortality and life expectancy above age 100

Page 40: Increasing the length of healthy life: demographic and epidemiological reflections Jean-Marie Robine INSERM – EPHE, Paris and Montpellier, France Vivre.

Number of oldest old in Franceby single age, 80 years and over

100

1000

10000

100000

1900 1910 1920 1930 1940 1950 1960 1970 1980 1990 2000 2010

Eff

ectif

s de p

opul

atio

n

80 81 82 83 84 85 86 87 88 89

90 91 92 93 94 95 96 97 98 99


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