19
Sample test questions INTEGRATED TEST EXAM “ Krok 1 ” Pharmacy ()
Sample test questions
INTEGRATED TEST EXAM
“Krok 1”
Pharmacy
()
Аналiтична хiмiя 2
1. What titrimetric method of analysisrequires the use of both external andinternal indicators?
A. NitritometryB. AlkalimetryC. Complexometric titrationD. PermanganatometryE. Argentometry
2. A solution contains calcium, barium,aluminium, potassium, and sodium cations.Into this solution a small amount ofammonium hydroxide and alizarin solutionwas added, which resulted in production ofred precipitate. What ion was detected asthe result of this reaction?
A. AluminiumB. CalciumC. BariumD. PotassiumE. Sodium
3. Select an indicator for argentometricdetermination of chloride ions using theMohr method:
A. Potassium chromateB. DiphenylcarbazoneC. EosinD. FluoresceinE. Methyl red
4. Quantitative determination of coppersalts by means of photometric titrationshould be conducted according to thecalibration graph that is built within thefollowing coordinates:
A. Optical density - concentrationB. Optical density - temperatureC. Optical density - liquid layer thicknessD. Light absorption intensity - wavelengthE. Optical density - wavelength
5. 2M solution of HCl was added intothe solution being studied, which resultedin formation of white precipitate thatturned black when processed with ammoniasolution. What cation is present in thissolution?
A. Hg2+2
B. Ag+
C. Pb2+
D. Ba2+
E. Mg2+
6. What should be measured duringquantitative determination of glucose bymeans of polarimetry?
A. Rotation angle of a polarized light beamB. Refractive indexC. Absorption coefficient of a polarized lightbeam in the solutionD. Light beam dispersion in the solutionE. Optical density of the solution
7. Concentration of ethyl alcohol in tincturesand some other dosage forms can bedetermined by means of refractometry.For this purpose the following should bemeasured:
A. Solution refractive indexB. Rotation angle of a light polarizationplaneC. Angle of total internal reflection of a lightbeamD. Light beam incidence angleE. Light beam refraction angle
8. Ammonium thiocyanate solution wasadded into the solution being studied.The resulting solution colored red. Thisanalytical effect indicates the presence ofthe following cation:
A. Iron(III)B. Mercury(II)C. SilverD. Mercury(I)E. Lead(II)
9. What reference electrode should beused for potentiometric determination in asolution that contains ammonia and sodiumhydroxide?
A. GlassB. PlatinumC. SilverD. Silver chlorideE. Zinc
10. When barium chloride solution wasadded into the solution being studied, itresulted in a white precipitate that was acid-and alkali-insoluble, which indicates thatthis solution contains:
A. Sulfate ionsB. Chloride ionsC. Nitrate ionsD. Permanganate ionsE. Iron(II) ions
11. What laboratory glassware is used intitrimetric methods of analysis to measureout a precise volume of a titrant?
A. BuretteB. PipetteC. Volumetric flaskD. Measuring cylinderE. Measuring glass
12. Quantitative content of oxalic
Аналiтична хiмiя 3
acid can be determined by means ofpermanganatometry. How to determine theequivalence point for this kind of titration?
A. When titrate changes its color afteranother drop of working solution is addedB. With redox indicator diphenylamineC. With pH indicatorD. With specific indicatorE. With adsorption indicator
13. Specify what method of redox titrationrequires the use of specific indicator - starch- to fix the end point:
A. IodometryB. PermanganatometryC. NitritometryD. CerimetryE. Bromatometry
14. To separate cations of the 6thanalytical group from cations of the 5thanalytical group (acid-base classification),the following is used:
A. Excess ammonia solutionB. Excess sodium hydroxide solutionC. Excess sulfuric acid solutionD. Acetic acid solutionE. Silver nitrate solution
15. To determine mass-volume fractionof ammonia in a solution, the followingsolution should be used:
A. Hydrochloric acidB. Sulfuric acidC. Potassium permanganateD. IodineE. Sodium hydroxide
16. Pharmacopoeia reaction to determinebenzoate ions requires interaction with thesolution of:
A. Iron(III) chlorideB. Potassium chlorideC. ResorcinD. Acetic anhydrideE. Diphenylamine
17. What reference electrode can be used
in potentiometric analysis of a medicinalsubstance?
A. Silver chlorideB. GlassC. QuinhydroneD. AntimonyE. Zinc
18. Why is there no group reagent for thecations of the 1st analytical group (acid-basecassification)?
A. Most of their salts are water-solubleB. They have close ionic radiiC. They have large ionic radiiD. They can form soluble basesE. They belong to biologically importantelements
19. What working solutions (titrants) areused in Volhard method (precipitationtitration)?
A. AgNO3 and NH4SCNB. H2SO4 and NaOHC. Na2S2O3 and K[I3]D. KMnO4 and KBrO3E. HClO4 and KOH
20. The third analitycal group of cations(acid-base classification) includes Ca2+,Sr2+, Ba2+. What acid can function as aprecipitator agent (group reagent) for thesecations?
A. H2SO4B. HNO3C. HCID. CH3COOHE. HCIO4
21. Reaction of sodium ions with potassiumhexahydroxoantimonate(V) in neutralmedium produces precipitate. Specify thecolor of this precipitate:
A. WhiteB. RedC. YellowD. GreenE. Blue
Органiчна хiмiя 4
1. Which compound of those listed belowis a condensed arene?
A.
B.
C.
D.
E.
2. Specify the Wurtz reaction among thosegiven below:
A.
B.
C.
D.
E.
3. Select the formula of diazonium salt:
A.
B.
C. C6H5 − N = OD. C6H5 − NH − C(O) − CH3E. (CH3)2N − N = O
4. Salts and esters of oxalic acid are called:
A. OxalatesB. AdipatesC. SuccinatesD. MalonatesE. Urates
5. What test is used for identification ofuric acid and other compounds with purinenucleus?
A. Murexide reactionB. Silver mirror reactionC. Lucas reagentD. Fehling reagentE. Copper mirror reaction
6. Select the compound with both pyrroleand pyridine nitrogen atoms from thosegiven below:
A. Theophylline
B. 2-Aminopyridine
C. Pteridine
D. Pyrimidine
E. Pyridazine
7. What reagent allows distinguishingbetween maltose (a reducing disaccharide)and sucrose (a non-reducing disaccharide)?
A. Tollens reagentB. NaOHC. FeCl3D. Br2E. K4[Fe(CN6)]
8. Specify the name of the alkene givenbelow according to the IUPAC substitutivenomenclature:
Органiчна хiмiя 5
CH3−CH−|
C2H5
CH=C−CH3
|CH3
A. 2,4-Dimethyl-2-hexeneB. 4-Ethyl-2-methyl-2-penteneC. 2-Ethyl-4-methyl-3-penteneD. 3,5-Dimethyl-4-hexeneE. 4-Ethyl-2-methyl-3-pentene
9. Cellulose hydrolysis produces thefollowing disaccharide:
A. CellobioseB. MaltoseC. SucroseD. GlucoseE. Lactose
10. Transformation C2H4 (alkene) −→C2H6 (alkane) occurs during the followingreaction:
A. HydrogenationB. DehydrogenationC. DehydrationD. HydrationE. Dimerization
11. What type of bonds participates increation of both linear and cyclic carboxylicacid associates in the form of dimers?
A. Hydrogen bondsB. Ionic bondsC. Polar covalent bondsD. Nonpolar covalent bondsE. Donor-acceptor bonds
12. The end-product of heating bromoethanewith aqueous solution of potassiumhydroxide is:
H3C − CH2 − Br + KOHH2O−−−→ ?
A. EthanolB. EthaneC. EtheneD. Ethanoic acidE. Diethyl ether
13. Name the product of starch hydrolysis:
A. GlucoseB. FructoseC. MannoseD. RiboseE. Galactose
14. What is the formula of salicylic acid?
A.
B.
C.
D.
E.
15. Which of the compounds given below isan aromatic one?
A.
B.
C.
D.
E.
16. Which of the listed monosaccharides is aketose?
Органiчна хiмiя 6
A. FructoseB. MannoseC. GlucoseD. GalactoseE. Ribose
17. Fructose is a monosaccharide, glucoseisomer. In medicine it is used in treatmentof hepatic disorders and as a part of specialdiets. Which formula corresponds with D-fructose?
A.
B.
C.
D.
E.
18. Dibazol (Bendazol) is a hypotensiveantispasmodic drug. Its mechanismof action is based on its ability toblock phosphodiesterase type 4 enzymeactivity. This drug contains the followingheterocyclic compound:
A. BenzimidazoleB. BenzeneC. ThiazoleD. PyridineE. Pyrimidine
19. Which formula corresponds with β-D-glucopyranose?
A.
B.
C.
D.
E.
20. What compound is synthesized by meansof beta-picoline oxidation?
A. Nicotinic acidB. Benzoic acidC. Uric acidD. Barbituric acidE. Ascorbic acid
21. What compound will be produced asthe result of toluene chlorination in thepresence of FeCl3 catalyst?
Органiчна хiмiя 7
A.
B.
C.
D.
E.
Фiзична та колоїдна хiмiя 8
1. What value determines the degreeof influence that foreign ions have on thepotential of an ion-selective electrode?
A. Selectivity coefficientB. Diffusion coefficientC. Activity coefficientD. Electrical conductivity coefficientE. Osmotic coefficient
2. Name the process of spontaneousadhesion of drops in an emulsion to eachother:
A. CoalescenceB. FlocculationC. SedimentationD. FlotationE. Coagulation
3. Enzymes are widely used as drugs inpharmacy. What is the main differencethat separates enzymes from non-biologicalcatalysts?
A. High specificity and selectivityB. High universalityC. Low universalityD. High dispersionE. High homogeneity
4. Name the structural unit of a colloidalsolution of a medicinal substance:
A. MicelleB. MoleculeC. AtomD. IonE. Zwitterion
5. Surfactants and high-molecularcompounds are added into concentratedemulsions to stabilize them. Thesesubstances are:
A. EmulsifiersB. ActivatorsC. CatalystsD. SolventsE. Absorbents
6. Specify the order of acetone breakdownreaction:
CH3COCH3 = C2H4 + H2 + CO
A. FirstB. SecondC. ThirdD. ZeroE. Fractional
7. What two methods of obtaining a dispersesystem can be characterized as physicalcondensation?
A. Vapour condensation and solventsubstitutionB. Chemical condensation and peptizationC. Dispergation and peptizationD. Ultrafiltration and peptizationE. Ultrafiltration and vapour condensation
8. If in the process of molecular adsorptionthe solute is being adsorbed more than thesolvent, then the following occurs:
A. Positive adsorptionB. Negative adsorptionC. No adsorptionD. Selective adsorptionE. Ion adsorption
9. What device is used to measure surfacetension of a liquid?
A. StalagmometerB. AreometerC. ViscometerD. CalorimeterE. Nephelometer
10. Sedimentation is characteristic of thefollowing systems:
A. SuspensionsB. Solutions of high-molecular compoundsC. Nonelectrolyte solutionsD. Electrolyte solutionsE. Foams
11. Under certain conditions, solutions ofhigh-molecular substances can lose theirflowability, meaning that the bonds beginto form between macromolecules, leadingto the formation of a spatial grid. Name thisprocess:
A. Gel formationB. CoacervationC. CondensationD. CoagulationE. Peptization
12. Collagen, gelatin, keratin, and myosinare the proteins that are formed withpeptide bonds and resemble long threadsin shape. Name this type of proteins:
A. Fibrillar proteinsB. Globular proteinsC. Chain proteinsD. Structured proteinsE. -
13. Name the ability of high-molecularcompounds to prevent precipitation oflyophobic sols and deposition of cholesterolplaques on the vessel walls:
Фiзична та колоїдна хiмiя 9
A. Colloid protectionB. CoacervationC. SedimentationD. CoagulationE. Thixotropy
14. Saline solution with 0.9% of NaCl inrelation to blood serum can be characterizedas:
A. IsotonicB. HypotonicC. HypertonicD. ColloidalE. -
15. Helmholtz energy is a direction criterionof a spontaneous process at a constant:
A. Temperature and volumeB. Temperature and pressureC. Entropy and volumeD. Internal energy and volumeE. Entropy and pressure
16. Name the process of removing one orseveral substances from a complex systemby means of a selective solvent:
A. ExtractionB. EvaporationC. CrystallizationD. DispersionE. Condensation
17. In medical and pharmaceutical practicethe phenomena of adsorption, wetting, andadhesion are regularly observed. Name thisgroup of phenomena:
A. Surface phenomenaB. Electrokinetic phenomenaC. Molecular-kinetic phenomenaD. Optical phenomenaE. Physico-chemical phenomena
Патологiчна фiзiологiя 10
1. I.I.Mechnikov, when studyinginflammatory process, described a certainorder that is characteristic of leukocytemigration to the inflammation focus. Thecells emigrate to the focus in the followingorder:
A. Neutrophilic granulocytes, monocytes,lymphocytesB. Monocytes, lymphocytes, neutrophilicgranulocytesC. Neutrophilic granulocytes, lymphocytes,monocytesD. Monocytes, neutrophilic granulocytes,lymphocytesE. Lymphocytes, monocytes, neutrophilicgranulocytes
2. A patient has developed anuria. Bloodpressure is 50/20 mm Hg. What processof uropoiesis caused acute decrease ofurination?
A. Glomerular filtrationB. Obligatory reabsorptionC. Facultative reabsorptionD. Tubular secretionE. -
3. During lancing an abscess in theoral cavity, it produces a yellow-greendischarge. What cells are always present andpredominant in the purulent exudate?
A. NeutrophilsB. EosinophilsC. BasophilsD. LymphocytesE. Erythrocytes
4. People, who were in the building during afire, suffer from carbon monoxide poisoning.What type of hypoxia can be observed in thiscase?
A. HemicB. CirculatoryC. HypoxicD. RespiratoryE. Tissue
5. A 42-year-old patient presents withskin pallor, weakness, and enlarged lymphnodes. In peripheral blood: leukocytosis,no intermediate forms of leukocytes(”leukemic hiatus”), accelerated ESR. Whatdisease can be suspected in this case?
A. Acute leukemiaB. Chronic leukemiaC. ErythromyelosisD. Neutrophilic leukocytosisE. Leukemoid reaction
6. To reproduce Ehrlich carcinoma in arabbit, a certain amount of benzpyrene (a
polycyclic aromatic hydrocarbon) was dailyapplied to a dehaired patch of skin of theanimal. What method is used for tumormodelling in this case?
A. InductionB. TransplantationC. ExplantationD. Ionizing radiationE. Hormone administration
7. After a surgery the patient presented witha severe pain syndrome. What change in thepatient’s hormonal status is most likely inthis case?
A. Increased catecholamine productionB. Insulin hypersecretionC. Decreased ACTH productionD. Decreased production of glucocorticoidsE. Decreased production ofmineralocorticoids
8. A 9-year-old child due to acute bronchitisdeveloped elevated body temperature up to38.5oC that lasted for a week and was thenfollowed by a drop in the temperature downto 37.0oC. What mechanism is leading at the3rd stage of fever?
A. Peripheral vasodilationB. Increased heat productionC. Development of chillsD. Increased diuresisE. Increased respiration rate
9. One hour after a child took polyvitaminsin the dosage form of a syrup, the childdeveloped a markedly itching urticaria-typerash all over the body. What type of allergicresponse can be characterized by this sign?
A. AnaphylacticB. Immune complexC. CytotoxicD. Delayed-type hypersensitivityE. Autoallergic
10. A patient develops prolongedhemorrhages and hemorrhages into themuscles and joints as a result of anymicrotraumas. In the blood there is adeficiency of the VIII plasma factor of bloodcoagulation. What disease of blood systemis observed in this patient?
A. Hemophilia AB. B12 and folate deficiency anemiaC. Iron-deficiency anemiaD. Thrombocytopenic purpuraE. Vaquez disease (polycythemia vera)
11. A man received a radiation dose of30 Gy. He presents with necrotic angina,disorders of the gastrointestinal tract. Bloodtests revealed anemia, leukopenia and
Патологiчна фiзiологiя 11
thrombocytopenia. What stage of acuteradiation sickness is observed in the patient?
A. Manifest illness stageB. Prodromal stageC. Latent stageD. RecoveryE. -
12. A 54-year-old man requested apharmacist’s advice on drug prescription.The patient has 4-year-long history ofchronic glomerulonephritis and 2-year-longhistory of persistent hypertension. Whatsubstance synthesized in the kidneys hasimportant role in development of arterialhypertension?
A. ReninB. Nitric oxideC. AldosteroneD. HistamineE. Catecholamines
13. Examination of a 45-year-old man, whofor a long time kept to a vegetarian plant-based diet, revealed him to have negativenitrogen balance. What peculiarity of hisdiet has caused such developments?
A. Insufficient protein contentB. Insufficient fat contentC. Insufficient vitamin contentD. Excessive water contentE. Excessive carbohydrate content
14. A 23-year-old man came to the infectiousdiseases department with complaints ofabdominal distension and diarrhea. He wasdiagnosed with lambliasis. What type ofleukocytosis is characteristic of this disease?
A. EosinophilicB. NeutrophilicC. BasophilicD. LymphocyticE. Monocytic
15. What is the mechanism of indirect actionof ionizing radiation on cells?
A. Formation of large amount of free radicalsB. Chromosome ruptureC. Damage to the cytoplasmic membraneD. Swelling of organellesE. Activation of protein biosynthesis
16. A couple came to the geneticconsultation for their newborn child tobe examined. Karyotype test detects anadditional chromosome in the 21 pair. Whatdiagnosis can be made?
A. Down syndromeB. Edwards syndromeC. Patau syndromeD. Turner syndromeE. Klinefelter syndrome
17. After a physical exertion a persondevelops extra (premature) cardiaccontractions. What type of arrhythmia is it?
A. ExtrasystoleB. Sinus tachycardiaC. Sinus bradycardiaD. Ventricular fibrillationE. Paroxysmal tachycardia
18. A 55-year-old man came to a doctorwith complaints of acute pain in his big toes.Meat and wine are always present in his diet.The doctor suspects gout. What substancemust be measured in the patient’s blood toconfirm this diagnosis?
A. Uric acidB. UreaC. LactateD. BilirubinE. Ketone bodies
Бiологiчна хiмiя 12
1. A patient suffers from diarrhea,dermatitis, and dementia. What vitamin islikely to be deficient in this patient, causingthe patient’s condition?
A. Nicotinic acidB. Vitamin KC. Vitamin DD. TocopherolE. Retinol
2. An unconscious patient was brought intothe intensive care unit. Acetone breath,acute hyperglycemia, and ketonemia aredetected. What complication of diabetesmellitus occurred in this case?
A. Diabetic comaB. Hypoglycemic comaC. CataractD. Acute acetone poisoningE. Nephritis
3. Serum total protein is one of metabolicindicators. What reaction is usually used inclinical laboratories to measure this value?
A. BiuretB. NinhydrinC. XanthoproteicD. FohlE. Nitroprusside
4. Thyroid gland produces a hormonethat regulates Ca2+ levels in blood, whichfacilitates mineralization of bone tissue.What hormone has such an effect?
A. ThyrocalcitoninB. ThyroxinC. TriiodothyronineD. DopamineE. Adrenaline
5. A patient is diagnosed with acutepancreatitis. For diagnostic purpose it isnecessary to measure the activity of thefollowing enzyme in the patient’s blood:
A. AmylaseB. AldolaseC. LDHD. Creatine kinaseE. Pepsin
6. What enzyme allows for synthesis ofvarious genes from template-RNA toDNA in genetic engineering (this enzymecatalyzes the process discovered in RNA-viruses)?
A. Reverse transcriptaseB. ExonucleaseC. DNA-ligaseD. HelicaseE. Endonuclease
7. Primary structure of nucleic acids is apolynucleotide chain that has a certaincomposition and order of the nucleotides.What bonds stabilize this structure?
A. 3′, 5′-phosphodiesterB. PeptideC. GlycosidicD. DisulfideE. Amide
8. Gout develops when purine nucleotidemetabolism is disturbed. A doctorprescribed the patient allopurinol that is acompetitive inhibitor of:
A. Xanthine oxidaseB. Succinate dehydrogenaseC. Alcohol dehydrogenaseD. Lactate dehydrogenaseE. Hexokinase
9. Cocarboxylase is used in medicine as apharmaceutical preparation for treatmentof myocardial dystrophy and conditions thataffect muscles and peripheral CNS. Whatvitamin is a component of this preparation?
A. B1B. B2C. B6D. CE. B12
10. A patient complains of polyuria. Urinetest detects no pathologic components, buturine specific gravity is abnormally low.What hormone secretion is likely to bedisturbed in this patient?
A. VasopressinB. SomatotropinC. ThyrotropinD. InsulinE. Cortisol
11. A patient with hyperproduction ofthyroid hormones has been prescribedMerkazolilum. This drug inhibits thefollowing enzyme participating iniodothyronine synthesis:
A. Iodide peroxidaseB. AromataseC. ReductaseD. DecarboxylaseE. Aminotransferase
12. Ascorutin vitamin preparation is usedfor treatment of bleeding gums and punctatehemorrhages. What vitamin does thispreparation contain?
Бiологiчна хiмiя 13
A. CB. KC. DD. AE. E
13. A man developed high plasma iron levelsdue to intensified hemolysis of erythrocytes.What plasma protein transports iron?
A. TransferrinB. InterferonC. CeruloplasminD. AlbuminE. Histone
14. In case of hypovitaminosis of a certainvitamin, disturbed proliferation of epithelialand connective tissue can be observed.Patients with this type of hypovitaminosisusually present with impaired vision andspatial orientation. Name this vitamin:
A. RetinolB. CholecalciferolC. TocopherolD. RiboflavinE. Pyridoxine
15. Antihistamines are used in treatmentof allergic responses, because histaminefunctions as an allergic response mediator.Name the amino acid from which histamineis produced:
A. HistidineB. GlycineC. AsparagineD. TyrosineE. Alanine
16. Cholesterol synthesis inhibitors are usedas antiatherosclerotic drugs. Select one suchdrug from the list:
A. LovastatinB. SulfanilamideC. BenzylpenicillinD. PancreatinE. Chloramphenicol
17. Aspartame is used as a sweetener and intreatment of diabetes mellitus. What aminoacid does it contain?
A. Aspartic acidB. Glutamic acidC. ValineD. LeucineE. Methionine
18. Hemoglobin break-up begins in thecells of reticuloendothelial system. Whatenzyme catalyzes the reduction reaction ofbiliverdine into bilirubin?
A. Biliverdine reductaseB. Beta-glucuronidaseC. Xanthine oxidaseD. Heme oxygenaseE. Hexokinase
Фармацевтична ботанiка 14
1. Plants that grow in moderatelyhumid conditions belong to the followingecological group:
A. MesophytesB. HydrophytesC. HygrophytesD. XerophytesE. Succulents
2. Among the trees of Fabaceae family thereis an early-flowering melliferous plant withpinnately compound leaves, spine-shapedstipules, and white fragrant flowers arrangedin hanging racemes. Name this plant:
A. Robinia pseudoacaciaB. Armeniaca vulgarisC. Aesculus hippocastanumD. Aronia melanocarpaE. Quercus robur
3. Select a Brassicaceae family plant thatcontains glycosides similar in action to thoseobtained from foxglove:
A. Erysimum canescensB. Arctostaphylos uva-ursiC. Urtica dioicaD. Polygonum aviculareE. Primula officinalis
4. Among harvested plants there wasCapsella bursa-pastoris, which can becharacterized as follows:
A. Annual plant, basal leaves - pinnatisectedor pinnatipartite, fruit - small triangularheart-shaped siliqueB. Biennial plant, basal leaves - pinnatilobate,fruit - small round siliqueC. Perennial plant, basal leaves - entire-kind,fruit - cylindric siliqueD. Annual plant, basal leaves - compound,fruit - segmented siliqueE. Biennial plant, basal leaves - membranous,fruit - small winged heart-shaped silique
5. Berberis vulgaris has spines that aremodifications of:
A. LeavesB. StipulesC. PetiolesD. StemsE. Rachises
6. In monocotyledonous plants metabolismend-products are often represented bymultiple needle crystals of calcium oxalatearranged in clusters. Name these structures:
A. RaphidesB. DrusesC. StyloidsD. Twinned crystalsE. Crystalline sand
7. Name the male gametophyte of floweringplants:
A. Pollen grainsB. CarpelC. Embryo sacD. OvuleE. Nucellus
8. A gastric tea contains small oval brownlignified cone-shaped plant parts up to 1.5cm in length that can be identified as:
A. Aggregate fruits of alnusB. Larch conesC. Cypress conesD. Berry-like juniper conesE. Platycladus orientalis cones
9. A diagnostic feature important forcorrect identification of pine species is thenumber of needles on the short shoots(brachyblasts). Pinus sylvestris has thefollowing number of needles on its shortshoots:
A. 2B. 5C. 3D. 8E. Many
10. In pharmaceutical manufacturing, rutinand quercetin are obtained from the flowersof a certain Fabaceae family plant. Namethis plant:
A. Styphnolobium japonicumB. Robinia pseudoacaciaC. Caragana arborescensD. Astragalus piletocladusE. Acacia dealbata
11. A cough tea contains comminuted rootsof a plant. The roots are colored brightyellow and taste sweet. They were identifiedas roots of the following plant:
A. Glycyrrhiza glabraB. Althaea officinalisC. Acorus calamusD. Valeriana officinalisE. Sanguisorba officinalis
12. Nuciform fruits include a certain type ofone-seeded fruit that does not burst whenripe. Its base is enclosed in a cup-shapedcupule formed by the broad part of thepeduncle to which the flower was attached.Name this type of fruit:
Фармацевтична ботанiка 15
A. AcornB. NutC. NutletD. SamaraE. Caryopsis
13. Plantago major inflorescence grows atthe apex, its rachis is long, with sessileflowers. Name this type of inflorescence:
A. SpikeB. PanicleC. SpadixD. CapitulumE. Thyrse
14. Upon examination of a flower it isdetermined to have one pistil made up ofsingle free carpel. Therefore, this gynoeciumcan be identified as:
A. MonocarpousB. ApocarpousC. LysicarpousD. ParacarpousE. Syncarpous
15. One of the important diagnostic featuresof garden sage and motherwort is theirshape of corolla. Their flowers have thefollowing type of corolla:
A. BilabiateB. Thimble-shapedC. FunnelformD. PseudoligulateE. Ligulate
16. Rhizome of an Asteraceae familyspecies is polycephalous, succulent, haslysigenous cavities, accumulates inulin. Suchunderground organ is characterisic of:
A. Inula heleniumB. Hyoscyamus nigerC. Digitalis grandifloraD. Sorbus aucupariaE. Helianthus annuus
Мiкробiологiя 16
1. To obtain bacterial exotoxins,microorganisms are cultivated in a liquidnutrient medum, into which the toxinsare being discharged. What method allowsclearing the medium of microorganisms, sothat only pure exotoxins will remain in themedium?
A. Filtration through bacterial filtersB. BoilingC. AutoclavingD. Ultraviolet irradiationE. Application of disinfectants (Chloramine)
2. In the course of bacteriologicalexamination of the feces of a patient withdiarrhea, a pure culture of slightly curvedbacilli was obtained. In the microslide thesemicroorganisms were arranged in clustersresembling schools of fish. Cultivation in thealkaline medium (alkaline peptone water)in six hours resulted in formation of a blue-tinged film. These features are characteristicof the following causative agent:
A. Vibrio choleraeB. ColibacilliC. SalmonellaeD. SpirochetesE. Mycobacteria
3. One day after eating meatballs in theschool canteen, several students came to thenurse’s office complaining of stomachache,vomiting, high body temperature, anddiarrhea. One of the students washospitalized in a severe condition. Whatmicroorganisms can be the cause of this foodtoxicoinfection?
A. SalmonellaeB. StreptococciC. ClostridiaeD. ShigellaeE. Meningococci
4. For tetanus prevention a certain toxinis used. For 4 weeks this toxin is beingneutralized with formaldehyde (0.4%)under the temperature of 39oC. Name theresulting preparation:
A. AnatoxinB. ImmunoglobulinC. Antitoxic serumD. AdjuvantE. Inactivated vaccine
5. After examination the patient wasdiagnosed with tick-borne encephalitis.What route of transmission is characteristicof this disease?
A. Vector-borne transmissionB. Vertical transmissionC. Airborne droplet transmissionD. Fecal-oral transmissionE. Parenteral transmission
6. A chemotherapeutic agent hasbactericidal effect against streptococci,staphylococci, bacilli, and clostridia.According to its action spectrum this drugbelongs to the following group:
A. Broad spectrum antibacterial agentsB. Narrow spectrum antibacterial agentsC. Broad spectrum antifungal agentsD. Antiviral agentsE. Antituberculous agents
7. It is known, that HIV infection leadsto severe immunologic disturbances inthe body that result in the developmentof AIDS (acquired immune deficiencysyndrome). What cells of the human bodyare the most susceptible to HIV infection?
A. T helper cellsB. HepatocytesC. Suppressor T cellsD. EndotheliocytesE. B lymphocytes
8. Microbe survival within environment isfacilitated by spore formation. What genusof microorganisms can be characterized asspore formers:
A. ClostridiumB. BacteroidesC. StaphylococcusD. PeptococcusE. Peptostreptococcus
9. To induce an artificially acquired activeimmunity, a three-month-old child was givenorally a Sabin strain-based live culturalvaccine. This vaccine is used for preventionof:
A. PoliomyelitisB. TuberculosisC. MeaslesD. RubellaE. Parotitis
10. After examination the child wasdiagnosed with scarlet fever. Whatmicroorganism is a causative agent of thisdisease?
A. StreptococcusB. StaphylococcusC. MeningococcusD. KlebsiellaE. Actinomycete
11. A ready-made drug was inoculated onSabouraud’s agar and incubated under 22oC
Мiкробiологiя 17
for 5 days. This nutrient medium was usedto determine the following:
A. Number of mold and yeast fungiB. Total number of bacteriaC. Presence of E. coliD. Presence of S. aureusE. Presence of Salmonella
12. Seitz filters are widely used in laboratorypractice. What is their purpose?
A. Sterilization by means of filtrationB. Disinfection of solutionsC. Measurement of water contaminationD. Growing of bacteriophagesE. Virus destruction
13. Thermolabile medicinal preparationfor extemporal use was heated to 65oCthrice with intervals of one day between theheatings. What method of sterilization wasused in this case?
A. TyndallizationB. PasteurizationC. Koch’s steam sterilizationD. CalcinationE. Filtration
14. Many serological reactions requirestrictly aseptic conditions. What method ofsterilization is optimal for decontaminationof laboratory glassware?
A. Dry heatB. TyndallizationC. PasteurizationD. FiltrationE. Calcination
15. During microscopy of a smearmade from the sputum sample andstained according to the Ziehl-Neelsentechnique, the medical laboratory scientistdetected bright red acid-fast bacilli
arranged separately and in groups. Whatmicroorganisms were detected?
A. Micobacterium tuberculosisB. Bacillus anthracisC. Salmonella typhiD. Staphylococcus aureusE. Bordetella pertussis
16. Sanitary-microbiological assessment ofwater quality in the water supply systemconducted by the sanitary-epidemiologicalstation detected microorganisms indicativeof fecal contamination of water. Whatmicroorganisms were detected?
A. Escherichia coliB. Streptococcus agalactiaeC. Haemophilus influenzaeD. Neisseria siccaE. Staphylococcus aureus
17. Air contamination with pathologicalmicroorganisms can be anticipated by thepresence of indicator bacteria. Specifythe bacteria that indicate immediateepidemiologic danger:
A. Hemolytic streptococciB. SarcinaeC. Mold fungiD. Yeast fungiE. Micrococci
18. It can be safely assumed that the infantsborn from the mothers with the history ofmeasles will not be affected by the measlesoutbreak during their stay in the maternityward. What classes of antibodies provide theinfants with the resistance to this disease?
A. IgGB. IgAC. IgDD. IgME. IgE
Фармакологiя 18
1. During a surgery, tubocurarin chloridewas used as a muscle relaxant. Whatantagonist should the patient be given torestore spontaneous breathing?
A. Proserin (Neostigmine)B. Dithylin (Suxamethonium)C. Cytitone (Cytisine)D. Aethimizole (Methylamide)E. Benzohexonium (Hexamethonium)
2. A patient, who has been takingphenazepam for a month, came to thepharmacy. He insists that he needs to buytwo more packages of this drug, becausewithout it he feels unwell. The side-effect ofthis drug that can be observed in this patientis based on the development of:
A. AddictionB. IdiosyncrasyC. After-effectD. CumulationE. Tolerance
3. Select the halogenated antiseptic thatwould be preferable for a child to pack inthe first aid kit, when going to a summercamp:
A. Iodine alcoholic solutionB. Brilliant greenC. Copper sulfateD. Methylene blueE. Formaldehyde solution
4. A medical student needs to choosean adrenergic drug for treatment ofanaphylactic shock. What would yourecommend?
A. Adrenaline hydrochlorideB. Clophelin (Clonidine)C. Galazolin (Xylometazoline)D. FenoterolE. Izadrin (Isoprenaline)
5. What is the main mechanism ofbenzylpenicillin bactericidal action on thecoccal flora?
A. Disturbed synthesis of microbial cell wallB. Inhibition of protein synthesisC. Disturbed cytoplasmic membranepermeabilityD. Activation of macroorganism immunesystemE. Increased phagocytic activity of leukocytes
6. What drug can quickly stop an anginapectoris attack, when taken sublingually?
A. NitroglycerineB. DigoxinC. AmiodaroneD. LisinoprilE. Corglycon
7. Name the ability of a drug to accumulatewithin the patient’s body:
A. CumulationB. AntagonismC. SynergismD. HabituationE. Allergy
8. You work in the pharmacy located at thepremises of the dermatovenerologic clinic.Consult an intern what antibiotic is a drugof choice for treatment of syphilis:
A. Benzylpenicillin sodium saltB. Lincomycin hydrochlorideC. Levorin sodium saltD. Streptomycin sulfateE. Polymyxin M sulfate
9. A doctor has prescribed a nonsteroidalanti-inflammatory drug to relieveinflammation and pain syndrome. Name thisdrug:
A. Diclofenac sodiumB. GlibenclamideC. LoratadineD. PrednisoloneE. Calcium chloride
10. What is the most common side-effect ofinhaled corticosteroids?
A. Oropharyngeal candidiasisB. Increased body massC. OsteoporosisD. Subcapsular cataractE. Arterial hypertension
11. Treatment with sodium bromideresulted in development of bromism in thepatient: rhinitis, cough, conjunctivitis, andskin rashes. What should the patient beprescribed to treat this condition?
A. Sodium chlorideB. Potassium chlorideC. Sodium iodideD. Calcium chlorideE. Sodium sulfate
12. A patient with allergic rhinitis wasprescribed loratadine. This drug belongs tothe following group of antiallergic agents:
A. H1-antagonistsB. H2-antagonistsC. GlucocorticoidsD. Membrane stabilizersE. Leukotriene receptor antagonists
Фармакологiя 19
13. A patient suffers from intense coughwith production of viscous sputum. Whatdrug can thin the sputum and facilitateexpectoration?
A. AcetylcysteineB. PrenoxdiazineC. Codeine phosphateD. GlaucineE. Butamirate
14. A patient with myocardial infarction wasreceiving heparin as a part of the complextherapy. With time the patient developedhematuria. What drug should be given as anantidote in this case?
A. Protamine sulfateB. Aminocaproic acidC. Vicasol (Menadione)D. FibrinogenE. Neodicumarin
15. A patient with tracheitis was prescribeda centrally acting antitussive drug that doesnot depress respiration, causes no addiction,and lowers blood pressure. Name this drug:
A. Glaucine hydrochlorideB. Codeine phosphateC. Morphine hydrochlorideD. AcetylcysteineE. Prenoxdiazine
16. What drug is used for treatment oforganophosphate poisoning?
A. Atropine sulfateB. AciclovirC. PlatyphyllineD. MetronidazoleE. Izoniazid
17. Select the drug with anti-herpesvirusactivity that can be used for prevention andtreatment of herpetic lesions on skin andmucosa:
A. AciclovirB. NystatinC. AtropineD. RanitidineE. Rifampicin
18. Forced diuresis needs to be induced ina patient with acute medication poisoning.What drug must be used for this purpose?
A. FurosemideB. StrophantinC. ProgesteroneD. BisacodilE. Diphenhydramine
19. Caffeine is one of the alkaloids containedin tea and coffee. Caffeine is contraindicatedin case of:
A. Essential hypertensionB. FatigueC. HypotensionD. Depression of nervous activityE. Migraine
20. To quickly relieve the state of acutepsychosis, the patient was prescribed arapid/short-acting psychotropic drug. Namethis drug:
A. DroperidolB. Valerian extractC. PiracetamD. AmitriptylineE. Caffeine and sodium benzoate
21. After ishemic stroke the patient wasprescribed a drug to improve his intellectualfunctioning and memory. What drug shouldhe obtain from the pharmacy?
A. PiracetamB. MetoclopramideC. Tabex (Cytisine)D. Diphenin (Phenytoin)E. -
