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Interhospital Echo conference Thida Yingchutrakul. M.D.
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Page 1: Interhospital Echo conference - Thai  · PDF fileInterhospital Echo conference Thida Yingchutrakul. M.D. History ... Robert H. Anderson.

Interhospital Echo conference

Thida Yingchutrakul. M.D.

Page 2: Interhospital Echo conference - Thai  · PDF fileInterhospital Echo conference Thida Yingchutrakul. M.D. History ... Robert H. Anderson.

History

An 80-year-old Thai female

CC : progressive dyspnea for 1 month

PI : 3 months ago: She reported of dyspnea on

exertion and orthopnea but denied palpitation or

chest pain. She was admitted to private hospital

and diagnosed CHF. Her symptoms were slightly

improved after treatment.

Page 3: Interhospital Echo conference - Thai  · PDF fileInterhospital Echo conference Thida Yingchutrakul. M.D. History ... Robert H. Anderson.

PI : 1 month later, She became worsening

dyspnea with generalized edema. She was

admitted at a private hospital for a few days and

referred to King Chulalongkorn Memorial Hospital.

History

Page 4: Interhospital Echo conference - Thai  · PDF fileInterhospital Echo conference Thida Yingchutrakul. M.D. History ... Robert H. Anderson.

10 years PTA: Hypertension and dyslipidemia

1 months PTA: Hyperthyroidism

Current Medication:

1. Warfarin 2.5 mg/day

2. Digoxin 0.125 mg/day

3. Aspirin 81 mg/day

4. Bisoprolol 10 mg/day

5. Valsartan 160 mg/day

Past History

6. Furosemide 20 mg/day

7. Trimetazidime 70 mg/day

8. Isosorbide mononitrate

20 mg/day

9. PTU 100 mg/day

10. Addi-K 750 mg/day

Page 5: Interhospital Echo conference - Thai  · PDF fileInterhospital Echo conference Thida Yingchutrakul. M.D. History ... Robert H. Anderson.

Physical examination An elderly Thai female, good consciousness, looked

chronically ill, no respiratory distress

• Vital signs:

BP 140/70 mmHg, PR 80 bpm (regular), RR 18/min

• HEENT : mild pale conjunctivae, anicteric sclerae

JVP 3 cm above sternal angle

• Heart : Apical impulse at left 5th ICS, MCL, no heave/thrill

normal S1, S2

Continuous murmur gr. III/VI at LUPSB

Pan systolic murmur gr. II/VI at apex radiate to axiila

• Lungs : no crepitation, no wheezing

• Extremities : no pitting edema

Page 6: Interhospital Echo conference - Thai  · PDF fileInterhospital Echo conference Thida Yingchutrakul. M.D. History ... Robert H. Anderson.

CXR

Page 7: Interhospital Echo conference - Thai  · PDF fileInterhospital Echo conference Thida Yingchutrakul. M.D. History ... Robert H. Anderson.

EKG

Page 8: Interhospital Echo conference - Thai  · PDF fileInterhospital Echo conference Thida Yingchutrakul. M.D. History ... Robert H. Anderson.
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*

Page 32: Interhospital Echo conference - Thai  · PDF fileInterhospital Echo conference Thida Yingchutrakul. M.D. History ... Robert H. Anderson.

*

Page 33: Interhospital Echo conference - Thai  · PDF fileInterhospital Echo conference Thida Yingchutrakul. M.D. History ... Robert H. Anderson.
Page 34: Interhospital Echo conference - Thai  · PDF fileInterhospital Echo conference Thida Yingchutrakul. M.D. History ... Robert H. Anderson.

Stress CMR

Negative stress inducible ischemia

No myocardial hyper-enhancement

Page 35: Interhospital Echo conference - Thai  · PDF fileInterhospital Echo conference Thida Yingchutrakul. M.D. History ... Robert H. Anderson.

ALCAPA or Bland White Garlan syndrome

Page 36: Interhospital Echo conference - Thai  · PDF fileInterhospital Echo conference Thida Yingchutrakul. M.D. History ... Robert H. Anderson.

Anomalous of Left Coronary Artery from Pulmonary Artery

Page 37: Interhospital Echo conference - Thai  · PDF fileInterhospital Echo conference Thida Yingchutrakul. M.D. History ... Robert H. Anderson.

Incidence

• 1/250 – 1/400 of all congenital malformed hearts

• Overall incidence : 1/300,000 children • Frequency in boys (2.3 : 1)

Paediatric Cardiology, 3rd edition: Robert H. Anderson.

Page 38: Interhospital Echo conference - Thai  · PDF fileInterhospital Echo conference Thida Yingchutrakul. M.D. History ... Robert H. Anderson.

Pathophysiology

• Fetus : diastolic PAP = systemic pressure : coronary a. perfusion same as in normal • After birth

: PAP -> coronary steal : LV ischemia : develop collateral connection from RCA

http://nursingcrib.com/nursing-notes-reviewer/fetal-circulation/ Paediatric Cardiology, 3rd edition: Robert H. Anderson.

Page 39: Interhospital Echo conference - Thai  · PDF fileInterhospital Echo conference Thida Yingchutrakul. M.D. History ... Robert H. Anderson.

• Typically : RCA enlarge at its origin : LCA turn to be small, relative thin-walled : collateral may be diffusely large, well distributed

Pathophysiology

Paediatric Cardiology, 3rd edition: Robert H. Anderson.

Page 40: Interhospital Echo conference - Thai  · PDF fileInterhospital Echo conference Thida Yingchutrakul. M.D. History ... Robert H. Anderson.

Presentation

• Majority present during infancy • Myocardial ischemia -> CHF • Anginal attack -> severe distress, grunting, or crying • Unexplained heart murmur • Myocardial ischemia in children/ young adult • May be sudden unexplained death • Progressive MR (fibrosis involve pappillary m, LV dilatation)

Paediatric Cardiology, 3rd edition: Robert H. Anderson.

Page 41: Interhospital Echo conference - Thai  · PDF fileInterhospital Echo conference Thida Yingchutrakul. M.D. History ... Robert H. Anderson.

Clinical course and prognosis

• 10%–15% of patients survive to adulthood (extensive intercoronary collaterals)

• extent of collateral vascularisation -> clinical course • may present later in childhood, adolescence, or adulthood with

progressive MR, CHF, or myocardial ischaemia with exertion • Untreated -> prognosis is poor

Asian Cardiovasc Thorac Ann 2006;14:38-42

Page 42: Interhospital Echo conference - Thai  · PDF fileInterhospital Echo conference Thida Yingchutrakul. M.D. History ... Robert H. Anderson.

Echocardiography : Vol 24, Issue 4 ,28-2-2007

Page 43: Interhospital Echo conference - Thai  · PDF fileInterhospital Echo conference Thida Yingchutrakul. M.D. History ... Robert H. Anderson.

J Chin Med Assoc , September 2010: Vol 73, No 9

Page 44: Interhospital Echo conference - Thai  · PDF fileInterhospital Echo conference Thida Yingchutrakul. M.D. History ... Robert H. Anderson.

MRI

• Described coronary a. anatomy and origin of LCA from PA • Assess venticular function and volume • Identify MR (secondary to ischemia) • RWMA/ myocardial ischemia • Retrograde/ bidirectional flow in proximal LCA • Post-repaired -> supravalve PS at site of PA patch

Cardiovascular MRI in Congenital Heart Diseas: Shankar Sriharan

Page 45: Interhospital Echo conference - Thai  · PDF fileInterhospital Echo conference Thida Yingchutrakul. M.D. History ... Robert H. Anderson.

CLINICS 2010;65(11):1215-1216

Page 46: Interhospital Echo conference - Thai  · PDF fileInterhospital Echo conference Thida Yingchutrakul. M.D. History ... Robert H. Anderson.

Managements

• Surgery • reimplantation of the left coronary artery into the aorta

Paediatric Cardiology, 3rd edition: Robert H. Anderson.

Page 47: Interhospital Echo conference - Thai  · PDF fileInterhospital Echo conference Thida Yingchutrakul. M.D. History ... Robert H. Anderson.

Thank you for your attention


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