i
Canadian Institutes of Health Research
ANNUAL REPORT • 2011
International Infectious Disease & Global Health Training Program
© 2011-2012 Canadian Institutes of Health Research, International Infectious Disease & Global Health Training Program (CIHR IID, IID, and the training program)
Table of Contents
OBJECTIVES ............................................................................ 1
TRAINEE SPOTLIGHT ............................................................... 2
GRADUATES AND WHERE THEY ARE NOW ............................ 5
RECRUITMENT ........................................................................ 6
LIST OF TRAINEES AND PROJECTS .......................................... 6
FUNDING & ACADEMIC PARTNERS ........................................ 8
ACADEMIC PROGRAM ........................................................... 9
INFECTIOUS MINDS SCIENTIFIC DISCUSSIONS ....................... 12
PRACTICA 2011 REPORT ......................................................... 14
INTERNATIONAL HIV PREVENTION EXCHANGE ..................... 15
PROGRAM ADVISORY COMMITTEE ....................................... 16
PLANS FOR 2012 ..................................................................... 16
IID in Bangalore, India for the 2011 Major Course Planning, Implementing, and Evaluating Scaled HIV Prevention and Care Programs among Vulnerable Populations in Resource Poor Settings.
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OBJECTIVES
1. Toequiptraineeswiththeresearch,scientificknowledgeandskillstobecomeoutstanding researchers ininfectiousdiseasesandglobalhealth.
2. To create a novel and stimulating multidisciplinary and truly international research training environment that fosters creativity,opportunity,andinnovation,andonethatdemandsexcellence.
3.To harness the unique opportunity offered by the critical mass ofinfectious diseases and global health infrastructure, researchopportunities and outstanding scientists in the training of the nextgenerationofinfectiousdiseaseresearchers.
4.Tomake availablecollaborative international research sites for thetrainees’primaryresearchprojects,sitesforresearchpracticaandmajorcourseofferings.
5.To offer a shared learning environment, where trainees andmentorsfromallfourofCIHR’sresearchpillarsandthefourinternationaltraining sites work cooperatively to explore issues of internationalinfectiousdiseasesandglobalhealth.
TRAINEE SPOTLIGHTNadia Musimbi ChanzuisaPhDstudentinInfectiousDiseaseat theUniversityofNairobi,Kenyaunder thesupervisionofProf.WalterMwanda,Prof.OmuAnzalaandDr. JuliusOyugi.Nadia applied to the trainingprogrambecauseshewasinterestedintheopportunitytoinvestigateinfectiousdiseasesinKenyawhicharenowbecoming increasingly available froma technologicalstandpoint,however,themanpowerandexpertisewerelacking.Sincejoiningtheprogramin2011,NadiahasbeenawardedanHIV/AIDSPreventionTrialsCapac-ityBuildingGrant from theGlobalHealthResearchInitiative-InternationalDevelopmentResearchCentre(GHRI/IDRC).HerPhDresearchfocusesonSecretorStatus,Fucosyltransferase2(FUT2)GenePolymorphismsandSusceptibilitytoHIVInfectionamongFemaleSexWorkersinKenyawhichisdesignedtoexplorethevari-ableexpressionofbloodgroupantigensinthecontextofHIVresistanceinordertobetterunderstandthemucosalmechanismsofprotectionassociatedwithbloodgroupantigenexpressionprofiles. Inconductingthis researchNadiahopestoprovideadditionalinsightintothedevel-opmentofnewHIVpreventivetechnologies.
Nadia’s favouriteaspectof the trainingprogram is theInfectiousMindssessions.AsabasicscientistshefeelsthatthediversityoftheInfectiousMindssessionsprovideanexcellentopportunityforhertobroadenherscopeandknowledgebeyondHIVandImmunology/Haematology.Also shehas found that the InfectiousMinds sessionsallowedhertogainamorecomprehensiveunderstandingofscience,beyondbasicscienceandHIVresearch,whichshecreditstopresentationsgivenbyexpertguestspeakerswhohavediversebackgrounds.
Elizabeth Cooper, aPhDStudentinCommunityHealthSciencesattheUniversityofManitobaandatraineeintheIIDprogram,hasaBachelorsdegreeinReligiousStudiesandHistory,andaMastersdegreeinNativeStudies,bothfromtheUniversityofManitoba.
Nadia Musimbi Chanzu
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Elizabethisinterestedincommunitybased,participatoryactionandhealthdecision-makingamongIndigenouscom-munities.ThecommonthreadthathasalwaysconnectedtheworkElizabethdoesisthedesirefordifferentvoicestobevisiblewithintheoverarchingfabricofmain-streamsociety.ThroughthecourseworkinElizabeth’sPhDprogram,com-binedwiththeopportunitiesaffordedbytheIIDprogram,Elizabeth isgainingworkingknowledgeofbiostatistics,epidemiology,microbiology,economicsandpolicyforma-tion.Shebelievesthatworkingwithinaninterdisciplinaryacademicenvironmentiskeytocreatingopportunitiestoenactchangewithintheworld.Workingwith,andlearn-ingfrom,individualswithdiversebackgroundsallowsfordifferentviewstobeseenandactualized.
OneofthemostpoignantmomentsElizabethhasexperi-encedaspartofthetrainingprogramoccurredduringoneofthelearningvisitsinIndia.Membersfromalocalnon-governmentalorganizationsangfolk-songstothetraininggroupandElizabethandsomeofhertrainingcolleaguesandadvisorssangsomefolk-songsfromCanadainreturn.TheindividualsfromIndiasaidthattheyalwayssingforvisitors,butthisisthefirsttimetheycouldrememberpeoplesingingforthem.ThiseventhighlightedtoElizabeththeneed forongoingdiscoursebetweenorganizationsandindividualsaswellastheongoingneedfordifferentmodesofknowledge-translation and trust-building activities.BeingabletolearnaboutdifferenttechniquestoconnectwithpeopleinameaningfulwaythatisappropriatetothecontextisanintrinsicskillthattheIIDprogramworkstodevelopinallofitstrainees,andanimportantpiecethatisoftenmissingfromacademictrainingprograms.
Dr. Jayanna Krishnamurthy,aclinicianandcommunityhealthspecialistfromBangalore,India,joinedthetrainingprograminJanuary2011asaPost-DoctoralFellowtrainee.Hehas10yearsofexperienceimplementingpublichealthprogramsandconductingresearch in theareasofHIVandMother,NewbornandChildhealth(MNCH).His
Elizabeth Cooper
TRAINEE SPOTLIGHT, continued
researchfocusesonthequalityofMNCHinpublichealthfacilitiesofpoorperformingdistrictsinNorthKarnataka,India.Thestudyspecifically looksattheeffectivenessofonsitementoringprogramsbyacadreofnursementorstotheprimaryhealthcarecentersaboutthequalityofmotherandnewbornhealthservices.FindingsfromhisresearchhavethepotentialtoinfluencethepoliciesandprogramsinIndiainthewaytheylookatthequalityofMNCHcare.Asapartof the trainingprogram,Dr.Krishnamurthy attendedthe2011majorcourseinBangalore,IndiawhichwasaimedatprovidingthetraineeswithopportunitiestounderstandtheissuesandchallengesinimplementingHIVprograms inadevelopingcountry setting.Hesaid thatattendingthiscoursewithtraineesfrommultidisciplinarybackgroundsofferedauniqueadvantagetounderstandingdifferentperspectives,whichhefeelsisthebestpartoftheIIDprogram.
Dr.Krishnamurthyhadaveryeventfulyearin2011.Heco-authoredtwopeerreviewedarticleslookingatpositivepreventionpracticesandmorbidityprofilesofHIVinfectedindividualsincaresettingsinSouthIndia.HecontributedtoeightresearchreportsdescribingMNCHsituationsinNorthKarnatakadistrictsandhewasawardedthe“YoungScientistAward”fromtheKarnatakaAssociationofCom-munityHealth(KACH)fortheyear2010-11.ThisawardisaimedatencouragingyoungandbuddingpublichealthspecialistsinIndiatocontributetopublichealthprogramsandresearch.
Natalia Taborda-Vanegas isaPhDtraineeat theUni-versidaddeAntioquia,inMedellin,ColombiaunderthesupervisionofDr.MaríaTeresaRugeles.HerdoctoralthesisfocusesonHIVandthemechanismsrelatedtothecontrolofviralreplicationingut-associatedlymphoidtissueandperipheralbloodinHIVcontrollers.Dr.MaríaTeresaRugeles,whoisamentoroftheIIDprogramencouragedNataliatoenrollbecauseitwasagreatopportunityforhertolearnandworkwithresearchersfromseveralcountries.Nataliabelieves thatbecauseher fellow trainees come
Dr. Jayanna Krishnamurthy
Natalia Taborda-Vanegas
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fromdifferentepidemiological,socialandeconomicback-groundsthereareseveralpointsofviewcomingtogethertosolveacommonproblemandthisiswhatmakesthisprogramaninvaluablelifeexperience.
In2011,Natalia attend the“Planning, implementingandevaluatingscaledHIVpreventionprogramsamongvulnerablepopulationsinresource-poorsettings”courseinBangalore,India.Shesaiditwasanexcellentexperiencebecauseshewasabletoworkonaproposalaboutatopictotallydifferentfromherresearchareaand,therefore,wasabletolearnalotfromthecourse.Alltheactivitiesperformedintheprogramhaveenabledhertounderstandherresearchtopicfromawidepointofviewaswellashelpedhertoimproveherunderstandingoftheimportanceofherresearchandhowitcontributestosociety.Shebelievesthatthetrainingprogramwillhaveapositiveimpactinbothherfuturecareerasabiomedicalscientistandherpersonallife.
Graduates and Where They Are Now
Dr.ArupDassuccessfullycompletedhisPhDinPopulationScience/DemographyattheInternationalInstituteforPopulationSciencesinMumbaiunderthesupervisionofDr.SKSingh.Aswell,hegraduatedfromtheIIDprograminDecember,2011.Sincecom-pletingthetrainingprogram,AruphasbeenworkingasaMonitoringandEvaluationexpertfortheBillandMelindaGatesfoundationfundedproject“Integratedfamilyhealthinitiative”whichisaimedatimprovingmaternal,neonatalandchildhealthoutcomesinBihar,India.Arup’sroleintheprojectistodesignandimple-mentdifferentevaluationstudiesincludingrandomizedcontroltrials.AccordingtoArup,“themostvaluablecomponentofthetrainingprogramisitsmultidisci-plinarynature.Asasocialscientist,Inowdonotfeelconfinedonlytomydiscipline,myhorizonsarebroaderaftercompletingthecourse.Iamconfidentingettinginsidetheclinicalorbasicscienceaspectofpublichealthproblems;atleastIwillmakeanattempt.”
Dr. Arup Das
RECRUITMENT 2011 Intake at the University of Manitoba 6applicantswereaccepted(1Post-DoctoralFellowand5PhDs) 4BasicScienceand2SocialSciencePillar
Intake at the International Sites Bangalore,IndiaSite 3applicantswereaccepted(1Post-DoctoralFellow&2PhDs) AllarefromtheSocialSciencePillar
Nairobi,KenyaSite 1applicantwasaccepted(PhD) 1BasicSciencePillar
Medellin,ColombiaSite 1applicantwasaccepted(PhD)fromtheBasicSciencePillar
LIST OF TRAINEES AND PROJECTSPh.D. Trainees
Winnie Apidi TheglycolysispathwayinHIV-1resistanceCatherine Card RegulatoryTcellsandImmuneQuiescence:
amodelforresistancetoHIVinfectionNadia Musimbi Chanzu SecretorStatus,FUT2Polymorphisms
andtheRiskofInfectionbyHIVandHPVinFemaleSexWorkersinKenya
Dhanunjaya Chintada InterrelationbetweenStigma,discrimina-tionandimpactonutilizationofcareandsupportservices-AstudyamongHIVSeropositiveMenhavingsexwithMenandTransgender(MSM-T)inKarnataka
Suresh S. Chitrapu AstudyonviolenceamongwomenlivingwithHIV/AIDSinKarnataka
Elizabeth J. Cooper CulturallyRelevantHIV/AIDSPreventionProgrammingwithinCanadianAboriginalContext
Kallesh Danappa Jayappa ThemolecularmechanismofHIV-1nuclearimport:theroleofHIV-1integraseintar-getinghostnuclearimportmachineryanddeliveringviralcDNAintonucleus
Arup Kumar Das Psychosocial,BehavioralandContextualDeterminantsofSTI/HIVVulnerabilityamongFemaleWorkersinBars:Alifecycleapproach
Margaret Ormond a trainee of “University without Walls” and Natalia Taborda-Vanegas a trainee of the IID Train-ing Program during the 2011 India Major Course
Keith Fowke, James Sainsbury and Jayanna Krishnamurthy enjoying tea in India at one of the cultural exchange sites in Hampi
Trainees at a field placement site in Bellary during the Major Course
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Melissa Herman, Julie Lajoie, Meika Richmond, Aida Sivro, and Catherine Card during the opening reception
Cisily Meeme, Marion Kiguoya, Winnie Apidi, Ifeoma Okwor, Nadia Chanzu and Were Omange at the Major Course opening reception
Dhanunjaya Rao Chintada and Shamshad Khan on the bus
TRAINEES AND PROJECTS, continuedPh.D. Trainees
Melissa Herman HeterogeneityinProgressiontoAIDS:TheRoleof AntigenSpecificCD8+TcellsJennifer Juno TheRoleofGeneticPolymorphismsattheCD4 locusinHIVdiseaseprogressionYoav Keynan ImmunogeneticfactorsassociatedwithInfluenza
cross-protectionanddiseaseseverityMarion Kiguoya Astudytocorrelatelongtermnonprogressor
HIV-1isolateviralfitnessinhighlyexposedpersistentlyseronegative(HEPS)versuslowrisknegativeindividualsanditsassociationwithHLAsubtypes
Sajid Mahmood ExaminingNK–DCCrosstalkinNKdifferentia- tionandfunctionalpropertiesofNKcellsCisily Meeme EvaluationofDrugResistanceProfilesandViral CharacteristicsinHIV-1VirusesfromInfected PatientsBeforeandAfterReceivingAntiretroviral TherapyIfeoma Okwor RegulationofSecondaryAnti-LeishmaniaImmunityRobert Were Omange Linkageofinnateandadaptiveimmunityin
HIV-1resistantwomeninNairobi.Michael Babu Raj PPTCTServices:AreWeReachingOut?From HumanRightsPerspectiveMeika Richmond PolyfunctionalityandproliferationofCD8+Tcells inchronicandacuteHIVinfectionZulma Vanessa Rueda Epidemiologicandclinicalcharacteristicsof Mycobacteriumtuberculosisinprisonersatfour differentjails,Colombia2010-2012Souradet Shaw Understandingautoimmunediseases:combining traditionalepidemiologicaltechniquesandcomplex systemsapproaches Dan Alex Silaghi Identificationofvirulencedeterminantsinthe 1918InfluenzaHemagglutinin(HA)andH1N1fluAida Sivro TheRoleofIRF-1Polymorphismsinsusceptibility toHIV-1InfectionDerek Stein MassSpectrometrybasedcharacterizationof HIV-1resistanceinthefemalegenitaltractMichael Stobart IdentificationofNon-EssentialHostGenes RequiredforPrP106-126MediatedNeurotoxicityNatalia Taborda -Vanegas Evaluationofgeneticandimmunological mechanismsinvolvedinresistancetoHIV-1 exhibitedbychronicallyinfectedindividualswho controlviralreplicationwithoutantiretroviralsYingfeng Zheng Functionalroleandmolecularmechanismunderly- ingtheinterplayofHIV-1integrasewithhost cofactors
TRAINEES AND PROJECTS, continuedPost Doctoral Fellow Trainees
Zhujun Ao Investigationofthemechanismunderlyinganti-HIVactionofR88-A3G:Developmentofapotentanti-HIVapproachinprimaryCD4+Tcellsandmacrophages
Kaveri Gurav Vulnerabilitiesassociatedwithmigrationoffemalesexworkers(FSWs)inIndia
Jayanna Krishnamurthy IntegratingHIVintoGeneralHealthSystems;OpportunitiesandChallengesinIndiancontext
Shamshad Khan Community-basedOwnershipandUptakeofFutureHIVVaccineProgramsamongMSMandFSWsinIndia
Julie Lajoie Mucosalimmuneactivationincommercialsexworkers
Lyle McKinnon Effectofantiretroviraltherapyonmucosalimmunologyinfemalesexworkercohorts
James Sainsbury CharacterisationofanovelcandidategenefortheHIV-1ResistancePhenotypeinthePumwaniSexWorkerCohort
FUNDING & ACADEMIC PARTNERSFunding PartnersCanadianInstitutesofHealthResearch(CIHR)ManitobaHealthResearchCouncil(MHRC)NationalCollaboratingCentreforInfectiousDiseases(NCCID)NationalMicrobiologyLaboratory(NML)NaturalSciencesandEngineeringResearchCouncil(NSERC)ProvinceofManitoba–Innovation,EnergyandMinesUniversityofManitobaKenyaAIDSVaccineInitiative(KAVI)Colciencias
Academic PartnersCentreforAboriginalHealthResearchSt.John’sMedicalCollegeUniversityofNairobiUniversityofManitobaCentreforGlobalPublicHealthUniversityofWinnipegGlobalCollegeInfectiousImmunologyResearchInterestGroupUniversityofTorontoJointCentreforBioethicsUniversityofIndianaCentreforBioethicsUniversidaddeAntioquia
Zulma Rueda, Yoav Keynan, Nadia Chanzu, Souradet Shaw and Lyle McKinnon during a site visit
L-R: Derek Stein, Dhanun-jaya Rao Chintada, Jennifer Juno, Keith Fowke, Kaveri Gurav, Mahesh Doddamane and Elizabeth Cooper in front of Shiv Sangam Residency in Bagalkote
Jayanna Krishnamurthy, Ifeoma Okwor, Catherine Card, and Cisily Meeme in Hampi
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ACADEMIC PROGRAM“Planning, implementing and evaluating scaled HIV prevention programs among vulnerable populations in resource-poor settings”by Dr. Srinath Maddur, Ms. Parinita Bhattacharjee and Dr. Stephen Moses
ThecourseconsistedofafewdaysoffoundationalpresentationsandsomesitevisitsinBangalore,Indiafollowedbylearningvisitstooneofsixfieldsites.ThetraineesweregivenanassignmentatthefieldsitestodesignandpresentHIVinterventionprogramsforaparticularhighlyvulnerablegroup.AworkshoponplanningimplementingandevaluatingscaledHIVprevention,careandsupportprogramsamongvulnerablepopulationsinIndia(femalesexworkers[FSWs]andmenwhohavesexwithmenandtransgenderedindividuals[MSM-T]),wasjointlyconductedbytheIIDprogramandtheKarnatakaHealthPromotionTrust(KHPT)forIIDfellowsfromFebruary14-25,2011,inKarnatakastate,India.Theworkshopwasdesignedtoinform,engageandchallenge the fellowswith respect tokey issues inHIV/AIDSprevention,careand supportprogramming. It consistedof severalmodules,usingaparticipatoryandexperientiallearningprocess.TheworkshopaimedatbuildingabroadknowledgebaseregardingHIV/AIDSprevention,careandsupportissuesinaresource-poorsetting.Fellowswereintroducedtotheprocessesofplanning,designing,imple-menting,monitoringandevaluatingHIV/AIDSprogramsfocusedonthemostvulnerablepopulations.
Theworkshopstressedthescientific,social,behaviouralandhealth-relatedaspectsofHIV/AIDSprogramming.Itbeganwithpresen-tationsandfieldvisitsinBangalore,whereKHPT’sheadofficeislocated,andlaidafoundationinunderstandingHIVepidemiol-ogyandimportantperspectivesaroundHIV/AIDSissues.Thisintroductiongavethefellowsafirst-handexperienceoftheHIV/AIDSepidemic.Thefellowswerethendividedintosixgroups,andtravelledtovarioussitesinruralKarnataka,wheretheywereexposedtoactualprogramsituations.Atthesefieldsites,theyweregiventhetaskofdevelopingvariousproposalsonrelevantandchallengingtopics.EachgroupspentapproximatelyfivedaysinteractingwithvulnerablecommunitiesofFSWsandMSM-T,assessingtheirneedsandunderstandingtheirchallenges.TheythendevelopedresearchandactionproposalsthataddressedaspectrumofHIV/AIDSpreventionandcareissues.ThefellowsthenreturnedtoBangalore,wherethegroupspresentedtheirproposalstoapanelofexperts.Proposalswereratedfortheirunderstanding,feasibilityandpracti-cability,andweregradedaccordingly.Thequalityoftheproposalsdevelopedwasuniformlyexcellent,andKHPT,incollaborationwithsomeofthefellows,hasfurtherdevelopedsomeoftheseproposalsforimplementation.
Meika Richmond, James Sains-bury, Ms. Shama Karkal, Director (Learning Systems at Swasti – Health Resource Centre), Natalia Taborda-Vanegas, Ifeoma Okwor and Zhujun Ao at Swasti
Trainees at Swathi Mahila Sangha which provides services to commercial sexworkers
Trainees at an orphanage for HIV infected children in India
ACADEMIC PROGRAM, continued
Feedbackfromthefellowsindicatedthattheyfoundtheexperiencetobevaluableandenriching,andthattheywereabletodevelopamuchdeeperunderstandingregardingavarietyofHIV/AIDSissuesintheIndiasetting.Theyalsoacquiredknowledgeanddevelopedskillsinprogramdesign,implementation,monitoringandevaluationwhichwillbeofgreatvaluetothemintheirfuturework.
TRAINEE PERSPECTIVE
Thearticle“CommunityMatters”Newsletter,FacultyofMedicine,UniversityofManitoba,Dept.ofCommunityHealthSciences,Issueno.39,April2011,page8-9waspublishedbyElizabethCooper,ProgramTraineeabouttheIndiamajorcourse.
InFebruary,theCIHRInternationalInfectiousDisease&GlobalHealthTrainingProgram(IID)offeredatendayintensivecourserunbytheKarnatakaHealthandPromotionTrust(KHPT)inBangaloreIndiaentitled:Planning,implementingandevaluatingscaledHIVpreventionprogramsamongvulnerablepopulationsinresourcepoorsettings.Thirty-onetraineesfromCanada(UniversityofManitoba),Colombia(UniversidaddeAntioquia),India(St.JohnsUniversity),andKenya(UniversityofNairobi)cametogetherforthisuniquelearningopportunity.TheCIHRIID’sthemeis“fourcontinents,onesharedexperience”andthecourseinIndiastrovetomakemultidisciplinaryinternationalhealthresearchanembodiededucationalexperienceforthoseinvolved.
InpreparationforafivedayfieldvisitinruralIndia,thefirstdayoftrainingfocusedonacademicpresentationscontextualisingHIV/AIDSwithinIndia.Onthesecondandthirddayoftrainingwewenttovisitthreesocialorganizations,ontheseconddaywevisitedanorganizationthatworkswithFSWandanorganizationthatworkswithMSM.Bothorganizationsprovideadvocacy,healthandsocialsupportfortheirmembersandextendedsocialnetworks.Wehadtheopportunitytohearapresentation,haveteaandvisitwithbothstaffandclients.ThestafffromKHPTtranslatedHindi/KannadaandEnglishaspeoplehappilysharedstoriesaboutvariousexperiencesrelatedtotheirworkandpersonalliveswiththetrainees.Inthelateafternoonwewentonawalkingtourtositeswherecondomsaredistributedtoindividualswhofrequentlyengageinsexworkorrecreationalsexualactivities.HalfofthetraineeswenttoalocalbusstationsituatedinabustlingnoisyareaofBangalorewithnumerous
A condom drop site in Banga-lore, India to prevent MSM HIV transmission
Dr. Washington at The Catho-lic Order of Saint Camillians’ Orphanage
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shops,restaurants,publicwashrooms(wherecondomsareleftintubesforeasyaccessbyFSW),andhotels.Theotherhalfwenttoalargepublicpark,meetingwithMSMwhowererelaxingattheendofalongday(condomsareleftincasesunderidentifiedbambootreesforeaseofaccessbyMSM).AdaylongvisittoSnehadaan,aPLHA,palliativecarecentre,supportservicescentre,andorphanageprovidedfurtherinsightintodisparitiesfacingindividualsaffectedbyHIV/AIDSinKarnataka.Watchingtrainees,aswellasKeithFowketryingtolearnyogafromafewoftheHIV/AIDSaffectedorphanswascertainlyahighlightofthetrainingprogramforeveryone-especiallythechildren.
Ondayfourwepackedourbagsandboardedanovernighttrain(orbus)forruralIndia.ThetraineesweredividedintogroupsoffiveandsenttoruralareastoexaminekeyissuesaroundHIV/AIDS.Attheendofourfivedayfieldvisit,afternumeroustrainingopportunitiesincludinginformalinterviews,focusgroupsandmeetings;wecreated“outofthebox”interventionproposals,presentedattheendofthecourse.
Theissuesexaminedincludedidentificationofnewfemalesexworkers,condomusewithintimatepartners,economicstrategiestoassistwidowsaffected/infectedbyHIV,improvedaccesstohealthcareforMSM,improvedfostercareforchildrenaffected/infectedbyHIV,aswellasGISasadecisionmakingtool.
TheentireinternationallearningexperienceinIndiawasvaluable.Workingasinternationalgroups,withinaninternationalcontext,comingfrominterdisciplinaryacademiccontexts,learningside-by-side,eatingIndianfood(withtheoccasionalwesternKFCmealorpastadishprovidedbyKHPTforthosewhomissedtheirNorthAmericandiets),visitingtemples,shoppinginbazaars,laughingatmonkeysastheyclamoredonvehicles,lookinginaweattheelephantsandcowsthatwalkedby,andmostimportantlyhavingtheopportunitytospendtimewithpeopleworkingwith,livingwithandaffectedbyHIV/AIDS.Thisuniquetrainingofferedanexperiencenoneofuswillsoonforget.
CIHR IID Program 2011 Scientific SymposiumTheScientificSymposiumwasheldonFebruary25,2011at theKHPTofficesinBangalore,India.Thesymposiumhighlightedeachtrainee’sresearchandthetraineesinvitedaguestspeakertotakepartinthesymposium:Dr.SKSingh,AsstProfessor,DeptofMathematicalDemographyandStatistics,IIPS,Mumbai.
Nadia Chanzu, Shamshad Khan, and Yingfeng Zheng
INFECTIOUS MINDS SCIENTIFIC DISCUSSIONS
Thepurchaseofvideoconferenceequipmentforeachinternationalsitehasenabledimportantscientificdiscussionstotakeplaceinrealtimeandhasallowedthesmallersitesthebenefitof“criticalmass”. In2011,nine InfectiousMindsmeetingswereconductedwitheachsessionbeingorganizedbyateamofthreetrainees.Theteamresponsibleforthesessiondecidedonatopic,invitedaguestspeaker,presentedtothegroupandheldaquestionandanswer/discussionsession.TheInfectiousMindsmeetingsarecoordinatedbyDr.JavierMignone,amentorofthetrainingprogramandapasttrainee.
The Infectious Minds meetings held in 2011
January 19GuestSpeaker:CharleneRanadheeraPresenting:YingfengZheng,SouradetShaw,AlexSilaghiTopics:Henipavirus,NipahandHendraVirusesasexamplesofidentificationandmanagementofnewemerginginfections;Labidentificationofvirus,epidemiologicalstudies/patternsinemerg-ingvirusesandmolecularbiologyofNipahviruses
March 16GuestSpeaker:AlbertoSeveriniPresenting:IfeomaOkwor,ShamshadKhan,JulieLajoieTopics:HPV,CervicalcancerscreeningandHPVvaccination,HPVvaccinationinmales,IncidenceandclearanceofgenitalHPVinfectioninmen
April 27, 2011GuestSpeaker:AshleyHaasePresenting:DerekStein,RobertWereOmange,AidaSivroTopics:MucosalImmunologyandVaccination
MAY 25, 2011GuestSpeaker:PamelaOrrPresenting:MelissaHerman,SajidMahmood,JayannaKrishnamurthyTopics:Tuberculosis
Manitoba based IID trainees duringtheSeptember2011InfectiousMindsmeeting
Pamela Orr, presenting her guest lecture for the May 2011 Infectious Minds meeting
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INFECTIOUS MINDS continued...
The Infectious Minds meetings held in 2011, continued
JUNE 22, 2011 GuestSpeaker:MargaretLavalleePresenters:NadiaChanzu,ElizabethCooper,KalleshDanappa
JayappaTopic:TraditionalMedicine
SEPTEMBER 21, 2011 GuestSpeaker:FranciscoJavierDiazPresenters:MarionWanguiKiguoya,JamesSainsbury,
NataliaTaborda-VanegasTopic:DengueFever
OCTOBER 13, 2011 Presenters:WinnieApidi,KalleshDanappaJayappa,
LyleMcKinnonTopic:NeglectedTropicalDiseases
NOVEMBER 17, 2011 GuestSpeaker:Dr.(Major.Rtd)ChristopherStuartGontierPresenters:NadiaMusimbiChanzu,DhanunjayaRaoChintada,
KaveriGuravTopic:Autoimmunity
DECEMBER 15, 2011GuestSpeaker:RonDaganPresenters:YoavKeynan,JulieLajoie,SajidMahmoodTopic:EffectsofPneumococcalVaccines,Introductionontheepidemiologyofpneumococcaldiseases
Melissa Herman, a presenter during the May 2011 Infectious Minds meeting
Above: Keith Fowke and trainee Souradet Shaw during the discus-sion session of the September 2011 Infectious Minds meeting
Left: Lazaro Velez, Keith Fowke, María Teresa Rugeles, Natalia Taborda-Vanegas, Zulma Rueda, Carlos Rojas, and John Wylie after an Infectious Minds meeting in Medellin, Colombia
Practica 2011 ReportTheintentionofthepracticumportionoftheCIHRInternationalInfectiousDisease&GlobalHealth(IID)TrainingProgram,coordinatedbyDr.JohnWylie,istoexposetraineestoacompletelydifferenttypeoflearningexperienceapartfromtheirmainresearchareaandtofosterinterdisciplinaryresearch.Thepracticaareintendedtolastfromfourtotwelveweeksandtobetailoredtothespecificgoals,objectivesandtimelinesofeachtrainee.TodateallinformationaldocumentsrelatedtothePracticumportionoftheIIDprogramhavebeenprepared.Thesedocumentsareintendedtoactasaguidefortraineestoassisttheminsettinguptheirpracticum.Thesedocumentsconsistofastep-by-stepguideforthetraineestohelpthemsetuptheirpracticum,asetofquestionsthatthetraineescanusetohelpthemdevelopaframeworkforwhattheywouldliketogetoutoftheirindividualpracticumandalistof20possiblesitesthetraineescouldconsiderasapossibletrainingsite.Traineesarealsoencouragedtoseekoutothersites,asapplicable,toreachtheirrespectivepracticumgoals.Finally,apracticumevaluationformhasbeendevelopedwhichallowstraineestheopportunitytoprovidefeedbacktotheIIDprogramontheircompletedpracticumexperience.AsofSeptember2011,twotraineeshavecompletedtheirpractica.Abriefdescriptionofthesepracticaareprovidedbelow:
James SainsburyhascompletedhispracticuminOttawawithLiniAl-Kharki,PublicHealthLawandEthicsProgram,PubicHealthAgencyofCanada.HispracticumsupplementedhisbasicsciencePDFresearchbyprovidinghimwithexperienceinpolicydevelopment.
Zulma RuedapursuedherpracticumwithDr.Bangdiwala,DepartmentofBiostatistics,UniversityofNorthCarolinaatChapelHill.Herpracticumsupplementedherepidemiology-basedPhDResearchbyprovidingbasicexperienceinbiostatisticalmethodologyapplicabletotheanalysisofdataarisingfromherPhDresearch.
AvideoconferencemeetingwithalloftheremainingtraineesoccurredinNovember2011toreviewthepracticumrequirementoftheIIDprogramtoprovidefurtherassistancetotheminsettinguptheirpracticum.PossiblechangestothisportionoftheIIDprogramarebeingconsideredtoallowtraineestoengagein“skilldevelopment”andacquirenewresearchskillsthatarecloselyrelatedtotheirprimaryresearchprograms,butunavailablewithintheirsupervisor’sresearchteam.Thischangeisbeingconsideredtomaximizetheusefulnessofapracticumexperienceforboththetraineeandtheirsupervisor.
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L-R: Vincent Ho, John Corigliano, Alex-ander Mickelthwate, Frank Plummer, and Keith Fowke at the NMF
L-R top: Jude Zieske, Lynn Gauthie, Michelle Driedger, Joshua Kimani, Frank Plummer, Javiar Mignone, Carlos Rojas, L-R bottom: Lesley Slaney, Adrienne Meyers, and Keith Fowke during the NMF
International HIV Prevention ExchangeTheUniversitiesofManitoba&NairobiHealthInitiative(UMNHI)collaboratedwiththeWinnipegSymphonyOrchestra(WSO)duringtheNewMusicFestival(NMF)tobringforththeInternationalHIVPreventionExchange.
OnJanuary29,2011,theWSObroughtbackJohnCorigliano’sSymphonyNo.1aspartoftheiropeningnighttotheNMF.ThisworkwascomposedbyCoriglianoashispersonalresponsetotheAIDSepidemicduringthelate1980s.
Tocoincidewiththeperformance,theUniversityofManitobaandtheIIDprogramorganizedanInternationalHIVPreventionExchange(TheExchange)whichwasheldinWinnipegonJanuary28-29,2011tocreateadiscussiononHIVresearch.Thetwo-daysymposiaandworkshopsculminatedwiththeopeningnightoftheWSO’sNMFandincludedapre-concertvideopresentationoftheHIVprojectworkinNairobiandIndia.
TheExchangewaschairedbyDr.KeithFowke,Dr.MarissaBeckerandDr.JamesBlanchardandwasorganizedbyagroupofpeoplefromtheMedicalMicrobiologyandCommunityHealthSciencedepartmentsattheUniversityofManitobaleadbyJudeZieske,LynnGauthier,andDr.AdrienneMeyers.
ManyofthepresentersandthoseinattendanceincludedtraineesandleadersintheCIHRInternationalInfectiousDiseaseandGlobalHealthTrainingProgram.ItbroughttogetherlocalandinternationalresearchersandcreatedawarenessofHIVresearchanditsglobalimpacttothosetakingintheWSOconcert.
Dream Catchers Drum Group perform-ing during the Scientific Symposium for “The Exchange”
Baby Elephant at the Elephant Sanctuary outside of Nairobi, Kenya
Maasai Warrior Statuette
PROGRAM ADVISORY COMMITTEE TheProgramAdvisoryCommittee (PAC) is composedof keystakeholders suchasgovernment, industry,communitymembers,non-profitsector,academia, internationalpartnersandoneofourtrainees.ThiscommitteewasstruckinMarch2010andDr.GaryGlavin,AssociateVice-President(Research)acceptedtheinvitationtoserveasthePACChair.TheresponsibilitiesofthePACaretoadvisethePrincipalInvestigatorandCoreCommittee(Drs.Fowke,Wylie,Mignone,andMoses)oftheprogram,providerecommendationsandfeedbackwithregardtotheprogramgoals,visionandresponsibility.ThefirstmeetingofthePACtookplaceonMay12,2010andasecondmeetingwasheldonOctober14,2011.
Dr.KeithFowkeasked the international sites (India,KenyaandColombia) toupdate thePACmembers on theprogram.ThehighlightsfromthemostrecentmeetingweretheInfectiousMindsScientificVideo-conferencesessionsandanupdateonframeworkofthePracticumportionoftheprogramrequirements.
PLANS FOR 2012ThetraineeswillbeinNairobi,Kenyatoattendthe“ClinicalTrialsandResearchEthicsinaDevelopingCountrySetting”coursefromJanuary29–February12,2012hostedbytheKenyasiteleaderDr.JuliusOyugi.
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CanadianInstitutesofHealthResearch(CIHR)InternationalInfectiousDiseaseandGlobalHealthTrainingProgram(IID)
Address:UniversityofManitoba,Dept.ofMedicalMicrobiologyRoom514C,BMSB,745BannatyneAvenue.Winnipeg,MB,CANADAR3E0J9
Phone:(204)789-3307
Fax:(204)789-3926
E-mail:[email protected]