INTERVENTION TEST OF TRAINING
AND
SUPERVISION ON PRESCRIBING PRACTICES
Submitted to
USAID/RPM/JSI, Nepal
August, 1995
Kathmandu, Nepal
CONTENTS
Page No
CONTENTS i-ii
ACKNOWLEDGEMENT iii
PERSONNEL INVOLVED iv
EXECUTIVE SUMMARY v-vi
INTRODUCTION
1. BACKGROUND 1
2. PURPOSE AND SIGNIFICANCE 2
2.1 Study Objectives 2
2.2 Significance of the Study 2
METHODS
3. OVERALL APPROACH AND DESIGN 3
4. DETAILED METHODOLOGY 3
4.1 Sample Selection 3
4.2 Instruments 5
4.3 Intervention Strategy and Implemention 6
4.4 Recruitment, Orientation and Supervision of 7
Survey Team
4.5 Secondary Coding 7
4.6 Data analysis 11
i
Page
RESULTS
5. PRESCRIBING PRACTICES 12
5.1 Percentage of Prescriptions Inaccordance with SDTS 12
5.2 Percentage of Encounter With an Injection 12
5.3 Average Consultation Time 13
5.4 Percentage of Encounter with an Antiabiotic 13
Prescribed
5.5 Average Number of Drugs Prescribed 13
5.6 Percentage of Drugs Prescribed by Generic Name 14
5.7 Percentage of Drug Prescribed on EDL 14
5.8 Percentage of Drugs Actually Dispensed 14
5.9 Percentage of Reviewed Cases With Adequate 15
Examination
5.10 Percentage of Availability of Key Drugs 15
5.11 Avability of EDL, SDTS and other
Impartial Information 15
6. PRESCRIBER KNOWLEDGE
6.1 Diarrhoea 16
6.2 ARI 16
6.3 Peptic Ulcer 16
6.4 Anaemia 17
6.5 Scabies 17
6.6 Conjunctivitis 17
6.7 Ascariasis 17
6.8 UTI 17
6.9 Referral 17
CONCLUSION 18
REFERENCES 19
ANNEXE ii
ACKNOWLEDGEMENT
We express sincere thanks to Dr P.C Karmacharya, Dean, Institute
of Medicine for administrative support.
We are grateful to USAID/JSI particularly, Mr. Mathew Friedman,
Mr. Brice Atkinson and Dr. Penny Dowson, for financial support and
for having study done through INRUD, Nepal.
We are grateful to RPM Team member, particularly Mr James Bates,
Dr. R.O.Laing, and Dr. Budiono Santoso for valuable guidance and
support.
Thanks are also due to Department of Health Services, Department
of Drug Administration (DDA) in particular, Dr. Asfaq Sheak,
Chief Drug Administrator, and Nepal Chemist and Druggist
Association for their valuable help in carrying out this study.
We express thanks to District Health Officers, particularly Dr.
T.N.Jha, Late Dr.G.R. Karki, Dr. R.L. Karwa, Dr. V.K.Singh, Dr.
S.S. Jha, Dr.(Mrs) S. Verma, Dr. G.P. Ojha, and Dr. B.R. Bhatta;
District Public Health Officers, in particular, Mr. H.N. Yadav and
Mr. S.B. Verma and members of research team for their co-
operation, and hard and sincere work.
Lastly but not the least, we would like to thank Ms. Jeanne Madden
for helping us in developing the proposal, Mr. Iswor Bahadur
Shrestha and Mr. Arjun Pandey for statistical work, Mrs.Jyoti
Shrestha of HLMC for language editing and Mr. Kumar Prasad Baral
for data compilation, analysis and report typing.
Research Team
INRUD, Nepal
iii
PERSONNEL INVOLVED
1. Principal Investigator
Prof. Kumud Kumar Kafle
2. Co-principal Investigator
Mr. Ananda Dev Shrestha
Mr. Shiba Bahadur Karkee
Dr. B.P. Yadav
Mr. Radha Raman Prasad
3. Assistant Investigator
Mr. Naveen Shrestha
Mr. Prabhakar Lal Das
4. Consultant
Dr. Yogendra Man Singh Pradhan
5. Resource Person
- Dr. Tara Nanda Jha ( DHO, Jhapa)
- Dr. Shiva Shanker Jha ( DHO, Sarlahi)
- Dr. Bhoj Raj Bhatta (DHO, Kanchanpur)
iv
EXECUTIVE SUMMARY
Study Objective
The objective of the study was to evaluate :
- the impact of interventions - regular supervision/
monitoring and training using SDTS on the prescribing
patterns in HPs and SHPs.
Sample and Technique
The study was conducted in Nine Terai districts grouped into
control, intervention I and II; each group comprised of 21 health
facilities (3 X 4 HPs and 3 X 3 SHPs) from three districts.
Intervention group I was assigned training.
The training to prescribers was to be provided by UNICEF but it
could not take place during the study.
Intervention group II was assigned supervision/monitoring with
feedback .
Group III was control group having no intervention.
All three groups were evaluated for practices by observation
technique using WHO indicators.
For evaluating the knowledge, an interview was conducted using
structured questionnaire in post-test only.
Results
Prescribing Practices
The following results were obtained following supervision/
monitoring:
- Consultation time increased significantly .
- Prescriptions in accordance with Standard Drug Treatment
Schedule (SDTS) increased significantly.
- Injection encounter decreased significantly.
In the case of intervention I, consultation time decreased,
injection encounter increased and prescription in accordance with
SDTS decreased .
v
Prescribing Knowledge
The following results were obtained in the post-test:
- The correct knowledge of history taking for diarrhoea ,
peptic ulcer, ARI, aneamia, scabies and conjunctivitis
was less in intervention II than in control group.
- The knowledge of adequate examination for peptic ulcer
was more in intervention II than in control group.
- The knowledge of drug use for ARI and ascariasis was
more in intervention II than in control group .
- The appropriate knowledge of referral for UTI and
rheumatic fever was less than control group in
intervention II .
- The correct knowledge of history taking for diarrhoea,
peptic ulcer and anaemia was more than control group in
intervention I.
- The knowledge of adequate examination for ARI, peptic
ulcer and scabies was more than control group in
intervention I .
- The knowledge of drug use for ARI and peptic ulcer was
more than control group in intervention I.
- The appropriate knowledge of referral for rheumatic
fever was less in intervention I than in control group.
vi
INTRODUCTION
1. BACKGROUND
The study conducted in health posts of Kathmandu, Patan and
Bhaktpur showed most of the prescribing inconsistent with Standard
Drug Treatment Schedule (SDTS) for health post . The same study
showed only 56% of patients had knowledge of dosing [1,5]. The
study in other district also had similar findings [2]. However,
the practice of prescribing and dispensing is affected by several
factors.
To improve prescribing habits a mixture of strategies has been
found to be the most effective, which includes training in the use
of Standard Treatment Protocols, a small list of necessary drugs,
structured drug ordering forms, regular supervision and in-
service education on specific diagnostic areas [3].
HMG, Nepal, has decided to implement a Community Drug Programme
(CDP) to improve supply, and prescribing and dispensing through
training.
The rational use of drugs can be measured by using WHO indicators
[4]. These indicators can be used to measure impact of
intervention. The indicators can also serve as simple supervisory
tools to detect problems in performance by individual prescriber,
dispenser or health facility.
2
2. PURPOSE AND SIGNIFICANCE
2.1 Study Objectives
The specific objective of this study was:
- to evaluate the impacts of two interventions- regular
supervision/monitoring and training using a Standard
Drug Treatment Schedule (SDTS) on the prescribing
patterns in health posts and subhealth posts.
2.2 Significance of the study
This evaluative study has identified the most appropriate way
to implement the STDS, in terms of behavioural change and
cost effectiveness to prescribers. However, training to
prescribers by UNICEF using SDTS as designed in intervention
strategy could not take place.
The study was significant in evaluating the supervision/
monitoring strategy, which could be introduced in the health
system in improving rational prescribing.
3
METHODS
3. OVERALL APPROACH AND DESIGN
The study was conducted in Nine Terai Districts and consisted of:
a. interview with prescribers;
b. interview with patients/patient attendants;
c. observation.
The unit of analysis was health institution. Prescribing, Patient
care and Facility indicators were applied.
4. DETAILED METHODOLOGY
4.1 Sample Selection
The study was conducted in Nine Terai Districts.
Three Terai districts were randomly selected from the five
initial districts where UNICEF training on the SDTS as a part
of National Drug Scheme implementation was proposed. This was
labelled Group I.
An other three Terai districts were randomly selected from 17
Terai districts. This was labelled Group II.
Another three districts were randomly selected from the
remaining Terai districts and was labelled Group III.
Altogether Nine districts, all from Terai, were covered and
grouped as given below:
Group I: Morang, Dhanusha and Kailali.
Group II: Jhapa, Sarlahi and Kanchanpur.
4
Group III: Siraha, Chitwan and Bardia.
5
Selection of Health posts and Subhealth posts
From each district four health posts (HPs) were randomly
selected. In addition, three subhealth posts (SHPs) were
selected from the nearby selected health posts, making a
total of seven facilities per district. In total, there were
21 facilities in each group.
Group I
Morang
1. Tankisinuwari HP 2. Bayarban HP
3. Haraincha HP 4. Dadarbairiya HP
5. Nochha SHP 6. Pathari SHP
7. Sanischare SHP
Dhanusha
1. Parbaha HP 2. Ghodghas HP
3. Dhalkebar HP 4. Sinurjora HP
5. Sapahi SHP 6. Bateshwore SHP
7. Bhuinchakkarpur SHP
Kailali
1. Basauti HP 2. Pahalmanpur HP
3. Chaumala HP 4. Malakheti HP
5. Pabera SHP 6. Sahajpur SHP
7. Baliya SHP
Group II
Jhapa
1.Dhulawari HP 2. Baniyani HP
3. Damak HP 4. Kumarkhod HP
5. Budhabare SHP 6. Topgachhi SHP
7. Gauradaha SHP
Sarlahi
1. Gangapur HP 2. Jamunia HP
6
3. Sisautia HP 4. Sasapur HP
5. Pipariya SHP 6. Khutauna SHP
7. Kaudena SHP
7
Kanchanpur
1. Shreepur HP 2. Jimua HP
3. Parasan HP 4. Daiji HP
5. Kalika SHP 6. Gulariya SHP
7. Laxmipur SHP
Group III
Siraha
1. Khirauna HP 2. Nayanpur HP
3. Golbazar HP 4. Malahaniya HP
5. Madar SHP 6. Chandraudayapur SHP
7. Sukhchaina SHP
Chitwan
1. Khairhani HP 2. Bharatpur HP
3. Shardanagar HP 4. Shivanagar HP
5. Gunjanagar SHP 6. Divyanagar SHP
7. Shaktikhor SHP
Bardiya
1. Shorahawa HP 2. Bagnaha HP
3. Nyaulapur HP 4. Magargadhi HP
5. Kalika SHP 6. Thakurdwara SHP
7. Thothari SHP
Prescribing, Patient Care and Facility Indicators were
applied in health institutions.
For assessment of prescribing practices, prescribing as well
as patient care WHO indicators were used.
In average, 30 encounters per health unit were collected for
Prescribing Indicators. For Patient Care Indicators ten
encounters per health unit were observed and recorded.In
addition, Facility Indicators were used to assess the drug
availability and impartial information (Table -1)
4.2 Instruments
8
For collecting data on prescribing practices; Patient care
form, Encounter form and Facility forms were developed.
Structured questionnaire was developed to assess prescriber
knowledge during post test only.
All the developed instruments were field-tested in one health
post of Bhaktapur district and modified.
4.3 Intervention Strategy and Implementation
Group I was assigned intervention strategy one ie Training.
This group was designed to receive training for prescribers
from UNICEF on SDTS focusing 5-6 common health problems.
Group II was assigned Intervention strategy two ie
supervision and monitoring with feedback .
Group III was control group ie without intervention.
Intervention strategy one ie training to prescribers by
UNICEF could not take place.
Health posts and subhealth posts prescribers in Group II
received first on-site supervision and monitoring visits by
DHO/DPHO one month after base line data collection. The
second visit was two months later. During each visit DHO/DPHO
evaluated the prescribing practices using
supervision/monitoring tools and the results were immediately
fedback to the prescribers. In the second
supervision/monitoring, DHO/DPHO were provided with data from
the first supervision/monitoring for comparative feedback.
The guidelines and tools were developed by a Research Team
and field-tested in one of the health posts of Bhaktapur
district.
DHO/DPHOs, were oriented to supervision/monitoring tools by
investigators and they were also given guidelines on how to
use tools and give feedback. The tools included the same WHO
indicators, simplified by the Research Team (see Annex).
Group three health posts and sub health posts being control
9
received no intervention.
4.4. Recruitment, Orientation and Supervision of Survey Team
The survey was conducted by six teams. Each Team comprised
of two research assistants, and one supervisor, the
investigator. Research assistants were either MBBS students
or Bachelor or Master in Public Health students. The research
assistants were oriented to instruments andinvolved in field
testing.
The baseline data was collected in October,1994 and the final
data in May, 1995.
7
Table : I Health Facilities Encounters, Tracer Diagnosis, Tracer Conditions
and Drug Prescribed in Study Districts
Morang Dhanusha Kailali Jhapa Sarlahi Kanchanpur Siraha Chitwan Bardiya
Pre Post Pre Post Pre Post Pre Post Pre Post Pre Post Pre Post Pre Post Pre Post
test test test test test test test test test test test test test test test test test test
Number of Health
Facility
7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7
Encounter 210 209 210 210 211 200 216 217 210 213 214 205 210 210 211 210 210 210
Total Drug Prescribed 476 456 536 458 417 449 484 561 469 384 466 386 492 476 361 459 436 371
Consultation Time
Encounter
70 70 71 70 70 70 70 70 70 70 70 70 70 70 70 69 70 70
Dispensing Time
Encounter
70 70 66 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70
Tracer Dignosis 81 63 81 129 99 109 62 78 58 111 96 26 113 141 71 103 137 141
Tracer Condition 27 36 32 48 56 49 35 42 29 34 34 28 34 70 33 65 34 40
8
9
4.5 Secondary Coding
Collected data were coded based on knowledge and practices.
The coding for practices were grouped into indicators among
WHO Indicators of Prescribing, Patient care and Facility
indicators.
Prescribing Indicators
1 Average Number of Drugs Per Encounter - Average
calculated by dividing the total number of
different drug products prescribed, by the number of
encounters surveyed.
2 Percentage of Drugs Prescribed by Generic Name -
Percentage, calculated by dividing the number of drugs
prescribed by generic name by the total number of drugs
prescribed, multiplied by hundred.
3 Percentage of Encounter With an Antibiotic Prescribed -
Percentage, calculated by dividing the number of patient
encounters during which an antibiotic is prescribed, by
total number of encounters surveyed, multiplied by
hundred.
4 Percentage of Encounters With an Injection Prescribed -
Percentage, calculated by dividing the number of patient
encounters during which an injection is prescribed, by
the total number of encounters surveyed, multiplied by
hundred.
5 Percentage of Drugs Prescribed From Essential Drug List
-Percentage, calculated by dividing the number of
products prescribed which are listed on the essential
drug list, by the total number of products prescribed,
multiplied by hundred.
6 Average consultation time - Average, calculated by
dividing the total time for the series of consultations,
10
by the number of consultation.
7 Percentage of Drugs Actually Dispensed - Percentage,
calculated by dividing the number of drugs actually
dispensed at the health facility by the total number of
drugs prescribed, multiplied by hundred.
11
8 Availability of Key Drugs - Percentage, Calculated by
dividing the number of specified products actually in
stock by the total number of drugs on the check list
(ORS, cotrimoxazole tablet, paracetamol tablet,
mebendazole tablet,tetracycline eye ointment, ferrous
sulphate+folic acid tablet, antacid tablet, amoxycillin
capsule, procaine penicillin and benzyl benzoate)
multiplied by hundred.
9 Availability of Copy of Essential Drug Lists - Yes or
No per facility.
10 Availability of Copy of SDTS - Yes or no per facility.
11 Availability of any Other Impartial Information -
Percentage, calculated as the number of facilities where
a listed source of impartial information is present,
divided by the number of facilities surveyed.
12 Prescription in Accordance with Treatment Guidelines -
Percentage, calculated by dividing the number of cases
receiving the chosen treatment divided by the total
number of tracer diagnosis reviewed, multiplied by
hundred. In this study accepted chosen treatment means
only correct drugs and not the correct doses and
duration for single diagnosis.
13 Adequate Examination - Percentage, calculated by
dividing the number of cases who received an examination
meeting minimum criteria for adequacy for important
tracer conditions (e.g. Diarrhoea, ARI, scabies,
hyperacidity/ PUS, conjunctivitis, and anaemia) divided
by the total number of cases reviewed, multiplied by
hundred.
12
Prescribing Knowledge
Diarrhoea
1. History Taking - was defined correct based on either /or
thirst and urination.
2. Adequate Examination - was defined adequate based on
examination of skin elasticity and tongue or fontanelle
in children.
3. Drug Use - was defined correct based on Ringer lactate
use in severe dehydration.
ARI
1. History Taking - was defined correct based on fever and
duration of cough or breast sucking.
2. Adequate Examination - was defined adequate based on
counting respiration rate and chest indrawing or noisy
breathing.
3. Drug Use - was defined correct based on use of PPF or
Benzyl Penicillin or Amoxycillin.
Peptic Ulcer
1 History Taking - was defined correct based on either/or
relationship of pain with food and onset of pain.
2. Adequate Examination - was defined adequate based on
palpation of epigastrium.
3. Drug Use - was defined correct based on use of Aluminum+
Magnesium Antacids.
Anaemia
13
1. History Taking - was defined correct based on patient
history relating cause.
2. Adequate Examination - was defined adequate based on
inverting eyelid or examining tongue and examination of
nails.
Scabies
1. History Taking - was defined correct based on history of
itching.
2. Adequate Examination - was defined adequate based on
inspection of infected area or itching spots.
Conjunctivitis
1. History Taking - was defined correct based on duration
of illness
2. Adequate Examination - was defined adequate based on
inverting eye lid.
Ascariasis
Drug Use - was defined correct based on use of
piperazine.
UTI
Drug Use - was defined correct based on use of
cotrimoxazole.
14
Referral
1. UTI:
Referral - was defined appropriate based on
recurrent UTI or ineffective treatment.
2. Rheumatic Fever
Referral - was defined appropriate based on heart
complication or ineffective treatment.
4.6 Data Analysis
The data were entered into Lotus 123 and Excel and checked
manually several times for accuracy. Some of the data were
analysed manually also. The t-test and paired t-test were
used to compare the changes within the facility as well as
study groups.
If significant difference was not observed between groups, a
non-parametric test (X2 test) was applied to measure the
change. The level of significant difference was stated at 95%
confidence limit.
15
RESULTS
5. PRESCRIBING PRACTICES (Table 2 -3 and Annexe)
5.1 Percentage of Prescriptions Inaccordance with SDTS
There has been a decrease by 5.5% in intervention I, an
increase by 13.6% in intervention II and a decrease by 6.8%
in control.
There is significant increase in prescribing inaccordance
with SDTS with supervision/monitoring (df = 36, P< 0.1, t=
1.97).
The decrease in intervention I is not significant (t=-0.15).
There has been an increase in 39% of health institutions in
intervention I, 74% in intervention II and 42% in control.
Applying X2-test;
There is significant increase with supervision/monitoring
(df = 1, P < 0.05, X2 = 3.89).
In intervention I, there is no significant increase
(X2 = 0.04).
5.2 Percentage of Encounter with an injection Prescribed.
There has been an increase by 8.8% in a intervention I, a
decreased by 5.3% in intervention II and an increase by 4.3%
in control.
There is a decrease with supervision/monitoring but it is not
significant (t= -1.3).
There is an increase in intervention I but it is not
significant (t = 0.34).
There has been a decrease in 14% of health institutions in
intervention I, 43% in intervention II and 14% in control.
16
Applying X2- test;
There is significant decrease with supervision/monitoring
(P < 0.05, X2 = 4.2).
In intervention I, there is no significant decrease (X2 =0).
5.3 Average Consultation Time
There has been a decrease by 22 seconds in intervention I, an
increase by 20 seconds in intervention II and a decrease by
71 seconds in control.
There is significant increase in consultation time with
supervision/monitoring (df = 40, P < 0.01, t = 3.43, highly
significant).
The decrease in intervention I is not significant.
There has been an increase in 24% of health institutions in
intervention I, 48% in intervention II and 33% in control.
Applying X2- test;
There is no significant increase in intervention I (X2=0.47).
5.4 Percentage of Encounter with an Antibiotic Prescribed
There has been a decrease by 4.1% in intervention I, a
decrease by 12.5% in intervention II and a decrease by 5.6%
in control.
There is a decrease with supervision/monitoring but is not
significant (t= -1.38).
There is also a decrease in intervention I and is also not
significant (t = 0.66)
There has been a decrease in 38% of health institutions in
intervention I, 67% both in intervention II and control.
17
Applying X2 -test;
There is no significant decrease with supervision/monitoring
and intervention I as well.
5.5 Average number of drugs Prescribed
There has been a decrease by 0.1 in intervention I, and
intervention II but an increase by 0.1 in control.
There is a decrease with supervision/monitoring but is not
significant (t = 0).
There is also a decrease in intervention I and is also not
significant (t = -0.76)
There has been a decrease in 48% of health institutions in
intervention I, 57% in intervention II and 38% in control.
Applying X2 - test;
There is no significant decrease with supervision/monitoring
and intervention I as well.
5.6 Percentage of Drug Prescribed by Generic Name.
There has been a decrease by 3.2% in intervention I, a
decrease by 9.5% in intervention II and an increase by 4% in
control.
There has been an increase in 43% of health institutions in
intervention I, 19% in intervention II and 52% in control.
5.7 Percentage of Drugs Prescribed on EDL
There has been an increase by 1% in intervention I, a
decrease by 2.8% in intervention II and an increase by 0.2%
in control.
18
There has been an increase in 33% of health institutions in
intervention I, 52% in intervention II and 43% in control.
Applying X2- test;
There is no significant increase with supervision/
monitoring.
5.8 Percentage of Drugs Actually Dispensed
There has been a decrease by 6% in intervention I, a decrease
by 7.7% in intervention II but an increase by 3.1% in
control.
There has been an increase in 38% of health institutions in
all groups.
5.9 Percentage of Cases with an Adequate Examination
There has been an increase by 30.5% in intervention I, an
increase by 13.7% in intervention II and an increase by 9.1%
in control.
There is no significant increase with supervision/ monitoring
(t =0.22).
There is no significant increase in intervention I (t=1.69).
There has been an increase in 75% of health institutions in
intervention I, 57% in intervention II and 43% in control.
Applying X2- test;
There is significant increase in intervention I (X2 =4.36,
P<0.05) but there is no significant increase with
supervision/monitoring (X2 = 0.86) .
5.10 Percentage of Availability of Key Drugs
19
The availability of key drugs was found slightly increased
from 70 to 74 % in intervention I, slightly decreased (69 to
66%) in intervention II and decreased from 72% to 62% in
control group.
5.11 Availability of EDL, SDTS AND other Impartial
Information
The availability of Essential drug list was found increased
both in intervention I and II, where as decreased in control
group. It was increased from 10% to 14% in intervention I, 5%
to 19% in intervention II and decreased from 5% to 0% in
control.
The availability of SDTS was found increased from 0 to 5% in
intervention II where as decreased in both intervention I and
control group from 5% to 0% .
The availability of other impartial information (which
included Where there is no Doctor, CIMS; TB. Leprosy, ARI and
Diarrhoea treatment manuals; FCHV, MCHW, and TBA Manuals)
increased in Intervention I whereas decreased in both
intervention II and control group.
6. PRESCRIBING KNOWLEDGE
6.1 Diarrhoea
The knowledge of history taking was correct in 81% of
intervention I, and 71 % of both intervention II and control.
The knowledge of adequate examination was 86% of control and
intervention II, and 81% of intervention I.
The knowledge on drug use was correct in 86%, 76% and 57 % of
control, intervention I and intervention II respectively.
20
6.2 ARI
The knowledge of history taking was correct in 52%, 47% and
28% of control, intervention I and II respectively.
The knowledge of adequate examination was 38% both of control
and intervention II, and 52% of intervention I.
The knowledge on drug use was correct in 24% of control and
52% both of intervention I and II.
6.3 Peptic Ulcer
The knowledge of history taking was correct in 67%,81% and
47% of control,intervention I and II respectively.
The knowledge of adequate examination was 38%, 47% and 52% of
control, intervention I and II respectively.
The knowledge on drug use was correct in 33%, 38% and 28% in
control, intervention I and II respectively.
19
Table : 2
Prescribing Indicators
Control-Interventions
Group I Group II Group III Control Vs Control Vs
Intervention I Intervention II Control Intervention I Intervention II
Pre Post Pre Post Pre Post `t'-test X2-test `t'-test X2-
test
test test test test test test
Number of Facility 21 21 21 21 21 21 - - - -
1 Percentage of reviewed cases in 26.8 21.3 26.9 40.5 29.9 23.1 -0.15 0.04 1.97 3.89
accordance with Standard Drug
Treatment Schedule
2 Percentage of encounters with an
Injection prescribed
9 17.8 20 14.7 12.2 16.5 0.34 0 -1.3 4.2
3 Average consultation time 2'45'' 2'23'' 2'01'' 2'21'' 3'12'' 2'01'' 1.27 0.47 3.43 -
4 Percentage of encounters with an
Antibiotic prescribed
53.4 49.3 57.7 45.2 54.2 48.6 0.66 3.44 -1.38 0
5 Average number of Drugs 2.3 2.2 2.2 2.1 2 2.1 -0.76 0.44 0 1.52
Prescribed
20
21
Table : 3
Prescribing Indicators
Control-Interventions
Group I Group II Group III
Intervention I Intervention II Control
Pre-t Post Pre Post Pre Post
test test test test test test
Number of Facility 21 21 21 21 21 21
1 Percentage of drug prescribed 49.4 46.2 56 46.5 45.4 45.8
by Generic names
2 Percentage of drugs prescribed 81.7 82.7 85.7 82.9 87.9 88.1
on Essential Drugs
3 Percentage of Drugs actually 79.4 73.4 83.2 75.5 79.1 82.2
Dispensed
4 Percentage of reviewed cases 30.4 60.9 45.9 59.6 38.6 46.7
with an Adequate Examination.
5 Percentage of availability of key 69.5 73.8 68.6 66.2 71.9 61.5
Drugs
6 Availability of Essential Drug
List
9.5 14.2 4.8 19 4.8 0
7 Availbility of Standard Drug 4.8 0 0 4.8 4.8 0
Treatment Schedule
8 Percentage of Impartial 33 47.6 28.6 19 23.8 9.5
20
21
6.4 Anaemia
The knowledge of history taking was correct in 28%, 57% and
9% of control, intervention I and II respectively.
The knowledge of adequate examination was 100%, 95% and 85%
of control, intervention I and II respectively.
6.5 Scabies
The knowledge of history taking was correct in 85% both of
control, and intervention I and 62% of intervention II.
The knowledge of adequate examination was 86%, 91% and 81% of
control, intervention I and II respectively.
6.6 Conjunctivitis
The knowledge of history taking was correct in 38% both of
control, and intervention I and only 9% of intervention II.
The knowledge of adequate examination was 100% in control and
intervention I and 76% of intervention II .
6.7 Ascariasis
The knowledge on drug use was correct in 33%, 19% and 47% of
control, intervention I and II respectively.
6.8 UTI
The knowledge on drug use was correct in 76%, 43% and 47% of
control, intervention I and II respectively.
6.9 Referral
22
The knowledge on referral for UTI was appropriate in 57%
both of control, intervention I and only 33% of intervention
II.
The knowledge on referral for Rheumatic Fever was appropriate
in 57%, 43% and 19% of control, intervention I and II
respectively.
23
CONCLUSION
The research has found significant increase in consultation time
and prescriptions in accordance with Standard Drug Treatment
Schedule (SDTS) and significant decrease in injection encounter
with supervision/ monitoring.
Other prescribing indicators eg antibiotic encounter, average
number of drug prescribed, and drugs prescribed on Essential Drug
List (EDL), also have shown improvement with supervision/
monitoring, though not significant.
On the other hand, a few indicators eg prescription by generic,
cases with adequate examination, and drugs actually dispensed, did
not indicate improvement with supervision/monitoring which might
have been affected by other factors eg knowledge and drug supply .
Recommendations
. Implement supervision/monitoring and feedback for
improving use of SDTS in health institutions.
. Implement the strategy ie supervision/monitoring to
improve rational prescribing in health institutions.
. Supervision/monitoring is feasible with existing
structure in the District Health Office with some
motivation and orientation to DHO/DPHO. During study
DHOs expressed great satisfaction in using indicators as
it provided them opportunity to see the quality of
service. The motivation will have great impact to
improve rational prescribing in HP and SHP reducing the
drug cost in the district.
. Supervision/monitoring should be implemented in a few
districts initially as a pilot project .
24
. The facilities which perform most poorly eg 30% or more,
less than district average for any indicator should get
supervision/monitoring focussed on that specific
indicator.
REFERENCES
1. Kafle, K.K; Pradhan, Y.M.S; Shrestha, A.D; Karkee, S.B; :
Drug Use in PHC facilities of Kathmandu. J.INST. MED, 14,
NO.4, 318-326, 1992.
2. Kafle, K.K; Pradhan, Y.M.S; Shrestha, A.D; Karkee, S.B;
:INRUD Drug Use Indicators in Nepal: practice pattern in
health posts in four districts. INRUD News, Vol. 3, No.1,
1992.
3. Quick, J; Laing, R; Ross, Degnan D; : Intervention research
to promote clinically effective and economically efficient
use of Pharmaceuticals: International Network for Rational
Use of Drugs (INRUD). J.of Clinical Epidemiology, 44 supp 11,
pp 578-668, 1991.
4. Action Programme on Essential Drugs: How to Investigate Drug
Use in Health Facilities: WHO/DAP, 1993.
5. Hogerzeil, H, V; Bimo; Ross-Degnan, D; Laing, R.O; et al :
Field tests for Rational Drug Use in twelve developing
Countries. The Lancet, 342 (1), 1408- 1410, 1993.
1
Prescribing Indicators Annexe: 1 Morang
No Health Facility T.Sinuwari HP Haraicha HP Dadarbairiya HP Bayarban HP Sanischare SHP Nocha SHP Pathari SHP
Pre Post `t' Pre Post `t' Pre Post `t' Pre Post `t' Pre Post `t' Pre Post `t' Pre Post `t'
test test value test test value test test value test test value test test value test test value test test value
1 Average number of drugs prescribed 2.2 2.2 ns 2.2 2.8 ns 2.5 2.1 ns 2.5 2.3 ns 2 1.4 ns 1.8 2.2 ns 2.3 2.7 ns
2 Percentage of drug prescribed by
Generic names
58.7 49.2 ns 58.2 50.6 ns 32.9 51.6 s 57.5 22.1 s 47.6 53.5 ns 52.8 56.9 ns 70.1 46.3 s
3 Percentage of encounters with an Antibiotic
prescribed
58.6 58.6 ns 63.3 63.3 ns 53.6 53.3 ns 69 53.3 ns 43.3 46.7 ns 40 43.3 ns 70.6 66.8 ns
4 Percentage of encounters with an 0 20.7 - 40 36.7 ns 3.6 23.3 s 0 6.7 - 0 10 - 16.7 0 - 0 0 -
Injection prescribed
5 Percentage of drugs prescribed on Essential
drugs
87.3 76.9 ns 89.6 79.5 ns 81.4 81.3 ns 69.9 79.4 ns 93.4 93 ns 100 100 ns 76.6 95 s
6 Average consultation time 1'19'' 1'25'' ns 2'36'' 1'13'' ns 2'41'' 2'15'' ns 1'18'' 4'12'' ns 1'30'' 1'16'' ns 1'40'' 1'27'' ns 3'32'' 4'24'' ns
7 Percentage of drugs actually 66.7 66.2 ns 83.6 71.1 ns 84.3 68.8 ns 90.4 54.4 s 75.4 93 s 96.2 98.5 ns 96.1 92.5 ns
Dispensed
8 Percentage of availability of key 80 100 - 100 80 - 100 60 - 70 50 - 70 80 - 80 70 - 70 80 -
indicator drugs
9 Percentage of reviewed cases 50 66.7 ns 60 100 ns 28.6 57.1 ns - 14.3 - 16.7 0 - 77.8 0 - 20 50 ns
with an adequate examination.
10 Percentage of reviewed cases in 33.3 25 ns 25 28.6 ns 9.1 - - 6.7 - - 33.3 46.7 ns 40.9 0 - 0 13.3 -
accordance with Standard Drug
Treatment Schedule
11 Availability of Essential Drug List 0 0 - 0 1 - 1 0 - 0 1 - 0 0 - 1 0 - 0 0 -
12 Availbility of Standard drug 0 0 - 0 0 - 0 0 - 0 0 - 0 0 - 0 0 - 0 0 -
Treatment Schedule
13 Availability of other impartial 1 1 - 1 1 - 1 1 - 1 1 - 0 0 - 0 0 - 0 0 -
Information
s = Significant ns = Not significant
2
3
Prescribing Indicators
Annexe :2 Dhanusa
No Health Facility Sinurjora HP Ghodghas HP Dhalkabar HP Parbaha HP Bhuichakarpur SHP Shapahi HP Batteshwor SHP
Pre Post `t' Pre Post `t' Pre Post `t' Pre Post `t' Pre Post `t' Pre Post `t' Pre Post `t'
test test value test test value test test value test test value test test value test test value test test value
1 Average number of drugs prescribed 2.5 2.2 ns 3 1.6 ns 2.5 3.2 ns 2.9 1.7 ns 1.1 2 ns 3 2 ns 2.8 2.5 ns
2 Percentage of drug prescribed by generic names
60.8 57.8 ns 44 40.4 ns 72 50 s 57.5 57.6 ns 72.7 56.7 ns 18.7 55.7 s 35.3 13.3 s
3 Percentage of encounters with an
antibiotic prescribed
40 46.7 ns 63.3 40 ns 56.7 66.7 ns 70 56.7 ns 13.3 23.3 ns 80 53.3 s 50 63.3 ns
4 Percentage of encounters with an 6.7 6.7 ns 6.7 3.3 ns 46.7 50 ns 13.3 30 ns 0 3.3 - 26.7 23.3 ns 3.3 3.3 ns
injection prescribed
5 Percentage of drugs prescribed 85.1 82.1 ns 64.8 87.2 s 93.3 72.9 s 66.7 84.6 s 100 91.7 s 68.1 90.2 s 82.4 53.3 s
on essential drugs
6 Average consultation time 5'26'' 2'12'' ns 4'11'' 2'13'' ns 3'25'' 1'34'' ns 3'13'' 1'41'' ns 2'41'' 1'49'' ns 3'35'' 1'56'' ns 3'13'' 2'10'' ns
7 Percentage of drugs actually dispensed 85.1 86.6 ns 64.8 87.2 s 89.3 63.5 s 60.9 88.5 s 100 70 s 55 62.3 ns 58.8 33.3 s
8 Percentage of availability of key
indicator drugs
100 70 - 60 90 - 100 80 - 60 100 - 60 50 - 60 50 - 70 30 -
9 Percentage of reviewed cases 0 83.3 - 80 57.1 ns 28.6 77.8 ns 33.3 66.7 ns 0 57.1 - 33.3 85.7 s 0 83.3 -
with an adequate examination.
10 Percentage of reviewed cases in 25 23.1 ns 21.4 42.1 ns 5.6 15.4 ns 50 28 ns 44.4 4.4 s - 33.3 - 0 0 -
accordance with Standard drug
treatment schedule
11 Availability of essential drug list 0 0 - 0 0 - 0 0 - 0 0 - 0 0 - 0 0 - 0 0 -
12 Availbility of Standard drug 0 0 - 0 0 - 0 0 - 0 0 - 0 0 - 0 0 - 0 0 -
treatment schedule
13 Availability of other impartial information 0 0 - 0 0 - 0 1 - 1 1 - 0 0 - 0 0 - 0 1 -
s = Significant
ns = Not significant
4
Prescribing Indicators
Annexe: 3
Kailali
No Health Facility Pahalmanpur HP Malakheti HP Chaumala HP Basauti HP Sahajpur SHP Baliya SHP Pavera SHP
Pre Post `t' Pre Post `t' Pre Post `t' Pre Post `t' Pre Post `t' Pre Post `t' Pre Post `t'
test test value test test value test test value test test value test test value test test value test test value
1 Average number of drugs prescribed 2.6 2.4 ns 2.6 2.8 ns 2.2 2.1 ns 2.1 2.2 ns 1.3 1.9 ns 1.9 2.2 ns 2 1.2 ns
2 Percentage of drug prescribed by generic
names
38.5 42.7 ns 44.7 45.7 ns 44.8 43.8 ns 59.7 47.7 ns 33.3 50 ns 51.7 65.1 ns 43.3 29.7 ns
3 Percentage of encounters with an antibiotic
prescribed
50 45.2 ns 41.4 48.3 ns 22.6 56.7 s 50 50 ns 6.3 15 ns 26.7 37.9 ns 60 20 s
4 Percentage of encounters with an injection
prescribed
3.3 22.6 s 3.5 13.8 ns 16.1 26.7 ns 3.3 23.3 s 0 0 - 6.7 12.2 ns 40 0 -
5 Percentage of drugs prescribed on essential
drugs
61.5 76 s 86.8 79 ns 91 70.3 s 87.1 63.2 s 100 100 ns 96.6 92.1 ns 88.3 100 s
6 Average consultation time 2'08'' 2'38'' ns 2'17'' 3'06'' ns 4'08'' 1'51'' ns 2'07'' 3'18'' ns 3'10'' 1'56'' ns 2'27'' 1'04'' ns 3'30'' 3'36'' ns
7 Percentage of drugs actually dispensed 74.4 86.7 ns 100 92.6 s 94 51.6 s 95.2 96.9 ns 100 97.4 ns 84.5 96.8 s 98.3 97.3 ns
8 Percentage of availability of key indicator
drugs
40 50 - 60 90 - 90 70 - 40 80 - 60 70 - 60 90 - 80 60 -
9 Percentage of reviewed cases 33.3 100 s 40 33.3 ns 20 33.3 ns 16.7 90 s 0 14.3 - 60 80 ns 33.3 33.3 ns
with an adequate examination.
10 Percentage of reviewed cases in 5.6 20 ns 0 0 - 15.8 8.3 ns 70 17.7 s 53.3 33.3 ns 36.4 11.8 ns 13.3 66.7 s
accordance with Standard drug
treatment schedule
11 Availability of essential drug list 0 0 - 1 0 - 0 0 - 0 0 - 0 0 - 0 0 - 0 0 -
12 Availbility of Standard drug 0 0 - 1 0 - 0 0 - 0 0 - 0 0 - 0 0 - 0 0 -
treatment schedule
13 Availability of other impartial 0 0 - 0 1 - 1 1 - 1 1 - 0 0 - 0 0 - 0 0 -
information
s = significant
ns = not significant
5
6
Prescribing Indicators
Annexe: 4 Jhapa
No Health Facility Damak HP Baniyani HP Dhulabari HP Kumarkhod HP Budhabare SHP Gauradaha SHP Topgachhi SHP
Pre Post `t' Pre Post `t' Pre Post `t' Pre Post `t' Pre Post `t' Pre Post `t' Pre Post `t'
test test value test test value test test value test test value test test value test test value test test value
1 Average number of drugs prescribed 1.3 2.6 ns 2.7 2.6 ns 2.6 3.1 ns 2.5 2.8 ns 2.5 3.4 ns 1.7 1.8 ns 2.2 1.9 ns
2 Percentage of drug prescribed by generic
names
67.5 29.4 s 67.1 58.4 ns 60.3 6.5 s 42.1 35.7 ns 26.8 9.8 s 23.1 41.8 s 68.9 55.2 ns
3 Percentage of encounters with an antibiotic
prescribed
19.4 44.4 s 83.3 83.3 ns 66.7 50 ns 83.3 66.7 ns 80 36.7 s 74.2 63.3 ns 76.5 25.8 s
4 Percentage of encounters with an injection
prescribed
0 2.8 - 63.3 13.3 s 6.7 3.3 ns 36.7 46.7 ns 20 13.3 ns 0 6.7 - 0 0 -
5 Percentage of drugs prescribed on essential
drugs
80 72.8 s 90.2 89.6 ns 84.6 57 s 85.5 83.3 ns 70.7 43.1 s 98.1 74.6 s 98.7 89.7 s
6 Average consultation time 3'30'' 2'0'' ns 1'49'' 1'27'' ns 1'23'' 2'42'' ns 2'37'' 4'12'' ns 2'51'' 5'02'' ns 2'30'' 1'41'' ns 2'33'' 5'10'' ns
7 Percentage of drugs actually dispensed 82.5 54.4 s 89 79.2 ns 68 47.3 s 85.5 64.3 s 40.2 28.4 ns 92.3 45.5 s 98.7 91.4 ns
8 Percentage of availability of key indicator
drugs
50 60 - 60 50 - 60 30 - 90 60 - 70 60 - 70 40 - 70 70 -
9 Percentage of reviewed cases 60 20 ns 50 0 - 50 83.3 ns 50 16.7 ns 60 20 ns 85.7 100 ns 50 0 -
with an adequate examination.
10 Percentage of reviewed cases in 70 50 ns 0 33.3 - 10 12.5 ns 0 11.1 - 0 0 - 100 18.2 s 14.3 43.5 ns
accordance with Standard drug
treatment schedule
11 Availability of essential drug list 1 0 - 0 1 - 0 1 - 0 0 - 0 0 - 0 0 - 0 0 -
12 Availbility of Standard drug 0 0 - 0 1 - 0 0 - 0 0 - 0 0 - 0 0 - 0 0 -
treatment schedule
13 Availability of other impartial information 1 0 - 0 0 - 1 1 - 1 1 - 0 0 - 0 0 - 0 0 -
s = significant
ns = not significant
7
8
Prescribing Indicators
Sarlahi
Annexe: 5
No Health Facility Jamuniya HP Sasapur HP Ganga Pur HP Sisautiya HP Piparia SHP Kaudena SHP Khutauna SHP
Pre Post `t' Pre Post `t' Pre Post `t' Pre Post `t' Pre Post `t' Pre Post `t' Pre Post `t'
test test value test test value test test value test test value test test value test test value test test value
1 Average number of drugs prescribed 2.9 2.1 ns 2.6 1.8 ns 2.1 2.5 ns 1.9 2.2 ns 2 1.4 ns 1.8 1.4 ns 2.3 1.2 ns
2 Percentage of drug prescribed by generic
names
72.7 71.2 ns 62.4 49.1 ns 76.6 60.5 ns 79 68.2 s 66 63.4 ns 66 69.8 ns 20.3 89.2 s
3 Percentage of encounters with an antibiotic
prescribed
63.3 50 ns 75.8 43.3 s 53.3 70 ns 53.3 53.3 ns 85.2 26.7 s 30 19.4 ns 36.7 23.3 ns
4 Percentage of encounters with an 56.7 43.8 ns 51.5 0 - 33.3 43.3 ns 0 40 - 81.5 3.3 s 0 0 - 3.3 0 -
injection prescribed
5 Percentage of drugs prescribed on essential
drugs
93.2 98.5 ns 83.5 80 ns 85.9 85.5 ns 63.2 81.8 ns 96.2 100 ns 86.8 100 s 76.8 94.6 s
6 Average consultation time 2'01'' 1'54'' ns 1'42'' 1'48'' ns 1'16'' 2'19'' ns 1'18'' 2'23'' ns 1'35'' 1'59'' ns 1'59'' 2'11'' ns 1'43'' 2'14'' ns
7 Percentage of drugs actually dispensed 85.2 95.5 s 69.4 98.2 s 82.8 85.5 ns 87.7 93.9 ns 96.2 95.1 ns 81.1 97.7 s 60.9 78.4 ns
8 Percentage of availability of key 90 70 - 90 80 - 80 90 - 50 80 - 60 70 - 50 60 - 60 30 -
indicator drugs
9 Percentage of reviewed cases 50 100 s 50 75 ns 0 60 - 75 100 ns 0 100 - 75 100 ns 80 100 ns
with an adequate examination.
10 Percentage of reviewed cases in 0 41.7 - 50 60 ns 50 28.6 ns 0 30 - 0 47.4 - 0 68.2 - 16.7 68.4 s
accordance with Standard drug
treatment schedule
11 Availability of essential drug list 0 0 - 0 0 - 0 0 - 0 1 - 0 0 - 0 1 - 0 0 -
12 Availbility of Standard drug treatment
schedule
0 0 - 0 0 - 0 0 - 0 0 - 0 0 - 0 1 - 0 0 -
13 Availability of other impartial information 1 1 - 1 0 - 1 0 - 0 0 - 0 0 - 0 1 - 0 0 -
s = significant
ns = not significant
9
Prescribing Indicators
Kanchanpur
Annexe: 6
No Health Facility Jimuwa HP Daiji HP Parasan HP Shree Pur HP Laxmi Pur SHP Kalika SHP Gularia SHP
Pre Post `t' Pre Post `t' Pre Post `t' Pre Post `t' Pre Post `t' Pre Post `t' Pre Post `t'
test test value test test value test test value test test value test test value test test value test test value
1 Average number of drugs prescribed 2.2 2 ns 1.6 2 ns 2.1 2.1 ns 2.5 1.9 ns 2 1.7 ns 2.2 1.8 ns 2.6 1.7 ns
2 Percentage of drug prescribed by generic
names
73.5 42.4 s 44.7 65.6 ns 55.9 56.3 ns 45.5 60 ns 57.4 37.3 s 59.1 49 ns 45.6 34 ns
3 Percentage of encounters with an antibiotic
prescribed
64.5 33.3 s 26.7 56.7 s 59.4 46.7 ns 61.3 63 ns 60 36.7 ns 16.7 32.1 ns 40 26.7 ns
4 Percentage of encounters with an 12.9 13.3 ns 3.3 10 ns 21.9 16.7 ns 29 18.5 ns 6.7 26.7 ns 0 3.6 - 0 3.3 -
injection prescribed
5 Percentage of drugs prescribed on essential
drugs
92.7 93.2 ns 91.5 95.1 ns 85.3 90.6 ns 77.9 90 ns 73.8 92.2 s 100 100 ns 86.1 92 ns
6 Average consultation time 2'16'' 1'47'' ns 1'54'' 1'52'' ns 2'22'' 1'50'' ns 1'48'' 2'15'' ns 2'05'' 1'31'' ns 1'52'' 1'50'' ns 1'25'' 1'11'' ns
7 Percentage of drugs actually dispensed 100 88.1 s 100 88.5 s 88.2 87.5 ns 75.3 76 ns 91.8 84.3 ns 100 84.3 s 93.7 98 ns
8 Percentage of availability of key indicator
drugs
80 80 - 80 80 - 70 100 - 60 70 - 80 60 - 60 70 - 60 80 -
9 Percentage of reviewed cases 33.3 0 - 10 50 ns 66.7 40 ns 33.3 100 s 16.7 100 s 33.3 20 ns 66.7 57.1 ns
with an adequate examination.
10 Percentage of reviewed cases in 57.9 - - 52.9 66.7 ns 27.3 42.9 ns 22.2 50 ns 16.7 40 ns - 0 - 15.4 0 -
accordance with Standard drug
treatment schedule
11 Availability of essential drug list 0 0 - 0 0 - 0 0 - 0 0 - 0 0 - 0 0 - 0 0 -
12 Availbility of Standard drug 0 0 - 0 0 - 0 0 - 0 0 - 0 0 - 0 0 - 0 0 -
treatment schedule
13 Availability of other impartial information 1 0 - 0 0 - 0 0 - 0 0 - 0 0 - 0 0 - 0 0 -
s = significant
10
ns = not significant
Prescribing Indicators
Siraha
Annexe: 7
No Health Facility Khirauna HP Gol Bazar HP Nayanpur HP Malahaniya HP Sukhachaina SHP Madar SHP Chandra Ud. SHP
Pre Post `t' Pre Post `t' Pre Post `t' Pre Post `t' Pre Post `t' Pre Post `t' Pre Post `t'
test test value test test value test test value test test value test test value test test value test test value
1 Average number of drugs prescribed 1.8 1.7 ns 2.5 2 ns 3.2 3.3 ns 3.8 2.9 ns 2 2.4 ns 1.6 1.8 ns 1.5 1.7 ns
2 Percentage of drug prescribed by generic
names
61.8 48.1 ns 50 19.7 s 24 38.8 s 33.3 27.6 ns 48.3 54.8 ns 61.7 58.2 ns 47.7 58 s
3 Percentage of encounters with an antibiotic
prescribed
26.7 46.7 ns 76.7 26.7 s 60 53.3 ns 66.7 43.3 ns 66.7 10 s 3.3 13.3 ns 56.7 33.3 ns
4 Percentage of encounters with an injection
prescribed
3.3 0 - 33.3 0 - 6.7 23.3 ns 10 3.3 ns 0 10 - 0 0 - 0 3.3 -
5 Percentage of drugs prescribed 89.1 80.8 ns 93.4 95.1 ns 76 70.4 ns 82.5 73.6 ns 96.7 100 ns 97.9 94.6 ns 100 98 ns
on essential drugs
6 Average consultation time 1'46'' 2'29'' ns 3'04'' 3'20'' ns 3'06'' 1'56'' ns 2'50'' 3'15'' ns 2'52'' 2'0'' ns 1'46'' 3'06'' ns 2'25'' 2'12'' ns
7 Percentage of drugs actually dispensed 89.1 94.2 ns 76.3 78.7 ns 59.4 49 ns 63.2 46 s 100 98.6 ns 97.9 89.1 ns 100 94 ns
8 Percentage of availability of key indicator
drugs
80 70 - 70 70 - 90 60 - 60 30 - 70 80 - 70 70 - 70 60 -
9 Percentage of reviewed cases 50 90 ns 33.3 30 ns 33.3 100 s 75 50 ns 20 100 s 0 80 - 0 40 -
with an adequate examination.
10 Percentage of reviewed cases in accordance
with Standard drug treatment schedule
45.5 47.1 ns 5.9 52.9 s 0 4.8 - 11.1 14.3 ns 13.3 3.6 ns 30 31.3 ns 80 47.6 s
11 Availability of essential drug list 0 0 - 0 0 - 0 0 - 0 0 - 0 0 - 0 0 - 0 0 -
12 Availbility of Standard drug 0 0 - 0 0 - 0 0 - 0 0 - 0 0 - 0 0 - 0 0 -
treatment schedule
13 Availability of other impartial information 0 0 - 0 0 - 1 0 - 1 1 - 0 0 - 0 0 - 0 0 -
s = significant
11
ns = not significant
Prescribing Indicators
Annexe: 8 Chitawan
No Health Facility Shardanagar HP Khairahani HP Bharatpur HP Shivanagar HP Gunjnagar SHP Shaktikhor SHP Divyanagar SHP
Pre Post `t' Pre Post `t' Pre Post `t' Pre Post `t' Pre Post `t' Pre Post `t' Pre Post `t'
test test value test test value test test value test test value test test value test test value test test value
1 Average number of drugs prescribed 1.7 2.2 ns 1.8 2.2 ns 1.6 2.3 ns 1.5 2.1 ns 1.8 2 ns 1.8 1.9 ns 1.8 2.5 ns
2 Percentage of drug prescribed by generic
names
36.5 56.7 s 70 37.3 s 72.9 30.4 s 51.1 31.3 s 32.7 59 s 43.9 64.9 s 53.7 52.7 ns
3 Percentage of encounters with an antibiotic
prescribed
63.3 60 ns 78.6 60 ns 54.8 36.7 ns 46.7 76.7 s 43.3 76.7 s 56.3 63.3 ns 66.7 63.3 ns
4 Percentage of encounters with an injection
prescribed
16.7 16.7 ns 25 36.7 ns 41.9 6.7 s 16.7 23.3 ns 3.3 30 s 12.5 33.3 s 26.7 33.3 ns
5 Percentage of drugs prescribed 86.5 82.1 ns 98 82.1 s 95.8 85.5 s 97.8 70.3 s 76.4 93.4 s 89.5 98.3 s 96.3 94.6 ns
on essential drugs
6 Average consultation time 2'31'' 1'44'' ns 1'38'' 1'47'' ns 2'33'' 2'42'' ns 1'45'' 2'03'' ns 2'45'' 2'07'' ns 1'45'' 1'22'' ns 3'25'' 2'37'' ns
7 Percentage of drugs actually dispensed 90.7 88.1 ns 98 80.6 s 87.5 87 ns 97.8 67.2 s 76.4 96.7 s 100 96.5 ns 98.2 96 ns
8 Percentage of availability of key indicator
drugs
90 90 - 80 80 - 90 90 - 90 90 - 80 40 - 90 80 - 90 80 -
9 Percentage of reviewed cases 66.7 0 - 40 33.3 ns 66.7 22.2 ns 40 40 ns 100 60 s 40 30 ns 60 10 s
with an adequate examination.
10 Percentage of reviewed cases in accordance
with Standard drug treatment schedule
45.5 28.3 ns 28.6 29.4 ns 33.3 7.1 s - 13.3 - 28.4 20 ns - 23.5 - 66.7 11.1 s
11 Availability of essential drug list 0 0 - 0 0 - 1 0 - 1 1 - 0 0 - 0 0 - 0 0 -
12 Availbility of Standard drug 0 0 - 0 0 - 0 0 - 1 1 - 0 0 - 0 0 - 0 0 -
treatment schedule
13 Availability of other impartial information 1 0 - 0 0 - 1 0 - 1 1 - 0 0 - 0 0 - 0 0 -
12
s = significant
ns = not significant
13
Prescribing Indicators Bardiya
Annexe: 9
No Health Facility Bagnaha HP Nyaulapur HP Sorahawa HP Magargadhi HP Dhodhari SHP Thakurdwara SHP Kalika SHP
Pre Post `t' Pre Post `t' Pre Post `t' Pre Post `t' Pre Post `t' Pre Post `t' Pre Post `t'
test test value test test value test test value test test value test test value test test value test test value
1 Average number of drugs prescribed 2.8 1.8 ns 2.3 1.7 ns 2.6 1.7 ns 1.6 2.2 ns 1.7 1.7 ns 1.8 1.6 ns 1.8 1.6 ns
2 Percentage of drug prescribed by Generic
names
48.2 76.4 s 28.6 41.2 ns 37.1 37.3 ns 67.3 40 s 40 34.6 ns 35.8 47.9 ns 52.8 67.4 ns
3 Percentage of encounters with an 86.7 73.3 ns 63.3 36.7 s 56.7 33.3 ns 53.3 50 ns 36.7 56.7 ns 53.3 40 ns 23.3 66.7 s
Antibiotic prescribed
4 Percentage of encounters with an 16.7 46.7 ns 16.7 20 ns 3.3 16.7 ns 0 6.7 - 10 0 - 10 13.3 ns 3.3 23.3 s
Injection prescribed
5 Percentage of drugs prescribed 86.7 94.6 ns 64.3 98 s 89.7 90.2 ns 95.9 81.5 s 94 100 ns 94.3 91.7 ns 98.1 100 ns
on Essential drugs
6 Average consultation time 6'30'' 0'23'' ns 4'48'' 1'34'' ns 5'18'' 1'39'' ns 4'42'' 1'32'' ns 5'0'' 1'22'' ns 3'54'' 1'50'' ns 5'24'' 1'25'' ns
7 Percentage of drugs actually dispensed 49.4 89.1 s 62.9 88.2 s 56.4 90.2 ns 83.7 63.1 s 74 98.1 s 77.4 79.2 ns 94.3 100 ns
8 Percentage of availability of key 50 60 - 40 50 - 60 30 - 50 80 - 80 50 - 60 70 - 50 60 -
indicator drugs
9 Percentage of reviewed cases 60 0 - 0 33.3 - 50 66.7 ns 0 66.7 - 33.3 80 ns 0 14.3 - 42.9 42.9 ns
with an adequate examination.
10 Percentage of reviewed cases in accordance
with Standard Drug Treatment Schedule
0 28.6 - 12.5 30.8 ns 4.6 22.7 ns 25.9 14.3 ns 52.2 25 s 38.1 16.7 ns 30 23.5 ns
11 Availability of essential drug list 0 0 - 0 0 - 0 0 - 0 0 - 0 0 - 0 0 - 0 0 -
12 Availbility of Standard Drug 0 0 - 0 0 - 0 0 - 0 0 - 0 0 - 0 0 - 0 0 -
Treatment Schedule
13 Availability of other impartial information 0 1 - 0 0 - 0 0 - 0 1 - 0 0 - 0 0 - 0 0 -
s = significant
ns = not significant
1
Annexe: 10
Control Intervention
I (%)
Intervention
II (%)
Diarrhoea
History taking
Examination
Drug use
71.4
85.7
85.7
80.9
80.9
76.2
71.4
85.7
57.2
ARI
History taking
Examination
Drug use
52.4
38.1
23.8
47.6
52.4
52.4
28.6
38.1
52.4
Peptic Ulcer
History taking
Examination
Drug use
66.7
38.1
33.3
80.9
47.6
38.1
47.6
52.4
28.6
Anaemia
History taking
Examination
28.6
100.0
57.1
95.2
9.5
85.7
Scabies
History taking
Examination
85.7
85.7
85.7
95.5
61.9
81.0
Conjunctivitis
History taking
Examination
38.1
100.0
36.1
100.0
9.5
76.2
Ascariasis
Drug use
33.3
19.0
47.6
UTI
Drug use
76.2
42.9
47.6
2
Referral
UTI
Rheumatic fever
57.1
57.1
57.1
42.9
33.3
19.1
Annexe: 11
QUESTIONNAIRE
Name of Health Worker: ................... Post:...............
HP/SHP:................... District:...........
Interviewer:.................. Date:...............
Instruction: Put tick [ ] or specify the first response (Do not
prompt).
1. Which drug you think, should be prescribed for severe
dehydration ?
[ ] ORS [ ] Normal Saline
[ ] Dextrose Saline [ ] Ringers Lactate
[ ] Others (specify) [ ] Don't Know
2. Which drug you think, should be prescribed for
Ascariasis ?
[ ] Piperazine [ ] Mebendazole
[ ] Albendazole [ ] Pyrental Pamoate
[ ] Other (specify) [ ] Don't Know
3. Which drug you think, should be prescribed for UTI ?
3
[ ] Nitrofurantoin [ ] Nalidixic Acid
[ ] Cotrimoxazole [ ] Tetracycline
[ ] Other (specify) [ ] Don't Know
4. Which drug you think, should be prescribed for
Pneumonia?
[ ] PPF [ ] Benzyl Penicillin
[ ] Tetracycline [ ] Amoxycilin
[ ] Other (specify) [ ] Don't Know
5. Which drug you think, should be prescribed for Peptic
Ulcer ?
[ ] Aluminiun+ Magnesium Antacid
[ ] Sodium bicarbonate
[ ] Aluminum Hydroxide
[ ] Other (specify) [ ] Don't Know
Instruction: Put the tick [ ] or specify more than one answer.
6. In your opinion, what should be examined to diagnose a
case of dehydration ?
[ ] Skin elasticity [ ] Pulse
[ ] Inspection of Tongue
[ ] Examining Frontanalle in children
[ ] Other (specify) [ ] Don't Know.
7. In your opinion, what should be examined to diagnose a
case of ARI ?
4
[ ] Respiration Rate [ ] Chest Indrawing
[ ] Cyanosis [ ] Noisy Breathing
[ ] Other (specify) [ ] Don't Know
8. In your opinion, what should be examined to diagnose a
case of Anaemia ?
[ ] Inverted Eyelid [ ] Tongue
[ ] Nails [ ] Blood Investigation
[ ] Other (specify) [ ] Don't Know
9. In your opinion, what should be examined to diagnose a
case of Scabies ?
[ ] Inspection of Infected Area
[ ] Itching Spots
[ ] Other (specify) [ ] Don't Know
10. In your opinion, what should be examined to diagnose a
case of Conjunctivitis ?
[ ] Inverted Eyelid
[ ] Inspection of Eye with Torch light
[ ] Other (specify) [ ] Don't Know
11. In your opinion, what should be examined to diagnose a
case of Peptic Ulcer ?
[ ] Epigastrium [ ] Whole Abdomen
[ ] Other (specify) [ ] Don't Know
12. In your opinion, what history should be taken to find
5
out seveirity of diarrhoea ?
[ ] Frequency of Loose Motion [ ] Vomiting
[ ] Thirst [ ] Urination
[ ] Other (specify) [ ] Don't Know
13. In your opinion, what history should be taken to
diagnose a case of ARI ?
[ ] Duration of Cough [ ] Breast Sucking
[ ] Fever [ ] Other (specify)
[ ] Don't Know
14. In your opinion, what history should be taken to
diagnose a case of Anaemia ?
[ ] History of illness [ ] Duration
[ ] Other (specify) [ ] Don't Know
15. In your opinion, what history should be taken to
diagnose a case of Scabies ?
[ ] Duration [ ] Time of Itching
[ ] Itching [ ] Family History
[ ] Other (specify) [ ] Don't Know
6
16. In your opinion, what history should be taken to
diagnose a case of Conjunctivitis ?
[ ] Duration [ ] Itching
[ ] Other (specify) [ ] Don't Know
17. In your opinion, what history should be taken to
diagnose a case of Peptic Ulcer ?
[ ] Pain relation with Food
[ ] Onset of Pain [ ] Appetite
[ ] Site of Pain
[ ] Other (specify) [ ] Don't Know
18. In your opinion, when should a case of UTI be referred?
[ ] Recurrent UTI [ ] Ineffective Treatment
[ ] All Patients [ ] Children
[ ] Other (specify) [ ] Don't Know
19. In your opinion, when should a case of Rheumatic fever
be referred ?
[ ] Heart Complication [ ] Ineffective Treatment
[ ] All Patients [ ] Children
[ ] Other (specify) [ ] Don't Know
Annexe: 12
Supervision/Monitoring Form
7
PRESCRIBING INDICATOR
#
Patient Identifier
(Name)
Consulting
time
(Min)
Adequate exam
Problems 0/1
1
2
3
4
5
6
7
8
9
10
Case count (#)
Sum
Average
Percent of exam
Ilaka/Subhealth Post ............... District: ............
Supervisor: ....................... Date: ................
8
Annexe: 13 Supervision/Monitoring Form
ENCOUNTER FORM
# Patient Indicator
(Name)
Age
Sex
Prescriber Date
Health
Problems Health Problem Discription/Diagnosis
1
2
3
Prescription Character Patient drug knowledge Label
Drugs name, strength and
dose
Dispensed
Quantity
When
(0/1)
How
much (0/1)
Knowl
edge
(0/1)
Patient
name
(0/1)
Drug
name (0/1)
when
(0/1)
1
Drugs 2
3
4
5
6
7
8
9
10
Ilika/Sub Health Post: ...... District: .......
Private Dispenser :........ Date: ........
Supervision: ...........
9
Annexe: 14
Supervision/Monitoring Form
ENCOUNTER SUMMARY FORM
#
# Drugs
Prescription
Antibiotics
(0/1)
Injectio
ns (0/1)
#
Generics
#
on EDL
#
Drug
Dispensed
Standard
Treatment
(0/1)
1
2
3
4
5
6
7
8
9
10
Case
count
Sum
Average
Percent of encounters of
encounters
Of total
drugs
of total
drugs
of total
drugs
of diagnosis
Ilaka/Subhealth Post ............... District: ............
Supervisor: ....................... Date: ................
10