Introduction To The Zone

Why Do We Gain Weight, Get Sick,

and Age Faster?

Overview of Anti-Inflammatory Nutrition

Unique Roles For Each Dietary Intervention

• Zone Diet

– Reduction of insulin resistance

• Omega-3 Fatty Acids

– Reduction of inflammation

• Polyphenols

– Slowing of the aging process

What is the Zone?

Benefits of Being In The Zone

• Permanent weight control

• Treating chronic disease

• Better physical performance

• Thinking fast

• Better emotional control

• Slow down the aging process

Consequences of Being Out of the Zone

• Gain weight

• Get sick

• Age faster

It’s Really A Genetic Transformation Zone:

You Can Change Your Future By Changing the Expression of Your

Genetic Code

The Science Behind The Zone

• Improved hormonal control

• Control of gene transcription factors

• Resolution of inflammation

• Changes in epigenetics

Three Stages of Disease

Wellness

Cellular Inflammation

Chronic Disease

Food As A Drug

Food

Macronutrients(Carbohydrates, Proteins, Fat)

Hormonal Response(Insulin, Glucagon, Eicosanoids)

The Best Way To Reach the Zone Is

Through The Zone Diet

High-Carbohydrate Diets

Excess Insulin Production

Fat Accumulation

Zone

Insulin Balance

Loss of Inflammatory Fat

Low-Carbohydrate/High Protein

Diets

Excess Glucagon Production

Cortisol Increase

The Zone Diet is Based Upon on The Balance of the Protein-to-Glycemic Load

Protein-to-Glycemic Load Ratio

Zone Diet Recommendations (1995)

• 40% low-glycemic load carbs

• 30% low-fat protein

• 30% monounsaturated fat

• 1,200 to 1,500 calories per day

Dietary Guidelines From The Joslin Diabetes Research Center At Harvard (2007)

• 40% low glycemic load carbs

•

• 20-30% low-fat protein

• 30-40% monounsaturated fat

• 1,200 to 1,500 calories per day

Per Cent Calories Can Be Deceiving on 40-30-30 Dietary Balance

Macronutrient 1,200 calories/day 1,500 calories/day

Carbohydrate 120 g/day 150 g/day

Protein 90 g/day 112 g/day

Fat 40 g/day 50 g/day

Zone Diet: An Anti-Inflammatory Diet

Key Aspects:

• Based on the glycemic load

• Balance of protein, carbohydrates, and fat

What’s Driving Physician Interest:

• Diet without hunger

• Flexibility

• Moderate approach

Implications:

• Long-term compliance

• Medically validated

How Difficult Is To Follow The Zone Diet?

Start With:

Low-Fat Protein

Balance With:

ColorfulCarbohydrates

Low-Fat Protein

Add Fat!

Good Choices Low in Omega-6 and

Saturated Fats

Extremely Bad Choices

High in Omega-6 Fats

Vegetables

Fruits

Low-fat Protein

Monounsaturated Fat

Grains and Starches(Use in Moderation)

Zone Food Pyramid

The Zone Diet Is the Evolution of the Mediterranean Diet

• It’s Mediterranean ingredients with the Zone blueprint for hormonal balance

• The more white you put on the plate, the more inflammation you create

Anti-Inflammatory Supplements to the Anti-Inflammatory

Zone Diet:

Fish Oil and Polyphenols

Omega-3 Fatty Acids:

Putting Our the Inflammatory Fire

Clinical Benefits of High-Dose Fish Oil

• Heart Disease

• Cancer

• Depression

• Attention Deficit Disorder

• Multiple Sclerosis

• Brain Trauma

• Alzheimer’s

• Chronic Pain

• Osteoporosis

• Skin Disorders

• Fertility

• Fat Loss

How Much Omega-3 Fats Do You Need?

Maintain Wellness 2.5 g/day

Treat Obesity, Diabetes, and CHD 5 g/day

Treat Chronic Pain 7.5 g/day

Treat Neurological Disease >10 g/day

Why Not Just Eat More Fish?

• Lobster: 6 lbs. per day

• Tuna: 2 lbs. per day

• Salmon: 1/3 lb. per day

The Solution

• Purified omega-3 fatty acid concentrations

• Purity is a must

Polyphenols:

The Color of Anti-Inflammation Nutrition

Mechanisms of Action

• Anti-oxidants

• Anti-inflammatory

• Aging-aging

How Many Polyphenols Do You Need Every Day?

Different Effects At Different Levels

Low Levels (0.5 g/day): Anti-oxidants • Reduction of free radicals

Intermediate Levels (1.0 g/day): Anti-inflammatory• Cardiovascular benefits

High Levels (1.5 g/day): Anti-aging• Slow down rate of aging

• Think faster

Typical Sources Providing1 gram of Polyphenols

• 1 kg of vegetables

• 500 g of berries

• 12 glasses of red wine, 120 glasses of white wine, or 120 bottles of vodka

• 500 ml of extra virgin olive oil

The Solution

• Purified polyphenol extracts

• Purity is a must

Why Anti-Inflammatory Nutrition Is Important

Cellular Inflammation

Obesity

Diabetes

Alzheimer’s