Introduction

Utah P41 Renewal Site Visit 2015

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Schedule

Introduction

Center Strategy

Introduction

Center History

Center for Bioelectric Field Modeling, Simulation and Visualization established in 1999.

Renewed as the Center for Integrative Biomedical Computing (CIBC) established in October 2005.

Submitted Renewal in September 2009 (end date is July 31, 2010)

Renewed until July 31, 2015 Center Moves to NIGMS in 2012New Program Officer – Fred FriedmanCenter Renewal Proposal – September 25, 2014Center Renewal Site Visit – February 18, 2015

Introduction

Center Impact

NIH/NCRR CenterAwarded for 3 years.

Sept, 1999

NIH/NCRR CenterRenewal for 3 years.

Sept, 2002

NIH/NCRR CIBCRenewal for 5 years

Feb. 2005

NIH/NCRR CIBCRenewal for 5 years,

July 2010 2015

46 PublicationsFirst Workshopmap3d v3.0 - 6.2BioPSE/SCIRun v1.0.0 - v1.6.0

49 PublicationsSecond Workshopmap3d v6.4 - 6.5BioPSE/SCIRun v1.20.0First release:

BioFEMBioTensorBioImage

159 Publications5 WorkshopsBioPSE/SCIRun v1.20.0 - v4.2

BioFEMBioTensorBioImageNew BioMesh3D

map3d v6.4 - 6.5ImageVis3D v1.0Seg3D v1.12ShapeWorks

132 Publications13 WorkshopsNIH/BTR PortalBioPSE/SCIRun v4.2 - v4.7SCIRun v5.0 alpha

BioMesh3DBioMesh3D Client v1.0BrainStimulatorForward/Inverse Toolkit

map3d v7.1ImageVis3D v2.0.1 - v3.1Seg3D v2.15ShapeWorks v0.3.0 - v1.2Cleaver v2.0

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Research Impact

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Software – Downloads >165,000

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Software Wikipedia Pages

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Software Videos

http://vimeo.com/85177018

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CIBC Software Development

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Training Impact: Since 2005Postdoctoral Fellows:• Jeroen Sinstra—Research Staff Scientist, Numira Biosciences, Inc.

• Xavier Tricoche—Associate Professor, Computer Science, Purdue University

• Jens Krueger—Professor of Computing Science, University of Duisberg

• Josh Levine—Assistant Professor of Computing Science, Clemson University

• Erik Anderson—Research Scientist, EGI

Graduate Students—Ph.D.:• Seok Lew—Massachusetts General Hospital, Dept. of Radiology• Fangxiang Jiao – TGS• Burak Erem – Postdoc, Boston Children’s Hospital• Suyash Awaite - Assistant Professor in the Department of Computer Science and Engineering at the

Indian Institute of Technology, Bombay.• Dafang Wang – Post Doctoral Fellow, Johns Hopkins University• Sarah Geneser—Post Doctoral Fellow, Stanford University• Alireza Ghodrati—Biomedian LLC• Saeed Babaeizadeh—Phillips Medical• Miriah Meyer—Post Doctoral Fellow, Harvard University, Assistant Professor of Computer Science and

SCI Institute• Jason Shepherd—Sandia National Laboratory• Chris Butson—Associate Professor, University of Utah• Sila Kurugol - Postdoc at BWH• Josh Cates—Research Staff CARMA• Darrell Swenson – L3

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Training Impact (Cont.)

Graduate Students—M.S.:• Anastasia Mironova—Conoco Phillips• Lee Roy Myers—Instructor, Eastern Wyoming College• P.J. Hawkes—Medical School, University of Utah• J.R. Blackham—Apple Computer• Andrew Keely—Nuance Communications• Jaume Coll Font – Ph.D. student at NEU (CIBC Supported)

Undergraduate Students:• McKay Davis—Makai Ocean Engineering, Waimanalo, Hawaii

• Zachary Warnock—Medical School, University of Utah

• Lindsey Healy—Graduate Student, Bioengineering, Univ. of Utah

• Patrick Rasch

• Anatoliy Zharkikh

• Cory Shirts

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Summary of Center Impact Assessment

- Technology development/algorithms• Papers published• Citations to papers

- Software/dissemination• New software products• Software releases• Downloads and citations/acknowledgements

- Scientific Impact• Scientific results from DBPs (enabled by TRD)• Training- Graduate students/fellows- Tutorials and workshops

- Mechanisms- Weekly CIBC Executive Meetings- Weekly Software Design and Evaluation Meetings

- Annual External Advisory Board Meetings

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Center Vision

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Center Vision

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Center Vision

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Biomedical Research Clusters

IntroductionDriving Biological Partners

Microscopy and Small Scale Imaging: Rai Winslow, PhD, John’s Hopkins University,

Microscopy and Small Scale Imaging: Gabrielle Kardon, PhD, University of Utah,

Biomechanics and Blood Flow: Alison Marsden, PhD, University of California, San Diego,

Biomechanics and Blood Flow: Jeffrey Weiss PhD, Andrew Anderson PhD, University of Utah, Statistical and Biomechanical Analysis of Hip Dysplasia

IntroductionDriving Biological Partners

Neuromodulation and Brain Source Localization, Don Tucker, PhD, University of Oregon and EGI

Neuromodulation and Brain Source Localization, Michael Okun, MD and Kelly Foote, MD, University of Florida

Cardiac Arrhythmias and Ischemia: Natalia Trayanova, PhD, John’s Hopkins University, Simulation of Cardiac Defibrillation

Cardiac Arrhythmias and Ischemia: Nassir Marrouche MD, University of Utah, Image-based Management of Atrial Fibrillation

Introduction

Center Impact

SINCE OUR LAST RENEWAL IN 2009:

Software Impact

• Over 15,000 downloads of SCIRun, (all from outside the Center and our affiliate institutions)

• Over 15,000 downloads of Seg3D,

• Over 7000 downloads of the CIBC data sets.

• Over 23,800 downloads of ImageVis3D and ImageVis3D Mobile.

(Average 250% increase in software downloads)

Publication Impact

• Over 300 papers published by scientists outside the Center referencing CIBC software (33% increase)

• Center members have authored over 140 publications related to biomedical computing in a wide range of technical and biomedical journals and conference proceedings.

NIH/NIGMS CIBC Renewal, 2009 2015

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Schedule