ISN NEWS 58 August 2016 INSIDE THIS ISSUE CKD: Closing the gaps in patient care globally Advancing Nephrology Around the World 03 ISN Membership survey 2016 - what you told us 04 ISN CKD ‘Closing the Gaps’ initiative The global burden of CKD: a call for serious action 06 ISN Global Kidney Health Summit Pressing for CKD awareness on a global scale 08 ISN Programs Sharing knowledge across borders 10 ISN Affiliated and Collective Societies update Introducing the Georgian nephrology community 12 Hydration for Kidney Health (H4KH) Hydration and kidney health today 13 ISN Membership update Northern Light Discovery Portal and Kidney International Reports 14 ISN-American Nephrologists of Indian Origin (ANIO) Innovative online training in nephropathology 15 ISN upcoming events WCN 2017 - early registration and abstracts submission open AN OFFICIAL PUBLICATION OF THE INTERNATIONAL SOCIETY OF NEPHROLOGY
Transcript
ISN NEWS 58 August 2016
INSIDE THIS ISSUE
CKD: Closing the gaps in patient care globally
Advancing Nephrology Around the World
03 ISN Membership survey 2016 - what you told us
04 ISN CKD ‘Closing the Gaps’ initiative
The global burden of CKD: a call for serious
action
06 ISN Global Kidney Health Summit Pressing for CKD awareness
on a global scale
08 ISN Programs Sharing knowledge across borders
10 ISN Affi liated and Collective Societies update
Introducing the Georgian nephrology
community
12 Hydration for Kidney Health (H4KH) Hydration and kidney health today
13 ISN Membership update Northern Light Discovery Portal and Kidney
International Reports
14 ISN-American Nephrologists of Indian Origin (ANIO)Innovative online training in nephropathology
15 ISN upcoming events WCN 2017 - early registration and abstracts
submission open
AN OFFICIAL PUBLICATION OF THE INTERNATIONAL SOCIETY OF NEPHROLOGY
It is time to take action
This edition of ISN News highlights one of two major initiatives that fi t with our overall mission
of advancing nephrology worldwide.
The ISN CKD ‘Closing the Gaps’ initiative hopes to provide a comprehensive strategy to
address issues related to Chronic Kidney Disease (CKD) care delivery worldwide. The strategy
involves international leaders to understand and address issues related to gaps in clinical
care delivery, research and advocacy.
The ISN ‘Closing the Gaps’ initiative complements the ISN 0by25 project, which aims to
eliminate preventable deaths from Acute Kidney Injury (AKI) worldwide by 2025. Several of
the projects that make up this initiative are moving forward and we hope to share more of
the results in the coming months.
Although renal replacement therapy has been available for decades in high-income countries,
relatively little is known about the optimal way to coordinate, fi nance and regulate the care
for people with CKD throughout the spectrum (from diagnosis, care and access to renal
replacement therapies). Throughout the world inequalities exist within emerging countries as
well as in wealthier countries.
We hope that the following pages inspire you to raise more awareness about this growing
Education Ambassador Program – Vivekanand Jha (India)
Fellowship Committee – Allison Eddy (Canada)
Clinical Research Committee – Marcello Tonelli (Canada)
Sister Renal Centers Program Committee – Paul Harden (UK)
ISN Regional Board Chairs Africa Regional Board – Mohammed Benghanem Gharbi (Morocco)
North and East Asia Regional Board – Minghui Zhao (China)
Eastern and Central Europe Regional Board – Rumeyza Kazancioglu
(Turkey)
Latin America Regional Board – Ezequiel Bellorin Font (Venezuela)
Middle East Regional Board – Mona Alrukhaimi (United Arab Emirates)
Oceania & South-East Asia Regional Board – Peter Kerr (Australia)
NIS and Russia Regional Board – Alexandr Zemchenkov (Russia),
Irma Tchokhonelidze (Georgia)
South Asia Regional Board – Vivekanand Jha (India),
Harun Ur Rashid (Bangladesh)
Western Europe & North America Regional Board – Eric Rondeau
(France), Jeff Perl (Canada)
ISN Initiatives & Committee Chairs Research Portfolio Director – Marcello Tonelli (Canada)
Global Education Portfolio Director – David Harris (Australia)
Advocacy Portfolio Director – Robyn Langham (Australia)
0by25 – Ravindra Mehta (USA)
Closing the Gaps – Adeera Levin (Canada)
ISN-ACT - Vlado Perkovic (Australia)
ISN Meetings Committee – Carol Pollock (Australia)
Education Committee – Vivekanand Jha (India)
ISN-ANIO India Committee – John Feehally (United Kingdom),
Prabir Roy-Chaudhury (USA)
Publications Committee – Bertram Kasiske (USA),
Tazeen Jafar (Singapore)
Renal Disaster Relief Task Force – Wim Van Biesen (Belgium)
Saving Young Lives Committee – John Feehally (United Kingdom)
World Kidney Day Steering Committee – Philip Li (Hong Kong),
Guillermo Garcia Garcia (Mexico)
ISN News
Published by ISN
Staff Editor: Sally Horspool
ISN Executive Director: Luca Segantini
The contents of this publication are
compiled in good faith. The publisher
accepts no responsibility for omissions
or errors.
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ISN Membership - make a differenceISN connects science and humanitarian efforts. Through education, ISN is reaching out
to global medical communities, giving them the knowledge and support to reduce the
impact of kidney disease worldwide. Membership to ISN supports these activities and
provides member specifi c benefi ts including exclusive eligibility for ISN capacity building
programs, online and print subscription to Kidney International, online training and
education, and reduced registration fees to ISN events.
Membership is now free for trainees.
Not yet a member? Visit: www.theisn.org/join
Update your membership and profi le
To ensure you receive all your benefi ts,
please keep your profi le up to date and
renew your membership in a timely manner.
Access or update your profi le at:
www.theisn.org/memberlogin
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ISN survey 2016- what you told usWe are delighted to share with you the outcome of the membership survey 2016. Responses from more than 500 members have helped us understand what you enjoy most about ISN and how you wish to contribute to our activities in the future. See the full results of the membership survey displayed with infographics here:www.theisn.org/membership
Thank you to all who completed the ISN membership survey. You have helped us donate $5,000 to the World Kidney Fund. Five lucky respondents also got a free ISN membership.
CKD patients are more likely to die, mostly from premature cardiovascular
disease, than survive to the point of needing dialysis. There are about
2.2 million people receiving dialysis globally (projected to be 5.4 million by
2030). An independent risk factor for infection, hospitalizations,
cardiovascular diseases, and cancer, CKD has pervasive and permanent
implications on patients’ identities, employment, relationships, and lifestyles.
The ISN ‘Closing the Gaps’ initiative complements the ISN 0by25 project,
which aims to eliminate preventable deaths from Acute Kidney Injury (AKI)
worldwide by 2025. It is made up of several sub-projects, including the
ISN Global Kidney Health Atlas (GKHA), ISN Global Kidney Health Summit,
the ISN Global Kidney Policy Forum and The Lancet Kidney Campaign.
According to David Johnson, who is leading the GKHA with Aminu Bello:
“We don’t have a good handle on the burden of CKD or how health
structures around the world deal with the disease.”
THE GLOBAL BURDEN OF CKD: a call for serious actionChronic Kidney Disease (CKD) affects approximately 10% of the adult population, worldwide.
While the distribution of those receiving and not getting renal replacement therapies (dialysis and transplantation), varies by country, the incidence and prevalence of CKD are remarkably consistent globally, though not always well documented.
ISN’s latest endeavor, the ISN ‘Closing the Gaps’ initiative sets out to defi ne the global needs and the current state of CKD care, and create a ’blueprint’ for more balanced CKD care globally, through more research, education and advocacy.
“We don’t have a good handle on the burden of
CKD or how health structures around the world deal with
the disease.”
David Johnson
For the latest information on any of the projects that are part of this initiative, visit:
ISN News 58 | August 20164
How is CKD treated worldwide?There are renal registries in many but not all developed countries.
They are mainly concerned with end-stage renal disease (dialysis/
transplantation), few countries have registries of people with CKD
at earlier stages, and many do not provide publicly accessible
reports. This leaves critical gaps in knowledge of prevalence and
incidence of CKD, which would help in healthcare planning for CKD
patients globally.
Aminu Bello explains how the team behind the Global Kidney Health
Atlas (GKHA) is collecting information and will collate it along the
principles of the Universal Healthcare Coverage. “We want to create
a global snapshot on the current state of healthcare fi nancing and
policies, work force distribution care delivery and information systems
relevant to kidney care worldwide,” he says.
These fi rst survey results will be followed by a second phase that
gathers data on relevant CKD epidemiology (risk factors, burden
and outcomes) across countries and regions.
The GKHA builds on the work of a previous ISN initiative, Kidney
Health for Life (KH4L), which was a limited CKD multinational
inventory in Western Europe, Canada and Israel. GKHA will create
a systematic data repository using the ISN infrastructure of Regional
Boards and Affi liated Societies, to summarize the structure, format
and outcomes in all regions of the world.
The objective is to come up with a high-level overview of the current
state of kidney care (CKD and AKI) and look at how it is organized
and structured worldwide. It also aims to outline a comparative
analysis and data synthesis of the trends in the burden of CKD and
its attendant consequences across the world.
Finally, it will become a platform for championing the cause of CKD
using the identifi ed gaps modeled on UHC domains and build the
foundation for a global CKD care surveillance network.
THE GLOBAL KIDNEY HEALTH ATLAS SURVEY
The data for the GKHA was collated via an online
questionnaire-based survey (administered in English,
French and Spanish), and grey literature review of reports
published by major international agencies such as the
World Health Organization, the United Nations, the World
Bank and the Organisation for Economic Co-operation and
Development (OECD).
The survey was targeted at national nephrology societies,
policymakers, consumer organizations such as kidney
foundations, patient organizations and advocacy groups
across 126 countries. The information on each country
was provided by at least three stakeholders across the
10 ISN regions.
CONTINUING TO RAISE AWARENESS
The Lancet Kidney Campaign is continuing to be a source
of monthly updates on advances in nephrology as well as
expert commentaries and
interviews on key health
and policy issues relevant
to kidney disease.
It builds on ISN’s 2015 Lancet
Commission, which called for
eliminating preventable deaths
from AKI by 2025 and gathers research and analysis on
AKI, CKD, dialysis and transplantation from across the
journal’s database.
Visit: www.thelancet.com/campaigns/kidney
www.theisn.org/closingthegaps
The Lancet Kidney CampaignRaising awareness of the under-recognised burden of Kidney Disease
www.thelancet.com/campaigns/kidney
The International Society of Nephrology
5ISN News 58 | August 2016
selected group of 75 key global opinion leaders and
researchers met in Vancouver, Canada, to participate in a
unique workshop. The individuals represented the
international community, ISN committees and programs, scientists,
and policy-makers.
Chaired by ISN President Adeera Levin, Kai-Uwe Eckardt and
Marcello Tonelli, the ISN Global Kidney Health Summit’s overarching
goal is to develop a ‘blueprint’ for action to change the status of
kidney health worldwide, building on present knowledge, research
and clinical activities.
Under discussion were CKD issues of global relevance, in the context
of the ISN Global Kidney Health Atlas, the interfaces between CKD
and AKI, and the link between kidney disease and cardiovascular
and metabolic disorders.
“We hope the outcome of this summit will form the basis of one or
several publications to guide the future of care and research. We
are aiming for a Commission publication in the Lancet, to coincide
with the World Congress of Nephrology (WCN) 2017 in Mexico
City,” says ISN President Adeera Levin.
“This was the fi rst of two activities, which we anticipate will impact
policymaker decision making,” adds Levin.
The ISN Global Kidney Policy Forum, the fi rst of which will be held
prior to the World Congress of Nephrology in Mexico City 2017, is
intended to be a recurring event.
“Our goal is to hold these in various world regions, where policy
and advocacy issues, based in part on information generated from
the Summit and the Atlas, will be discussed with Ministers of Health
and World Health Organization representatives – both central and
local. The Policy Forum will involve government offi cials and clinicians,
health economists and researchers,” says Levin.
The goal is to improve the understanding of regional issues related
to delivering kidney care and its funding, highlighting and addressing
the gaps identifi ed in the ISN Global Kidney Health Atlas, and
contextualizing this within the global burden of kidney disease.
PRESSING FOR CKDAWARENESS on a global scale
A
Organized in July, the ISN Global Kidney Health Summit was the fi rst advocacy project to take place as part of the ISN ‘Closing the Gaps’ initiative.
“We hope the outcome of this
summit will form the basis of one or several publications to guide
the future of care and research.”
ISN President Adeera Levin
ISN News 58 | August 20166
www.isnforefronts.org/sandiego
ISN Forefronts Symposium 2016The Metabolome and Microbiome in Kidney DiseaseSeptember 23-25 2016San Diego (CA), USA
Advancing Nephrology Around the World
SYMPOSIA
ISN FOREFRONTS
ISN PROGRAMS sharing knowled
Inter-regional collaboration continues to be the most effective way of training medical communities globally. Centers in Swaziland and South Africa are using the ISN Sister Renal Center Programs to improve dialysis care and raise awareness about diabetes.
South African Educational Ambassador builds ties with Nigeria
In February, Ikechi Okpechi from
the University of Cape Town visited
the Usmanu Danfodiyo University Teaching
Hospital in Sokoto, Nigeria. He shared his knowledge to put
together a training course focusing on epidemiology, clinical
nephrology and renal pathology.
This visit is a prime example of collaborations taking place
globally thanks to the efforts of ISN Program participants.
The University of Cape Town is also building links with doctors
in Swaziland.
“I would recommend that other institutions with poor infra-
structure be involved in the ISN Programs as it will im-
mensely help to improve the quality of care for patients,”
says Okpechi. This collaboration also led to the development
of a Continuing Medical Education course in Sokoto, orga-
nized with the Nigerian Association of Nephrology.
In June, doctors at the
Mbabane Kidney and
Dialysis Center in
Swaziland experi-
enced their fi rst Sister
Renal Center visit.
This unit now cares
for 110 hemodialysis
patients. There are
two other dialysis
units in Swaziland with
a total of about 90 chronic
hemodialysis patients
between them.
ISN Fellow Thandi Dlamini who trained at the University of Cape
Town, now a consultant nephrologist at the center in Swaziland,
played a valuable role in introducing the University of Cape Town
and Groote Schuur hospital to the Swaziland institute.
This visit was also an opportunity to organize a workshop to
address critical issues related to hypertension and diabetes,
gathering 200 delegates including specialists, primary care prac-
titioners and nurses. As a result of this workshop the Ministry of
Health has set up a work group to amend the current national
guidelines.
“I would recommend that other institutions with
poor infrastructure be involved in the ISN Programs as it will immensely help to improve the quality of care
for patients.”
Ikechi Okpechi
Thandi Dlamini
Workshop - Swaziland
Visit to Ministry of Health - Nigeria
ISN News 58 | August 20168
ge across borders
More importantly, they give doctors access to specifi c
knowledge, become valuable networking opportunities
and help advocate about nephrology to governments
in low-and-middle income countries.
CME updateSeveral Continuing Medical Education courses have taken place since the beginning of the year. They are often the fruit of growing partnerships between ISN Program participants.
Network meeting at Ruijing Hospital Shanghai, Jiao Tong University - C
hina
Renal Technicians Update - NigeriaSi
an H
ospital in Jiaxing, Zhejing Province - China
Faculty group photo - Shanghai - China
2016
N
ephrology Update West Lake Forum
Sul
tan
of S
okot
o at
the o
pening ceremony of the annual scientifi c conference - Nig
eria
9ISN News 58 | August 2016
ISN Affi liated and Collective Societies updateWith a total of 91 Affi liated Societies, the Dialysis, Nephrology and Kidney Transplantation Union of Georgia, Syrian Society of Nephrology and Transplantation, Society of Nephrologists, Dialysis and Transplant Physicians of Kazakhstan, and National Nephrology Society of El Salvador are the latest tohave joined our growing network.
Introducing the Georgian nephrology communityThe Georgian Union of Dialysis, Nephrology and Kidney
Transplantation (DNT) was established in 2003 and so far, it remains
a unique alliance for all nephrologists in the country.
Irma Tchokhonelidze, Chair of the DNT Union, who is based at Tbilisi
State Medical University, believes that becoming an ISN Affi liated
Society means inspiration, hope and support. “It is inspiring to
become part of the global philanthropic movement against the silent
epidemic that is Chronic Kidney Disease, always be abreast of
rapidly unfolding achievements and advancements in nephrology
and have support in resolving of the local problems through advice
and help from ISN experts.”
Being part of the international renal community will strengthen
the DNT Union’s existing collaboration with the country’s
Ministry of Labor, Health and Social Affairs “Ultimately
it can change the national healthcare system’s strat-
egy for nephrology services, bringing long-term
benefi ts for patients suffering from kidney
disease,” says Tchokhonelidze.
“It is inspiring to become part of the global philanthropic
movement against the silent epidemic that is
Chronic Kidney Disease...”
Irma Tchokhonelidze, Chair of the DNT Union
Find out more, visit: www.theisn.org/about-isn/
partners-and-affi liates/affi liated-societies
ISN News 58 | August 201610
ONE GLOBAL MISSIONBuilding Kidney Health Equality
Worldwide
THEISN.ORG/PROGRAMS
Programs and application deadlines
Fellowship Apply by October 1 or May 1
Sister Renal Centers Apply or request update by October 1
Continuing Medical Education Apply 3 to 6 months before the start of the course
Clinical Research Apply by October 1 or May 1
Educational Ambassadors Apply by October 1 or May 1
Advancing Nephrology Around the World
EDUCATION, TRAINING & RESEARCH
ISN PROGRAMS
Held in the French spa town of Évian-les-Bains, the
main highlights under discussion focused on hydration
in pregnant and breastfeeding women and hydration
biomarkers and assessment.
A specific session was also dedicated to “Water regulation:
from single cells to the whole body” which gathered very well-
known speakers in the field of renal physiology and pathologies
including Prof. Dennis Brown, Dr. Lise Bankir and Prof. Vincente
Torres.
For the first time, Sofia Enhörning and Fabiana Nerbass,
winners of 2015 ISN H4KH Hydration for Kidney Health and
New Investigator grants, presented their respective projects.
Danone Nutricia Research and the ISN collaborated on creating
the Hydration for Kidney Health (H4KH) research initiative to
stimulate the interest of established and new researchers to
explore the role of hydration in kidney health.
Dr. Enhörning gave the background, design and methodology
of her project “Plasma copeptin as a predictor of, and copeptin
associated loci in, cardiorenal disease – population based
prospective cohort studies and a mendelian randomization
approach.”
While Dr. Nerbass gave a clear, concise and comprehensive
description of how her 12-month experience in the Kidney
Clinical Research Unit in London, Ontario (Canada) will enrich
and foster her project “Kidney health in Brazilian industrial
workers exposed to heat stress and dehydration.”
These talks were followed by a fruitful and enthralling discussion
on these projects and the next steps of the initiative.
Hydration and kidneyhealth today
For further information about the Hydration for Kidney
Health Initiative (H4KH), visit: www.theisn.org/h4kh
INITIATIVE
ISN H4KH
The recent Annual Hydration for Health (H4H) Scientifi c Conference was a forum for researchers worldwide to share the latest scientifi c and medical evidence around hydration.
ISN News 58 | August 201612
MEMBERSHIPupdateIn this edition, we give you the latest ISN membership news so you can stay up to date on the benefi ts of being part of our Society.
Northern Light Discovery Portal is now part of the ISN membership packageThe Northern Light ‘Discovery’ database is now freely available to
all registered ISN members. This latest benefi t will make the task
of gathering and searching for meeting abstracts more easy and
effi cient. As an extensive multidisciplinary database, it counts over
two million cutting-edge abstracts from the last four years. Where
possible, the full content of posters is also included.
Abstracts presented at Nexus and Forefronts symposia are now
available. Moreover, we also encourage participants from the recent
Nexus meeting in Berlin to upload the abstracts they presented.
Finally, to make the important link between nephrology and diabe-
tes, the database will soon feature some 8,000 posters from the
American Society of Diabetes and European Association for the
Study of Diabetes.
ISN and Elsevier announce the launch of Kidney International ReportsOn June 15, 2016, ISN and Elsevier launched Kidney International
Reports (KI Reports). This new bi-monthly, open access journal will
publish leading research and developments related to kidney disease.
The publication is designed to be a forum and a learning center for
the improved care of patients with kidney disease.
The journal will publish original clinical and select translational articles,
as well as other educational content related to the pathogenesis,
evaluation, and management of acute and chronic kidney disease,
end stage renal disease (including transplantation), acid-base, fl uid
and electrolyte disturbances, and hypertension.
Head to www.theisn.org/events/abstracts-posters-
database to access this ISN member benefi t.
13ISN News 58 | August 2016
INNOVATIVE ONLINE TRAINING in nephropathology
n countries such as India, renal pathology work is concentrated
in major academic centers. Most of these perform light and im-
munofl uorescence, but lack the ability to do routine electron
microscopy.
Centers capable of providing all three modalities are essential for
providing adequate diagnostic work and training of future genera-
tions of renal pathologists. However, establishing these centers is
expensive and associated with complex issues of laboratory man-
agement and highly-specialized technical staff training.
The year-long web-based Clinical Nephropathology Certifi cate
Program (CNC) developed by the ISN-American Nephrologists of
Indian Origin (ANIO) Committee has very successfully used a blended
structure of pre-recorded lectures, live webinars, and formative
assessments for nephrologists and pathologists worldwide.
Currently, over 200 students from more than 50 countries are involved
in this program. On satisfaction surveys, all of the participants rated
the overall course experience very highly and felt that the program
had a positive impact on their practice. The pre- and post-test
knowledge analysis during the 2014/15 course showed a 37%
improvement in test results, suggesting a signifi cant gain in knowl-
edge during this program.
Although internet connectivity and speed could be a potential chal-
lenge for physicians in low- and middle-income countries, this
educational model has a great potential to further expand and
provide much-needed nephropathology training worldwide, and
may be used as a model for other areas of nephrology, such as
dialysis and transplantation.
By providing this type of training to physicians in countries with no
or minimal nephropathology resources and promoting active and
stimulating learning, this program has greatly contributed to the
global nephrology community.
ISN-American Nephrologists of Indian Origin’s year-long web-based Clinical Nephropathology Certifi cate Program focuses on the principles and practice of nephropathology.
I
ISN News 58 | August 201614
ISN World Congress of Nephrology 2017Sustainability and Diversity
(Special focus 2017: Diabetes and Kidney Disease)
April 21-25, 2017, Mexico City, Mexico
www.wcn2017.org
ISN events connect global medical communities,giving them the knowledge and support to reducethe impact of kidney disease worldwide.
ISNupcoming events
Check out ISN Education webinarsAs well as ISN events, you can also catch the latest ISN Education webinars, visit: www.theisn.org/education
ISN Forefronts Symposium 2016The Metabolome and Microbiome in Kidney Disease
September 23-25, 2016, San Diego (CA), USA
www.isnforefronts.org/sandiegoSYMPOSIA
ISN FOREFRONTS
APRIL 21-25 - MEXICO
ISN WCN ’17
WCN 2017 – early registration and abstract submission openEarly bird registration and abstract submission are now open for the ISN World
Congress of Nephrology (WCN) in Mexico City from April 21 to 25, 2017.
For the fi rst time, an international nephrology congress focuses on diabetes and
kidney disease. A worldwide problem, but one that is very important to Latin
America and Mexico, the site of this congress.
Uniquely placed as a truly global meeting, WCN gives access to international medical
expertise in renal treatment, research and care, from bench to bedside. You will get a
genuinely-enriching and professional exchange of knowledge with world-renowned
nephrologists and endocrinologists.
The scientifi c program is complemented by novel Nephrology Biennial Review (NBR)
courses given in three languages, covering the most important research of the past two
years from various fi elds within nephrology.
You can also participate in hands-on courses on Interventional Nephrology, organized jointly
with the Brazilian Society of Nephrology, as well as lectures on renal pathology, renal
systems biology, clinical epidemiology and clinical trials, which will be given by some of the
most highly-respected peers within the fi eld, from multiple countries.
