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x AU PAT H 0 LOGY DEPARTMENT SMWT LOI iVNPYIflJfl INTRODUCTION 1 a Blood utilization monitoring isa component of our institutional PBM program. At Saint Louis University Hospital (SLUH), an academic, tertiary care facility, we perform concurrent daily blood utilization reviews. During our audit, a surprising number of single-unit plasma transfusions were identified in patients with normal coagulation values This study was performed to evaluate single-unit plasma transfusions in detail, to identify opportunities to improve transfusion practice. A total of 2,887 units of plasma were transfused in 2017. 395(14%) were single-unit transfusions; 328(11%) met the inclusion criteria. 55 single-unit transfusions were associated with INR values 1.5. Surgical subspecialties and emergency medicine were the most common transfusing services. A post-transfusion INR, when available, did not demonstrate a significant change from the pre-transfusion baseline. The most common indications for transfusion included hypovolemia and bleeding. See Results Diagram below ‘V 35 (14%) were single-unit transfusions STUDY DESIGN Data for 2017 plasma transfusions were extracted from our electronic health record system Inclusion Criteria ‘All patients were adults (>18 years old) Patients further subdivided into two groups; patients with INR values s1.5 and patients with INR values >1.5 ‘Patients with INR values 1.5 were the primary focus of this study •Additional study data collected included the transfusing clinical service, a post-transfusion INR value obtained within 24 hours of transfusion (if available), and the probable indication for transfusion Exclusion Criteria: ‘Patients transfused with plasma in the operating room or post-anesthesia care unit A daily audit revealed that single-unit plasma transfusion events are common. Surgical subspecialties and emergency medicine accounted for the majority of these transfusions. These ikely represent inappropriate transfusions and opportunities to improve practice institutionally. Though single-unit red cell and platelet transfusions represent desirabe practices, single-unit plasma transfusions are an undesirable quality improvement metric. 0 SAINT LOUIS uNIVERSITY. Focused Evaluation of Single-Unit Plasma Transfusions in a Tertiary Care Academic Medical Center Thomas Fay, M.D., Daniela Hermelin, M.D., Douglas Blackall, M.D., M.RH. Department of Pathology, Saint Louis University School of Medicine RESULTS . S -V Total of 2,887 units of plasma transfused S p it V MM CONCLUSIONS 55 single-unit transfusion, were associated vnth an INR value 1s surgical .uhspariali.n i’d em erg. n n edo ne j wentsicd as the no,, fteç,r,t on .rng prow en of vng!. FFPunns -V 328(11%) met the inclusion critnta Mail common indication, fortran, fusion included hypovolemla and bleeding
