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CH203 Lecture 1 CH203 Lecture 1 September 3, 2009 John. A. Porco, Jr. Department of Chemistry Department of Chemistry [email protected]
Transcript
Page 1: John. A. Porco, Jr.people.bu.edu/porcogrp/CH203/Lecture/Ch203lecture12009.pdf · • “Pushing Electrons: A guide for students of organic chemistry (Weeks) is very helpful butorganic

CH203 Lecture 1CH203 Lecture 1September 3, 2009

John. A. Porco, Jr.

Department of ChemistryDepartment of [email protected]

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J. A. Porco, Jr.: Brief Biosketch• Ph.D. Harvard University (1992)

A l V t (1993 1995)• Avalon Ventures (1993-1995)• Argonaut Technologies (1995-1999)• Joined the Department of Chemistry at Boston

University as Assistant Professor (1999 )• Confounded Center for Chemical

Methodology and Library Development atMethodology and Library Development at Boston University (CMLD-BU, 2002)

• Promoted to Professor of Chemistry (2004)• Promoted to Professor of Chemistry (2004).

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CH203 AA Logistics

• Instructor: Professor John A. Porco, Jr.• Office: Life Sciences and Engineering Building• Office: Life Sciences and Engineering Building

(LSEB) 802• Office telephone: 353-2493Office telephone: 353 2493• E-mail: [email protected]• Class Location and Meeting Times: Tuesday• Class Location and Meeting Times: Tuesday-

Thursday 8:00-9:20 am, STO B50.• Office hours: Mondays 1-2 PM and Wednesdays 4-5Office hours: Mondays 1 2 PM and Wednesdays 4 5

pm in LSEB 802 or by appointment. Please come at the beginning of the office hour. I will also hang g g f ff garound the class for a few minutes afterwards to answer questions.

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Lecture Textbooks and Other Course Material

• Organic Chemistry 7th Edition by John McMurry (Brooks/Cole) y ( )

• Study Guide and Solutions Manual (Sixth Edition) by Susan McMurryEdition) by Susan McMurry.

• “Pushing Electrons: A guide for students of organic chemistry (Weeks) is very helpful butorganic chemistry (Weeks) is very helpful but not requiredM l l M d l l l f l• Molecular Models are also extremely useful and a variety of types are available in the b k M lik l l il blbookstore. Many sets are likely also available from former organic chemistry students.

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CH203 Objectives

• Develop an appreciation of organic structureand organic substancesg

• Use a functional group approach to organicchemistry chemical reactions and syntheticchemistry, chemical reactions, and synthetictransformations

• Come to an understanding of how chemical• Come to an understanding of how chemicalreactions occur and how reaction mechanismsmay be deducedmay be deduced

• Achieve Personal Goals• Have Fun with it !

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CH203 Course Website

http://people.bu.edu/porcogrp/CH203/CH203.htm

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Meet theMeet theCH203AA Class !AA Class !

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CH203 A1 Discussion Sections

Discussions will begin the week of September 8th and will be led by Bruno Rubio and Joseph Tucker:

CH203 A0 Monday 12:00 – 1:00 pm SCI 111 (BR)CH203 A1 Monday 1:00 2:00 pm SCI 111 (BR)CH203 A1 Monday 1:00 – 2:00 pm SCI 111 (BR)CH203 A2 Monday 2:00 – 3:00 pm SOC B59 (JT)CH203 A3 Monday 3:00 – 4:00 pm SOC B57 (JT)CH203 A3 Monday 3:00 4:00 pm SOC B57 (JT)CH203 A4 Tuesday 9:30 – 10:30 am CAS 312 (BR)CH203 A5 Tuesday 5:00 – 6:00 pm SCI 111 (JT)CH203 A6 Wednesday 2:00 – 3:00 pm BRB 122 (JT)CH203 A7 Wednesday 3:00 – 4:00 pm CAS 223 (JT)CH203 A8 W d d 4 00 5 00 SCI 113 (BR)CH203 A8 Wednesday 4:00 – 5:00 pm SCI 113 (BR)CH203 A9 Thursday 12:00 – 1:00 pm SOC B57 (BR)

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CH203 A1 Course GradingTotal Points % Letter Grade

>368 >92 A

352<368 88-92 A-352<368 88 92 A

340<352 85-88 B+

324<340 81 85 B324<340 81-85 B

312<324 78-81 B-

72 78 C288<312 72-78 C+

256<288 64-72 C

232<256 58-64 C-

200<232 50-58 D

<200 <50 F

The final grades will be based on 400 points (300 points for examinations and 100 points for the laboratory)

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CH203 AA ExamsThere will be three (3) ‘in-class’ examinations during theThere will be three (3) in-class examinations during the

semester (1.5 h) and a final examination (2 h). There are no "make-up" exams

If the median grade of an examination gis less than 75%, the median grade will be raised to a 75% by

adding a constant amount (not more than 20%, however) to the grade of each student. If the median grade is greater than 75%, the grades will

not be changed. You may drop one of the “in class”

examinations for any reason, but not the final examination. E h i i i h 100Each examination is worth 100 pts.

Dates of Examinations: October 1 (Thurs.), November 5 (Thurs.), and December 3 (Thurs.)

(Location: STO B50 and other rooms)(Location: STO B50 and other rooms).

Final Exam: December 17, 2008 12:30-2:30 pm. Locations: TBDDecember 17, 2008 12:30 2:30 pm. Locations: TBD

http://www.bu.edu/cas/undergraduate/conductcode.html

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Other Helpful Hints:

1) Attend the Lecture !

2) Keep up with the material

3) Review and rewrite your lecture notes after every lecture3) Review and rewrite your lecture notes after every lecture

4) Prepare notecards for key concepts and reactions/mechanisms

5) Form study groups (maximum of four students)

6) Find problems at the end of the chapter that correspond to the lecture material

7) Don't cram for exams

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Tentative Schedule of Topics from McMurry (7th Edition)

Chapter 1: Structure and BondingChapter 2: Polar Covalent Bonds; Acids and BasesChapter 3: Organic Compounds: Alkanes and Their StereochemistryChapter 4: Organic Compounds: Cycloalkanes and Their SteroechemChapter 5: An Overview of Organic ReactionsChapter 5: An Overview of Organic ReactionsChapter 6: Alkenes: Structure and ReactivityChapter 7: Alkenes: Reactions and SynthesisCh t 8 Alk A I t d ti t O i S th iChapter 8: Alkynes : An Introduction to Organic SynthesisChapter 9: StereochemistryChapter 10: OrganohalidesChapter 11: Reactions of Alkyl Halides: Nucleophilic Substitutions and EliminationsChapter 13: Structure Determination: Nuclear Magnetic ResonanceChapter 13: Structure Determination: Nuclear Magnetic ResonanceSpectroscopyAssigned problems for each chapter will be provided in lecture

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Examples of Organic Molecules as Drugs

Penicillin (antibiotic)( )

caffeine (stimulant)

Page 15: John. A. Porco, Jr.people.bu.edu/porcogrp/CH203/Lecture/Ch203lecture12009.pdf · • “Pushing Electrons: A guide for students of organic chemistry (Weeks) is very helpful butorganic
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The Crystal Lattice of Diamond

Page 17: John. A. Porco, Jr.people.bu.edu/porcogrp/CH203/Lecture/Ch203lecture12009.pdf · • “Pushing Electrons: A guide for students of organic chemistry (Weeks) is very helpful butorganic

Representations of Orbitals

Electron cloud plots

Page 18: John. A. Porco, Jr.people.bu.edu/porcogrp/CH203/Lecture/Ch203lecture12009.pdf · • “Pushing Electrons: A guide for students of organic chemistry (Weeks) is very helpful butorganic
Page 19: John. A. Porco, Jr.people.bu.edu/porcogrp/CH203/Lecture/Ch203lecture12009.pdf · • “Pushing Electrons: A guide for students of organic chemistry (Weeks) is very helpful butorganic
Page 20: John. A. Porco, Jr.people.bu.edu/porcogrp/CH203/Lecture/Ch203lecture12009.pdf · • “Pushing Electrons: A guide for students of organic chemistry (Weeks) is very helpful butorganic

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Page 21: John. A. Porco, Jr.people.bu.edu/porcogrp/CH203/Lecture/Ch203lecture12009.pdf · • “Pushing Electrons: A guide for students of organic chemistry (Weeks) is very helpful butorganic

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Page 22: John. A. Porco, Jr.people.bu.edu/porcogrp/CH203/Lecture/Ch203lecture12009.pdf · • “Pushing Electrons: A guide for students of organic chemistry (Weeks) is very helpful butorganic

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Page 23: John. A. Porco, Jr.people.bu.edu/porcogrp/CH203/Lecture/Ch203lecture12009.pdf · • “Pushing Electrons: A guide for students of organic chemistry (Weeks) is very helpful butorganic

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Page 24: John. A. Porco, Jr.people.bu.edu/porcogrp/CH203/Lecture/Ch203lecture12009.pdf · • “Pushing Electrons: A guide for students of organic chemistry (Weeks) is very helpful butorganic

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Page 25: John. A. Porco, Jr.people.bu.edu/porcogrp/CH203/Lecture/Ch203lecture12009.pdf · • “Pushing Electrons: A guide for students of organic chemistry (Weeks) is very helpful butorganic

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