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João António de Sampaio Rodrigues Queiroz · 2014. 7. 9. · J.F. Cascalheira, J.A. Queiroz,...

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(Junho 2014) Patentes D.M.F. Prazeres, M.M. Diogo, J.A. Queiroz, “Process for production and purification of plasmid DNA”, Patent Number PT 102491 R; WO 02/04027 A1; United States Patent 7,169,917, January 30, 2007. C. Cruz, E. Cairrao, S. Silvestre, L. Breitenfeld, P. Almeida, J.A. Queiroz, Método para a marcação da mitocôndria e do retículo endoplasmático utilizando compostos macrocíclicos fluorescentes, Patent Number PT 105419, 2012. Capítulos de Livros J.M.L. Rodilla, M.I. Ismael, J.A. Queiroz, J.A. Figueiredo, R. Martins, “Transformation of a Labdane by an Enzymatic Treatment”, Natural Products in the New Millennium: Prospects and Industrial Application, A.P. Rauter, F.B. Palma, J. Justino, M.E. Araújo, S.P. Santos (eds.), Kluwer Academic Publishers, The Netherlands: Dordrecht, pp. 437- 440, 2002. M.M. Diogo, J.A. Queiroz, D.M.F. Prazeres, “Purification of Plasmid DNA Vectors Produced in Escherichia coli for Gene Therapy and DNA Vaccine Applications”, Microbial Processes and Products. Methods in Biotechnology, vol.18, J.-L. Barredo (ed.), Humana Press, Totowa, NJ, pp. 165-178, 2005. F. Sousa, L. Passarinha, J.A. Queiroz, "Biomedical application of plasmid DNA in gene therapy: A new challenge for chromatography", Biotechnology and Genetic Engineering Reviews, 26, 83-116, 2009. João António de Sampaio Rodrigues Queiroz https://www.ubi.pt/SSL/Pagina_Pessoal.aspx?id=jqueiroz http://orcid.org/0000-0002-3096-8325
Transcript
  • (Junho 2014)

    Patentes

    D.M.F. Prazeres, M.M. Diogo, J.A. Queiroz, “Process for production and purification of

    plasmid DNA”, Patent Number PT 102491 R; WO 02/04027 A1; United States Patent

    7,169,917, January 30, 2007.

    C. Cruz, E. Cairrao, S. Silvestre, L. Breitenfeld, P. Almeida, J.A. Queiroz, “Método

    para a marcação da mitocôndria e do retículo endoplasmático utilizando compostos

    macrocíclicos fluorescentes”, Patent Number PT 105419, 2012.

    Capítulos de Livros

    J.M.L. Rodilla, M.I. Ismael, J.A. Queiroz, J.A. Figueiredo, R. Martins, “Transformation

    of a Labdane by an Enzymatic Treatment”, Natural Products in the New Millennium:

    Prospects and Industrial Application, A.P. Rauter, F.B. Palma, J. Justino, M.E. Araújo,

    S.P. Santos (eds.), Kluwer Academic Publishers, The Netherlands: Dordrecht, pp. 437-

    440, 2002.

    M.M. Diogo, J.A. Queiroz, D.M.F. Prazeres, “Purification of Plasmid DNA Vectors

    Produced in Escherichia coli for Gene Therapy and DNA Vaccine Applications”,

    Microbial Processes and Products. Methods in Biotechnology, vol.18, J.-L. Barredo

    (ed.), Humana Press, Totowa, NJ, pp. 165-178, 2005.

    F. Sousa, L. Passarinha, J.A. Queiroz, "Biomedical application of plasmid DNA in gene

    therapy: A new challenge for chromatography", Biotechnology and Genetic

    Engineering Reviews, 26, 83-116, 2009.

    João António de Sampaio Rodrigues Queiroz

    https://www.ubi.pt/SSL/Pagina_Pessoal.aspx?id=jqueiroz

    http://orcid.org/0000-0002-3096-8325

  • A.P. Gomes, J.F. Mano, J.A. Queiroz, I.C. Gouveia, "Assessment of bacteria-textile

    interactions using Scanning Electron Microscopy: A study on LbL chitosan/alginate

    coated cotton”, Microscopy: Science, Technology, Applications and Education, vol.1,

    A. Méndez-Vilas, J. Díaz Álvarez (eds.), Formatex Research Center, pp. 286-292, 2010.

    L. Paulo, M. Oleastro, E. Gallardo, J.A. Queiroz, F. Domingues, “Antimicrobial

    properties of resveratrol: a review”, Science against Microbial Pathogens:

    Communicating Current Research and Technological Advances, Microbiology Book

    Series, A. Méndez-Vilas (ed.), Formatex, pp. 1225-1235, 2011.

    CT Tomaz, J.A. Queiroz, “Hydrophobic Interaction Chromatography”, Liquid

    Chromatography: Fundamentals and Instrumentation, S. Fanali, P.R. Haddad, C.F.

    Poole, P. Schoenmakers, D. Lloyds (eds.), Elsevier, pp 121-141, 2013.

    Publicações científicas/Artigos mais relevantes

    1. J.A. Queiroz, F.A.P. Garcia, J.M.S. Cabral, “Hydrophobic Interaction

    Chromatography of Chromobacterium viscosum Lipase”, Journal of Chromatography

    A, 707, 137-142, 1995.

    2. J.A. Queiroz, F.A.P. Garcia, J.M.S. Cabral, “Partitioning of Chromobacterium

    viscosum Lipases in Aqueous Two-Phase Systems”, Bioseparation, 5, 307-311, 1995.

    3. J.A. Queiroz, F.A.P. Garcia, J.M.S. Cabral, “Hydrophobic Interaction

    Chromatography of Chromobacterium viscosum Lipase on Polyethylene Glycol

    Immobilized on Sepharose”, Journal of Chromatography A, 734, 213-219, 1996.

    4. M.M. Diogo, J.M.S. Cabral, J.A. Queiroz, “Preliminary Study on Hydrophobic

    Interaction Chromatography of Chromobacterium viscosum Lipase on Polypropylene

    Glycol Immobilized on Sepharose”, Journal of Chromatography A, 796, 177-180, 1998.

    5. J.A. Queiroz, F.A.P. Garcia, J.M.S. Cabral, “Purification of a Chromobacterium

  • viscosum Lipase by Hydrophobic Interaction Chromatography”, Isolation &

    Purification, 3, 1-7, 1999.

    6. M.M. Diogo, S. Silva, J.M.S. Cabral, J.A. Queiroz, “Hydrophobic Interaction

    Chromatography of Chromobacterium viscosum Lipase on Polypropylene Glycol

    Immobilized on Sepharose”, Journal of Chromatography A, 849, 413-419, 1999.

    7. J.F. Cascalheira, J.A. Queiroz, “Kinetic Study of the Cellobiase Activity of

    Trichoderma reesei Cellulase Complex at High Substrate Concentrations”,

    Biotechnology Letters, 21, 651-655, 1999.

    8. M.M. Diogo, J.A. Queiroz, G.A. Monteiro, D.M.F. Prazeres, “Separation and

    Analysis of Plasmid Denatured Forms using Hydrophobic Interaction

    Chromatography”, Analytical Biochemistry, 275, 122-124, 1999.

    9. M.A. Esquibel-King, A.C. Dias-Cabral, J.A. Queiroz, N.G. Pinto, “A Study of

    Hydrophobic Interaction Adsorption of Bovine Serum Albumin under Overload

    Conditions using Flow Microcalorimetry”, Journal of Chromatography A, 865, 111-

    122, 1999.

    10. C.T. Tomaz, J.A. Queiroz, "Studies on the Chromatographic Fractionation of

    Trichoderma reesei Cellulases by a Hydrophobic Interaction" Journal of

    Chromatography A, 865, 123-128, 1999.

    11. F.C. Domingues, J.A. Queiroz, J.M.S. Cabral, L.P. Fonseca, “The Influence of

    Culture Conditions on Mycelial Structure and Cellulase Production by Trichoderma

    reesei Rut C-30”, Enzyme and Microbial Technology, 26, 394-401, 2000.

    12. M.M. Diogo, J.A. Queiroz, G.A. Monteiro, S.A.M. Martins, G.N.M. Ferreira,

    D.M.F. Prazeres, “Purification of a Cystic Fibrosis Plasmid Vector for Gene Therapy

    using Hydrophobic Interaction Chromatography”, Biotechnology and Bioengineering,

    68, 576-583, 2000.

    13. M.M. Diogo, S. Ribeiro, J.A. Queiroz, G.A. Monteiro, P. Perrin, N. Tordo, D.M.F.

  • Prazeres, “Scale-up of Hydrophobic Interaction Chromatography for the Purification of

    a DNA Vaccine Against Rabies”, Biotechnology Letters, 22, 1397-1400, 2000.

    14. J.A. Queiroz, C.T. Tomaz, J.M.S. Cabral, “Hydrophobic Interaction

    Chromatography of Proteins”, Journal of Biotechnology, 87, 143-159, 2001.

    15. F.C. Domingues, J.A. Queiroz, J.M.S. Cabral, L.P. Fonseca, “Production of

    Cellulases in Batch Culture using a Mutant Strain of Trichoderma reesei Growing on

    Soluble Carbon Source”, Biotechnology Letters, 23, 771-775, 2001.

    16. M.M. Diogo, S. Ribeiro, J.A. Queiroz, G.A. Monteiro, N. Tordo, P. Perrin, D.M.F.

    Prazeres, “Production, Purification and Analysis of an Experimental DNA Vaccine

    Against Rabies”, The Journal of Gene Medicine, 3, 577-584, 2001.

    17. C.T. Tomaz, D. Duarte, J.A. Queiroz, “Comparative Study on the Fractionation of

    Cellulases on Some Hydrophobic Interaction Chromatography Adsorbents”, Journal of

    Chromatography A, 944, 211-216, 2002.

    18. M.M. Diogo, J.A. Queiroz, D.M.F. Prazeres, “Hydrophobic Interaction

    Chromatography of Homo-oligonucleotides on Derivatized Sepharose CL-6B.

    Application of the Solvophobic Theory”, Journal of Chromatography A, 944, 119-128,

    2002.

    19. A.C. Dias-Cabral, N.G. Pinto, J.A. Queiroz, “Studies on Hydrophobic Interaction

    Adsorption of Bovine Serum Albumin on Polypropylene Glycol-Sepharose under

    Overloaded Conditions”, Separation Science and Technology, 37, 1505-1520, 2002.

    20. C.T. Tomaz, A.S. Rocha, J.A. Queiroz, “Hydrophobic Interaction Chromatography

    of Trichoderma reesei Cellulases on Polypropylene Glycol-Sepharose”, Separation

    Science and Technology, 37, 1641-1651, 2002.

    21. M.M. Diogo, J.A. Queiroz, D.M.F. Prazeres, “Studies on the Retention of Plasmid

    DNA and Escherichia coli Nucleic Acids by Hydrophobic Interaction

    Chromatography”, Bioseparation, 10, 211-220, 2002.

  • 22. A.C. Pardal, M.J. Nunes, A.M. Gama, J.A. Queiroz, P. Almeida, “Preliminary

    Studies on the use of Cyanines as Ligands in Dye-Affinity Chromatography of

    Proteins”, Coloration Technology, 118, 95-99, 2002.

    23. M.M. Diogo, J.A. Queiroz, D.M.F. Prazeres, “Assessment of Purity and

    Quantification of Plasmid DNA in Process Solutions using High Performance

    Hydrophobic Interaction Chromatography”, Journal of Chromatography A, 998, 109-

    117, 2003.

    24. A.C. Dias-Cabral, J.A. Queiroz, N.G. Pinto, “Effect of Salt and Temperature on the

    Adsorption of Bovine Serum Albumin on Polypropylene Glycol-Sepharose under

    Linear and Overloaded Chromatographic Conditions”, Journal of Chromatography A,

    1018, 137-153, 2003.

    25. M.M. Diogo, D.M.F. Prazeres, N.G. Pinto, J.A. Queiroz, “Hydrophobic Interaction

    Chromatography of Homo-oligonucleotides on Derivatized Sepharose CL-6B. Using

    and Relating two Different Models for Describing the Effect of Salt and Temperature on

    Retention”, Journal of Chromatography A, 1006, 137-148, 2003.

    26. C.T. Tomaz, J.A. Queiroz, “Fractionation of Trichoderma reesei Cellulases by

    Hydrophobic Interaction Chromatography on Phenyl-Sepharose”, Biotechnology

    Letters, 26, 223-227, 2004.

    27. M.M. Diogo, J.A. Queiroz, D.M.F. Prazeres, “Chromatography of Plasmid DNA”,

    Journal of Chromatography A, 1069, 3-22, 2005.

    28. F. Sousa, C.T. Tomaz, D.M.F. Prazeres, J.A. Queiroz, “Separation of supercoiled

    and open circular Plasmid DNA Isoforms by Chromatography with a Histidine-Agarose

    Support”, Analytical Biochemistry, 343, 183-185, 2005.

    29. S. Ferreira, F. Sousa, J.A. Queiroz, F.C. Domingues, “Improved Recovery of a

    Fusion Protein Containing the Antigenic Domain 1 of the Human Cytomegalovirus

    Glycoprotein B”, Biotechnology Letters, 27, 1241-1245, 2005.

  • 30. A.C. Dias-Cabral, A.S. Ferreira, J. Phillips, J.A. Queiroz, N.G. Pinto, “The Effects

    of Ligand Chain Length, Salt Concentration and Temperature on the Adsorption of

    Bovine Serum Albumin onto Polypropylene Glycol-Sepharose”, Biomedical

    Chromatography, 19, 606-616, 2005.

    31. L.A. Passarinha, M.M. Diogo, J.A. Queiroz, G.A. Monteiro, L.P. Fonseca, D.M.F.

    Prazeres, “Production of ColE1 Type Plasmid by Escherichia coli DH5α Cultured under

    Non-Selective Conditions”, Journal of Microbiology and Biotechnology, 16, 20-24,

    2006.

    32. L.A. Passarinha, M.J. Bonifácio, J.A. Queiroz, “The Effect of Temperature on the

    Analysis of Methanephrine for Catechol-O-Methyltransferase Activity Assay by HPLC

    with Electrochemical Detection”, Biomedical Chromatography, 20, 937-944, 2006.

    33. F. Sousa, S. Ferreira, J.A. Queiroz, F.C. Domingues, “Production of a Fusion

    Protein Containing the Antigenic Domain 1 of the Human Cytomegalovirus

    Glycoprotein B”, Journal of Microbiology and Biotechnology, 16, 1026-1031, 2006.

    34. F. Sousa, A. Melo, S. Almeida, P. Paixão, J.A. Queiroz, F.C. Domingues, “Isolation

    of a Fusion Protein Containing the Antigenic Domain 1 of the Human Cytomegalovirus

    Glycoprotein B and its Application in ELISA Tests”, Biotechnology Letters, 28, 73-77,

    2006.

    35. F. Sousa, S. Freitas, A. Azzoni, D.M.F. Prazeres, J.A. Queiroz, “Selective

    Purification Plasmid DNA from Clarified Cell Lysates with a Single Histidine-Agarose

    Chromatography Step”, Biotechnology and Applied Biochemistry, 45, 131-140, 2006.

    36. L.A. Passarinha, M.J. Bonifácio, J.A. Queiroz, “Comparative Study on the

    Interaction of Recombinant Soluble Catechol-O-Methyltransferase on Some

    Hydrophobic Adsorbents”, Biomedical Chromatography, 21, 430-438, 2007.

    37. A. Oudia, E. Mészáros, R. Simões, J.A. Queiroz, E. Jakab, “ Pyrolysis-GC/MS and

  • TG/MS Study of Mediated Laccase Biodelignification of Eucalyptus globulus Kraft

    Pulp”, Journal of Analytical and Applied Pyrolysis, 78, 233-242, 2007.

    38. F. Sousa, D.M.F. Prazeres, J.A. Queiroz, “Dynamic binding capacity of plasmid

    DNA in histidine-agarose chromatography”, Biomedical Chromatography, 21, 993-998,

    2007.

    39. F. Sousa, D.M.F. Prazeres, J.A. Queiroz, “Circular dichroism investigation of the

    effect of plasmid DNA structure on retention in histidine chromatography", Archives of

    Biochemistry and Biophysics, 467, 154-162, 2007.

    40. M. Barroso, M. Dias, D.N. Vieira, J.A. Queiroz, M. López-Rivadulla,

    "Development and validation of an analytical method for the simultaneous

    determination of cocaine and its main metabolite, benzoylecgonine, in human hair by

    gas chromatography-mass spectrometry", Rapid Communications in Mass

    Spectrometry, 22, 3320-3326, 2008.

    41. R.E.F. Boto, P. Almeida, J.A.Queiroz, “Thiacarbocyanine as ligand in dye-affinity

    chromatography for protein purification”, Biomedical Chromatography, 22, 278-288,

    2008.

    42. E. Gallardo, J.A. Queiroz, “The role of alternative specimens on toxicological

    analysis", Biomedical Chromatography, 22, 795-821, 2008.

    43. I. Gouveia, J.M. Fiadeiro, J.A. Queiroz, "Combined bio-carbonization and dyeing of

    wool: a possibility using cell-wall-degrading enzymes and 1:1 metal-complex dyes",

    Engineering in Life Sciences, 8, 250-259, 2008.

    44. I. Gouveia, J.M. Fiadeiro, J.A. Queiroz, "Enzymatic Application to Remove Plant

    Residues from Wool: Preliminary Experiments Evaluating the Effect of Trichoderma

    reesei Cellulases and Aspergillus aculeatus Pectinases and Hemicellulases", AATCC

    Review, 8, 38-44, 2008.

    45. I. Gouveia, J.M. Fiadeiro, J.A. Queiroz, "Enzymatic removal of plant residues from

  • wool: application of experimental design techniques for optimization parameters",

    Biochemical Engineering Journal, 41, 157-165, 2008.

    46. A. Morão, M.T.P. Amorim, A. Lopes, I. Escobar, J.A. Queiroz, "Characterisation of

    ultrafiltration and nanofiltration membranes from rejections of neutral reference solutes

    using a model of asymmetric pores", Journal of Membrane Science, 319, 64-75, 2008.

    47. A. Oudia, J.A. Queiroz, R. Simões, "Potential and Limitation of Trametes versicolor

    laccase on Biodegradation of Eucalyptus globulus and Pinus pinaster kraft pulp",

    Enzyme and Microbial Technology, 43, 144-148, 2008.

    48. A. Oudia, J.A. Queiroz, R. Simões, "The influence of operating parameters on the

    delignification of Eucalyptus globulus kraft pulps in a laccase-violuric acid system",

    Applied Biochemistry and Biotechnology, 149, 23-32, 2008.

    49. L.A. Passarinha, M.J. Bonifácio, P. Soares-da-Silva, J.A. Queiroz, "A new approach

    on the purification of Recombinant Human Soluble Catechol-O-Methyltransferase from

    an Escherichia coli extract using Hydrophobic Interaction Chromatography", Journal of

    Chromatography A, 1177, 287-296, 2008.

    50. A. Sousa, L.A. Passarinha, L. Rodrigues, J.A. Teixeira, A. Mendonça, J.A. Queiroz,

    “Separation of different forms of proteose peptone 3 by hydrophobic interaction

    chromatography with a dual salt system”, Biomedical Chromatography, 22, 447–449,

    2008.

    51. F. Sousa, T. Matos, D.M.F. Prazeres, J.A. Queiroz, “Specific recognition of

    supercoiled plasmid DNA in arginine affinity chromatography”, Analytical

    Biochemistry, 374, 432-434, 2008.

    52. F. Sousa, D.M.F. Prazeres, J.A. Queiroz, "Affinity chromatography approaches to

    overcome the challenges of purifying plasmid DNA", Trends in Biotechnology, 26,

    518-525, 2008.

    53. F. Sousa, D.M.F. Prazeres, J.A. Queiroz, "Binding and elution strategy for improved

  • performance of arginine affinity chromatography in supercoiled plasmid DNA

    purification", Biomedical Chromatography, 23, 160-165, 2009.

    54. F. Sousa, D.M.F. Prazeres, J.A. Queiroz, "Improvement of transfection efficiency by

    using supercoiled plasmid DNA purified with arginine affinity chromatography",

    Journal of Gene Medicine, 11, 79-88, 2009.

    55. R.E.F. Boto, U. Anyanwu, F.Sousa, P. Almeida, J.A. Queiroz, “Thiacarbocyanine as

    ligand in dye-affinity chromatography for protein purification. II.Dynamic binding

    capacity using lysozyme as a model”, Biomedical Chromatography, 23, 988-993, 2009.

    56. A. Oudia, E. Mészáros, E. Jakab, R. Simões, J.A. Queiroz, A. Ragauskas, L. Novak,

    “Analytical pyrolysis study of biodelignification of cloned Eucalyptus globulus and

    Pinus pinaster aiton kraft pulp and residual lignins”, Journal of Analytical and Applied

    Pyrolysis, 85, 19-29, 2009.

    57. A. Sousa, F. Sousa, D.M.F. Prazeres, J.A. Queiroz, “Histidine affinity

    chromatography of homo-oligonucleotides. Role of multiple interactions on retention”,

    Biomedical Chromatography, 23, 745-753, 2009.

    58. A. Sousa, F. Sousa, J.A. Queiroz, "Selectivity of arginine chromatography in

    promoting different interactions using synthetic oligonucleotides as model", Journal of

    Separation Science, 32, 1665-1672, 2009.

    59. E. Gallardo, M. Barroso, J.A. Queiroz, “LC/MS: A Powerful Tool in Workplace

    Drug Testing” Drug Testing and Analysis, 1, 109-115, 2009.

    60. A. Morão, J.C. Nunes, F. Sousa, M.T.P. Amorim, I. Escobar, J.A. Queiroz,

    "Development of a Model for Membrane Filtration of Long and Flexible

    Macromolecules: Application to Predict Dextran and Linear DNA Rejections in

    Ultrafiltration", Journal of Membrane Science, 336, 61-70, 2009.

    61. F. Silva, L. Passarinha, F. Sousa, J.A. Queiroz, F.C. Domingues, "Influence of

  • growth conditions on plasmid DNA production"; Journal of Microbiology and

    Biotechnology, 19, 1408-1414, 2009.

    62. M. Barroso, E. Gallardo, J.A. Queiroz, “Bioanalytical Methods for the

    Determination of Cocaine and Metabolites in Human Biological Samples”, Bioanalysis,

    1, 977-1000, 2009.

    63. E. Gallardo, M. Barroso, J.A. Queiroz, “Current Technologies and Considerations

    for Drug Bioanalysis in Oral Fluid”, Bioanalysis, 1, 637-667, 2009.

    64. A. Palmeira-de-Oliveira, L. Salgueiro, R. Palmeira-de-Oliveira, J. Martinez-de-

    Oliveira, C. Pina-Vaz, J.A. Queiroz, A.G. Rodrigues, “Anti-Candida activity of

    essential oils: A Review”; Mini Reviews in Medicinal Chemistry, 9, 1292-1305, 2009.

    65. L. Passarinha, M.J. Bonifácio, J.A. Queiroz,"Application of a fed-batch bioprocess

    for the heterologous production of hSCOMT in Escherichia coli", Journal of

    Microbiology and Biotechnology, 19, 972-981, 2009.

    66. A. Sousa, F. Sousa, J.A. Queiroz, "Biorecognition of supercoiled plasmid DNA

    isoform in lysine-affinity chromatography", Journal of Chromatography B, 877, 3257-

    3260, 2009.

    67. S. Ferreira, A.P. Duarte, M.H. Ribeiro, J.A. Queiroz, F.C. Domingues, "Response

    surface optimization of enzymatic hydrolysis of Cistus ladanifer and Cystus striatus for

    bioethanol production", Biochemical Engineering Journal, 45, 192-200, 2009.

    68. S. Ferreira, A.P. Duarte, M.H. Ribeiro, J.A. Queiroz, F.C. Domingues, "Influence of

    buffer systems on Trichoderma reesei Rut C-30 morphology and cellulase production",

    Electronic Journal of Biotechnology, 12 (3), 2009.

    69. F. Sousa, L. Passarinha, J.A. Queiroz, "Biomedical application of plasmid DNA in

    gene therapy: A new challenge for chromatography", Biotechnology and Genetic

    Engineering Reviews, 26, 83-116, 2009.

  • 70. A. Silva, R.E.F. Boto, C.T. Tomaz, J.A Queiroz, P. Almeida, "Rhodamine B as

    ligand for affinity chromatography. Chromatographic studies on derivatized beaded

    cellulose", Journal of Chromatographic Science, 48, 240-244, 2010.

    71. M. Barroso, M. Dias, D.N. Vieira, M. López- Rivadulla, J.A. Queiroz,

    “Simultaneous quantitation of morphine, 6-acetylmorphine, codeine, 6-acetylcodeine

    and tramadol in hair using mixed mode solid-phase extraction and gas chromatography-

    mass spectrometry”, Analytical and Bioanalytical Chemistry, 396, 3059-3069, 2010.

    72. F. Silva, O. Lourenço, C. Pina-Vaz, A.G. Rodrigues, J.A. Queiroz, F.C. Domingues,

    “The use of DRAQ5 to monitor intracellular DNA in Escherichia coli by flow

    cytometry”, Journal of Fluorescence, 20, 907-914, 2010.

    73. L. Paulo, S. Ferreira, E. Gallardo, J.A. Queiroz, F.C. Domingues, “Antimicrobial

    activity and effects of resveratrol on human pathogenic bacteria”, World Journal of

    Microbiology and Biotechnology, 26, 1533-1538, 2010.

    74. V.S. Nunes, M.J. Bonifácio, J.A. Queiroz, L.A. Passarinha, "Assessment of COMT

    isolation by HIC using a dual salt system and low temperature", Biomedical

    Chromatography, 24, 858-862, 2010.

    75. A. Palmeira-de-Oliveira, M.P. Ribeiro, R. Palmeira-de-Oliveira, C. Gaspar, S.

    Costa-de-Oliveira, I.J. Correia, J.A. Queiroz, C. Pina-Vaz, J. Martinez-de-Oliveira,

    A.G. Rodrigues, “Anticandida activity of a chitosan hydrogel: Mechanism of action and

    cytotoxicity profile”, Gynecologic and Obstetric Investigation, 70, 322-327, 2010.

    76. M. Barroso, M. Dias, D.N. Vieira, M. López-Rivadulla, J.A. Queiroz, “Mixed-mode

    solid-phase extraction for sample cleanup in hair analysis for methadone and its main

    metabolite”, Biomedical Chromatography, 24, 1240-1246, 2010.

    77. S. Ferreira, N. Gil, A.P. Duarte, J.A. Queiroz, F.C. Domingues, “Bioethanol from

    the portuguese forest residue Pterospartum tridentatum - An evaluation of pretreatment

    strategy for enzymatic saccharification and sugars fermentation”, Bioresource

    Technology, 101, 7797-7803, 2010.

  • 78. F. Sousa, C. Cruz, J.A. Queiroz, "Amino acids-nucleotides biomolecular

    recognition: From biological occurrence to affinity chromatography", Journal of

    Molecular Recognition, 23, 505-518, 2010.

    79. I.C. Gouveia, L.P. Dias, J.M. Fiadeiro, J.A. Queiroz, “Enzymatic Treatments to

    Improve the Dyeability of Linen Fabrics: Optimization and Empirical Modeling using

    Experimental Design Techniques”, Textile Research Journal, 80, 1602-1615, 2010.

    80. M. Barroso, S. Costa, M. Dias, D.N. Vieira, J.A. Queiroz, M. López-Rivadulla,

    “Analysis of phenylpiperazine-like stimulantes in human hair as trimethylsilyl

    derivatives by gas chromatography-mass spectrometry”, Journal of Chromatography A,

    1217, 6274-6280, 2010.

    81. R. Raposo, M. Barroso, S. Fonseca, S. Costa, J.A. Queiroz, E. Gallardo, M. Dias,

    “Determination of eight selected organophosphorus insecticides in postmortem blood

    samples using solid-phase extraction and gas chromatography/mass spectrometry”,

    Rapid Communications in Mass Spectrometry, 21, 3187-3194, 2010.

    82. R. Martins, J.A. Queiroz, F. Sousa, “A new affinity approach to isolate Escherichia

    coli 6S RNA with histidine-chromatography”, Journal of Molecular Recognition, 23,

    519, 524, 2010.

    83. A. Sousa, F. Sousa, J.A. Queiroz, “Differential interactions of plasmid DNA, RNA

    and genomic DNA with amino acid-based affinity matrices”, Journal of Separation

    Science, 33, 2610-2618, 2010.

    84. C. Cruz, E.J. Cabrita, J.A. Queiroz, “Analysis of nucleotides binding to

    chromatography supports provided by nuclear magnetic resonance spectroscopy”,

    Journal of Chromatography A, 1218, 3559-3564, 2011.

    85. M. Barroso, E. Gallardo, D.N. Vieira, M. López-Rivadulla, J.A. Queiroz. “Hair: a

    complementary source of bioanalytical information in forensic toxicology”,

    Bioanalysis, 3, 67-79, 2011.

  • 86. V.M. Gaspar, F. Sousa, J.A. Queiroz, I.J. Correia, “Formulation of chitosan-TPP-

    pDNA nanocapsules for gene therapy applications”, Nanotechnology, 22, 015101,

    2011.

    87. S. Ferreira, N. Gil, J.A. Queiroz, A.P. Duarte, F.C. Domingues, “An evaluation of

    the potential of Acacia dealbata as raw material for bioethanol production”,

    Bioresource Technolology, 102, 4766-4773, 2011.

    88. L. Paulo, F.C. Domingues, J.A. Queiroz, E. Gallardo, “Development and Validation

    of an Analytical Method for the Determination of trans- and cis-Resveratrol in Wine:

    Analysis of Its Contents in 186 Portuguese Red Wines”, Journal of Agricultural and

    Food Chemistry, 59, 2157-2168, 2011.

    89. L. Paulo, M. Oleastro, E. Gallardo, J.A. Queiroz, F.C. Domingues, “Anti-

    helicobacter pylori and urease inhibitory activities of resveratrol and red wine” Food

    Research International, 44, 964-969, 2011.

    90. F. Silva, O. Lourenço, C. Maia, J.A. Queiroz, F.C. Domingues, “Impact of plasmid

    induction strategy on overall plasmid DNA yield and E. coli physiology using flow

    cytometry and real-time PCR”, Process Biochemistry, 46, 174-181, 2011.

    91. F. Sousa, J.A. Queiroz, “Supercoiled plasmid quality assessment by analytical

    arginine-affinity chromatography”, Journal of Chromatography A, 1218, 124-129, 2011.

    92. F. Silva, O. Lourenço, J.A. Queiroz, F.C. Domingues, “Bacteriostatic versus

    bactericidal activity of ciprofloxacin in Escherichia coli assessed by flow cytometry

    using a novel far-red dye”, Journal of Antibiotics, 64, 321-325, 2011.

    93. A. Sousa, D. Bicho, C.T. Tomaz, F. Sousa, J.A. Queiroz, “Performance of a non-

    grafted monolithic support for purification of supercoiled plasmid DNA”, Journal of

    Chromatography A, 1218, 1701-1706, 2011.

    94. S.R. Costa, M.J. Bonifácio, J.A. Queiroz, L.A. Passarinha, “Analysis of hSCOMT

  • adsorption in bioaffinity chromatography with immobilized amino acids: The influence

    of pH and ionic strength”, Journal of Chromatography B, 879, 1704-1706, 2011.

    95. M. Barroso, E. Gallardo, D.N. Vieira, J.A. Queiroz, M. López-Rivadulla,

    “Bioanalytical procedures and recent developments in the determination of

    opiates/opioids in human biological samples”, Analytical and Bioanalytical Chemistry,

    400, 1665-1690, 2011.

    96. C. Cruz, R.E.F. Boto, P. Almeida, J.A. Queiroz, “Study of specific interactions

    between nucleotides and dye support by NMR”, Journal of Molecular Recognition, 24,

    975-980, 2011.

    97. A. Morão, J.C. Nunes, F. Sousa, M.T.P. Amorim, I.C. Escobar, J.A. Queiroz,

    “Ultrafiltration of supercoiled plasmid DNA: modelling and application”, Journal of

    Membrane Science, 378, 280-289, 2011.

    98. C. Cruz, E.J. Cabrita, J.A. Queiroz, “Screening nucleotide binding to amino acid

    coated supports by surface plasmon resonance and nuclear magnetic resonance”,

    Analytical and Bioanalytical Chemistry, 401, 983-993, 2011.

    99. F. Silva, S. Ferreira, J.A. Queiroz, F.C. Domingues, “Coriander (Coriandrum

    sativum L.) essential oil: its antibacterial activity and mode of action evaluated by flow

    cytometry”, Journal of Medical Microbiology, 60, 1479-1486, 2011.

    100. A.Q. Pedro, M.J. Bonifácio, J.A. Queiroz, C.J. Maia, L.A. Passarinha, “A novel

    prokaryotic expression system for biosynthesis of recombinant human membrane-bound

    catechol-O-methyltransferase”, Journal of Biotechnology, 156, 141-146, 2011.

    101. A. Sousa, F. Sousa, J.A. Queiroz, “Impact of lysine-affinity chromatography on

    supercoiled plasmid DNA purification”, Journal of Chromatography B, 879, 3507-3515,

    2011.

    102. A. Sousa, C.T. Tomaz, F. Sousa, J.A. Queiroz, “Successful application of

    monolithic innovative technology using a carbonyldiimidazole disk to purify

  • supercoiled plasmid DNA suitable for pharmaceutical applications, Journal of

    Chromatography A, 1218, 8333-8343, 2011.

    103. D. Costa, A.J.M. Valente, M. Graça Miguel, J.A. Queiroz, “Gel network

    photodisruption: a new strategy for the codelivery of plasmid DNA and drugs”,

    Langmuir, 27, 13780-13789, 2011.

    104. C. Cruz, E. Cairrão, S. Silvestre, L. Breitenfeld, P. Almeida, J.A. Queiroz,

    “Targeting of mitochondria-endoplasmic reticulum by fluorescent macrocyclic

    compounds”, PLoS One, 6, e27078, 2011.

    105. A. Palmeira-de-Oliveira, L.A. Passarinha, C. Gaspar, R. Palmeira-de-Oliveira, B.

    Sarmento, J. Martinez-de-Oliveira, C. Pina-Vaz, A.G. Rodrigues, J.A. Queiroz, “The

    relationship between Candida species charge density and chitosan activity evaluated by

    ion-exchange chromatography”, Journal of Chromatography B, 879, 3749-3751, 2011.

    106. V.M. Gaspar, I.J. Correia, A. Sousa, F. Silva, C.M. Paquete, J.A. Queiroz, F.

    Sousa, “Nanoparticle mediated delivery of pure p53 supercoiled plasmid DNA for gene

    therapy”, Journal of Controlled Release, 156, 212-222, 2011.

    107. I.E. Moreno, B.M. da Fonseca, M. Barroso, S. Costa, J.A. Queiroz, E. Gallardo,

    “Determination of piperazine-type stimulants in human urine by means of

    microextraction in packed sorbent and high performance liquid chromatography-diode

    array detection”, Journal of Pharmaceutical and Biomedical Analysis, 61, 93-99, 2012

    108. D. Costa, J.A. Queiroz, M.G. Miguel, B. Lindman, “Swelling behavior of a new

    biocompatible plasmid DNA hydrogel”, Colloids and Surfaces B: Biointerfaces, 92,

    106-112, 2012.

    109. I.E. Moreno, B.M. da Fonseca, A.R. Magalhães, V.S. Geraldes, J.A. Queiroz, M.

    Barroso, S. Costa, E. Gallardo, “Rapid determination of piperazine-type stimulants in

    human urine by microextraction in packed sorbent after method optimization using a

    multivariate approach”, Journal of Chromatography A, 1222, 116-120, 2012.

  • 110. F. Silva, J.A. Queiroz, F.C. Domingues, “Evaluating metabolic stress and plasmid

    stability in plasmid DNA production by Escherichia coli”, Biotechnology Advances, 30,

    691-708, 2012.

    111. B.M. da Fonseca, I.E. Moreno, A.R. Magalhães, M. Barroso, J.A. Queiroz, S.

    Ravara, J. Calheiros, E. Gallardo, “Determination of biomarkers of tobacco smoke

    exposure in oral fluid using solid-phase extraction and gas chromatography-tandem

    mass spectrometry”, Journal of Chromatography B, 15, 889-890, 116-122, 2012.

    112. A. Palmeira-de-Oliveira, C. Gaspar, R. Palmeira-de-Oliveira, A. Silva-Dias, L.

    Salgueiro, C. Cavaleiro, C. Pina-Vaz, J. Martinez-de-Oliveira, J.A. Queiroz, A.G.

    Rodrigues, “The anti-Candida activity of Thymbra capitata essential oil: effect upon

    pre-formed biofilm”, Journal of Ethnopharmacology, 140, 379-383, 2012.

    113. F. Silva, J.A. Queiroz, F.C. Domingues, “Plasmid DNA fermentation strategies:

    influence on plasmid stability and cell physiology”, Applied Microbiology and

    Biotechnology, 93, 2571-2580, 2012.

    114. R. Martins, J.A. Queiroz, F. Sousa, “Histidine affinity chromatography-based

    methodology for the simultaneous isolation of Escherichia coli small and ribosomal

    RNA”, Biomedical Chromatography, 26, 781-788, 2012.

    115. R. Silva, S. Ferreira, M.J. Bonifácio, J.M. Dias, J.A. Queiroz, L.A. Passarinha,

    “Optimization of fermentation conditions for the production of human soluble catechol-

    O-methyltransferase by Escherichia coli using artificial neural network”, Journal of

    Biotechnology, 160, 161-168, 2012.

    116. S. Ferreira, J. Santos, A. Duarte, A.P. Duarte, J.A. Queiroz, F.C. Domingues,

    “Screening of antimicrobial activity of Cistus ladanifer and Arbutus unedo extracts”,

    Natural Product Research, 26, 1558-1560, 2012.

    117. M. Barroso, I.E. Moreno, B.M. da Fonseca, J.A. Queiroz, E. Gallardo, “Role of

    microextraction sampling procedures in forensic toxicology”, Bioanalysis, 4, 1805-

    1826, 2012.

  • 118. J.C. Nunes, A.M. Morão, C. Nunes, M.T.P. Amorim, I.C. Escobar, J.A. Queiroz,

    “Plasmid DNA recovery from fermentation broths by a combined process of micro- and

    ultrafiltration: modeling and application”, Journal of Membrane Science, 415, 24-35,

    2012.

    119. D. Costa, A.J.M. Valente, M.G. Miguel, J.A. Queiroz, “Plasmid DNA Microgels

    for a therapeutical strategy combining the delivery of genes and anticancer drugs”

    Macromolecular Bioscience, 12, 1243-1252, 2012.

    120. C. Cruz, A. Sousa, F. Sousa, J.A. Queiroz, “Study of the specific interaction

    between L-methionine chromatography support and nucleotides”, Journal of

    Chromatography B, 909, 1-5, 2012.

    121. A.P. Gomes, J.F. Mano, J.A. Queiroz, I.C. Gouveia, “Layer-by-layer deposition of

    antibacterial polyelectrolytes on cotton fibres”, Journal of Polymers and the

    Environment, 20, 1084-1094, 2012.

    122. A. Sousa, F. Sousa, J.A. Queiroz, "Advances in chromatographic supports for

    pharmaceutical-grade plasmid DNA purification", Journal of Separation Science, 35,

    3046-3058, 2012.

    123. R. Martins, C. Maia, J.A. Queiroz, F. Sousa, "A new strategy for RNA isolation

    from eukaryotic cells using arginine affinity chromatography", Journal of Separation

    Science, 35, 3217-3226, 2012.

    124. V.M. Gaspar, C. Cruz, J.A. Queiroz, C. Pichon, I.J. Correia, F. Sousa, “Sensitive

    detection of peptide-minicircle DNA interactions by surface plasmon resonance”,

    Analytical Chemistry, 85, 2304-2311, 2013.

    125. M. Rodrigues, G. Alves, M. Rocha, J.A. Queiroz, A. Falcão, “First liquid

    chromatographic method for the simultaneous determination of amiodarone and

    desethylamiodarone in human plasma using microextraction by packed sorbent (MEPS)

    as sample preparation procedure”, Journal of Chromatography B, 913-914, 90-97, 2013.

  • 126. S. Ferreira, M.J. Fraqueza, J.A. Queiroz, F.C. Domingues, M. Oleastro, “Genetic

    diversity, antibiotic resistance and biofilm-forming ability of Arcobacter butzleri

    isolated from poultry and environment from a Portuguese slaughterhouse” International

    Journal of Food Microbiology, 162, 82-88, 2013.

    127. C. Cruz, A. Sousa, F. Sousa, J.A. Queiroz, “Affinity analysis between immobilized

    L-arginine and plasmid isoforms provided by surface plasmon resonance”, Analytical

    Methods, 5, 1682-1686, 2013.

    128. I. Moreno, B. da Fonseca, D. Oppolzer, A. Martinho, M. Barroso, A. Cruz, J.A.

    Queiroz, E. Gallardo, “Analysis of Salvinorin A in urine using microextraction in

    packed syringe and GC-MS/MS”, Bioanalysis, 5, 661-668, 2013.

    129. C. Cruz, S.D. Santos, E.J. Cabrita, J.A. Queiroz, “Binding analysis between L-

    histidine immobilized and oligonucleotides by SPR and NMR”, International Journal of

    Biological Macromolecules, 56, 175-180, 2013.

    130. A.M. Goncalves, A.Q. Pedro, C. Maia, F. Sousa, J.A. Queiroz, L.A. Passarinha,

    “Pichia pastoris: a recombinant microfactory for antibodies and human membrane

    proteins, Journal of Microbiology and Biotechnology, 23, 587-601, 2013.

    131. D. Oppolzer, I. Moreno, B. da Fonseca, L. Passarinha, M. Barroso, S. Costa, J.A.

    Queiroz, E. Gallardo, “Analytical approach to determine biogenic amines in urine using

    microextraction in packed syringe and liquid chromatography coupled to

    electrochemical detection”, Biomedical Chromatography, 27, 608-614, 2013.

    132. C. Cruz, E. Cairrão, O. Lourenço, P.A. Almeida, I. Verde, J.A. Queiroz,

    “Polyazamacrocycles as potential antitumor agents for human prostate cancer cells”,

    Chemical Biology & Drug Design, 81, 517-526, 2013.

    133. E. Mota, A. Sousa, U. Cernigoj, J.A. Queiroz, C.T. Tomaz, F. Sousa, “Rapid

    quantification of supercoiled plasmid deoxyribonucleic acid using a monolithic ion

    exchanger”, Journal of Chromatography A, 1291, 114-121, 2013.

  • 134. F.M. Santos, A.Q. Pedro, R.F. Soares, R. Martins, M.J. Bonifácio, J.A. Queiroz,

    L.A. Passarinha, “Performance of hydrophobic interaction ligands for human

    membrane-bound catechol-O-methyltransferase purification”, Journal of Separation

    Science, 36, 1693-1702, 2013.

    135. G. Alves, M. Rodrigues, A. Fortuna, A. Falcão, J.A. Queiroz, “A critical review of

    microextraction by packed sorbent as a sample preparation approach in drug

    bioanalysis”, Bioanalysis, 5, 1409-1442, 2013.

    136. V.M. Gaspar, J.G. Marques, F. Sousa, R.O. Louro, J.A. Queiroz, I.J. Correia,

    “Biofunctionalized nanoparticles with pH-responsive and cell penetrating blocks for

    gene delivery”, Nanotechnology, 24, 275101, 2013.

    137. B.M. da Fonseca, I.E. Moreno, M. Barroso, S. Costa, J.A. Queiroz, E. Gallardo,

    “Determination of seven selected antipsychotic drugs in human plasma using

    microextraction in packed sorbent and gas chromatography-tandem mass spectrometry”,

    Analytical and Bioanalytical Chemistry, 405, 3953-3963, 2013.

    138. M. Rodrigues, G. Alves, A. Ferreira, J.A. Queiroz, A. Falcão, “A rapid HPLC

    method for the simultaneous determination of amiodarone and its major metabolite in

    rat plasma and tissues; a useful tool for pharmacokinetic studies”, Journal of

    Chromatographic Science, 51, 361-370, 2013.

    139. T.R. Correia, B.P. Antunes, P.H. Castilho, J.C. Nunes, M.T.P. de Amorim, I.C.

    Escobar, J.A. Queiroz, I.J. Correia, A.M. Morão, “A bi-layer electrospun nanofiber

    membrane for plasmid DNA recovery from fermentation broths”, Separation and

    Purification Technology, 112, 20-25, 2013.

    140. A. Palmeira-de-Oliveira, R. Palmeira-de-Oliveira, C. Gaspar, L. Salgueiro, C.

    Cavaleiro, J. Martinez-de-Oliveira, J.A. Queiroz, A.G. Rodrigues, “Association of

    Thymbra capitata essential oil and chitosan (TCCH hydrogel): a putative therapeutic

    tool for the treatment of vulvovaginal candidosis”, Flavour and Fragance Journal, 28,

    354–359, 2013.

  • 141. J.A. Queiroz, E. Gallardo, M. Barroso, “What are the recent advances in forensic

    oral fluid bioanalysis?”, Bioanalysis, 5, 2077-2079, 2013.

    142. A.P. Gomes, J.F. Mano, J.A. Queiroz, I.C. Gouveia, “Layer-by-layer deposition of

    antimicrobial polymers on cellulosic fibers: a new strategy to develop bioactive

    textiles”, Polymers Advanced Technologies, 24, 1005-1010, 2013.

    143. T. Matos, J.A. Queiroz, L. Bulow, “Binding and elution behavior of small

    deoxyribonucleic acid fragments on a strong anion-exchanger multimodal

    chromatography resin”, Journal of Chromatography A, 1302, 40-44, 2013.

    144. R. Martins, J.A. Queiroz, F. Sousa, “New approach in RNA quantification using

    arginine-affinity chromatography: Potential application in eukaryotic and chemically

    synthesized RNA”, Analytical and Bioanalytical Chemistry, 405, 8849-8858, 2013.

    145. M.S. Silva, V.C. Graça, L.V. Reis, P.F. Santos, P. Almeida, J.A. Queiroz, F.

    Sousa, “Protein purification by aminosquarylium cyanine dye-affinity

    chromatography”, Biomedical Chromatography, 27, 1671-1679, 2013.

    146. A. Soares, J.A. Queiroz, F. Sousa, A. Sousa, “Purification of human

    papillomavirus 16 E6/E7 plasmid deoxyribonucleic acid-based vaccine using an

    arginine modified monolithic support”, Journal of Chromatography A, 1320, 72-79,

    2013.

    147. T. Matos, S. Senkbeil, A. Mendonça, J.A. Queiroz, J.P. Kutterc, L. Bulow,

    “Nucleic acid and protein extraction from electropermeabilized E. coli cells on a

    microfluidic chip”, Analyst, 138, 7347-7353, 2013.

    148. F.F. Correia, F.M. Santos, A.Q. Pedro, M.J. Bonifácio, J.A. Queiroz, L.A.

    Passarinha, “Recovery of biological active catechol-O-methyltransferase isoforms from

    Q-sepharose”, Journal of Separation Science, 37, 20-29, 2014.

  • 149. T. Matos, H.-O. Johansson, J.A. Queiroz, L. Bulow, “PCR DNA fragments

    purification using aqueous two-phase systems”, Separation and Purification

    Technology, 122, 144-148, 2014.

    150. P. Pereira, A. Sousa, J.A. Queiroz, I. Correia, A. Figueiras, F. Sousa, “Purification

    of pre-miR-29 by arginine-affinity chromatography”, Journal of Chromatography B,

    951-952, 16-23, 2014.

    151. P. Pereira, A. Sousa, J.A. Queiroz, A. Figueiras, F. Sousa, “New approach for

    purification of pre-miR-29 using lysine-affinity chromatography”, Journal of

    Chromatography A, 1331, 129-132, 2014.

    152. S. Ferreira, C. Júlio, J.A. Queiroz, F.C. Domingues, M. Oleastro, “Molecular

    diagnosis of Arcobacter and Campylobacter in diarrhoeal samples among Portuguese

    patients”, Diagnostic Microbiology and Infectious Disease, 78, 220-225, 2014.

    153. A. Silva-Dias, A. Palmeira-de-Oliveira, I.M. Miranda, J. Branco, L. Cobrado, M.

    Monteiro-Soares, J.A. Queiroz, C. Pina-Vaz, A.G. Rodrigues, “Anti-biofilm activity of

    low-molecular weight chitosan hydrogel against Candida species”, Medical

    Microbiology and Immunology, 203, 25-33, 2014.

    154. D. Costa, A.J.M. Valente, M.G. Miguel, J.A. Queiroz, “Plasmid DNA microgels

    for drug/gene co-delivery: a promising approach for cancer therapy”, Colloids and

    Surfaces A: Physicochemical and Engineering Aspects, 442, 181-190, 2014.

    155. C. Cruz, R. Boto, P. Almeida, J.A. Queiroz, “NMR screening of new carbocyanine

    dyes as ligands for affinity chromatography”, Journal of Molecular Recognition, 27,

    197-204, 2014.

    156. T. Matos, J.A. Queiroz, L. Bulow, “Plasmid DNA purification using a multimodal

    chromatography resin”, Journal of Molecular Recognition, 27, 184-189, 2014.

  • 157. V.M. Gaspar, C.J. Maia, J.A. Queiroz, C. Pichon, I.J. Correia, F. Sousa, “Improved

    minicircle DNA biosynthesis for gene therapy applications", Human Gene Therapy

    Methods, 25, 93-105, 2014.

    158. D. Costa, A.J.M. Valente, M.G. Miguel, J.A. Queiroz, “Plasmid DNA hydrogels

    for biomedical applications”, Advances in Colloid and Interface Science, 205, 257-264,

    2014.

    159. J.C. Nunes, M.T.P. Amorim, I.C. Escobar, J.A. Queiroz, A.M. Morão, “Plasmid

    DNA/RNA separation by ultrafiltration: modeling and application study”, Journal of

    Membrane Science, 463, 1-10, 2014.

    160. S. Ferreira, F. Silva, J.A. Queiroz, M. Oleastro, F.C. Domingues, “Resveratrol

    against Arcobacter butzleri and Arcobacter cryaerophilus: Activity and effect on cellular

    functions”, International Journal of Food Microbiology, 180, 62-68, 2014.

    161. A. Afonso, P. Pereira, J.A. Queiroz, A. Sousa, F. Sousa, “Purification of pre-miR-

    29 by a new O-phospho-L-tyrosine affinity chromatographic strategy optimized using

    design of experiments”, Journal of Chromatography A, 1343, 119-127, 2014.

    162. G.M. Espírito Santo, A.Q. Pedro, D. Oppolzer, M.J. Bonifácio, J.A. Queiroz, F.

    Silva, L.A. Passarinha, “Development of fed-batch profiles for efficient biosynthesis of

    catechol-O-methyltransferase”, Biotechnology Reports, 3, 34-41, 2014.

    163. A.Q. Pedro, R.F. Soares, D. Oppolzer, F.M. Santos, L.A. Rocha, A.M. Gonçalves,

    M.J. Bonifacio, J.A. Queiroz, E. Gallardo, L.A. Passarinha, “An improved HPLC

    method for quantification of metanephrine with coulometric detection”, Journal of

    Chromatography & Separation Techniques, 5, 217, 2014.

    164. A.P. Gomes, J.F. Mano, J.A. Queiroz, I.C. Gouveia, “New biomaterial based on

    cotton with incorporated biomolecules”, Journal of Applied Polymer Science, 131,

    40519, 1-9, 2014.

  • 165. J. Santos, F. Sousa, J.A. Queiroz, D. Costa, “Rhodamine based plasmid DNA

    nanoparticles for mitochondrial gene therapy”, Colloids and Surfaces B: Biointerfaces,

    121, 129-140, 2014.

    166. C. Nunes, A. Sousa, J.C. Nunes, A.M. Morão, F. Sousa, J.A. Queiroz,

    “Supercoiled plasmid DNA purification by integrating membrane technology with a

    monolithic chromatography”, Journal of Separation Science, 37, 1229–1236, 2014.

    167. J.F. Valente, A. Sousa, J.A. Queiroz, F. Sousa, “Selective purification of

    supercoiled p53-encoding pDNA with L-methionine-agarose matrix”, Analytical

    Biochemistry, 459, 61-69, 2014.

    168. A.F. Jozala, L. Novaes, P. Mazzola, L. Oliveira-Nascimento, T. Penna, J.A.

    Teixeira, L. Passarinha, J.A. Queiroz, A.P. Júnior, “Low-cost purification of nisin from

    milk whey to a highly active product”, Food and Bioproducts Processing, in press.

    169. E. Mota, F. Sousa, A. Sousa, J.A. Queiroz, C. Cruz, “Molecular recognition of

    oligonucleotides and plasmid DNA by L-methionine”, Journal of Molecular

    Recognition, in press.

    170. A.S. Rocha, F.M. Santos, J.P. Monteiro, J.P. Castro-de-Sousa, J.A. Queiroz, C.T.

    Tomaz, L.P. Passarinha, “Trends in proteomic analysis of human vitreous humor

    samples”, Electrophoresis, in press.

    171. R. Martins, J.A. Queiroz, F. Sousa, “Ribonucleic acid purification”, Journal of

    Chromatography A, in press.

    172. D. Bicho, A. Sousa, F. Sousa, J.A. Queiroz, C.T. Tomaz., "Effect of

    chromatographic conditions and plasmid DNA size on the dynamic binding capacity of

    a monolithic support", Journal of Separation Science, in press.

    173. A. Sousa, A.M. Almeida, U. Černigoj, F. Sousa, J.A. Queiroz, “Histamine

    monolith versatility to purify supercoiled plasmid DNA from Escherichia coli lysate”,

    Journal of Chromatography A, in press.

  • 174. V.M. Gaspar, C. Gonçalves, D. Melo-Diogo, E.C. Costa, J.A. Queiroz, C. Pichon,

    F. Sousa, I.J. Correia, “Poly (2-ethyl-2-oxazoline)-PLA-g-PEI amphiphilic triblock

    micelles for co-delivery of minicircle DNA and chemotherapeutics”, Journal of

    Controlled Release, in press.

    175. C. Cruz, A. Sousa, E. Mota, F. Sousa, J.A. Queiroz, “Quantitative analysis of

    histamine- and agmatine-DNA interactions using surface plasmon resonance”,

    International Journal of Biological Macromolecules, in press.


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