K01 SCHOOL OF LIFE SCIENCES & CHEMICAL K02 · K01 SCHOOL OF LIFE SCIENCES & CHEMICAL K02 The...

SCHOOLOFLIFESCIENCES&CHEMICALTECHNOLOGY / K01

The School’s niche areas are in fast-evolving fields such as sustainable bio-chemicals, aquaculture and marine biology, molecular diagnostics, environmental science and engineering, urban agriculture and skyrise greening, biopharmaceuticals, bioprocess technology and cancer biology. The School also collaborates actively with leading industry partners, as well as renowned local and overseas research and academic institutions.

LSCT students enjoy a broad-based and flexible education through a curriculum that is reviewed regularly to meet the changing needs of the life sciences and chemical industries. They also benefit from the knowledge and guidance of academic staff who are dynamic, dedicated and experienced professionals.

Students are provided with numerous opportunities to develop attributes in leadership, communication, resilience and community service through co-curricular activities, service learning and overseas programmes.

LSCT graduates are well-prepared for a multitude of career paths and are highly valued by the industry. Many have excelled in their degree and postgraduate studies at local and overseas universities, and made their mark in their chosen fields.

COURSES OFFERED

LSCT offers the following courses:

• Diploma in Biomedical Science (BMS)

• Diploma in Molecular Biotechnology (MBIO)

• Diploma in Pharmacy Science (PHARM)

• Diploma in Veterinary Bioscience (VBS)

• Diploma in Landscape Design & Horticulture (LDH)

• Diploma in Chemical & Biomolecular Engineering (CBE)

• Diploma in Environmental & Water Technology (EWT)

MAJOR ACHIEVEMENTS

Since its establishment, the School has built a track record in research and development (R&D) in areas with industrial and commercial potential, and has successfully bid for competitive research funding from the National Research Foundation, MOE Translational & Innovation Fund, Singapore Totalisator Board and A*STAR. The R&D projects focus on areas that include environmental technology, molecular diagnostics, biopharmaceutical manufacturing, industrial biotechnology, urban agriculture and aquatic science & technology.

The School of Life Sciences & Chemical Technology (LSCT) has grown steadily in strength and reputation to become a premier provider of life sciences and chemical technology education in Singapore. LSCT graduates can look forward to rewarding careers filled with challenges and making a real difference in the lives of many people.

www.np.edu.sg/lsct

LSCTLIFE SCIENCES &SCHOOL OF

CHEMICAL TECHNOLOGY

SCHOOLOFLIFESCIENCES&CHEMICALTECHNOLOGY / K02K01

The Diploma in Chemical & Biomolecular Engineering was successfully re-accredited by the Institution of Chemical Engineers, United Kingdom.

Students and staff continue to achieve stellar performance in the academic and sporting arena, invest heavily in community service projects, make significant contributions through research work and consistently share their discoveries in science and technology in books and international scientific publications.

LSCT graduates continued to excel in 2016:

Further EducationTan You, Julia (BMS2016) is studying and Lim Xiong Chang (BMS2015) will study medicine at NUS Yong Loo Lin School of Medicine while Zenneth Lim Zen Wei (BMS2016) will enter NTU Lee Kong Chian School of Medicine.

Soh Xian Hui (LDH2016) and Tan Jia Xian (LDH2016) are studying Architecture in NUS.

AwardsJean Chia Wei Lin (BMS2016), a Public Service Commission Scholar, received the Lee Kuan Yew STEP Scholarship and is studying Psychology in NUS.

Students from CBE and EWT courses, namely G Mornish, Amirul Hazim B Salleh, Serene Lee Jia Ying, Wei Longtai, Valerie Chan Wen Xuan and Yao Yupeng, were awarded the IES-SG50 Golden Jubilee Scholarship to pursue their engineering endeavors. Andrea Chua Wei Ming, Chelsea Chandani Eliathamby, Oei Yi Ping, Lovy Lim, Ng Wei-Jie Brandan, and Lareina Sng from BMS, MBIO and VBS respectively received the A*STAR Science Award in recognition for their academic performance and passion.

Community Service Students and staff continued to work with Food Bank Singapore, collecting close to 7 tons of food supply to

enrich low-income families’ daily meals in the annual food drive. They also regularly engaged the elderly at the St. John Home for Elderly Persons.

Sports Competing against Asian top athletes, Christy Jeremia Suriadi from EWT came in 1st runner up in the Junior Elite Woman’s Sprint distance race at the 2016 Subic Bay NTT ASTC Triathlon Asian Cup in the Philippines.

Publications Ruther Teo Zheng published a research paper in the Journal of Cell Biology which deepened the scientific community’s knowledge of regulations and control of genes using the common fruit fly as a model organism. His findings add to the repertoire of medical knowledge for patient suffering from genetic diseases.

Nur Atiqah Abdul Rahman and Wong Ting Suen (BMS2014) published a research paper on the impact of micro-organisms on paintings in the International Journal of Scientific Research in Environmental Sciences. Their findings significantly contribute towards art preservation in museums and art galleries.

Mohamed Fauzi Haroon (BIO2006) published his work on “Living bacteria in the Red Sea”, working as a researcher at King Abdullah University of Science and Technology in Saudi Arabia. His discovery is key to understanding the microbial eco-system in the Middle East waters and nutrient recycling for marine organisms.

CompetitionsSofee Al Munawarah Bte Yusoff and Nurul Syafiqah Bte Modh Shed from EWT received a commendation award at the Singapore Junior Water Prize 2016 for design engineering soil media for bioretention systems that will impact water treatment strategy in public waterways.

Learning beyond SingaporeThis year, 50% of our students visited Shanghai and South Korea for immersion programs at different universities. They made industrial-related visits and

strengthened their understanding of the countries’ economy and technology landscapes.

Students also visited University of Western Australia as part of the Overseas Merit Award (Life Sciences) programme. In the programme, students underwent a rigorous training to further heighten their passion for science through specially designed projects that integrate ethical issues, engineering, and the environment.

Others spent their semester breaks on an educational project helping under-privileged children in the remote parts of Cambodia and Vietnam.

Staff Expertise and Achievements Veterinary Bioscience Course Chair, Dr Lee Kim Sung co-authored of the book Chikungunya Virus: Method and Protocols (Methods in Molecular Biology), 1st Edition, April 2016. He wrote a chapter on “Advanced Genetic Methodologies in Tracking Evolution and Spread of the Chikungunya Virus”.

Senior lecturer, Dr Lau Quek Choon actively contributed to the book, Infectious Diseases in Singapore – Past, Present and Future, with the Society of Infectious Diseases Singapore. He also received the 2016 SAC Assessor Award (Gold) from the Singapore Accreditation Council (SAC) in recognition for his contributions to its programmes.

Technology Research and DevelopmentResearch staff secured $4.2 million from several competitive grants such as from the National Research Foundation which is managed by the Prime Minister’s Office. Students thus have the opportunity to embark on ground-breaking projects and discoveries with the school staff.

Service to educationMr Eng Boon Hwee received the Efficiency Medal and Mr Vincent Yik received the Long Service Award at the 2016 National Day Awards in recognition of their lifelong

/ SCHOOLOFLIFESCIENCES&CHEMICALTECHNOLOGYK03

mission in educating youth.

UNIQUE LEARNING EXPERIENCE

Students enjoy a conducive learning environment with well-equipped and up-to-date facilities such as those available in the Cell Culture Research Laboratory, Bio-fuel Research Laboratory, Pharmacy Compounding Studio, Food Science Laboratory, Centre for Biomanufacturing Excellence, Centre for Aquatic Science and Technology and the Animal Holding Unit. LSCT also has extensive teaching laboratories for life sciences, chemical engineering, environmental sciences and technology as well as horticulture and landscape design studios and greenhouses.

LDH students have the opportunity to attend lessons in a classroom set within the lush setting of Clementi Woods Park. This learning facility, known as the Greenhub, is well equipped for indoor lessons and has an outdoor experimental garden. With this real-life setting, our students are even better trained with horticultural knowledge and skills.

EWT students have the unique experience of learning Sustainable Environmental Practices by participating in a 2-week Enhanced Study Trip to Tianjin, South Korea or Taiwan where they gain first-hand knowledge about joint public-private environmental projects between the governments and businesses as well as sustainable environmental practices around the world.

Students will experience e-learning opportunities in their modules. For instance, the “Virtual Pharmacy” was conceptualised and developed by our staff for Year 1 and 2 Pharmacy Science students to hone their work skills in an online pharmacy setting. This allows students to integrate knowledge from several modules through a practice-oriented and role-play fun approach.

Students also gain an enriching global perspective through numerous overseas programmes that will develop them holistically.

STAFF

LSCT academic staff members hold Masters and PhD qualifications and have considerable industrial and research experience. They have expertise in areas such as aquaculture, horticulture, bioprocess and biopharmaceutical technology, biomedical diagnostics and therapeutics, molecular diagnostics, cancer biology, developmental biology, microbiology, drug discovery, gene delivery and vaccine development, transgenic research, veterinary medicine, preclinical studies, surface chemistry and rheology.

LSCT also provides consultancy services and R&D expertise to industries. It has tie-ups with leading names from industry and academia such as Temasek Life Sciences Laboratories, Nestle R&D Centre, Procter& Gamble, Johnson & Johnson Pte Ltd, Sumitomo Chemicals, Genome Institute of Singapore, Institute of Molecular & Cell Biology, National Cancer Centre, National University of Singapore, National Parks Board, National Environment Agency, Agri-Food and Veterinary Authority of Singapore and National Neuroscience Institute. Each year, our staff are also involved in consultancies and training activities with small and medium enterprises (SMEs).

COLLABORATIONS

LSCT’s partnerships with key external organisations provide students with extensive hands-on training and relevant exposure to the working world.

CBE, EWT, and LDH students have the opportunity to undergo a mentorship programme. Through the programme, students will be given increasing exposure to the career pathways and career progression opportunities in their respective industries. Students will also benefit through the sharing of real life and work experiences by their mentors, who are experienced industry practitioners from reputable institutions/ companies.

They include Croda Singapore, Lonza Biologics, National Parks Board, RelianZ Engineering, Sembcorp Industries, Shell Eastern Petroleum, etc.

In partnership with National University Hospital’s (NUH) Department of Pharmacy, PHARM students spend their final year at NUH receiving training and guidance from practising pharmacists and clinicians. Exposure to the comprehensive services and state-of-the-art facilities at NUH, equip students with intensive learning opportunities.

BMS students can choose to join the two-year Integrated Clinical Laboratory Training Programme at NUH at the start of the second year, where they will learn about laboratory techniques and get trained alongside doctors, nurses and medical technologists. They will also receive an additional certification in phlebotomy.

BMS, MBIO and VBS students have opportunities to undertake final year projects in collaboration with A*STAR research institutes and university laboratories. Their internships are with local or overseas research institutions, life sciences companies and veterinary clinics. A partnership with Wildlife Reserves Singapore allows VBS students to be involved in unique research and development, training and co-curricular activities.

Students also have the opportunity to work on collaborative projects with PUB, NEA and Sembcorp. Through the School’s collaboration with the National Parks Board, LDH students conduct their fieldwork in the vibrant outdoors of Singapore Botanic Gardens and Clementi Woods Park. EWT students can also go on local or overseas internships.


The comprehensive curriculum covers the latest in biomedical sciences and medical breakthroughs. These include areas such as cancer biology, infectious diseases, clinical chemistry, drug discovery, immunology, translational medicine and genomics and proteomics.

In their second year, students select either the Biomedical Research or Clinical Laboratory Technology specialisation option. The Biomedical Research option exposes students to the latest developments in biomedical sciences. The Clinical Laboratory Technology option enables students to be trained at the National University Hospital (NUH) alongside doctors, nurses and medical technologists to diagnose diseases.

ENTRY REQUIREMENTS

To be eligible for consideration, candidates must have the following GCE ‘O’ Level examination (or equivalent) results.

You must also fulfil the aggregate computation requirements.

* Candidates with English as a second language (EL2) must have attained a minimum grade of 6.

Subject ‘O’ Level Grade

English Language*

Mathematics (Elementary/Additional)

Science (with Physics, Chemistry or

Biology component)

or Biotechnology

or Fundamentals of Electronics

1-7

1-6

1-6

CAREER PROSPECTS

Singapore is Asia’s fastest-growing biomedical hub with world-class research institutes, corporate laboratories and public hospitals. The boom in the biomedical industry will drive the demand for skilled personnel in this field. BMS graduates will be equipped with domain knowledge and skills that will allow them to embark on rewarding and exciting careers in biomedical and life sciences research and development, healthcare, drug discovery and biopharmaceutical industries. They will also have a range of transferable skills valued by many employers.

Sandy Xiao (BMS 2008) worked as a Public Health Officer at Tan Tock Seng Hospital and was subsequently awarded the National Health Group Merit Healthcare Scholarship to study Dietetics in Australia. She is currently a dietitian at Tan Tock Seng Hospital.

Many of our graduates have also progressed to degree studies and on to do their PhDs and advanced to senior positions in companies.

ACCREDITATION FOR FURTHER STUDIES

BMS graduates can pursue a wide range of degree programmes such as biological science, medicine, dentistry, chemistry, laboratory medicine, medical technology, allied health professions such as occupational therapy, physiotherapy, speech therapy, medical social work and nutrition and dietetics, bioengineering, education, architecture, business, business administration, psychology and social science.

To date, six out of the eight LSCT graduates who gained direct entry into Yong Loo Lin School of Medicine at the National University of Singapore were from the BMS course. In 2013, Amy Chia (BMS 2013) was the first Ngee Ann graduate to score a place in NUS’ Faculty of Dentistry. Zenneth Lim Zen Wei was the first graduate to be accepted into the NTU Lee Kong Chian School of Medicine in 2016.

DIPLOMA IN BIOMEDICAL SCIENCE (BMS)

The Diploma in Biomedical Science (BMS) is the most established biomedical science diploma programme in Singapore.

BMSBIOMEDICALDIPLOMA IN

SCIENCE


In fact, about 60 per cent of BMS graduates enrol into the National University of Singapore (NUS), Nanyang Technological University (NTU), Singapore Management University (SMU) and Singapore Institute of Technology (SIT) every year.

Top universities overseas also welcome our graduates with exemptions of up to two years. They include: • Australian National University (Australia)• Murdoch University (Australia)• Queensland University of Technology (Australia)• RMIT University (Australia)• University of Adelaide (Australia)• University of Melbourne (Australia)• University of New South Wales (Australia)• University of Queensland (Australia)• University of Sydney (Australia)• University of Technology Sydney (Australia)• University of Western Australia (Australia)• University of Leeds (UK)• University of Manchester (UK) • University of Edinburgh (UK) • University of Dundee (UK) • University of Liverpool (UK)• Queen’s University Belfast (UK) • University of Auckland (New Zealand)

You can also deepen your skills and further yourcareer by enrolling in the following post-diplomaqualifications offered by Ngee Ann Polytechnic:

• Advanced Diploma in Medical and Pharmaceutical Technology

• Specialist Diploma in Analytical Science*• Specialist Diploma in Veterinary Clinical Practice*

*Offered under SkillsFuture Earn and Learn programme

COURSE CURRICULUM

Module Name Credit Units Module Name Credit Units

YEAR 1Level 1.1 (24.5 hours per week) Career & Professional Preparation I 1.5Inorganic & Physical Chemistry 6Innovation Toolkit ^ 4Mathematics 5Microbiology 6Sports & Wellness ^ 2

Level 1.2 (25 hours per week) Anatomy and Physiology 4Biostatistics 3Cell Biology and Genetics 6Critical Thinking and Communication ^ 4Good Laboratory Practice 2Organic Chemistry 6

At the end of their first year, students will select one of two specialisation options: Biomedical Research or Clinical Laboratory Technology.


Biomedical Research Specialisation Option*

YEAR 2Level 2.1 (27 hours per week) Cell Culture & Tissue Applications 5Immunology & Immunological Techniques 6Medical Biochemistry 6Medical Microbiology 6Career & Professional Preparation II 2Interdisciplinary Studies (IS) elective ^ 2

Level 2.2 (25 hours per week) Advanced Organic Chemistry 4Analytical & Separation Chemistry 6Applied Biostatistics 4Molecular Biology 6Elective (Choose 1): - Biopharmaceutical Analysis 4 - Pathology 4 - Toxicology and Pharmacology 4

YEAR 3Level 3.1 (24 hours per week) Genomics & Proteomics 6Bioinformatics 2Capstone Project 8World Issues: A Singapore Perspective ^ 2Interdisciplinary Studies (IS) elective ^ 2Electives (Choose 1):- Translational Medicine 4- Drug Discovery & Clinical Trials 4- Pharmaceutical Analysis 4- Nutrition & Dietetic Science 4 Level 3.2 (24 hours per week) Four-month Internship 16Capstone Project 8


Clinical Laboratory Technology Specialisation Option*

YEAR 2Level 2.1 (27 hours per week) Advanced Topics in Biomedical Science 4Laboratory Techniques in Clinical Chemistry 7Laboratory Techniques in Clinical Haematology 7Laboratory Techniquesin Clinical Microbiology 7Career & Professional Preparation II 2

Level 2.2 (25 hours per week) Clinical Haematology 1 7Clinical Microbiology 1 7Clinical Chemistry 1 7Applied Biostatistics 4

Notes: ^ For more details on Interdisciplinary Studies (IS) electives, please log on to www.np.edu.sg/is/

IS Modules The School of Interdisciplinary Studies (IS) delivers a broad-based curriculum, which nurtures a new generation of professionals with multidisciplinary skills and an innovative and entrepreneurial spirit to meet the challenges of a knowledge economy. IS offers both prescribed modules and electives to challenge boundaries. Prescribed modules develop students’ competencies in core areas such as Communication, Innovation and Enterprise, Culture and Communication, and Personal Mastery and Development, while elective modules provide insights into Arts and Humanities, Business, Design, and Science and Technology.

COURSE CURRICULUM

Module Name Credit Units

YEAR 3Level 3.1 (18 hours per week) Bioinformatics 2Integrative Module 6Laboratory Endocrinology 3Laboratory Management 3Molecular Diagnostics 4 Level 3.2 (33 hours per week) Clinical Chemistry 2 7Clinical Haematology 2 7Clinical Microbiology 2 7Genomics and Proteomics 2Capstone Project 8World Issues: A Singapore Perspective ^ 2

*Conducted in collaboration with National University Hospital. Students will receive additional certification in phlebotomy.

COURSE MODULES

LEVEL 1.1 Inorganic & Physical Chemistry The module covers the structure of matter, chemical bonding, orbital hybridisation, thermochemistry, chemical equilibria, kinetics, electrochemistry and redox reactions, transition metal chemistry, chemistry of solutions, including acids, bases and buffers.

Microbiology This module introduces a basic understanding of microorganisms and techniques in microbiology. Topics include cell structure and function, classification, viruses and fungi, nutrition, growth and regulation, environmental factors affecting growth, microscopy, staining, size measurement, cell enumeration, media preparation, isolation and cultivation of pure cultures.

Mathematics This module provides students with a fundamental and analytical knowledge of Mathematics essential for the

study of life sciences. The module is designed to equip students with the necessary mathematical techniques to solve biological and chemical problems, as well as to carry out analytical studies in their future work. Topics include analytical geometry, logarithmic functions, integration, differentiation and differential equations.

Career & Professional Preparation I This module is part of the Education and Career Guidance framework to provide students with the tools and resources necessary for their career and/or further education. In this first module, students will undergo personal discovery and exploration of industry and career prospects. Students will learn on how they can plan and set achievable goals in preparation for their future. Students will also learn the importance of passion and professionalism, and basic teamwork and interpersonal skills.

LEVEL 1.2Biostatistics This module is designed to provide students with basic statistical skills to analyse and interpret simple biological, pre-clinical and clinical data. The basic statistical skills covered are descriptive statistics, data distribution, set sample size, measurement of central tendency, scatter diagram, cluster analysis, and simple linear correlation and regression analysis for linear data. The presentation of data in graphical forms using Microsoft Excel covers selection and preparation of different types of graphs, how to write titles and legends, and interpretation of results and draw conclusions.

Cell Biology & Genetics This module explores mammalian cells, tissue and organ systems. Topics include the fundamental chemicals of life, structure and function of cells and organelles, membrane trafficking, cell cycle and division, study of genes, genetic variation and heredity.

Good Laboratory Practice Good laboratory practice comprises a set of principles that helps to define and standardise the planning,



performance monitoring, recording, reporting, and archiving processes within research institutions and commercial testing laboratories. The module covers standard operating procedures, quality assurance programme, receipt and handling of samples, monitoring performance of the study, reporting of study results, and retention of records. Compliance to GLP regulations will also be covered.

Organic Chemistry In this module, students are introduced to the chemistry of hydrocarbons, alcohols, amines, aldehydes, ketones, carboxylic acids and their derivatives. The properties and chemical reactivity of these compounds in relation to the application of chemistry in life sciences will also be discussed.

Anatomy & Physiology This module equips students with an understanding of the basic principles of homeostatic mechanisms and the cardiovascular, respiratory, renal, gastrointestinal, neuromuscular, endocrine and reproductive physiological systems that exist in the human body. It also covers the basic skeletal system and anatomy.

At the end of their first year, students will select either Biomedical Research or Clinical Laboratory Technology.

LEVEL 2.1 Cell Culture & Tissue Applications This module is a detailed study of the techniques and applications of animal cell culture. Topics include the preparation of media, cell viability checks, passaging of inherent cells, cryopreservation, cloning and mycoplasma assays. Tissue engineering and rapid prototyping are also taught.

Medical BiochemistryThis module introduces fundamental biochemical


BIOMEDICAL RESEARCH SPECIALISATION OPTION

concepts and practices. The subject integrates biological and chemical concepts as they relate to biochemistry and biochemical disorders. The module prepares students to work in biochemical industries and research institutions, and covers three major areas of protein chemistry, enzymology and metabolism.

Immunology and Immunological TechniquesThis module introduces the fundamentals of immunology and provides an understanding of how the immune system functions as an integrated defense system against disease. Topics include an overview of the innate and adaptive immunity, humoral and cell mediated immunity, immunisation and vaccination. Also covered are the applications of immunological techniques in research and clinical diagnostic laboratories. Medical Microbiology This module is a continuation of the first-year microbiology module. The module covers how microorganisms spread and cause disease in humans, properties of the infectious agents, principles of the laboratory diagnosis, and management of infection including the strategies for prevention of infection.

Career & Professional Preparation IIThis module is part of the Education and Career Guidance framework to provide students with the tools and resources necessary for their further career and/or education. In this module, students will explore basic job search strategies, practise the writing of effective resumes and cover letters, and learn interview skills. Students will also learn professional and intercultural communication skills to prepare them for a dynamic and diverse workplace.

LEVEL 2.2 Applied Biostatistics This module covers advanced statistical skills to analyse and interpret a wide range of biological, pre-clinical and clinical data, and preparation of data for scientific presentation. The statistical skills covered are biological experiment design, hypothesis testing, quantitative data

analysis by parametric and non-parametric methods, qualitative data analysis by Chi-square and Fisher tests, and simple correlation & regression analysis for non-linear data. The scientific presentation section covers how to organise data, prepare and incorporate statistical results on graphs and interpretation of results.

Analytical & Separation Chemistry This module covers various instruments which are used in analytical chemistry/biochemistry with the emphasis on their practical use. Students will study the workings of the UV-Vis, HPLC (including IEX, gel filtration, affinity chromatography), capillary and gel electrophoresis. This module will also cover the interpretation of mass spectrometry as applied to small molecules and proteins; proton and 13C-NMR, infra-red spectroscopy in the structural elucidation of organic molecules.

Advanced Organic Chemistry This module covers basic organic reaction mechanisms like nucleophilic substitution (SN2 and SN1 mechanisms), elimination (E1 and E2 mechanisms), electrophilic addition and electrophilic aromatic substitution, nucleophilic substitution mechanisms e.g. esterification, reactions of enols and enolates e.g. alkylation, aldol, Claisen reaction. This module will also cover basic strategies in organic synthesis.

Molecular Biology This module covers the fundamentals of molecular biology. Topics include DNA structure and replication, mRNA transcription, protein synthesis, regulation of gene expression in microorganisms, gene mutation and DNA repair mechanisms. In the area of recombinant DNA technology and molecular techniques, students will learn about the isolation of genomic and plasmid DNA, polymerase chain reaction, insertion of target DNA into cloning vector, transformation of E.coli competent cells, identification of recombinant clones, isolation of total RNA and gel electrophoresis. Students will be introduced to basic bioinformatics software for analysis of nucleic acid and protein sequences.

SCHOOLOFLIFESCIENCES&CHEMICALTECHNOLOGY / K08DIPLOMA IN BIOMEDICAL SCIENCE (BMS)

Biopharmaceutical AnalysisThis module is designed to equip students with knowledge and molecular techniques that are used to analyse raw materials and biological products. Topics include an overview on biologics production using microbial and mammalian systems, detection of adventitious agents in biological products using quantitative PCR (qPCR), endotoxin and pyrogen testing, bioburden test, and detection of residual host cell proteins using enzyme linked immunosorbent assay (HCP-ELISA). An overview on pharmaceutical law and regulatory landscape will also be covered.

Toxicology & Pharmacology This module covers the basic principles of pharmacology, pharmacodynamics, pharmacokinetics (absorption, distribution, metabolism, and elimination), the major drug classes and an introduction to toxicology. Students will also be introduced to the various methods in determining drug toxicity and efficacy in vitro drug testing.

PathologyThis module covers an introduction to pathology, the causes and mechanisms of diseases, characterization and diagnosis of diseases, and treatment and prevention of diseases.

LEVEL 3.1Genomics & ProteomicsThis module provides an insight into the fields of proteomics and genomics Students will study the functions of genes and their interaction within a genome, the human genome project, genetically modified organisms and gene therapy, protein expression with emphasis on the structure and functions of proteins and methods of purification and analyses of proteins and applications of proteomics.

BioinformaticsThis module equips students with essential bioinformatics computational skills. Topics include an overview of biological informatics, microarray, protein structure prediction and structural databases, finding conserved motifs and patterns in protein using online databases, and applications of software tools and resources in gene expression data analysis.

Capstone Project Students will complete a final year research project under the guidance of an academic staff or industry mentor. The Capstone Project can cover any of the key areas in life science research including Molecular Biosciences, Industrial Biotechnology, Food Technology, Aquatic Science & Technology, Environmental Technology and Urban Horticulture and Greenscape. Students will be able to integrate and apply the knowledge and skills learned from the course. They will be involved in report writing as well as presenting the outcomes of the project in poster and oral presentations. The Capstone Project will further strengthen their writing and communication skills as well as analytical and problem solving skills, thus preparing them for the industry or further studies.

Translational Medicine This module builds on the previous modules taken in the first and second year of the Biomedical Science course. Upon completion of this module, students will be able to appreciate the difference between basic and clinical research and apply the knowledge learnt in conducting translation research.

Drug Discovery & Clinical Trials This module will introduce students to the drug discovery processes, the relationship between activity and functional group chemistry, chemistry of drugs and drug systems. The module also covers the role, composition and authority of Institutional Review Board (IRB), the phases of clinical trials, informed consent, ethical issues in clinical trials, and compliance to regulations.

Pharmaceutical Analysis This module is designed to introduce students to the chemical analysis of raw materials and final pharmaceutical products. It also covers the sample preparation and separation techniques as well as analytical methods. Topics include chemical analysis on active pharmaceutical ingredients (APIs), detection of heavy metals, stability test, purity test, sample preparation using various extraction methods, limit test, and test for extractables and leachables.

Nutrition & Dietetic Science This module provides students with a basic understanding of nutritional and dietetic concepts, including the role of micro and macronutrients in the diet and their effects on health. Principles of clinical nutrition and dietary requirements for special medical conditions and at different life stages will also be covered. Students will also learn to evaluate the evidence behind the use of common nutraceuticals and functional foods for health benefits as well as the regulations associated with the sales and marketing of such therapies.

LEVEL 3.2 Four-month Internship Students will undertake a four-month internship and project, giving them opportunities to relate and apply the knowledge acquired in classrooms to work situations and in research. They will be attached to research institutes and companies in various industries such as the pharmaceuticals, healthcare and bioinformatics sectors. Students will also have the opportunity to go on overseas internships.

Capstone Project Students will complete a final year research project under the guidance of an academic staff or industry mentor. The Capstone Project can cover any of the key areas in life science research including Molecular Biosciences, Industrial Biotechnology, Food Technology, Aquatic Science & Technology, Environmental Technology and Urban Horticulture and Greenscape. Students will be able to integrate

ELECTIVES

/ SCHOOLOFLIFESCIENCES&CHEMICALTECHNOLOGYK09DIPLOMA IN BIOMEDICAL SCIENCE (BMS)

and apply the knowledge and skills learned from the course. They will be involved in report writing as well as presenting the outcomes of the project in poster and oral presentations. The Capstone Project will further strengthen their writing and communication skills as well as analytical and problem solving skills, thus preparing them for the industry or further studies.

Students undergo a two-year Integrated Clinical Laboratory Training Programme (ICLTP) conducted in collaboration with the National University Hospital. Students will receive additional certification in phlebotomy.

LEVEL 2.1 Advanced Topics in Biomedical Science This module covers basic immunology, metabolic biochemistry and molecular biology. In immunology, the coverage is on the components and functions of the immune system. Metabolic biochemistry introduces fundamental concepts in enzymology and carbohydrate metabolism. Molecular biology will cover introduction to prokaryotic and eukaryotic molecular biology, gene manipulations and protein expressions.

Laboratory Techniques in Clinical Chemistry This module covers the principles of protein separation techniques, immuno-nepholometry, immuno-turbidimetric analysis, chromatographic techniques, therapeutic drug analyses, immunochemical techniques, blood gas analysis and diagnostic procedures for hormonal testing.

Laboratory Techniques in Clinical Haematology This is an introductory module with emphasis on basic instrumentation and diagnostic procedure performed in Blood Bank and Haematology laboratory. Students will learn about the principles, procedures and interpretation of manual and automated analyzer results.

CLINICAL LABORATORY TECHNOLOGY SPECIALISATION OPTION

Laboratory Techniques in Clinical MicrobiologyThis module aims to demonstrate the daily routines of a microbiology laboratory serving a public hospital. Students should take note of the essential skills such as aseptic techniques, medium preparation, urinalysis, diagnostics methods for parasitology and virology.

Career & Professional Preparation IIThis module is part of the Education and Career Guidance framework to provide students with the tools and resources necessary for their further career and/or education. In this module, students will explore basic job search strategies, practice writing of effective resumes and cover letters, and learn interview skills. Students will also learn professional and intercultural communication skills to prepare them for a dynamic and diverse workplace.

LEVEL 2.2 Applied Biostatistics This module covers advanced statistical skills to analyse and interpret a wide range of biological, pre-clinical and clinical data, and preparation of data for scientific presentation. The statistical skills covered are biological experiment design, hypothesis testing, quantitative data analysis by parametric and non-parametric methods, qualitative data analysis by Chi-square and Fisher tests, and simple correlation & regression analysis for non-linear data. The scientific presentation section covers how to organise data, prepare and incorporate statistical results on graphs and interpretation of results.

Clinical Chemistry 1 This module focuses on basic biochemical pathways such as glucose metabolism and diseases, water and ion metabolism, liver metabolism, plasma proteins as well as their related laboratory tests. Basic pathology and pathogenesis of diseases include cell injury, cell death, inflammation and neoplasia will also be covered.

Clinical Haematology 1 This module covers the theory and principle of morphologic alterations in blood cells, various blood cell disorders, pediatrics heamatology and antigen-antibody

reactions as applied to blood-banking. Emphasis is given to cell-typing, cross-matching, compatibility problems and HLA-typing for organ and bone marrow transplants.

Clinical Microbiology 1 This module aims to provide students with more in-depth microbiological knowledge. Students will also learn about tuberculosis diagnostic tests and non-culture based investigations such as serology. In terms of theoretical knowledge, students are expected to be familiar with pathogen laboratory characteristics and identification, as well as relating specific pathogens to clinically important diseases.

LEVEL 3.1 Bioinformatics This module equips students with essential bioinformatics computational skills. Topics include an overview of biological informatics, microarray, protein structure prediction and structural databases, finding conserved motifs and patterns in protein using online databases, and applications of software tools and resources in gene expression data analysis

Integrative Module This module will cover the basic phlebotomy course focusing on the techniques, and theories of phlebotomy as well as the basic skills to interact with the patients. Besides, polyclinic attachment is also covered under this module.

Laboratory Endocrinology This module introduces the physiology and pathogenesis of endocrine disorders, as well as laboratory testing related to endocrine disorders. This provides important background and understanding to use of laboratory tests in diagnosis, monitoring and prognosticating endocrine diseases.

Laboratory Management This module covers an overview of important aspects of laboratory management, including costing, material

SCHOOLOFLIFESCIENCES&CHEMICALTECHNOLOGY / K10DIPLOMA IN BIOMEDICAL SCIENCE (BMS)

management, project management, infectious disease management, information technology and the laboratory, quality management and laboratory laws and accreditation. Molecular Diagnostics This module explores basic molecular biology techniques used in the diagnostic laboratory. Topics include the molecular testing of inherited and infectious diseases, haematological disorders, and cancer. Related laboratory tests are covered.

LEVEL 3.2 Genomics & Proteomics This module aims to provide students with a theoretical knowledge of advances in the field of genomics and proteomics. These include the Human Genome Project, an appreciation of high-throughput platforms in genomics and proteomics, and applications in the understanding of, diagnosis and treatment of diseases.

Clinical Chemistry 2 This module covers advanced topics in clinical chemistry such as acid base physiology and disorders, lipid metabolism, calcium regulation, organ system review and diseases (gastrointestinal tract, cardiac markers, infectious disease testing, autoimmune diseases).

Clinical Haematology 2 This module covers the normal and pathophysiology of bone marrow, haematological malignancies such as leukemias, lymphoma, myeloproliferative disorders and non-malignancies disorders such as anemia, myelodysplasia, coagulation disorders. Advanced haematological investigation using Flow Cytometry and conventional methods as well as Fluorescence In-situ Hybridisation (FISH) cytogenetics will also be covered.

Clinical Microbiology 2 This module focuses on less frequently encountered infectious diseases which are associated with significant morbidity and mortality. Students will learn more

about processing blood culture and cerebrospinal fluid specimens, susceptibility testing methods, non-culture based diagnostic tests, infections associated with bacteria, fungi, viruses and parasites along with an introduction to the antibiotic classes.

Capstone ProjectStudents will complete a final year research project under the guidance of an academic staff or industry mentor. The Capstone Project can cover any of the key areas in life science research including Molecular Biosciences, Industrial Biotechnology, Food Technology, Aquatic Science & Technology, Environmental Technology and Urban Horticulture and Greenscape. Students will be able to integrate and apply the knowledge and skills learned from the course. They will be involved in report writing as well as presenting the outcomes of the project in poster and oral presentations. The Capstone Project will further strengthen their writing and communication skills as well as analytical and problem solving skills, thus preparing them for the industry or further studies.


CBE is the only course in Singapore that integrates biological and chemical sciences with engineering concepts. It encompasses chemical processing, pharmaceuticals, environmental science and engineering as well as life sciences, making it a very versatile course. Hands-on training is strongly featured throughout the entire curriculum.

First-year modules introduce students to concepts from organic and biological chemistry, inorganic and physical chemistry, chemical and biochemical engineering, and biomolecular science. Second-year modules offer an in-depth study of biopharmaceutical technology, chemical engineering processes, analytical chemistry, engineering materials, heat and mass transfer processes, and reaction engineering.

In the final year, students can choose either the General Chemical Engineering specialisation option that provides students with exposure to the well-established chemical industry, or the Pharma & Biopharmaceutical specialisation option that allows them to capitalise on the vast and rapidly growing pharma and biomedical science industries. Both options cover modules on process engineering design, process instrumentation and control as well as unit operations.

In addition, third year students can opt for either the Industry Track that provides practical training through an internship with the industry, or the Research Track that provides research training through an internship with research institutions.

ENTRY REQUIREMENTS




CAREER PROSPECTS

There is increasing demand for multi-disciplined professionals. CBE graduates have the foundation and flexibility to enter various careers in a myriad of industries - from chemical, petrochemical, biochemical, biotechnology and pharmaceutical to food & beverage, electronics, environment and sustainability-related.

CBE graduates enjoy good employment prospects as technologists, technical officers, project supervisors or assistant engineers in a design, operations, process, control or maintenance unit; laboratory technologists, pollution control or plant safety officers in a quality control unit; or as sales engineers.


English Language*



Biology component)

or Biotechnology

or Computer Studies

or Design & Technology


1-7

1-6

1-6

The Diploma in Chemical & Biomolecular Engineering (CBE) is designed to meet the growing needs of the petroleum, petrochemical, chemical, pharmaceutical and life sciences industries. Graduates will be empowered to bridge the gaps between these different disciplines.

CBECHEMICAL & DIPLOMA IN

BIOMOLECULARENGINEERING



CBE is fully accredited by the Institution of Chemical Engineers (IChemE), UK. CBE graduates can pursue a wide range of degree programmes offered by National University of Singapore, Nanyang Technological University, Singapore Management University, Singapore University of Technology and Design and the Singapore Institute of Technology. Graduates can apply for programmes in Chemical Engineering, Environmental Engineering, Material Sciences, Chemistry, Physics,Bioengineering and Biological Science in addition to a wide range of business and other non-engineering courses.

Overseas universities which offer CBE graduates up to two years’ exemption from their Chemical Engineering courses include:

• University of Adelaide (Australia) • University of Melbourne (Australia) • University of Queensland (Australia) • University of New South Wales (Australia) • University of Adelaide (Australia) • University of Western Australia (Australia) • University of Birmingham (UK) • Loughborough University (UK) • Newcastle University (UK)


• Advanced Diploma in Medical and Pharmaceutical Technology • Specialist Diploma in Analytical Sciences*

* Offered under SkillsFuture Earn and Learn Programme

COURSE CURRICULUM


YEAR 1Level 1.1 (26.5 hours per week) Engineering Mathematics 1 6Introduction to Chemical &Biochemical EngineeringOrganic & Biological Chemistry 8Career & Professional Preparation I 1.5Innovation Toolkit ^ 4Sports & Wellness ^ 2

Level 1.2 (27.5 hours per week) Biomolecular Science 4.5Engineering Mathematics 2 6Inorganic & Physical Chemistry 8Thermodynamics 5Critical Thinking & Communication ^ 4

YEAR 3Level 3.1 (28 hours per week) General Chemical Engineering Specialisation OptionIndustrial Chemical Processes 1.5Petrochemical Technology 1.5Process Engineering Design 8Process Instrumentation & Control 5Unit Operations 5World Issues: A Singapore Perspective ^ 2Interdisciplinary Studies (IS) elective ^ 2 Pharma & Biopharmaceutical Specialisation OptionBiopharmaceutical Quality Control 1.5Current Good Manufacturing Practice 1.5Pharmaceutical Engineering Laboratories 3Process Engineering Design 8Process Instrumentation & Control 5Unit Operations for Pharmaceutical Processes 5 World Issues: A Singapore Perspective ^ 2Interdisciplinary Studies (IS) elective ^ 2 Level 3.2 Industry Track Industrial Internship 22

Research Track Research Internship 22

YEAR 2Level 2.1 (26 hours per week) Analytical Chemistry 3Biopharmaceutical Production 5Chemical Engineering Laboratory 2.1 3Engineering Mathematics 3 4Reaction Engineering 4Transfer Processes – Fluid Flow 3Career and Professional Preparation II 2Interdisciplinary Studies (IS) elective ^ 2

Level 2.2 (23.5 hours per week) Analysis of Chemical Engineering Processes Chemical Engineering Laboratory 2.2 3Engineering Materials 2Environmental Technology 4Occupational Health & Safety 2Transfer Processes – Heat & Mass 4Interdisciplinary Studies (IS) elective ^ 2

DIPLOMA IN CHEMICAL & BIOMOLECULAR ENGINEERING (CBE)

6.5

5


COURSE MODULES

LEVEL 1.1 Engineering Mathematics 1 Students will study mathematical subjects relevant to engineering applications. This module provides them with the necessary mathematical skills required in other engineering subjects. Topics include algebra, exponential and logarithmic functions, trigonometry, combination and permutation, plane analytical geometry, binomial expansion, determinants and matrices.

Introduction to Chemical & Biochemical Engineering Students are introduced to basic chemical engineering concepts and applications, for example, units and dimensions, material balance calculations, reaction stoichiometry, reaction engineering, and fluid mechanics. Upon completion of this module, students will be able to undertake basic chemical engineering calculations. The module also provides hands-on practice of AutoCAD in engineering drafting to allow students to appreciate the use of computer software in



the engineering field. Organic & Biological Chemistry This practical-oriented module is designed to give students an introduction to organic and biological chemistry. Students will be introduced to the chemistry of hydrocarbons, alcohols, amines, carboxylic acids and their derivatives. The structure, function and chemical reactions of carbohydrates, lipids, proteins, nucleic acids, enzymes and coenzymes are also covered.

LEVEL 1.2 Biomolecular Science This module introduces students to cell biology, microorganisms and techniques in microbiology. Students will learn about cell structure, cell membrane, microbial growth and nutrition, cellular transport mechanisms, DNA replication, transcription and translation, mycology, virology and aseptic techniques.

Engineering Mathematics 2 A continuation of the Engineering Mathematics 1 module, topics in this module include complex numbers, statistical techniques, differentiation, integration, further integration techniques and numerical methods for evaluating definite integrals. Emphasis is placed on their applications in solving engineering-related problems. A mathematical software package is also used to solve these problems.

Inorganic & Physical Chemistry This module covers the principles of physical chemistry as well as the reactions and properties of inorganic compounds. Students will study the structure of matter, chemical bonding, chemical calculations, electrochemistry and redox reaction, chemical equilibria, ionic equilibria, chemical kinetics, thermochemistry, transition metal chemistry and chemistry of solutions, including acids and bases.

Thermodynamics Students will study the fundamental concepts of thermodynamics and fluid mechanics. Topics include

the first and second laws of thermodynamics, properties of liquids and vapours, non-flow processes and steady flow processes with steam and perfect gases. The concepts of pressure, pressure head, and pressure measurement will also be discussed. Career & Professional Preparation IThis module is part of the Education and Career Guidance framework to provide students with the tools and resources necessary for their career and/or further education. In this first module, students will undergo personal discovery and exploration of industry and career prospects. Students will learn how to plan and set achievable goals in preparation for their future. Students will also learn the importance of passion and professionalism, along with basic teamwork and interpersonal skills.

LEVEL 2.1 Analytical Chemistry This module teaches students some common separation and characterisation instruments and instrumental techniques used in the laboratory, as well as provide hands-on opportunity for them. These techniques include UV-visible spectrophotometry (UV-Vis), gas liquid chromatography (GLC), high performance liquid chromatography (HPLC) and Atomic Absorption Spectroscopy (AAS).

Biopharmaceutical Production This module provides students with a working knowledge of all aspects of the manufacturing of biologics products. This module will cover various aspects of upstream and downstream manufacturing including media and buffer batching, cell banking, microbial and animal cell culture, bioreactor technology cell harvesting, chromatography, and fill and finish processes.

Chemical Engineering Laboratory 2.1 This module integrates the practical aspects of Reaction Engineering and Transfer Processes - Fluid Flow modules. In addition, students will also explore basic



electrical concepts for the determination of efficiency of common chemical engineering equipment, such as pumps and compressors.

Engineering Mathematics 3 Building upon the materials covered in the earlier two modules on engineering mathematics, this module provides students with an adequate knowledge of mathematics to solve problems encountered in their future work. Topics include vector algebra, first and second order differential equations and their applications, Laplace transform technique and its applications, and regression analysis. Students will also use a mathematical software package to solve these problems.

Reaction Engineering Students will focus on reactor design principles. Topics include reactor kinetics, analysis of batch reactors, continuous stirred tank reactors and plug flow reactors. It also covers topics in material balance calculations as well as aspects of the design, construction and operation of chemical and biological reactors. Examples from the petrochemical, chemical, environmental and biotechnology industries are used to reinforce lecture materials.

Transfer Processes - Fluid Flow Students are introduced to fluid dynamics in this module. Topics include energies of liquids in motion, flow in pipes, general principles of pumps and system characteristics compressors, and flow measurement.

Career & Professional Preparation IIThis module is part of the Education and Career Guidance framework to provide students with the tools and resources necessary for their further career and/or education. In this module, students will explore basic job search strategies, practise writing effective resumes and cover letters, and learn interview skills. Students will also learn professional and intercultural communication skills to prepare them for a dynamic and diverse workplace.

LEVEL 2.2 Analysis of Chemical Engineering Processes In this module, students will study the fundamental principles of flow diagram analysis, including both mass and energy balances, and the use of a process flow-sheeting package.

Chemical Engineering Laboratory 2.2 This module integrates the practical aspects of Environmental Technology and Transfer Processes - Heat and Mass modules.

Engineering Materials In this module, students will study the properties of materials commonly used in industries and gain an understanding of the basic requirements to carry out the proper selection of materials. Topics include the classification of materials, properties of materials, metals, alloy and polymeric materials, corrosion and degradation of materials.

Environmental Technology This module introduces students to environmental problems and their impact. Students will study the various methods, applications and equipment in solving and preventing environmental problems, specifically in the areas of air and water pollution, and the management of industrial wastes.

Occupational Health & Safety This module gives students an understanding of biological, chemical and physical hazards, ergonomics, radiation, and management of dangerous and toxic goods. It also includes an overview of occupational health and safety legislation as part of a basic knowledge of industrial safety.

Transfer Processes - Heat & Mass This module explores the mechanisms of heat transfer (conduction, convection and radiation), and introduces the importance of heat exchangers in chemical engineering processes. The fundamentals of mass transfer are also covered, giving a deeper

understanding of key chemical engineering processes such as evaporation and condensation, distillation, and other extraction and separation techniques.

LEVEL 3.1 Chemical Engineering Laboratories 3.1 This module integrates the practical aspects of Level 3.1 modules of Unit Operations, and Process Instrumentation & Control.

Industrial Chemical Processes In this module, students will acquire a basic understanding of the chemical industry through comprehensive analyses of key chemical processes. The key manufacturing processes in the pharmaceutical industry are also covered. The module also highlights the importance and relevance of sustainability and green engineering in the chemical industry.

Petrochemical Technology In this module, students are introduced to the petrochemical industry. Topics include an overview of the industry and its importance to Singapore and the region, its key products, raw materials, intermediate and product flows, economics of petrochemical processing and key petrochemical processes.

Process Engineering Design Students will deal with process flow sheets, piping and instrumentation diagrams, process and mechanical design of equipment, cost and evaluation of projects, materials of construction, safety and loss prevention. A practical design project is used to reinforce theory.

Process Instrumentation & Control This module gives students a broad introduction to the principles and applications of instruments in process industries such as instrumentation for temperature, flow, level and pressure measurements. Other topics include

GENERAL CHEMICAL ENGINEERING SPECIALISATION OPTION



the fundamental concepts of feedback control, system dynamics and stability, PID control modes, controller tuning, multivariable control strategies, control valve sizing, and an introduction to digital control techniques and computer control of chemical processes.

Unit Operations This module focuses on solvent extraction, crystallisation, drying, evaporation, distillation, digestion, absorption, adsorption and material handling as applied to unit operations in various sectors such as the petroleum, petrochemical, chemical and pharmaceutical industries.

Biopharmaceutical Quality Control This module will introduce the functions of a quality control entity in a pharmaceutical and biopharmaceutical manufacturing facility, as well as the various raw material, in-process, product and stability testing methodologies and specifications.

Current Good Manufacturing Practice Students will cover the US Food and Drug Administration’s current Good Manufacturing Practice (GMP) regulations for pharmaceutical and related products. Various aspects, such as attributes of materials, labelling, materials in process, finished pharmaceuticals, manufacturing validation, quality control, personnel and facilities are covered.

Pharmaceutical Engineering Laboratories This module integrates the practical aspects of Level 3.1 modules of Unit Operations, and Process Instrumentation & Control.

Process Engineering Design Students will deal with process flow sheets, piping and instrumentation diagrams, process and mechanical design of equipment, cost and evaluation of projects,

materials of construction, safety and loss prevention. A practical design project is used to reinforce theory.

Process Instrumentation & Control This module gives students a broad introduction to the principles and applications of instruments in process industries such as instrumentation for temperature, level and pressure measurements. Other topics include the fundamental concepts of feedback control, system dynamics and stability, PID control modes, controller tuning, multivariable control strategies, control valve sizing, and an introduction to digital control techniques and computer control of chemical processes.

Unit Operations for Pharmaceutical Processes This module covers topics such as solvent extraction, crystallisation, drying, evaporation, distillation, digestion, absorption, adsorption and material handling as applied to unit operations in various sectors such as the petroleum, petrochemical, chemical and pharmaceutical industries.

LEVEL 3.2 (Industry Track) Industrial Internship Students will do an internship and project which will give them opportunities to apply the knowledge acquiredin classrooms to real-world work situations. They will be attached to companies in various industries such as the petrochemicals, specialty chemicals, and pharma- or biopharmaceutical sectors.

LEVEL 3.2 (Research Track) Research Internship Students will be introduced to basic research skills, which include literature review, laboratory safety, project management, and statistical analysis of laboratory data, followed by opportunities to undertake a scientific research project. The projects will be carried out in-house or at external research institutions, which include overseas institutions.

PHARMA & BIOPHAMACEUTICAL SPECIALISATION OPTION





CAREER PROSPECTS The Singapore government has set aside part of a $2 billion research fund to drive the growth of the environmental and water technology industry. This is expected to result in increased employment opportunities in the future.

Equipped with broad-based and practice-oriented knowledge and skills, EWT graduates are well-placed for careers with government agencies, multinational corporations and private organisations. They can work as environmental technologists, assistant engineers, research officers, water and wastewater treatment specialists, environmental health officers, assistant biodiversity officers, workplace health and safety officers, project engineers, planning executives, technical executives as well as marketing executives for environment-related equipment and products.


Local and overseas universities accept EWT graduates into related Bachelor degree programmes in Environmental Engineering, Civil Engineering, Environmental Studies, Environmental Sciences and Environmental Management, with exemptions and advanced standing. They include:

• Nanyang Technological University • National University of Singapore• Singapore Management University• Singapore University for Technology and Design• Singapore Institute of Technology• Murdoch University (Australia) • University of Adelaide (Australia) • University of New South Wales (Australia)

This course focuses on environmental challenges and finding effective solutions to protect the environment and natural resources. Jointly developed with PUB (Singapore’s National Water Agency), EWT trains students to become specialists in addressing global concerns such as water and marine pollution, air pollution, global warming, ozone depletion, and improper handling of hazardous waste. Students benefit from a firm grounding in the key areas of water technology, waste management and resource conservation, pollution monitoring and control and environmental management, as well as health and safety.

Fully supported by PUB and National Environment Agency (NEA), and endorsed by the Ministry of Manpower, EWT opens doors for graduates in the fast growing environmental and water technology industry. These partnerships allow students to gain real-life exposure to the industry prior to graduation.

Outstanding students can apply for PUB’s bond-free scholarships and the Building & Construction Authority (BCA)-Industry scholarships and sponsorships, with prospects of employment upon graduation.

ENTRY REQUIREMENTS


More than one in six people around the world do not have access to safe drinking water and each year, water-related diseases contribute to four million deaths amongst children. Climate change and food security are imminent problems facing our planet. If you are passionate about the environment and water resources, then our Diploma in Environmental & Water Technology (EWT) will fulfil your career dreams.

EWTENVIRONMENTAL &DIPLOMA IN

WATER TECNOLGY


English Language



Biology component)

or Biotechnology

or Computer Studies



1-7

1-6

1-6

DIPLOMA IN ENVIRONMENTAL & WATER TECHNOLOGY (EWT)


• University of Queensland (Australia)• University of Western Australia (Australia)• University of Birmingham (UK)• University of Manchester (UK) • University of Newcastle (UK)


• Specialist Diploma in Analytical Science* • Specialist Diploma in Sustainable Facilities

Management*


COURSE CURRICULUM


YEAR 1Level 1.1 (30 hours per week) Computer Aided Design 3Engineering Mathematics 1 6Environmental Microbiology & Biotechnology 3.5 Organic & Biological Chemistry 6Noise Monitoring & Control 4Career & Professional Preparation I 1.5Innovation Toolkit ^ 4Sports & Wellness ^ 2

Level 1.2 (26.5 hours per week) Engineering Mathematics 2 6Environmental Health & Biology 3.5Global Environmental Issues 2Hydraulics 5Inorganic & Physical Chemistry 6Critical Thinking & Communication ^ 4

YEAR 3Level 3.1 (24.5 hours per week) Environmental Innovation & Research 8Environmental Management System 3Industrial Wastewater & Membrane Technology 5.5 Water Reclamation Technology 4World Issues: A Singapore Perspective ^ 2Interdisciplinary Studies (IS) elective ^ 2

Level 3.2 (20 hours per week)Four-month Internship 16Sustainable Environment Practices 4

YEAR 2Level 2.1 (24.5 hours per week) Engineering Mathematics 3 4Solid & Hazardous Waste Management 3Water & Environmental Chemistry 5Water & Marine Pollution 3Water Supply Technology & Design 5.5Interdisciplinary Studies (IS) elective^ 2Career & Professional Preparation II 2

Level 2.2 (23 hours per week) ABC Waters Management 4Air Quality Monitoring & Control 5Civil Engineering Fundamentals 6Environmental Process Systems 3Workplace Safety & Health 3Interdisciplinary Studies (IS) elective^ 2





COURSE MODULES

LEVEL 1.1Computer Aided Design This module provides students with the principles and techniques of preparing computer-aided design (CAD) drawings in environmental related applications and construction projects. Students will be exposed to applications of AUTOCAD in environmental project work including noise mapping, sewerage and drainage diagrams, process plant diagrams and site plans. Students will also be trained to interpret and extract information from CAD drawings and prepare CAD drawings according to CP 83. Emphasis will be placed on preparing CAD drawings accurately so that information can be used electronically. AutoCAD is used in this module as it is widely adopted in the AEC industry.

Engineering Mathematics 1 Students will study mathematical subjects relevant to engineering applications. This module provides them with the necessary mathematical skills required in other engineering subjects. Topics include algebra, exponential and logarithmic functions, trigonometry, combination and permutation, plane analytical geometry, binomial expansion, determinants and matrices.

Environmental Microbiology & Biotechnology Sustainable development calls for newer approaches towards developmental activities and technologies, so that eco-health is preserved alongside conservation of invaluable natural resources. Environmental biotechnology is a tool that provides such an approach for understanding, managing, preserving and restoring environmental quality. Students will be exposed to the fundamentals of microbiology and biotechnological methodologies that can be suitably utilised to assess the well-being of ecosystems, transform pollutants to harmless substances, generate biodegradable materials from renewable sources, and develop eco-friendly manufacturing and disposal processes.

Applications, including recent developments in the field of microbiology and biotechnology in aspects relating to the environment will be covered.

Organic & Biological Chemistry This practical-oriented module is designed to give students an introduction to organic and biological chemistry. Students will be introduced to the chemistry of hydrocarbons, alcohols, amines, carboxylic acids and their derivatives. The structure, function and chemical reactions of carbohydrates, lipids, proteins, nucleic acids, enzymes and coenzymes are also covered.

Noise Monitoring & Control Singapore’s rapid economic growth towards an industrialised and urbanised society coupled with an affluent population has resulted in a greater need to control noise in the general environment. The control of noise pollution is essential in all aspects of work and students will be taught the fundamentals of how noise pollution arises, health impacts of noise, measurement and monitoring of noise levels, preventive and control measures and local environmental legislation. The module provides for two WSQ recognised certifications under Competency unit of Monitor Noise and Vibration (Competency Code: OH-PH-501C-1) and Competency unit of Control Noise and Vibration (Competency Code: OH-PH-502C-1), if students qualify based on the WSQ assessment plan.

Career & Professional Preparation I This module is part of the Education and Career Guidance framework to provide students with the tools and resources necessary for their career and/or further education. In this first module, students will undergo personal discovery and exploration of industry and career prospects. Students will learn how to plan and set achievable goals in preparation for their future. Students will also learn the importance of passion and professionalism, and basic teamwork and interpersonal skills.

LEVEL 1.2 Engineering Mathematics 2 A continuation of the Engineering Mathematics 1 module, topics in this module include complex numbers, statistical techniques, differentiation, integration, further integration techniques and numerical methods for evaluating definite integrals. Emphasis is placed on their applications in solving engineering-related problems. A mathematical software package is also used to solve these problems.

Environmental Health & Biology The module introduces students to the field of environmental health science and provides a foundation for further studies and application in environmental law, safety and health management. Students will be trained in the areas of microbiology, parasitology, entomology, vector control, epidemiology and communicable disease control, human biology and food hygiene.

Global Environmental Issues With globalisation, the growth of the human population and technological advances, pressures on the planet’s natural systems are becoming increasingly intense and complex. This module discusses current global environmental issues and the interaction between human activities, resources, and the environment. Contributing social, political and economic factors will be covered. Mitigation measures such as research, conservation, role of media, volunteer work and technology will be emphasised. The aim of this module is to promote greater environmental awareness and nurture social responsibility towards the environment.

Hydraulics Students will learn the basic hydraulic principles and concepts which are essential for the study of water and wastewater treatment technologies. Students will be exposed to properties of fluids, manometers, hydrostatics and fundamental principles of fluid flow. Head losses in pipeline, design of pipeline, flow measurements and pipe network analysis will be covered. Students will also learn the open channel



flow, the design of surface water drainage systems and pumping pipeline systems.

Inorganic & Physical Chemistry This module covers the principles of physical chemistry as well as the reactions and properties of inorganic compounds. Students will study the structure of matter, chemical bonding, chemical calculations, electrochemistry and redox reactions, chemical equilibria, ionic equilibria, chemical kinetics, thermochemistry, transition metal chemistry and chemistry of solutions, including acids and bases.

LEVEL 2.1 Engineering Mathematics 3 Building upon the materials covered in Engineering Mathematics 1 and 2, this module provides students with an adequate knowledge of mathematics to solve problems encountered in their future work. Topics include vector algebra, first and second order differential equations and their applications, Laplace Transform technique and its applications, and Regression Analysis. Students will also use a mathematical software package to solve these problems.

Solid & Hazardous Waste Management In this module, students will be taught how solid and hazardous waste is generated, methods of collection, handling, treatment, disposal of waste and related pollution impacts. Concepts of waste minimisation such as recycling, reuse, reduction and waste exchange will be highlighted as effective tools for sustainable waste management. Issues in hazardous waste with emphasis on biomedical waste generation, collection and treatment will be addressed. Local legislation for solid and hazardous waste will be explained in relation to the overall waste management system.

Water & Environmental Chemistry This practice-oriented module introduces students to key aspects of environmental and water chemistry for application in pollution control, resource recovery and water and wastewater treatment. Students will

have hands-on exposure to practical aspects of environmental chemistry, quantitative measurements and analysis of solid wastes, water and wastewater. Principles of measurement, instrumentation and analysis are emphasised using an application-oriented approach. Water & Marine Pollution Students will be given an overview of water pollution and the impact of pollution on different types of waterbodies like rivers, lakes and seas. They will learn the characteristics of polluted waterbodies, types of waste streams and indicators of water pollution, waste disposal into river and the self-purification of river systems. Effects of pollution in lakes and reservoirs, marine pollution, sources and impacts of pollution in sea and oil spill control at sea and beaches will also be covered.

Water Supply Technology & Design This module introduces the concepts of water treatment technologies for treating raw water from various sources. The focus in this module is to impart knowledge on the conventional water treatment technologies. The topics covered include pre-treatment, sedimentation, filtration and disinfection techniques for the treatment of potable water. Adverse effects of hardness and hardness treatment using chemical methods and the use of ion-exchange processes are covered in detail. Practical problems associated with the operation and maintenance of water treatment plants including mechanical & electrical equipment and possible solutions for these problems will be emphasised.

Career & Professional Preparation IIThis module is part of the Education and Career Guidance framework to provide students with the tools and resources necessary for their further career and/or education. In this module, students will explore basic job search strategies, practice writing of effective resumes and cover letters, and learn interview skills. Students will also learn professional and intercultural communication skills to prepare them for a dynamic and

diverse workplace.

LEVEL 2.2 ABC Waters Management Singapore has an extensive network of waterways and waterbodies allowing efficient stormwater management. This module provides an introduction to the Active, Beautiful and Clean (ABC) Waters Programme as part of the initiative to remake Singapore into a vibrant ‘City of Gardens and Water’. Students will be taught about the role of ABC Waters design features in keeping Singapore’s waterways and waterbodies clean by retaining and treating stormwater close to the source. Other topics covered include design concepts of sedimentation basins, vegetated swales and bioretention systems.

Air Quality Monitoring & Control Monitoring and control of both outdoor and indoor air pollution are important aspects of environmental management. Students are taught the fundamentals of how air pollution arises, types of pollutants, and their environmental and health impacts. Dispersion modelling, indoor air quality audit, sampling and monitoring of pollutants, techniques of identification of pollutants, preventive and control measures, local environmental legislation and guidelines on air quality including PSI will be introduced.

Civil Engineering Fundamentals This module explores the fundamental principles and practices of civil engineering. It provides students with an understanding of the main types of civil engineering structures and construction processes. It also covers the theory of statics and mechanics of materials, with applications to a range of environmental engineering projects.

Environmental Process Systems Students will focus on reactor design principles. Topics include reactor kinetics, analysis of batch reactors, continuous stirred tank reactors and plug flow reactors. It also covers material balance calculations as well



as aspects of the design, construction and operation of chemical and biological reactors, process control systems and diagrams. Examples from the water, wastewater and environmental industry will be used to reinforce the content.

Workplace Safety & Health The module covers the relevant legislation and standards pertaining to workplace safety and health. Students will be taught to identify the various types of workplace hazards and the means of protection and control against these hazards. The topics will include risk assessment and control, safety management systems, job safety analysis, accident reporting and investigation. Students will be issued WSHC recognized bizSAFE Level 2 certificates upon completion of this module.

LEVEL 3.1 Environmental Innovation & Research In this module, students are expected to integrate the knowledge they have gained in the earlier semesters to undertake an environmental project on a related topic in the field of water, environmental science and technology.

Environmental Management Systems Students will learn the application of concepts and principles in environmental management. Topics covered include the fundamentals of environmental impact assessment (EIA), environmental baseline studies (EBS), environmental management systems (EMS), ISO 14001, ISO 50001, environmental auditing and renewable energy.

Industrial Wastewater & Membrane Technology Characteristics of industrial wastewater vary with the industrial process. Treatment methodology adopted varies with the type of wastewater. Membrane applications are taking an edge as a treatment option. Topics that will be covered include unit processes and treatment technologies applicable to industrial wastewater treatment and specific industrial wastewater case studies. Students will be introduced to membrane

science and applications in environmental engineering. Membrane applications in water reclamation, recycling and reuse including desalination technology will be taught. Case studies will be used to illustrate specific industrial applications.

Water Reclamation Technology The module introduces students to sewage characteristics, sewer design and maintenance and unit operations in a conventional wastewater treatment plant. The module will also cover the fundamentals of sewage collection systems for domestic wastewater, wastewater treatment technologies, monitoring and operation of wastewater treatment systems and the code of practice relevant to sewerage and wastewater treatment. Students will also learn about sludge treatment and disposal technologies. Emerging technologies in water reclamation and water recycling will be emphasised.

LEVEL 3.2 Four-month Internship In this module, students will be attached to organisations for a period of four months. This is to prepare them for future employment in their particular discipline of study. During their internship, students will undertake projects and tasks assigned by the organisations. This allows them the opportunity to take initiative as well as to develop self-confidence, and interpersonal and adaptation skills.

Sustainable Environment Practices This module covers the integration of sustainable practices in various aspects of the environment - namely air quality, water resources and quality, noise & waste management, resource efficiency, renewable energy, ecosystem restoration and heritage conservation, using a model eco-city. Students will have first-hand exposure to a practical and integrated approach to the implementation of the various solutions covered in previous modules.



Leveraging a strong partnership with the National Parks Board (NParks), LDH students are able to undertake much of their practical training, field visits and outdoor lessons at the Singapore Botanic Gardens and other parks. In addition, one of Singapore’s idyllic parks, Clementi Woods Park, has been developed as a “Learning Park” for LDH students, serving as an outdoor classroom where students can engage in experiential learning in a real park setting.

Students will develop a strong understanding of plant taxonomy, plant anatomy, plant biochemistry and physiology, plant pathology, plant genetics and soil science. They will learn how to apply this basic knowledge in modules covering turf management, plant nutrition, hydroponics, horticultural engineering, park and leisure management, and nursery management. They will also learn how plants are affected by their environment and in turn influence both the natural and human environment. This knowledge of plant science is integrated with extensive training in the principles and practices of landscape design. Key landscape design modules cover topics in digital graphics, computer aided drafting, softscape design and landscape design.

LDH students also undertake projects with government bodies and private companies to develop innovative designs that are attractive, easily maintained and co-exist with Singapore’s natural heritage and urban environment. LDH graduates are well-equipped with the expertise to create thriving landscapes to suit different environmental conditions, urban lifestyles and green spaces.

ENTRY REQUIREMENTS


You must have also sat for a Science or Art / Higher Art or Design & Technology or Food & Nutrition or a relevant OSIE / Applied Subject and fulfil the aggregate computation requirements.


CAREER PROSPECTS

With the anticipated growth of the horticultural and landscaping industries, LDH graduates will find ready employment as horticulturists, technologists, nursery supervisors, landscape project executives, landscape designers, park officers, or golf course maintenance officers in the varied horticulture, landscape, facilities management, and leisure and recreation industries.


LDH graduates can enjoy up to two years of exemption in relevant degree courses in horticulture, plant science, agriculture, biological science, botany, environmental science, landscape architecture, architecture, turf


English Language*



Biology component)

or Biotechnology

or Design Studies



Any one other subject

1-7

1-7

1-6

1-6

A unique hybrid of landscape design, plant science and horticulture, the Diploma in Landscape Design & Horticulture (LDH) is the only course of its kind in Singapore offered at a tertiary level.

LDHLANDSCAPE DESIGNDIPLOMA IN

& HORTICULTURE


management and business management offered by local and overseas universities, including:

• National University of Singapore • Nanyang Technological University• Singapore Management University • Lincoln University (New Zealand) • University of Manchester (UK) • University of Melbourne (Australia) • University of New South Wales (Australia) • University of Queensland (Australia) • University of Georgia (USA)

You can enrol in many relevant certification courses thatare offered by the Centre for Urban Greenery andEcology (CUGE) to further develop your expertise inthe landscape industry. There are also relevantprogrammes organised by the National Parks Board(NParks) and the Singapore Institute of LandscapeArchitects (SILA) that you can join to stay current withindustry needs.

COURSE CURRICULUM


YEAR 1Level 1.1 (25.5 hours per week) Plant Anatomy & Morphology 5Taxonomy & Plant Identification 5CAD & Graphic Applications 5Floristry & Interiorscapes 3Career & Professional Preparation I 1.5Innovation Toolkit ^ 4Sports & Wellness ^ 2

Level 1.2 (25 hours per week) Chemistry 4.5Soil Science & Plant Nutrition 6Urban Ecology & Conservation 2.5Landscape Design Communication 1 3Landscape Studio 1 – Design Fundamentals Communication & Contemporary Issues ^ 4


YEAR 2Level 2.1 (28 hours per week) Plant Biochemistry & Physiology 6Plant Pathology & Entomology 5Horticulture & Turf Management 5Plant Identification 2 2Hardscape Design 4Softscape Design 4Interdisciplinary Studies (IS) elective ^ 2

Level 2.2 (26.5 hours per week) Arboriculture 3.5Genetics & Plant Breeding 6Propagation & Nursery Management 5Landscape Design Communication 2 3Landscape Studio 2 – Design Process 5Career & Professional Preparation II 2Interdisciplinary Studies (IS) elective ^ 2



DIPLOMA IN LANDSCAPE DESIGN & HORTICULTURE (LDH)

5

YEAR 3Level 3.1 (25.5 hours per week) Urban Horticulture Technology 5Landscape Studio 3 – Independent Projects Leisure & Park Management 2.5Landscape Project Management 3Project (choose one): - Landscape Design Track - Horticultural Research Track World Issues: A Singapore Perspective ^ 2Interdisciplinary Studies (IS) elective ^ 2 Level 3.2 Internship 22

6

5


COURSE MODULES LEVEL 1.1Plant Anatomy & Morphology This module explores the structural and functional features of plant cells, types of cells and tissues, anatomy and morphology of roots, stems and leaves, and the anatomical development of seeds. Other topics include differences between monocots and dicots, flower structure and plant reproductive cycle.

Taxonomy & Plant Identification This module surveys the principles of plant taxonomy, the relationship among plants, and the classification and biology of algae, fungi, bryophytes, gymnosperms and angiosperms. Other topics include the identification, use, origin and cultural requirements of trees, shrubs, vines and ground covers used for horticultural practices. The emphasis is on common landscape plants used in Singapore.

CAD & Graphic Applications Students will learn the use of computer aided drafting (CAD) and industry-standard graphic software for drafting and design. Topics include drafting in CAD, image editing in Adobe Photoshop, 3D modelling and drawing in SketchUp. Students will gain hands-on practice to create plans, sections and perspectives for landscape drafting and design presentations.

Floristry & Interiorscapes In this module, students will come to appreciate the finer points of basic flower designs and the proper handling of fresh flowers and foliage, as well as the use of potted plants and hydroculture plants in interiorscapes.

Career & Professional Preparation I This module is part of the Education and Career Guidance framework to provide students with the tools and resources necessary for their career and/or further education. In this first module, students will undergo personal discovery and exploration of industry and career prospects. Students will learn how to plan

and set achievable goals in preparation for their future. Students will also learn the importance of passion and professionalism, and basic teamwork and interpersonal skills.

LEVEL 1.2 Chemistry In this module, students will study the basic concepts of chemistry, including the nature, properties, and transformations of matter; stoichiometry and equilibria of chemical reactions; acids and bases; redox reactions; and the fundamentals of organic chemistry.

Soil Science & Plant Nutrition This module covers the fundamentals of soil science, types of growing media, mineral nutrients, soil environment, soilless culture and plant growth in hydroponics systems. Topics include soil formation, soil properties, soil chemical processes, soil fertility, soil pH and nutrient availability, nutrient cycle, soil biology, nutrients in media (soil and soilless), and their uptake, functions, deficiency symptoms and management. Students will learn to use MS Excel to manage and present their data.

Urban Ecology & Conservation This module covers aspects of sustainable environmental management, biodiversity and its conservation, successions, water management, environmental pollution, and discusses how plants are used to restore habitats and enhance the biodiversity in an urban environment.

Landscape Design Communication 1 Students will learn and apply techniques to produce landscape drawings manually and to communicate their designs through these graphics and plant symbols. Topics will include drafting and rendering techniques, lettering conventions in creating landscape plans, sections, elevations and sketching using freehand representation.

Landscape Studio 1 – Design Fundamentals This module introduces the design fundamentals of space creation and visualisation, two- and three-dimensional designs and their application to simple designs. Students are given an overview of professional concerns and responsibilities to use land in an efficient and attractive manner.

LEVEL 2.1 Plant Biochemistry & Physiology This module examines the molecular basis of living processes in plants, metabolism of carbohydrates, plant growth regulators, and environmental and plant stress physiology. Topics include comparative physiological and biochemical processes during growth, maturation, ripening and senescence in fruits, vegetables and flowers in relation to changes to quality and storage life.

Plant Pathology & Entomology This module explores various plant pathogens and diseases as well as their classification and morphology. Topics covered include the biology of bacteria, fungi, nematodes and viruses attacking economic crops; etiology and the control of plant bacterial diseases; the biology of insect pests of horticultural plants; and the application of an integrated pest management system.

Horticulture & Turf Management Students will learn topics on site preparation, planting and maintenance of turf and shrubs, drafting of maintenance schedule and horticultural management. Through fieldwork, students will demonstrate their competence in planting, forking, weeding, mowing and shrub pruning. Topics on types of media used, application of fertilizers and pesticides, mulching, turf establishment and its cultural practices are also covered.

Plant Identification 2 In this module, students will learn an additional 100 plants commonly used in the horticulture and landscaping industry in Singapore. Characteristics of plants from selected plant families will also be studied.



Hardscape Design In this module, students will be introduced to materials used for landscape design, and designing and detailing hardscape elements as an extension of hardscape design and as a means of conveying design intent. Students will apply CAD techniques to prepare hardscape working drawings.

Softscape Design This module covers planting design and documentation for different scales of landscape. Topics include the recognition of the visual and ecological characteristics of plants used in landscape design and the basic principles of planting design. Students will apply CAD techniques to prepare softscape plans and planting plans. They will be introduced to bill of quantities, plant specifications and quantifying plants.

LEVEL 2.2 Arboriculture This module outlines the aims and objectives of an urban forest, leading to an understanding of the value of non-commodity trees in our society. It addresses the theoretical and practical aspects of arboriculture in a city setting with emphasis on the selection, establishment, and maintenance of trees. Basic field machinery and safety precautions are also included.

Genetics & Plant Breeding This module explores the organisation and expression of nuclear and plastid genomes of plants. Topics include the transcriptional regulation and structure of plant genes, gene regulation during plant development and techniques in molecular plant biology for plant research, genetics and breeding of tropical fruit and nut crops, and the classification, culture, cytogenetics and breeding of orchids (orchidology).

Propagation & Nursery Management This module focuses on plant propagation using seeds, different plant parts, plant tissue culture techniques and nursery management. Topics include sexual and asexual propagation techniques, propagation media, plant

growth management, nursery facility planning and work organisation, irrigation systems, nursery operations and management practices.

Landscape Design Communication 2 Students will apply the skills and techniques learned in CAD & Graphic Applications, to digitally plan, draw and communicate their landscape designs. Students will further advance their presentation techniques and develop progressive skills in visual communication and digital representation in landscape design.

Landscape Studio 2 - Design Process This module introduces landscape design from around the world, including historic landscapes and gardens, urban plazas and pedestrian areas, as well as parks and infrastructure. Topics include the arrangement of buildings, circulation, and other landscape design elements, as well as the development of landscape design processes as applied to small-scale projects.


LEVEL 3.1 Urban Horticulture Technology This module introduces current technologies used in the landscape and horticulture industries. Topics include introduction to structural materials, horticultural machinery and tools, irrigation systems and greenhouse management. Planting technologies such as hydroponic operations, vertical farming and greenroof and wall systems will also be covered.

Landscape Studio 3 - Independent Projects In this module, students will undertake individual projects

that involve the entire landscape design process, addressing various aspects of landscape design taught in the first and second year.

Leisure & Park Management This module examines the philosophy, history, psychology, science and development in leisure and park management. It will also cover the principles, practices and economics of such management and some contemporary issues on recreation and leisure. Site visits will enable students to integrate theory with practice.

Landscape Project Management This module covers concepts of project management within the horticulture industry, work planning, cost analysis and risk management. Other topics include construction management, cost estimates and measurements, horticultural contract specifications, work supervision and schedules. Students will use project management software and analyse case studies.

Project Students will work in groups and undertake developmental projects in an area that is of interest to them, either in horticultural research or landscape design, under the supervision of a staff member. In the course of their projects, students will acquire knowledge in literature research and gain technical expertise that will prepare them for working in the industry. They will submit a final year report and present their project through oral presentations.

LEVEL 3.2 Internship In this 22-week programme, students will be attached to private companies or government bodies. They will be exposed to the rigours of the industry in a real-time environment, and will receive valuable on-the-job training in areas of landscape implementation, cut flower retail, nursery management, turf management and horticulture management.



The course curriculum is built on core disciplines such as chemistry, biochemistry, microbiology, molecular biology, biostatistics, cell culture, genomics, proteomics and bioinformatics.

In the second and third year, students can select specific elective modules to fulfil one of three options. The Biopharmaceutical option focuses on discovery, development and manufacturing of biopharmaceuticals. In the Forensic Science option, students will learn how science is used to solve crimes. The Food Science option focuses on food chemistry and processing, food safety and manufacturing of food products.

MBIO is the most established life science diploma programme in Singapore. Students will gain invaluable experience from diverse industry collaborations. Final-year students have the opportunity to take on research projects while undertaking their internship at the R&D laboratories of local universities, research institutes and life science companies.

ENTRY REQUIREMENTS





English Language



Biology component)

or Biotechnology


1-7

1-6

1-6

CAREER PROSPECTS

MBIO graduates have achieved success in a broad range of careers. They are highly sought-after by the biotechnology, biomedical, food and agrotechnology, environmental technology, and pharmaceutical and healthcare industries. The applied nature of the curriculum gives our graduates an edge when they pursue careers in Singapore’s rapidly developing biopharmaceutical industry. A number of MBIO graduates have already received EDB-sponsored overseas training in biopharmaceutical manufacturing.

MBIO graduates can look forward to rewarding careers in research and development with world renowned local institutions such as the Temasek Life Sciences Laboratory, Genome Institute of Singapore, Institute of Molecular and Cell Biology, National Cancer Centre, National Neuroscience Institute and the National University of Singapore. Many of our graduates have completed their PhDs and hold senior positions in companies overseas such as in USA, Spain, Switzerland and Japan.

Dr Eyleen Goh, who graduated in 1994, received an A*STAR PhD scholarship and is now an assistant professor at Duke NUS Graduate Medical School while Drs Chris Sim and Tan Kaeling are senior researchers at Harvard Medical School in USA.


MBIO graduates can pursue a wide range of degree programmes offered by National University of Singapore, Nanyang Technological University and Singapore Management University. They can take up degrees in biological science, chemistry, medicine, chemical engineering, bioengineering, education, arts, architecture, dentistry or business.

In 2007, Soong Junwei was one of two LSCT graduates who were the first polytechnic graduates to be accepted directly into the MBBS degree programme offered by

The Diploma in Molecular Biotechnology (MBIO) provides students with a sound scientific foundation in modern biological sciences leading to careers and further studies in a diverse range of areas such as research, biopharmaceutical manufacturing, chemistry, medicine, pharmacy, engineering, aquaculture, marine biology, and plant science.

MBIOMOLECULARDIPLOMA IN

BIOTECHNOLOGY


the Yong Loo Lin School of Medicine at the National University of Singapore. To date, at least 10 LSCT graduates have gained admission to medical schools in Singapore and overseas.

MBIO is internationally recognised, with graduates receiving one or two years of exemptions from three and four-year degree courses respectively. Overseas universities which accept MBIO graduates include:

• Australian National University (Australia)• University of Melbourne (Australia)• University of Queensland (Australia)• Monash University (Australia)• University of Western Australia (Australia)• University of Sydney (Australia)• Murdoch University (Australia)• University of Technology Sydney (Australia)• University of Glasgow (UK)• University College London (UK)• University of Manchester (UK)• University of Dundee (UK)• Queen’s University Belfast (UK)• University of Auckland (New Zealand)

You can also deepen your skills and further your careerby enrolling in the following post-diploma coursesoffered by Ngee Ann Polytechnic:

• Advanced Diploma in Medical and Pharmaceutical Technology

• Specialist Diploma in Analytical Sciences*• Specialist Diploma in Veterinary Clinical Practice*



Level 1.2 (25 hours per week) Biostatistics 3Cell Biology & Genetics 6Good Laboratory Practice 2Organic Chemistry 6Anatomy & Physiology 4Critical Thinking & Communication ^ 4

Level 3.2 (24 hours per week) Four-month Internship 16Capstone Project 8

Students will take a specific combination of Year 2 and Year 3 electives to fulfil a particular option.

Biopharmaceutical Specialisation Option• Biopharmaceutical Processing (Year 2)• Biomanufacturing Practices (Year 3)

Forensic Science Specialisation Option• Forensic Science (Year 2)• Forensic Chemistry (Year 3)

Food Science Specialisation Option• Food Science & Technology (Year 2)• Food Processing & Safety (Year 3)

YEAR 2Level 2.1 (26 hours per week) Applied Microbiology 6Biochemistry 6Instrumentation & Analytical Chemistry 6Career & Professional Preparation II 2Interdisciplinary Studies (IS) elective ^ 2Elective (Choose 1): - Aquaculture & Marine Biology 4 - Food Science & Technology 4 - Forensic Science 4 - Biopharmaceutical Processing 4

Level 2.2 (27 hours per week) Applied Biostatistics 4Advanced Organic Chemistry 4Molecular Biology 6Immunology 6Cell Culture & Bioprocess Engineering 5Interdisciplinary Studies (IS) elective ^ 2

DIPLOMA IN MOLECULAR BIOTECHNOLOGY (MBIO)

COURSE CURRICULUM


YEAR 1Level 1.1 (24.5 hours per week) Inorganic & Physical Chemistry 6Mathematics 5Microbiology 6Career & Professional Preparation I 1.5Innovation Toolkit ^ 4Sports & Wellness ^ 2

YEAR 3Level 3.1 (24 hours per week) Bioinformatics 2Genomics & Proteomics 6World Issues: A Singapore Perspective ^ 2Interdisciplinary Studies (IS) elective ^ 2Capstone Project 8Elective (Choose 1): - Biomanufacturing Practices 4 - Drug Discovery & Clinical Trials 4 - Food Processing & Safety 4 - Forensic Chemistry 4 - Nutrition & Dietetic Science 4


COURSE MODULES

LEVEL 1.1Inorganic & Physical Chemistry The module covers the structure of matter, chemical bonding, thermochemistry, chemical equilibria, kinetics, electrochemistry and redox reactions, transition metal chemistry, chemistry of solutions, including acids, bases and buffers.

Mathematics This module provides students with a fundamental and analytical knowledge of mathematics, essential for the study of life sciences. The module is designed to equip students with the necessary mathematical techniques to solve biological and chemical problems, as well as to carry out analytical studies in their future work. Topics include analytical geometry, integration, differentiation and differential equations.

Microbiology This module introduces a basic understanding of microorganisms and techniques in microbiology.

Topics include cell structure and function, classification, viruses and fungi, nutrition, growth and regulation, environmental factors affecting growth, microscopy, staining, size measurement, cell enumeration, media preparation, isolation and cultivation of pure cultures.

Career & Professional Preparation I This module is part of the Education and Career Guidance framework to provide students with the tools and resources necessary for their career and/or further education. In this first module, students will undergo personal discovery and exploration of industry and career prospects. Students will learn how to plan and set achievable goals in preparation for their future. Students will also learn the importance of passion and professionalism, and basic teamwork and interpersonal skills.

LEVEL 1.2 Biostatistics This module is designed to provide students with basic statistical skills to analyse and interpret simple biological, pre-clinical and clinical data. The basic statistical skills covered include descriptive statistics, data distribution, set sample size, measurement of central tendency, scatter diagram, cluster analysis, simple linear correlation and regression analysis for linear data. The presentation of data in graphical forms using Microsoft Excel covers selection and preparation of different types of graphs, how to write titles and legends and interpretation of results.

Cell Biology & Genetics This module explores mammalian cells, tissue and organ systems. Topics include the fundamental chemicals of life, structure and function of cells and organelles, cell cycle and division, study of genes, genetic variation and heredity.

Good Laboratory PracticeGood Laboratory Practice (GLP) comprises a set of principles that help to define and standardize the planning, performance monitoring, recording,

reporting and archiving processes within research institutions and commercial testing laboratories. The module covers standard operating procedures, quality assurance, receipt and handling of samples, monitoring performance of the study, reporting of study results and retention of records. Compliance to GLP regulations will also be covered.

Organic Chemistry In this module, students are introduced to the chemistry of hydrocarbons, alcohols, amines, aldehydes, ketones, carboxylic acids and their derivatives. The properties and chemical reactivity of these compounds in relation to the application of chemistry in life sciences will also be discussed.

Anatomy & PhysiologyThis module equips students with an understanding of the basic principles of homeostatic mechanisms and the anatomy and physiology of the cardiovascular, respiratory, renal, gastrointestinal, neuromuscular, endocrine and reproductive physiological systems that exist in the human body.

LEVEL 2.1 Applied Microbiology This is an advanced module in microbiology for second year students and is a continuation of the basic microbiology module. The module focuses on the importance of microorganisms as contaminating agents in the production of foods and pharmaceuticals. The module focuses on the techniques and methodologies involved in the analyses and prevention of microbiological contamination. The module also provides skills and knowledge in Good Manufacturing Practices, food hygiene auditing and in the preparation of a HACCP plan.

Biochemistry This module introduces fundamental and applied concepts in biochemistry. Topics covered include protein chemistry, enzymology, the metabolism of carbohydrates, lipids and proteins. Topics





covered during laboratory classes will include spectrophotometric assays, determination of kinetic parameters of enzymatic reactions, thin layer chromatography, dialysis, size exclusion chromatography and polyacrylamide electrophoresis.

Instrumentation & Analytical Chemistry In this module, students learn about the workings of various analytical instruments such as gas liquid chromatography, high-performance and low-pressure liquid chromatography, mass spectrometry and atomic absorption spectroscopy.


Aquaculture & Marine Biology The applied aspects of biotechnology in the aquaculture of fin and shell fish are introduced. Topics include fish spawning, larval and nursery management, assessment of growth, fish nutrition, diagnosis and treatment of common fish diseases, and aspects of water quality management and analysis. Marine life and ecosystems, marine environmental ecology and marine eco-tourism will also be covered.

Food Science & TechnologyThe module will cover key topics in modern food science, focusing on key issues which affect the import, production, testing and regulation of processed foods in Singapore. The course will introduce students to local and international food standards, and equip them to interpret data and information presented in the scientific

and non-scientific literature. Laboratory classes will focus on the analyses of processed foods.

Forensic ScienceThis module gives an overview of the techniques employed by crime scene investigators. It equips students with an understanding of forensic and DNA techniques used in criminal investigations and forensic DNA laboratories. Students will gain an understanding of the various aspects of forensic science and its applications. Through case studies, students will have a better understanding of crime scene reconstruction.

Biopharmaceutical ProcessingThe module covers quality systems in the pharmaceutical and biopharmaceutical industry. Downstream processing involving drying, cell separation technology, chromatography and crystallization will be covered in the module. Students will also be introduced to pharmaceutics.

LEVEL 2.2 Applied Biostatistics This module covers advanced statistical skills to analyse and interpret a wide range of biological, pre- clinical and clinical data, and preparation of data for scientific presentation. The statistical skills covered include biological experiment design, hypothesis testing, quantitative data analysis by parametric and non-parametric methods, qualitative data analysis by Chi-square and Fisher tests, and simple correlation and regression analysis for non-linear data. The scientific presentation section covers how to organise data, prepare and incorporate statistical results on graphs and interpretation of results.

ImmunologyThis module introduces the fundamentals of immunology and provides an understanding of how the immune system functions as an integrated defence system against diseases. Topics include an overview of the immune system, innate and adaptive immunity, humoral and cell-mediated immunity, immunization and

vaccination, and laboratory immunological techniques. Applications of immunology in overcoming assaults on the immune system and the principles of Hybridoma Technology are also covered.

Cell Culture & Bioprocess Engineering This module will equip students with strong aseptic techniques and application of cell culture in bioprocess engineering. Topics include biologics, cell lines, media, maintenance of cell cultures, and understanding of bioprocessing. Students will also acquire practical and theoretical knowledge of developing fermentation processes and manufacturing biological products. This module involves understanding basic bioseparation processes for purification of biological products. The module also includes applying bioprocess technology principles to scale-up production, economics, and regulatory considerations of bio-products derived from recombinant organisms, and animal cell culture.

Molecular BiologyThis module covers the fundamentals of molecular biology. Topics include DNA structure and replication, mRNA transcription, protein synthesis, regulation of gene expression in microorganisms, gene mutation and DNA repair mechanisms. In the area of recombinant DNA technology and molecular techniques, students will learn about the isolation of genomic and plasmid DNA, polymerase chain reaction, insertion of target DNA into cloning vector, transformation of E. coli competent cells, identification of recombinant clones, isolation of total RNA and gel electrophoresis. Students will be introduced to basic bioinformatics software for analysis of nucleic acid and protein sequences.

Advanced Organic ChemistryThis module covers basic organic reaction mechanisms like nucleophilic substitution (SN2 and SN1 mechanisms), elimination (E1 and E2 mechanisms), electrophilic addition and electrophilic aromatic substitution, nucleophilic substitution mechanisms (e.g. esterification), reactions of enols and enolates (e.g. alkylation, aldol, Claisen reaction). This module will also

YEAR 2 ELECTIVES



cover basic strategies in organic synthesis.

LEVEL 3.1 Genomics & Proteomics This module provides an insight into the fields of genomics and proteomics. Students will study the functions of genes and their interaction within a genome, the Human Genome Project, genetically modified organisms, gene therapy, protein expression with emphasis on the structure and functions of proteins, methods of purification and analyses of proteins and applications of proteomics.

BioinformaticsThis module equips students with essential bioinformatics computational skills. Topics include overview of biological informatics, microarray, protein structure prediction and structural databases, finding conserved motifs and patterns in proteins using online databases, and applications of software tools and resources in gene expression data analysis.

Biomanufacturing PracticesThe module focuses on practices applied in the manufacturing of biological agents such as vaccines, biologic drugs and antibodies. Topics include an overview of biomanufacturing process operations, process scale-up and reactor design and operation.

Forensic ChemistryThis module covers chemical analytical techniques used in forensic investigation and equips students with an understanding of methods and principles applied in the forensic chemistry and toxicology laboratories. Students will gain an understanding of the various aspects of forensic chemistry and its applications.

Food Processing & SafetyThe module will cover principles and techniques used in food industry which include mass and energy balance and their application in food unit operations, size

reduction, thermal processing, non-thermal processing and equipment. Under food safety, the proper handling, preparation and storage of food will be explored. Nature of contaminants, safety evaluation of food ingredients and food safety regulations (FDA, AVA) will also be covered.

Drug Discovery & Clinical TrialsThis module will introduce students to the drug discovery processes, the relationship between activity and functional group chemistry, chemistry of drugs and drug systems. The module also covers the role, composition and authority of Institutional Review Board (IRB), the phases of clinical trials, informed consent, ethical issues in clinical trials, and compliance to regulations.

Nutrition & Dietetic ScienceThis module provides students with a basic understanding of nutritional and dietetic concepts, including the role of micro and macronutrients in the diet and their effects on health. Principles of clinical nutrition and dietary requirements for special medical conditions and at different life stages will also be covered. Students will also learn to evaluate the evidence behind the use of common nutraceuticals and functional foods for health benefits as well as the regulations associated with the sales and marketing of such therapies.

LEVEL 3.2 Four-month Internship Students will undertake a four-month internship and project, giving them opportunities to relate and apply the knowledge acquired in classrooms to work situations and in research. They will be attached to research institutes and companies in various industries such as the pharmaceuticals, healthcare, food, agrotechnology and bioinformatics sectors. Students will also have the opportunity to go on overseas internships.

Capstone ProjectStudents will complete a final year research project under the guidance of an academic staff or industry

YEAR 3 ELECTIVES


mentor. The Capstone Project can cover any of the key areas in life science research including Molecular Biosciences, Industrial Biotechnology, Food Technology, Aquatic Science & Technology, Environmental Technology and Urban Horticulture & Greenscape. Students will be able to integrate and apply the knowledge and skills learned from the course. They will be involved in report writing as well as presenting the outcomes of the project in poster and oral presentations. The Capstone Project will further strengthen their writing and communication skills as well as analytical and problem solving skills, thus preparing them for the industry or further studies.


This course provides students with a unique opportunity to undergo broad-based training in disciplines ranging from medicinal chemistry, pharmacology, clinical biochemistry and pharmaceutics, to pharmacy practice and pharmacotherapeutics. Electives in Biopharmaceutical Analysis, Complementary Medicine & Traditional Chinese Medicine, Nutrition & Dietetic Science and Translational Medicine cater to students’ varied interests and provide insights into these specialised areas.

Students undertake their final year Integrated Pharmacy Training Programme (IPTP) at the National University Hospital (NUH), where they are taught by pharmacists. Their final year project allows them to develop skills in clinical pharmacy research.

ENTRY REQUIREMENTS




Candidates with colour vision deficiency should not apply for the course.


English Language*



Biology component)

or Biotechnology


1-7

1-6

1-6

CAREER PROSPECTS The numerous government initiatives encouraging thegrowth of the pharmaceutical and biomedical industries, as well as the increasing need for healthcare services in Singapore, ensure good employment opportunities for our graduates.

PHARM graduates have a broad-based education in the chemical, biomedical and pharmaceutical sciences. In addition, they acquire relevant and specialised practical skills in the healthcare setting at NUH. PHARM graduates are well-equipped to work in a wide variety of jobs such as pharmaceutical and biomedical manufacturing, research and clinical trials, sales and marketing, and pharmacy practice in retail and hospital pharmacies.


The strong foundation that PHARM students have in pharmacy practice and pharmaceutical sciences gives them a head-start when applying for courses in the pharmaceutical, pharmacy, biomedical sciences and other healthcare-related courses in universities around the world. In addition, PHARM graduates can also apply to undertake degrees in a wide range of disciplines, including bioengineering, education, arts, architecture, dentistry, business, psychology and social sciences.

Well-known overseas universities such as the following will grant one to two years’ exemption for three and four year degree courses:

• Monash University (Australia)

• RMIT University (Australia)

• University of Melbourne (Australia)

• University of Queensland (Australia)

• University of Sydney (Australia)

• University of Auckland (New Zealand))

• University of Otago (New Zealand)

• University of Dundee (UK)

In an exclusive partnership with the Department of Pharmacy of the National University Hospital (NUH), the Diploma in Pharmacy Science (PHARM) enables students to receive training and guidance from practising pharmacists, and exposure to pharmaceutical practices in a clinical environment. The partnership allows students to learn in a teaching hospital with comprehensive services and state-of-the-art facilities.

PHARMPHARMACY DIPLOMA IN

SCIENCE

DIPLOMA IN PHARMACY SCIENCE (PHARM)


• University of London (UK)

You can also deepen your skills and further your careerby enrolling in the following post-diploma coursesoffered by Ngee Ann Polytechnic:

• Advanced Diploma in Medical and Pharmaceutical Technology• Specialist Diploma in Analytical Sciences*• Specialist Diploma in Veterinary Clinical Practice*


COURSE MODULES

LEVEL 1.1Anatomy & PhysiologyThis module introduces the anatomy and functions of the human body. It equips students with an understanding of the anatomy and physiology of the cardiovascular, respiratory, renal, gastrointestinal, neuromuscular, skeletal, endocrine and reproductive systems.

Cell & Molecular Biology This module explores mammalian cells, tissue and organ systems, and prokaryotic and eukaryotic genetics at the molecular level. Topics include the fundamental chemicals of life, structure and the function of cells and organelles, cell division, cytogenetics, DNA structure, replication, transcription, and translation, protein synthesis, gene mutation, cell communication, mitosis and meiosis, genetics and hereditary, apoptosis and cancer.

COURSE CURRICULUM



YEAR 1Level 1.1 (27.5 hours per week) Cell & Molecular Biology 7Anatomy & Physiology 6Organic & Biological Chemistry 7Innovation Toolkit ^ 4Sports & Wellness ^ 2Career & Professional Preparation I 1.5

Level 1.2 (24 hours per week) Introduction to Pharmacy 7Biostatistics 3Inorganic & Physical Chemistry 7Mathematics 3Critical Thinking & Communication ^ 4

YEAR 3Level 3.1 (32 hours per week) Clinical Pharmacy 8Good Dispensing Skills 4Pharmacotherapeutics 9Project A 7World Issues: A Singapore Perspective ^ 2Interdisciplinary Studies (IS) elective ^ 2 Level 3.2 (32 hours per week) Aseptic Dispensing & Compounding 5Pharmacy Management & Logistics 8Pharmacy Practice 8Project B 7 Electives Biopharmaceutical Analysis 4Complementary Medicine & Traditional Chinese Medicine (TCM) 4Translational Medicine 4Nutrition & Dietetic Science 4

YEAR 2Level 2.1 (25 hours per week) Current Good Manufacturing Practice 2Pharmaceutical Analysis 6Pharmaceutics 6Pharmacology 5Pathology 4Interdisciplinary Studies (IS) elective ^ 2

Level 2.2 (26 hours per week) Applied Biostatistics 3Clinical Biochemistry 4Clinical Immunology 4Medicinal Chemistry & Drug Discovery 5Microbiology & Infectious Diseases 6Career & Professional Preparation II 2 Interdisciplinary Studies (IS) elective ^ 2





Organic & Biological Chemistry In this module, students are introduced to the chemistry of hydrocarbons, alcohols, amines, aldehydes, ketones, carboxylic acids and their derivatives. The structures, functions and chemical reactions of biological molecules, including carbohydrates, lipids and proteins and their derivatives are also covered.

Career & Professional Preparation IThis module is part of the Education and Career Guidance framework to provide students with the tools and resources necessary for their career and/ or further education. In this first module, students willundergo personal discovery and exploration of industry and career prospects. Students will learn how to and set achievable goals in preparation for their future. Students will also learn the importance of passion and professionalism, and basic teamwork and interpersonal skills.

LEVEL 1.2 Introduction to PharmacyThis module introduces students to pharmaceuticalsand the roles, responsibilities, job scope and future ofpharmacists and pharmacy technicians. It providesa foundation for subsequent modules in the course.Introductory topics in pharmacology, pharmaceuticalscience and pharmaceutics will be covered, and students will learn to perform pharmaceuticalcalculations to determine dosages.

Biostatistics This module is designed to provide students with basic statistical skills to analyse and interpret simple biological, pre-clinical and clinical data. The basic statistical skills covered are descriptive statistics, data distribution, set sample size, measurement of central tendency, scatter diagram, cluster analysis and simple linear correlation and regression analysis for linear data. The presentation of data in graphical forms using Microsoft Excel covers selection and preparation of different types of graphs, how to write titles and legends and interpretation of results.

Inorganic & Physical Chemistry The module covers the structure of matter, chemical bonding, thermochemistry, chemical equilibria, kinetics, electrochemistry and redox reactions, transition metal chemistry, and chemistry of solutions, including acids, bases and buffers, polarity and solubility.

Mathematics This module provides students with a fundamental analytical knowledge of mathematics essential for the study of pharmaceutical and life science. The rules of conversion of one unit of measurement to another as well as basic mathematical operations will be covered. Students will also learn the properties governing the operation of polynomial, exponential and logarithmic functions and understand their applications in chemistry and biology.

LEVEL 2.1 Current Good Manufacturing Practice This module aims to equip students with an understanding of current Good Manufacturing Practice regulations for pharmaceuticals and related products. Various aspects, such as attributes of materials, labelling, materials in process, finished pharmaceuticals, manufacturing validation, quality control, personnel and facilities are covered.

Pharmaceutical Analysis This module studies modern analytical techniques that are used for the detection, identification and quantitative determination of drugs and related substances. Techniques for the evaluation of analytical data and validation of analytical methods will be discussed.

Pharmaceutics This module focuses on the design and formulation of two-phase pharmaceutical products, including suspensions, emulsions and solid pharmaceutical products, and how they relate to absorption and drug delivery routes. Topics include drug formulations, preparation and dispensing of pharmaceuticals, introduction to biopharmaceutics, pharmacokinetics,

bioavailability, specialised dosage forms, prodrugs, liposomes, targeted drug delivery, drug stability of various formulations and shelf life.

Pharmacology This module covers the basic principles of pharmacology, the mechanism of drug action, dose response relation, adverse reaction, pharmacokinetics (absorption, distribution, metabolism, elimination) and major drug classes.

Pathology This module helps students to understand the causes and mechanisms of disease. Students will learn about disease processes affecting common organ systems. The mechanisms of disease, natural history and progression and implications for treatment and prevention will be discussed.

LEVEL 2.2 Applied Biostatistics This module covers advanced statistical skills to analyse and interpret a wide range of biological, pre-clinical and clinical data, and preparation of data for scientific presentation. The statistical skills covered are biological experiment design, hypothesis testing, quantitative data analysis by parametric and non-parametric methods, qualitative data analysis by Chi-square and Fisher tests, and simple correlation and regression analysis for non-linear data. The scientific presentation section covers how to organise data, prepare and incorporate statistical results on graphs and interpretation of results.

Clinical Biochemistry This module expands on the basic biochemical concepts taught in earlier modules and allows students to better understand the biochemical processes in the human body systems. The application of core biochemistry knowledge to the diagnosis and treatment of diseases in clinical practice is covered.

Clinical Immunology This module introduces students to the fundamentals of



immunology. The module will provide an understanding of how the immune system functions. Topics include an overview of the immune system, innate and adaptive immunity, humoral and cell-mediated immunity, immunisation, vaccination, laboratory immunological techniques, diseases of the immune system and antibody-based therapies.

Medicinal Chemistry & Drug Discovery The first part of this module highlights the drug discovery process and how compounds are identified and developed into drugs. The second part of the module introduces students to the chemistry of drugs and drug systems, with particular emphasis on heterocyclic chemistry and the major drug classes. They will also learn about the relationship between activity and functional group chemistry, and drug design.

Microbiology & Infectious Diseases This module studies medical microbiology, microbial pathogenesis and antimicrobial therapy. The module covers fundamental information regarding microorganisms, specifically pathogenic bacteria, fungi and viruses. Topics include mechanism of disease production, antibiotic resistance, emerging pathogens, contamination, sterilisation and disinfection, infection control, methods of treatment and prevention of disease.


LEVEL 3.1 Clinical Pharmacy This module introduces the rational selection and the use and effects of drugs on individual patients and

patient groups. Students will learn the application of quantitative clinical data in the optimisation of drug therapy, as well as pertinent clinical therapeutic material that enables them to optimise patient therapies in a wide range of disorders.

Good Dispensing Skills This module equips students with a better understanding of good dispensing practice and patient counselling skills. Students will develop good communication skills and techniques required to respond effectively to the needs of patients in a pharmacy. They will learn about guidelines for prescription handling and practise dispensing common prescriptions.

Pharmacotherapeutics This module highlights the use of drugs in the treatment of diseases as well as the biochemical and physiologic effects of drugs and their mechanisms of action. Students will learn how drugs are evaluated, the mechanism of how drugs act, and their side effects.

Project AIn Project A, students will undertake a clinical, operational or laboratory research project relevant to pharmacy practice in groups of two or three under the supervision of NUH staff. Students will commence Project A by attending a series of lectures covering aspects such as writing a literature review, project management and statistical analysis of data.

LEVEL 3.2 Aseptic Dispensing & Compounding This module provides students with the basic skills used in the pharmacy compounding laboratory. This includes an understanding of the techniques, calculations, facilities and quality control and assurance in aseptic dispensing. Students will learn to prepare total parenteral and enteral nutrition, IV admixtures and cytotoxic drug preparation, and will be given hands-on experience in compounding different types of extemporaneous preparations.

Pharmacy Management & Logistics This module focuses on business aspects of the operation of hospital and retail pharmacies. Topics include procurement, logistics and inventory management, business automation, marketing and principles of finance pertaining to the operations of a pharmacy.

Pharmacy Practice This module equips students with effective communication skills for interacting with patients, caregivers and other health professionals. Topics include how to respond to patients, crisis intervention, dealing with people from culturally diverse backgrounds, dealing with grief and loss, and patient education. Good pharmacy practice relating to the dispensing and reformulation of commercial pharmaceutical products will also be discussed, as well as the Code of Ethics, and the impact of legal and ethical issues on drug management.

Project BIn Project B, students will continue to work on their research project. Upon completion of their project, students will submit a written scientific report and present their findings by giving an oral PowerPoint presentation and a scientific poster presentation.

Biopharmaceutical AnalysisThis module is designed to equip students with knowledge and molecular techniques that are used to analyse raw materials and biological products. Topics include an overview on biologics production using microbial and mammalian systems, detection of adventitious agents in biological products using quantitative PCR (qPCR), endotoxin and pyrogen testing, bioburden test, and detection of residual host cell proteins using enzyme linked immunosorbent assay (HCP-ELISA). An overview on pharmaceutical law and regulatory landscape will also be covered.

ELECTIVES



Complementary Medicine & Traditional Chinese Medicine (TCM)This module describes how philosophies of alternative medicines and therapies are used to complement those of conventional medicine. The mechanism of action, dosage forms and pharmacological aspectsof selected complementary medicines and traditional Chinese medicines will be covered, including the responsibilities associated with the sale and marketing of complementary medicines.

Translational MedicineThis module emphasises the molecular and cellular basis of disease processes and helps students understand the importance of molecular targets for disease prevention and therapy. Students will gain new understanding of disease, clinical and molecular diagnostic tools.

Nutrition & Dietetic ScienceThis module provides students with a basic understanding of nutritional and dietetic concepts, including the role of micro and macronutrients in the diet and their effects on health. Principles of clinical nutrition and dietary requirements for special medical conditions and at different life stages will also be covered. Students will also learn to evaluate the evidence behind the use of common nutraceuticals and functional foods for health benefits as well as the regulations associated with the sales and marketing of such therapies.



Students will be trained to properly care for, handle and manage various animals, ranging from laboratory and farm animals to pets. In the biomedical science sector, animal models enable researchers to study human diseases more effectively and are critical for the development of new medicines and therapeutics. Students will also be trained to assist veterinarians in a clinic setting. With the growth of pet ownership, there is an increasing need for skilled persons in the area of animal medical care.

Students will learn about the maintenance and well-being of animals through modules such as Animal Anatomy & Physiology, Animal Nutrition, Animal Welfare, Behaviour & Handling and Animal Husbandry & Breeding. Modules such as Wildlife Conservation & Biodiversity will give students an understanding of animals in their natural habitats. This course will also cover the clinical diagnosis and treatment of animal diseases through modules such as Animal Diseases & Pathology and Clinical Diagnostics, Surgical & Veterinary Practices. Furthermore, the mechanisms of disease will be covered in Veterinary Immunology and Veterinary Pharmacology & Toxicology.

Underlying these skills and knowledge are the essential elements of a life science programme (including Cell Biology, Cell Culture & Tissue Applications, Molecular Biology & Bioinformatics). The course thus provides an excellent pathway for students to enter a career in biomedical research.

In their final year of study, students will undertake a four-month local or overseas internship. Students will be attached to veterinary clinics, animal theme parks (such as the Singapore Zoo, Jurong Bird Park, River Safari and Marine Life Park) or research laboratories. Students will also carry out a final year research project and complete advanced modules such as Animal Genomics & Proteomics, Animal Husbandry & Breeding, and Preclinical & Clinical Trials.

ENTRY REQUIREMENTS




CAREER PROSPECTS

VBS graduates enjoy a wide range of careers in the veterinary and biomedical science industries. They can work as research assistants in research institutions and university laboratories, or work as veterinary bioscientists in animal research facilities and pre-clinical trial centres.

VBS graduates can be employed as veterinary assistants in veterinary clinics and animal hospitals. They can also find employment in animal theme parks (such as the Singapore Zoo, Jurong Bird Park, Night Safari, River Safari and Marine Life Park) and equine establishments (such as the Bukit Timah Saddle Club and Singapore Polo Club). Other employers include animal-related businesses (such as pet shops, pet hotels and pet supply companies) as well as government agencies (such as the Agri-food and Veterinary Authority).


English Language*



Biology component)

or Biotechnology


1-7

1-6

1-6

The Diploma in Veterinary Bioscience (VBS) is a unique course that combines the strengths of both veterinary and biomedical sciences. The course prepares students for a wide range of careers.

VBSVETERINARYDIPLOMA IN

BIOSCIENCE



VBS graduates can be accepted into biological science and biomedical science degrees offered by both local and overseas universities if they wish to pursue careers in the life sciences. Other related areas include degrees in Zoology and Animal Sciences from overseas universities.

VBS graduates can also become veterinarians by enrolling into Veterinary Medicine programmes offered by universities in Australia, New Zealand, and the UK. Murdoch University (Australia) offers our graduates a one-year exemption from their Bachelor of Science in Veterinary Biology & Doctor of Veterinary Medicine programme. The University of Sydney (Australia) also offers a one-year exemption from their Bachelor of Veterinary Biology & Doctor of Veterinary Medicine programme. Ross University School of Veterinary Medicine (St Kitts) offers VBS graduates direct entry into their accelerated Doctor of Veterinary Medicine programme.

You can also deepen your skills and further your career by enrolling in the following post-diploma courses offered by Ngee Ann Polytechnic:

• Advanced Diploma in Medical and Pharmaceutical Technology• Specialist Diploma in Analytical Sciences*• Specialist Diploma in Veterinary Clinical Practice*


COURSE CURRICULUM


YEAR 1Level 1.1 (28.5 hours per week) Animal Anatomy & Physiology 6Animal Nutrition 3.5Inorganic & Physical Chemistry 7Veterinary Microbiology 6Innovation Toolkit ^ 4Sports & Wellness ^ 2

Level 1.2 (28.5 hours per week) Animal Welfare, Behaviour & Handling 4Biostatistics 3Cell Biology 7Organic & Biological Chemistry 7Wildlife Conservation & Biodiversity 2Career & Professional Preparation I 1.5Critical Thinking & Communication ^ 4

YEAR 3Level 3.1 (24.5 hours per week) Animal Genomics & Proteomics 6Animal Husbandry & Breeding 4Preclinical & Clinical Trials 2.5Project A 8World Issues: A Singapore Perspective ^ 2Interdisciplinary Studies (IS) elective ^ 2 Level 3.2 (24 hours per week) Project B 8Four-month Internship 16


YEAR 2Level 2.1 (27 hours per week) Applied Biostatistics 3Aquaculture & Fish Diseases 5Cell Culture & Tissue Applications 5Veterinary Immunology 6Veterinary Pharmacology & Toxicology 4Career & Professional Preparation II 2Interdisciplinary Studies (IS) elective ^ 2

Level 2.2 (25.5 hours per week) Animal Developmental Biology & Genetics 2.5Animal Diseases & Pathology 6Clinical Biochemistry & Haematology 4.5Clinical Diagnostics, Surgical & Veterinary Practices 4.5 Molecular Biology & Bioinformatics 6Interdisciplinary Studies (IS) elective ^ 2



DIPLOMA IN VETERINARY BIOSCIENCE (VBS)


COURSE MODULES

LEVEL 1.1Animal Anatomy & Physiology This module introduces the anatomy and functions of the animal body. This module equips students with an understanding of the anatomy and physiology of the integumentary, musculoskeletal, respiratory, cardiovascular, gastrointestinal, urinary, reproductive, nervous and endocrine systems.

Animal Nutrition This module provides students with an opportunity to understand animal nutrition and its importance in growth and well-being of laboratory, domesticated and farm animals. Students will have an insight into the nutritional requirements of large and small animals and the use of animal feed additives and growth promoters. The digestive processes and functions of the gastrointestinal tract will be studied. This module will provide some knowledge on the feed milling processes, management of a feedmill, evaluation methods of the nutrients for feed rations and formulation of animal feed.Students will understand the use of raw ingredients in the formulation of commercial feed and the regulatory procedures involved to ensure safe production of animal feedstuffs. Students will also acquire knowledge regarding the different types of pet foods and regulation of pet foods in Singapore. Alternative sources of animal feed such as the use of unconventional animal feeds and feed replacement will be studied.

Inorganic & Physical Chemistry This module introduces students to aspects of inorganic and physical chemistry. Topics covered comprise the structure of matter, chemical bonding, thermochemistry, chemical equilibria, kinetics, electrochemistry, redox reactions, transition metal chemistry, and chemistry of solutions including acids, bases and buffers.

Veterinary Microbiology This module provides students with an understanding of how bacteria of veterinary importance cause disease

in animals. Pathogenic bacteria studied will include those that cause gastrointestinal diseases, respiratory diseases, reproductive diseases, skin and nervous system diseases. This module also includes the study of molecular mechanisms underlying host/pathogen interactions in the pathogenesis of animal diseases, as well as aspects of disease control, including diagnosis, antibiotic treatment and vaccination. Standard microbial laboratory techniques involving the isolation, culture and identification bacteria (based on microbial metabolic characterisation and microscopy examination) will also be covered.

LEVEL 1.2 Animal Welfare, Behaviour & Handling This module provides students with an understanding of the proper handling and restraint of domestic animals, as well as the responsible care and use of laboratory animals for research purposes. The techniques include step-by-step instructions for performing each procedure and the purposes, followed by learning the potential complications. This module also covers the fundamental principles underlying animal behaviour, such as animal learning behaviour, sexual selection and mating behaviours, kinship, cooperation, foraging, communication, aggression and elimination behaviours. The basic principles of animal welfare will also be explained, including methods of measuring animal welfare (such as the ‘Five Freedoms’ and preference testing) and the limitations of such assessment methods.

Biostatistics This module is designed to provide students with basic statistical skills to analyse and interpret simple biological, pre-clinical and clinical data. Students will acquire proficiency in the quantitative analysis of scientific data. The statistical skills covered include descriptive statistics, data distribution, set sample size, measurement of central tendency, scatter diagram, cluster analysis and simple linear correlation and regression analysis for linear data. The presentation of data in graphical forms using Microsoft Excel covers

selection and preparation of different types of graphs, how to write titles and legends and interpretation of results. Students will have proficiency in the use statistical software for data analysis, preparation of documents and presentation of results.

Cell Biology This module explores mammalian cells, tissue and organ systems, and prokaryotic and eukaryotic genetics at the molecular level. Topics include the fundamental chemicals of life, structure and the function of cells and organelles, DNA structure, replication, transcription and translation, protein synthesis, gene mutation, cell communication, cell division (mitosis and meiosis), genetics and hereditary, apoptosis and cancer.

Organic & Biological Chemistry This module gives students a strong foundation in basic organic chemistry. Topics include the IUPAC nomenclature, structural formulae, preparations and reactions of the main classes of organic compounds namely alkanes, alkenes, alkynes, benzene, alcohols, thiols, ether, aldehydes, ketones, amines, carboxylic acids and derivatives.

Wildlife Conservation & Biodiversity This module covers aspects of biodiversity conservation, and discusses how biodiversity is generated and maintained. This module will also address issues such as how we can manage and restore habitats, the formulation of strategies for the conservation of species threatened with extinction, and human-wildlife conflict situations. National policies and legislation pertaining to conservation of local biodiversity will also be covered.

Career & Professional Preparation I This module is part of the Education and Career Guidance framework to provide students with the tools and resources necessary for their career and/or further education. In this first module, students will undergo personal discovery and exploration of industry and career prospects. Students will learn how to plan and set achievable goals in preparation for their future. Students will also learn the importance of passion and



professionalism, and basic teamwork and interpersonal skills.

LEVEL 2.1 Applied Biostatistics This module covers advanced statistical skills to analyse and interpret a wide range of biological, pre-clinical and clinical data, and preparation of data for scientific presentation. The statistical skills covered include biological experiment design, hypothesis testing, quantitative data analysis by parametric and non-parametric methods, qualitative data analysis by Chi-square and Fisher tests, and simple correlation and regression analysis for non-linear data. The scientific presentation section covers how to organise data, prepare and incorporate statistical results on graphs and interpretation of results.

Aquaculture & Fish Diseases This module equips students with the knowledge of the anatomy, physiology, nutritional requirements and reproductive systems in mainly Teleost fish as well as provides an introduction to aquaculture and the various aquaculture systems employed today. Students will also be introduced to a variety of common and significant fish diseases, the principles of disease diagnosis, treatment and health management of various fisheries and aquariums.

Cell Culture & Tissue Applications This module is a detailed study of the techniques used in the culturing of cells and tissues. Topics include the preparation of media, cell viability checks, passaging of inherent cells, cryopreservation, cloning and mycoplasma assays. Applications of animal cell culture, tissue engineering and rapid prototyping are also covered.

Veterinary Immunology This module introduces students to the fundamentals of immunology and provides an understanding of how the immune system functions as an integrated defence system against disease. Topics include an overview

of the immune system of vertebrates, innate and adaptive immunity, humoral and cell-mediated immunity, immunisation, vaccination, laboratory immunological techniques, diseases of the immune system and antibody-based therapies.

Veterinary Pharmacology & Toxicology This module covers the basic principles of veterinary pharmacology, pharmacodynamics, pharmacokinetics (absorption, distribution, metabolism, elimination), the major drug classes, basic anaesthesiology, and an introduction to toxicology. Clinical and research applications of the drugs will be discussed in relation to the drug effects and mechanisms of action. Students will have the opportunity to practise animal handling skills and techniques for administration of medication, as well as perform drug calculations.

Career & Professional Preparation IIThis module is part of the Education and Career Guidance framework to provide students with the tools and resources necessary for their further career and/or education. In this module, students will explore basic job search strategies, practice writing effective resumes and cover letters, and learn interview skills. Students will also learn professional and intercultural communication skills to prepare them for a dynamic and diverse workplace. LEVEL 2.2 Animal Developmental Biology & Genetics This module discusses developmental biology, genetics approaches to understanding animal embryonic development, and genes that are involved in body plan formation and morphogenesis. Other topics include the pattern of inheritance, mutation, and roles of genes and environmental factors in relation to animal health are also covered.

Animal Diseases & Pathology This module trains students in the skills necessary for the investigation, prevention and control of common infectious and non-infectious animal diseases.

The study of pathogenic mechanisms and the morphological aspects of disease will also be covered. Emphasis will be given to common diseases affecting small laboratory animals. Common diseases affecting laboratory animals will also be briefly discussed.

Clinical Biochemistry & Haematology This module focuses on disease diagnosis and monitoring in clinical biochemistry and haematology as reflected in veterinary clinic practice. The clinical biochemistry component will cover enzyme kinetics and metabolism, and give students an understanding of metabolic diseases. The haematology component will cover aspects of blood analysis and will provide practical training in performing blood smears, carrying out blood biochemistry and completing blood count profiles, which are routinely conducted in veterinary clinics.

Clinical Diagnostics, Surgical & Veterinary Practices This module covers introductory clinical diagnostics and basic surgical techniques. Students will be taught how to handle clinical samples, prepare and examine skin scrapings, urine, fecal bacteriological and cytological samples. Students will also learn to perform histological sections and stain tissues for diagnostic purposes. Students will be introduced to the perioperative preparation of an animal for surgery, monitoring of an animal during surgery, and surgical instrumentation. Management of a veterinary practice will also be briefly covered.

Molecular Biology & Bioinformatics This module covers the fundamentals of molecular biology coupled with techniques in bioinformatics in order to provide students with analytical skills that are useful in analysis of molecular data. The molecular biology component covers topics such as DNA structure and replication, gene expression, gene mutation, DNA repair mechanisms and recombinant DNA technology. Students will learn how biological data such as nucleic acid and protein sequences are archived and how to retrieve such information from



public databases. Students will be introduced to current bioinformatics software that can be used for analysis of nucleic acid and protein sequences, and for designing of PCR primers.

LEVEL 3.1 Animal Genomics & Proteomics This module provides current information on a range of topics, including animal genome projects, transgenic animals and cloning, and ethical issues involved in the genetic engineering of animals. Application of genomics & proteomics to the study of animal disease, reproduction & breeding will also be discussed. The practical component will cover gene and protein expression, with an emphasis on protein identification and separation strategies.

Animal Husbandry & Breeding This module introduces students to the field of good animal husbandry management and breeding. Students will learn how to take proper care of farm and pet animals. Students will acquire knowledge and skills on animal husbandry and understand the role of animals and the impact of animal health in the economy. This module covers the essentials of farming practice, particularly the breeding and raising of livestock. The impact of genetics on breeding and the selection of desirable heritable traits will be discussed. Techniques which are used to improve herd genetics, such as artificial insemination and embryo transfer, will also be discussed.

Preclinical & Clinical Trials The module introduces students to the various stages in biomedical research, ranging from preclinical to clinical trials. Students will be introduced to various important government authorities that are involved in the approval and establishment of both scientific and ethical guidelines pertaining to biomedical research.

Project AIn Project A, students will work on a research project in groups of two or three in an area that is of interest

to them, under the supervision of a staff member. Students will commence Project A by attending a series of lectures covering aspects such as writing a literature review, basic laboratory safety, project management and statistical analysis of data, which is then followed by practical work in the laboratory.

LEVEL 3.2 Project BIn Project B, students will continue to work on their research project in the laboratory. Upon completion of their project, students will submit a written scientific report and present their findings by giving an oral PowerPoint presentation and a scientific poster presentation.

Four-month Internship Students will undertake a four-month internship, which will give them opportunities to relate and apply the knowledge acquired in classrooms to work situations and in research. Students will be attached to local research institutes and companies in various industries (such as veterinary clinics and hospitals, animal theme parks, animal breeding facilities, biomedical science research laboratories, and veterinary regulatory bodies). Students will also have the opportunity to go on overseas internships.


Date post:	12-Aug-2020
Category:	Documents
Upload:	others
View:	14 times
Download:	1 times

K01 SCHOOL OF LIFE SCIENCES & CHEMICAL K02 · K01 SCHOOL OF LIFE SCIENCES & CHEMICAL K02 The...

Documents