Netmedi Oy / @kaikuhealth / @laurisippola

Confidential / Netmedi Oy

2013First clinical research project with HUCH

1in the Nordics

10kpatients

Agenda

1. Kaiku Health2. Patient reported outcomes3. Future of data driven care

K L I N I K A A RA U

K L I N I K Z Ü R I C HK L I N I K M Ä N N E D O R F

K L I N I K L A U S A N N E

S O M E O F O U R R E F E R E N C E S

Kaiku is a web-platform that automates symptom follow-up and data capture during and after cancer treatment.

The patient stays connected – anywhere, anytime, any device.

Patient reports structured feedback on adverse events and quality of life.

Kaiku can give information to the patient.

Kaiku alerts automatically the medical staff according to the pre-programed parameters.

95% 75% x10Positive impact on

treatment experience by patients

Reduction in calls Real-world data

Data from 2015

2013

-Q1

2013

-Q2

2013

-Q3

2013

-Q4

2014

-Q1

2014

-Q2

2014

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2014

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2015

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2015

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2015

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2015

-Q4

0

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20000

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120000

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180000Patients Data points

Num

ber o

f pati

ents

3460 patients11% average

monthly growth

167 110 data points

356 % growth during in 12

months

Num

ber o

f dat

a po

ints

15 25+ 89%Centers Adverse event follow-

up templates for different cancer and

therapy combinations

Patient compliance (registered /

invited)

Agenda

1. Kaiku Health2. Patient reported outcomes3. Future of data driven care

Why is data about patient’s experience significant for better healthcare?Patient-reported outcomes (PRO)= PRO is any report of the status of a patient's health condition that comes directly from the patient, without interpretation of the patient's response by a clinician or anyone else. (US-FDA)

Confidential / Netmedi Oy

Why are PROs important?

"After all, only the patient himself is aware of his wellbeing and can report on possible warning signs, while the doctor can use these reports to evaluate the progress of the disease and treatments on the basis of their medical expertise."

Basch et al: Symptom Monitoring With Patient-Reported Outcomes During Routine Cancer Treatment: A Randomized

Controlled Trial. Clin Oncol 34:557-565, 2016

Web-based symptom reporting with automated clinician e-mail alerts resulted in better quality of life, fewer emergency room visits and longer duration of treatment as well as better quality-adjusted survival for patients. (N = 766)

Agenda

1. Kaiku Health2. Patient reported outcomes3. Future of data driven care

Patient is connected with Kaiku® Health.

Kaiku® Health captures specific symptom and quality of life data.

Kaiku® Health automatically gives routine instructions to frequently asked questions.

Kaiku® Health

algorithms m

ine the

data.

Kaiku® Health filters the patients.

Kaiku® Health notifies the medical staff according to pre-definedparameters.

Kaiku® creates analytics:• Individual patient• Populations• Clinical trial support

Case 1: Monitoring outcomes of immunotherapy and complex combinations

Prevent

Anticipate

Detect

Treat

Monitor

Source: Annals of Oncology: 559-574, 2016

Case 2: Forecasting risk

25%Risk of recurrence

Improve quality of

lifeMonitor Forecast

Future:

Confidential / Netmedi Oy

Enabling data-driven care and personalized care.Kaiku is the patient’s individual guide through cancer treatment and recovery, and a real-time dashboard that allows the caregiver to improve outcome-driven care.

Confidential / Netmedi Oy

Thank you.

Lauri SippolaCEO and Co-founder+358 40 744 7481

lauri.sippola@netmedi.fi @laurisippola

www.kaikuhealth.com