BY: SEPTI D.R.

LEUKEMIA Definition Etiology Classification:

Leukemia Mieloid CML – Chronic Mieloid Leukemia AML – Acut Mieloid Leukemia

Leukemia Limfoid CLL – Chronic Limfoblastik Leukemia ALL – Acut Limfoblastik Leukemia

Review..Review..COMPONENTS OF BLOODCOMPONENTS OF BLOOD

BODY FLUID

INTRACELLULAR70 %

EXTRACELLULAR30 %

INTERSTITIAL24 %

INTRAVASKULER6 %

WBC (White Blood Cell) WBC (White Blood Cell) FormationFormation

In the adult, all blood cell formation occurs in the red bone marrow

All blood cells develop from stem cells called hemocytoblasts

Hemocytoblast

Myeloid Stem Cell

Lymphoid Stem Cell

Red Blood Cells

Monocytes

Platelets

Granulocytes

Lymphocytes

Types of WBCsTypes of WBCs1. Granulocytes

Visible granules. Tdd: Basophil Eosinophil Neutrophil

2. Agranulocytes Tdk ada visible

granules. Tdd : Lymphocyte Monocyte

Leukemia Clinical manifestation Pathophysiology Complication: Sepsis, BM failure Diagnostic test: blood test, BM Aspiration and biopsy, Immunochemistry,

cytochemistry, cytogenetic, spinal tap, X-ray

Treatment:Blood transfusion, chemotherapy, psychosocial approach

Chemotherapy Chemotherapy agent:

Alkylating agent, antimetabolites, antibiotics, hormones and corticosteroids, enzymes

Chemotherapeutic phases:

Remission induction, intensification/consolidation therapy, CNS prophylactic therapy, maintenance

Nursing care

Assessment : signs & symptom Nursing diagnosis Planning Implementation Evaluation

Nursing diagnosis

Risk of infection Imbalanced Nutrition: Less than

body requirements Intolerant activity Pain

Nursing Care Plans