L A B O R A T O R I E S O F A M E R I C AL A B O R A T O R I E S O F A M E R I C A

Emerging Technology Opportunities in Health Emerging Technology Opportunities in Health and Wellness- and Wellness- From Potential to ProductFrom Potential to Product

Deepak Ayyagari, PhD

Principal Scientist, Sharp Labs of America

Secretary, Continua Health Alliance

September 25, 2007

L A B O R A T O R I E S O F A M E R I C AL A B O R A T O R I E S O F A M E R I C A

A history of "firsts"

1912 1915

Tokuji Hayakawa invents the Ever-Sharp Pencil.

1925

Assembly and marketing of crystal radio sets.

1953

Mass production of TV sets to coincide with Japan's first TV broadcasts.

1960

Mass production of color TV sets. Color TV broadcasting begins in Japan.

Sharp's founder, Tokuji Hayakawa, establishes a metal works in Tokyo.

Sharp History -1

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1962 1963

1964

Development and mass production of the world's first all-transistor desktop calculator.

Mass production of solar cells and silicon-based photovoltaic cells.

Mass production of microwave ovens.

1969

Development of ELSI chips. Marketing of electronic calculators incorporating ELSIs.

1970

Akira Saeki becomes president.

Changes name from Hayakawa ElectricIndustry Co. to Sharp Corporation.

Sharp History- 2

L A B O R A T O R I E S O F A M E R I C AL A B O R A T O R I E S O F A M E R I C A

1973

Development of the world's first COS electronic calculator incorporating an LCD.

1979

Development and introduction of the world's first super-thin 1.6-mm card-sized calculator.

1981

Development of the world's first long-life laser diode.

1982

Introduction of the world's first combination PC/TV set.

Sharp History- 3

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1986 1987 1988

1989 1990

Development of an electronic organizer with multiple functions.

Development of the world's first 14-inch large-screen, thin-profile, high-definition color TFT LCD unit.

Introduction of 100-inch LCD projectors that can be carried from room to room.

Introduction of a home copier/ facsimile.

Haruo Tsuji becomes president.

Sharp History -4

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1992

Development and introduction of an HDTV with simplified MUSE decoder.

1993Development and introduction of an all-in-one Personal Information Tool for business use.

1996

Development and introduction of the world's first LCD Viewcam. Introduction of a

fully automatic washing machine with hole-less tub that saves water and detergent by 30%.

Introduction of an Internet-ready color LCD notebook PC, equipped with a vivid, clear LCD screen offering 30% greater brightness.

Development and introduction of an Internet-ready Color Personal Information Tool that can gather, create and send information, sound and images in color.

Sharp History- 5

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Development of a reflective-type Super-Mobile TFT LCD, which displays 260,000 colors in amazing clarity even in direct sunlight and with no backlight.

1997 1998

2000

Development of the world's first PlasmaclusterTM Ion air purification technology that's effective against airborne mold.

Introduction of an ultra-thin, ultra-light, B5-file size notebook PC with a large 11.3-inch TFT color LCD.

Katsuhiko Machida becomes president.

Sharp History- 6

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2001

2002 2003

Introduction of the world's first 37V*-inch LCD TV with a built-in terrestrial digital HDTV tuner.

Introduction of a 30V*-inch high-definition LCD TV with built-in digital BS HDTV tuner.

Development and introduction of the world's lightest and thinnest notebook PC with a 12.1-inch LCD.

* All screen sizes are measured diagonally.

Development of a revolutionary 3D display technology that provides a realistic sense of depth and presence.

Sharp History - 7

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Consumer Driven Change

1960s 2005

Heat Food Heat Food• Reduce Fat• Conserve Polyphenols• Conserve Energy•…

Consumer ConsciousnessHealth AwarenessEnergy Awareness

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Anywhere, Anytime Personal Health Technologies and Services

Home

Mobile

Foods (calories)

Health check MFP

Blood pressure Blood oxygen, Heart beat Sleeping

Ring sensor

Hospital & Medical network(Doctors, Inspection, Treatment, Medication ）

Implant sensor

Diet MonitoringAllergen detection

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Analyzing new opportunities- A process

Idea/Concept

TechnologyMarketBusiness Fit

Value Calculus

Decisions

Product Development

Intent

Clarity

Consumer Need

Regulation- Market

Regulation- Product

Interoperability/Stds.

+/-

+/-

+/-

+/-

+/-

+/-

Misc.

+/- Revenue Model

+/-

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Personal Healthcare Opportunities- An evaluation

Idea/Concept

TechnologyMarketBusiness Fit

Value Calculus

Decisions

Product Development

Intent

Clarity

Consumer Need

Regulation- Market

Regulation- Product

Interoperability/Stds.

++

+/?

??

??

??

Misc.

??

+ + +

Revenue Model

??

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Continua the Panacea?

Interoperability ReimbursementTest, Cert & Logo Regulation

Out of Box OperationPerformance GuaranteesEase of UseSimple Messaging

Consumer Centric Use Cases

CONTINUA

Chronic Disease ManagementAging IndependentlyWellness and Fitness

Standards SelectionTechnical GuidelinesInter-op Specs.

Definition of Reg.Pathways for PHDGeo Specific

Who pays? how much ?Geo specific

2008Logo program LaunchT&C Program Launch

2008V1 Guidelines Release

2008Work with RegulatoryAgencies

2008ReimbursementStrategies

L A B O R A T O R I E S O F A M E R I C AL A B O R A T O R I E S O F A M E R I C A

Imponderables

“ Patient Centric Healthcare-Model of Future?” Where are the economic incentives to keeping

people healthy? What is the patient really capable of? Social factors far outweigh technology capabilities? True empowerment or lip service?

Practice meets dreamscape? Changes in Doctoring- whither?

Cost and the Methodology of Care With level of service/outcomes at least as good as

current SOC, find the cheapest way to provide care => Call to regulators and policy makers.