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Lecture 9: Chapters 11 &12 Repeated Measures t - statistic & Estimation.

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Lecture 9: Chapters 11 &12 Repeated Measures t - statistic & Estimation
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Lecture 9: Chapters 11 &12

Repeated Measures t - statistic

&

Estimation

2 sample t - test 2 research strategies

– Between subjects (independent measures): 2 data sets can come from 2 completely different samples

• e.g. a sample of depressed patients treated with talk therapy and a separate sample of depressed patients treated with meditation therapy

– Within subjects (repeated measures): 2 data sets can come from the same sample

• e.g. A sample of depressed people before treatment and the same sample of depressed people after treatment.

• e.g. Dogs are given a choice between two types of dog food. Researchers measure the amount eaten of each type over a 10 min. period.

Repeated Measures Stats Within subjects: a single sample of individuals

is measured more than once on the same dependent variable. The same subjects are used in all treatment conditions

Matched sample: 2 separate samples of subjects, but each individual in one sample is matched with a subject in the other sample.– e.g. match subjects across several variables like

age, income, education, sex.

In this chapter we are going to focus on repeated measures b/c they are more common than matched subjects, but the same statistical techniques apply.

t - statistic for repeated measures Related samples t is based on

differences scores rather than raw scores (X values)

Difference score = D = X2 - X1

– e.g. X2 was obtained after treatment and X1

is the baseline condition

t = sM

M - t = MD - D

sM

t = Sample stat - pop. parameter

Estimated standard errorD

MD = mean difference score

D = unknown population difference score

sM = standard error of the difference scoresD

Hypothesis Tests for Repeated Measures(1) State the hypothesis (Remember this could also be

directional): H0 = D = 0 There is no effect, no change, no difference. According to this hypothesis, it is possible that some

individuals will show + D scores and some will show - D scores, but this will not be systematic. When averaged they will balance to 0.– e.g. your resting HR if tested every week for 8 weeks (under the same

conditions, no change in exercise regime)

H1 = D = 0 Difference scores are consistently + or -

– e.g. your resting HR is you tested every week for 8 weeks under conditions where we begin to increase cardiovascular exercise everyday

Example A researcher is investigating the effects of eating oatmeal on

cholesterol. A sample of 10 volunteers was obtained (none of whom ate oatmeal on a regular basis). Each volunteer had his/her cholesterol measured. Subjects were then asked to eat 2 cups of oatmeal each day. After 30 days their cholesterol was measured again. Does oatmeal change cholesterol levels?

Subject 1 2 3 4 5 6 7 8 9 10

H0 = D = 0 changes in cholesterol levels due to chance

H1 = D = 0 changes in cholesterol levels due to oatmeal

baseline

test

diff.

145

145

0

187

157

-30

130

119

-11

155

140

-15

152

140

-12

112

115

+3

120

111

-9

208

199

-9

167

159

-8

184

186

+2

(2) Locate the critical region All calculations for the t-statistic here are done

with difference scores and there is only 1 D score for each subject. – So, df = n-1 (n refers to the number of D

scores, not the number of X scores)

A researcher is investigating the effects of eating oatmeal on cholesterol. A sample of 10 volunteers was obtained (none of whom ate oatmeal on a regular basis). Each volunteer had his/her cholesterol measured. Subjects were then asked to eat 2 cups of oatmeal each day. After 30 days their cholesterol was measured again. Does oatmeal change cholesterol levels?

df = 9, alpha = .05 2-tailed, critical t-value = +/-2.262

Hypothesis Tests for Repeated Measures

(3) Collect data and compute the test statistic - use D scores for formulas

Subject 1 2 3 4 5 6 7 8 9 10

Hypothesis Tests for Repeated Measures

D = -8.9 SS= 836.9 s2 = 92.99 sM = 3.05

t = -8.9 - 0 / 3.05 = -2.92

t = MD - D

sM D

baseline

test

diff.

145

145

0

187

157

-30

130

119

-11

155

140

-15

152

140

-12

112

115

+3

120

111

-9

208

199

-9

167

159

-8

184

186

+2

D

Hypothesis Tests for Repeated Measures

(4) Make a decision

Our t value is -2.92 and our t-critical value was 2.262, so we can reject the null hypothesis!

Eating oatmeal significantly reduces cholesterol, t(9) = -2.92, p < .05

Directional Hypothesis Test for Repeated Measures

What would change in our previous example if we had predicted that oatmeal would lower cholesterol levels?– State hypothesis

– Locate critical region

H0 = D 0 cholesterol levels are not reduced after eating oatmeal

H1 = D < 0 cholesterol levels are reduced after eating oatmeal

df = n-1

df = 9

Alpha = .05 1-tailed

Critical value = -1.833

Measuring Effect Size d = mean difference / standard deviation

d = DM / s

From our oatmeal example:

DM = -2.92s2 = 92.99s = 9.62

D = 2.92 / 9.62 = .3Medium effect

Measuring Effect Size r2 = t2 / (t2 + df)

r2 = -2.922 / (-2.922 + 9)

r2 = .49 or 49 % of the variance

Large effect size using this measure

Matched Sample - Same Idea New reading program developed for students…want to make

sure that the one of the two samples chosen doesn’t just by chance contain better readers, so we’ll match each each group one-to-one. If student A had a reading achievement score of 75 then we’ll match the second sample with a student B that has a score of 75 as well (pre-treatment)

Matched Pair

ControlReading Program

D D2

A 6 15 +9 81

B 5 15 +10 100

C 11 17 +6 36

D 6 13 +7 49

Matched Pair

ControlReading Program

D D2

A 6 15 +9 81

B 5 15 +10 100

C 11 17 +6 36

D 6 13 +7 49

MD = 8

SS = 10

s2 = 3.33

= .91sM D

H0 = D =0 (no effect on reading comprehension)

H1 = D =0 (no effect on reading comprehension)

Matched Pair

ControlReading Program

D D2

A 6 15 +9 81

B 5 15 +10 100

C 11 17 +6 36

D 6 13 +7 49

MD = 8

SS = 10

s2 = 3.33

= .91

Set critical region for .01 2-tailed

df = n - 1 = 3 +/- 5.841

t = 8 - 0 / .91 = 8.79

Reject the null the new reading program works!

Relationship between Descriptive and Inferential Statistics

Descriptive stats should help you visualize the sample data and, so, have a better understanding of the results.– For example mood scores for depressed people before and

after meditation therapy

– MD = 12

– s = 3.6– Without even performing hypothesis testing we can see that

it looks as if the the sample is obtained from a different population of scores

0 2 4 6 8 10 12 14 16

Advantages to Repeated Measures Good when only a small N is available

– e.g. patient populations, rare species, etc. Good for questions that are looking for changes

across time– Developmental questions– Learning questions

No worry about individual differences– No worries about the difference simply being due to

individuals (e.g. in a learning study that one group was just smarter than the other group)

– Decreases sample variance (which remember the higher the variance the more difficult it becomes to see a pattern in our data)

Disadvantages Carryover effects - participant’s response in the

second treatment is altered by lingering effects of the first treatment– e.g. administering the second drug too soon after

the first Progressive error - participant’s performance

changes consistently over time– e.g. a participant improves over time simply due to

practice Counterbalancing the order treatment can help

with these problems– e.g. Subject 1 gets treatment 1 first then treatment

2. Then subject 2 gets treatment 2 first then treatment 1.

Estimation - Another Inferential Statistical Procedure

Hypothesis testing lets us know if a particular sample came from a particular population. It helps us evaluate the effect of the treatment. The treatment either has an effect or it doesn’t.– Eating oatmeal does lower cholesterol

Estimation is the process of using sample data to actually estimate the values for population parameters.– So, it will determine the value of the population mean after

treatment. It will estimate how much effect the treatment had. How big or small the effect is.

Estimation

The use of samples to estimate the population is quite common

– 42% of the population supports the president

– 8% of UA students are members of the Green Party

– 34% of Americans are homeowners

NOTE: We’ve already done estimation before. We know how to estimate the population variance from the sample variance. Using df.

2 - Types of Estimation We also know how to estimate the SE, so we know

what the average distance from our sample mean to our population mean is. So, we can begin to estimate our population mean…

Point estimation - a specific value using 1 number to estimate the population mean.– If I were to estimate the weight of my dog I’d say 100 lbs.

Interval estimation / Confidence intervals - uses a range of values to estimate the population mean. Interval estimates are usually accompanied by the probability of obtaining that range of values. This probability information is called a level of confidence. – If I were to estimate the weight of my dog I might say

between 90 and 110 lbs.

When should we estimate?(1) After a hypothesis test when H0 is rejected.

This is the case where we know there is a treatment effect, but we want to know how much. (Like the oatmeal example.)

(2) When you know there is an effect, but you want to know how much.– For instance, we probably know that tutoring will improve

grades. However, tutoring is $25 / hour. We want to know how much our grade will improve to figure out if the cost for us will be justified.

(3) We want basic information about a population– For instance, we want to know the average number of times

college students eat pizza each week.– We want to know about how many people support the war in

Iraq.

Hypothesis Testing vs. Estimation

Goal = testing null hypothesis

(1) Hypothesize about the unknown pop. parameter.

(2) Calculate z or t by substituting the hypothesized value into the formula.

(3) If get an extreme value for z or t we conclude the hypothesize value was incorrect and reject the null.

(4) An extreme value is determined by its location in the distribution. Extreme values are less probable than 5%

Goal = estimating the value of the parameter

(1) Don’t calculate z or t. Instead estimate what z or t should be if our parameter is reasonable.

(2) We usually select a z or t of 0 (or a range around 0), because this is most probable because it a highly probable value.

(3) The z or t score is inserted into the formula and we solve for the parameter.

(4) Because we chose a reasonable z or t we assume our parameter will be a reasonable estimate.

Calculating an Estimate

Unknown parameter = stat. +/- (z or t * SE)(1) We will know all the values on right side

except for z or t.(2) We don’t know the z or t score, but we do

know what the distribution looks like. We know the mean is always zero.

(3) For a point estimate best value for z or t will be 0. For an interval estimate best value will mark off the middle part of the distribution

Hi - probability outcomes for z & t. REASONABLE

Extreme lo-probability outcomes

Estimate with a z-score: point estimation

Mean grade for Latin classes at UofA were 75. We want to know how much grades improved after some students (n= 15) took tutoring. Their mean grade was 85.

Point estimate – Z = M - / M OR (because of algebra) = M +/- z(sM)

– 0 = 85 - / 2.58

– 85 = So the sample mean estimates the population mean. Because of

the Central Limit Theorem this should make sense…as n increases the sample mean should approximate the population mean.

75 = ?

10 10

Mean grade for Latin classes at UofA were 75. We want to know how much grades improved after some students (n= 15) took tutoring. Their mean grade was 85.

Confidence intervals - Commonly used levels of confidence start at 60% and go up.

Let’s use our tutoring example where we want to be 75% confident that our true population mean lies within our predicted range. (1) Determine the z-scores which bind 75% of the distribution (we should

have 25% of the distribution left in the tails of our distribution (so .25 / 2 = .125 and the z-score associated with .125 in the tail column of our unit normal table is +/- 1.16

(2) Estimate the population means: Z = M - / M OR (because of algebra) = M +/- z*(sM)

Estimate with a z-score: confidence intervals

So, if we randomly pulled a sample 75% of the sample means would be between 82.01 and 87.99

1.16 = 85 - / 2.58 -1.16 = 85 - / 2.58 = 82.01 = 87.99

Interpreting a Confidence Interval Population mean = sample mean +/- some error

What do we know from our confidence interval?– The sample mean 85 is located somewhere in our

distribution of sample means.– Although we do not know the exact location of that

sample mean we can be 75% sure that it is between a z-score of +/- 1.16

– If we took additional samples 75% of the time they would be located between z-scores of +/-1.16

– And as long as the sample mean is located in the middle 75% of the distribution, the interval will contain the population mean

Let’s Try One A farmer is interested in increasing his corn

yield. He read about a new fertilizer that is purported to increase yield. Before spending the money to fertilize all his fields he decided to test the fertilizer on 2 fields. The average yield of corn without the fertilizer is 150 bushels with a standard deviation of 25. The average yield on his sample 2 fields was 190 bushels.– Make a point estimate– Make an interval estimate of the population mean,

so that you are 80% sure that the true mean is in your interval

Answers Point estimate:0 = 190 - / 17.67 = 190

Confidence Interval* z-scores that bind 80% of the distribution are (20% left in the tails, so 10% in each tail) = +/- 1.29

1.29 = 190 - / 17.67 = 167.21 -1.29 = 190 - / 17.67 = 212.79

So, the we are 80% sure that the population mean for the

amount of corn harvested after treatment with a fertilizer is between 167.38-212.62. Should we buy the fertilizer?

Estimation with a single-sample t Convert the t-statistic so that :population mean = sample mean +/- t * standard error

Single sample t : = X +/- (t * sM) Same rules only now, we are estimating a value

or range of values for t– Estimate where the sample data are located in the t

distribution• Most likely value = 0 for point• For interval the exact range will determine our t values.

– The sample mean and standard error (both computed from our sample) AND our estimated t value gets plugged into the formula

Point estimate with a single sample t A toy manufacturer asks a developmental

psychologist to test children’s responses to a new product. Specifically, the manufacturer wants to know how long, on average, the toy keeps the child attention. A sample of 9 children is taken the psychologist’s measure the amount of time they play with the toy. Sample mean = 31 min. and SS of 648.

t = X - / sM or = X +/- (t * sM)

NOTE: We aren’t applying a treatment here, so we aren’t trying to estimate the treatment effect size, only the population mean.

SS = 648

s2 = SS / df, so s2 = 81

s = s2, so s = 9

sM = s / n , sM = 3

0 = 31 - / 3

= 31

Confidence Intervals with a single sample t

A toy manufacturer asks a developmental psychologist to test children’s responses to a new product. Specifically, the manufacturer wants to know how long, on average, the toy keeps the child attention. A sample of 9 children is taken the psychologist’s measure the amount of time they play with the toy. Sample mean = 31 min. and SS of 648 min.

t = X - / sx or = X +/- (t * sM)

The toy manufacturer decides they want a confidence

interval of 95%. So, we need to find the t values the would form the boundaries of the 95%, so we need to look for the critical t-value when .05 is our proportion in 2 tails. We also need to account for df, which is 8.

Our critical t values are +2.306 and -2.306

Confidence Intervals with a single sample t

A toy manufacturer asks a developmental psychologist to test children’s responses to a new product. Specifically, the manufacturer wants to know how long, on average, the toy keeps the child attention. A sample of 9 children is taken the psychologist’s measure the amount of time they play with the toy. Sample mean = 31 min. and SS of 648 min.

t = X - / sx or = X +/- (t * sM)

Our critical t values are 2.306 and -2.306

Estimate the range of our population mean2.3 = 31 - / 3

6.9 = 31 -

= 24.2

-2.3 = 31 - / 3

-6.9 = 31 -

= 37.9

Let’s Try One You want to know how many times on

average college students order pizza a month. You take a sample of 25 college students and find that they on average ordered pizza 1.8 times per week with a SS of 326.

Do a point estimate

Calculate a confidence interval of 90%

Independent-Measures 1 - 2 = (M1 - M2) +/- ts(M-M)

Let’s compute a point estimate and a confidence interval using 95% confidence interval

Sample 1 Sample 2

n = 10 n = 5

M = 25 M = 33

SS = 250 SS = 140

(M1 - M2) - (1 - 2) t = sM1 - M2

Repeated Measures D = MD +/- tsM

Let’s compute a point estimate and a confidence interval using 90% confidence interval

MD = 21

SS = 1215 n = 15

D

t = MD - D

sM

Factors affect CI width To gain more confidence in your

estimate you must increase the width The larger the level of confidence (%)

the larger the t value and the larger the interval

Interval width decrease as n increases– Bigger sample gives more info about the

population, so we can make a more precise estimate

– Sample size controls the magnitude of standard error

Homework

Chapter 11:– 1, 2, 3, 7, 9, 10, 11

Chapter 12:– 1, 3, 5, 6, 9, 10, 12


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