Lectures on respiratory physiologyLectures on respiratory physiology

Mechanics of Breathing IMechanics of Breathing I

Perfect Lung

Action of the diaphragm

Perfect Lung

Action of the intercostal muscles

Perfect Lung

Action of the abdominal muscles

Perfect Lung

Action of the intercostal muscles

Perfect Lung

Pressure-volume curve of the lung

3000

2000

1000

FRC

0 -10 -20 -30

Intrapleural pressure (cmH2O)

Vo

lum

e a

bo

ve

FR

C (

ml)

COMPLIANCE = ΔV / ΔP

=1000/5

= 200 ml/cmH2OΔV

ΔP

Compliance of lung

Perfect Lung

Capillary showing collagen (Col)

Perfect Lung

Fibers of elastin

Perfect Lung

Some effects of surface tension

Perfect Lung

Comparison of air and saline inflation

Perfect Lung

Measurement of surface tension and its behavior

Perfect Lung

Comparison of air and saline inflation

Type II alveolar epithelial cell

Type II cell showing lamellar inclusion bodies (LIB)

Lung with absence of surfactant

Regional differences of ventilation at FRC

Regional differences of ventilation at RV

Alveoli are larger at the apex (upper panel) than base (lower)

Airway closure at the lung base

Pressure changes with bilateral pneumothorax

Pneumothorax of right lung

Fibrosis of right lung

Relaxation pressure-volume curves

Perfect Lung

Pressure-volume curve of the lung

Relaxation pressure-volume curves