LegActifNatural ingredient
for the treatment of tired legs
Blood circulation stimulator
Technical specifications
LegActif 7234
PROPERTIES Blood circulation stimulatorIncreases blood circulation by 31%
Anti-edema. Edema reduction:Reduced skin thickness by 0.45 mm.Reduced leg contour by 0.5 cm and calf contour by 0.3 cm.
ACTIVE MOLECULES Goldenrod extract (rutin)Lemon peel extract (naringin and hesperidin)Butcher's broom extract (ruscogenin)
APPEARANCE LiquidColor: very dark brown
SOLUBILITY Soluble in aqueous solutions
RECOMMENDEDDOSE 0.5-1.5%
Formulation
Revitalizing gel for tired legs
A
B
C
D
INCI / PCPC
Acrylates/ C10-30 Alkyl Acrylate CrosspolymerGlycerinAqua (Water)Disodium EDTAPreservative
TriethanolamineAqua (Water)
LEGACTIFTM
Oleth-20Parfum (Fragrance)Aqua (Water)Preservative
TriethanolamineAqua (Water)
% (w/w)
0.405.00
86.050.100.80
0.051.00
1.500.650.303.000.50
0.250.40
provitalgroup.com
LegActif
LegActif is a complex ofplant active ingredients(Goldenrod, Lemon andButcher's broom) aimed atrelieving tiredness andheaviness in the legs.
Toxicological information
This product has been evaluated according to theavailable toxicological information, based on safetyassays and bibliographical data. These data allowthe conclusion that using this ingredient, under thenormal conditions for the use of cosmetics and atthe recommended concentrations, is free of risks.
Cosmetic applications
Products for the treatment of tired legs.LegActif stimulates blood circulation, thusrelieving leg heaviness. Its anti-edemaactivity further provides calming,decongestant and anti-fatigue effects.
Edema reduction
Images correspond to one of the LegActif-treatedvolunteers.
LegActif reduced skin thickness by 0.45 mm, whichdemonstrated edema reduction.
Initial situation Final situation
Ultrasound images:
Centimetric measurements
-0.50
-0.40
-0.30
-0.20
-0.10
0.00
Red
uctio
nfro
m D
0 (c
m)
Legactif - calfPlacebo - calf
-0.50
0.00
Centimetric measurements
LegActif-treated volunteers showed clear 0.5 cm reductionin calf contour.
Qualitative evaluationQuestionnaire
90% of the volunteers reported immediate comfort after application.
80% of the volunteers reported reliefof leg tiredness.
70% of the volunteers reported decongestant effect.
70% of the volunteers reported longterm wellness.
Study carried out on:The legs of 10 volunteers treated with LegActif 1.5% and 10 volunteers treated with a Placebo.Two weeks, two daily applications.
Evaluated by using:Laser Doppler, Ultrasonography, Centimetricmeasurements and self-evaluation questionnaire.
Laser Doppler measurements: clear-cut improvement in blood circulation
Laser Doppler Flowmetry
Legactif 1.5%Placebo
-10
0
10
20
30
40
% v
aria
tion
as c
ompa
red
to C
ontr
ol
2.27% 1.27%
30.94%
-3.38%
D0 D14
LegActif-treated volunteers showed clear improvementin blood circulation. Blood flow increased by 31%as compared to Control.
In Vivo
Goldenrod(Solidago virgaurea L.)
Lemon(Citrus limonum L.)
Butcher's broom(Ruscus aculeatus L.)
Features and benefits
LegActif is a cosmetic active ingredient effective in thetreatment of tired legs. Its activity results from the combinedactions of its active principles: naringin, hesperidin, rutinand ruscogenin, which stimulate blood circulation andreduce edema.
Goldenrod
Lemon
Butcher’sbroom
LegActif
Component Active principle Main action
Rutin
Naringin andHesperidin
Ruscogenin
Anti-edema
Anti-edema
Blood circulationstimulator
LegActif action mechanism