21
AMINO ACID AND PROTEIN STRUCTURE To know the chemical reactions involved in the formation of proteins To know the types of bond formed when proteins fold
AMINO ACID AND PROTEIN STRUCTURE
To know the chemical reactions involved in the formation of proteins
To know the types of bond formed when proteins fold
AMINO ACIDS (PRIMARY STRUCTURE)… 20 different amino acids Different ‘R’ groups Form hydrogen, covalent and ionic bonds as
well as hydrophobic and hydrophillic interactions between R-groups
Removed as urea Amine Group
Acid Group
AMINO ACIDS (PRIMARY STRUCTURE)… 20 different amino acids Different ‘R’ groups Form hydrogen, covalent and ionic bonds as
well as hydrophobic and hydrophillic interactions between R-groups
Removed as urea Amine Group
Acid Group
CONDENSATION TO FORM A ‘DIPEPTIDE’… Amino group + carboxyl group Forms a peptide bond (C – N) Amino acids dipeptide + water
HYDROLYSIS OF A DIPEPTIDE… Dipeptide + water amino acids
Complete qus 1-3 pg 22
FORMING A POLYPEPTIDE (PROTEIN)…
EXPLAIN WHY THIS HAPPENS…
LEVELS OF PROTEIN STRUCTURE…
Level of structure
Types of structure
Bonds in structure
Description of shape
Primary (1°)
Secondary (2°)Tertiary (3°)
Quaternary (4°)
Complete using pgs 19-21
F212: 2.1.1 B-EKEY EXAMPLES OF MAMMALIAN PROTEINS
HOW WOULD YOU BUILD AN ENZYME?
HAEMOGLOBIN...
COLLAGEN...
EXAM QUESTIONS... Notes/table to compare structure and
properties of collagen and haemoglobin PG 149 QU 4 – COLLAGEN & CELLULOSE QU 6c,d – ENZYME STRUCTURE
