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Lesson 6 neurotransmitter interuption

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Lesson 6 – Interference of Neurotransmitter function VCE PSYCHOLOGY © Kristy Kendall & Edrolo 2016 Study design dot point the effects of chronic changes to the functioning of the nervous system due to interference to neurotransmitter function, illustrated by the role of GABA in Parkinson’s disease. What you need to know and be able to do: Explain the symptoms of Parkinson's disease Explain the role of GABA in Parkinson's disease Explain the role of Dopamine in Parkinson's disease
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Page 1: Lesson 6   neurotransmitter interuption

Lesson 6 – Interference of Neurotransmitter function

VCE PSYCHOLOGY

© Kristy Kendall & Edrolo 2016

Study design dot point• the effects of chronic changes to the functioning of the nervous system

due to interference to neurotransmitter function, illustrated by the role of GABA in Parkinson’s disease.

What you need to know and be able to do:• Explain the symptoms of Parkinson's disease• Explain the role of GABA in Parkinson's disease • Explain the role of Dopamine in Parkinson's disease  

Page 3: Lesson 6   neurotransmitter interuption

Neurotransmitter interruption

© Kristy Kendall & Edrolo 2016

• Neurotransmitter interruption can occur from an imbalance or deficiency in a particular type of neurotransmitter.

• Causes of neurotransmitter interruption may be naturally occurring or self induced. Common causes include:– Alcohol and drugs– Diet and nutrition– Stress– Genetics

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• The side effects are many and varied, some can be permanent and others short term. All relate directly to the type of neurotransmitter impacted. Some side effects include:

• Some of these effects are chronic, while others are temporary

© Kristy Kendall & Edrolo 2016

Mental HealthDisorders

Addiction Immobility Weight Lossor Gain

Side effects of neurotransmitter interruption

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© Kristy Kendall & Edrolo 2016

• Neurotransmitter deficiencies can in many cases be treated through drugs and medication, artificially replacing the lost neurotransmitter.

• The biggest problem with this is that it does not help the natural production, in fact in can suppress it further.

Treating neurotransmitter interruptions

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Deficiency in serotonin• Serotonin is an inhibitory neurotransmitter that involves stabilising

mood.• Without it individuals suffer emotional disturbances that can result

in schizophrenia.

© Kristy Kendall & Edrolo 2016

Page 7: Lesson 6   neurotransmitter interuption

Deficiency in dopamine• Dopamine is an excitatory neuron involved in drive, motivation and

motor movement.• Without it, individuals can suffer from depression.

© Kristy Kendall & Edrolo 2016

Page 8: Lesson 6   neurotransmitter interuption

What is Parkinson’s disease• Parkinson’s disease is a progressive degeneration of the nervous

system characterised by tremor and muscle rigidity.

© Kristy Kendall & Edrolo 2016

https://www.flickr.com/photos/pahudson/6719675893/in/photostream/Michael J Fox - speaking at Lotusphere 2012Paul Hudson

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Video source:https://www.youtube.com/watch?v=ECkPVTZlfP8MJ Fox interview (2.15 min)

© Kristy Kendall & Edrolo 2016

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What causes Parkinson’s disease?• Low levels of dopamine – causes movement problems• Low levels of GABA have now also been found which explains why

dopamine treatments (such as L-dopa) only have short term effects

Further reading:https://hms.harvard.edu/news/challenging-parkinsons-dogma-10-24-12

© Kristy Kendall & Edrolo 2016

Page 11: Lesson 6   neurotransmitter interuption

Exit Questions

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Fast five - Question 1What does the term chronic mean?

© Kristy Kendall & Edrolo 2016

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Fast five - Question 1 (Answer)What does the term chronic mean?

Answer:Long time.

© Kristy Kendall & Edrolo 2016

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Fast five - Question 2Name two ways that neurotransmitters can be interrupted.

© Kristy Kendall & Edrolo 2016

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Fast five - Question 2 (Answer)Name two ways that neurotransmitters can be interrupted.

Answer:Alcohol and stress.

© Kristy Kendall & Edrolo 2016

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Fast five - Question 3Name two side effects of neurotransmitter interruption.

© Kristy Kendall & Edrolo 2016

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Fast five - Question 3 (Answer)Name two side effects of neurotransmitter interruption.

Answer:Mental health problems and weight gain.

© Kristy Kendall & Edrolo 2016

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Fast five - Question 4Name two neurotransmitters that are linked to the onset of Parkinson’s disease.

© Kristy Kendall & Edrolo 2016

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Fast five - Question 4 (Answer)Name two neurotransmitters that are linked to the onset of Parkinson’s disease.

Answer:Dopamine and GABA.

© Kristy Kendall & Edrolo 2016

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Fast five - Question 5What is Parkinson’s disease?

© Kristy Kendall & Edrolo 2016

Page 21: Lesson 6   neurotransmitter interuption

Fast five - Question 5 (Answer)What is Parkinson’s disease?

Answer:Progressive degeneration of the nervous system.

© Kristy Kendall & Edrolo 2016


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