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Diska Astarini
I11109083
LEUKOCORIA
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DEFINITION
LeukocoriaA wite !u!i""ar# re$e% &"eukos'
wite( kore' !u!i")( !ink*wite( or#e""ow*wite !u!i""ar# re$ection+
Nor,a" re$e% re- re$e%
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Nor,a" re- re$e%
Leukocoria .i"atera" Leukocoria uni"atera"
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Clinical
diferentials?
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Leucocoria
• TUMOR
–Retinoblastoma (most common cause--58%)
• D!LO"M#T$L
–"ersistent &'er'lastic 'rimar& itreous• (nd most common cause--8%)
–Coats disease (*+%)
–Retrolental ,bro'lasia (--5%)
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• .#/CT.O# –Laral 0ranulomatosis (*+%)
• D1#R$T.! –cataract
• TR$UM$ –Retino'at& o2 'rematurit& (5%)
–Lon0-standin0 retinal detacment
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RETINO/LATOARetino."asto,a is te ,ostco,,on intraocu"ar ,a"i2nantneo!"as, o ci"-oo- a4ectin2
1'50(000 to 1'36(000 ci"-ren+Te tu,or occurs ,ostre7uent"# witin te rst 5#ears o "ie an- ,a# een .e
oun- at .irt+
i2ns' "eukocoria( stra.is,us(!oor ision( s!ontaneous#!e,a( or a re-( !ainu" e#e+
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RETINO/LATOAA /
C
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RETINO/LATOAA /
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RETINO/LATOATreat,ent o!tion'
• Intraenous ce,otera!#• Enuc"eation
• Ra-iation tera!#• Lasertera!#• Cr#otera!#
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RETINO/LATOA * Ce,otera!#
PRETREATMENT
a,e "esion atertwo c#c"es o
ce,otera!#
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TO;OCARIAITo%ocariasis a ne,ato-einection (Toxocara canis)
Retina" -a,a2e is te resu"t o teost
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TO;OCARIAI
=resent 'Occu"ar s#,!to,s ' re-ness(!oto!o.ia > !ain+
Leukocoria( stra.is,us( -ecrease-ision( $oaters+
O!ta",ic !#sica" e%a,ination '
A "ar2e !eri!era" &anterior)retina" or coroi- in$a,,ator#,ass( associate- wit aitreoretina" reaction secon-ar#retina" -etac,ent+
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TO;OCARIAI
A white intravitreous mass of a
toxocaral eosinophilic granuloma
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CATARACTCataract an# o!acit# in te "ensFactors ' a2in2( trau,a( to%ins(s#ste,ic -isease &suc as
-ia.etes)( s,okin2( an- ere-it#+
Ci"-oo- con2enita" cataractsi2n '
"eukocoria a.sent re- !u!i""ar# re$e% a.nor,a" e#e ,oe,ents&n#sta2,us) tra.is,us
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COAT? DIEAECon0enital retinal telan0iectasis(Coats3 disease) is an idio'aticretinal ascular disorder tat usuall&
afects &oun0 male 'atientsunilaterall& in teir ,rst or seconddecade o2 li2e4 No tu,or ,ass+ Retinal telan0iectasia4
Retinal ca'illar& non'er2usion4 Dilated interca'illar& s'aces4 Li'id e6udate4 7ubretinal uid Retinal detacment
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COAT? DIEAEA
A+ Coat?s -isease in ci"-ren/+ ascu"ar a.nor,a"ities wit
aneur#s,a" -i"atation(
te"an2iectasia( e%u-ation( an-seere "i!i- -e!osition in te
/
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COAT? DIEAE * Treat,ent
"otocoa0ulation Cr&otera'&
nucleated later sta0e seere
Obliterate
telangiectasia
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ETINO=AT@ OF =REATURIT&RO=)
• Retino'at& o2'rematurit& (RO") 9as2ormerl& :no9n as
retrolental ,bro'lasia4• Disorder o2 te
deelo'in0 retinalasculature resultin02rom interru'tion o2normal 'ro0ression o2ne9l& 2ormin0 retinalessels4
•
Occurs in teincom letel
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RIK FACTOR
• 'rematurit& < lo9 0estational a0e = > 9ee:s• Lo9 birt 9ei0t•
&'ero6ia < &'o6ia• i0 Li0t e6'osure• !itamin de,cienc&
• "ostnatal se'sis• Mecanical entilation
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RETINO=AT@OF =REATURIT &RO=)
LOCATION Bone 1 *
centre- on-isc( 5% -isc
to oea-istance
Bone 5 * outer"i,it e7uator
te,!ora""#(ora nasa""#
Bone 3 *te,!ora"
!eri!era"crescent
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RETINO=AT@OF =REATURIT &RO=)
Treatment @• Laser 'otocoa0ulation• Cr&otera'&• !itrectom& sur0er&
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TENT @=ER=LATIC =RIARU &=@=)
"ersistent &'er'lastic 'rimar&itreous (""!) is a con0enitalanomal& in 9ic te 'rimar&itreous 2ails to re0ress in utero4
i0l& ascular mesenc&mal tissuenurtures te deelo'in0 lens durin0intrauterine li2e4 .n ""!A temesenc&mal tissue (,broascular)2orms a mass beind te lens4
$ 0ra&-&ello9 retrolental membranema& 'roduce leu:ocoriaA 9it tesubseBuent sus'icion o2
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=ERITENT @=ER=LATIC=RIAR
ITREOU &=@=)i2n 'Leukocoria,a"" e#e &,icro!ta",ia)
E!iso-es o intraocu"ar&intraitreous) e,orra2e+
Retina" -etac,ent traction ro, .roascu"ar
,ass+
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NORRIE? DIEAE#orrie diseaseA or te 'ro0ressieoculoacousticocerebral de0enerationo2 #orrieA is a rareA -lin:ed recessie
eritable disorder caracteri;ed b&bilateral leu:ocoria caused b& retinaldetacment4$fected bo&s classicall& ae a triad
o2 blindnessA dea2nessA and mentalretardation4 $''arent at birt or inearl& in2anc&A te ocular ,ndin0susuall& 'ro0ress to 'tisis bulbi4
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RETINAL DETAC@ENT$ retinal detacment (RD)
describes te se'aration o2 teneurosensor& retina (#7R) 2romte retinal 'i0ment e'itelium
(R") caused b& a brea:do9n o2te 2orces tat attac te #7R tote R"4
To%ocariasis( =@=( RO=(Coat?s -isease
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RETINAL DETAC@ENT
Treatment@•Cr&otera'&• laser 'otocoa0ulation usin0 a
slit-lam' delier& s&stem and• laser usin0 te indirecto'talmosco'ic delier& s&stem
combined 9it scleral indentation4
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CONCLUION
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T@ANK OU
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UETION
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