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LIPID TRANSPORT
Lipoproteins• Lipids are transported in the blood as
lipoproteins• are soluble in water because the surface
consists of polar lipids.
2Lipid transport
Apolipoproteins +
Lipids:
Cholesterol
Cholesteryl esters
Triacylglycerols
Phospholids
lipoproteins
• Combine lipids with proteins and phospholipids.
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• The lipoprotein formed depends on the constituent protein and lipids
There are 4 types of lipoprotein
triglyceride
protein
Chylo VLDL LDL HDL
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Composition of lipoproteins
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7Lipid transport
TGTG
TGTGTG
TGTG
Bile salts
(emuslification)
TG
Fatty acidsglycerol
INTESTINE INTESTINALEPITHELIAL
CELL
TG
Cholesterol
apolipoproteins
LYMPH/BLOOD
chylomicrons
Lipases
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LIVER
Lipid transport
ADIPOSE MUSCLE
VLDLTGCholesterolCholesterol-esters
TGTG
LDLCholesterolCholesterol-esters
TGCholesterol
CMCONS
HDLCholesterol-esters
TISSUES
GONADS
ADRENALS
lymph
Fatty acidsalbumin
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Fat cell