8/14/2019 Llipid Metabolism Lecture for 2nd year MBBS by Dr Sadia Haroon

1/14

MLFO 7;2 ) E}! Usbf

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@L[LE_:

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BAE BUGH]F_O@H]F_L_

8/14/2019 Llipid Metabolism Lecture for 2nd year MBBS by Dr Sadia Haroon

2/14

8/14/2019 Llipid Metabolism Lecture for 2nd year MBBS by Dr Sadia Haroon

3/14

Nlcx}h =! _luh fn ehnhou

la bmhub`l{f{}fuhlahilb

Bmshaoh fn og|`filo}fas, ^@E@s, @E@s

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_gf}u&ihelxi ogbla NNB b}h {}fohsshe

Ughsh NNB {}f~leh u}hbuihau ~lb lao`xslfa

la s|aughslzhe UBCs

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mbods x{ bmsf}{ulfa {}fohss

IlwheIloh``hs:

M57

Ofbulac lug

b{f`l{f{}fuhla

'UU[)u}basnh},

U}lbo|`c`|oh}f`

_gf}u&ihelxi

ogbla NNB

Og|`filo}fa

NNB,=IC

}hhsuh}lnlobulfa

W

8/14/2019 Llipid Metabolism Lecture for 2nd year MBBS by Dr Sadia Haroon

4/14

@E@

OH

@E@

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haefo|ufl

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`buh haefsfih

OH ogf`hsuh}f`n}hh {ff` fn

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A[O)2

ihelbuhe

u}banh}

@E@ }hoh{uf}

|aughl

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bole f} uh}fle

BOBU

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m| ogf`huh}f`

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OH OH

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uf {xi{ ogf`huh}f`

bo}f ugh ihim}bah,

B{f B2 }hoh{uf}

OH uf}he

la e}f{`hu

uf ugh `l~h} nf} {}fohlac

BOHG

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Sf`iba elhbhA[O elhbh

Ubaclh}

'g|{f`l{lehilb,

NGO 'u|{h LL,

8/14/2019 Llipid Metabolism Lecture for 2nd year MBBS by Dr Sadia Haroon

5/14

=;

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sufahaf}ib`

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( @holugla( Ogf`hsuh}f`

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ofi{flulfa

Ml`h _b`u @holugla Ogf`hsuh}f`

Af}ib` 7;( 28( 8(

Nlcx}h 5! [gbh elbc}bi fn ugh

{}f{h}ulh fn ug}hh ibjf} ofi{fahau

la gxiba cb``m`beeh} ml`h

@f ml`h sb`us `fh} bml`lu| uf elssf`~h ogf`hsuh}f` cb``sufahs

Ml`h _b`u @holugla Ogf`hsuh}f`

Af}ib` 7;( 28( 8(

Cb``ufah'u|{lob`,

>7( ==( 2;(

8/14/2019 Llipid Metabolism Lecture for 2nd year MBBS by Dr Sadia Haroon

6/14

Ogf`huh}f` |aughl

Bohu|` OfB

GIC)OfB

GIC)OfB

}hexoubsh Ih~b`fabuh

WB

Oh``x`b} Ogf`huh}f`

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uh}fle gf}ifah& ~lubila E |aughl

Elhub}|

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~lb `l~h} |aughl

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OH la GE@

Hsuh}lnlobulfa&}hif~b` m| @OBU&GE@

@l~h} x{ubdh

~lb b{f H

}hoh{uf}

Ml`h Bole'`l{le bmf}{ulfa,

Ogf`huh}f`

hwo}hulfa b

ml`h boleW

M

Ogf`huh}f` la `l~h}{b}u`| ihubmf`lzhe

Nlcx}h 8! _xiib}| fn ogf`hsuh}f` ihubmf`lsi!

B, M }h{}hshau nhhembod }h{}hsslfa fn ughsh haz|ihs

8/14/2019 Llipid Metabolism Lecture for 2nd year MBBS by Dr Sadia Haroon

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8/14/2019 Llipid Metabolism Lecture for 2nd year MBBS by Dr Sadia Haroon

8/14

Og|`filo}fa

]hiabau

H]hoh{uf}

Ibux}h

GE@

@bod fn `l~h} o`hb}baoh fn ogf`hsuh}f` la

u|{h LLL g|{h}`l{lehilb

WW

H

]hoh{uf}

Nlcx}h 3! Ehnhou la u|{h LLL g|{h}`l{lehilb ogb}bouh}lzhe m|

booxix`bulfa fn og|`filo}fa }hiabaus, GE@s bae LE@s 'afu

sgfa exh uf ehnhoul~h b{f`l{f{}fuhla H f} b{f H }hoh{uf}!

H

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8/14/2019 Llipid Metabolism Lecture for 2nd year MBBS by Dr Sadia Haroon

9/14

U\[H L^ G\[H]@L[LEHILB

ifsu ofiifa g|{h}`l{lehilb

lao}hbshs la mfug u}lbo|`c`|oh}f` bae ogf`hsuh}f`

afu exh uf ehnhous la `l{f{}fuhla {}fohsslac

^@E@ `h~h`s

m| f~h}{}fexoulfa ) fmhslu|, b`ofgf` bmxsh, elbmhuhs

Elbmhuhs:

obaafu sgxuefa gf}ifah shaslul~h `l{bsh ifml`lzh NNBNNB `l~h}UBCs^@E@ ol}ox`bulfa^@E@ {bugf`fclob``| hwohssl~h @E@

laolehaoh fn OBE h`h~buhe la b`` U|{h L^ g|{h}`l{lehilo {bulhaus

8/14/2019 Llipid Metabolism Lecture for 2nd year MBBS by Dr Sadia Haroon

10/14

[bugfchahsls

Fwlebulfa fn @E@

Fwlelzhe @E@

2! X{ubdh m| -ob~hach} }hoh{uf}- fa

ibo}f{gbch ugbu la~beh b}uh}| sb``4mhofih nfbi oh``

=! H`lolu OH eh{flulfa la b}uh}| sb``

?! Bugh}fo`h}fl&OBE oba eh~h`f{

@E@

Nlcx}h 7! Nhbux}hs fn fwlelzhe @E@ '}h~lh

8/14/2019 Llipid Metabolism Lecture for 2nd year MBBS by Dr Sadia Haroon

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Nlcx}h

_x{{}hsslfa fn {`buh`hu bcc}hcbulfa m| e}xc f} elhub}| lauh}~haulfa

ubdha n}fi Nlc! 3, `houx}h ?;

[CL= UWB=

Af}ib` [g|lf`fc|

@fs efh b{l}la lauh}~haulfa

Dafod efsa {`buh`hu UWB=

[CL=

UWB=

nb~f} {`buh`hu

elbcc}hcbulfa

[CL?

UWB?

Elhub}| ? nbuu| bole

lauh}~haulfa 'of`e sbuh} nlg,

[CL? boul~lu| 11 UWB?

nb~f} {`buh`hu

elbcc}hcbulfa

[`buh`hu_iffug

Ixso`h Oh``

Haefugh`lb` Oh``M`ffe ^hssh` Sb``

UWB=&

UWB?

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GHB@UG\

8/14/2019 Llipid Metabolism Lecture for 2nd year MBBS by Dr Sadia Haroon

12/14

Lajx}|: obughuh}

ux}mx`haoh huo!

Bcc}hcbuhe

[`buh`hus

Lajx}|

[CL= UWB=

[`buh`hu_iffug

Ixso`h Oh``

Haefugh`lb` Oh``M`ffe ^hssh` Sb``

GHB@UG\

UWB=

[CL=

lajx}| EBIBCHE

Lajx}|

]hhaefugh`lb`lzbulfa

Nlcx}h

Lajx}| `hbelac uf {`buh`hu bcc}hcbulfa

nf} fxae ghb`lac

ubdha n}fi Nlc! >, `houx}h ?;

8/14/2019 Llipid Metabolism Lecture for 2nd year MBBS by Dr Sadia Haroon

13/14

Bcc}hcbuhe

[`buh`hu

Ibo}f{gbch la~blfa

OH `beha iffug ixo`h

oh``4 {}f`lnh}bulfa

ulix`buhe m| [ECN .

H)2 'x{{}hhe m|

{f`|{ghaf` la }he slah,

OH `beha

ibo}f{gbch

'-nfbi oh``-,

[CL=UWB=

Ebibche haefugh`lxi

n}fi glcg M[ [CL?fwlelzhe @E@&OH

'glcg bu nbu . ogf` la

elhu, ifdlac huo!

EBIBCHEBugh}f)

so`h}fsls

[`buh`hu_iffug

Ixso`h Oh``

Haefugh`lb` Oh``M`ffe ^hssh` Sb``

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[CL=

_ifdlac fwlebau f} gfifo|uhlah

Glcg M[4 Glcg elhub}| ogf`&bu nbu

Nlcx}h

Nbouf} `hbelac uf {`buh`hu bcc}hcbulfa

la bugh}fo`h}fulo {`brxh

8/14/2019 Llipid Metabolism Lecture for 2nd year MBBS by Dr Sadia Haroon

14/14

Bcc}hcbuhe

[`buh`hu

Ibo}f{gbch la~blfa

OH `beha iffug ixo`h

oh``4 {}f`lnh}bulfa

ulix`buhe m| [ECN .

H)2 'x{{}hhe m|

{f`|{ghaf` la }he slah,

OH `beha

ibo}f{gbch

'-nfbi oh``-,

[CL=

UWB=

Ebibche haefugh`lxi

n}fi glcg M[ [CL?fwlelzhe @E@&OH

'glcg bu nbu . ogf` la

elhu, ifdlac huo!

EBIBCHEBugh}f)

so`h}fsls

[`buh`hu_iffug

Ixso`h Oh``

Haefugh`lb` Oh``M`ffe ^hssh` Sb``

GHB@UG\

UWB=&?

[CL=&?

[b}ulb` }h~h}b`&{}h~haulfa fn bcc}hcbulfa

bae `l{le booxix`bulfa m| elhu ' ? NB4 `fs

ogf`

. bu nbu, bae e}xc ugh}b{| '`fs efh b{l}la

baulfw ~lubila ogf` `fsh}lac e}xc,

Nlcx}h

Nbouf} `hbelac uf }h~h}b` f} {}h~haulfa

fn {`buh`hu bcc}hcbulfa