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Luca Botta MD, Cardiac Surgery Unit Niguarda Cà Granda Hospital, Milan, Italy Partial aortic root...

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Luca Botta MD, Cardiac Surgery Unit Luca Botta MD, Cardiac Surgery Unit Niguarda Cà Granda Hospital, Milan, Niguarda Cà Granda Hospital, Milan, Italy Italy Partial aortic root remodeling Partial aortic root remodeling with selective replacement of the non-coronary sinus: with selective replacement of the non-coronary sinus: does aortic valve morphology influence outcomes? does aortic valve morphology influence outcomes? L L , Cannata A, Bruschi G, Trunfio S, Merlanti B, Russo CF, Taglieri C, Martin
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Page 1: Luca Botta MD, Cardiac Surgery Unit Niguarda Cà Granda Hospital, Milan, Italy Partial aortic root remodeling with selective replacement of the non-coronary.

Luca Botta MD, Cardiac Surgery Unit Luca Botta MD, Cardiac Surgery Unit Niguarda Cà Granda Hospital, Milan, ItalyNiguarda Cà Granda Hospital, Milan, Italy

Partial aortic root remodeling Partial aortic root remodeling with selective replacement of the non-coronary sinus: with selective replacement of the non-coronary sinus: does aortic valve morphology influence outcomes?does aortic valve morphology influence outcomes?

Botta LBotta L, Cannata A, Bruschi G, Trunfio S, Merlanti B, Russo CF, Taglieri C, Martinelli L.

Page 2: Luca Botta MD, Cardiac Surgery Unit Niguarda Cà Granda Hospital, Milan, Italy Partial aortic root remodeling with selective replacement of the non-coronary.

Luca Botta MD, Cardiac Surgery Unit Luca Botta MD, Cardiac Surgery Unit Niguarda Cà Granda Hospital, Milan, ItalyNiguarda Cà Granda Hospital, Milan, Italy

These aneurysms begin in the ascending aorta and extend into the root and arch. The pattern of root dilation is determined by pressure and flow characteristics. The sinotubular junction (STJ) enlarges first followed by the noncoronary and right coronary sinuses. Though the annulus remains stable, the respective valve cusps are retracted and splayed producing central aortic regurgitation. The left coronary sinus usually retains normal dimensions until a very advanced stage, except in patients with sitis inversus where the left sinus dilates first.

Page 3: Luca Botta MD, Cardiac Surgery Unit Niguarda Cà Granda Hospital, Milan, Italy Partial aortic root remodeling with selective replacement of the non-coronary.

Luca Botta MD, Cardiac Surgery Unit Luca Botta MD, Cardiac Surgery Unit Niguarda Cà Granda Hospital, Milan, ItalyNiguarda Cà Granda Hospital, Milan, Italy

Ascending Aorta and Isolated Non-Coronary Sinus Replacement

Page 4: Luca Botta MD, Cardiac Surgery Unit Niguarda Cà Granda Hospital, Milan, Italy Partial aortic root remodeling with selective replacement of the non-coronary.

Luca Botta MD, Cardiac Surgery Unit Luca Botta MD, Cardiac Surgery Unit Niguarda Cà Granda Hospital, Milan, ItalyNiguarda Cà Granda Hospital, Milan, Italy

MATERIALS and METHODSMATERIALS and METHODS

APRIL 2003- OCTOBER 2009APRIL 2003- OCTOBER 2009

29 PATIENTS29 PATIENTS

Ascending Aorta and Isolated Non-Coronary Sinus Replacement

Tricuspid valve:

16 Pts (13 Males, Mean Age 65 ± 11 y)

Bicuspid valve:

13 Pts (11 Males, Mean Age 52 ± 12 y)

Page 5: Luca Botta MD, Cardiac Surgery Unit Niguarda Cà Granda Hospital, Milan, Italy Partial aortic root remodeling with selective replacement of the non-coronary.

Luca Botta MD, Cardiac Surgery Unit Luca Botta MD, Cardiac Surgery Unit Niguarda Cà Granda Hospital, Milan, ItalyNiguarda Cà Granda Hospital, Milan, Italy

Ascending Aorta and Isolated Non-Coronary Sinus Replacement

Pre-operative FeaturesPre-operative Features

ETIOLOGYAORTIC ROOT ANEURYSM 13 pts RUPTURED ANEURYSM 0 ptsACUTE TYPE A DISSECTION 0 ptsPSEUDOANEURYSM 0 pts

13 pts

Asc Ao and NC Sinus Rep

16 pts

Asc Ao and NC Sinus Rep

ETIOLOGYAORTIC ROOT ANEURYSM 14 pts RUPTURED ANEURYSM 1 ptACUTE TYPE A DISSECTION 0 ptsPSEUDOANEURYSM 1 pts

REDO 3 pts REDO 4 pts

Mean Aortic Diameter 52.7 mm Mean Aortic Diameter 52.2 mm

Page 6: Luca Botta MD, Cardiac Surgery Unit Niguarda Cà Granda Hospital, Milan, Italy Partial aortic root remodeling with selective replacement of the non-coronary.

Luca Botta MD, Cardiac Surgery Unit Luca Botta MD, Cardiac Surgery Unit Niguarda Cà Granda Hospital, Milan, ItalyNiguarda Cà Granda Hospital, Milan, Italy

Intra-operative DataIntra-operative Data

Ascending Aorta and Isolated Non-Coronary Sinus Replacement

- CPB time: 147 + 60 min- Cross Clamp Time 118 + 53 min

ASSOCIATED PROCEDURESAVR 7 ptsLEAFLET PLASTY 3 ptsPROSTHETIC SUTURE 0 pts

- CPB time: 136 + 44 min- Cross Clamp Time 104 + 37 min

13 pts

Asc Ao and NC Sinus Rep

16 pts

Asc Ao and NC Sinus Rep

ASSOCIATED PROCEDURESAVR 5 ptsLEAFLET PLASTY 2 ptsPROSTHETIC SUTURE 2 pts

Page 7: Luca Botta MD, Cardiac Surgery Unit Niguarda Cà Granda Hospital, Milan, Italy Partial aortic root remodeling with selective replacement of the non-coronary.

Luca Botta MD, Cardiac Surgery Unit Luca Botta MD, Cardiac Surgery Unit Niguarda Cà Granda Hospital, Milan, ItalyNiguarda Cà Granda Hospital, Milan, Italy

IN-HOSPITAL OUTCOMESIN-HOSPITAL OUTCOMES

Ascending Aorta and Isolated Non-Coronary Sinus Replacement

Post-Operative stay: 7 Days (median)Post-Operative stay: 7 Days (median)

30 days MORTALITY: 0 pts30 days MORTALITY: 0 pts

30 days MORBIDITY30 days MORBIDITY- Stroke 1pt- Stroke 1pt- Renal/Respiratory Failure 1pt- Renal/Respiratory Failure 1pt

30 days MORBIDITY30 days MORBIDITY- Ventricular Fibrillation 1 pt- Ventricular Fibrillation 1 pt- Peripheral embolism 1 pt- Peripheral embolism 1 pt

Page 8: Luca Botta MD, Cardiac Surgery Unit Niguarda Cà Granda Hospital, Milan, Italy Partial aortic root remodeling with selective replacement of the non-coronary.

Luca Botta MD, Cardiac Surgery Unit Luca Botta MD, Cardiac Surgery Unit Niguarda Cà Granda Hospital, Milan, ItalyNiguarda Cà Granda Hospital, Milan, Italy

FOLLOW-UPFOLLOW-UP

LATE MORTALITY: 0 ptsLATE MORTALITY: 0 pts

Mean: 27.3 monthsMean: 27.3 months

Ascending Aorta and Isolated Non-Coronary Sinus Replacement

LATE MORBIDITY: 0 ptsLATE MORBIDITY: 0 pts

AORTIC DISSECTION: 0 ptsAORTIC DISSECTION: 0 pts

RE-OPERATIONS: 0 ptsRE-OPERATIONS: 0 pts

Mean: 32.3 monthsMean: 32.3 months

100% completed

Page 9: Luca Botta MD, Cardiac Surgery Unit Niguarda Cà Granda Hospital, Milan, Italy Partial aortic root remodeling with selective replacement of the non-coronary.

Luca Botta MD, Cardiac Surgery Unit Luca Botta MD, Cardiac Surgery Unit Niguarda Cà Granda Hospital, Milan, ItalyNiguarda Cà Granda Hospital, Milan, Italy

When dilatation of the aortic root is confined to theWhen dilatation of the aortic root is confined to theNon-coronary sinus of Valsalva, the selective replacementNon-coronary sinus of Valsalva, the selective replacementof this sinus may represent a good compromise, with of this sinus may represent a good compromise, with excellent early and midterm outcomes.excellent early and midterm outcomes.

In patients with a bicuspid aortic valve, risk of aortic In patients with a bicuspid aortic valve, risk of aortic related adverse events is rare and similar to that of related adverse events is rare and similar to that of patients with a tricuspid valve.patients with a tricuspid valve.

CONCLUSIONS

More patients and a longer follow-up is mandatory to More patients and a longer follow-up is mandatory to confirm these preliminary results.confirm these preliminary results.

Page 10: Luca Botta MD, Cardiac Surgery Unit Niguarda Cà Granda Hospital, Milan, Italy Partial aortic root remodeling with selective replacement of the non-coronary.

Luca Botta MD, Cardiac Surgery Unit Luca Botta MD, Cardiac Surgery Unit Niguarda Cà Granda Hospital, Milan, ItalyNiguarda Cà Granda Hospital, Milan, Italy

THANK YOU FOR YOUR ATTENTION


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