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PATOLOGI LIMPA

Kuliah PA

Fakultas Kedokteran

oleh

Noor Yazid AD

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KELAINAN KONGENITAL 

♦ASPLENIA6APLASIA

♦A)NORMAL LO)ULASI

♦

A77ESSOR8 SPLEEN  ditemuka# t.u. di 3auda &a#3reas

  "i'.'astr(s&"e#i3us

9u#'si : ide#tik d'. Lim&a ' as"i  Dam&ak#a : &d.tera&i s&"e#e3t(mi4 t;&uas

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SPLEENECTOMI

♦DE

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ETIOLOGISPLENOMEGALI

INFEKSI

GANGGUAN SIRKULASI

STORAGE DISEASE

NEOPLASIA

DISORDERD OF TE !LOOD

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AKUT SPLENI" TU#ORRada#' akut #(# s&esi9ik 

MAKROSKOPIK    MIKROSKOPIK

)erat : / 0,,$?,, 'r    Si#us ditutu&i darah 

Lu#ak@&u"&a seri#'$   Dia#tara#a tam&ak 

di99"ue#t.   "ek(sit PMN@makr(9a'

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ETIOLOGI SPLENITIS AKUT

PREDISPOSISI :

♠)AKTERIEMIA

  .e#d(@Di&teri@Dse#t.basi"er@P#eum(#ia

♠ET.TISSUE DISTR.OF 7EMI7AL

♠SEERE TOEMI7 DISEASE

  Stre&t(3(33us hem("ti3us 'r(u& A

♠P8EMIA

♠SEPTI7 EM)OLI

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SUBAKUT – CHRONIC

SPLENITIS♦ ETIOLOGI : .e#d(3arditis

♦ MAKROS. : Lim&a // → *,,, 'r.

  &erabaa# ke#a"@ =.abu$abu

  i#9ark

♦ MIKROS.: Pd.si#us B &u"&a tam&ak &adat

  (.k.&e#uh makr(9a'Bse" &"asma

"ek(sit PMN Hu'a ba#ak@

  mit(sis

  &a'(sit

se" Retik.e#d(te" hi&ertr(9i B kub(id

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  TBC LIMPA

7ARA MASUK : mi"ier 

UMUR : t.u.a#ak

SPLENOMEGALI

)ERAT : +,, 4 !,, 'r.

MAKROS B MIKROS

  TAMPAK TU)ERKEL

  di : $ se"uruh ka&su"

$ 3.ma"&i'i

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 T!" LI#PA #ILIAIR

Gambar makr(s :

Tam&ak 

mu"ti&e" 6 di9us

tuberke"

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SPLENITIS SPESIFIK 

T)7 SIFILIS SARKOIDOSIS

INF.MONO$ TIFOID )RU7ELLOSIS

 NUKLEOSISMALARIA KALA AAR ISTOPLASMO$

  SIS

S7ISTOSO$ ANTRAKOSIS AKTINOMIKO$

MIASIS SIS

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INFEKSI MONONUKLEOSIS

♦

ETIOLOGI : I#9eksi E)♦UMUR : *+ 4 *J th. &d.i'h 7"ass

♦KLINIK : miri& he&atitis &a#as@ he&at($

  s&"e#(me'a"i."im9ade#(&ati 'e#e$  ra"@#eri te#''(r(ka#

♦MAKROS : besar 12$02N@"u#ak@s&t.da'i#'@

  B hi&eremik.

♦MIKROS : &r("i9."im9(sit t&i36at&i3@

  i#9i"tr.trabe3.B 3a&s

→ mudah ru&tur 

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TYPHOID SPLENITIS

i Lim&a membesar 1+, 4 0+, 'r

iF(3a" #ekr(sis

i isti(sit ba#ak @ isi eritr(sit

i E#d(te" si#us a"ami hi&ertr(9i da# aktiv

mem9a'(sit eritr(sit da# se" debris.

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SPLENITIS LUETI7A

 LUES KONGENITAL s&"e#itis

  "im&a / @ 12N@ &erabaa# ke#a"

  Mikr(s : Har.ikat / @ i#9i"trasi "im9(sit Bse" &"asma

  LUES STADIUM III s&"e#(me'a"i

  meru&aka# 3(#'estive 3ha#'e akibatsir(sis "ues

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HYALIN PERISPLENITIS

♦AKADEMIK INTEREST

♦7LINI7AL DISFUNGTION : $ #e'ati9

♦UNSUR : $ hia"i#

  $ k("a'e# teba"

  $ 9ibr(sis

♦ETIOLOGI : → mu#'ki# kr#.:

$ &eris&"e#itis

  $ asites ' "ama

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  8ALIN PERISPLENITIS

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SPLENITIS padaMALARIA♦STAD AKUT : membesar da# "u#ak 

♦MIKROS : Parasit ditemuka# &ada :

  &u"&a bebas   eritr(sit

  se" retiku"um

  e#d(te" &e#uh isi &arasit B  &i'me#

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SPLENITIS $ada #ALARIA 

 KRONIK  : "im&a ///*,,,$?,,, 'r.

  K(#siste#si : ke#a"

  Ka&su" : me#eba" B me"ekat  MIKROS : >ar.ikat tumbuh ///

  ka"au sembuh .

  → "im&a me#'erut 6 3i3atri2 Bdisertai timbu#a# &i'me#

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ACUT VASCULAR DISEASE

♦PADA : $ &r(ses &e#3er#aa# mi"d $

hi&eremi

  $ T(2emia

$ I#9eksi akut

♦MAKROS : Lim&a / %1+, 'r.@"u#ak 

  Q =ar#a merah

♦MIKROS : sembab &d si#us (k.er

  → 7.ma"&i'i me"ebar

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CHRONIC VASCULAR DISEASE( CHRONIC VENOUS CONGESTION )

♦ETIOLOGI :  I#tra he&ati3 (bstru3ti(#

   Obstruksi v.&(rta6v."ie#a"is

   7(#'estiv ve#(us sstemi3  de3(m&.ka#a# @ 7P

   E2tra he&ati3 (bstru3ti(#

  tr(mb(sis v.&(rta s&(#ta# 6 (.k.sebab "ai#

♦)erat *,,, 'r. %on&esti'e

s$leno(e&ali

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INFARK LIMPA

♦ETIOLOGI : Pe#umbata# : $ emb("i

  $ tr(mb(sis

♦

MAKROS : =.ke$&utiha#  tertutu& 9ibri# di ka&su"

♦ARTI KLINIK : Pe#ti#' utk &drt tua d'#

  Pe#.>a#tu#'  8' tiba #eri di dada kiri

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#AKROS)INFRAK LIEN

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  INFARK LIMPA tr(mb(s

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  HYPERSPLENISME

♦S8NDROME : 7(#'esti

  Leuk(&e#i

  A#emia♦ADA 1 TIPE : &rimer B seku#der

♦Seku#der (.k. "ek(&e#i@ LMN @ I#9eksi@

  Fe"ts si#dr(m.♦ (polyar!r""#$ %&'&r$ a&)"a $ l&*op&"$#pl&o)&+al",

♦)ANTI S8NDR.: 'a#''.hem("itik &rimer@

  diikuti ter"ibat#a "im&a

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RUPTURA LIENALIS

♦ KEKERASAN

♦ KLL

♦ PERKELAIAN

♦ >ATU   ♦ SPONTAN

♦ INF.MONONUKL.

♦ MALARIA

♦ T8POID♦ LEUKEMIA

♦ AKUT SPLENITIS

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NEOPLASMA LIENALIS 

♦ >INAK : haema#'i(ma B "m&ha#'i(ma

♦GANAS :

• Primer : LN B L Hara#'

  • Seku#der : su"it

  (.k.*. Tidak subur 

  1. Dd.arteri("e teba"

  • Ka"au ada : $ &ertumbuha# retr('ade

  $ &ertumbuha# di ka&su"