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M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004 Health and the Life Event ´Death of Spouse´ in Elderly Women Maren Dreier, Heike Koch-Gießelmann, Siegfried Geyer Hannover Medical School, Hannover Hannover Medical School, Hannover Department of General Medicine and Medical Sociology
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Page 1: M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004 Health and the Life Event ´Death of Spouse´ in Elderly Women Maren Dreier, Heike Koch-Gießelmann,

M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004

Health and the Life Event ´Death of Spouse´ in Elderly Women

Maren Dreier, Heike Koch-Gießelmann, Siegfried Geyer

Hannover Medical School, HannoverHannover Medical School, Hannover

Department of General Medicine and Medical Sociology

Page 2: M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004 Health and the Life Event ´Death of Spouse´ in Elderly Women Maren Dreier, Heike Koch-Gießelmann,

M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004

IntroductionTwo-factor-model (Geyer,1999, based on Brown & Harris, 1978):

The association between life events and the development of illness

Changes in health status

Provoking agents

Vulnerability factors

Life events

Chronic difficulties

biological

mental/social vulnerability

Subject

environmental

Loss

Threat

Personal factors

Early loss events

Mat. ressources

Social support

aquired

congenital

Page 3: M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004 Health and the Life Event ´Death of Spouse´ in Elderly Women Maren Dreier, Heike Koch-Gießelmann,

M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004

AimTwo-factor-model (Geyer,1999, based on Brown & Harris, 1978):

The association between life events and the development of illness

Changes in health status

Provoking agents

Vulnerability factors

Life events

Chronic difficulties

biological

mental/social vulnerability

Subject

environmental

Loss

Threat

Personal factors

Early loss events

Mat. ressources

Social support

aquired

congenital

Page 4: M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004 Health and the Life Event ´Death of Spouse´ in Elderly Women Maren Dreier, Heike Koch-Gießelmann,

M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004

AimTwo-factor-model (Geyer,1999, based on Brown & Harris, 1978):

The association between life events and the development of illness

Changes in health status

Provoking agents

Vulnerability factors

Life events

Chronic difficulties

biological

mental/social vulnerability

Subject

environmental

Loss

Threat

Personal factors

Early loss events

Mat. ressources

Social support

acquired

congenital

Death of spouse

Page 5: M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004 Health and the Life Event ´Death of Spouse´ in Elderly Women Maren Dreier, Heike Koch-Gießelmann,

M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004

AimTwo-factor-model (Geyer,1999, based on Brown & Harris, 1978):

The association between life events and the development of illness

Changes in health status

Provoking agents

Vulnerability factors

Life events

Chronic difficulties

biological

mental/social vulnerability

Subject

environmental

Loss

Threat

Personal factors

Early loss events

Mat. ressources

Social support

aquired

congenital

Death of spouse

Coping dimension:• hope/optimism• self-blame

Page 6: M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004 Health and the Life Event ´Death of Spouse´ in Elderly Women Maren Dreier, Heike Koch-Gießelmann,

M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004

AimTwo-factor-model (Geyer,1999, based on Brown & Harris, 1978):

The association between life events and the development of illness

Changes in health status

Provoking agents

Vulnerability factors

Life events

Chronic difficulties

biological

mental/social vulnerability

Subject

environmental

Loss

Threat

Personal factors

Early loss events

Mat. ressources

Social support

aquired

congenital

Death of spouse

Coping dimension:• hope/optimism• self-blame

Mental health

Page 7: M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004 Health and the Life Event ´Death of Spouse´ in Elderly Women Maren Dreier, Heike Koch-Gießelmann,

M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004

Design

Case-control-study 3/02-3/04:• cases: bereaved women, age >= 70 years,

bereaved for 2-5 months controls: married women, age >= 70 years

• interviews at home: standardized instruments, a qualitative semi-structured interview (tape-recorded); medical questionnaire completed by the family doctor

• t0 : cases/controls n= 45/83

t1 : cases/controls n= 44/78

• loss to follow-up: 4,7%

Page 8: M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004 Health and the Life Event ´Death of Spouse´ in Elderly Women Maren Dreier, Heike Koch-Gießelmann,

M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004

Measures

Outcome: Mental health• Health-related Quality of Life: SF-12, mental component

summary (Bullinger M, Kirchberger I, 1998) • Screening for Depression: Geriatric Depression Scale GDS-15

(Yesavage JA et al, 1983)

• Antidepressive medication: prescription of antidepressants by general practioners

Coping:• Bedford College Coping Inventory COPI (Bifulco A, Brown GW, 1996) • Life Events and Difficulties Schedule LEDS (Brown GW, Harris T,

1978)

Page 9: M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004 Health and the Life Event ´Death of Spouse´ in Elderly Women Maren Dreier, Heike Koch-Gießelmann,

M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004

Study population

Variable Parameter Cases ControlsAge ofparticipants(years)

nM

SD

4575,8

4,7

8375,5

4,4

Age ofspouse(years)

nM

SD

4281,3

6,4

8377,3

6,2

Duration ofpartnership(years)

nM

SD

4445,512,0

8248,9

8,7

M: Mean SD: Standard deviation

Page 10: M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004 Health and the Life Event ´Death of Spouse´ in Elderly Women Maren Dreier, Heike Koch-Gießelmann,

M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004

4478 4583N =

Mental quality of life

casescontrols

SF

-12

, m

en

tal c

om

po

ne

nt

sum

ma

ry s

core

80

70

60

50

40

30

20

10

t 0

t 1

Results I: Mental health

Mean of German standard sample

> 70 years

t 0: p<0,01 t 1: p=0,05(Mann-Withney-U-Test)

Page 11: M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004 Health and the Life Event ´Death of Spouse´ in Elderly Women Maren Dreier, Heike Koch-Gießelmann,

M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004

4478 4583N =

Mental quality of life

casescontrols

SF

-12

, m

en

tal c

om

po

ne

nt

sum

ma

ry s

core

80

70

60

50

40

30

20

10

t 0

t 1

Results I: Mental health

Mean of German standard sample

> 70 years

t 0: p<0,01 t 1: p=0,05(Mann-Withney-U-Test)

Page 12: M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004 Health and the Life Event ´Death of Spouse´ in Elderly Women Maren Dreier, Heike Koch-Gießelmann,

M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004

1133 1233N =

Mental quality of life, modified by hope/optimism

low degreehigh degreeS

F-1

2,

me

nta

l co

mp

on

en

t su

mm

ary

sco

re

80

70

60

50

40

30

20

10

t 0

t 1

4478 4583N =

Mental quality of life

casescontrols

SF

-12

, m

en

tal c

om

po

ne

nt

sum

ma

ry s

core

80

70

60

50

40

30

20

10

t 0

t 1

Results I: Mental health, modified by hope/optimism

Mean of German standard sample

> 70 years

Mean of German standard sample

> 70 years

t 0: p<0,01 t 1: p=0,05(Mann-Withney-U-Test)

t 0: p=0,08 t 1: p<0,05(Mann-Withney-U-Test)

Page 13: M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004 Health and the Life Event ´Death of Spouse´ in Elderly Women Maren Dreier, Heike Koch-Gießelmann,

M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004

3212 3312N =

Mental quality of life, modified by self-blame

low degreehigh degreeS

F-1

2,

me

nta

l co

mp

on

en

t su

mm

ary

sco

re

80

70

60

50

40

30

20

10

t 0

t 1

4478 4583N =

Mental quality of life

casescontrols

SF

-12

, m

en

tal c

om

po

ne

nt

sum

ma

ry s

core

80

70

60

50

40

30

20

10

t 0

t 1

Results I: Mental health, modified by self-blame

Mean of German standard sample

> 70 years

Mean of German standard sample

> 70 years

t 0: p<0,01 t 1: p=0,05(Mann-Withney-U-Test)

t 0: p<0,01 t 1: p<0,05(Mann-Withney-U-Test)

Page 14: M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004 Health and the Life Event ´Death of Spouse´ in Elderly Women Maren Dreier, Heike Koch-Gießelmann,

M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004

4478 4483N =

Screening for depression

casescontrols

Ge

ria

tric

de

pre

ssio

n s

cale

, sc

ore

15

14

13

12

11

10

9

8

7

6

5

4

3

2

10

t 0

t 1

Results II: Symptoms of depression

t 0: p<0,01 t 1: n.s.(Mann-Withney-U-Test)

Page 15: M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004 Health and the Life Event ´Death of Spouse´ in Elderly Women Maren Dreier, Heike Koch-Gießelmann,

M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004

4478 4483N =

Screening for depression

casescontrols

Ge

ria

tric

de

pre

ssio

n s

cale

, sc

ore

15

14

13

12

11

10

9

8

7

6

5

4

3

2

10

t 0

t 1

Results II: Symptoms of depression

t 0: p<0,01 t 1: n.s.(Mann-Withney-U-Test)

Page 16: M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004 Health and the Life Event ´Death of Spouse´ in Elderly Women Maren Dreier, Heike Koch-Gießelmann,

M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004

1133 1232N =

Screening for depression, modif. by hope/optimism

low degreehigh degreeG

eri

atr

ic d

ep

ress

ion

sca

le,

sco

re

15

14

13

12

11

10

9

8

7

6

5

4

3

2

10

t 0

t 1

4478 4483N =

Screening for depression

casescontrols

Ge

ria

tric

de

pre

ssio

n s

cale

, sc

ore

15

14

13

12

11

10

9

8

7

6

5

4

3

2

10

t 0

t 1

Results II: Symptoms of depression, modified by hope/optimism

t 0: p<0,01 t 1: n.s.(Mann-Withney-U-Test)

t 0: n.s. t 1: n.s.(Mann-Withney-U-Test)

Page 17: M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004 Health and the Life Event ´Death of Spouse´ in Elderly Women Maren Dreier, Heike Koch-Gießelmann,

M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004

3212 3212N =

Screening for depression, modified by self-blame

low degreehigh degreeG

eri

atr

ic d

ep

ress

ion

sca

le,

sco

re

15

14

13

12

11

10

9

8

7

6

5

4

3

2

10

t 0

t 1

4478 4483N =

Screening for depression

casescontrols

Ge

ria

tric

de

pre

ssio

n s

cale

, sc

ore

15

14

13

12

11

10

9

8

7

6

5

4

3

2

10

t 0

t 1

Results II: Symptoms of depression, modified by self-blame

t 0: p<0,01 t 1: n.s.(Mann-Withney-U-Test)

t 0: n.s. t 1: p=0,06(Mann-Withney-U-Test)

Page 18: M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004 Health and the Life Event ´Death of Spouse´ in Elderly Women Maren Dreier, Heike Koch-Gießelmann,

M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004

Results III: Antidepressants

Prescription of Antidepressants

CasesControls

Pe

rce

nta

ge

s

50

40

30

20

10

0

1. quarter *

2. quarter *

3. quarter *

4. quarter *

9

3

14

3

20

4

18

4

* In controls quarterly periods after the first interview, in cases quarterly periods after death of spouse.

1.-3. quarter: p<0,05 4. quarter: n.s.(Mann-Withney-U-Test)

Page 19: M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004 Health and the Life Event ´Death of Spouse´ in Elderly Women Maren Dreier, Heike Koch-Gießelmann,

M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004

Results III: Antidepressants

Prescription of Antidepressants

CasesControls

Pe

rce

nta

ge

s

50

40

30

20

10

0

1. quarter *

2. quarter *

3. quarter *

4. quarter *

9

3

14

3

20

4

18

4

* In controls quarterly periods after the first interview, in cases quarterly periods after death of spouse.

1.-3. quarter: p<0,05 4. quarter: n.s.(Mann-Withney-U-Test)

Page 20: M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004 Health and the Life Event ´Death of Spouse´ in Elderly Women Maren Dreier, Heike Koch-Gießelmann,

M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004

Results III: Antidepressants, modified by hope/optimism

Prescription of Antidepressants

CasesControls

Pe

rce

nta

ge

s

50

40

30

20

10

0

1. quarter *

2. quarter *

3. quarter *

4. quarter *

9

3

14

3

20

4

18

4

Prescr.of Antidepressants, modif. by hope/optimism

low degree of hopehigh degree of hopeP

erc

en

tag

es

50

40

30

20

10

0

1. quarter *

2. quarter *

3. quarter *

4. quarter *

99

18

12

27

18

36

12

* In controls quarterly periods after the first interview, in cases quarterly periods after death of spouse.

1.-3. quarter: p<0,05 4. quarter: n.s.(Mann-Withney-U-Test)

1.-4. quarter: n.s. (Mann-Withney-U-Test)

Page 21: M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004 Health and the Life Event ´Death of Spouse´ in Elderly Women Maren Dreier, Heike Koch-Gießelmann,

M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004

Presc. of Antidepressants, modified by self-blame

low degreehigh degreeP

erc

en

tag

e

50

40

30

20

10

0

1. quarter *

2. quarter *

3. quarter *

4. quarter *

98 9

25

15

33

15

25

Results III: Antidepressants, modified by self-blame

Prescription of Antidepressants

CasesControls

Pe

rce

nta

ge

s

50

40

30

20

10

0

1. quarter *

2. quarter *

3. quarter *

4. quarter *

9

3

14

3

20

4

18

4

* In controls quarterly periods after the first interview, in cases quarterly periods after death of spouse.

1.-3. quarter: p<0,05 4. quarter: n.s.(Mann-Withney-U-Test)

1.-4. quarter: n.s. (Mann-Withney-U-Test)

Page 22: M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004 Health and the Life Event ´Death of Spouse´ in Elderly Women Maren Dreier, Heike Koch-Gießelmann,

M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004

Summary

• Loss of spouse in elderly women is followed by impairment of mental health

• One year after loss improvements in mental health have occurred

• Hope/optimism and self-blame may moderate the degree of mental impairment

Page 23: M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004 Health and the Life Event ´Death of Spouse´ in Elderly Women Maren Dreier, Heike Koch-Gießelmann,

M. Dreier * ESHMS - SISS International Joint Congress * Bologna 2004

Further directions

• Long-term follow-up: morbidity and mortality

• Examination of the role of social support


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