MacromoleculesProteins

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ProteinsProteins are used for:

Amino acids.

Amino Acids

Amino Acids in Aqueous SolutionsWhat are the acid / base properties of the amino acid

functional groups?

Amino Acids

Essential vs. Non-essential Amino Acids

non-essential amino acids

essential amino acids

Peptides

amide bond

Protein Organization

Four layers of protein organization:1. primary (1°) structure

2. secondary (2°) structure

3. tertiary (3°) structure

4. quaternary (4°) structure

Primary (1°) Structure

Secondary (2°) Structure

Tertiary (3°) StructureThis provides the final 3-D protein structure.

Four major bond types between R groups:1. H-bonding

2. ionic bonding

3. hydrophobic interactions

4. covalent bond (disulfide bridge)

Secondary (2°) and Tertiary (3°) Structure

Tertiary (3°) Structure

Quaternary (4°) Structure

General Protein Shapesglobular fibrous

Protein PropertiesDenature.

Vs.

Renaturation.

Protein Folding

Protein Folding

Protein Organization

Protein Organization Video