Maintain quality of lifeMaintain quality of lifethroughthrough

Modern Chinese Herbal Modern Chinese Herbal MedicineMedicine

Speaker : Dr.Joseph H.C.Lui

Ph D. Pharmacognosy

University of Minnesota, USA

Registered Chinese Medicine

Practitioner, Hong Kong.

ContentContent

Unlock the mystery of Chinese herbal medicine

Why Chinese herbal medicine has to be modernized?

Maintain quality of life

Unlock the Mystery of Unlock the Mystery of Chinese Herbal MedicineChinese Herbal Medicine

General Concept

Chinese Medicine

Minimum side effects

Cure (treating theunderlying illness)

Natural

Compound Formulation

Western Drug

Harmful side effects

Control (alleviating the symptoms)

Chemical Compound

Single Component Formulation

Types of Chinese Medicine

5776 items (Pharmacopoeia of Chinese

Herbal Medicine)

Animal, Plant, Microorganism, Mineral

All natural

Processed and Refined into Chinese

Medicine

Modern Chinese herbal medicine

Types of Western Drug

1300 items (PDR)

Animal, Plant, Microorganism, Mineral,

Synthetic, Biotechnology

> 50% natural

Extraction and purification

Chinese vs Western DrugChinese vs Western Drug

Compound Formulation

Single component Formulation

Make Up of Compound FormulationMake Up of Compound Formulation

Know-how

Art instead of Science

Experience and Clinical Studies

337 known formulae

Principal herb — Main ingredient for the cure

Assistant herb — Strengthens the effect of the

principal herb

Adjuvant herb — Reduces or eliminates the

toxicity and other side effects

of the principal and the

assistant herbs

Guiding herb — Directs, Coordinates and/or

mediates the effects of the

principal and assistant herbs

to the affected site

Bazhen Tang Bazhen Tang (Reinforcing the vital energy & (Reinforcing the vital energy &

nourishing the blood)nourishing the blood)

Radix Codonopsis

Pilosulae 10g

Rhizoma Atractylodis

Macrocephalae 10g

Poria 10g

Radix Glycyrrhizae 5g

Rhizoma Ligustici

Chuanxiong 10g

Radix Angelicae Sinensis 10g

Radix Paeoniae Alba 10g

Rhizoma Rehmanniae

Preparatae 10g

A typical compound formula embodied Principle, Assistant, Adjuvant & Guiding herbs

Compound Formulation of Western Drug – Aids Treatment

Dr. David Ho is one of the well- known scientists in Aids research

Develop Cocktail Treatment

What is Cocktail TreatmentWhat is Cocktail Treatment

Mixing three to four kinds of antiviral drugs

Compound formulation

RITONAVIR + AZT + 3TC

INDINAVIR + AZT + 3TC

Why Cocktail Treatment is better ?Why Cocktail Treatment is better ?

Virus being attacked in various mode of actions

Wide spectrum

Control but not cure

Adjuvant DrugAdjuvant Drug Reduce side effects

Bufferin

Aspirin – moderate pain and reduce fever

Sodium Bicarbonate – neutralize stomach acid

Synergistic

Guiding DrugGuiding Drug

Monoclonal Antibody

Targeting Drug

Magic Bullet

Touch-and-go

The Advantages of Compound The Advantages of Compound FormulationFormulation

Multi specificity vs high specificity

Wide spectrum

Synergistic

Multi channels

Same functions but with different mode of actions

Why Chinese Herbal Medicine Why Chinese Herbal Medicine has to be modernized ?has to be modernized ?

Principles of Modern Principles of Modern Chinese Herbal Medicine Chinese Herbal Medicine

Safety

Efficacy

Stability & Consistency

Raw Materials SafetyRaw Materials Safety

Heavy metals

Microbes contamination

Herbacide & Insecticide Residues

Products SafetyProducts Safety Acute Toxicity Study Subacute Toxicity Study Chronic Toxicity Study Reproductive Toxicology Drug Dependence Antigenicity Study Mutagenicity Study Carcinogenicity Study Local Irritation Study

Good Laboratory Practices

EfficacyEfficacy In-vitro Study In-vivo Study

Animal study Clinical study

Clinical Trial Unbiased Independent Properly designed

Good Clinical Practices

Stability & ConsistencyStability & Consistency

Whole Plants Authentication Tissue Analysis Chemical Composition Analysis DNA Analysis

Manufacturing of Chinese Medicines Quality Control Quality Assurance

Good Manufacturing Practices

No. 1

To prove the safety of herbal medicines

To provide strong scientific proof of the effectiveness of the herbal medicines through a well designed clinical trial

To strengthen batch to batch consistency which means quality assurance of the herbal medicines

The genuine Modern Chinese Herbal Medicine

Maintain quality of lifeMaintain quality of life

Five Principle Elements for longevity

Blood pressure lower than 120/80

Total blood cholesterol lower than 200mg/dl

Normal blood sugar level

Free from smoking

Never have stroke

According to the Journal of the American Medical Association 1999; 282: 2012 – 2018

*

People who meet the five principle elements for longevity ：

Average life-span will longer than normal person at least 91/2years

Youngster < 9%

Middle-Age groups < 5%

Major reasons for agingMajor reasons for aging Inborn factor (40%)

Heredity

Acquired factor (60%)

Diseased factor (cardiac, liver, spleen,

lung, kidney and cancer diseases)

Social factor (Science & culture, Substances & life

style)

Environmental factor (Environmental pollution, viral

or bacterial infection)

Other factor (Exercise, Eating habits, Mood, Health

supplements)

Proper Lifestyle for Quality of LifeProper Lifestyle for Quality of Life

Proper exercise

Drink minimum 8 glasses of water everyday

Balanced diet

Eat lightly

Think positive

Proper health supplements

Good Health & Happy LifeGood Health & Happy Life

Thank you ！