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Nanotechnology Report 2006
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Page 1: M&C Biotech Report 06 - Marks & Clerks/… · We looked at bionanotechnology in our first Biotechnology Report in 2005. Our Nanotechnology Report 2006 expands on this field to cover

NanotechnologyReport 2006

Page 2: M&C Biotech Report 06 - Marks & Clerks/… · We looked at bionanotechnology in our first Biotechnology Report in 2005. Our Nanotechnology Report 2006 expands on this field to cover

Contents

Foreword . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . page 1

Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . page 2

Nanoelectronics. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . page 3

Background

The market

The patent landscape

The key players

The future

Nanotechnology in the health and personal care sectors. . . . . . . . . . . . . . . . . . . . . . page 9

Background

The market

The patent landscape

The geographical landscape

The key players

The future

Nanoenergy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . page 13

The market

The patent landscape

The key players

The future

Conclusions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . page 18

Marks & Clerk contacts . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . page 19

CONTENTS

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There can be no doubt about the importance of nanotechnology across many areas of scientific

development. It is not only increasingly recognised as a key enabling technology for many

industry sectors, through the development of novel nanomaterials, but is also poised to provide

many societal advantages. Nanotechnology is leading to many advances in the field of medicine,

such as new techniques in organ regeneration, faster and earlier diagnosis of disease, and in

better targeting of drugs. Nanotechnology also offers environmental benefits, being less

resource intensive (‘more for less’), as well as providing new ways of harnessing renewable

energy and enabling more efficient and effective use of existing techniques.

This report on nanotechnology patenting by Marks & Clerk offers an insight into three critical and exciting areas

where nanotechnology is having a major impact – namely nanoelectronics, nanotechnology in the health and personal care

sectors, and nanoenergy.

These areas mirror the themes of the recent EU-funded NanoRoadMap project (see http://www.nanoroadmap.it/) which provides

useful reading, and helps to put the patent landscape into context.

Trends in nanotechnology patenting are different from any previous patent activity in any other sector to date. It is one area

where, over the last few years, commercially applicable innovations have emerged in quantity from the academic base, often

leading to major technological breakthroughs, applicable in more than one industry sector. So even more reason to keep a watchful

eye on the patent landscape, as one patent may have many important ramifications.

For this very reason, the Marks & Clerk report makes for unmissable reading, while also providing a warning to industry as a whole.

It will come as no surprise to anyone that the levels of innovation and activity in nanotechnology have dramatically accelerated in

the last five years. However, the report provides firm evidence for what we have known for a while: that significant European

investment into nanotechnology research has not been matched by a rush to patent, and therefore benefit commercially, from this

scientific endeavour. In contrast, companies and publicly-funded institutions in the Far East and the US have put their commercial

stake in the ground through IP protection. European organisations lag behind in all three areas examined in the report and greater

co-ordination within Europe is needed to reverse this trend.

In essence, the Marks & Clerk Nanotechnology Report 2006 is timely and useful. At last the nanotechnology community

has valuable data about nanotechnology innovations, measured by patents, as well as sector activity, on which to build a

future strategy.

Ottilia SaxlFounder and CEO, The Institute of Nanotechnology

FOREWORD

page 1

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Following on from our two recent Biotechnology Reports published in 2005 and 2006, we are pleased to present the first Marks

& Clerk report investigating patent filing trends in nanotechnology.

Nanotechnology is a notoriously hard subject to search because many of the cutting edge developments in the field extend across

more than one technical discipline. Also, the definition of the term “nanotechnology” has changed over the last 20 years. Initially,

nanotechnology strictly referred to structures with dimensions or manufacturing tolerances of 10 nm or less. Over the years, the

term has gradually been extended to cover structures with dimensions or tolerances of 100 nm and sometimes slightly larger. Our

search strategy, which will be explained for each section, was designed to try to isolate genuine trends in nanotechnology patent

filings as opposed to the changing definition of nanotechnology.

The three focus areas of the report are: nanoelectronics, nanotechnology in the health and personal care sectors, and nanoenergy.

We chose to cover these three areas as they are of current interest but also mirror the three key areas identified in the European

NanoRoadMap (NRM)1. This will allow us to revisit these areas over the coming years to see if the NRM makes a difference to the

European picture.

Nanoelectronics is the most active patenting field at the moment and has been for many years. This is hardly surprising as the

trend in electronics has always been to make things smaller. Many of the developments in other nanotechnology fields, such as

quantum dot bio-sensors, are built on techniques first developed in the electronics industry.

We looked at bionanotechnology in our first Biotechnology Report in 2005. Our Nanotechnology Report 2006 expands on this

field to cover nanotechnology applications in the health and personal care sectors. Our findings include cosmeceuticals and

neutraceuticals as both areas have embraced developments in nanotechnology and potentially many of the inventions in these

areas could be applied to pharmaceuticals. Nanotechnology gives us the situation whereby a cosmetics company may hold a

patent which is of use to a pharmaceutical company.

Finally, we turn to nanoenergy which was ranked number 1 in a report by the Canadian Joint Centre for Bioethics as being the most

promising area for nanotechnology developments2 . For nanoenergy we concentrate on energy storage and production using

mainly electrical methods. We have not covered fuel additives which rely on nanotechnology.

This report was compiled using, in part, patent searching performed on our behalf by CPA analytics.

page 2

INTRODUCTION

1 The European NanoRoadMap is a project funded by the EuropeanCommission to provide a 10 year forecast of the future of nanotechnologywith a view to directing resources and funding to the areas identified by the project.

2 http://news.bbc.co.uk/1/hi/sci/tech/4421867.stm

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NANOELECTRONICS

page 3

Figure 1: Earliest Priority filings for nanoelectronics

Source: Computer Patent Annuities Limited Partnership/Marks & Clerk ©2006

"The field of nanoelectronics is moving extremely

rapidly and understanding the patent landscape is very

important to companies in this field. This report gives

a valuable and timely assessment that should be very

useful to anyone with an interest in nanoelectronics."

Dr. Mike Pitkethly, CEO of Cenamps and co-founder/former

commercial director of QinetiQ Nanomaterials Ltd

BackgroundNanoelectronics is the application of nanotechnology to

electronic devices and processes for manufacturing such

devices. Reducing the scale of electronic devices to the nano

level provides substantial improvements in device speed

and performance, as well as manufacturing capabilities.

Blue-sky research into nanoelectronics holds the promise

of fundamentally new devices, with the potential to

revolutionise the electronics industry in the way that the

invention of the transistor did in the late 1960s.

Of all the areas of nanotechnology covered in this report,

nanoelectronics is the most mature, with significant academic

research being conducted in the mid to late eighties. In recent

years, however, the technology has moved from the lab and

started to shows signs of entering mainstream markets.

Currently, the nanoelectronics applications that are

closest to the market include semiconductor equipment and

manufacture, flat panel displays, integrated circuit

manufacture, data storage and sensors.

Initial research and development in nanoelectronics focused

on single devices. However, the US National Science

Foundation recently reported that much of the work now

being done is moving towards nanostructures and

nanosystems, such as nanoelectromechanical systems

(NEMS), nanobiodevices, transistors, actuators, molecular

motors, plasmonics, nanoscale fluidics, laser emitting devices,

and adaptive nanosensors. Since even this small group of

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devices could be incorporated in countless products, it is likely

that the next development phase in nanoelectronics will

yield significant commercial gains.

The marketWorldwide investment in nanotechnology research and

development, as reported by national government

organisations and the European Union, has increased

approximately nine times in the period 1997-2005, from

$432 million to $4.1 billion. This represents an average

annual growth rate of 32%. It is one of the fastest growing

areas of R&D, and is benefiting from almost unprecedented

levels of government funding on a global scale.

In 2000, US President Bill Clinton announced the formation of

the US National Nanotechnology Initiative (NNI) to support

long-term nanoscale research and development. In 2003, the

US Government allocated $3.7 billion over a four year period

to nanotechnology research and development. Current

estimates from venture capitalists indicate that the global

government spend for 2006 will be around $6 billion.

According to figures published by the Nanosciences and

Nanotechnology Unit of the European Commission, funding in

2004 for nanotechnology R&D in Europe exceeded $2.4

billion, with $1.7 billion being from the public purse and $0.7

billion being private. The same report estimated that the US

spent $3.6 billion, comprising of $1.5 billion public and $2.1

billion private. In Japan total funding was around $2.8 billion

with $0.9 billion public and $1.9 billion private.

As nanotechnology is still generally in the research

phase, the long-term economic impact is difficult to

quantify. However, the US National Science Foundation

has estimated that the global product and services market

for nanotechnology will be $1 trillion by 2015, with

nanoelectronics accounting for about $300 billion. According

to the Semiconductor Industry Association (SIA), this

may be a conservative estimate and the market for

page 4

Figure 2: Earliest priority filings and grants per country in the field of nanoelectronics

Source: Computer Patent Annuities Limited Partnership/Marks & Clerk ©2006

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page 5

nanoelectronics will exceed $300 billion by 2008. Even if

these estimates are over optimistic, it is clear that the global

market for nanoelectronics could provide huge commercial

opportunities.

The patent landscapeAlthough one of the first patent applications in this area was

filed by Hitachi in 1988, 80% of all patent filing activity has

occurred since 1999. This is illustrated in Figure 1, which

shows a steep increase in the number of priority patent

applications3 filed from 1999 to 20034, an average growth

rate of 28% per annum. However, we predict that the trend of

increasingly more applications being filed is likely to continue

in coming years.

The countries in which patent applications were first filed are

shown in Figure 2, for the period 2000-2005. This illustrates

that about 37% of applications were filed first in the US, 30%

were filed first in Japan and 13% filed first in Europe. Since

most applications are filed first in the applicant’s country of

origin, this data reflects the significant amount of research

and development being done in the US and Japan.

Figure 3: Patent applications over time for nanoelectronics

Source: Computer Patent Annuities Limited Partnership/Marks & Clerk ©2006

Figure 4: Patent grants over time for nanoelectronics

Source: Computer Patent Annuities Limited Partnership/Marks & Clerk ©2006

3 Our strategy for searching in this field has relied on a combination ofkeywords and classifications awarded by the patent offices. The “nano” prefixwas used during the search, but care was taken to ensure that logic operatorswere used during keyword searching to ensure that the search was asaccurate as possible. Also, other terms used to demote nanoelectronics such

as “quantum dot” etc were implemented. Where keyword searching was used,whole patent documents were searched and not just the abstract and claims.

4 Full year data is only available up until the end of 2003, because of the 18month delay between filing and publication of a patent application.

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page 6

Having said this, some large companies have a strategy of

filing first in the US, regardless of where they are based, and

so this may lead to an over estimate of the filing activity of

US based applicants. However, our raw data indicates that

this would not have a significant impact on the figures. In

contrast, the number of patent applications being filed first in

Europe is surprisingly low considering the high levels of

public and private funding.

Figure 3 shows the number of patent applications filed over

the period 2000-2003. This illustrates in more detail the sharp

increase in filing rates over the past few years. As would be

expected, the number of patents granted over the period

2000-2005 has also increased significantly, as can be seen

from Figure 4. Interestingly, the data for 2005 suggests that

whilst the number of patents granted in this field outside the

US continued to increase, the number of US grants was slightly

less than for 2004. It is not clear why this would be the case,

although the current backlog in the US Patent Office is causing

some delays, which would have an impact on the number of

patents granted. According to US Patent Office statistics,

across the board 12% fewer US patents were granted in 2005

than in 2004. Hence, although there is a slight decrease in US

grants in the nanoelectronics field, this is significantly less

than the overall drop for 2005.

The key playersFigure 5 shows the top thirty patent applicants in the

nanoelectronics field over the period 2000-2005 and

based on a count of the number of patent families filed. Of these,

18 are based in the Far East, 10 are based in the US and 2 are

based in Europe. Overall, Fujitsu has filed the most, with 62

nanoelectronics patent families. Samsung, incorporating data for

the two companies Samsung Electronics and Samsung SDI, is a

close second with 35 patent families in the name of Samsung

Electronics and 21 families in the name of Samsung SDI.

Whilst Fujitsu has filed most families, Figure 6 shows that in

the past few years, the most active players are Samsung,

Hewlett Packard, Hitachi, Japan Science and Technology

Agency/Corporation, Infineon Technologies and Philips. The

increased activity of players based in the Far East reflects a

general shift in levels of patent filing activity from the

traditionally IP savvy US corporates to, in particular, Japanese

companies. In recent years, this shift has been seen across the

board for all patent applications. For example, in 2005

six of the top ten filers of US patent applications were

Japanese companies.

In terms of filing strategies, all of the top thirty players file in

the US, Japan and Europe. Beyond these core regions tactics

seem to vary. For example, Samsung and the Korean

Advanced Institute of Science & Technology file in Korea, as

may be expected, since that is their home territory. However,

none of the other top thirty file in Korea. In China, only

Samsung, Infineon, Philips and IBM have filed patent

applications, and in Australia, only Philips, IBM, Agilent,

Nantero and the University of California have filed.

Most of the top ten filers in nanoelectronics are large corporate

players, four based in Japan, two based in the US and two in

Europe. The exceptions to this are the Japan Science and

Technology (JST) Agency/Corporation, which is funded by the

Japanese Government, and the Industrial Technology Research

Institute, which is funded partly by the Taiwanese

Government. Looking beyond the top ten reveals the Korean

Electronics & Telecommunications Research Institute, the

Japanese Agency of Industrial Science and Technology, the

National Institute for Materials Science (Japan), and the Korea

Advanced Institute of Science and Technology, all in the top

thirty filers. These are all government funded bodies. The fact

that they are so active in this area underlines the huge

investment that governments in the Far East are making in

research and development for nanoelectronics, and the

increasing interest in the Far East in protecting that

investment via the patent system. Interestingly, the only US

based players in the top ten are Hewlett Packard and the

University of California, and the only European players are

Infineon Technologies and Philips.

The top thirty players account for about 48% of the total

number of patent families in our nanoelectronics data set for

Page 9: M&C Biotech Report 06 - Marks & Clerks/… · We looked at bionanotechnology in our first Biotechnology Report in 2005. Our Nanotechnology Report 2006 expands on this field to cover

the period 2000-2005. For the top thirty, around 8% of

families were filed by European applicants. The low level of

patent filing by European applicants is surprising given the

amount of money that is being invested in nanotechnology. It

is tempting to conclude that the focus in Europe is not on

nanoelectronics but instead is on other areas of

nanotechnology. However, this is not borne out by the results

in the other two sections of this report. Another explanation is

that although committing significant amounts of public money

to nanotechnology, Europe is not protecting its investment.

Alternatively, it is possible that in Europe the wrong

investment choices are being made.

In contrast to the low level of filing activity in Europe, 24% of

the total number of patent families in the top thirty were filed

by US based applicants, and around 51% were filed by

Japanese based applicants. This difference between the US

and Japan is slightly surprising as our data suggests that

overall levels of patent filing activity by US applicants is

higher than for applicants based in the Far East. However,

differences between business strategies in the US and Japan,

and indeed the Far East more generally, provide a possible

explanation. In the US, activity is spread over a relatively large

number of players, all of whom are actively protecting

nanoelectronics innovations, whereas in the Far East activity

is focused on a relatively small number. Our data suggests

that a significant amount of the patent filing activity in

nanoelectronics in the US is by universities and small or start-

up companies, for example, SouthWest Nanotechnologies and

Nantero, which both make it into the top thirty. In contrast, in

Japan, Korea and Taiwan much of the activity is by a few large,

established companies and a relatively small number of

government funded bodies. No non-US based small or start-up

companies are in the top thirty.

page 7

Figure 5: Top 30 patent applicants over time for nanoelectronics

Source: Computer Patent Annuities Limited Partnership/Marks & Clerk ©2006

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The differences in the profiles of the nanoelectronics players

in Europe, the US and the Far East indicate fundamentally

different business approaches. Europe is investing a lot, but

protecting very little, the US is investing and protecting, but

with the focus on nurturing more small companies, and the Far

East is supporting its existing corporate entities and a

relatively small number of well-funded government institutes.

Whilst the total levels of patent filing activity are significant in

both the US and the Far East, our data indicates that there are

more players in the US. The impact of this is that available

funding is spread relatively thinly and competition for this is

high, whereas in the Far East funding is more concentrated in

the hands of a few. It remains to be seen which approach will

be the more successful in the long run.

The futureThe commercial potential for nanoelectronics is huge.

Many of the big players in the electronics arena are already

seeking ways to exploit the advantages that nanoscale

devices could provide.

We predict that activity in the Far East will remain at high

levels, and is likely to rise as nanoelectronics moves from its

current research phase increasingly towards product

development, with Japanese companies likely to be at the

front of the pack. The US market holds the promise of some

stellar start-ups, with huge investment potential. Europe is in

danger of missing the boat.

page 8

Figure 6: Highly active and emerging players for nanoelectronics

Source: Computer Patent Annuities Limited Partnership/Marks & Clerk ©2006

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Figure 7: Earliest priority filings for nanotechnology in health and personal care

Source: Computer Patent Annuities Limited Partnership/Marks & Clerk ©2006

BackgroundNanotechnology is making significant inroads into the

health and personal care sectors. Nanomedicine related

technologies are far-reaching and include, for example, drug

encapsulation and delivery, diagnostic techniques and

imaging, surgical aids, implantable devices including sensors

and prostheses and implantable materials to aid, such as

tissue and bone repair. As some companies/institutes are

developing products for use in the field of cosmetics, for

example in the dermatological field, and the US now has

some doctor endorsed cosmetic brands, this section also

covers nanotechnology when applied to cosmetics.

The marketThe potential scope in terms of applications and products in

the health and personal care sectors is almost limitless, with

new ideas and applications being developed, on a daily basis.

In terms of economic impact, an analysis of the market

segments for medical devices and drugs and pharmaceuticals

provides an insight into the potential market. These two

market segments represented in 2003 an end-user value of

€535 billion and globally this has been growing at 7-9%

annually5. The global cosmetics industry was valued at €230

billion in 20046. Therefore, even if nanotechnology related

applications were to account for only a portion of this figure,

the potential economic impact the sector may provide, is

enormous. Thus, it is very appropriate to consider the patent

landscape in this area and how this may develop in the future.

The patent landscapeOther reports have shown that patents and scientific papers

in the nanotechnology field have grown at a near exponential

rate for the past 20 years. It is interesting to see if this trend

is mirrored in the health and personal care sectors.

page 9

NANOTECHNOLOGY IN THE HEALTH AND PERSONAL CARE SECTORS

5 European technology platform on nanomedicine, September 2005

6 Euromonitor: "Cosmetics & toiletries: world market overview and key trends"In-cosmetics conference 2005

7 The health and personal care data was generated by combining the resultsfrom a number of different searches using search strings which employed"nano" as a prefix to terms, such as capsule, particle, polymer, powder,enabled, medicine, and the like, as well as other terms such as molecularelectronics, dental, hair, quantum dot, smart material.

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Figure 7 shows that the number of patent applications filed

over the last 10 years has increased at an almost

exponential rate7. However, the number of applications filed

in 2003 is only slightly higher than 2002. The apparent

slowing in 2003 filings may simply be down to a reflection of

difficult financial times in relation to the funding of

technology companies in general, at that time. It may be the

case that young and developing companies, which are likely

to be important bodies with regards to the nanomedicine

field, had to channel their finances into areas other than

patenting. It will therefore be interesting to see if the filing

numbers increase significantly in 2004 and 2005, now that

financing from various sources, including venture funds and

government sources, have increased significantly in the past

few years.

The geographical landscapeIn terms of where patent applications are being filed, the US

can be seen as having by far the largest numbers of priority

applications and granted patent publications (Figures 8 and

9), but China is also a significant first filer. Nevertheless,

international PCT (WO) applications account for nearly as

many publications compared to the US, showing perhaps the

global importance of this technology and that applicants are

looking to potentially get a broad geographical coverage of

protection for their inventions.

In Europe, in accordance with other aspects of nanotechnology,

Germany has the most priority filings. However, France has

almost as many priority filings, although this is due in part to

the significant filings by L'Oréal (see Figure 10).

As can be seen in Figure 9, patents granted in the health and

personal care arena, increased year on year from 2000 to

2004, but paradoxically, there was a decrease in 2005. Most

notably, there was a decrease in granted patents in the US and

countries listed as "other", which represents all countries not

otherwise listed and hence grouped togther. Why this should

be is difficult to speculate on, but one possibility may be that

the various patent offices are looking more carefully at the

scope of the patent applications and not awarding grant for a

variety of reasons. In 2005, the US Patent Office granted 12%

less patents than it did in 2004. Thus, the drop in granted US

nanotech patents does not seem to be a nanotech issue.

page 10

Figure 8: Earliest priority filings and grants per country in the health and personal care sectors

Source: Computer Patent Annuities Limited Partnership/Marks & Clerk ©2006

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Reverting back to Figure 8 it can be seen that the US has

granted the most cases, year on year, but the European

Patent Office (EPO), and notably the Russian Patent Office,

has also granted a significant proportion. Although China and

Japan account for the second and third highest numbers of

priority applications, these would not appear to be following

through to grant, at least as yet. In the case of Japan, this is

simply due to the delayed examination procedure adopted in

Japan, but this is not so for China. Looking at some of the

Chinese data, we can see that some applications appeared to

be jumping on the "nano" bandwagon and related to the

reformulation of a drug, at a nano-scale. The Chinese patent

examination process is quite rigorous and so maybe such

applications simply did not hold up on closer scrutiny in terms

of lacking inventiveness.

The key playersThe key players, as shown in Figure 10, come from a

varied background and include universities/government

bodies, small-to-medium sized enterprises and large

multinational companies.

L'Oréal are found to be the top patent filer in the health

and personal care fields and this is due in no small part to

the significant R&D L'Oréal conducts into nanocapsule

technology for delivering agents into the skin. L'Oréal have

observed that nanocapsules have the ability to deliver

agents such as vitamin A and retinol into deeper layers of the

skin. Agent delivery is one of the most important applications

of nanotechnology at the present time, as can be seen with

Elan Corp coming in second when this technology is applied

to pharmaceuticals as opposed to cosmeceuticals. Elan is

obviously looking to maintain its strength in the drug delivery

field and their technology has been licensed to a number of

other pharmaceutical companies.

However, it is not just about drug delivery with players like

Boston Scientific (medical devices), MIT and Philips

(diagnostics) also appearing in the top filers list. Nevertheless,

distributed throughout the list are a significant number of

publicly/government funded bodies, perhaps showing that a

great deal of the technology in the health and personal care

sectors, drug delivery aside, is very much at the early stage.

The key players are fairly split between Europe, the US and

the Far East with India also making an appearance in the top

10. Although the US has the largest number of filings, its

organisations are well represented amongst the top 10, but it

does not dominate the top 10.

The futureSo what does the future hold for nanotechnology applied to

the health and personal care sectors? Table 1 shows the

highest cited US publications for the health and personal care

sectors. The results would appear to suggest that agent

delivery and diagnostic applications are still very much to the

fore. Although universities and other publicly funded bodies

appear to be important players for now, we may see a shift to

small nanotechnology companies, in a similar fashion to that

seen in the biotech industry. Thus, early indications are that

page 11

Figure 9: Patents granted over time for nanotechnology in the health and personal care sectors

Source: Computer Patent Annuities Limited Partnership/Marks & Clerk ©2006

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the power balance in nanotechnology in the health and

personal care sectors will be more fragmented than the

power balance of nanotechnology in the electronics industry,

which is concentrated within the well-established

“conventional” technology companies.

With an ever-ageing population and significant drug patents

expiring, we would expect the pharmaceutical companies to

look closely at the nanomedicine market. This is both in terms

of trying to reformulate their blockbusters, in order to extend

market exclusively, and to look at completely new therapeutic

regimes and processes.

There are concerns that litigation is likely to ensue in some

areas of the nanomedicine field and this may lead to a lack of

confidence in the field. This may turn out to be true, but does

not appear to have occurred as yet.

On the cosmetics side, the nanocosmetics field is being led by

the specialist cosmetic companies, such as L’Oréal, and our

data shows that this trend is likely to continue.

In many areas, nanotechnology in the health and personal

care sectors is still in its infancy, but we expect an explosion

of work and patents being filed in the short to medium term.

page 12

Figure 10: Top 24 patent applicants over time for nanotechnology in the health and personal care sectors

Source: Computer Patent Annuities Limited Partnership/Marks & Clerk ©2006

Table 1: Highest cited US publications for the health and personal care sectors

Company/University Publications Families

Japan Science and Technology Corp 25 10

GeneSegues, Inc 16 2

Salvona LLC 11 3

Max-Planck Society 11 6

University of Michigan 13 6

3M 13 6

University of California 8 6

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The marketInternational concerns regarding global warming and the

potential exhaustion of fossil fuel supplies have drawn public

attention to the need to use our current energy resources more

efficiently, as well as seek alternative energy sources.

Governments in most developed countries are investing heavily

in energy research. For example, the Department of Energy is

the single largest Federal Government supporter of basic

research in the physical sciences in the US, providing more than

40% of total Federal funding to what is perceived by the US

Government to be a vital area of national importance.

Nanoenergy is the application of nanotechnology or

nanomaterials within energy applications. Nanoenergy

shows promising potential in all segments of the energy

sector: production, storage, distribution and use. The ability

to precisely control matter at atomic and molecular level can

be used to not only increase efficiency and reduce cost of

existing energy generation and conversion systems, but can

also provide new ways to create energy.

Successes have been reported in a number of areas. So far,

nanotechnology is starting to play a key role in solar cells,

thermoelectricity, batteries and fuel cells, and insulation.

Such successes encourage research across the whole spectrum

of nanoenergy. Solar cells containing nanolayers or nanorods

could significantly increase the amount of electricity converted

from sunlight by using nanostructured surfaces as more

effective light absorbers (variation of the absorbing wavelength

by quantum dots) and nanoporous electrodes. Nanomaterials of

this type can be combined with plastic electronics to develop

semiconductor polymer photovoltaics, which are both

lightweight and flexible. Research by a large range of

institutions into solar cells is ongoing, stimulating collaborations

such as that announced in 2005 between Leonhard Kurz GmbH

& Co (a German R&D company and manufacturer of polymer

electronic technology) and Konarka Technologies, with Konarka

previously having acquired Siemens’ organic photovoltaic

research activities in September 2004.

The patent landscapeAs the research activities into nanoenergy increase, there is

a corresponding increase in the relevant companies and

research institutions seeking to protect their innovations

using the patent system. Figure 11 illustrates that the

number of nanoenergy applications8 filed has steadily

risen in recent years, with over three times more patent

applications being filed in 2003 than in 20009.

The number of applications filed in the US and Europe has

increased steadily year on year, reflecting the importance of

such markets to the nanoenergy sector. The largest growth

appears to be in the filing of international (WO) patent

applications, with nearly five times as many international

patent applications being filed in 2003 than in 200010.

Presumably, this is due to many applicants using the PCT

system so as to delay the decision date regarding in which

countries to proceed, potentially reflecting the commercial

uncertainty associated with nanoenergy research.

The majority of patent applicants first file a priority

application in their own country, prior to filing foreign

applications within the 12-month priority period. Figure 12

illustrates the geographic spread of priority patent

application filings, and thus provides a good indication of the

degree of innovation within each country. The main country

in which priority applications are filed is overwhelmingly the

US, reflecting the significance of the US as a source of

innovation. Additionally, the US figure is affected by a

number of non-US applicants filing priority applications in the

US, due to the importance of the US market.

page 13

8 To search this field we used a combination of classification searching toisolate patent applications concerned with energy and then used keywordsearching within these classes to identify nanotech patents.

9 Due to the 18 month lag in publishing most patent applications, the dataonly extends up to 2003 as complete data is not yet available for 2004.

10 An International or PCT patent application is a single application whichallow an applicant to obtain provisional coverage in over 100 countries for, ingeneral, up to 30 months from the priority date. At the 30 month stage theInternational application must be converted into separate nationalapplications in the countries where the applicant requires patent protection.

NANOENERGY

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page 14

"In terms of patents, the Japanese should learn from

this report that Japan's investment in nanotechnology

in the health and personal care sectors is not as

effective as other countries, while Japan does better in

other nanotechnology fields such as nanoelectronics

and nanomaterials."

Masahiro Takemura, Senior Researcher, Nanotechnology

Researchers Network Center of Japan (Nanonet)

The next largest number of filings is made in Japan, with the

number of first filings being approximately 70% of the filings

within the US. As the population of Japan is less than half of

that of the US, this means that Japan has the largest number

of patent filings in this sector per head of the population

which is an indication of how significant the sector is seen to

the Japanese economy. The lack of Japan’s own oil reserves

may be a factor for the country’s commitment to emerging

energy technology. In general, the Far East dominates the

nanoenergy sector with South Korea (77) and China (43) both

having significant numbers of priority filings.

Europe is rather poorly represented in the nanoenergy league

with the highest number of first filings from Germany (35),

ahead of both the UK (18) and France (10). In addition to the

European figures shown in Figure 12, there were 28 priority

filings at the EPO for the same period. Adding together the

total number of priority filings for Europe, the total is less

than 40% of the total number for Japan. However, on a

positive note, Europe’s slow start in this rapidly developing

field is being monitored and the European Commission has

focused on nanoenergy as one of its three key areas for

driving nanotechnology in Europe.

Nanoenergy spans such a wide range of technologies that it

is not sensible to assume that every energy field which may

benefit from nanotechnology, will actually benefit. Some of

the patents filed now will be deemed to be worthless, but

some will prove to be of great value. A valuable patent in an

emerging technology takes time to establish itself.

However, an early indication of a valuable patent is the

number of times the patent is used to prevent others from

obtaining their patents i.e. the number of times it is cited

during the examination procedures for other patents.

Already there are certain patents relating to photoelectric

devices, fuel cells and catalysts in batteries using

nanotechnology which are being cited more frequently than

others. These patents may prove to be of great value to those

who own them.

Figure 11: Patent applications over time for nanoenergy

Source: Computer Patent Annuities Limited Partnership/Marks & Clerk ©2006

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The key playersThe key applicants for nanoenergy related patents are

shown in Figure 13. Surprisingly, none of the well-known

conventional energy companies feature in the top 20.

Although the application of nanotechnology to the energy

industry tends to complement the electronics side as

opposed to the fossil fuel side of the industry, many of

the fossil fuel energy companies are now trying

to portray themselves as dealing in all forms of energy.

Therefore, we would have expected at least one of

these companies to feature somewhere in the top 20.

Also, many of the applications relate to improvements in

battery technology, but the well-known western battery

manufacturers are also missing from our top 20.

However, our results cannot identify if a well-established

energy company is directly or indirectly investing in

start-ups.

The two dominant countries in nanoenergy are the US and

Japan. However, the dominant players in the nanoenergy field

show that both countries have a considerably different

approach to the nanoenergy sector. The key player list is

dominated by large Japanese multinational companies,

whereas the highest placed US applicant is Californian

Institute of Technology.

Japan is really trying to drive nanoenergy applications forward

with many of the well-known Japanese multinationals having

page 15

Figure 12: Priority countries for nanoenergy

Source: Computer Patent Annuities Limited Partnership/Marks & Clerk ©2006

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significant filings in this field and Japanese companies

representing 3 of the top 5 filers. Sony Corporation has filed

over 50 nanoenergy patent families since 2000. Many of the

Sony applications relate to improvements in fuel cells,

reflecting the perceived demand for improved fuel cells within

both the automobile and aircraft industries.

Although the US has a higher number of priority filings than

Japan, the US nanoenergy patent landscape is very

fragmented, but this may be due to the popularity of venture

funds in the US. It has been estimated that 41 out of the top

50 R&D companies in the US are either originally venture-

backed or are major acquirers of venture-backed companies11.

In second place in our key player list is the Korean giant,

Samsung. South Korea is the third in our country list, but there

are still five times as many US priority applications than South

Korean priority applications. Thus, the fact that a South

Korean multinational is comfortably in second place ahead of

all US companies is surprising. As for nanoelctronics, the

Samsung data comprises both that of Samsung Electronics

(11 patent families) and Samsung SDI (17 patent families).

Treating both Samsung companies as separate entities would

still have seen both companies feature in our top 10.

Although we have noted that Europe was lagging behind

both the Far East and US, there are signs of a change in

Europe when looking at key players. Both Philips and the

Hahn-Meitner-Institut Berlin filed more applications in the

past two years than many of the higher placed key players.

page 16

Figure 13: Top patent filers for nanoenergy related applications

Source: Computer Patent Annuities Limited Partnership/Marks & Clerk ©2006

11 http://www.nvca.org/pdf/VentureImpact2004release.pdf

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Figure 14: Highly active and emerging players for nanoenergy

Source: Computer Patent Annuities Limited Partnership/Marks & Clerk ©2006

page 17

The futureOur results show that the power balance in nanoenergy is

predominantly held by the large electronics companies from

the Far East. If nanoenergy lives up to its promise then the

world may see the power balance in our energy supplies shift

from the US to the Far East.

Figure 14 illustrates how six of the most significant

companies are filing relevant patent applications at an

increasing rate, emphasizing the increased commercial

significance attached to the nanoenergy technology area by

such companies. The technology promises much across a

range of applications, and has potential to change the way

we convert, store and utilise the world’s energy supply. The

increasing rate of patent filings from these companies shows

that they will continue their dominance in this field.

Europe is lagging behind the rest of the world by some

margin in the nanoenergy field. To ensure that European

companies are not left behind, the European commission has

identified nanoenergy as one of its key three areas. This may

already be having an effect as European companies are

starting to fight back.

The rapid growth of patenting in the nanoenergy sector

suggests that many see nanotechnology as a means for

addressing some of the world’s energy problems. Our results

suggest that the conventional energy companies are possibly

being left behind in the race to patent nanoenergy. This could

be an early indicator that the power of the existing energy

giants is starting to wane. However, it is also possible that

many of the current giants of the industry are investing in

start-ups.

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This report has shown that the dominant country for both filing patents and granting patents in all three sectors is the US.

However, the Far East and especially Japan is not far behind in both nanoelectronics and nanoenergy.

The power balance of nanotechnology in the US and the Far East is very different. In both nanoenergy and nanoelectronics, the

large Japanese electronic companies and the Korean giant Samsung dominate the patent landscape. In the US, the market is split

between start-ups and universities with some notable exceptions such as Hewlett Packard.

The picture for nanotechnology in the health and personal care sectors is far more fragmented than that for nanoelectronics

and nanoenergy. Although again the US has the highest number of filings, European companies feature strongly amongst the

key players.

Our results suggest the continued dominance of the Far East giant companies over the coming years, but the start-ups from the

US should not be ignored. Thirty years ago Microsoft was a US start-up and is now the world’s largest software company with a

current market value of approximately $280 billion12. Unlike a software company, a nanotechnology company must invest heavily

in R&D to progress. Patents provide security for R&D investment and we expect to see a steady rise in the number of

nanotechnology patents over the next few years.

page 18

12 April 2006 http://www.forbes.com/lists/2006/18/Rank_1.html

CONCLUSIONS

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If you have any questions about this report, or would like more information, contact one of the authors from our

Nanotechnology Group:

Dr. Rhian Granleese Dr. Paul Chapman

UK & European Patent Attorney UK & European Patent Attorney

90 Long Acre 19 Royal Exchange Square

London, WC2E 9RA, UK Glasgow, G1 3AE, UK

T: + 44 (0)207 420 0000 T: +44 (0)141 221 5767

E: [email protected] E: [email protected]

Dr. Maureen Kinsler Neil Parkinson

UK & European Patent Attorney UK & European Patent Attorney

19 Royal Exchange Square Sussex House

Glasgow, G1 3AE, UK 83-85 Mosley Street

T: +44 (0)141 221 5767 Manchester, M2 3LG, UK

E: [email protected] T: +44 (0)161 233 5800

E: [email protected]

About Marks & ClerkMarks & Clerk is recognised internationally as one of the leading firms of patent and trade mark attorneys. Our highly

qualified attorneys advise clients in all sectors on acquiring, securing and registering intellectual property (IP) rights and

managing IP portfolios. They have notable expertise and experience in both traditional and cutting edge technologies from

biotechnology and nanotechnology to electronics and engineering.

With a network of offices in the UK (12 locations), Europe, North America and the Far East and long-established

relationships with other leading IP firms worldwide, Marks & Clerk is well placed to meet clients’ IP requirement locally

and globally.

Winner of the Managing Intellectual Property Global Award for Leading Firm in Europe for Patents 2006

Ranked the no.1 firm in the UK for patents in the Managing Intellectual Property World IP Annual Survey 1997-2006

www.marks-clerk.com

MARKS & CLERK CONTACTS

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© Copyright Marks & Clerk 2006

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