8/19/2019 MCQ 2554-7

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- ............................................................................................ ................... .........… 2 (MCQ12)

1/2554 6 . . 255 4 09.00-12.00 .

1 : 80 60 acute renalfailure Scr = 2 mg/dL , K =7 mmol/L ( ) atenolol, simvastatin, aspirin, ketoconazole felodipine

1. creatinine clearance . 10 mL/min

. 15 mL/min

. 20 mL/min

. 25 mL/min

. 30 mL/min

2. acute renal failure . hypovolume

. bleeding

. rhabdomyolysis

. nephrotoxic

. 3. oliguria

. .

. . .

4. . atenolol . hydralazine

. simvastatin . felodipine

. aspirin

5. . dextrose + insulin . calcitriol

. erythropoietin . calcium carbonate

. sodium bicarbonate

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6. oral corticosteroids. hyperkalemia . hyperphosphatemia

. hyponatremia . hyperchloremic

. hypocalcemia

7. ( steroids ) 8. %label amount sodium bicarbonate injection pH

1 + +antioxidant

pH 2 95% 95% 95%

pH 4 95% 95% 98%

pH 7 87% 87% 90%

pH 10 70% 70% 80%

sodium bicarbonate injection. pH 2 antioxidant

. pH 4 antioxidant

. pH 4

. pH 7 . pH 10 9.

. oxidation

. photolysis

. hydrolysis

. oxidation photolysis . oxidation hydrolysis

10. .

. 15%. 5%. 25%. 10%

8/19/2019 MCQ 2554-7

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2 : 76 1 levodopar/benserazide 25/100 mg

11.benserazide levodopar . peripheral

. levodopar. levodopar. levodopar blood brain barrier

. levodopar 12. levodopar levodopar/benserazide 25/100 mg

. pergolide

. ondansetron

. selegiline

. carbidopa

. trihexylphenidyl

13. levodopa

. .

.

. .

14. levodopa . rigidity

. dyskinesia

. hallucination. somnolence

. gynecomastia

15. . benztropine . trihexylphenidyl

. amitriptyline . chlorpheniramine

. domperidone

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16. benserazide enzyme . MAOB

. COMT

. acetylcholine esterase

. dopa decarboxylase

. dopa deaminase

17. levodopa . oxidation

. methylation

. esterification

. decarboxylation

. deamination

18. levodopar/benserazide sustained release . compliance

. on-off phenomenon

.

.

.

19. A1 A2 276 286 C . amorphous crystalline

. A1 crystalline

. A2 amorphous

. amorphous crystalline

. A1 A220. OTOP

. . . .

. ( )

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3 : 5

21.

.

. .

.

. 22. 3

. povidone-iodine

. alcohol 70%

. alcohol 90%

. . contact lens

23. . S.aureus

. S.pneumoniae

. E.coli

. P. acne

. P. aeruginosa

24. . ketoconazole

. imipenam

. tetracycline. amoxicillin

. cloxacillin

25. . bacitracin . calamide lotion

. mupirocin . acyclovir

. fusidic acid

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26.

27. .

.

.

.

.

28. .

. . .

. 29.

. 000

. 0

. 1

. 2

. 3

30.alcohol 70% 30 .

.

.

. . 3

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4 : 31.

.

.

.

. metabolic syndrome

.

32.

. . . . .

33. hyperthyroidism. grave’s disease

. hashimoto

. . . euthyroid baseline hyperthyroidism

34. PTU . methimazole

. . . SSKI.

35. methimazole

. bleeding

. anemia

. nephrotoxic

. agranulocytosis

. osteoporosis

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36. . PTU

. Lugol’s solution

. methimazole

. propranolol

. L-thyroxine

37. KI 3 mmol/L ( MW KI 166 g). KI 0.50 g 1

. KI 5.00 g 1 . KI 5.50 g 1 . KI 50.00 g 1 . KI 55.00 g 1

38. KI+I 2 . complexation

. trituration

. emulsification

. suspension

. levigation

39. KI+I2

. KI I2 KI I2

. KI I2 I2 KI. I2 KI . KI I2 .

40. 27 2553 .

. . . . 1%

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5 : 56 41.

. herpes zoster

. herpes simplex

. varicella zoster virus

. treponema pallidum

. Human papilloma virus

42. .

. paracetamol. cloxacillin . .

43. . celecoxib

. aspirin

. tramadol

. paracetamol

. amitriptyline

44. acyclovir

. 200 mg 5 7 . 200 mg 5 14 . 800 mg 5 7 . 800 mg 5 14 . 800 mg 3 7

45. .

. .

.

.

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46. acyclovir. RNA polymerase

. triphosphate . product valacyclovir. . promotion DNA

47. .

.

.

.

.

48.-49. emulsion 2 %creaming ( )50.

. . . . .

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6 : 31 onychomycosis51.

. Trichophyton rubrum

. Candida albican

. Malassezia furfur

. Pityrosporum orbiculare

. Herpes simplex

52. . ketoconazole

. griseofulvin

. prednisolone

. hydroxyzine

. cloxacillin

53. 52 . 1

. 1

. 3

. 6 . 12

54. 52 . ketoconazole

. itraconazole

. prednisolone

. nystatin. cloxacillin

55. itraconazole . CYP1A2

. CYP2D6

. CYP3A4

. CYP2C9

. CYP2C19

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56. amphotericin. superoxide dismutase

. permeability.

14

-reductase

. DNA. uptake

57. . ointment

. cream

. lacquer

. spray

. lotion

58. itraconazole bioavaliability . intranasal

. . suppository

. intramuscular injection

. skin patch

59. ( )60. 2 A B

utility

A 1,500,000 0.75

B 1,200,000 0.7

. A . B . A utility . B .

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7 : 24

61. . Gouty arthritis

. Rheumatoid arthritis

. Osteoarthritis

. Osteoporosis

. Osteopenia

62. . paracetamol

. colchicine

. prednisolone

. ibuprofen

. methotrexate

63. 62 . sulfasalazine

. Auranofin

. celecoxib

. glucosamine

. allopurinol

64. . estrogen

. methotrexate

. paracetamol. glucosamine

. probenecid

65.

66.

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67.

.

. sulfonamides.

. / . 68.

. croscarmellose. talcum

. povidone K

. gelatin

. methyl cellulose

69. dissolution test celecoxib monograph Q = 80% 12 84% 65%

. S1

. S2

. S3

. S1 S2. S2 S3

70. . celecoxib

. glucosamine

. colchicine

. diclofenac

. prednisolone

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8 : 72 (myocardialinfarction)

71. . creatinine kinase

. Alkaline phosphatase

. Ejeculation function

. Calcitonin

. Electrocardiogram

72. ISDN 3

. aspirin grain V . aspirin grain III . aspirin grain V

. ISDN . ISMN

73. cGMP. nifedipine

. enalapril

. metoprolol

. nitroglycerine

. furosemide

74. . morphine sulfate

. verapamil. metoprolol

. ISDN

. HCTZ

75. vasospasm . verapamil . nitroglycerine

. enalapril . furosemide

. metoprolol

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76. aspirin

. stent . . . .

77. metoprolol ( )

.

.

.

.

.

8/19/2019 MCQ 2554-7

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78. aspirin . sustained release

. modified release

. enteric coated

. film coated

. sugar coated

79. sustained release. PEG

. Eudragit E

. methyl cellulose

. ethyl cellulose

. HPMC

80. ( )( patent)

20

20

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9 : 41 Hb = 9, Hct = 30,

81. . folate deficiency anemia

. thalassemia

. vitamin B6 deficiency anemia

. vitamin B12 deficiency anemia

. iron deficiency anemia

82. . ferrous sulfate

. folic acid

. cobalamine

. pyridoxine

. deferoxamine

83. . folate deficiency anemia

. thalassemia

. osteoporosis

. peptic ulcer

. iron deficiency anemia

84.

.

.

.

. . GI discomfort

85. . tetracycline

. folic acid

. vitamin B12

. vitamin C . omeprazole

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86. . ketoconazole . vitamin B12

. vitamin C . aspirin

. folic acid

87. ( Fe 55). ferrous fumarate (MW = 170)

. ferrous gluconate (MW = 448)

. ferrous citrate (MW = 246)

. ferrous sulfate. 7H 2O (MW = 278)

. anhydrous ferrous sulfate (MW = 152)

88. Ferrous Sulfate 12.50 g

Citric Acid 0.20 g

Syrup q.s. 100.00 ml

.

.

. . .

89. . Polarimeter

. MS

. HPLC

. IR

. Atomic absorption spectrometer90.Ferrous sulfate 100

. 3.

.

. 3.

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10 : 29 penicillin

91. . Rhino virus . Influenza virus

. S. pyogenes .

. S. aureus

92. . paracetamol . expectorants

. antibiotics . antitussive

. mucolytics

93. . amoxicillin . clindamycin

. amoxicillin + clavulanic acid . clarithromycin

. metronidazole

94. . clindamycin 30S ribosome . erythromycin 50S ribosome

. gentamicin 30S ribosome . sulfonamide . amoxicillin

95. . clindamycin . amoxicillin + clavulanic acid

. ampicillin . tetracycline

. azithromycin

96. G6PD . tetracycline . clindamycin

. amoxicillin . cephalexin

. norfloxacin

97. binder. pregelatinized starch . dicalcium phosphate

. sodium CMC . sodium starch glycolate

. magnesium sterate

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98. macrolides

.

.

.

.

.

99. disintegration time 35 . sodium starch glycolate . colloidal silica

. dicalcium phosphate . gelatin

. magnesium sterate

100. 60 . 3

.

.

. 3.

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11 : 40 54 150 5-Fluorouracil 150 mg/m 2 , methotrexate 30 0

mg/m 2 cyclophosphamide 100 mg/m 2

101. BSA . 0.67

. 1.3

. 1.5

. 2.0

. 2.4

102. cyclophosphamide . 130 mg

. 150 mg

. 200 mg

. 225 mg

. 450 mg

103. cyclophosphamide . hemorrhagic cystitis

. hepatotoxic

. thrombocytopenia

. cardiac conduction

. alopecia

104. cyclophosphamide. doxorubicin

. 5-FU. cisplatin

. etoposide

. viscristine

105. methotrexate

. hemorrhagic cystitis . cardiac conduction

. stromatitis . alopecia

. thrombocytopenia

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106. cytotoxic 5-FU. dexamethasone

. odansetron

. folic acid

. allopurinol

. leucovorin

107. metrothexate 1 2.5 mg 2.5 mg / 5 mL 2 27

. 27 5 mL

. 27 135 mL

. 27 270 mL

. 54 135 mL

. 54 270 mL

108. emulsifier

potassium sterate

109. suspension. coalescent

. caking

. breaking

. cracking

. picking

110. metrothexate .

.

.

. 3 . 4

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12 : 2 2 /

111. . B. cereus

. S. aureus

. E. coli

. Rotavirus

. Adenovirus

112. . ORS

. diphenoxylate

. loperamide

. hyoscine

. norfloxacin

113. diphenoxylate

.

.

.

. .

114. ORS sodium . 180 mEq/L

. 120 mEq/L

. 100 mEq/L. 90 mEq/L

. 75 mEq/L

115. sodium (mEq/L) ORS NaCl 0.40 g (MW = 58 g.)

KCl 0.30 g (MW = 74 g.)

Na citrate dihydrate 0.50 g (MW = 294 g.)

qs 250 mL. ( )

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116. glucose displacement value 1.1 glucosesyrup glucose 1% 20

. 19.00

. 19.78

. 19.80

. 20.00

. 20.22

117.

118. 20 metronidazole 1x3 pc 7.5 mg/kg/day

. 7.5 mg

. 20 mg

. 50 mg

. 150 mg

. 450 mg

119. suspension flocculating agentsuspending agent

. + , +

. - , -

. + , -

. - , +

.

120. ORS

.

.

.

.

.