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MEASUREMENTS OF EYE LENS DOSES IN ......NIOM SCK Average all 1,91 1,67 2,14 Median all 1,90 1,52...

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MEASUREMENTS OF EYE LENS DOSES IN INTERVENTIONAL RADIOLOGY AND CARDIOLOGY: FINAL RESULTS OF THE ORAMED PROJECT F. Vanhavere 1 , E. Carinou 2 , J. Domienik 3 , L. Donadille 4 , M. Ginjaume 5 , G. Gualdrini 6 , C. Koukorava 2 , S. Krim 1 , D. Nikodemova 7 , N. Ruiz- Lopez 8 , M. Sans-Mercé 8 , L. Struelens 1 1 Belgian Nuclear Research Centre (SCK•CEN), Belgium 2 Greek Atomic Energy Commission (GAEC), Greece 3 Nofer Institute of Occupational Medicine, Lodz, Poland 4 Institut de Radioprotection et de Sûreté Nucléaire (IRSN), France 5 Universitat Politecnica de Catalunya (UPC), Barcelona, Spain 6 ENEA Radiation Protection Institute, Bologna, Italy 7 Slovak Medical University Faculty, Bratislava, Slovakia 8 Institute of Radiation Physics (IRA), University Hospital Center and University of Lausanne, Switzerland
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Page 1: MEASUREMENTS OF EYE LENS DOSES IN ......NIOM SCK Average all 1,91 1,67 2,14 Median all 1,90 1,52 1,07 Average >0.1mSv-1,15 1,18 Median >0.1mSv-1,15 1,11! Good agreement, no need to

MEASUREMENTS OF EYE LENS DOSES IN INTERVENTIONAL RADIOLOGY AND

CARDIOLOGY: FINAL RESULTS OF THE ORAMED PROJECT

F. Vanhavere1, E. Carinou2, J. Domienik3, L. Donadille4, M. Ginjaume5, G. Gualdrini6, C. Koukorava2, S. Krim1, D. Nikodemova7, N. Ruiz-Lopez8, M. Sans-Mercé8, L. Struelens1

1 Belgian Nuclear Research Centre (SCK•CEN), Belgium2 Greek Atomic Energy Commission (GAEC), Greece3Nofer Institute of Occupational Medicine, Lodz, Poland4Institut de Radioprotection et de Sûreté Nucléaire (IRSN), France5Universitat Politecnica de Catalunya (UPC), Barcelona, Spain6ENEA Radiation Protection Institute, Bologna, Italy7Slovak Medical University Faculty, Bratislava, Slovakia8 Institute of Radiation Physics (IRA), University Hospital Center and University of

Lausanne, Switzerland

Page 2: MEASUREMENTS OF EYE LENS DOSES IN ......NIOM SCK Average all 1,91 1,67 2,14 Median all 1,90 1,52 1,07 Average >0.1mSv-1,15 1,18 Median >0.1mSv-1,15 1,11! Good agreement, no need to

Importance of eye lens doses?o Cataract: “loss of transparancy of the lens of the eye”

o Associated with aging and with metabolic conditions likediabetes

o Also radiation-inducedo Present status radiation protection ICRP

o Cataract induction = deterministic effect with definitethreshold

o Acute exposure: 0.5-2 Gyo Prolonged exposure: 5-6 Gy

o Latency period that can last for decadeso dose limits:

o 150 mSv/year for professionally exposureo Operational quantity: Hp(3)

o Not measured in practise

Page 3: MEASUREMENTS OF EYE LENS DOSES IN ......NIOM SCK Average all 1,91 1,67 2,14 Median all 1,90 1,52 1,07 Average >0.1mSv-1,15 1,18 Median >0.1mSv-1,15 1,11! Good agreement, no need to

Recent developmentso Epidemiological studies:

o Bomb survivors, Chernobyl clean up workers,radiological technologists,…

o High probability that threshold dose <0.8 Gyo Not certain there is a thresholdo Current limit is too high…

o Different activities are on-going:o ICRP, IAEA, many scientific studies,…o next talks will also focuss on this problem

o Now we will focuss on the ORAMED results on eye lenses

Page 4: MEASUREMENTS OF EYE LENS DOSES IN ......NIOM SCK Average all 1,91 1,67 2,14 Median all 1,90 1,52 1,07 Average >0.1mSv-1,15 1,18 Median >0.1mSv-1,15 1,11! Good agreement, no need to

ORAMED measurements of eye lens doses

Page 5: MEASUREMENTS OF EYE LENS DOSES IN ......NIOM SCK Average all 1,91 1,67 2,14 Median all 1,90 1,52 1,07 Average >0.1mSv-1,15 1,18 Median >0.1mSv-1,15 1,11! Good agreement, no need to

Measurement campaign:• 6 different countries, • 3 hospitals per country• 8 types of procedure• 10 measurements/type of procedure/hospital

Interventional Cardiology:• CA and PTCA• RF Ablations (RFA)• Pacemakers and Cardiac Defibrillator Implantations (PM/CD)

ORAMED measurements in IR/IC

3 Cardiology 5 Radiology>1300

measurements

Interventional Radiology:• Angiography (DSA)/Angioplasty (PTA)o Lower limbs (LL)o Carotids and Brain ( C/B)o Renal• Embolisations• Endoscopic retrograde cholangiopancreatographyprocedures (ERCP)

Page 6: MEASUREMENTS OF EYE LENS DOSES IN ......NIOM SCK Average all 1,91 1,67 2,14 Median all 1,90 1,52 1,07 Average >0.1mSv-1,15 1,18 Median >0.1mSv-1,15 1,11! Good agreement, no need to

ORAMED measurements?

o All IR and IC procedures frommeasurement campaign

o Two measurement for eye doseso Middle eyeo Left/right eye

o Depending on tube locationo TLD in bago Calibrated in Hp(0,07)

Page 7: MEASUREMENTS OF EYE LENS DOSES IN ......NIOM SCK Average all 1,91 1,67 2,14 Median all 1,90 1,52 1,07 Average >0.1mSv-1,15 1,18 Median >0.1mSv-1,15 1,11! Good agreement, no need to

New RADCARD eye lens dosemeter: EYE-D™

o Now measurements in terms of Hp(3)o Available at the end of the project

o Comparison between TLD in bag Hp(0.07) andTLD in eye lens dosemeter Hp(3)

o Tests in hospitals and labs

Page 8: MEASUREMENTS OF EYE LENS DOSES IN ......NIOM SCK Average all 1,91 1,67 2,14 Median all 1,90 1,52 1,07 Average >0.1mSv-1,15 1,18 Median >0.1mSv-1,15 1,11! Good agreement, no need to

Comparison Hp(0,07) and Hp(3) measurements in lab

Hp(3)/Hp(0.07)

UPC NIOM SCK

N-60 1,01 1,02 1,01

N-80 1,02 0,96 1,03

! Not much difference in calibration values

Ratio of calibration coefficients: [cts/µSv]Hp(3)/[cts/µSv]Hp(0.07)

Hp(3): eye lens dosemeter, cylindrical phantom, ENEA conversion coefficentsHp(0.07): bag, slab phantom, ISO conversion coefficients

Page 9: MEASUREMENTS OF EYE LENS DOSES IN ......NIOM SCK Average all 1,91 1,67 2,14 Median all 1,90 1,52 1,07 Average >0.1mSv-1,15 1,18 Median >0.1mSv-1,15 1,11! Good agreement, no need to

Comparison Hp(0,07) and Hp(3) measurements in hospitals

Per procedure, simultaneous measurement with eye lens dosemeter and bag

0,10

1,00

10,00

0,000 0,050 0,100 0,150 0,200

Hp(

3)/H

p(0.

07)

Hp(0.07) [mSv]

SCK-CEN

NIOM

GAEC

CHUV

Page 10: MEASUREMENTS OF EYE LENS DOSES IN ......NIOM SCK Average all 1,91 1,67 2,14 Median all 1,90 1,52 1,07 Average >0.1mSv-1,15 1,18 Median >0.1mSv-1,15 1,11! Good agreement, no need to

Comparison Hp(0,07) and Hp(3) measurements in hospitalsHp(3)/

Hp(0.07)GAEC NIOM SCK

Averageall

1,91 1,67 2,14

Medianall

1,90 1,52 1,07

Average >0.1mSv

- 1,15 1,18

Median>0.1mSv

- 1,15 1,11

! Good agreement, no need to change ORAMED measurement data

Page 11: MEASUREMENTS OF EYE LENS DOSES IN ......NIOM SCK Average all 1,91 1,67 2,14 Median all 1,90 1,52 1,07 Average >0.1mSv-1,15 1,18 Median >0.1mSv-1,15 1,11! Good agreement, no need to

Results of eye lens dose measurements

Page 12: MEASUREMENTS OF EYE LENS DOSES IN ......NIOM SCK Average all 1,91 1,67 2,14 Median all 1,90 1,52 1,07 Average >0.1mSv-1,15 1,18 Median >0.1mSv-1,15 1,11! Good agreement, no need to

STATISTICS WITH THE USE OF THE PERSONAL PROTECTIVE EQUIPMENT

Percentage of personal protection

lead apron, lead collar, glasses

25%

none1%

lead apron12%

lead apron, lead collar 62%

Interventional cardiology

Interventional radiology

Page 13: MEASUREMENTS OF EYE LENS DOSES IN ......NIOM SCK Average all 1,91 1,67 2,14 Median all 1,90 1,52 1,07 Average >0.1mSv-1,15 1,18 Median >0.1mSv-1,15 1,11! Good agreement, no need to

ORAMED results: comparison of different procedures

0,00

0,50

1,00

1,50

2,00

2,50

3,00

3,50

4,00

4,50

L/R Eye

Middle Eye

L/R Eye

Middle Eye

L/R Eye

Middle Eye

L/R Eye

Middle Eye

L/R Eye

Middle Eye

L/R Eye

Middle Eye

L/R Eye

Middle Eye

L/R Eye

Middle Eye

Hp(

0.07

) (m

Sv)

Hp(0.07)

median

average

Eyes

CA/PTCA RF Ablations PM/ICD DSA/PTA Lower Limbs DSA/PTA Renal DSA/PTA

Cer/CarEmbolisations ERCP

- L/R eye always higher than Middle eye- Some very high values/procedure

Page 14: MEASUREMENTS OF EYE LENS DOSES IN ......NIOM SCK Average all 1,91 1,67 2,14 Median all 1,90 1,52 1,07 Average >0.1mSv-1,15 1,18 Median >0.1mSv-1,15 1,11! Good agreement, no need to

Highest eye lens doses in embolizations(median around 60µSv/per procedure)

0,00

0,05

0,10

0,15

0,20

0,25

0,30

0,35

0,40

L/R Eye

Middle Eye

L/R Eye

Middle Eye

L/R Eye

Middle Eye

L/R Eye

Middle Eye

L/R Eye

Middle Eye

L/R Eye

Middle Eye

L/R Eye

Middle Eye

L/R Eye

Middle Eye

Hp(

0.07

) (m

Sv)

Hp(0.07)

medianaverage

Eyes

CA/PTCA RF Ablations PM/ICD DSA/PTA Lower Limbs

DSA/PTARenal

DSA/PTA Cer/Car

Embolisations

ERCP

Page 15: MEASUREMENTS OF EYE LENS DOSES IN ......NIOM SCK Average all 1,91 1,67 2,14 Median all 1,90 1,52 1,07 Average >0.1mSv-1,15 1,18 Median >0.1mSv-1,15 1,11! Good agreement, no need to

Highest eye lens doses in PM (per KAP)

0,0E+00

2,0E-05

4,0E-05

6,0E-05

8,0E-05

1,0E-04

L/R Eye

Middle Eye

L/R Eye

Middle Eye

L/R Eye

Middle Eye

L/R Eye

Middle Eye

L/R Eye

Middle Eye

L/R Eye

Middle Eye

L/R Eye

Middle Eye

L/R Eye

Middle Eye

Hp(

0.07

) /K

AP

(m

Sv/μ

Gym

2 )

Hp(0.07)/KAP

median

average

Eyes

CA/PTCA RF Ablations PM/ICD DSA/PTA Lower Limbs

DSA/PTARenal

DSA/PTA Cer/Car

Embolisations

ERCP

Page 16: MEASUREMENTS OF EYE LENS DOSES IN ......NIOM SCK Average all 1,91 1,67 2,14 Median all 1,90 1,52 1,07 Average >0.1mSv-1,15 1,18 Median >0.1mSv-1,15 1,11! Good agreement, no need to

Influence factors on eye lens doses

Page 17: MEASUREMENTS OF EYE LENS DOSES IN ......NIOM SCK Average all 1,91 1,67 2,14 Median all 1,90 1,52 1,07 Average >0.1mSv-1,15 1,18 Median >0.1mSv-1,15 1,11! Good agreement, no need to

ERCP: ceiling shield important for tube above: Factor 5 to 8 dose reduction

Page 18: MEASUREMENTS OF EYE LENS DOSES IN ......NIOM SCK Average all 1,91 1,67 2,14 Median all 1,90 1,52 1,07 Average >0.1mSv-1,15 1,18 Median >0.1mSv-1,15 1,11! Good agreement, no need to

Embolizations: ceiling shield important : Factor 3 to 7 dose reduction

Page 19: MEASUREMENTS OF EYE LENS DOSES IN ......NIOM SCK Average all 1,91 1,67 2,14 Median all 1,90 1,52 1,07 Average >0.1mSv-1,15 1,18 Median >0.1mSv-1,15 1,11! Good agreement, no need to

Embolizations: tube below gives lower eye lens doses: Factor of 8-20 dose reduction

Page 20: MEASUREMENTS OF EYE LENS DOSES IN ......NIOM SCK Average all 1,91 1,67 2,14 Median all 1,90 1,52 1,07 Average >0.1mSv-1,15 1,18 Median >0.1mSv-1,15 1,11! Good agreement, no need to

CA/PTCA: ceiling shield important : Factor 1.5 to 2.5 dose reduction

Page 21: MEASUREMENTS OF EYE LENS DOSES IN ......NIOM SCK Average all 1,91 1,67 2,14 Median all 1,90 1,52 1,07 Average >0.1mSv-1,15 1,18 Median >0.1mSv-1,15 1,11! Good agreement, no need to

CA/PTCA: no clear influence of access on eyelens doses

Page 22: MEASUREMENTS OF EYE LENS DOSES IN ......NIOM SCK Average all 1,91 1,67 2,14 Median all 1,90 1,52 1,07 Average >0.1mSv-1,15 1,18 Median >0.1mSv-1,15 1,11! Good agreement, no need to

RF ablations: ceiling shield reduces the eyelens doses with around 50%

Page 23: MEASUREMENTS OF EYE LENS DOSES IN ......NIOM SCK Average all 1,91 1,67 2,14 Median all 1,90 1,52 1,07 Average >0.1mSv-1,15 1,18 Median >0.1mSv-1,15 1,11! Good agreement, no need to

Extrapolation to annual doses

Page 24: MEASUREMENTS OF EYE LENS DOSES IN ......NIOM SCK Average all 1,91 1,67 2,14 Median all 1,90 1,52 1,07 Average >0.1mSv-1,15 1,18 Median >0.1mSv-1,15 1,11! Good agreement, no need to

Extrapolation to annual eye lens doses

o For all participating operators we have tried tocalculate the annual doses

o Use of annual workload (# procedures)o From logbooko From personal contact

o Multiplied with average doses measuredo Often underestimation, because they perform other

procedures that are not measured

o Category A workers if 3/10th of limit can bereachedo Monitoring required

Page 25: MEASUREMENTS OF EYE LENS DOSES IN ......NIOM SCK Average all 1,91 1,67 2,14 Median all 1,90 1,52 1,07 Average >0.1mSv-1,15 1,18 Median >0.1mSv-1,15 1,11! Good agreement, no need to

Annual doses ERCP: Low, monitoring normally not needed

Operator Procedure#

proceduresAnnual

dose [mSv]1 ERCP 100 502 ERCP 107 3,93 ERCP 30 0,34 ERCP 70 0,65 ERCP 110 26 ERCP 100 0,27 ERCP 300 0,48 ERCP 1281 179 ERCP 689 6

10 ERCP 70 0,711 ERCP 107 512 ERCP 250 213 ERCP 125 1,214 ERCP 150 1,415 ERCP 230 216 ERCP 36 3,417 ERCP 150 9

Page 26: MEASUREMENTS OF EYE LENS DOSES IN ......NIOM SCK Average all 1,91 1,67 2,14 Median all 1,90 1,52 1,07 Average >0.1mSv-1,15 1,18 Median >0.1mSv-1,15 1,11! Good agreement, no need to

Annual doses CA/PTCA:Can be high, monitoring recommended

Operator Procedure#

proceduresAnnual

dose [mSv]1 CA/PTCA 260 102 CA/PTCA 230 283 CA/PTCA 750 474 CA/PTCA 1200 695 CA/PTCA 1000 466 CA/PTCA 710 107 CA/PTCA 900 268 CA/PTCA 600 119 CA/PTCA 630 11

10 CA/PTCA 630 1211 CA/PTCA 500 512 CA/PTCA 1000 2713 CA/PTCA 500 3014 CA/PTCA 600 915 CA/PTCA 1100 9

Page 27: MEASUREMENTS OF EYE LENS DOSES IN ......NIOM SCK Average all 1,91 1,67 2,14 Median all 1,90 1,52 1,07 Average >0.1mSv-1,15 1,18 Median >0.1mSv-1,15 1,11! Good agreement, no need to

Annual doses PM&ICD:Low, monitoring not required

Operator Procedure#

proceduresAnnual

dose [mSv]1 PM&ICD 44 1.12 PM&ICD 400 313 PM&ICD 100 6.14 PM&ICD 100 1.65 PM&ICD 110 0.16 PM&ICD 100 0.27 PM&ICD 144 1.2

Page 28: MEASUREMENTS OF EYE LENS DOSES IN ......NIOM SCK Average all 1,91 1,67 2,14 Median all 1,90 1,52 1,07 Average >0.1mSv-1,15 1,18 Median >0.1mSv-1,15 1,11! Good agreement, no need to

Annual doses RF ablations:Low, monitoring not required

Operator Procedure#

proceduresAnnual

dose [mSv]1 RF Abl 180 1.72 RF Abl 60 1.13 RF Abl 100 1.84 RF Abl 70 0.65 RF Abl 100 6.36 RF Abl 65 0.27 RF Abl 160 2.08 RF Abl 210 89 RF Abl 60 4

Page 29: MEASUREMENTS OF EYE LENS DOSES IN ......NIOM SCK Average all 1,91 1,67 2,14 Median all 1,90 1,52 1,07 Average >0.1mSv-1,15 1,18 Median >0.1mSv-1,15 1,11! Good agreement, no need to

However, annual doses both PM&ICD and RF ablations:monitoring required

Operator Procedure # proceduresAnnual dose

[mSv]1 PM&ICD+RF abl 150+60 88+632 PM&ICD+RF abl 190+190 24+133 PM&ICD+RF abl 90+190 25+74 PM&ICD+RF abl 110+50 0.8+1.55 PM&ICD+RF abl 40+20 4+0.16 PM&ICD+RF abl 40+20 7+07 PM&ICD+RF abl 80+350 1+5

Page 30: MEASUREMENTS OF EYE LENS DOSES IN ......NIOM SCK Average all 1,91 1,67 2,14 Median all 1,90 1,52 1,07 Average >0.1mSv-1,15 1,18 Median >0.1mSv-1,15 1,11! Good agreement, no need to

Annual doses:Embolizations and angiographic procedures: often combinations different type of procedures: difficult to estimate:High, monitoring is required

OperatorAnnual dose

[mSv]1 272 233 64 45 156 47 118 31

OperatorAnnual dose

[mSv]9 1410 1011 712 1413 2014 4915 8516 9

Page 31: MEASUREMENTS OF EYE LENS DOSES IN ......NIOM SCK Average all 1,91 1,67 2,14 Median all 1,90 1,52 1,07 Average >0.1mSv-1,15 1,18 Median >0.1mSv-1,15 1,11! Good agreement, no need to

Annual doses:Embolizations and angiagraphic procedures: oneexample

Page 32: MEASUREMENTS OF EYE LENS DOSES IN ......NIOM SCK Average all 1,91 1,67 2,14 Median all 1,90 1,52 1,07 Average >0.1mSv-1,15 1,18 Median >0.1mSv-1,15 1,11! Good agreement, no need to

Conclusiono Measurements of Hp(0.07) in bag gives comparable results with

Hp(3) and eye lens dosemetero Highest doses per procedure found for embolizations

o Around 60 µSv/procedureo Ceiling shield reduces the eye lens doses with

o A factor 3 to 8 for ERCP, embolizationso A factor 1.5 to 2.5 for CA/PTCA, ablations

o Tube below table gives lower eye lens doseso Lead glasses reduce with factor 3 to 6 (simulations)o Doses dependent on work load and protection measures

o Recommended to use ceiling suspended shield and lead glasses

o Monitoring recommended foro All procedureso Except ERCP

o Certainly if dose limit is reduced !!!

Page 33: MEASUREMENTS OF EYE LENS DOSES IN ......NIOM SCK Average all 1,91 1,67 2,14 Median all 1,90 1,52 1,07 Average >0.1mSv-1,15 1,18 Median >0.1mSv-1,15 1,11! Good agreement, no need to

Thank you for you attention!


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