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St Thomas University School of Science, Technology & Engineering Management Medicinal Plants And Cancer Research at STU Wim F.A. Steelant, CE, Ph.D., April 12 th , 2012
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St Thomas UniversitySchool of Science, Technology& Engineering Management
Medicinal PlantsAnd
Cancer Research at STU
Wim F.A. Steelant, CE, Ph.D., April 12th , 2012
Science Building
Carnival Cruise Lines Science & Technology Building
Wim F.A. Steelant, CE, Ph.D., April 12th , 2012
Medicinal Plants
Why medicinal plants & cancer research ???
Wim F.A. Steelant, CE, Ph.D., April 12th , 2012
Medicinal Plants
Ligusticum porteri & Anemopsis californica
Laboratory of Biochemical and Biomedical ResearchCreated in 2004, New Mexico, USA
Biomembrane Structure, Interaction and Signal Transduction
New Medicinal Agents against Diseases
- Native American Medicine man- Ketowa Indian (Cherokee Nation)- Folk medicine with local plants
Wim F.A. Steelant, CE, Ph.D., April 12th , 2012
Importance of Medicinal Plants
• Common names: Loveroot, Porter’s Lovage, Osha,Chuchupate, and Wild Parsley• Location: In the West, Canada to MexicoEspecially the Rocky Mountain region
• Common names: Lizard Tail, Swamp Root, Yerba Mansa
• Common Location: Wet, swampy areas
Medicine man recommended two medicinal plants: Ligusticum porteri (Osha) and Anemopsis californica (Yerba Mansa)
Wim F.A. Steelant, CE, Ph.D., April 12th , 2012
Willow tree Salicin Acetyl-salicylic acid
“Miracle drug”- pain/fever reducer- blood thinner against strokes- acts against cancer- acts against Alzheimer
Importance of Medicinal Plants
Wim F.A. Steelant, CE, Ph.D., April 12th , 2012
Wim F.A. Steelant, CE, Ph.D., April 12th , 2012
Importance of Medicinal Plants
Pacific Yew tree Paclitaxel/Taxol
Used in Cancer Chemotherapy- Discovered in 1967, due to a plant screening by the NCI- In 2000, 1.6 billion US$
Wim F.A. Steelant, CE, Ph.D., April 12th , 2012
Importance of Medicinal Plants
Wim F.A. Steelant, CE, Ph.D., April 12th , 2012
Flower
Leaf
Root
Importance of Medicinal Plants
Wim F.A. Steelant, CE, Ph.D., April 12th , 2012
USDA-FS and STU
Wim F.A. Steelant, CE, Ph.D., April 12th , 2012
Ardesia crenata Pyrus calleryana
Interdisciplinary!
Biological activity testing
AntibacterialAntifungal
Freeze-Dry
Anticancer
Harvest/Voucher specimen
Dried and ground plants
Leafs/roots/flowers
Extraction
Activity
Fractionation
Structure identification
Wim F.A. Steelant, CE, Ph.D., April 12th , 2012
