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by Hafsa and Mehreen Submitted to Mam Huma Alzheimer's desease
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by Hafsa and Mehreen
Submitted to Mam Huma
Alzheimers desease
Alzheimers disease
The Impact of ADOnce considered a rare disorder Alzheimerrsquos disease is now seen as a major public health problem that is seriously affecting millions of older Americans and their families
Slide 2
Alzheimerrsquos disease is an irreversible progressive brain disease that slowly destroys memory and thinking skills
What is AD
Slide 4
1) Early Stage
This is considered as a mildearly stage and the duration period is 2-4 years
Frequent recent memory loss particularly of recent conversations and events
Repeated questions some problems expressing and understanding language
This is considered as a middlemoderate stage the duration is 2-10 years Can no longer cover up problems Pervasive and persistent memory loss impacts
life across settings Rambling speech unusual reasoning
confusion about current events time and place
Nearly 80 of patients exhibit emotional and behavioral problems which are aggravated by stress and change
2) Second stage
Last stage
This is considered as the severe stage the duration is 1-3 years Generally incapacitated with severe to
total loss of verbal skills Unable to care for self Extreme problems with mood behavioral
problems hallucinations and delirium
Neurons
bull The brain has billions of neurons each with an axon and many dendrites
bull To stay healthy neurons must communicate with each other carry out metabolism and repair themselves
bull AD disrupts all three of these essential jobs
Inside the Human Brain
Slide 14
Plaques and Tangles The Hallmarks of AD
The brains of people with AD have an abundance of two abnormal structures
An actual AD plaque An actual AD tangle
bull beta-amyloid plaques which are dense deposits of protein and cellular material that accumulate outside and around nerve cells
bull neurofibrillary tangles which are twisted fibers that build up inside the nerve cell
Slide 16
Beta-amyloid Plaques
Amyloid precursor protein (APP) is the precursor to amyloid plaque
1 APP sticks through the neuron membrane
2 Enzymes cut the APP into fragments of protein including beta-amyloid
3 Beta-amyloid fragments come together in clumps to form plaques
1
2
3
In AD many of these clumps form disrupting the work of neurons This affects the hippocampus and other areas of the cerebral cortex
Slide 17
Neurofibrillary Tangles
Neurons have an internal support structure partly made up of microtubules A protein called tau helps stabilize microtubules In AD tau changes causing microtubules to collapse and tau proteins clump together to form neurofibrillary tangles
AD and the Brain
Slide 18
The Changing Brain in Alzheimerrsquos Disease
No one knows what causes AD to begin but we do know a lot about what happens in the brain once AD takes hold
Pet Scan of Normal Brain
Pet Scan of Alzheimerrsquos Disease Brain
Slide 19
Causes for AD
bull AD develops when genetic lifestyle and environmental factors work together to cause the disease process to start
Slide 24
Genetic Studies
The two main types of AD are early-onset and late-onset
bull Early-onset AD is rare usually affecting people aged 30 to 60 and usually running in families Researchers have identified mutations in three genes that cause early-onset AD
bull Late-onset AD is more common It usually affects people over age 65 Researchers have identified
a gene that produces a protein called apolipoprotein E (ApoE) Scientists believe this protein is involved in the formation of beta-amyloid plaques
Slide 25
Environment and lifestyle factors
Diet ndash Diet can affect a persons risk of developing many types of illness including dementia A healthy and balanced diet that enables a person to maintain a normal body weight is likely to reduce the likelihood of developing high blood pressure or heart disease both of which put a person at greater risk of developing dementia
Smoking ndash Smoking has an extremely harmful effect on the heart lungs and vascular system including the blood vessels in the brain This significantly increases the risk of developing dementia
Alcohol ndash Drinking above recommended levels of alcohol significantly increases the risk of developing dementias such as Alzheimers and vascular dementia However research suggests that light-to-moderate amounts of alcohol may protect the brain against dementia and keep the heart and vascular system healthy
Social activity ndash Research suggests that people who are more socially active have a slightly reduced risk of developing dementia
Mental activity ndash Research suggests that people who take part in mental activities (such as reading learning and doing puzzles) are less likely to develop dementia compared with those who do not engage in these activities
Continuedhelliphelliphelliphelliphelliphellip
Diagnosing for AD
Diagnosing AD
Experienced physicians in specialized AD centers can now diagnose AD with up to 90 percent accuracy Early diagnosis has advantages
bull Doctors can rule out other conditions that may cause dementia
bull If it is AD families have more time to plan for the future
bull Treatments can start earlier when they may be more effective
bull It helps scientists learn more about the causes and development of AD
Slide 29
Physicians today use a number of tools to diagnose AD
bull a detailed patient history
bull information from family and friends
bull physical and neurological exams and lab tests
bull neuropsychological tests
bull imaging tools such as CT scan or magnetic resonance imaging (MRI) PET scans are used primarily for research purposes
CONTINUEDhelliphelliphelliphelliphelliphellip
Slide 30
Clinical trials are the primary way that researchers find out if a promising treatment is safe and effective
bull Trials examine approved drugs to see if they can be used for other purposes or look at experimental drugs
bull Participating in a trial means regular contact with the study team who can provide state-of-the-art AD care
Clinical Trials
Slide 31
Drugs used to treat mild to moderate AD symptoms include
bull Aricept
bull Exelon
bull Reminyl
An additional drug Namenda has been approved to treat symptoms of moderate to severe AD These drugs can help improve some patientsrsquo abilities to carry out activities up to a year or so but they do not stop or reverse AD
Scientists are also studying agents that someday may be useful in preventing AD For example they have experimented with a vaccine against AD Although the first clinical trial was stopped due to side effects in some participants valuable information was gathered
Treatments for AD
Slide 32
Researchers also are looking at other treatments including
bull cholesterol-lowering drugs called statins
bull anti-oxidants (vitamins) and folic acid
bull anti-inflammatory drugs
bull substances that prevent formation of beta-amyloid plaques
bull nerve growth factor to keep neurons healthy
Search for New Treatments
Slide 33
Who are the AD Caregiversbull Spouses ndash the largest group Most are older with
their own health problemsbull Daughters ndash the second largest group Called the
ldquosandwich generationrdquo many are married and raising children of their own Children may need extra support if a parentrsquos attention is focused on care giving
bull Grandchildren ndash may become major helpers
bull Daughters-in-law ndash the third largest group bull Sons ndash often focus on the financial legal and
business aspects of care giving bull Brothers and Sisters ndash many are older with
their own health problemsbull Other ndash friends neighbors members of the
faith community
Support for Caregivers
Slide 37
The NIA is studying how computers can provide information and support to family caregivers through
These features have become very popular among users because they reach many people at once are private and convenient and are available around the clock
bull computer-based bulletin boardsbull chat roomsbull Q amp A modulesbull medical advice forums
Slide 39
Technology and Care giving
One of the great mysteries of Alzheimerrsquos disease is why it largely strikes older adults
Research on how the brain changes normally with age is shedding light on this question For example scientists are learning how age-related changes in the brain may harm neurons and contribute to Alzheimerrsquos damage These age-related changes include atrophy (shrinking) of certain parts of the brain inflammation the production of unstable molecules called free radicals and mitochondrial dysfunction (a breakdown of energy production within a cell)
bull Generally it is diagnosed in people over 65 years of age although the less-prevalent early onset of Alzheimerrsquos can occur much earlier
bull In 2006 there were 266 million sufferers worldwide
bull Alzheimerrsquos is predicted to affect 1 in 85 people globally by 2050
Signs Of Normal Change vs Early Alzheimerrsquos Symptoms
Normal Early Alzheimerrsquos Disease
Canrsquot find your keys Routinely place important items in odd places such as keys in the fridge wallet in the dishwasher
Search for casual names and words
Forget names of family members and common objects or substitute words with inappropriate ones
Briefly forget conversation details
Frequently forget entire conversations
Feel the cold more Dress regardless of the weather wear several skirts on a warm day or shorts in a snow storm
Canrsquot find a recipe Canrsquot follow recipe directions
Forget to record a check Can no longer manage checkbook balance figures solve problems or think abstractly
Cancel a date with friends Withdraw from usual interests and activities sit in front of the TV for hours sleep far more than usual
Make an occasional wrong turn
Get lost in familiar places donrsquot remember how you got there or how to get home
Feel occasionally sad Experience rapid mood swings from tears to rage for no discernible reason
Life expectancyOn average people with Alzheimers disease live for around 8 to 10 years after they start to develop symptoms However this can vary considerably from person to person Some people with the condition will live longer than this but others will not
Alzheimers disease is not usually the actual cause of death but it is often a contributing factor For example a leading cause of death in people with Alzheimers disease is pneumonia (lung infection) which may go untreated because people with the condition often arent able to recognize that theyre ill or may not be able to tell someone they are feeling unwell
RESULTS 1203 subjects were resurveyed in 1997 and among them 124 new cases of dementia including 81 cases of AD were identified By computing the relative risk(RR) of psychosocial factors to the AD many psychosocial factors were found to be correlated with AD including blue collar occupation no job no reading or writing no taking community activities no gardening in leisure bad psychological feeling and lower education (RR gt 1) The items with high PARP gt 50 were not working no job retirement no taking community activities no reading or writing blue collar occupation and no gardening in leisure MMSE total score is a good predict for AD
Psychosocial risk factors of Alzheimers disease
Too much cake and chocolate could cause Alzheimers disease new research claims
Risk The study adds further evidence to links between diabetes and dementia
Eating too many chocolates cakes and other sugary treats could help trigger Alzheimerrsquos disease says new research
bullA study in mice found high levels of blood sugar rapidly increased rogue proteins in the body which combine and kill brain cells ultimately leading to dementia
CONTINUEDhelliphelliphelliphelliphellip
Green tea has also been proven to have beneficial effects when it comes to
Alzheimers(ALAMY)
Some famous books on Alzheimers
The 36-Hour Day fifth edition The 36-Hour by Nancy L Mace
Learning to Speak Alzheimers A Groundbrea
by Joanne Koenig Coste
The Validation Breakthrough Third Edition by Naomi Feil MSW
Alzheimers Disease What If There Was a Cu by Mary T Newport
A Caregivers Guide to Alzheimers Disease by Patricia R Callone
Creating Moments of Joy for the Person with by Jolene Brackey
Alzheimers Early Stages First Steps for F by Daniel Kuhn
Alzheimers Disease and Other Dementias - T by Nataly Rubinstein
Alzheimers For Dummies by Patricia B Smith
Some famous person died of Alzheimers
Fantasy author Sir Terry Pratchett dies at 66
Sir Terry Pratchett renowned fantasy author of more than 70 books has died at age 66
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Alzheimers disease
The Impact of ADOnce considered a rare disorder Alzheimerrsquos disease is now seen as a major public health problem that is seriously affecting millions of older Americans and their families
Slide 2
Alzheimerrsquos disease is an irreversible progressive brain disease that slowly destroys memory and thinking skills
What is AD
Slide 4
1) Early Stage
This is considered as a mildearly stage and the duration period is 2-4 years
Frequent recent memory loss particularly of recent conversations and events
Repeated questions some problems expressing and understanding language
This is considered as a middlemoderate stage the duration is 2-10 years Can no longer cover up problems Pervasive and persistent memory loss impacts
life across settings Rambling speech unusual reasoning
confusion about current events time and place
Nearly 80 of patients exhibit emotional and behavioral problems which are aggravated by stress and change
2) Second stage
Last stage
This is considered as the severe stage the duration is 1-3 years Generally incapacitated with severe to
total loss of verbal skills Unable to care for self Extreme problems with mood behavioral
problems hallucinations and delirium
Neurons
bull The brain has billions of neurons each with an axon and many dendrites
bull To stay healthy neurons must communicate with each other carry out metabolism and repair themselves
bull AD disrupts all three of these essential jobs
Inside the Human Brain
Slide 14
Plaques and Tangles The Hallmarks of AD
The brains of people with AD have an abundance of two abnormal structures
An actual AD plaque An actual AD tangle
bull beta-amyloid plaques which are dense deposits of protein and cellular material that accumulate outside and around nerve cells
bull neurofibrillary tangles which are twisted fibers that build up inside the nerve cell
Slide 16
Beta-amyloid Plaques
Amyloid precursor protein (APP) is the precursor to amyloid plaque
1 APP sticks through the neuron membrane
2 Enzymes cut the APP into fragments of protein including beta-amyloid
3 Beta-amyloid fragments come together in clumps to form plaques
1
2
3
In AD many of these clumps form disrupting the work of neurons This affects the hippocampus and other areas of the cerebral cortex
Slide 17
Neurofibrillary Tangles
Neurons have an internal support structure partly made up of microtubules A protein called tau helps stabilize microtubules In AD tau changes causing microtubules to collapse and tau proteins clump together to form neurofibrillary tangles
AD and the Brain
Slide 18
The Changing Brain in Alzheimerrsquos Disease
No one knows what causes AD to begin but we do know a lot about what happens in the brain once AD takes hold
Pet Scan of Normal Brain
Pet Scan of Alzheimerrsquos Disease Brain
Slide 19
Causes for AD
bull AD develops when genetic lifestyle and environmental factors work together to cause the disease process to start
Slide 24
Genetic Studies
The two main types of AD are early-onset and late-onset
bull Early-onset AD is rare usually affecting people aged 30 to 60 and usually running in families Researchers have identified mutations in three genes that cause early-onset AD
bull Late-onset AD is more common It usually affects people over age 65 Researchers have identified
a gene that produces a protein called apolipoprotein E (ApoE) Scientists believe this protein is involved in the formation of beta-amyloid plaques
Slide 25
Environment and lifestyle factors
Diet ndash Diet can affect a persons risk of developing many types of illness including dementia A healthy and balanced diet that enables a person to maintain a normal body weight is likely to reduce the likelihood of developing high blood pressure or heart disease both of which put a person at greater risk of developing dementia
Smoking ndash Smoking has an extremely harmful effect on the heart lungs and vascular system including the blood vessels in the brain This significantly increases the risk of developing dementia
Alcohol ndash Drinking above recommended levels of alcohol significantly increases the risk of developing dementias such as Alzheimers and vascular dementia However research suggests that light-to-moderate amounts of alcohol may protect the brain against dementia and keep the heart and vascular system healthy
Social activity ndash Research suggests that people who are more socially active have a slightly reduced risk of developing dementia
Mental activity ndash Research suggests that people who take part in mental activities (such as reading learning and doing puzzles) are less likely to develop dementia compared with those who do not engage in these activities
Continuedhelliphelliphelliphelliphelliphellip
Diagnosing for AD
Diagnosing AD
Experienced physicians in specialized AD centers can now diagnose AD with up to 90 percent accuracy Early diagnosis has advantages
bull Doctors can rule out other conditions that may cause dementia
bull If it is AD families have more time to plan for the future
bull Treatments can start earlier when they may be more effective
bull It helps scientists learn more about the causes and development of AD
Slide 29
Physicians today use a number of tools to diagnose AD
bull a detailed patient history
bull information from family and friends
bull physical and neurological exams and lab tests
bull neuropsychological tests
bull imaging tools such as CT scan or magnetic resonance imaging (MRI) PET scans are used primarily for research purposes
CONTINUEDhelliphelliphelliphelliphelliphellip
Slide 30
Clinical trials are the primary way that researchers find out if a promising treatment is safe and effective
bull Trials examine approved drugs to see if they can be used for other purposes or look at experimental drugs
bull Participating in a trial means regular contact with the study team who can provide state-of-the-art AD care
Clinical Trials
Slide 31
Drugs used to treat mild to moderate AD symptoms include
bull Aricept
bull Exelon
bull Reminyl
An additional drug Namenda has been approved to treat symptoms of moderate to severe AD These drugs can help improve some patientsrsquo abilities to carry out activities up to a year or so but they do not stop or reverse AD
Scientists are also studying agents that someday may be useful in preventing AD For example they have experimented with a vaccine against AD Although the first clinical trial was stopped due to side effects in some participants valuable information was gathered
Treatments for AD
Slide 32
Researchers also are looking at other treatments including
bull cholesterol-lowering drugs called statins
bull anti-oxidants (vitamins) and folic acid
bull anti-inflammatory drugs
bull substances that prevent formation of beta-amyloid plaques
bull nerve growth factor to keep neurons healthy
Search for New Treatments
Slide 33
Who are the AD Caregiversbull Spouses ndash the largest group Most are older with
their own health problemsbull Daughters ndash the second largest group Called the
ldquosandwich generationrdquo many are married and raising children of their own Children may need extra support if a parentrsquos attention is focused on care giving
bull Grandchildren ndash may become major helpers
bull Daughters-in-law ndash the third largest group bull Sons ndash often focus on the financial legal and
business aspects of care giving bull Brothers and Sisters ndash many are older with
their own health problemsbull Other ndash friends neighbors members of the
faith community
Support for Caregivers
Slide 37
The NIA is studying how computers can provide information and support to family caregivers through
These features have become very popular among users because they reach many people at once are private and convenient and are available around the clock
bull computer-based bulletin boardsbull chat roomsbull Q amp A modulesbull medical advice forums
Slide 39
Technology and Care giving
One of the great mysteries of Alzheimerrsquos disease is why it largely strikes older adults
Research on how the brain changes normally with age is shedding light on this question For example scientists are learning how age-related changes in the brain may harm neurons and contribute to Alzheimerrsquos damage These age-related changes include atrophy (shrinking) of certain parts of the brain inflammation the production of unstable molecules called free radicals and mitochondrial dysfunction (a breakdown of energy production within a cell)
bull Generally it is diagnosed in people over 65 years of age although the less-prevalent early onset of Alzheimerrsquos can occur much earlier
bull In 2006 there were 266 million sufferers worldwide
bull Alzheimerrsquos is predicted to affect 1 in 85 people globally by 2050
Signs Of Normal Change vs Early Alzheimerrsquos Symptoms
Normal Early Alzheimerrsquos Disease
Canrsquot find your keys Routinely place important items in odd places such as keys in the fridge wallet in the dishwasher
Search for casual names and words
Forget names of family members and common objects or substitute words with inappropriate ones
Briefly forget conversation details
Frequently forget entire conversations
Feel the cold more Dress regardless of the weather wear several skirts on a warm day or shorts in a snow storm
Canrsquot find a recipe Canrsquot follow recipe directions
Forget to record a check Can no longer manage checkbook balance figures solve problems or think abstractly
Cancel a date with friends Withdraw from usual interests and activities sit in front of the TV for hours sleep far more than usual
Make an occasional wrong turn
Get lost in familiar places donrsquot remember how you got there or how to get home
Feel occasionally sad Experience rapid mood swings from tears to rage for no discernible reason
Life expectancyOn average people with Alzheimers disease live for around 8 to 10 years after they start to develop symptoms However this can vary considerably from person to person Some people with the condition will live longer than this but others will not
Alzheimers disease is not usually the actual cause of death but it is often a contributing factor For example a leading cause of death in people with Alzheimers disease is pneumonia (lung infection) which may go untreated because people with the condition often arent able to recognize that theyre ill or may not be able to tell someone they are feeling unwell
RESULTS 1203 subjects were resurveyed in 1997 and among them 124 new cases of dementia including 81 cases of AD were identified By computing the relative risk(RR) of psychosocial factors to the AD many psychosocial factors were found to be correlated with AD including blue collar occupation no job no reading or writing no taking community activities no gardening in leisure bad psychological feeling and lower education (RR gt 1) The items with high PARP gt 50 were not working no job retirement no taking community activities no reading or writing blue collar occupation and no gardening in leisure MMSE total score is a good predict for AD
Psychosocial risk factors of Alzheimers disease
Too much cake and chocolate could cause Alzheimers disease new research claims
Risk The study adds further evidence to links between diabetes and dementia
Eating too many chocolates cakes and other sugary treats could help trigger Alzheimerrsquos disease says new research
bullA study in mice found high levels of blood sugar rapidly increased rogue proteins in the body which combine and kill brain cells ultimately leading to dementia
CONTINUEDhelliphelliphelliphelliphellip
Green tea has also been proven to have beneficial effects when it comes to
Alzheimers(ALAMY)
Some famous books on Alzheimers
The 36-Hour Day fifth edition The 36-Hour by Nancy L Mace
Learning to Speak Alzheimers A Groundbrea
by Joanne Koenig Coste
The Validation Breakthrough Third Edition by Naomi Feil MSW
Alzheimers Disease What If There Was a Cu by Mary T Newport
A Caregivers Guide to Alzheimers Disease by Patricia R Callone
Creating Moments of Joy for the Person with by Jolene Brackey
Alzheimers Early Stages First Steps for F by Daniel Kuhn
Alzheimers Disease and Other Dementias - T by Nataly Rubinstein
Alzheimers For Dummies by Patricia B Smith
Some famous person died of Alzheimers
Fantasy author Sir Terry Pratchett dies at 66
Sir Terry Pratchett renowned fantasy author of more than 70 books has died at age 66
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
The Impact of ADOnce considered a rare disorder Alzheimerrsquos disease is now seen as a major public health problem that is seriously affecting millions of older Americans and their families
Slide 2
Alzheimerrsquos disease is an irreversible progressive brain disease that slowly destroys memory and thinking skills
What is AD
Slide 4
1) Early Stage
This is considered as a mildearly stage and the duration period is 2-4 years
Frequent recent memory loss particularly of recent conversations and events
Repeated questions some problems expressing and understanding language
This is considered as a middlemoderate stage the duration is 2-10 years Can no longer cover up problems Pervasive and persistent memory loss impacts
life across settings Rambling speech unusual reasoning
confusion about current events time and place
Nearly 80 of patients exhibit emotional and behavioral problems which are aggravated by stress and change
2) Second stage
Last stage
This is considered as the severe stage the duration is 1-3 years Generally incapacitated with severe to
total loss of verbal skills Unable to care for self Extreme problems with mood behavioral
problems hallucinations and delirium
Neurons
bull The brain has billions of neurons each with an axon and many dendrites
bull To stay healthy neurons must communicate with each other carry out metabolism and repair themselves
bull AD disrupts all three of these essential jobs
Inside the Human Brain
Slide 14
Plaques and Tangles The Hallmarks of AD
The brains of people with AD have an abundance of two abnormal structures
An actual AD plaque An actual AD tangle
bull beta-amyloid plaques which are dense deposits of protein and cellular material that accumulate outside and around nerve cells
bull neurofibrillary tangles which are twisted fibers that build up inside the nerve cell
Slide 16
Beta-amyloid Plaques
Amyloid precursor protein (APP) is the precursor to amyloid plaque
1 APP sticks through the neuron membrane
2 Enzymes cut the APP into fragments of protein including beta-amyloid
3 Beta-amyloid fragments come together in clumps to form plaques
1
2
3
In AD many of these clumps form disrupting the work of neurons This affects the hippocampus and other areas of the cerebral cortex
Slide 17
Neurofibrillary Tangles
Neurons have an internal support structure partly made up of microtubules A protein called tau helps stabilize microtubules In AD tau changes causing microtubules to collapse and tau proteins clump together to form neurofibrillary tangles
AD and the Brain
Slide 18
The Changing Brain in Alzheimerrsquos Disease
No one knows what causes AD to begin but we do know a lot about what happens in the brain once AD takes hold
Pet Scan of Normal Brain
Pet Scan of Alzheimerrsquos Disease Brain
Slide 19
Causes for AD
bull AD develops when genetic lifestyle and environmental factors work together to cause the disease process to start
Slide 24
Genetic Studies
The two main types of AD are early-onset and late-onset
bull Early-onset AD is rare usually affecting people aged 30 to 60 and usually running in families Researchers have identified mutations in three genes that cause early-onset AD
bull Late-onset AD is more common It usually affects people over age 65 Researchers have identified
a gene that produces a protein called apolipoprotein E (ApoE) Scientists believe this protein is involved in the formation of beta-amyloid plaques
Slide 25
Environment and lifestyle factors
Diet ndash Diet can affect a persons risk of developing many types of illness including dementia A healthy and balanced diet that enables a person to maintain a normal body weight is likely to reduce the likelihood of developing high blood pressure or heart disease both of which put a person at greater risk of developing dementia
Smoking ndash Smoking has an extremely harmful effect on the heart lungs and vascular system including the blood vessels in the brain This significantly increases the risk of developing dementia
Alcohol ndash Drinking above recommended levels of alcohol significantly increases the risk of developing dementias such as Alzheimers and vascular dementia However research suggests that light-to-moderate amounts of alcohol may protect the brain against dementia and keep the heart and vascular system healthy
Social activity ndash Research suggests that people who are more socially active have a slightly reduced risk of developing dementia
Mental activity ndash Research suggests that people who take part in mental activities (such as reading learning and doing puzzles) are less likely to develop dementia compared with those who do not engage in these activities
Continuedhelliphelliphelliphelliphelliphellip
Diagnosing for AD
Diagnosing AD
Experienced physicians in specialized AD centers can now diagnose AD with up to 90 percent accuracy Early diagnosis has advantages
bull Doctors can rule out other conditions that may cause dementia
bull If it is AD families have more time to plan for the future
bull Treatments can start earlier when they may be more effective
bull It helps scientists learn more about the causes and development of AD
Slide 29
Physicians today use a number of tools to diagnose AD
bull a detailed patient history
bull information from family and friends
bull physical and neurological exams and lab tests
bull neuropsychological tests
bull imaging tools such as CT scan or magnetic resonance imaging (MRI) PET scans are used primarily for research purposes
CONTINUEDhelliphelliphelliphelliphelliphellip
Slide 30
Clinical trials are the primary way that researchers find out if a promising treatment is safe and effective
bull Trials examine approved drugs to see if they can be used for other purposes or look at experimental drugs
bull Participating in a trial means regular contact with the study team who can provide state-of-the-art AD care
Clinical Trials
Slide 31
Drugs used to treat mild to moderate AD symptoms include
bull Aricept
bull Exelon
bull Reminyl
An additional drug Namenda has been approved to treat symptoms of moderate to severe AD These drugs can help improve some patientsrsquo abilities to carry out activities up to a year or so but they do not stop or reverse AD
Scientists are also studying agents that someday may be useful in preventing AD For example they have experimented with a vaccine against AD Although the first clinical trial was stopped due to side effects in some participants valuable information was gathered
Treatments for AD
Slide 32
Researchers also are looking at other treatments including
bull cholesterol-lowering drugs called statins
bull anti-oxidants (vitamins) and folic acid
bull anti-inflammatory drugs
bull substances that prevent formation of beta-amyloid plaques
bull nerve growth factor to keep neurons healthy
Search for New Treatments
Slide 33
Who are the AD Caregiversbull Spouses ndash the largest group Most are older with
their own health problemsbull Daughters ndash the second largest group Called the
ldquosandwich generationrdquo many are married and raising children of their own Children may need extra support if a parentrsquos attention is focused on care giving
bull Grandchildren ndash may become major helpers
bull Daughters-in-law ndash the third largest group bull Sons ndash often focus on the financial legal and
business aspects of care giving bull Brothers and Sisters ndash many are older with
their own health problemsbull Other ndash friends neighbors members of the
faith community
Support for Caregivers
Slide 37
The NIA is studying how computers can provide information and support to family caregivers through
These features have become very popular among users because they reach many people at once are private and convenient and are available around the clock
bull computer-based bulletin boardsbull chat roomsbull Q amp A modulesbull medical advice forums
Slide 39
Technology and Care giving
One of the great mysteries of Alzheimerrsquos disease is why it largely strikes older adults
Research on how the brain changes normally with age is shedding light on this question For example scientists are learning how age-related changes in the brain may harm neurons and contribute to Alzheimerrsquos damage These age-related changes include atrophy (shrinking) of certain parts of the brain inflammation the production of unstable molecules called free radicals and mitochondrial dysfunction (a breakdown of energy production within a cell)
bull Generally it is diagnosed in people over 65 years of age although the less-prevalent early onset of Alzheimerrsquos can occur much earlier
bull In 2006 there were 266 million sufferers worldwide
bull Alzheimerrsquos is predicted to affect 1 in 85 people globally by 2050
Signs Of Normal Change vs Early Alzheimerrsquos Symptoms
Normal Early Alzheimerrsquos Disease
Canrsquot find your keys Routinely place important items in odd places such as keys in the fridge wallet in the dishwasher
Search for casual names and words
Forget names of family members and common objects or substitute words with inappropriate ones
Briefly forget conversation details
Frequently forget entire conversations
Feel the cold more Dress regardless of the weather wear several skirts on a warm day or shorts in a snow storm
Canrsquot find a recipe Canrsquot follow recipe directions
Forget to record a check Can no longer manage checkbook balance figures solve problems or think abstractly
Cancel a date with friends Withdraw from usual interests and activities sit in front of the TV for hours sleep far more than usual
Make an occasional wrong turn
Get lost in familiar places donrsquot remember how you got there or how to get home
Feel occasionally sad Experience rapid mood swings from tears to rage for no discernible reason
Life expectancyOn average people with Alzheimers disease live for around 8 to 10 years after they start to develop symptoms However this can vary considerably from person to person Some people with the condition will live longer than this but others will not
Alzheimers disease is not usually the actual cause of death but it is often a contributing factor For example a leading cause of death in people with Alzheimers disease is pneumonia (lung infection) which may go untreated because people with the condition often arent able to recognize that theyre ill or may not be able to tell someone they are feeling unwell
RESULTS 1203 subjects were resurveyed in 1997 and among them 124 new cases of dementia including 81 cases of AD were identified By computing the relative risk(RR) of psychosocial factors to the AD many psychosocial factors were found to be correlated with AD including blue collar occupation no job no reading or writing no taking community activities no gardening in leisure bad psychological feeling and lower education (RR gt 1) The items with high PARP gt 50 were not working no job retirement no taking community activities no reading or writing blue collar occupation and no gardening in leisure MMSE total score is a good predict for AD
Psychosocial risk factors of Alzheimers disease
Too much cake and chocolate could cause Alzheimers disease new research claims
Risk The study adds further evidence to links between diabetes and dementia
Eating too many chocolates cakes and other sugary treats could help trigger Alzheimerrsquos disease says new research
bullA study in mice found high levels of blood sugar rapidly increased rogue proteins in the body which combine and kill brain cells ultimately leading to dementia
CONTINUEDhelliphelliphelliphelliphellip
Green tea has also been proven to have beneficial effects when it comes to
Alzheimers(ALAMY)
Some famous books on Alzheimers
The 36-Hour Day fifth edition The 36-Hour by Nancy L Mace
Learning to Speak Alzheimers A Groundbrea
by Joanne Koenig Coste
The Validation Breakthrough Third Edition by Naomi Feil MSW
Alzheimers Disease What If There Was a Cu by Mary T Newport
A Caregivers Guide to Alzheimers Disease by Patricia R Callone
Creating Moments of Joy for the Person with by Jolene Brackey
Alzheimers Early Stages First Steps for F by Daniel Kuhn
Alzheimers Disease and Other Dementias - T by Nataly Rubinstein
Alzheimers For Dummies by Patricia B Smith
Some famous person died of Alzheimers
Fantasy author Sir Terry Pratchett dies at 66
Sir Terry Pratchett renowned fantasy author of more than 70 books has died at age 66
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Alzheimerrsquos disease is an irreversible progressive brain disease that slowly destroys memory and thinking skills
What is AD
Slide 4
1) Early Stage
This is considered as a mildearly stage and the duration period is 2-4 years
Frequent recent memory loss particularly of recent conversations and events
Repeated questions some problems expressing and understanding language
This is considered as a middlemoderate stage the duration is 2-10 years Can no longer cover up problems Pervasive and persistent memory loss impacts
life across settings Rambling speech unusual reasoning
confusion about current events time and place
Nearly 80 of patients exhibit emotional and behavioral problems which are aggravated by stress and change
2) Second stage
Last stage
This is considered as the severe stage the duration is 1-3 years Generally incapacitated with severe to
total loss of verbal skills Unable to care for self Extreme problems with mood behavioral
problems hallucinations and delirium
Neurons
bull The brain has billions of neurons each with an axon and many dendrites
bull To stay healthy neurons must communicate with each other carry out metabolism and repair themselves
bull AD disrupts all three of these essential jobs
Inside the Human Brain
Slide 14
Plaques and Tangles The Hallmarks of AD
The brains of people with AD have an abundance of two abnormal structures
An actual AD plaque An actual AD tangle
bull beta-amyloid plaques which are dense deposits of protein and cellular material that accumulate outside and around nerve cells
bull neurofibrillary tangles which are twisted fibers that build up inside the nerve cell
Slide 16
Beta-amyloid Plaques
Amyloid precursor protein (APP) is the precursor to amyloid plaque
1 APP sticks through the neuron membrane
2 Enzymes cut the APP into fragments of protein including beta-amyloid
3 Beta-amyloid fragments come together in clumps to form plaques
1
2
3
In AD many of these clumps form disrupting the work of neurons This affects the hippocampus and other areas of the cerebral cortex
Slide 17
Neurofibrillary Tangles
Neurons have an internal support structure partly made up of microtubules A protein called tau helps stabilize microtubules In AD tau changes causing microtubules to collapse and tau proteins clump together to form neurofibrillary tangles
AD and the Brain
Slide 18
The Changing Brain in Alzheimerrsquos Disease
No one knows what causes AD to begin but we do know a lot about what happens in the brain once AD takes hold
Pet Scan of Normal Brain
Pet Scan of Alzheimerrsquos Disease Brain
Slide 19
Causes for AD
bull AD develops when genetic lifestyle and environmental factors work together to cause the disease process to start
Slide 24
Genetic Studies
The two main types of AD are early-onset and late-onset
bull Early-onset AD is rare usually affecting people aged 30 to 60 and usually running in families Researchers have identified mutations in three genes that cause early-onset AD
bull Late-onset AD is more common It usually affects people over age 65 Researchers have identified
a gene that produces a protein called apolipoprotein E (ApoE) Scientists believe this protein is involved in the formation of beta-amyloid plaques
Slide 25
Environment and lifestyle factors
Diet ndash Diet can affect a persons risk of developing many types of illness including dementia A healthy and balanced diet that enables a person to maintain a normal body weight is likely to reduce the likelihood of developing high blood pressure or heart disease both of which put a person at greater risk of developing dementia
Smoking ndash Smoking has an extremely harmful effect on the heart lungs and vascular system including the blood vessels in the brain This significantly increases the risk of developing dementia
Alcohol ndash Drinking above recommended levels of alcohol significantly increases the risk of developing dementias such as Alzheimers and vascular dementia However research suggests that light-to-moderate amounts of alcohol may protect the brain against dementia and keep the heart and vascular system healthy
Social activity ndash Research suggests that people who are more socially active have a slightly reduced risk of developing dementia
Mental activity ndash Research suggests that people who take part in mental activities (such as reading learning and doing puzzles) are less likely to develop dementia compared with those who do not engage in these activities
Continuedhelliphelliphelliphelliphelliphellip
Diagnosing for AD
Diagnosing AD
Experienced physicians in specialized AD centers can now diagnose AD with up to 90 percent accuracy Early diagnosis has advantages
bull Doctors can rule out other conditions that may cause dementia
bull If it is AD families have more time to plan for the future
bull Treatments can start earlier when they may be more effective
bull It helps scientists learn more about the causes and development of AD
Slide 29
Physicians today use a number of tools to diagnose AD
bull a detailed patient history
bull information from family and friends
bull physical and neurological exams and lab tests
bull neuropsychological tests
bull imaging tools such as CT scan or magnetic resonance imaging (MRI) PET scans are used primarily for research purposes
CONTINUEDhelliphelliphelliphelliphelliphellip
Slide 30
Clinical trials are the primary way that researchers find out if a promising treatment is safe and effective
bull Trials examine approved drugs to see if they can be used for other purposes or look at experimental drugs
bull Participating in a trial means regular contact with the study team who can provide state-of-the-art AD care
Clinical Trials
Slide 31
Drugs used to treat mild to moderate AD symptoms include
bull Aricept
bull Exelon
bull Reminyl
An additional drug Namenda has been approved to treat symptoms of moderate to severe AD These drugs can help improve some patientsrsquo abilities to carry out activities up to a year or so but they do not stop or reverse AD
Scientists are also studying agents that someday may be useful in preventing AD For example they have experimented with a vaccine against AD Although the first clinical trial was stopped due to side effects in some participants valuable information was gathered
Treatments for AD
Slide 32
Researchers also are looking at other treatments including
bull cholesterol-lowering drugs called statins
bull anti-oxidants (vitamins) and folic acid
bull anti-inflammatory drugs
bull substances that prevent formation of beta-amyloid plaques
bull nerve growth factor to keep neurons healthy
Search for New Treatments
Slide 33
Who are the AD Caregiversbull Spouses ndash the largest group Most are older with
their own health problemsbull Daughters ndash the second largest group Called the
ldquosandwich generationrdquo many are married and raising children of their own Children may need extra support if a parentrsquos attention is focused on care giving
bull Grandchildren ndash may become major helpers
bull Daughters-in-law ndash the third largest group bull Sons ndash often focus on the financial legal and
business aspects of care giving bull Brothers and Sisters ndash many are older with
their own health problemsbull Other ndash friends neighbors members of the
faith community
Support for Caregivers
Slide 37
The NIA is studying how computers can provide information and support to family caregivers through
These features have become very popular among users because they reach many people at once are private and convenient and are available around the clock
bull computer-based bulletin boardsbull chat roomsbull Q amp A modulesbull medical advice forums
Slide 39
Technology and Care giving
One of the great mysteries of Alzheimerrsquos disease is why it largely strikes older adults
Research on how the brain changes normally with age is shedding light on this question For example scientists are learning how age-related changes in the brain may harm neurons and contribute to Alzheimerrsquos damage These age-related changes include atrophy (shrinking) of certain parts of the brain inflammation the production of unstable molecules called free radicals and mitochondrial dysfunction (a breakdown of energy production within a cell)
bull Generally it is diagnosed in people over 65 years of age although the less-prevalent early onset of Alzheimerrsquos can occur much earlier
bull In 2006 there were 266 million sufferers worldwide
bull Alzheimerrsquos is predicted to affect 1 in 85 people globally by 2050
Signs Of Normal Change vs Early Alzheimerrsquos Symptoms
Normal Early Alzheimerrsquos Disease
Canrsquot find your keys Routinely place important items in odd places such as keys in the fridge wallet in the dishwasher
Search for casual names and words
Forget names of family members and common objects or substitute words with inappropriate ones
Briefly forget conversation details
Frequently forget entire conversations
Feel the cold more Dress regardless of the weather wear several skirts on a warm day or shorts in a snow storm
Canrsquot find a recipe Canrsquot follow recipe directions
Forget to record a check Can no longer manage checkbook balance figures solve problems or think abstractly
Cancel a date with friends Withdraw from usual interests and activities sit in front of the TV for hours sleep far more than usual
Make an occasional wrong turn
Get lost in familiar places donrsquot remember how you got there or how to get home
Feel occasionally sad Experience rapid mood swings from tears to rage for no discernible reason
Life expectancyOn average people with Alzheimers disease live for around 8 to 10 years after they start to develop symptoms However this can vary considerably from person to person Some people with the condition will live longer than this but others will not
Alzheimers disease is not usually the actual cause of death but it is often a contributing factor For example a leading cause of death in people with Alzheimers disease is pneumonia (lung infection) which may go untreated because people with the condition often arent able to recognize that theyre ill or may not be able to tell someone they are feeling unwell
RESULTS 1203 subjects were resurveyed in 1997 and among them 124 new cases of dementia including 81 cases of AD were identified By computing the relative risk(RR) of psychosocial factors to the AD many psychosocial factors were found to be correlated with AD including blue collar occupation no job no reading or writing no taking community activities no gardening in leisure bad psychological feeling and lower education (RR gt 1) The items with high PARP gt 50 were not working no job retirement no taking community activities no reading or writing blue collar occupation and no gardening in leisure MMSE total score is a good predict for AD
Psychosocial risk factors of Alzheimers disease
Too much cake and chocolate could cause Alzheimers disease new research claims
Risk The study adds further evidence to links between diabetes and dementia
Eating too many chocolates cakes and other sugary treats could help trigger Alzheimerrsquos disease says new research
bullA study in mice found high levels of blood sugar rapidly increased rogue proteins in the body which combine and kill brain cells ultimately leading to dementia
CONTINUEDhelliphelliphelliphelliphellip
Green tea has also been proven to have beneficial effects when it comes to
Alzheimers(ALAMY)
Some famous books on Alzheimers
The 36-Hour Day fifth edition The 36-Hour by Nancy L Mace
Learning to Speak Alzheimers A Groundbrea
by Joanne Koenig Coste
The Validation Breakthrough Third Edition by Naomi Feil MSW
Alzheimers Disease What If There Was a Cu by Mary T Newport
A Caregivers Guide to Alzheimers Disease by Patricia R Callone
Creating Moments of Joy for the Person with by Jolene Brackey
Alzheimers Early Stages First Steps for F by Daniel Kuhn
Alzheimers Disease and Other Dementias - T by Nataly Rubinstein
Alzheimers For Dummies by Patricia B Smith
Some famous person died of Alzheimers
Fantasy author Sir Terry Pratchett dies at 66
Sir Terry Pratchett renowned fantasy author of more than 70 books has died at age 66
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
1) Early Stage
This is considered as a mildearly stage and the duration period is 2-4 years
Frequent recent memory loss particularly of recent conversations and events
Repeated questions some problems expressing and understanding language
This is considered as a middlemoderate stage the duration is 2-10 years Can no longer cover up problems Pervasive and persistent memory loss impacts
life across settings Rambling speech unusual reasoning
confusion about current events time and place
Nearly 80 of patients exhibit emotional and behavioral problems which are aggravated by stress and change
2) Second stage
Last stage
This is considered as the severe stage the duration is 1-3 years Generally incapacitated with severe to
total loss of verbal skills Unable to care for self Extreme problems with mood behavioral
problems hallucinations and delirium
Neurons
bull The brain has billions of neurons each with an axon and many dendrites
bull To stay healthy neurons must communicate with each other carry out metabolism and repair themselves
bull AD disrupts all three of these essential jobs
Inside the Human Brain
Slide 14
Plaques and Tangles The Hallmarks of AD
The brains of people with AD have an abundance of two abnormal structures
An actual AD plaque An actual AD tangle
bull beta-amyloid plaques which are dense deposits of protein and cellular material that accumulate outside and around nerve cells
bull neurofibrillary tangles which are twisted fibers that build up inside the nerve cell
Slide 16
Beta-amyloid Plaques
Amyloid precursor protein (APP) is the precursor to amyloid plaque
1 APP sticks through the neuron membrane
2 Enzymes cut the APP into fragments of protein including beta-amyloid
3 Beta-amyloid fragments come together in clumps to form plaques
1
2
3
In AD many of these clumps form disrupting the work of neurons This affects the hippocampus and other areas of the cerebral cortex
Slide 17
Neurofibrillary Tangles
Neurons have an internal support structure partly made up of microtubules A protein called tau helps stabilize microtubules In AD tau changes causing microtubules to collapse and tau proteins clump together to form neurofibrillary tangles
AD and the Brain
Slide 18
The Changing Brain in Alzheimerrsquos Disease
No one knows what causes AD to begin but we do know a lot about what happens in the brain once AD takes hold
Pet Scan of Normal Brain
Pet Scan of Alzheimerrsquos Disease Brain
Slide 19
Causes for AD
bull AD develops when genetic lifestyle and environmental factors work together to cause the disease process to start
Slide 24
Genetic Studies
The two main types of AD are early-onset and late-onset
bull Early-onset AD is rare usually affecting people aged 30 to 60 and usually running in families Researchers have identified mutations in three genes that cause early-onset AD
bull Late-onset AD is more common It usually affects people over age 65 Researchers have identified
a gene that produces a protein called apolipoprotein E (ApoE) Scientists believe this protein is involved in the formation of beta-amyloid plaques
Slide 25
Environment and lifestyle factors
Diet ndash Diet can affect a persons risk of developing many types of illness including dementia A healthy and balanced diet that enables a person to maintain a normal body weight is likely to reduce the likelihood of developing high blood pressure or heart disease both of which put a person at greater risk of developing dementia
Smoking ndash Smoking has an extremely harmful effect on the heart lungs and vascular system including the blood vessels in the brain This significantly increases the risk of developing dementia
Alcohol ndash Drinking above recommended levels of alcohol significantly increases the risk of developing dementias such as Alzheimers and vascular dementia However research suggests that light-to-moderate amounts of alcohol may protect the brain against dementia and keep the heart and vascular system healthy
Social activity ndash Research suggests that people who are more socially active have a slightly reduced risk of developing dementia
Mental activity ndash Research suggests that people who take part in mental activities (such as reading learning and doing puzzles) are less likely to develop dementia compared with those who do not engage in these activities
Continuedhelliphelliphelliphelliphelliphellip
Diagnosing for AD
Diagnosing AD
Experienced physicians in specialized AD centers can now diagnose AD with up to 90 percent accuracy Early diagnosis has advantages
bull Doctors can rule out other conditions that may cause dementia
bull If it is AD families have more time to plan for the future
bull Treatments can start earlier when they may be more effective
bull It helps scientists learn more about the causes and development of AD
Slide 29
Physicians today use a number of tools to diagnose AD
bull a detailed patient history
bull information from family and friends
bull physical and neurological exams and lab tests
bull neuropsychological tests
bull imaging tools such as CT scan or magnetic resonance imaging (MRI) PET scans are used primarily for research purposes
CONTINUEDhelliphelliphelliphelliphelliphellip
Slide 30
Clinical trials are the primary way that researchers find out if a promising treatment is safe and effective
bull Trials examine approved drugs to see if they can be used for other purposes or look at experimental drugs
bull Participating in a trial means regular contact with the study team who can provide state-of-the-art AD care
Clinical Trials
Slide 31
Drugs used to treat mild to moderate AD symptoms include
bull Aricept
bull Exelon
bull Reminyl
An additional drug Namenda has been approved to treat symptoms of moderate to severe AD These drugs can help improve some patientsrsquo abilities to carry out activities up to a year or so but they do not stop or reverse AD
Scientists are also studying agents that someday may be useful in preventing AD For example they have experimented with a vaccine against AD Although the first clinical trial was stopped due to side effects in some participants valuable information was gathered
Treatments for AD
Slide 32
Researchers also are looking at other treatments including
bull cholesterol-lowering drugs called statins
bull anti-oxidants (vitamins) and folic acid
bull anti-inflammatory drugs
bull substances that prevent formation of beta-amyloid plaques
bull nerve growth factor to keep neurons healthy
Search for New Treatments
Slide 33
Who are the AD Caregiversbull Spouses ndash the largest group Most are older with
their own health problemsbull Daughters ndash the second largest group Called the
ldquosandwich generationrdquo many are married and raising children of their own Children may need extra support if a parentrsquos attention is focused on care giving
bull Grandchildren ndash may become major helpers
bull Daughters-in-law ndash the third largest group bull Sons ndash often focus on the financial legal and
business aspects of care giving bull Brothers and Sisters ndash many are older with
their own health problemsbull Other ndash friends neighbors members of the
faith community
Support for Caregivers
Slide 37
The NIA is studying how computers can provide information and support to family caregivers through
These features have become very popular among users because they reach many people at once are private and convenient and are available around the clock
bull computer-based bulletin boardsbull chat roomsbull Q amp A modulesbull medical advice forums
Slide 39
Technology and Care giving
One of the great mysteries of Alzheimerrsquos disease is why it largely strikes older adults
Research on how the brain changes normally with age is shedding light on this question For example scientists are learning how age-related changes in the brain may harm neurons and contribute to Alzheimerrsquos damage These age-related changes include atrophy (shrinking) of certain parts of the brain inflammation the production of unstable molecules called free radicals and mitochondrial dysfunction (a breakdown of energy production within a cell)
bull Generally it is diagnosed in people over 65 years of age although the less-prevalent early onset of Alzheimerrsquos can occur much earlier
bull In 2006 there were 266 million sufferers worldwide
bull Alzheimerrsquos is predicted to affect 1 in 85 people globally by 2050
Signs Of Normal Change vs Early Alzheimerrsquos Symptoms
Normal Early Alzheimerrsquos Disease
Canrsquot find your keys Routinely place important items in odd places such as keys in the fridge wallet in the dishwasher
Search for casual names and words
Forget names of family members and common objects or substitute words with inappropriate ones
Briefly forget conversation details
Frequently forget entire conversations
Feel the cold more Dress regardless of the weather wear several skirts on a warm day or shorts in a snow storm
Canrsquot find a recipe Canrsquot follow recipe directions
Forget to record a check Can no longer manage checkbook balance figures solve problems or think abstractly
Cancel a date with friends Withdraw from usual interests and activities sit in front of the TV for hours sleep far more than usual
Make an occasional wrong turn
Get lost in familiar places donrsquot remember how you got there or how to get home
Feel occasionally sad Experience rapid mood swings from tears to rage for no discernible reason
Life expectancyOn average people with Alzheimers disease live for around 8 to 10 years after they start to develop symptoms However this can vary considerably from person to person Some people with the condition will live longer than this but others will not
Alzheimers disease is not usually the actual cause of death but it is often a contributing factor For example a leading cause of death in people with Alzheimers disease is pneumonia (lung infection) which may go untreated because people with the condition often arent able to recognize that theyre ill or may not be able to tell someone they are feeling unwell
RESULTS 1203 subjects were resurveyed in 1997 and among them 124 new cases of dementia including 81 cases of AD were identified By computing the relative risk(RR) of psychosocial factors to the AD many psychosocial factors were found to be correlated with AD including blue collar occupation no job no reading or writing no taking community activities no gardening in leisure bad psychological feeling and lower education (RR gt 1) The items with high PARP gt 50 were not working no job retirement no taking community activities no reading or writing blue collar occupation and no gardening in leisure MMSE total score is a good predict for AD
Psychosocial risk factors of Alzheimers disease
Too much cake and chocolate could cause Alzheimers disease new research claims
Risk The study adds further evidence to links between diabetes and dementia
Eating too many chocolates cakes and other sugary treats could help trigger Alzheimerrsquos disease says new research
bullA study in mice found high levels of blood sugar rapidly increased rogue proteins in the body which combine and kill brain cells ultimately leading to dementia
CONTINUEDhelliphelliphelliphelliphellip
Green tea has also been proven to have beneficial effects when it comes to
Alzheimers(ALAMY)
Some famous books on Alzheimers
The 36-Hour Day fifth edition The 36-Hour by Nancy L Mace
Learning to Speak Alzheimers A Groundbrea
by Joanne Koenig Coste
The Validation Breakthrough Third Edition by Naomi Feil MSW
Alzheimers Disease What If There Was a Cu by Mary T Newport
A Caregivers Guide to Alzheimers Disease by Patricia R Callone
Creating Moments of Joy for the Person with by Jolene Brackey
Alzheimers Early Stages First Steps for F by Daniel Kuhn
Alzheimers Disease and Other Dementias - T by Nataly Rubinstein
Alzheimers For Dummies by Patricia B Smith
Some famous person died of Alzheimers
Fantasy author Sir Terry Pratchett dies at 66
Sir Terry Pratchett renowned fantasy author of more than 70 books has died at age 66
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
This is considered as a middlemoderate stage the duration is 2-10 years Can no longer cover up problems Pervasive and persistent memory loss impacts
life across settings Rambling speech unusual reasoning
confusion about current events time and place
Nearly 80 of patients exhibit emotional and behavioral problems which are aggravated by stress and change
2) Second stage
Last stage
This is considered as the severe stage the duration is 1-3 years Generally incapacitated with severe to
total loss of verbal skills Unable to care for self Extreme problems with mood behavioral
problems hallucinations and delirium
Neurons
bull The brain has billions of neurons each with an axon and many dendrites
bull To stay healthy neurons must communicate with each other carry out metabolism and repair themselves
bull AD disrupts all three of these essential jobs
Inside the Human Brain
Slide 14
Plaques and Tangles The Hallmarks of AD
The brains of people with AD have an abundance of two abnormal structures
An actual AD plaque An actual AD tangle
bull beta-amyloid plaques which are dense deposits of protein and cellular material that accumulate outside and around nerve cells
bull neurofibrillary tangles which are twisted fibers that build up inside the nerve cell
Slide 16
Beta-amyloid Plaques
Amyloid precursor protein (APP) is the precursor to amyloid plaque
1 APP sticks through the neuron membrane
2 Enzymes cut the APP into fragments of protein including beta-amyloid
3 Beta-amyloid fragments come together in clumps to form plaques
1
2
3
In AD many of these clumps form disrupting the work of neurons This affects the hippocampus and other areas of the cerebral cortex
Slide 17
Neurofibrillary Tangles
Neurons have an internal support structure partly made up of microtubules A protein called tau helps stabilize microtubules In AD tau changes causing microtubules to collapse and tau proteins clump together to form neurofibrillary tangles
AD and the Brain
Slide 18
The Changing Brain in Alzheimerrsquos Disease
No one knows what causes AD to begin but we do know a lot about what happens in the brain once AD takes hold
Pet Scan of Normal Brain
Pet Scan of Alzheimerrsquos Disease Brain
Slide 19
Causes for AD
bull AD develops when genetic lifestyle and environmental factors work together to cause the disease process to start
Slide 24
Genetic Studies
The two main types of AD are early-onset and late-onset
bull Early-onset AD is rare usually affecting people aged 30 to 60 and usually running in families Researchers have identified mutations in three genes that cause early-onset AD
bull Late-onset AD is more common It usually affects people over age 65 Researchers have identified
a gene that produces a protein called apolipoprotein E (ApoE) Scientists believe this protein is involved in the formation of beta-amyloid plaques
Slide 25
Environment and lifestyle factors
Diet ndash Diet can affect a persons risk of developing many types of illness including dementia A healthy and balanced diet that enables a person to maintain a normal body weight is likely to reduce the likelihood of developing high blood pressure or heart disease both of which put a person at greater risk of developing dementia
Smoking ndash Smoking has an extremely harmful effect on the heart lungs and vascular system including the blood vessels in the brain This significantly increases the risk of developing dementia
Alcohol ndash Drinking above recommended levels of alcohol significantly increases the risk of developing dementias such as Alzheimers and vascular dementia However research suggests that light-to-moderate amounts of alcohol may protect the brain against dementia and keep the heart and vascular system healthy
Social activity ndash Research suggests that people who are more socially active have a slightly reduced risk of developing dementia
Mental activity ndash Research suggests that people who take part in mental activities (such as reading learning and doing puzzles) are less likely to develop dementia compared with those who do not engage in these activities
Continuedhelliphelliphelliphelliphelliphellip
Diagnosing for AD
Diagnosing AD
Experienced physicians in specialized AD centers can now diagnose AD with up to 90 percent accuracy Early diagnosis has advantages
bull Doctors can rule out other conditions that may cause dementia
bull If it is AD families have more time to plan for the future
bull Treatments can start earlier when they may be more effective
bull It helps scientists learn more about the causes and development of AD
Slide 29
Physicians today use a number of tools to diagnose AD
bull a detailed patient history
bull information from family and friends
bull physical and neurological exams and lab tests
bull neuropsychological tests
bull imaging tools such as CT scan or magnetic resonance imaging (MRI) PET scans are used primarily for research purposes
CONTINUEDhelliphelliphelliphelliphelliphellip
Slide 30
Clinical trials are the primary way that researchers find out if a promising treatment is safe and effective
bull Trials examine approved drugs to see if they can be used for other purposes or look at experimental drugs
bull Participating in a trial means regular contact with the study team who can provide state-of-the-art AD care
Clinical Trials
Slide 31
Drugs used to treat mild to moderate AD symptoms include
bull Aricept
bull Exelon
bull Reminyl
An additional drug Namenda has been approved to treat symptoms of moderate to severe AD These drugs can help improve some patientsrsquo abilities to carry out activities up to a year or so but they do not stop or reverse AD
Scientists are also studying agents that someday may be useful in preventing AD For example they have experimented with a vaccine against AD Although the first clinical trial was stopped due to side effects in some participants valuable information was gathered
Treatments for AD
Slide 32
Researchers also are looking at other treatments including
bull cholesterol-lowering drugs called statins
bull anti-oxidants (vitamins) and folic acid
bull anti-inflammatory drugs
bull substances that prevent formation of beta-amyloid plaques
bull nerve growth factor to keep neurons healthy
Search for New Treatments
Slide 33
Who are the AD Caregiversbull Spouses ndash the largest group Most are older with
their own health problemsbull Daughters ndash the second largest group Called the
ldquosandwich generationrdquo many are married and raising children of their own Children may need extra support if a parentrsquos attention is focused on care giving
bull Grandchildren ndash may become major helpers
bull Daughters-in-law ndash the third largest group bull Sons ndash often focus on the financial legal and
business aspects of care giving bull Brothers and Sisters ndash many are older with
their own health problemsbull Other ndash friends neighbors members of the
faith community
Support for Caregivers
Slide 37
The NIA is studying how computers can provide information and support to family caregivers through
These features have become very popular among users because they reach many people at once are private and convenient and are available around the clock
bull computer-based bulletin boardsbull chat roomsbull Q amp A modulesbull medical advice forums
Slide 39
Technology and Care giving
One of the great mysteries of Alzheimerrsquos disease is why it largely strikes older adults
Research on how the brain changes normally with age is shedding light on this question For example scientists are learning how age-related changes in the brain may harm neurons and contribute to Alzheimerrsquos damage These age-related changes include atrophy (shrinking) of certain parts of the brain inflammation the production of unstable molecules called free radicals and mitochondrial dysfunction (a breakdown of energy production within a cell)
bull Generally it is diagnosed in people over 65 years of age although the less-prevalent early onset of Alzheimerrsquos can occur much earlier
bull In 2006 there were 266 million sufferers worldwide
bull Alzheimerrsquos is predicted to affect 1 in 85 people globally by 2050
Signs Of Normal Change vs Early Alzheimerrsquos Symptoms
Normal Early Alzheimerrsquos Disease
Canrsquot find your keys Routinely place important items in odd places such as keys in the fridge wallet in the dishwasher
Search for casual names and words
Forget names of family members and common objects or substitute words with inappropriate ones
Briefly forget conversation details
Frequently forget entire conversations
Feel the cold more Dress regardless of the weather wear several skirts on a warm day or shorts in a snow storm
Canrsquot find a recipe Canrsquot follow recipe directions
Forget to record a check Can no longer manage checkbook balance figures solve problems or think abstractly
Cancel a date with friends Withdraw from usual interests and activities sit in front of the TV for hours sleep far more than usual
Make an occasional wrong turn
Get lost in familiar places donrsquot remember how you got there or how to get home
Feel occasionally sad Experience rapid mood swings from tears to rage for no discernible reason
Life expectancyOn average people with Alzheimers disease live for around 8 to 10 years after they start to develop symptoms However this can vary considerably from person to person Some people with the condition will live longer than this but others will not
Alzheimers disease is not usually the actual cause of death but it is often a contributing factor For example a leading cause of death in people with Alzheimers disease is pneumonia (lung infection) which may go untreated because people with the condition often arent able to recognize that theyre ill or may not be able to tell someone they are feeling unwell
RESULTS 1203 subjects were resurveyed in 1997 and among them 124 new cases of dementia including 81 cases of AD were identified By computing the relative risk(RR) of psychosocial factors to the AD many psychosocial factors were found to be correlated with AD including blue collar occupation no job no reading or writing no taking community activities no gardening in leisure bad psychological feeling and lower education (RR gt 1) The items with high PARP gt 50 were not working no job retirement no taking community activities no reading or writing blue collar occupation and no gardening in leisure MMSE total score is a good predict for AD
Psychosocial risk factors of Alzheimers disease
Too much cake and chocolate could cause Alzheimers disease new research claims
Risk The study adds further evidence to links between diabetes and dementia
Eating too many chocolates cakes and other sugary treats could help trigger Alzheimerrsquos disease says new research
bullA study in mice found high levels of blood sugar rapidly increased rogue proteins in the body which combine and kill brain cells ultimately leading to dementia
CONTINUEDhelliphelliphelliphelliphellip
Green tea has also been proven to have beneficial effects when it comes to
Alzheimers(ALAMY)
Some famous books on Alzheimers
The 36-Hour Day fifth edition The 36-Hour by Nancy L Mace
Learning to Speak Alzheimers A Groundbrea
by Joanne Koenig Coste
The Validation Breakthrough Third Edition by Naomi Feil MSW
Alzheimers Disease What If There Was a Cu by Mary T Newport
A Caregivers Guide to Alzheimers Disease by Patricia R Callone
Creating Moments of Joy for the Person with by Jolene Brackey
Alzheimers Early Stages First Steps for F by Daniel Kuhn
Alzheimers Disease and Other Dementias - T by Nataly Rubinstein
Alzheimers For Dummies by Patricia B Smith
Some famous person died of Alzheimers
Fantasy author Sir Terry Pratchett dies at 66
Sir Terry Pratchett renowned fantasy author of more than 70 books has died at age 66
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Last stage
This is considered as the severe stage the duration is 1-3 years Generally incapacitated with severe to
total loss of verbal skills Unable to care for self Extreme problems with mood behavioral
problems hallucinations and delirium
Neurons
bull The brain has billions of neurons each with an axon and many dendrites
bull To stay healthy neurons must communicate with each other carry out metabolism and repair themselves
bull AD disrupts all three of these essential jobs
Inside the Human Brain
Slide 14
Plaques and Tangles The Hallmarks of AD
The brains of people with AD have an abundance of two abnormal structures
An actual AD plaque An actual AD tangle
bull beta-amyloid plaques which are dense deposits of protein and cellular material that accumulate outside and around nerve cells
bull neurofibrillary tangles which are twisted fibers that build up inside the nerve cell
Slide 16
Beta-amyloid Plaques
Amyloid precursor protein (APP) is the precursor to amyloid plaque
1 APP sticks through the neuron membrane
2 Enzymes cut the APP into fragments of protein including beta-amyloid
3 Beta-amyloid fragments come together in clumps to form plaques
1
2
3
In AD many of these clumps form disrupting the work of neurons This affects the hippocampus and other areas of the cerebral cortex
Slide 17
Neurofibrillary Tangles
Neurons have an internal support structure partly made up of microtubules A protein called tau helps stabilize microtubules In AD tau changes causing microtubules to collapse and tau proteins clump together to form neurofibrillary tangles
AD and the Brain
Slide 18
The Changing Brain in Alzheimerrsquos Disease
No one knows what causes AD to begin but we do know a lot about what happens in the brain once AD takes hold
Pet Scan of Normal Brain
Pet Scan of Alzheimerrsquos Disease Brain
Slide 19
Causes for AD
bull AD develops when genetic lifestyle and environmental factors work together to cause the disease process to start
Slide 24
Genetic Studies
The two main types of AD are early-onset and late-onset
bull Early-onset AD is rare usually affecting people aged 30 to 60 and usually running in families Researchers have identified mutations in three genes that cause early-onset AD
bull Late-onset AD is more common It usually affects people over age 65 Researchers have identified
a gene that produces a protein called apolipoprotein E (ApoE) Scientists believe this protein is involved in the formation of beta-amyloid plaques
Slide 25
Environment and lifestyle factors
Diet ndash Diet can affect a persons risk of developing many types of illness including dementia A healthy and balanced diet that enables a person to maintain a normal body weight is likely to reduce the likelihood of developing high blood pressure or heart disease both of which put a person at greater risk of developing dementia
Smoking ndash Smoking has an extremely harmful effect on the heart lungs and vascular system including the blood vessels in the brain This significantly increases the risk of developing dementia
Alcohol ndash Drinking above recommended levels of alcohol significantly increases the risk of developing dementias such as Alzheimers and vascular dementia However research suggests that light-to-moderate amounts of alcohol may protect the brain against dementia and keep the heart and vascular system healthy
Social activity ndash Research suggests that people who are more socially active have a slightly reduced risk of developing dementia
Mental activity ndash Research suggests that people who take part in mental activities (such as reading learning and doing puzzles) are less likely to develop dementia compared with those who do not engage in these activities
Continuedhelliphelliphelliphelliphelliphellip
Diagnosing for AD
Diagnosing AD
Experienced physicians in specialized AD centers can now diagnose AD with up to 90 percent accuracy Early diagnosis has advantages
bull Doctors can rule out other conditions that may cause dementia
bull If it is AD families have more time to plan for the future
bull Treatments can start earlier when they may be more effective
bull It helps scientists learn more about the causes and development of AD
Slide 29
Physicians today use a number of tools to diagnose AD
bull a detailed patient history
bull information from family and friends
bull physical and neurological exams and lab tests
bull neuropsychological tests
bull imaging tools such as CT scan or magnetic resonance imaging (MRI) PET scans are used primarily for research purposes
CONTINUEDhelliphelliphelliphelliphelliphellip
Slide 30
Clinical trials are the primary way that researchers find out if a promising treatment is safe and effective
bull Trials examine approved drugs to see if they can be used for other purposes or look at experimental drugs
bull Participating in a trial means regular contact with the study team who can provide state-of-the-art AD care
Clinical Trials
Slide 31
Drugs used to treat mild to moderate AD symptoms include
bull Aricept
bull Exelon
bull Reminyl
An additional drug Namenda has been approved to treat symptoms of moderate to severe AD These drugs can help improve some patientsrsquo abilities to carry out activities up to a year or so but they do not stop or reverse AD
Scientists are also studying agents that someday may be useful in preventing AD For example they have experimented with a vaccine against AD Although the first clinical trial was stopped due to side effects in some participants valuable information was gathered
Treatments for AD
Slide 32
Researchers also are looking at other treatments including
bull cholesterol-lowering drugs called statins
bull anti-oxidants (vitamins) and folic acid
bull anti-inflammatory drugs
bull substances that prevent formation of beta-amyloid plaques
bull nerve growth factor to keep neurons healthy
Search for New Treatments
Slide 33
Who are the AD Caregiversbull Spouses ndash the largest group Most are older with
their own health problemsbull Daughters ndash the second largest group Called the
ldquosandwich generationrdquo many are married and raising children of their own Children may need extra support if a parentrsquos attention is focused on care giving
bull Grandchildren ndash may become major helpers
bull Daughters-in-law ndash the third largest group bull Sons ndash often focus on the financial legal and
business aspects of care giving bull Brothers and Sisters ndash many are older with
their own health problemsbull Other ndash friends neighbors members of the
faith community
Support for Caregivers
Slide 37
The NIA is studying how computers can provide information and support to family caregivers through
These features have become very popular among users because they reach many people at once are private and convenient and are available around the clock
bull computer-based bulletin boardsbull chat roomsbull Q amp A modulesbull medical advice forums
Slide 39
Technology and Care giving
One of the great mysteries of Alzheimerrsquos disease is why it largely strikes older adults
Research on how the brain changes normally with age is shedding light on this question For example scientists are learning how age-related changes in the brain may harm neurons and contribute to Alzheimerrsquos damage These age-related changes include atrophy (shrinking) of certain parts of the brain inflammation the production of unstable molecules called free radicals and mitochondrial dysfunction (a breakdown of energy production within a cell)
bull Generally it is diagnosed in people over 65 years of age although the less-prevalent early onset of Alzheimerrsquos can occur much earlier
bull In 2006 there were 266 million sufferers worldwide
bull Alzheimerrsquos is predicted to affect 1 in 85 people globally by 2050
Signs Of Normal Change vs Early Alzheimerrsquos Symptoms
Normal Early Alzheimerrsquos Disease
Canrsquot find your keys Routinely place important items in odd places such as keys in the fridge wallet in the dishwasher
Search for casual names and words
Forget names of family members and common objects or substitute words with inappropriate ones
Briefly forget conversation details
Frequently forget entire conversations
Feel the cold more Dress regardless of the weather wear several skirts on a warm day or shorts in a snow storm
Canrsquot find a recipe Canrsquot follow recipe directions
Forget to record a check Can no longer manage checkbook balance figures solve problems or think abstractly
Cancel a date with friends Withdraw from usual interests and activities sit in front of the TV for hours sleep far more than usual
Make an occasional wrong turn
Get lost in familiar places donrsquot remember how you got there or how to get home
Feel occasionally sad Experience rapid mood swings from tears to rage for no discernible reason
Life expectancyOn average people with Alzheimers disease live for around 8 to 10 years after they start to develop symptoms However this can vary considerably from person to person Some people with the condition will live longer than this but others will not
Alzheimers disease is not usually the actual cause of death but it is often a contributing factor For example a leading cause of death in people with Alzheimers disease is pneumonia (lung infection) which may go untreated because people with the condition often arent able to recognize that theyre ill or may not be able to tell someone they are feeling unwell
RESULTS 1203 subjects were resurveyed in 1997 and among them 124 new cases of dementia including 81 cases of AD were identified By computing the relative risk(RR) of psychosocial factors to the AD many psychosocial factors were found to be correlated with AD including blue collar occupation no job no reading or writing no taking community activities no gardening in leisure bad psychological feeling and lower education (RR gt 1) The items with high PARP gt 50 were not working no job retirement no taking community activities no reading or writing blue collar occupation and no gardening in leisure MMSE total score is a good predict for AD
Psychosocial risk factors of Alzheimers disease
Too much cake and chocolate could cause Alzheimers disease new research claims
Risk The study adds further evidence to links between diabetes and dementia
Eating too many chocolates cakes and other sugary treats could help trigger Alzheimerrsquos disease says new research
bullA study in mice found high levels of blood sugar rapidly increased rogue proteins in the body which combine and kill brain cells ultimately leading to dementia
CONTINUEDhelliphelliphelliphelliphellip
Green tea has also been proven to have beneficial effects when it comes to
Alzheimers(ALAMY)
Some famous books on Alzheimers
The 36-Hour Day fifth edition The 36-Hour by Nancy L Mace
Learning to Speak Alzheimers A Groundbrea
by Joanne Koenig Coste
The Validation Breakthrough Third Edition by Naomi Feil MSW
Alzheimers Disease What If There Was a Cu by Mary T Newport
A Caregivers Guide to Alzheimers Disease by Patricia R Callone
Creating Moments of Joy for the Person with by Jolene Brackey
Alzheimers Early Stages First Steps for F by Daniel Kuhn
Alzheimers Disease and Other Dementias - T by Nataly Rubinstein
Alzheimers For Dummies by Patricia B Smith
Some famous person died of Alzheimers
Fantasy author Sir Terry Pratchett dies at 66
Sir Terry Pratchett renowned fantasy author of more than 70 books has died at age 66
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Neurons
bull The brain has billions of neurons each with an axon and many dendrites
bull To stay healthy neurons must communicate with each other carry out metabolism and repair themselves
bull AD disrupts all three of these essential jobs
Inside the Human Brain
Slide 14
Plaques and Tangles The Hallmarks of AD
The brains of people with AD have an abundance of two abnormal structures
An actual AD plaque An actual AD tangle
bull beta-amyloid plaques which are dense deposits of protein and cellular material that accumulate outside and around nerve cells
bull neurofibrillary tangles which are twisted fibers that build up inside the nerve cell
Slide 16
Beta-amyloid Plaques
Amyloid precursor protein (APP) is the precursor to amyloid plaque
1 APP sticks through the neuron membrane
2 Enzymes cut the APP into fragments of protein including beta-amyloid
3 Beta-amyloid fragments come together in clumps to form plaques
1
2
3
In AD many of these clumps form disrupting the work of neurons This affects the hippocampus and other areas of the cerebral cortex
Slide 17
Neurofibrillary Tangles
Neurons have an internal support structure partly made up of microtubules A protein called tau helps stabilize microtubules In AD tau changes causing microtubules to collapse and tau proteins clump together to form neurofibrillary tangles
AD and the Brain
Slide 18
The Changing Brain in Alzheimerrsquos Disease
No one knows what causes AD to begin but we do know a lot about what happens in the brain once AD takes hold
Pet Scan of Normal Brain
Pet Scan of Alzheimerrsquos Disease Brain
Slide 19
Causes for AD
bull AD develops when genetic lifestyle and environmental factors work together to cause the disease process to start
Slide 24
Genetic Studies
The two main types of AD are early-onset and late-onset
bull Early-onset AD is rare usually affecting people aged 30 to 60 and usually running in families Researchers have identified mutations in three genes that cause early-onset AD
bull Late-onset AD is more common It usually affects people over age 65 Researchers have identified
a gene that produces a protein called apolipoprotein E (ApoE) Scientists believe this protein is involved in the formation of beta-amyloid plaques
Slide 25
Environment and lifestyle factors
Diet ndash Diet can affect a persons risk of developing many types of illness including dementia A healthy and balanced diet that enables a person to maintain a normal body weight is likely to reduce the likelihood of developing high blood pressure or heart disease both of which put a person at greater risk of developing dementia
Smoking ndash Smoking has an extremely harmful effect on the heart lungs and vascular system including the blood vessels in the brain This significantly increases the risk of developing dementia
Alcohol ndash Drinking above recommended levels of alcohol significantly increases the risk of developing dementias such as Alzheimers and vascular dementia However research suggests that light-to-moderate amounts of alcohol may protect the brain against dementia and keep the heart and vascular system healthy
Social activity ndash Research suggests that people who are more socially active have a slightly reduced risk of developing dementia
Mental activity ndash Research suggests that people who take part in mental activities (such as reading learning and doing puzzles) are less likely to develop dementia compared with those who do not engage in these activities
Continuedhelliphelliphelliphelliphelliphellip
Diagnosing for AD
Diagnosing AD
Experienced physicians in specialized AD centers can now diagnose AD with up to 90 percent accuracy Early diagnosis has advantages
bull Doctors can rule out other conditions that may cause dementia
bull If it is AD families have more time to plan for the future
bull Treatments can start earlier when they may be more effective
bull It helps scientists learn more about the causes and development of AD
Slide 29
Physicians today use a number of tools to diagnose AD
bull a detailed patient history
bull information from family and friends
bull physical and neurological exams and lab tests
bull neuropsychological tests
bull imaging tools such as CT scan or magnetic resonance imaging (MRI) PET scans are used primarily for research purposes
CONTINUEDhelliphelliphelliphelliphelliphellip
Slide 30
Clinical trials are the primary way that researchers find out if a promising treatment is safe and effective
bull Trials examine approved drugs to see if they can be used for other purposes or look at experimental drugs
bull Participating in a trial means regular contact with the study team who can provide state-of-the-art AD care
Clinical Trials
Slide 31
Drugs used to treat mild to moderate AD symptoms include
bull Aricept
bull Exelon
bull Reminyl
An additional drug Namenda has been approved to treat symptoms of moderate to severe AD These drugs can help improve some patientsrsquo abilities to carry out activities up to a year or so but they do not stop or reverse AD
Scientists are also studying agents that someday may be useful in preventing AD For example they have experimented with a vaccine against AD Although the first clinical trial was stopped due to side effects in some participants valuable information was gathered
Treatments for AD
Slide 32
Researchers also are looking at other treatments including
bull cholesterol-lowering drugs called statins
bull anti-oxidants (vitamins) and folic acid
bull anti-inflammatory drugs
bull substances that prevent formation of beta-amyloid plaques
bull nerve growth factor to keep neurons healthy
Search for New Treatments
Slide 33
Who are the AD Caregiversbull Spouses ndash the largest group Most are older with
their own health problemsbull Daughters ndash the second largest group Called the
ldquosandwich generationrdquo many are married and raising children of their own Children may need extra support if a parentrsquos attention is focused on care giving
bull Grandchildren ndash may become major helpers
bull Daughters-in-law ndash the third largest group bull Sons ndash often focus on the financial legal and
business aspects of care giving bull Brothers and Sisters ndash many are older with
their own health problemsbull Other ndash friends neighbors members of the
faith community
Support for Caregivers
Slide 37
The NIA is studying how computers can provide information and support to family caregivers through
These features have become very popular among users because they reach many people at once are private and convenient and are available around the clock
bull computer-based bulletin boardsbull chat roomsbull Q amp A modulesbull medical advice forums
Slide 39
Technology and Care giving
One of the great mysteries of Alzheimerrsquos disease is why it largely strikes older adults
Research on how the brain changes normally with age is shedding light on this question For example scientists are learning how age-related changes in the brain may harm neurons and contribute to Alzheimerrsquos damage These age-related changes include atrophy (shrinking) of certain parts of the brain inflammation the production of unstable molecules called free radicals and mitochondrial dysfunction (a breakdown of energy production within a cell)
bull Generally it is diagnosed in people over 65 years of age although the less-prevalent early onset of Alzheimerrsquos can occur much earlier
bull In 2006 there were 266 million sufferers worldwide
bull Alzheimerrsquos is predicted to affect 1 in 85 people globally by 2050
Signs Of Normal Change vs Early Alzheimerrsquos Symptoms
Normal Early Alzheimerrsquos Disease
Canrsquot find your keys Routinely place important items in odd places such as keys in the fridge wallet in the dishwasher
Search for casual names and words
Forget names of family members and common objects or substitute words with inappropriate ones
Briefly forget conversation details
Frequently forget entire conversations
Feel the cold more Dress regardless of the weather wear several skirts on a warm day or shorts in a snow storm
Canrsquot find a recipe Canrsquot follow recipe directions
Forget to record a check Can no longer manage checkbook balance figures solve problems or think abstractly
Cancel a date with friends Withdraw from usual interests and activities sit in front of the TV for hours sleep far more than usual
Make an occasional wrong turn
Get lost in familiar places donrsquot remember how you got there or how to get home
Feel occasionally sad Experience rapid mood swings from tears to rage for no discernible reason
Life expectancyOn average people with Alzheimers disease live for around 8 to 10 years after they start to develop symptoms However this can vary considerably from person to person Some people with the condition will live longer than this but others will not
Alzheimers disease is not usually the actual cause of death but it is often a contributing factor For example a leading cause of death in people with Alzheimers disease is pneumonia (lung infection) which may go untreated because people with the condition often arent able to recognize that theyre ill or may not be able to tell someone they are feeling unwell
RESULTS 1203 subjects were resurveyed in 1997 and among them 124 new cases of dementia including 81 cases of AD were identified By computing the relative risk(RR) of psychosocial factors to the AD many psychosocial factors were found to be correlated with AD including blue collar occupation no job no reading or writing no taking community activities no gardening in leisure bad psychological feeling and lower education (RR gt 1) The items with high PARP gt 50 were not working no job retirement no taking community activities no reading or writing blue collar occupation and no gardening in leisure MMSE total score is a good predict for AD
Psychosocial risk factors of Alzheimers disease
Too much cake and chocolate could cause Alzheimers disease new research claims
Risk The study adds further evidence to links between diabetes and dementia
Eating too many chocolates cakes and other sugary treats could help trigger Alzheimerrsquos disease says new research
bullA study in mice found high levels of blood sugar rapidly increased rogue proteins in the body which combine and kill brain cells ultimately leading to dementia
CONTINUEDhelliphelliphelliphelliphellip
Green tea has also been proven to have beneficial effects when it comes to
Alzheimers(ALAMY)
Some famous books on Alzheimers
The 36-Hour Day fifth edition The 36-Hour by Nancy L Mace
Learning to Speak Alzheimers A Groundbrea
by Joanne Koenig Coste
The Validation Breakthrough Third Edition by Naomi Feil MSW
Alzheimers Disease What If There Was a Cu by Mary T Newport
A Caregivers Guide to Alzheimers Disease by Patricia R Callone
Creating Moments of Joy for the Person with by Jolene Brackey
Alzheimers Early Stages First Steps for F by Daniel Kuhn
Alzheimers Disease and Other Dementias - T by Nataly Rubinstein
Alzheimers For Dummies by Patricia B Smith
Some famous person died of Alzheimers
Fantasy author Sir Terry Pratchett dies at 66
Sir Terry Pratchett renowned fantasy author of more than 70 books has died at age 66
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Plaques and Tangles The Hallmarks of AD
The brains of people with AD have an abundance of two abnormal structures
An actual AD plaque An actual AD tangle
bull beta-amyloid plaques which are dense deposits of protein and cellular material that accumulate outside and around nerve cells
bull neurofibrillary tangles which are twisted fibers that build up inside the nerve cell
Slide 16
Beta-amyloid Plaques
Amyloid precursor protein (APP) is the precursor to amyloid plaque
1 APP sticks through the neuron membrane
2 Enzymes cut the APP into fragments of protein including beta-amyloid
3 Beta-amyloid fragments come together in clumps to form plaques
1
2
3
In AD many of these clumps form disrupting the work of neurons This affects the hippocampus and other areas of the cerebral cortex
Slide 17
Neurofibrillary Tangles
Neurons have an internal support structure partly made up of microtubules A protein called tau helps stabilize microtubules In AD tau changes causing microtubules to collapse and tau proteins clump together to form neurofibrillary tangles
AD and the Brain
Slide 18
The Changing Brain in Alzheimerrsquos Disease
No one knows what causes AD to begin but we do know a lot about what happens in the brain once AD takes hold
Pet Scan of Normal Brain
Pet Scan of Alzheimerrsquos Disease Brain
Slide 19
Causes for AD
bull AD develops when genetic lifestyle and environmental factors work together to cause the disease process to start
Slide 24
Genetic Studies
The two main types of AD are early-onset and late-onset
bull Early-onset AD is rare usually affecting people aged 30 to 60 and usually running in families Researchers have identified mutations in three genes that cause early-onset AD
bull Late-onset AD is more common It usually affects people over age 65 Researchers have identified
a gene that produces a protein called apolipoprotein E (ApoE) Scientists believe this protein is involved in the formation of beta-amyloid plaques
Slide 25
Environment and lifestyle factors
Diet ndash Diet can affect a persons risk of developing many types of illness including dementia A healthy and balanced diet that enables a person to maintain a normal body weight is likely to reduce the likelihood of developing high blood pressure or heart disease both of which put a person at greater risk of developing dementia
Smoking ndash Smoking has an extremely harmful effect on the heart lungs and vascular system including the blood vessels in the brain This significantly increases the risk of developing dementia
Alcohol ndash Drinking above recommended levels of alcohol significantly increases the risk of developing dementias such as Alzheimers and vascular dementia However research suggests that light-to-moderate amounts of alcohol may protect the brain against dementia and keep the heart and vascular system healthy
Social activity ndash Research suggests that people who are more socially active have a slightly reduced risk of developing dementia
Mental activity ndash Research suggests that people who take part in mental activities (such as reading learning and doing puzzles) are less likely to develop dementia compared with those who do not engage in these activities
Continuedhelliphelliphelliphelliphelliphellip
Diagnosing for AD
Diagnosing AD
Experienced physicians in specialized AD centers can now diagnose AD with up to 90 percent accuracy Early diagnosis has advantages
bull Doctors can rule out other conditions that may cause dementia
bull If it is AD families have more time to plan for the future
bull Treatments can start earlier when they may be more effective
bull It helps scientists learn more about the causes and development of AD
Slide 29
Physicians today use a number of tools to diagnose AD
bull a detailed patient history
bull information from family and friends
bull physical and neurological exams and lab tests
bull neuropsychological tests
bull imaging tools such as CT scan or magnetic resonance imaging (MRI) PET scans are used primarily for research purposes
CONTINUEDhelliphelliphelliphelliphelliphellip
Slide 30
Clinical trials are the primary way that researchers find out if a promising treatment is safe and effective
bull Trials examine approved drugs to see if they can be used for other purposes or look at experimental drugs
bull Participating in a trial means regular contact with the study team who can provide state-of-the-art AD care
Clinical Trials
Slide 31
Drugs used to treat mild to moderate AD symptoms include
bull Aricept
bull Exelon
bull Reminyl
An additional drug Namenda has been approved to treat symptoms of moderate to severe AD These drugs can help improve some patientsrsquo abilities to carry out activities up to a year or so but they do not stop or reverse AD
Scientists are also studying agents that someday may be useful in preventing AD For example they have experimented with a vaccine against AD Although the first clinical trial was stopped due to side effects in some participants valuable information was gathered
Treatments for AD
Slide 32
Researchers also are looking at other treatments including
bull cholesterol-lowering drugs called statins
bull anti-oxidants (vitamins) and folic acid
bull anti-inflammatory drugs
bull substances that prevent formation of beta-amyloid plaques
bull nerve growth factor to keep neurons healthy
Search for New Treatments
Slide 33
Who are the AD Caregiversbull Spouses ndash the largest group Most are older with
their own health problemsbull Daughters ndash the second largest group Called the
ldquosandwich generationrdquo many are married and raising children of their own Children may need extra support if a parentrsquos attention is focused on care giving
bull Grandchildren ndash may become major helpers
bull Daughters-in-law ndash the third largest group bull Sons ndash often focus on the financial legal and
business aspects of care giving bull Brothers and Sisters ndash many are older with
their own health problemsbull Other ndash friends neighbors members of the
faith community
Support for Caregivers
Slide 37
The NIA is studying how computers can provide information and support to family caregivers through
These features have become very popular among users because they reach many people at once are private and convenient and are available around the clock
bull computer-based bulletin boardsbull chat roomsbull Q amp A modulesbull medical advice forums
Slide 39
Technology and Care giving
One of the great mysteries of Alzheimerrsquos disease is why it largely strikes older adults
Research on how the brain changes normally with age is shedding light on this question For example scientists are learning how age-related changes in the brain may harm neurons and contribute to Alzheimerrsquos damage These age-related changes include atrophy (shrinking) of certain parts of the brain inflammation the production of unstable molecules called free radicals and mitochondrial dysfunction (a breakdown of energy production within a cell)
bull Generally it is diagnosed in people over 65 years of age although the less-prevalent early onset of Alzheimerrsquos can occur much earlier
bull In 2006 there were 266 million sufferers worldwide
bull Alzheimerrsquos is predicted to affect 1 in 85 people globally by 2050
Signs Of Normal Change vs Early Alzheimerrsquos Symptoms
Normal Early Alzheimerrsquos Disease
Canrsquot find your keys Routinely place important items in odd places such as keys in the fridge wallet in the dishwasher
Search for casual names and words
Forget names of family members and common objects or substitute words with inappropriate ones
Briefly forget conversation details
Frequently forget entire conversations
Feel the cold more Dress regardless of the weather wear several skirts on a warm day or shorts in a snow storm
Canrsquot find a recipe Canrsquot follow recipe directions
Forget to record a check Can no longer manage checkbook balance figures solve problems or think abstractly
Cancel a date with friends Withdraw from usual interests and activities sit in front of the TV for hours sleep far more than usual
Make an occasional wrong turn
Get lost in familiar places donrsquot remember how you got there or how to get home
Feel occasionally sad Experience rapid mood swings from tears to rage for no discernible reason
Life expectancyOn average people with Alzheimers disease live for around 8 to 10 years after they start to develop symptoms However this can vary considerably from person to person Some people with the condition will live longer than this but others will not
Alzheimers disease is not usually the actual cause of death but it is often a contributing factor For example a leading cause of death in people with Alzheimers disease is pneumonia (lung infection) which may go untreated because people with the condition often arent able to recognize that theyre ill or may not be able to tell someone they are feeling unwell
RESULTS 1203 subjects were resurveyed in 1997 and among them 124 new cases of dementia including 81 cases of AD were identified By computing the relative risk(RR) of psychosocial factors to the AD many psychosocial factors were found to be correlated with AD including blue collar occupation no job no reading or writing no taking community activities no gardening in leisure bad psychological feeling and lower education (RR gt 1) The items with high PARP gt 50 were not working no job retirement no taking community activities no reading or writing blue collar occupation and no gardening in leisure MMSE total score is a good predict for AD
Psychosocial risk factors of Alzheimers disease
Too much cake and chocolate could cause Alzheimers disease new research claims
Risk The study adds further evidence to links between diabetes and dementia
Eating too many chocolates cakes and other sugary treats could help trigger Alzheimerrsquos disease says new research
bullA study in mice found high levels of blood sugar rapidly increased rogue proteins in the body which combine and kill brain cells ultimately leading to dementia
CONTINUEDhelliphelliphelliphelliphellip
Green tea has also been proven to have beneficial effects when it comes to
Alzheimers(ALAMY)
Some famous books on Alzheimers
The 36-Hour Day fifth edition The 36-Hour by Nancy L Mace
Learning to Speak Alzheimers A Groundbrea
by Joanne Koenig Coste
The Validation Breakthrough Third Edition by Naomi Feil MSW
Alzheimers Disease What If There Was a Cu by Mary T Newport
A Caregivers Guide to Alzheimers Disease by Patricia R Callone
Creating Moments of Joy for the Person with by Jolene Brackey
Alzheimers Early Stages First Steps for F by Daniel Kuhn
Alzheimers Disease and Other Dementias - T by Nataly Rubinstein
Alzheimers For Dummies by Patricia B Smith
Some famous person died of Alzheimers
Fantasy author Sir Terry Pratchett dies at 66
Sir Terry Pratchett renowned fantasy author of more than 70 books has died at age 66
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Beta-amyloid Plaques
Amyloid precursor protein (APP) is the precursor to amyloid plaque
1 APP sticks through the neuron membrane
2 Enzymes cut the APP into fragments of protein including beta-amyloid
3 Beta-amyloid fragments come together in clumps to form plaques
1
2
3
In AD many of these clumps form disrupting the work of neurons This affects the hippocampus and other areas of the cerebral cortex
Slide 17
Neurofibrillary Tangles
Neurons have an internal support structure partly made up of microtubules A protein called tau helps stabilize microtubules In AD tau changes causing microtubules to collapse and tau proteins clump together to form neurofibrillary tangles
AD and the Brain
Slide 18
The Changing Brain in Alzheimerrsquos Disease
No one knows what causes AD to begin but we do know a lot about what happens in the brain once AD takes hold
Pet Scan of Normal Brain
Pet Scan of Alzheimerrsquos Disease Brain
Slide 19
Causes for AD
bull AD develops when genetic lifestyle and environmental factors work together to cause the disease process to start
Slide 24
Genetic Studies
The two main types of AD are early-onset and late-onset
bull Early-onset AD is rare usually affecting people aged 30 to 60 and usually running in families Researchers have identified mutations in three genes that cause early-onset AD
bull Late-onset AD is more common It usually affects people over age 65 Researchers have identified
a gene that produces a protein called apolipoprotein E (ApoE) Scientists believe this protein is involved in the formation of beta-amyloid plaques
Slide 25
Environment and lifestyle factors
Diet ndash Diet can affect a persons risk of developing many types of illness including dementia A healthy and balanced diet that enables a person to maintain a normal body weight is likely to reduce the likelihood of developing high blood pressure or heart disease both of which put a person at greater risk of developing dementia
Smoking ndash Smoking has an extremely harmful effect on the heart lungs and vascular system including the blood vessels in the brain This significantly increases the risk of developing dementia
Alcohol ndash Drinking above recommended levels of alcohol significantly increases the risk of developing dementias such as Alzheimers and vascular dementia However research suggests that light-to-moderate amounts of alcohol may protect the brain against dementia and keep the heart and vascular system healthy
Social activity ndash Research suggests that people who are more socially active have a slightly reduced risk of developing dementia
Mental activity ndash Research suggests that people who take part in mental activities (such as reading learning and doing puzzles) are less likely to develop dementia compared with those who do not engage in these activities
Continuedhelliphelliphelliphelliphelliphellip
Diagnosing for AD
Diagnosing AD
Experienced physicians in specialized AD centers can now diagnose AD with up to 90 percent accuracy Early diagnosis has advantages
bull Doctors can rule out other conditions that may cause dementia
bull If it is AD families have more time to plan for the future
bull Treatments can start earlier when they may be more effective
bull It helps scientists learn more about the causes and development of AD
Slide 29
Physicians today use a number of tools to diagnose AD
bull a detailed patient history
bull information from family and friends
bull physical and neurological exams and lab tests
bull neuropsychological tests
bull imaging tools such as CT scan or magnetic resonance imaging (MRI) PET scans are used primarily for research purposes
CONTINUEDhelliphelliphelliphelliphelliphellip
Slide 30
Clinical trials are the primary way that researchers find out if a promising treatment is safe and effective
bull Trials examine approved drugs to see if they can be used for other purposes or look at experimental drugs
bull Participating in a trial means regular contact with the study team who can provide state-of-the-art AD care
Clinical Trials
Slide 31
Drugs used to treat mild to moderate AD symptoms include
bull Aricept
bull Exelon
bull Reminyl
An additional drug Namenda has been approved to treat symptoms of moderate to severe AD These drugs can help improve some patientsrsquo abilities to carry out activities up to a year or so but they do not stop or reverse AD
Scientists are also studying agents that someday may be useful in preventing AD For example they have experimented with a vaccine against AD Although the first clinical trial was stopped due to side effects in some participants valuable information was gathered
Treatments for AD
Slide 32
Researchers also are looking at other treatments including
bull cholesterol-lowering drugs called statins
bull anti-oxidants (vitamins) and folic acid
bull anti-inflammatory drugs
bull substances that prevent formation of beta-amyloid plaques
bull nerve growth factor to keep neurons healthy
Search for New Treatments
Slide 33
Who are the AD Caregiversbull Spouses ndash the largest group Most are older with
their own health problemsbull Daughters ndash the second largest group Called the
ldquosandwich generationrdquo many are married and raising children of their own Children may need extra support if a parentrsquos attention is focused on care giving
bull Grandchildren ndash may become major helpers
bull Daughters-in-law ndash the third largest group bull Sons ndash often focus on the financial legal and
business aspects of care giving bull Brothers and Sisters ndash many are older with
their own health problemsbull Other ndash friends neighbors members of the
faith community
Support for Caregivers
Slide 37
The NIA is studying how computers can provide information and support to family caregivers through
These features have become very popular among users because they reach many people at once are private and convenient and are available around the clock
bull computer-based bulletin boardsbull chat roomsbull Q amp A modulesbull medical advice forums
Slide 39
Technology and Care giving
One of the great mysteries of Alzheimerrsquos disease is why it largely strikes older adults
Research on how the brain changes normally with age is shedding light on this question For example scientists are learning how age-related changes in the brain may harm neurons and contribute to Alzheimerrsquos damage These age-related changes include atrophy (shrinking) of certain parts of the brain inflammation the production of unstable molecules called free radicals and mitochondrial dysfunction (a breakdown of energy production within a cell)
bull Generally it is diagnosed in people over 65 years of age although the less-prevalent early onset of Alzheimerrsquos can occur much earlier
bull In 2006 there were 266 million sufferers worldwide
bull Alzheimerrsquos is predicted to affect 1 in 85 people globally by 2050
Signs Of Normal Change vs Early Alzheimerrsquos Symptoms
Normal Early Alzheimerrsquos Disease
Canrsquot find your keys Routinely place important items in odd places such as keys in the fridge wallet in the dishwasher
Search for casual names and words
Forget names of family members and common objects or substitute words with inappropriate ones
Briefly forget conversation details
Frequently forget entire conversations
Feel the cold more Dress regardless of the weather wear several skirts on a warm day or shorts in a snow storm
Canrsquot find a recipe Canrsquot follow recipe directions
Forget to record a check Can no longer manage checkbook balance figures solve problems or think abstractly
Cancel a date with friends Withdraw from usual interests and activities sit in front of the TV for hours sleep far more than usual
Make an occasional wrong turn
Get lost in familiar places donrsquot remember how you got there or how to get home
Feel occasionally sad Experience rapid mood swings from tears to rage for no discernible reason
Life expectancyOn average people with Alzheimers disease live for around 8 to 10 years after they start to develop symptoms However this can vary considerably from person to person Some people with the condition will live longer than this but others will not
Alzheimers disease is not usually the actual cause of death but it is often a contributing factor For example a leading cause of death in people with Alzheimers disease is pneumonia (lung infection) which may go untreated because people with the condition often arent able to recognize that theyre ill or may not be able to tell someone they are feeling unwell
RESULTS 1203 subjects were resurveyed in 1997 and among them 124 new cases of dementia including 81 cases of AD were identified By computing the relative risk(RR) of psychosocial factors to the AD many psychosocial factors were found to be correlated with AD including blue collar occupation no job no reading or writing no taking community activities no gardening in leisure bad psychological feeling and lower education (RR gt 1) The items with high PARP gt 50 were not working no job retirement no taking community activities no reading or writing blue collar occupation and no gardening in leisure MMSE total score is a good predict for AD
Psychosocial risk factors of Alzheimers disease
Too much cake and chocolate could cause Alzheimers disease new research claims
Risk The study adds further evidence to links between diabetes and dementia
Eating too many chocolates cakes and other sugary treats could help trigger Alzheimerrsquos disease says new research
bullA study in mice found high levels of blood sugar rapidly increased rogue proteins in the body which combine and kill brain cells ultimately leading to dementia
CONTINUEDhelliphelliphelliphelliphellip
Green tea has also been proven to have beneficial effects when it comes to
Alzheimers(ALAMY)
Some famous books on Alzheimers
The 36-Hour Day fifth edition The 36-Hour by Nancy L Mace
Learning to Speak Alzheimers A Groundbrea
by Joanne Koenig Coste
The Validation Breakthrough Third Edition by Naomi Feil MSW
Alzheimers Disease What If There Was a Cu by Mary T Newport
A Caregivers Guide to Alzheimers Disease by Patricia R Callone
Creating Moments of Joy for the Person with by Jolene Brackey
Alzheimers Early Stages First Steps for F by Daniel Kuhn
Alzheimers Disease and Other Dementias - T by Nataly Rubinstein
Alzheimers For Dummies by Patricia B Smith
Some famous person died of Alzheimers
Fantasy author Sir Terry Pratchett dies at 66
Sir Terry Pratchett renowned fantasy author of more than 70 books has died at age 66
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Neurofibrillary Tangles
Neurons have an internal support structure partly made up of microtubules A protein called tau helps stabilize microtubules In AD tau changes causing microtubules to collapse and tau proteins clump together to form neurofibrillary tangles
AD and the Brain
Slide 18
The Changing Brain in Alzheimerrsquos Disease
No one knows what causes AD to begin but we do know a lot about what happens in the brain once AD takes hold
Pet Scan of Normal Brain
Pet Scan of Alzheimerrsquos Disease Brain
Slide 19
Causes for AD
bull AD develops when genetic lifestyle and environmental factors work together to cause the disease process to start
Slide 24
Genetic Studies
The two main types of AD are early-onset and late-onset
bull Early-onset AD is rare usually affecting people aged 30 to 60 and usually running in families Researchers have identified mutations in three genes that cause early-onset AD
bull Late-onset AD is more common It usually affects people over age 65 Researchers have identified
a gene that produces a protein called apolipoprotein E (ApoE) Scientists believe this protein is involved in the formation of beta-amyloid plaques
Slide 25
Environment and lifestyle factors
Diet ndash Diet can affect a persons risk of developing many types of illness including dementia A healthy and balanced diet that enables a person to maintain a normal body weight is likely to reduce the likelihood of developing high blood pressure or heart disease both of which put a person at greater risk of developing dementia
Smoking ndash Smoking has an extremely harmful effect on the heart lungs and vascular system including the blood vessels in the brain This significantly increases the risk of developing dementia
Alcohol ndash Drinking above recommended levels of alcohol significantly increases the risk of developing dementias such as Alzheimers and vascular dementia However research suggests that light-to-moderate amounts of alcohol may protect the brain against dementia and keep the heart and vascular system healthy
Social activity ndash Research suggests that people who are more socially active have a slightly reduced risk of developing dementia
Mental activity ndash Research suggests that people who take part in mental activities (such as reading learning and doing puzzles) are less likely to develop dementia compared with those who do not engage in these activities
Continuedhelliphelliphelliphelliphelliphellip
Diagnosing for AD
Diagnosing AD
Experienced physicians in specialized AD centers can now diagnose AD with up to 90 percent accuracy Early diagnosis has advantages
bull Doctors can rule out other conditions that may cause dementia
bull If it is AD families have more time to plan for the future
bull Treatments can start earlier when they may be more effective
bull It helps scientists learn more about the causes and development of AD
Slide 29
Physicians today use a number of tools to diagnose AD
bull a detailed patient history
bull information from family and friends
bull physical and neurological exams and lab tests
bull neuropsychological tests
bull imaging tools such as CT scan or magnetic resonance imaging (MRI) PET scans are used primarily for research purposes
CONTINUEDhelliphelliphelliphelliphelliphellip
Slide 30
Clinical trials are the primary way that researchers find out if a promising treatment is safe and effective
bull Trials examine approved drugs to see if they can be used for other purposes or look at experimental drugs
bull Participating in a trial means regular contact with the study team who can provide state-of-the-art AD care
Clinical Trials
Slide 31
Drugs used to treat mild to moderate AD symptoms include
bull Aricept
bull Exelon
bull Reminyl
An additional drug Namenda has been approved to treat symptoms of moderate to severe AD These drugs can help improve some patientsrsquo abilities to carry out activities up to a year or so but they do not stop or reverse AD
Scientists are also studying agents that someday may be useful in preventing AD For example they have experimented with a vaccine against AD Although the first clinical trial was stopped due to side effects in some participants valuable information was gathered
Treatments for AD
Slide 32
Researchers also are looking at other treatments including
bull cholesterol-lowering drugs called statins
bull anti-oxidants (vitamins) and folic acid
bull anti-inflammatory drugs
bull substances that prevent formation of beta-amyloid plaques
bull nerve growth factor to keep neurons healthy
Search for New Treatments
Slide 33
Who are the AD Caregiversbull Spouses ndash the largest group Most are older with
their own health problemsbull Daughters ndash the second largest group Called the
ldquosandwich generationrdquo many are married and raising children of their own Children may need extra support if a parentrsquos attention is focused on care giving
bull Grandchildren ndash may become major helpers
bull Daughters-in-law ndash the third largest group bull Sons ndash often focus on the financial legal and
business aspects of care giving bull Brothers and Sisters ndash many are older with
their own health problemsbull Other ndash friends neighbors members of the
faith community
Support for Caregivers
Slide 37
The NIA is studying how computers can provide information and support to family caregivers through
These features have become very popular among users because they reach many people at once are private and convenient and are available around the clock
bull computer-based bulletin boardsbull chat roomsbull Q amp A modulesbull medical advice forums
Slide 39
Technology and Care giving
One of the great mysteries of Alzheimerrsquos disease is why it largely strikes older adults
Research on how the brain changes normally with age is shedding light on this question For example scientists are learning how age-related changes in the brain may harm neurons and contribute to Alzheimerrsquos damage These age-related changes include atrophy (shrinking) of certain parts of the brain inflammation the production of unstable molecules called free radicals and mitochondrial dysfunction (a breakdown of energy production within a cell)
bull Generally it is diagnosed in people over 65 years of age although the less-prevalent early onset of Alzheimerrsquos can occur much earlier
bull In 2006 there were 266 million sufferers worldwide
bull Alzheimerrsquos is predicted to affect 1 in 85 people globally by 2050
Signs Of Normal Change vs Early Alzheimerrsquos Symptoms
Normal Early Alzheimerrsquos Disease
Canrsquot find your keys Routinely place important items in odd places such as keys in the fridge wallet in the dishwasher
Search for casual names and words
Forget names of family members and common objects or substitute words with inappropriate ones
Briefly forget conversation details
Frequently forget entire conversations
Feel the cold more Dress regardless of the weather wear several skirts on a warm day or shorts in a snow storm
Canrsquot find a recipe Canrsquot follow recipe directions
Forget to record a check Can no longer manage checkbook balance figures solve problems or think abstractly
Cancel a date with friends Withdraw from usual interests and activities sit in front of the TV for hours sleep far more than usual
Make an occasional wrong turn
Get lost in familiar places donrsquot remember how you got there or how to get home
Feel occasionally sad Experience rapid mood swings from tears to rage for no discernible reason
Life expectancyOn average people with Alzheimers disease live for around 8 to 10 years after they start to develop symptoms However this can vary considerably from person to person Some people with the condition will live longer than this but others will not
Alzheimers disease is not usually the actual cause of death but it is often a contributing factor For example a leading cause of death in people with Alzheimers disease is pneumonia (lung infection) which may go untreated because people with the condition often arent able to recognize that theyre ill or may not be able to tell someone they are feeling unwell
RESULTS 1203 subjects were resurveyed in 1997 and among them 124 new cases of dementia including 81 cases of AD were identified By computing the relative risk(RR) of psychosocial factors to the AD many psychosocial factors were found to be correlated with AD including blue collar occupation no job no reading or writing no taking community activities no gardening in leisure bad psychological feeling and lower education (RR gt 1) The items with high PARP gt 50 were not working no job retirement no taking community activities no reading or writing blue collar occupation and no gardening in leisure MMSE total score is a good predict for AD
Psychosocial risk factors of Alzheimers disease
Too much cake and chocolate could cause Alzheimers disease new research claims
Risk The study adds further evidence to links between diabetes and dementia
Eating too many chocolates cakes and other sugary treats could help trigger Alzheimerrsquos disease says new research
bullA study in mice found high levels of blood sugar rapidly increased rogue proteins in the body which combine and kill brain cells ultimately leading to dementia
CONTINUEDhelliphelliphelliphelliphellip
Green tea has also been proven to have beneficial effects when it comes to
Alzheimers(ALAMY)
Some famous books on Alzheimers
The 36-Hour Day fifth edition The 36-Hour by Nancy L Mace
Learning to Speak Alzheimers A Groundbrea
by Joanne Koenig Coste
The Validation Breakthrough Third Edition by Naomi Feil MSW
Alzheimers Disease What If There Was a Cu by Mary T Newport
A Caregivers Guide to Alzheimers Disease by Patricia R Callone
Creating Moments of Joy for the Person with by Jolene Brackey
Alzheimers Early Stages First Steps for F by Daniel Kuhn
Alzheimers Disease and Other Dementias - T by Nataly Rubinstein
Alzheimers For Dummies by Patricia B Smith
Some famous person died of Alzheimers
Fantasy author Sir Terry Pratchett dies at 66
Sir Terry Pratchett renowned fantasy author of more than 70 books has died at age 66
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
The Changing Brain in Alzheimerrsquos Disease
No one knows what causes AD to begin but we do know a lot about what happens in the brain once AD takes hold
Pet Scan of Normal Brain
Pet Scan of Alzheimerrsquos Disease Brain
Slide 19
Causes for AD
bull AD develops when genetic lifestyle and environmental factors work together to cause the disease process to start
Slide 24
Genetic Studies
The two main types of AD are early-onset and late-onset
bull Early-onset AD is rare usually affecting people aged 30 to 60 and usually running in families Researchers have identified mutations in three genes that cause early-onset AD
bull Late-onset AD is more common It usually affects people over age 65 Researchers have identified
a gene that produces a protein called apolipoprotein E (ApoE) Scientists believe this protein is involved in the formation of beta-amyloid plaques
Slide 25
Environment and lifestyle factors
Diet ndash Diet can affect a persons risk of developing many types of illness including dementia A healthy and balanced diet that enables a person to maintain a normal body weight is likely to reduce the likelihood of developing high blood pressure or heart disease both of which put a person at greater risk of developing dementia
Smoking ndash Smoking has an extremely harmful effect on the heart lungs and vascular system including the blood vessels in the brain This significantly increases the risk of developing dementia
Alcohol ndash Drinking above recommended levels of alcohol significantly increases the risk of developing dementias such as Alzheimers and vascular dementia However research suggests that light-to-moderate amounts of alcohol may protect the brain against dementia and keep the heart and vascular system healthy
Social activity ndash Research suggests that people who are more socially active have a slightly reduced risk of developing dementia
Mental activity ndash Research suggests that people who take part in mental activities (such as reading learning and doing puzzles) are less likely to develop dementia compared with those who do not engage in these activities
Continuedhelliphelliphelliphelliphelliphellip
Diagnosing for AD
Diagnosing AD
Experienced physicians in specialized AD centers can now diagnose AD with up to 90 percent accuracy Early diagnosis has advantages
bull Doctors can rule out other conditions that may cause dementia
bull If it is AD families have more time to plan for the future
bull Treatments can start earlier when they may be more effective
bull It helps scientists learn more about the causes and development of AD
Slide 29
Physicians today use a number of tools to diagnose AD
bull a detailed patient history
bull information from family and friends
bull physical and neurological exams and lab tests
bull neuropsychological tests
bull imaging tools such as CT scan or magnetic resonance imaging (MRI) PET scans are used primarily for research purposes
CONTINUEDhelliphelliphelliphelliphelliphellip
Slide 30
Clinical trials are the primary way that researchers find out if a promising treatment is safe and effective
bull Trials examine approved drugs to see if they can be used for other purposes or look at experimental drugs
bull Participating in a trial means regular contact with the study team who can provide state-of-the-art AD care
Clinical Trials
Slide 31
Drugs used to treat mild to moderate AD symptoms include
bull Aricept
bull Exelon
bull Reminyl
An additional drug Namenda has been approved to treat symptoms of moderate to severe AD These drugs can help improve some patientsrsquo abilities to carry out activities up to a year or so but they do not stop or reverse AD
Scientists are also studying agents that someday may be useful in preventing AD For example they have experimented with a vaccine against AD Although the first clinical trial was stopped due to side effects in some participants valuable information was gathered
Treatments for AD
Slide 32
Researchers also are looking at other treatments including
bull cholesterol-lowering drugs called statins
bull anti-oxidants (vitamins) and folic acid
bull anti-inflammatory drugs
bull substances that prevent formation of beta-amyloid plaques
bull nerve growth factor to keep neurons healthy
Search for New Treatments
Slide 33
Who are the AD Caregiversbull Spouses ndash the largest group Most are older with
their own health problemsbull Daughters ndash the second largest group Called the
ldquosandwich generationrdquo many are married and raising children of their own Children may need extra support if a parentrsquos attention is focused on care giving
bull Grandchildren ndash may become major helpers
bull Daughters-in-law ndash the third largest group bull Sons ndash often focus on the financial legal and
business aspects of care giving bull Brothers and Sisters ndash many are older with
their own health problemsbull Other ndash friends neighbors members of the
faith community
Support for Caregivers
Slide 37
The NIA is studying how computers can provide information and support to family caregivers through
These features have become very popular among users because they reach many people at once are private and convenient and are available around the clock
bull computer-based bulletin boardsbull chat roomsbull Q amp A modulesbull medical advice forums
Slide 39
Technology and Care giving
One of the great mysteries of Alzheimerrsquos disease is why it largely strikes older adults
Research on how the brain changes normally with age is shedding light on this question For example scientists are learning how age-related changes in the brain may harm neurons and contribute to Alzheimerrsquos damage These age-related changes include atrophy (shrinking) of certain parts of the brain inflammation the production of unstable molecules called free radicals and mitochondrial dysfunction (a breakdown of energy production within a cell)
bull Generally it is diagnosed in people over 65 years of age although the less-prevalent early onset of Alzheimerrsquos can occur much earlier
bull In 2006 there were 266 million sufferers worldwide
bull Alzheimerrsquos is predicted to affect 1 in 85 people globally by 2050
Signs Of Normal Change vs Early Alzheimerrsquos Symptoms
Normal Early Alzheimerrsquos Disease
Canrsquot find your keys Routinely place important items in odd places such as keys in the fridge wallet in the dishwasher
Search for casual names and words
Forget names of family members and common objects or substitute words with inappropriate ones
Briefly forget conversation details
Frequently forget entire conversations
Feel the cold more Dress regardless of the weather wear several skirts on a warm day or shorts in a snow storm
Canrsquot find a recipe Canrsquot follow recipe directions
Forget to record a check Can no longer manage checkbook balance figures solve problems or think abstractly
Cancel a date with friends Withdraw from usual interests and activities sit in front of the TV for hours sleep far more than usual
Make an occasional wrong turn
Get lost in familiar places donrsquot remember how you got there or how to get home
Feel occasionally sad Experience rapid mood swings from tears to rage for no discernible reason
Life expectancyOn average people with Alzheimers disease live for around 8 to 10 years after they start to develop symptoms However this can vary considerably from person to person Some people with the condition will live longer than this but others will not
Alzheimers disease is not usually the actual cause of death but it is often a contributing factor For example a leading cause of death in people with Alzheimers disease is pneumonia (lung infection) which may go untreated because people with the condition often arent able to recognize that theyre ill or may not be able to tell someone they are feeling unwell
RESULTS 1203 subjects were resurveyed in 1997 and among them 124 new cases of dementia including 81 cases of AD were identified By computing the relative risk(RR) of psychosocial factors to the AD many psychosocial factors were found to be correlated with AD including blue collar occupation no job no reading or writing no taking community activities no gardening in leisure bad psychological feeling and lower education (RR gt 1) The items with high PARP gt 50 were not working no job retirement no taking community activities no reading or writing blue collar occupation and no gardening in leisure MMSE total score is a good predict for AD
Psychosocial risk factors of Alzheimers disease
Too much cake and chocolate could cause Alzheimers disease new research claims
Risk The study adds further evidence to links between diabetes and dementia
Eating too many chocolates cakes and other sugary treats could help trigger Alzheimerrsquos disease says new research
bullA study in mice found high levels of blood sugar rapidly increased rogue proteins in the body which combine and kill brain cells ultimately leading to dementia
CONTINUEDhelliphelliphelliphelliphellip
Green tea has also been proven to have beneficial effects when it comes to
Alzheimers(ALAMY)
Some famous books on Alzheimers
The 36-Hour Day fifth edition The 36-Hour by Nancy L Mace
Learning to Speak Alzheimers A Groundbrea
by Joanne Koenig Coste
The Validation Breakthrough Third Edition by Naomi Feil MSW
Alzheimers Disease What If There Was a Cu by Mary T Newport
A Caregivers Guide to Alzheimers Disease by Patricia R Callone
Creating Moments of Joy for the Person with by Jolene Brackey
Alzheimers Early Stages First Steps for F by Daniel Kuhn
Alzheimers Disease and Other Dementias - T by Nataly Rubinstein
Alzheimers For Dummies by Patricia B Smith
Some famous person died of Alzheimers
Fantasy author Sir Terry Pratchett dies at 66
Sir Terry Pratchett renowned fantasy author of more than 70 books has died at age 66
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Causes for AD
bull AD develops when genetic lifestyle and environmental factors work together to cause the disease process to start
Slide 24
Genetic Studies
The two main types of AD are early-onset and late-onset
bull Early-onset AD is rare usually affecting people aged 30 to 60 and usually running in families Researchers have identified mutations in three genes that cause early-onset AD
bull Late-onset AD is more common It usually affects people over age 65 Researchers have identified
a gene that produces a protein called apolipoprotein E (ApoE) Scientists believe this protein is involved in the formation of beta-amyloid plaques
Slide 25
Environment and lifestyle factors
Diet ndash Diet can affect a persons risk of developing many types of illness including dementia A healthy and balanced diet that enables a person to maintain a normal body weight is likely to reduce the likelihood of developing high blood pressure or heart disease both of which put a person at greater risk of developing dementia
Smoking ndash Smoking has an extremely harmful effect on the heart lungs and vascular system including the blood vessels in the brain This significantly increases the risk of developing dementia
Alcohol ndash Drinking above recommended levels of alcohol significantly increases the risk of developing dementias such as Alzheimers and vascular dementia However research suggests that light-to-moderate amounts of alcohol may protect the brain against dementia and keep the heart and vascular system healthy
Social activity ndash Research suggests that people who are more socially active have a slightly reduced risk of developing dementia
Mental activity ndash Research suggests that people who take part in mental activities (such as reading learning and doing puzzles) are less likely to develop dementia compared with those who do not engage in these activities
Continuedhelliphelliphelliphelliphelliphellip
Diagnosing for AD
Diagnosing AD
Experienced physicians in specialized AD centers can now diagnose AD with up to 90 percent accuracy Early diagnosis has advantages
bull Doctors can rule out other conditions that may cause dementia
bull If it is AD families have more time to plan for the future
bull Treatments can start earlier when they may be more effective
bull It helps scientists learn more about the causes and development of AD
Slide 29
Physicians today use a number of tools to diagnose AD
bull a detailed patient history
bull information from family and friends
bull physical and neurological exams and lab tests
bull neuropsychological tests
bull imaging tools such as CT scan or magnetic resonance imaging (MRI) PET scans are used primarily for research purposes
CONTINUEDhelliphelliphelliphelliphelliphellip
Slide 30
Clinical trials are the primary way that researchers find out if a promising treatment is safe and effective
bull Trials examine approved drugs to see if they can be used for other purposes or look at experimental drugs
bull Participating in a trial means regular contact with the study team who can provide state-of-the-art AD care
Clinical Trials
Slide 31
Drugs used to treat mild to moderate AD symptoms include
bull Aricept
bull Exelon
bull Reminyl
An additional drug Namenda has been approved to treat symptoms of moderate to severe AD These drugs can help improve some patientsrsquo abilities to carry out activities up to a year or so but they do not stop or reverse AD
Scientists are also studying agents that someday may be useful in preventing AD For example they have experimented with a vaccine against AD Although the first clinical trial was stopped due to side effects in some participants valuable information was gathered
Treatments for AD
Slide 32
Researchers also are looking at other treatments including
bull cholesterol-lowering drugs called statins
bull anti-oxidants (vitamins) and folic acid
bull anti-inflammatory drugs
bull substances that prevent formation of beta-amyloid plaques
bull nerve growth factor to keep neurons healthy
Search for New Treatments
Slide 33
Who are the AD Caregiversbull Spouses ndash the largest group Most are older with
their own health problemsbull Daughters ndash the second largest group Called the
ldquosandwich generationrdquo many are married and raising children of their own Children may need extra support if a parentrsquos attention is focused on care giving
bull Grandchildren ndash may become major helpers
bull Daughters-in-law ndash the third largest group bull Sons ndash often focus on the financial legal and
business aspects of care giving bull Brothers and Sisters ndash many are older with
their own health problemsbull Other ndash friends neighbors members of the
faith community
Support for Caregivers
Slide 37
The NIA is studying how computers can provide information and support to family caregivers through
These features have become very popular among users because they reach many people at once are private and convenient and are available around the clock
bull computer-based bulletin boardsbull chat roomsbull Q amp A modulesbull medical advice forums
Slide 39
Technology and Care giving
One of the great mysteries of Alzheimerrsquos disease is why it largely strikes older adults
Research on how the brain changes normally with age is shedding light on this question For example scientists are learning how age-related changes in the brain may harm neurons and contribute to Alzheimerrsquos damage These age-related changes include atrophy (shrinking) of certain parts of the brain inflammation the production of unstable molecules called free radicals and mitochondrial dysfunction (a breakdown of energy production within a cell)
bull Generally it is diagnosed in people over 65 years of age although the less-prevalent early onset of Alzheimerrsquos can occur much earlier
bull In 2006 there were 266 million sufferers worldwide
bull Alzheimerrsquos is predicted to affect 1 in 85 people globally by 2050
Signs Of Normal Change vs Early Alzheimerrsquos Symptoms
Normal Early Alzheimerrsquos Disease
Canrsquot find your keys Routinely place important items in odd places such as keys in the fridge wallet in the dishwasher
Search for casual names and words
Forget names of family members and common objects or substitute words with inappropriate ones
Briefly forget conversation details
Frequently forget entire conversations
Feel the cold more Dress regardless of the weather wear several skirts on a warm day or shorts in a snow storm
Canrsquot find a recipe Canrsquot follow recipe directions
Forget to record a check Can no longer manage checkbook balance figures solve problems or think abstractly
Cancel a date with friends Withdraw from usual interests and activities sit in front of the TV for hours sleep far more than usual
Make an occasional wrong turn
Get lost in familiar places donrsquot remember how you got there or how to get home
Feel occasionally sad Experience rapid mood swings from tears to rage for no discernible reason
Life expectancyOn average people with Alzheimers disease live for around 8 to 10 years after they start to develop symptoms However this can vary considerably from person to person Some people with the condition will live longer than this but others will not
Alzheimers disease is not usually the actual cause of death but it is often a contributing factor For example a leading cause of death in people with Alzheimers disease is pneumonia (lung infection) which may go untreated because people with the condition often arent able to recognize that theyre ill or may not be able to tell someone they are feeling unwell
RESULTS 1203 subjects were resurveyed in 1997 and among them 124 new cases of dementia including 81 cases of AD were identified By computing the relative risk(RR) of psychosocial factors to the AD many psychosocial factors were found to be correlated with AD including blue collar occupation no job no reading or writing no taking community activities no gardening in leisure bad psychological feeling and lower education (RR gt 1) The items with high PARP gt 50 were not working no job retirement no taking community activities no reading or writing blue collar occupation and no gardening in leisure MMSE total score is a good predict for AD
Psychosocial risk factors of Alzheimers disease
Too much cake and chocolate could cause Alzheimers disease new research claims
Risk The study adds further evidence to links between diabetes and dementia
Eating too many chocolates cakes and other sugary treats could help trigger Alzheimerrsquos disease says new research
bullA study in mice found high levels of blood sugar rapidly increased rogue proteins in the body which combine and kill brain cells ultimately leading to dementia
CONTINUEDhelliphelliphelliphelliphellip
Green tea has also been proven to have beneficial effects when it comes to
Alzheimers(ALAMY)
Some famous books on Alzheimers
The 36-Hour Day fifth edition The 36-Hour by Nancy L Mace
Learning to Speak Alzheimers A Groundbrea
by Joanne Koenig Coste
The Validation Breakthrough Third Edition by Naomi Feil MSW
Alzheimers Disease What If There Was a Cu by Mary T Newport
A Caregivers Guide to Alzheimers Disease by Patricia R Callone
Creating Moments of Joy for the Person with by Jolene Brackey
Alzheimers Early Stages First Steps for F by Daniel Kuhn
Alzheimers Disease and Other Dementias - T by Nataly Rubinstein
Alzheimers For Dummies by Patricia B Smith
Some famous person died of Alzheimers
Fantasy author Sir Terry Pratchett dies at 66
Sir Terry Pratchett renowned fantasy author of more than 70 books has died at age 66
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Genetic Studies
The two main types of AD are early-onset and late-onset
bull Early-onset AD is rare usually affecting people aged 30 to 60 and usually running in families Researchers have identified mutations in three genes that cause early-onset AD
bull Late-onset AD is more common It usually affects people over age 65 Researchers have identified
a gene that produces a protein called apolipoprotein E (ApoE) Scientists believe this protein is involved in the formation of beta-amyloid plaques
Slide 25
Environment and lifestyle factors
Diet ndash Diet can affect a persons risk of developing many types of illness including dementia A healthy and balanced diet that enables a person to maintain a normal body weight is likely to reduce the likelihood of developing high blood pressure or heart disease both of which put a person at greater risk of developing dementia
Smoking ndash Smoking has an extremely harmful effect on the heart lungs and vascular system including the blood vessels in the brain This significantly increases the risk of developing dementia
Alcohol ndash Drinking above recommended levels of alcohol significantly increases the risk of developing dementias such as Alzheimers and vascular dementia However research suggests that light-to-moderate amounts of alcohol may protect the brain against dementia and keep the heart and vascular system healthy
Social activity ndash Research suggests that people who are more socially active have a slightly reduced risk of developing dementia
Mental activity ndash Research suggests that people who take part in mental activities (such as reading learning and doing puzzles) are less likely to develop dementia compared with those who do not engage in these activities
Continuedhelliphelliphelliphelliphelliphellip
Diagnosing for AD
Diagnosing AD
Experienced physicians in specialized AD centers can now diagnose AD with up to 90 percent accuracy Early diagnosis has advantages
bull Doctors can rule out other conditions that may cause dementia
bull If it is AD families have more time to plan for the future
bull Treatments can start earlier when they may be more effective
bull It helps scientists learn more about the causes and development of AD
Slide 29
Physicians today use a number of tools to diagnose AD
bull a detailed patient history
bull information from family and friends
bull physical and neurological exams and lab tests
bull neuropsychological tests
bull imaging tools such as CT scan or magnetic resonance imaging (MRI) PET scans are used primarily for research purposes
CONTINUEDhelliphelliphelliphelliphelliphellip
Slide 30
Clinical trials are the primary way that researchers find out if a promising treatment is safe and effective
bull Trials examine approved drugs to see if they can be used for other purposes or look at experimental drugs
bull Participating in a trial means regular contact with the study team who can provide state-of-the-art AD care
Clinical Trials
Slide 31
Drugs used to treat mild to moderate AD symptoms include
bull Aricept
bull Exelon
bull Reminyl
An additional drug Namenda has been approved to treat symptoms of moderate to severe AD These drugs can help improve some patientsrsquo abilities to carry out activities up to a year or so but they do not stop or reverse AD
Scientists are also studying agents that someday may be useful in preventing AD For example they have experimented with a vaccine against AD Although the first clinical trial was stopped due to side effects in some participants valuable information was gathered
Treatments for AD
Slide 32
Researchers also are looking at other treatments including
bull cholesterol-lowering drugs called statins
bull anti-oxidants (vitamins) and folic acid
bull anti-inflammatory drugs
bull substances that prevent formation of beta-amyloid plaques
bull nerve growth factor to keep neurons healthy
Search for New Treatments
Slide 33
Who are the AD Caregiversbull Spouses ndash the largest group Most are older with
their own health problemsbull Daughters ndash the second largest group Called the
ldquosandwich generationrdquo many are married and raising children of their own Children may need extra support if a parentrsquos attention is focused on care giving
bull Grandchildren ndash may become major helpers
bull Daughters-in-law ndash the third largest group bull Sons ndash often focus on the financial legal and
business aspects of care giving bull Brothers and Sisters ndash many are older with
their own health problemsbull Other ndash friends neighbors members of the
faith community
Support for Caregivers
Slide 37
The NIA is studying how computers can provide information and support to family caregivers through
These features have become very popular among users because they reach many people at once are private and convenient and are available around the clock
bull computer-based bulletin boardsbull chat roomsbull Q amp A modulesbull medical advice forums
Slide 39
Technology and Care giving
One of the great mysteries of Alzheimerrsquos disease is why it largely strikes older adults
Research on how the brain changes normally with age is shedding light on this question For example scientists are learning how age-related changes in the brain may harm neurons and contribute to Alzheimerrsquos damage These age-related changes include atrophy (shrinking) of certain parts of the brain inflammation the production of unstable molecules called free radicals and mitochondrial dysfunction (a breakdown of energy production within a cell)
bull Generally it is diagnosed in people over 65 years of age although the less-prevalent early onset of Alzheimerrsquos can occur much earlier
bull In 2006 there were 266 million sufferers worldwide
bull Alzheimerrsquos is predicted to affect 1 in 85 people globally by 2050
Signs Of Normal Change vs Early Alzheimerrsquos Symptoms
Normal Early Alzheimerrsquos Disease
Canrsquot find your keys Routinely place important items in odd places such as keys in the fridge wallet in the dishwasher
Search for casual names and words
Forget names of family members and common objects or substitute words with inappropriate ones
Briefly forget conversation details
Frequently forget entire conversations
Feel the cold more Dress regardless of the weather wear several skirts on a warm day or shorts in a snow storm
Canrsquot find a recipe Canrsquot follow recipe directions
Forget to record a check Can no longer manage checkbook balance figures solve problems or think abstractly
Cancel a date with friends Withdraw from usual interests and activities sit in front of the TV for hours sleep far more than usual
Make an occasional wrong turn
Get lost in familiar places donrsquot remember how you got there or how to get home
Feel occasionally sad Experience rapid mood swings from tears to rage for no discernible reason
Life expectancyOn average people with Alzheimers disease live for around 8 to 10 years after they start to develop symptoms However this can vary considerably from person to person Some people with the condition will live longer than this but others will not
Alzheimers disease is not usually the actual cause of death but it is often a contributing factor For example a leading cause of death in people with Alzheimers disease is pneumonia (lung infection) which may go untreated because people with the condition often arent able to recognize that theyre ill or may not be able to tell someone they are feeling unwell
RESULTS 1203 subjects were resurveyed in 1997 and among them 124 new cases of dementia including 81 cases of AD were identified By computing the relative risk(RR) of psychosocial factors to the AD many psychosocial factors were found to be correlated with AD including blue collar occupation no job no reading or writing no taking community activities no gardening in leisure bad psychological feeling and lower education (RR gt 1) The items with high PARP gt 50 were not working no job retirement no taking community activities no reading or writing blue collar occupation and no gardening in leisure MMSE total score is a good predict for AD
Psychosocial risk factors of Alzheimers disease
Too much cake and chocolate could cause Alzheimers disease new research claims
Risk The study adds further evidence to links between diabetes and dementia
Eating too many chocolates cakes and other sugary treats could help trigger Alzheimerrsquos disease says new research
bullA study in mice found high levels of blood sugar rapidly increased rogue proteins in the body which combine and kill brain cells ultimately leading to dementia
CONTINUEDhelliphelliphelliphelliphellip
Green tea has also been proven to have beneficial effects when it comes to
Alzheimers(ALAMY)
Some famous books on Alzheimers
The 36-Hour Day fifth edition The 36-Hour by Nancy L Mace
Learning to Speak Alzheimers A Groundbrea
by Joanne Koenig Coste
The Validation Breakthrough Third Edition by Naomi Feil MSW
Alzheimers Disease What If There Was a Cu by Mary T Newport
A Caregivers Guide to Alzheimers Disease by Patricia R Callone
Creating Moments of Joy for the Person with by Jolene Brackey
Alzheimers Early Stages First Steps for F by Daniel Kuhn
Alzheimers Disease and Other Dementias - T by Nataly Rubinstein
Alzheimers For Dummies by Patricia B Smith
Some famous person died of Alzheimers
Fantasy author Sir Terry Pratchett dies at 66
Sir Terry Pratchett renowned fantasy author of more than 70 books has died at age 66
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Environment and lifestyle factors
Diet ndash Diet can affect a persons risk of developing many types of illness including dementia A healthy and balanced diet that enables a person to maintain a normal body weight is likely to reduce the likelihood of developing high blood pressure or heart disease both of which put a person at greater risk of developing dementia
Smoking ndash Smoking has an extremely harmful effect on the heart lungs and vascular system including the blood vessels in the brain This significantly increases the risk of developing dementia
Alcohol ndash Drinking above recommended levels of alcohol significantly increases the risk of developing dementias such as Alzheimers and vascular dementia However research suggests that light-to-moderate amounts of alcohol may protect the brain against dementia and keep the heart and vascular system healthy
Social activity ndash Research suggests that people who are more socially active have a slightly reduced risk of developing dementia
Mental activity ndash Research suggests that people who take part in mental activities (such as reading learning and doing puzzles) are less likely to develop dementia compared with those who do not engage in these activities
Continuedhelliphelliphelliphelliphelliphellip
Diagnosing for AD
Diagnosing AD
Experienced physicians in specialized AD centers can now diagnose AD with up to 90 percent accuracy Early diagnosis has advantages
bull Doctors can rule out other conditions that may cause dementia
bull If it is AD families have more time to plan for the future
bull Treatments can start earlier when they may be more effective
bull It helps scientists learn more about the causes and development of AD
Slide 29
Physicians today use a number of tools to diagnose AD
bull a detailed patient history
bull information from family and friends
bull physical and neurological exams and lab tests
bull neuropsychological tests
bull imaging tools such as CT scan or magnetic resonance imaging (MRI) PET scans are used primarily for research purposes
CONTINUEDhelliphelliphelliphelliphelliphellip
Slide 30
Clinical trials are the primary way that researchers find out if a promising treatment is safe and effective
bull Trials examine approved drugs to see if they can be used for other purposes or look at experimental drugs
bull Participating in a trial means regular contact with the study team who can provide state-of-the-art AD care
Clinical Trials
Slide 31
Drugs used to treat mild to moderate AD symptoms include
bull Aricept
bull Exelon
bull Reminyl
An additional drug Namenda has been approved to treat symptoms of moderate to severe AD These drugs can help improve some patientsrsquo abilities to carry out activities up to a year or so but they do not stop or reverse AD
Scientists are also studying agents that someday may be useful in preventing AD For example they have experimented with a vaccine against AD Although the first clinical trial was stopped due to side effects in some participants valuable information was gathered
Treatments for AD
Slide 32
Researchers also are looking at other treatments including
bull cholesterol-lowering drugs called statins
bull anti-oxidants (vitamins) and folic acid
bull anti-inflammatory drugs
bull substances that prevent formation of beta-amyloid plaques
bull nerve growth factor to keep neurons healthy
Search for New Treatments
Slide 33
Who are the AD Caregiversbull Spouses ndash the largest group Most are older with
their own health problemsbull Daughters ndash the second largest group Called the
ldquosandwich generationrdquo many are married and raising children of their own Children may need extra support if a parentrsquos attention is focused on care giving
bull Grandchildren ndash may become major helpers
bull Daughters-in-law ndash the third largest group bull Sons ndash often focus on the financial legal and
business aspects of care giving bull Brothers and Sisters ndash many are older with
their own health problemsbull Other ndash friends neighbors members of the
faith community
Support for Caregivers
Slide 37
The NIA is studying how computers can provide information and support to family caregivers through
These features have become very popular among users because they reach many people at once are private and convenient and are available around the clock
bull computer-based bulletin boardsbull chat roomsbull Q amp A modulesbull medical advice forums
Slide 39
Technology and Care giving
One of the great mysteries of Alzheimerrsquos disease is why it largely strikes older adults
Research on how the brain changes normally with age is shedding light on this question For example scientists are learning how age-related changes in the brain may harm neurons and contribute to Alzheimerrsquos damage These age-related changes include atrophy (shrinking) of certain parts of the brain inflammation the production of unstable molecules called free radicals and mitochondrial dysfunction (a breakdown of energy production within a cell)
bull Generally it is diagnosed in people over 65 years of age although the less-prevalent early onset of Alzheimerrsquos can occur much earlier
bull In 2006 there were 266 million sufferers worldwide
bull Alzheimerrsquos is predicted to affect 1 in 85 people globally by 2050
Signs Of Normal Change vs Early Alzheimerrsquos Symptoms
Normal Early Alzheimerrsquos Disease
Canrsquot find your keys Routinely place important items in odd places such as keys in the fridge wallet in the dishwasher
Search for casual names and words
Forget names of family members and common objects or substitute words with inappropriate ones
Briefly forget conversation details
Frequently forget entire conversations
Feel the cold more Dress regardless of the weather wear several skirts on a warm day or shorts in a snow storm
Canrsquot find a recipe Canrsquot follow recipe directions
Forget to record a check Can no longer manage checkbook balance figures solve problems or think abstractly
Cancel a date with friends Withdraw from usual interests and activities sit in front of the TV for hours sleep far more than usual
Make an occasional wrong turn
Get lost in familiar places donrsquot remember how you got there or how to get home
Feel occasionally sad Experience rapid mood swings from tears to rage for no discernible reason
Life expectancyOn average people with Alzheimers disease live for around 8 to 10 years after they start to develop symptoms However this can vary considerably from person to person Some people with the condition will live longer than this but others will not
Alzheimers disease is not usually the actual cause of death but it is often a contributing factor For example a leading cause of death in people with Alzheimers disease is pneumonia (lung infection) which may go untreated because people with the condition often arent able to recognize that theyre ill or may not be able to tell someone they are feeling unwell
RESULTS 1203 subjects were resurveyed in 1997 and among them 124 new cases of dementia including 81 cases of AD were identified By computing the relative risk(RR) of psychosocial factors to the AD many psychosocial factors were found to be correlated with AD including blue collar occupation no job no reading or writing no taking community activities no gardening in leisure bad psychological feeling and lower education (RR gt 1) The items with high PARP gt 50 were not working no job retirement no taking community activities no reading or writing blue collar occupation and no gardening in leisure MMSE total score is a good predict for AD
Psychosocial risk factors of Alzheimers disease
Too much cake and chocolate could cause Alzheimers disease new research claims
Risk The study adds further evidence to links between diabetes and dementia
Eating too many chocolates cakes and other sugary treats could help trigger Alzheimerrsquos disease says new research
bullA study in mice found high levels of blood sugar rapidly increased rogue proteins in the body which combine and kill brain cells ultimately leading to dementia
CONTINUEDhelliphelliphelliphelliphellip
Green tea has also been proven to have beneficial effects when it comes to
Alzheimers(ALAMY)
Some famous books on Alzheimers
The 36-Hour Day fifth edition The 36-Hour by Nancy L Mace
Learning to Speak Alzheimers A Groundbrea
by Joanne Koenig Coste
The Validation Breakthrough Third Edition by Naomi Feil MSW
Alzheimers Disease What If There Was a Cu by Mary T Newport
A Caregivers Guide to Alzheimers Disease by Patricia R Callone
Creating Moments of Joy for the Person with by Jolene Brackey
Alzheimers Early Stages First Steps for F by Daniel Kuhn
Alzheimers Disease and Other Dementias - T by Nataly Rubinstein
Alzheimers For Dummies by Patricia B Smith
Some famous person died of Alzheimers
Fantasy author Sir Terry Pratchett dies at 66
Sir Terry Pratchett renowned fantasy author of more than 70 books has died at age 66
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Alcohol ndash Drinking above recommended levels of alcohol significantly increases the risk of developing dementias such as Alzheimers and vascular dementia However research suggests that light-to-moderate amounts of alcohol may protect the brain against dementia and keep the heart and vascular system healthy
Social activity ndash Research suggests that people who are more socially active have a slightly reduced risk of developing dementia
Mental activity ndash Research suggests that people who take part in mental activities (such as reading learning and doing puzzles) are less likely to develop dementia compared with those who do not engage in these activities
Continuedhelliphelliphelliphelliphelliphellip
Diagnosing for AD
Diagnosing AD
Experienced physicians in specialized AD centers can now diagnose AD with up to 90 percent accuracy Early diagnosis has advantages
bull Doctors can rule out other conditions that may cause dementia
bull If it is AD families have more time to plan for the future
bull Treatments can start earlier when they may be more effective
bull It helps scientists learn more about the causes and development of AD
Slide 29
Physicians today use a number of tools to diagnose AD
bull a detailed patient history
bull information from family and friends
bull physical and neurological exams and lab tests
bull neuropsychological tests
bull imaging tools such as CT scan or magnetic resonance imaging (MRI) PET scans are used primarily for research purposes
CONTINUEDhelliphelliphelliphelliphelliphellip
Slide 30
Clinical trials are the primary way that researchers find out if a promising treatment is safe and effective
bull Trials examine approved drugs to see if they can be used for other purposes or look at experimental drugs
bull Participating in a trial means regular contact with the study team who can provide state-of-the-art AD care
Clinical Trials
Slide 31
Drugs used to treat mild to moderate AD symptoms include
bull Aricept
bull Exelon
bull Reminyl
An additional drug Namenda has been approved to treat symptoms of moderate to severe AD These drugs can help improve some patientsrsquo abilities to carry out activities up to a year or so but they do not stop or reverse AD
Scientists are also studying agents that someday may be useful in preventing AD For example they have experimented with a vaccine against AD Although the first clinical trial was stopped due to side effects in some participants valuable information was gathered
Treatments for AD
Slide 32
Researchers also are looking at other treatments including
bull cholesterol-lowering drugs called statins
bull anti-oxidants (vitamins) and folic acid
bull anti-inflammatory drugs
bull substances that prevent formation of beta-amyloid plaques
bull nerve growth factor to keep neurons healthy
Search for New Treatments
Slide 33
Who are the AD Caregiversbull Spouses ndash the largest group Most are older with
their own health problemsbull Daughters ndash the second largest group Called the
ldquosandwich generationrdquo many are married and raising children of their own Children may need extra support if a parentrsquos attention is focused on care giving
bull Grandchildren ndash may become major helpers
bull Daughters-in-law ndash the third largest group bull Sons ndash often focus on the financial legal and
business aspects of care giving bull Brothers and Sisters ndash many are older with
their own health problemsbull Other ndash friends neighbors members of the
faith community
Support for Caregivers
Slide 37
The NIA is studying how computers can provide information and support to family caregivers through
These features have become very popular among users because they reach many people at once are private and convenient and are available around the clock
bull computer-based bulletin boardsbull chat roomsbull Q amp A modulesbull medical advice forums
Slide 39
Technology and Care giving
One of the great mysteries of Alzheimerrsquos disease is why it largely strikes older adults
Research on how the brain changes normally with age is shedding light on this question For example scientists are learning how age-related changes in the brain may harm neurons and contribute to Alzheimerrsquos damage These age-related changes include atrophy (shrinking) of certain parts of the brain inflammation the production of unstable molecules called free radicals and mitochondrial dysfunction (a breakdown of energy production within a cell)
bull Generally it is diagnosed in people over 65 years of age although the less-prevalent early onset of Alzheimerrsquos can occur much earlier
bull In 2006 there were 266 million sufferers worldwide
bull Alzheimerrsquos is predicted to affect 1 in 85 people globally by 2050
Signs Of Normal Change vs Early Alzheimerrsquos Symptoms
Normal Early Alzheimerrsquos Disease
Canrsquot find your keys Routinely place important items in odd places such as keys in the fridge wallet in the dishwasher
Search for casual names and words
Forget names of family members and common objects or substitute words with inappropriate ones
Briefly forget conversation details
Frequently forget entire conversations
Feel the cold more Dress regardless of the weather wear several skirts on a warm day or shorts in a snow storm
Canrsquot find a recipe Canrsquot follow recipe directions
Forget to record a check Can no longer manage checkbook balance figures solve problems or think abstractly
Cancel a date with friends Withdraw from usual interests and activities sit in front of the TV for hours sleep far more than usual
Make an occasional wrong turn
Get lost in familiar places donrsquot remember how you got there or how to get home
Feel occasionally sad Experience rapid mood swings from tears to rage for no discernible reason
Life expectancyOn average people with Alzheimers disease live for around 8 to 10 years after they start to develop symptoms However this can vary considerably from person to person Some people with the condition will live longer than this but others will not
Alzheimers disease is not usually the actual cause of death but it is often a contributing factor For example a leading cause of death in people with Alzheimers disease is pneumonia (lung infection) which may go untreated because people with the condition often arent able to recognize that theyre ill or may not be able to tell someone they are feeling unwell
RESULTS 1203 subjects were resurveyed in 1997 and among them 124 new cases of dementia including 81 cases of AD were identified By computing the relative risk(RR) of psychosocial factors to the AD many psychosocial factors were found to be correlated with AD including blue collar occupation no job no reading or writing no taking community activities no gardening in leisure bad psychological feeling and lower education (RR gt 1) The items with high PARP gt 50 were not working no job retirement no taking community activities no reading or writing blue collar occupation and no gardening in leisure MMSE total score is a good predict for AD
Psychosocial risk factors of Alzheimers disease
Too much cake and chocolate could cause Alzheimers disease new research claims
Risk The study adds further evidence to links between diabetes and dementia
Eating too many chocolates cakes and other sugary treats could help trigger Alzheimerrsquos disease says new research
bullA study in mice found high levels of blood sugar rapidly increased rogue proteins in the body which combine and kill brain cells ultimately leading to dementia
CONTINUEDhelliphelliphelliphelliphellip
Green tea has also been proven to have beneficial effects when it comes to
Alzheimers(ALAMY)
Some famous books on Alzheimers
The 36-Hour Day fifth edition The 36-Hour by Nancy L Mace
Learning to Speak Alzheimers A Groundbrea
by Joanne Koenig Coste
The Validation Breakthrough Third Edition by Naomi Feil MSW
Alzheimers Disease What If There Was a Cu by Mary T Newport
A Caregivers Guide to Alzheimers Disease by Patricia R Callone
Creating Moments of Joy for the Person with by Jolene Brackey
Alzheimers Early Stages First Steps for F by Daniel Kuhn
Alzheimers Disease and Other Dementias - T by Nataly Rubinstein
Alzheimers For Dummies by Patricia B Smith
Some famous person died of Alzheimers
Fantasy author Sir Terry Pratchett dies at 66
Sir Terry Pratchett renowned fantasy author of more than 70 books has died at age 66
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Diagnosing for AD
Diagnosing AD
Experienced physicians in specialized AD centers can now diagnose AD with up to 90 percent accuracy Early diagnosis has advantages
bull Doctors can rule out other conditions that may cause dementia
bull If it is AD families have more time to plan for the future
bull Treatments can start earlier when they may be more effective
bull It helps scientists learn more about the causes and development of AD
Slide 29
Physicians today use a number of tools to diagnose AD
bull a detailed patient history
bull information from family and friends
bull physical and neurological exams and lab tests
bull neuropsychological tests
bull imaging tools such as CT scan or magnetic resonance imaging (MRI) PET scans are used primarily for research purposes
CONTINUEDhelliphelliphelliphelliphelliphellip
Slide 30
Clinical trials are the primary way that researchers find out if a promising treatment is safe and effective
bull Trials examine approved drugs to see if they can be used for other purposes or look at experimental drugs
bull Participating in a trial means regular contact with the study team who can provide state-of-the-art AD care
Clinical Trials
Slide 31
Drugs used to treat mild to moderate AD symptoms include
bull Aricept
bull Exelon
bull Reminyl
An additional drug Namenda has been approved to treat symptoms of moderate to severe AD These drugs can help improve some patientsrsquo abilities to carry out activities up to a year or so but they do not stop or reverse AD
Scientists are also studying agents that someday may be useful in preventing AD For example they have experimented with a vaccine against AD Although the first clinical trial was stopped due to side effects in some participants valuable information was gathered
Treatments for AD
Slide 32
Researchers also are looking at other treatments including
bull cholesterol-lowering drugs called statins
bull anti-oxidants (vitamins) and folic acid
bull anti-inflammatory drugs
bull substances that prevent formation of beta-amyloid plaques
bull nerve growth factor to keep neurons healthy
Search for New Treatments
Slide 33
Who are the AD Caregiversbull Spouses ndash the largest group Most are older with
their own health problemsbull Daughters ndash the second largest group Called the
ldquosandwich generationrdquo many are married and raising children of their own Children may need extra support if a parentrsquos attention is focused on care giving
bull Grandchildren ndash may become major helpers
bull Daughters-in-law ndash the third largest group bull Sons ndash often focus on the financial legal and
business aspects of care giving bull Brothers and Sisters ndash many are older with
their own health problemsbull Other ndash friends neighbors members of the
faith community
Support for Caregivers
Slide 37
The NIA is studying how computers can provide information and support to family caregivers through
These features have become very popular among users because they reach many people at once are private and convenient and are available around the clock
bull computer-based bulletin boardsbull chat roomsbull Q amp A modulesbull medical advice forums
Slide 39
Technology and Care giving
One of the great mysteries of Alzheimerrsquos disease is why it largely strikes older adults
Research on how the brain changes normally with age is shedding light on this question For example scientists are learning how age-related changes in the brain may harm neurons and contribute to Alzheimerrsquos damage These age-related changes include atrophy (shrinking) of certain parts of the brain inflammation the production of unstable molecules called free radicals and mitochondrial dysfunction (a breakdown of energy production within a cell)
bull Generally it is diagnosed in people over 65 years of age although the less-prevalent early onset of Alzheimerrsquos can occur much earlier
bull In 2006 there were 266 million sufferers worldwide
bull Alzheimerrsquos is predicted to affect 1 in 85 people globally by 2050
Signs Of Normal Change vs Early Alzheimerrsquos Symptoms
Normal Early Alzheimerrsquos Disease
Canrsquot find your keys Routinely place important items in odd places such as keys in the fridge wallet in the dishwasher
Search for casual names and words
Forget names of family members and common objects or substitute words with inappropriate ones
Briefly forget conversation details
Frequently forget entire conversations
Feel the cold more Dress regardless of the weather wear several skirts on a warm day or shorts in a snow storm
Canrsquot find a recipe Canrsquot follow recipe directions
Forget to record a check Can no longer manage checkbook balance figures solve problems or think abstractly
Cancel a date with friends Withdraw from usual interests and activities sit in front of the TV for hours sleep far more than usual
Make an occasional wrong turn
Get lost in familiar places donrsquot remember how you got there or how to get home
Feel occasionally sad Experience rapid mood swings from tears to rage for no discernible reason
Life expectancyOn average people with Alzheimers disease live for around 8 to 10 years after they start to develop symptoms However this can vary considerably from person to person Some people with the condition will live longer than this but others will not
Alzheimers disease is not usually the actual cause of death but it is often a contributing factor For example a leading cause of death in people with Alzheimers disease is pneumonia (lung infection) which may go untreated because people with the condition often arent able to recognize that theyre ill or may not be able to tell someone they are feeling unwell
RESULTS 1203 subjects were resurveyed in 1997 and among them 124 new cases of dementia including 81 cases of AD were identified By computing the relative risk(RR) of psychosocial factors to the AD many psychosocial factors were found to be correlated with AD including blue collar occupation no job no reading or writing no taking community activities no gardening in leisure bad psychological feeling and lower education (RR gt 1) The items with high PARP gt 50 were not working no job retirement no taking community activities no reading or writing blue collar occupation and no gardening in leisure MMSE total score is a good predict for AD
Psychosocial risk factors of Alzheimers disease
Too much cake and chocolate could cause Alzheimers disease new research claims
Risk The study adds further evidence to links between diabetes and dementia
Eating too many chocolates cakes and other sugary treats could help trigger Alzheimerrsquos disease says new research
bullA study in mice found high levels of blood sugar rapidly increased rogue proteins in the body which combine and kill brain cells ultimately leading to dementia
CONTINUEDhelliphelliphelliphelliphellip
Green tea has also been proven to have beneficial effects when it comes to
Alzheimers(ALAMY)
Some famous books on Alzheimers
The 36-Hour Day fifth edition The 36-Hour by Nancy L Mace
Learning to Speak Alzheimers A Groundbrea
by Joanne Koenig Coste
The Validation Breakthrough Third Edition by Naomi Feil MSW
Alzheimers Disease What If There Was a Cu by Mary T Newport
A Caregivers Guide to Alzheimers Disease by Patricia R Callone
Creating Moments of Joy for the Person with by Jolene Brackey
Alzheimers Early Stages First Steps for F by Daniel Kuhn
Alzheimers Disease and Other Dementias - T by Nataly Rubinstein
Alzheimers For Dummies by Patricia B Smith
Some famous person died of Alzheimers
Fantasy author Sir Terry Pratchett dies at 66
Sir Terry Pratchett renowned fantasy author of more than 70 books has died at age 66
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Diagnosing AD
Experienced physicians in specialized AD centers can now diagnose AD with up to 90 percent accuracy Early diagnosis has advantages
bull Doctors can rule out other conditions that may cause dementia
bull If it is AD families have more time to plan for the future
bull Treatments can start earlier when they may be more effective
bull It helps scientists learn more about the causes and development of AD
Slide 29
Physicians today use a number of tools to diagnose AD
bull a detailed patient history
bull information from family and friends
bull physical and neurological exams and lab tests
bull neuropsychological tests
bull imaging tools such as CT scan or magnetic resonance imaging (MRI) PET scans are used primarily for research purposes
CONTINUEDhelliphelliphelliphelliphelliphellip
Slide 30
Clinical trials are the primary way that researchers find out if a promising treatment is safe and effective
bull Trials examine approved drugs to see if they can be used for other purposes or look at experimental drugs
bull Participating in a trial means regular contact with the study team who can provide state-of-the-art AD care
Clinical Trials
Slide 31
Drugs used to treat mild to moderate AD symptoms include
bull Aricept
bull Exelon
bull Reminyl
An additional drug Namenda has been approved to treat symptoms of moderate to severe AD These drugs can help improve some patientsrsquo abilities to carry out activities up to a year or so but they do not stop or reverse AD
Scientists are also studying agents that someday may be useful in preventing AD For example they have experimented with a vaccine against AD Although the first clinical trial was stopped due to side effects in some participants valuable information was gathered
Treatments for AD
Slide 32
Researchers also are looking at other treatments including
bull cholesterol-lowering drugs called statins
bull anti-oxidants (vitamins) and folic acid
bull anti-inflammatory drugs
bull substances that prevent formation of beta-amyloid plaques
bull nerve growth factor to keep neurons healthy
Search for New Treatments
Slide 33
Who are the AD Caregiversbull Spouses ndash the largest group Most are older with
their own health problemsbull Daughters ndash the second largest group Called the
ldquosandwich generationrdquo many are married and raising children of their own Children may need extra support if a parentrsquos attention is focused on care giving
bull Grandchildren ndash may become major helpers
bull Daughters-in-law ndash the third largest group bull Sons ndash often focus on the financial legal and
business aspects of care giving bull Brothers and Sisters ndash many are older with
their own health problemsbull Other ndash friends neighbors members of the
faith community
Support for Caregivers
Slide 37
The NIA is studying how computers can provide information and support to family caregivers through
These features have become very popular among users because they reach many people at once are private and convenient and are available around the clock
bull computer-based bulletin boardsbull chat roomsbull Q amp A modulesbull medical advice forums
Slide 39
Technology and Care giving
One of the great mysteries of Alzheimerrsquos disease is why it largely strikes older adults
Research on how the brain changes normally with age is shedding light on this question For example scientists are learning how age-related changes in the brain may harm neurons and contribute to Alzheimerrsquos damage These age-related changes include atrophy (shrinking) of certain parts of the brain inflammation the production of unstable molecules called free radicals and mitochondrial dysfunction (a breakdown of energy production within a cell)
bull Generally it is diagnosed in people over 65 years of age although the less-prevalent early onset of Alzheimerrsquos can occur much earlier
bull In 2006 there were 266 million sufferers worldwide
bull Alzheimerrsquos is predicted to affect 1 in 85 people globally by 2050
Signs Of Normal Change vs Early Alzheimerrsquos Symptoms
Normal Early Alzheimerrsquos Disease
Canrsquot find your keys Routinely place important items in odd places such as keys in the fridge wallet in the dishwasher
Search for casual names and words
Forget names of family members and common objects or substitute words with inappropriate ones
Briefly forget conversation details
Frequently forget entire conversations
Feel the cold more Dress regardless of the weather wear several skirts on a warm day or shorts in a snow storm
Canrsquot find a recipe Canrsquot follow recipe directions
Forget to record a check Can no longer manage checkbook balance figures solve problems or think abstractly
Cancel a date with friends Withdraw from usual interests and activities sit in front of the TV for hours sleep far more than usual
Make an occasional wrong turn
Get lost in familiar places donrsquot remember how you got there or how to get home
Feel occasionally sad Experience rapid mood swings from tears to rage for no discernible reason
Life expectancyOn average people with Alzheimers disease live for around 8 to 10 years after they start to develop symptoms However this can vary considerably from person to person Some people with the condition will live longer than this but others will not
Alzheimers disease is not usually the actual cause of death but it is often a contributing factor For example a leading cause of death in people with Alzheimers disease is pneumonia (lung infection) which may go untreated because people with the condition often arent able to recognize that theyre ill or may not be able to tell someone they are feeling unwell
RESULTS 1203 subjects were resurveyed in 1997 and among them 124 new cases of dementia including 81 cases of AD were identified By computing the relative risk(RR) of psychosocial factors to the AD many psychosocial factors were found to be correlated with AD including blue collar occupation no job no reading or writing no taking community activities no gardening in leisure bad psychological feeling and lower education (RR gt 1) The items with high PARP gt 50 were not working no job retirement no taking community activities no reading or writing blue collar occupation and no gardening in leisure MMSE total score is a good predict for AD
Psychosocial risk factors of Alzheimers disease
Too much cake and chocolate could cause Alzheimers disease new research claims
Risk The study adds further evidence to links between diabetes and dementia
Eating too many chocolates cakes and other sugary treats could help trigger Alzheimerrsquos disease says new research
bullA study in mice found high levels of blood sugar rapidly increased rogue proteins in the body which combine and kill brain cells ultimately leading to dementia
CONTINUEDhelliphelliphelliphelliphellip
Green tea has also been proven to have beneficial effects when it comes to
Alzheimers(ALAMY)
Some famous books on Alzheimers
The 36-Hour Day fifth edition The 36-Hour by Nancy L Mace
Learning to Speak Alzheimers A Groundbrea
by Joanne Koenig Coste
The Validation Breakthrough Third Edition by Naomi Feil MSW
Alzheimers Disease What If There Was a Cu by Mary T Newport
A Caregivers Guide to Alzheimers Disease by Patricia R Callone
Creating Moments of Joy for the Person with by Jolene Brackey
Alzheimers Early Stages First Steps for F by Daniel Kuhn
Alzheimers Disease and Other Dementias - T by Nataly Rubinstein
Alzheimers For Dummies by Patricia B Smith
Some famous person died of Alzheimers
Fantasy author Sir Terry Pratchett dies at 66
Sir Terry Pratchett renowned fantasy author of more than 70 books has died at age 66
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Physicians today use a number of tools to diagnose AD
bull a detailed patient history
bull information from family and friends
bull physical and neurological exams and lab tests
bull neuropsychological tests
bull imaging tools such as CT scan or magnetic resonance imaging (MRI) PET scans are used primarily for research purposes
CONTINUEDhelliphelliphelliphelliphelliphellip
Slide 30
Clinical trials are the primary way that researchers find out if a promising treatment is safe and effective
bull Trials examine approved drugs to see if they can be used for other purposes or look at experimental drugs
bull Participating in a trial means regular contact with the study team who can provide state-of-the-art AD care
Clinical Trials
Slide 31
Drugs used to treat mild to moderate AD symptoms include
bull Aricept
bull Exelon
bull Reminyl
An additional drug Namenda has been approved to treat symptoms of moderate to severe AD These drugs can help improve some patientsrsquo abilities to carry out activities up to a year or so but they do not stop or reverse AD
Scientists are also studying agents that someday may be useful in preventing AD For example they have experimented with a vaccine against AD Although the first clinical trial was stopped due to side effects in some participants valuable information was gathered
Treatments for AD
Slide 32
Researchers also are looking at other treatments including
bull cholesterol-lowering drugs called statins
bull anti-oxidants (vitamins) and folic acid
bull anti-inflammatory drugs
bull substances that prevent formation of beta-amyloid plaques
bull nerve growth factor to keep neurons healthy
Search for New Treatments
Slide 33
Who are the AD Caregiversbull Spouses ndash the largest group Most are older with
their own health problemsbull Daughters ndash the second largest group Called the
ldquosandwich generationrdquo many are married and raising children of their own Children may need extra support if a parentrsquos attention is focused on care giving
bull Grandchildren ndash may become major helpers
bull Daughters-in-law ndash the third largest group bull Sons ndash often focus on the financial legal and
business aspects of care giving bull Brothers and Sisters ndash many are older with
their own health problemsbull Other ndash friends neighbors members of the
faith community
Support for Caregivers
Slide 37
The NIA is studying how computers can provide information and support to family caregivers through
These features have become very popular among users because they reach many people at once are private and convenient and are available around the clock
bull computer-based bulletin boardsbull chat roomsbull Q amp A modulesbull medical advice forums
Slide 39
Technology and Care giving
One of the great mysteries of Alzheimerrsquos disease is why it largely strikes older adults
Research on how the brain changes normally with age is shedding light on this question For example scientists are learning how age-related changes in the brain may harm neurons and contribute to Alzheimerrsquos damage These age-related changes include atrophy (shrinking) of certain parts of the brain inflammation the production of unstable molecules called free radicals and mitochondrial dysfunction (a breakdown of energy production within a cell)
bull Generally it is diagnosed in people over 65 years of age although the less-prevalent early onset of Alzheimerrsquos can occur much earlier
bull In 2006 there were 266 million sufferers worldwide
bull Alzheimerrsquos is predicted to affect 1 in 85 people globally by 2050
Signs Of Normal Change vs Early Alzheimerrsquos Symptoms
Normal Early Alzheimerrsquos Disease
Canrsquot find your keys Routinely place important items in odd places such as keys in the fridge wallet in the dishwasher
Search for casual names and words
Forget names of family members and common objects or substitute words with inappropriate ones
Briefly forget conversation details
Frequently forget entire conversations
Feel the cold more Dress regardless of the weather wear several skirts on a warm day or shorts in a snow storm
Canrsquot find a recipe Canrsquot follow recipe directions
Forget to record a check Can no longer manage checkbook balance figures solve problems or think abstractly
Cancel a date with friends Withdraw from usual interests and activities sit in front of the TV for hours sleep far more than usual
Make an occasional wrong turn
Get lost in familiar places donrsquot remember how you got there or how to get home
Feel occasionally sad Experience rapid mood swings from tears to rage for no discernible reason
Life expectancyOn average people with Alzheimers disease live for around 8 to 10 years after they start to develop symptoms However this can vary considerably from person to person Some people with the condition will live longer than this but others will not
Alzheimers disease is not usually the actual cause of death but it is often a contributing factor For example a leading cause of death in people with Alzheimers disease is pneumonia (lung infection) which may go untreated because people with the condition often arent able to recognize that theyre ill or may not be able to tell someone they are feeling unwell
RESULTS 1203 subjects were resurveyed in 1997 and among them 124 new cases of dementia including 81 cases of AD were identified By computing the relative risk(RR) of psychosocial factors to the AD many psychosocial factors were found to be correlated with AD including blue collar occupation no job no reading or writing no taking community activities no gardening in leisure bad psychological feeling and lower education (RR gt 1) The items with high PARP gt 50 were not working no job retirement no taking community activities no reading or writing blue collar occupation and no gardening in leisure MMSE total score is a good predict for AD
Psychosocial risk factors of Alzheimers disease
Too much cake and chocolate could cause Alzheimers disease new research claims
Risk The study adds further evidence to links between diabetes and dementia
Eating too many chocolates cakes and other sugary treats could help trigger Alzheimerrsquos disease says new research
bullA study in mice found high levels of blood sugar rapidly increased rogue proteins in the body which combine and kill brain cells ultimately leading to dementia
CONTINUEDhelliphelliphelliphelliphellip
Green tea has also been proven to have beneficial effects when it comes to
Alzheimers(ALAMY)
Some famous books on Alzheimers
The 36-Hour Day fifth edition The 36-Hour by Nancy L Mace
Learning to Speak Alzheimers A Groundbrea
by Joanne Koenig Coste
The Validation Breakthrough Third Edition by Naomi Feil MSW
Alzheimers Disease What If There Was a Cu by Mary T Newport
A Caregivers Guide to Alzheimers Disease by Patricia R Callone
Creating Moments of Joy for the Person with by Jolene Brackey
Alzheimers Early Stages First Steps for F by Daniel Kuhn
Alzheimers Disease and Other Dementias - T by Nataly Rubinstein
Alzheimers For Dummies by Patricia B Smith
Some famous person died of Alzheimers
Fantasy author Sir Terry Pratchett dies at 66
Sir Terry Pratchett renowned fantasy author of more than 70 books has died at age 66
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Clinical trials are the primary way that researchers find out if a promising treatment is safe and effective
bull Trials examine approved drugs to see if they can be used for other purposes or look at experimental drugs
bull Participating in a trial means regular contact with the study team who can provide state-of-the-art AD care
Clinical Trials
Slide 31
Drugs used to treat mild to moderate AD symptoms include
bull Aricept
bull Exelon
bull Reminyl
An additional drug Namenda has been approved to treat symptoms of moderate to severe AD These drugs can help improve some patientsrsquo abilities to carry out activities up to a year or so but they do not stop or reverse AD
Scientists are also studying agents that someday may be useful in preventing AD For example they have experimented with a vaccine against AD Although the first clinical trial was stopped due to side effects in some participants valuable information was gathered
Treatments for AD
Slide 32
Researchers also are looking at other treatments including
bull cholesterol-lowering drugs called statins
bull anti-oxidants (vitamins) and folic acid
bull anti-inflammatory drugs
bull substances that prevent formation of beta-amyloid plaques
bull nerve growth factor to keep neurons healthy
Search for New Treatments
Slide 33
Who are the AD Caregiversbull Spouses ndash the largest group Most are older with
their own health problemsbull Daughters ndash the second largest group Called the
ldquosandwich generationrdquo many are married and raising children of their own Children may need extra support if a parentrsquos attention is focused on care giving
bull Grandchildren ndash may become major helpers
bull Daughters-in-law ndash the third largest group bull Sons ndash often focus on the financial legal and
business aspects of care giving bull Brothers and Sisters ndash many are older with
their own health problemsbull Other ndash friends neighbors members of the
faith community
Support for Caregivers
Slide 37
The NIA is studying how computers can provide information and support to family caregivers through
These features have become very popular among users because they reach many people at once are private and convenient and are available around the clock
bull computer-based bulletin boardsbull chat roomsbull Q amp A modulesbull medical advice forums
Slide 39
Technology and Care giving
One of the great mysteries of Alzheimerrsquos disease is why it largely strikes older adults
Research on how the brain changes normally with age is shedding light on this question For example scientists are learning how age-related changes in the brain may harm neurons and contribute to Alzheimerrsquos damage These age-related changes include atrophy (shrinking) of certain parts of the brain inflammation the production of unstable molecules called free radicals and mitochondrial dysfunction (a breakdown of energy production within a cell)
bull Generally it is diagnosed in people over 65 years of age although the less-prevalent early onset of Alzheimerrsquos can occur much earlier
bull In 2006 there were 266 million sufferers worldwide
bull Alzheimerrsquos is predicted to affect 1 in 85 people globally by 2050
Signs Of Normal Change vs Early Alzheimerrsquos Symptoms
Normal Early Alzheimerrsquos Disease
Canrsquot find your keys Routinely place important items in odd places such as keys in the fridge wallet in the dishwasher
Search for casual names and words
Forget names of family members and common objects or substitute words with inappropriate ones
Briefly forget conversation details
Frequently forget entire conversations
Feel the cold more Dress regardless of the weather wear several skirts on a warm day or shorts in a snow storm
Canrsquot find a recipe Canrsquot follow recipe directions
Forget to record a check Can no longer manage checkbook balance figures solve problems or think abstractly
Cancel a date with friends Withdraw from usual interests and activities sit in front of the TV for hours sleep far more than usual
Make an occasional wrong turn
Get lost in familiar places donrsquot remember how you got there or how to get home
Feel occasionally sad Experience rapid mood swings from tears to rage for no discernible reason
Life expectancyOn average people with Alzheimers disease live for around 8 to 10 years after they start to develop symptoms However this can vary considerably from person to person Some people with the condition will live longer than this but others will not
Alzheimers disease is not usually the actual cause of death but it is often a contributing factor For example a leading cause of death in people with Alzheimers disease is pneumonia (lung infection) which may go untreated because people with the condition often arent able to recognize that theyre ill or may not be able to tell someone they are feeling unwell
RESULTS 1203 subjects were resurveyed in 1997 and among them 124 new cases of dementia including 81 cases of AD were identified By computing the relative risk(RR) of psychosocial factors to the AD many psychosocial factors were found to be correlated with AD including blue collar occupation no job no reading or writing no taking community activities no gardening in leisure bad psychological feeling and lower education (RR gt 1) The items with high PARP gt 50 were not working no job retirement no taking community activities no reading or writing blue collar occupation and no gardening in leisure MMSE total score is a good predict for AD
Psychosocial risk factors of Alzheimers disease
Too much cake and chocolate could cause Alzheimers disease new research claims
Risk The study adds further evidence to links between diabetes and dementia
Eating too many chocolates cakes and other sugary treats could help trigger Alzheimerrsquos disease says new research
bullA study in mice found high levels of blood sugar rapidly increased rogue proteins in the body which combine and kill brain cells ultimately leading to dementia
CONTINUEDhelliphelliphelliphelliphellip
Green tea has also been proven to have beneficial effects when it comes to
Alzheimers(ALAMY)
Some famous books on Alzheimers
The 36-Hour Day fifth edition The 36-Hour by Nancy L Mace
Learning to Speak Alzheimers A Groundbrea
by Joanne Koenig Coste
The Validation Breakthrough Third Edition by Naomi Feil MSW
Alzheimers Disease What If There Was a Cu by Mary T Newport
A Caregivers Guide to Alzheimers Disease by Patricia R Callone
Creating Moments of Joy for the Person with by Jolene Brackey
Alzheimers Early Stages First Steps for F by Daniel Kuhn
Alzheimers Disease and Other Dementias - T by Nataly Rubinstein
Alzheimers For Dummies by Patricia B Smith
Some famous person died of Alzheimers
Fantasy author Sir Terry Pratchett dies at 66
Sir Terry Pratchett renowned fantasy author of more than 70 books has died at age 66
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Drugs used to treat mild to moderate AD symptoms include
bull Aricept
bull Exelon
bull Reminyl
An additional drug Namenda has been approved to treat symptoms of moderate to severe AD These drugs can help improve some patientsrsquo abilities to carry out activities up to a year or so but they do not stop or reverse AD
Scientists are also studying agents that someday may be useful in preventing AD For example they have experimented with a vaccine against AD Although the first clinical trial was stopped due to side effects in some participants valuable information was gathered
Treatments for AD
Slide 32
Researchers also are looking at other treatments including
bull cholesterol-lowering drugs called statins
bull anti-oxidants (vitamins) and folic acid
bull anti-inflammatory drugs
bull substances that prevent formation of beta-amyloid plaques
bull nerve growth factor to keep neurons healthy
Search for New Treatments
Slide 33
Who are the AD Caregiversbull Spouses ndash the largest group Most are older with
their own health problemsbull Daughters ndash the second largest group Called the
ldquosandwich generationrdquo many are married and raising children of their own Children may need extra support if a parentrsquos attention is focused on care giving
bull Grandchildren ndash may become major helpers
bull Daughters-in-law ndash the third largest group bull Sons ndash often focus on the financial legal and
business aspects of care giving bull Brothers and Sisters ndash many are older with
their own health problemsbull Other ndash friends neighbors members of the
faith community
Support for Caregivers
Slide 37
The NIA is studying how computers can provide information and support to family caregivers through
These features have become very popular among users because they reach many people at once are private and convenient and are available around the clock
bull computer-based bulletin boardsbull chat roomsbull Q amp A modulesbull medical advice forums
Slide 39
Technology and Care giving
One of the great mysteries of Alzheimerrsquos disease is why it largely strikes older adults
Research on how the brain changes normally with age is shedding light on this question For example scientists are learning how age-related changes in the brain may harm neurons and contribute to Alzheimerrsquos damage These age-related changes include atrophy (shrinking) of certain parts of the brain inflammation the production of unstable molecules called free radicals and mitochondrial dysfunction (a breakdown of energy production within a cell)
bull Generally it is diagnosed in people over 65 years of age although the less-prevalent early onset of Alzheimerrsquos can occur much earlier
bull In 2006 there were 266 million sufferers worldwide
bull Alzheimerrsquos is predicted to affect 1 in 85 people globally by 2050
Signs Of Normal Change vs Early Alzheimerrsquos Symptoms
Normal Early Alzheimerrsquos Disease
Canrsquot find your keys Routinely place important items in odd places such as keys in the fridge wallet in the dishwasher
Search for casual names and words
Forget names of family members and common objects or substitute words with inappropriate ones
Briefly forget conversation details
Frequently forget entire conversations
Feel the cold more Dress regardless of the weather wear several skirts on a warm day or shorts in a snow storm
Canrsquot find a recipe Canrsquot follow recipe directions
Forget to record a check Can no longer manage checkbook balance figures solve problems or think abstractly
Cancel a date with friends Withdraw from usual interests and activities sit in front of the TV for hours sleep far more than usual
Make an occasional wrong turn
Get lost in familiar places donrsquot remember how you got there or how to get home
Feel occasionally sad Experience rapid mood swings from tears to rage for no discernible reason
Life expectancyOn average people with Alzheimers disease live for around 8 to 10 years after they start to develop symptoms However this can vary considerably from person to person Some people with the condition will live longer than this but others will not
Alzheimers disease is not usually the actual cause of death but it is often a contributing factor For example a leading cause of death in people with Alzheimers disease is pneumonia (lung infection) which may go untreated because people with the condition often arent able to recognize that theyre ill or may not be able to tell someone they are feeling unwell
RESULTS 1203 subjects were resurveyed in 1997 and among them 124 new cases of dementia including 81 cases of AD were identified By computing the relative risk(RR) of psychosocial factors to the AD many psychosocial factors were found to be correlated with AD including blue collar occupation no job no reading or writing no taking community activities no gardening in leisure bad psychological feeling and lower education (RR gt 1) The items with high PARP gt 50 were not working no job retirement no taking community activities no reading or writing blue collar occupation and no gardening in leisure MMSE total score is a good predict for AD
Psychosocial risk factors of Alzheimers disease
Too much cake and chocolate could cause Alzheimers disease new research claims
Risk The study adds further evidence to links between diabetes and dementia
Eating too many chocolates cakes and other sugary treats could help trigger Alzheimerrsquos disease says new research
bullA study in mice found high levels of blood sugar rapidly increased rogue proteins in the body which combine and kill brain cells ultimately leading to dementia
CONTINUEDhelliphelliphelliphelliphellip
Green tea has also been proven to have beneficial effects when it comes to
Alzheimers(ALAMY)
Some famous books on Alzheimers
The 36-Hour Day fifth edition The 36-Hour by Nancy L Mace
Learning to Speak Alzheimers A Groundbrea
by Joanne Koenig Coste
The Validation Breakthrough Third Edition by Naomi Feil MSW
Alzheimers Disease What If There Was a Cu by Mary T Newport
A Caregivers Guide to Alzheimers Disease by Patricia R Callone
Creating Moments of Joy for the Person with by Jolene Brackey
Alzheimers Early Stages First Steps for F by Daniel Kuhn
Alzheimers Disease and Other Dementias - T by Nataly Rubinstein
Alzheimers For Dummies by Patricia B Smith
Some famous person died of Alzheimers
Fantasy author Sir Terry Pratchett dies at 66
Sir Terry Pratchett renowned fantasy author of more than 70 books has died at age 66
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Researchers also are looking at other treatments including
bull cholesterol-lowering drugs called statins
bull anti-oxidants (vitamins) and folic acid
bull anti-inflammatory drugs
bull substances that prevent formation of beta-amyloid plaques
bull nerve growth factor to keep neurons healthy
Search for New Treatments
Slide 33
Who are the AD Caregiversbull Spouses ndash the largest group Most are older with
their own health problemsbull Daughters ndash the second largest group Called the
ldquosandwich generationrdquo many are married and raising children of their own Children may need extra support if a parentrsquos attention is focused on care giving
bull Grandchildren ndash may become major helpers
bull Daughters-in-law ndash the third largest group bull Sons ndash often focus on the financial legal and
business aspects of care giving bull Brothers and Sisters ndash many are older with
their own health problemsbull Other ndash friends neighbors members of the
faith community
Support for Caregivers
Slide 37
The NIA is studying how computers can provide information and support to family caregivers through
These features have become very popular among users because they reach many people at once are private and convenient and are available around the clock
bull computer-based bulletin boardsbull chat roomsbull Q amp A modulesbull medical advice forums
Slide 39
Technology and Care giving
One of the great mysteries of Alzheimerrsquos disease is why it largely strikes older adults
Research on how the brain changes normally with age is shedding light on this question For example scientists are learning how age-related changes in the brain may harm neurons and contribute to Alzheimerrsquos damage These age-related changes include atrophy (shrinking) of certain parts of the brain inflammation the production of unstable molecules called free radicals and mitochondrial dysfunction (a breakdown of energy production within a cell)
bull Generally it is diagnosed in people over 65 years of age although the less-prevalent early onset of Alzheimerrsquos can occur much earlier
bull In 2006 there were 266 million sufferers worldwide
bull Alzheimerrsquos is predicted to affect 1 in 85 people globally by 2050
Signs Of Normal Change vs Early Alzheimerrsquos Symptoms
Normal Early Alzheimerrsquos Disease
Canrsquot find your keys Routinely place important items in odd places such as keys in the fridge wallet in the dishwasher
Search for casual names and words
Forget names of family members and common objects or substitute words with inappropriate ones
Briefly forget conversation details
Frequently forget entire conversations
Feel the cold more Dress regardless of the weather wear several skirts on a warm day or shorts in a snow storm
Canrsquot find a recipe Canrsquot follow recipe directions
Forget to record a check Can no longer manage checkbook balance figures solve problems or think abstractly
Cancel a date with friends Withdraw from usual interests and activities sit in front of the TV for hours sleep far more than usual
Make an occasional wrong turn
Get lost in familiar places donrsquot remember how you got there or how to get home
Feel occasionally sad Experience rapid mood swings from tears to rage for no discernible reason
Life expectancyOn average people with Alzheimers disease live for around 8 to 10 years after they start to develop symptoms However this can vary considerably from person to person Some people with the condition will live longer than this but others will not
Alzheimers disease is not usually the actual cause of death but it is often a contributing factor For example a leading cause of death in people with Alzheimers disease is pneumonia (lung infection) which may go untreated because people with the condition often arent able to recognize that theyre ill or may not be able to tell someone they are feeling unwell
RESULTS 1203 subjects were resurveyed in 1997 and among them 124 new cases of dementia including 81 cases of AD were identified By computing the relative risk(RR) of psychosocial factors to the AD many psychosocial factors were found to be correlated with AD including blue collar occupation no job no reading or writing no taking community activities no gardening in leisure bad psychological feeling and lower education (RR gt 1) The items with high PARP gt 50 were not working no job retirement no taking community activities no reading or writing blue collar occupation and no gardening in leisure MMSE total score is a good predict for AD
Psychosocial risk factors of Alzheimers disease
Too much cake and chocolate could cause Alzheimers disease new research claims
Risk The study adds further evidence to links between diabetes and dementia
Eating too many chocolates cakes and other sugary treats could help trigger Alzheimerrsquos disease says new research
bullA study in mice found high levels of blood sugar rapidly increased rogue proteins in the body which combine and kill brain cells ultimately leading to dementia
CONTINUEDhelliphelliphelliphelliphellip
Green tea has also been proven to have beneficial effects when it comes to
Alzheimers(ALAMY)
Some famous books on Alzheimers
The 36-Hour Day fifth edition The 36-Hour by Nancy L Mace
Learning to Speak Alzheimers A Groundbrea
by Joanne Koenig Coste
The Validation Breakthrough Third Edition by Naomi Feil MSW
Alzheimers Disease What If There Was a Cu by Mary T Newport
A Caregivers Guide to Alzheimers Disease by Patricia R Callone
Creating Moments of Joy for the Person with by Jolene Brackey
Alzheimers Early Stages First Steps for F by Daniel Kuhn
Alzheimers Disease and Other Dementias - T by Nataly Rubinstein
Alzheimers For Dummies by Patricia B Smith
Some famous person died of Alzheimers
Fantasy author Sir Terry Pratchett dies at 66
Sir Terry Pratchett renowned fantasy author of more than 70 books has died at age 66
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Who are the AD Caregiversbull Spouses ndash the largest group Most are older with
their own health problemsbull Daughters ndash the second largest group Called the
ldquosandwich generationrdquo many are married and raising children of their own Children may need extra support if a parentrsquos attention is focused on care giving
bull Grandchildren ndash may become major helpers
bull Daughters-in-law ndash the third largest group bull Sons ndash often focus on the financial legal and
business aspects of care giving bull Brothers and Sisters ndash many are older with
their own health problemsbull Other ndash friends neighbors members of the
faith community
Support for Caregivers
Slide 37
The NIA is studying how computers can provide information and support to family caregivers through
These features have become very popular among users because they reach many people at once are private and convenient and are available around the clock
bull computer-based bulletin boardsbull chat roomsbull Q amp A modulesbull medical advice forums
Slide 39
Technology and Care giving
One of the great mysteries of Alzheimerrsquos disease is why it largely strikes older adults
Research on how the brain changes normally with age is shedding light on this question For example scientists are learning how age-related changes in the brain may harm neurons and contribute to Alzheimerrsquos damage These age-related changes include atrophy (shrinking) of certain parts of the brain inflammation the production of unstable molecules called free radicals and mitochondrial dysfunction (a breakdown of energy production within a cell)
bull Generally it is diagnosed in people over 65 years of age although the less-prevalent early onset of Alzheimerrsquos can occur much earlier
bull In 2006 there were 266 million sufferers worldwide
bull Alzheimerrsquos is predicted to affect 1 in 85 people globally by 2050
Signs Of Normal Change vs Early Alzheimerrsquos Symptoms
Normal Early Alzheimerrsquos Disease
Canrsquot find your keys Routinely place important items in odd places such as keys in the fridge wallet in the dishwasher
Search for casual names and words
Forget names of family members and common objects or substitute words with inappropriate ones
Briefly forget conversation details
Frequently forget entire conversations
Feel the cold more Dress regardless of the weather wear several skirts on a warm day or shorts in a snow storm
Canrsquot find a recipe Canrsquot follow recipe directions
Forget to record a check Can no longer manage checkbook balance figures solve problems or think abstractly
Cancel a date with friends Withdraw from usual interests and activities sit in front of the TV for hours sleep far more than usual
Make an occasional wrong turn
Get lost in familiar places donrsquot remember how you got there or how to get home
Feel occasionally sad Experience rapid mood swings from tears to rage for no discernible reason
Life expectancyOn average people with Alzheimers disease live for around 8 to 10 years after they start to develop symptoms However this can vary considerably from person to person Some people with the condition will live longer than this but others will not
Alzheimers disease is not usually the actual cause of death but it is often a contributing factor For example a leading cause of death in people with Alzheimers disease is pneumonia (lung infection) which may go untreated because people with the condition often arent able to recognize that theyre ill or may not be able to tell someone they are feeling unwell
RESULTS 1203 subjects were resurveyed in 1997 and among them 124 new cases of dementia including 81 cases of AD were identified By computing the relative risk(RR) of psychosocial factors to the AD many psychosocial factors were found to be correlated with AD including blue collar occupation no job no reading or writing no taking community activities no gardening in leisure bad psychological feeling and lower education (RR gt 1) The items with high PARP gt 50 were not working no job retirement no taking community activities no reading or writing blue collar occupation and no gardening in leisure MMSE total score is a good predict for AD
Psychosocial risk factors of Alzheimers disease
Too much cake and chocolate could cause Alzheimers disease new research claims
Risk The study adds further evidence to links between diabetes and dementia
Eating too many chocolates cakes and other sugary treats could help trigger Alzheimerrsquos disease says new research
bullA study in mice found high levels of blood sugar rapidly increased rogue proteins in the body which combine and kill brain cells ultimately leading to dementia
CONTINUEDhelliphelliphelliphelliphellip
Green tea has also been proven to have beneficial effects when it comes to
Alzheimers(ALAMY)
Some famous books on Alzheimers
The 36-Hour Day fifth edition The 36-Hour by Nancy L Mace
Learning to Speak Alzheimers A Groundbrea
by Joanne Koenig Coste
The Validation Breakthrough Third Edition by Naomi Feil MSW
Alzheimers Disease What If There Was a Cu by Mary T Newport
A Caregivers Guide to Alzheimers Disease by Patricia R Callone
Creating Moments of Joy for the Person with by Jolene Brackey
Alzheimers Early Stages First Steps for F by Daniel Kuhn
Alzheimers Disease and Other Dementias - T by Nataly Rubinstein
Alzheimers For Dummies by Patricia B Smith
Some famous person died of Alzheimers
Fantasy author Sir Terry Pratchett dies at 66
Sir Terry Pratchett renowned fantasy author of more than 70 books has died at age 66
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
The NIA is studying how computers can provide information and support to family caregivers through
These features have become very popular among users because they reach many people at once are private and convenient and are available around the clock
bull computer-based bulletin boardsbull chat roomsbull Q amp A modulesbull medical advice forums
Slide 39
Technology and Care giving
One of the great mysteries of Alzheimerrsquos disease is why it largely strikes older adults
Research on how the brain changes normally with age is shedding light on this question For example scientists are learning how age-related changes in the brain may harm neurons and contribute to Alzheimerrsquos damage These age-related changes include atrophy (shrinking) of certain parts of the brain inflammation the production of unstable molecules called free radicals and mitochondrial dysfunction (a breakdown of energy production within a cell)
bull Generally it is diagnosed in people over 65 years of age although the less-prevalent early onset of Alzheimerrsquos can occur much earlier
bull In 2006 there were 266 million sufferers worldwide
bull Alzheimerrsquos is predicted to affect 1 in 85 people globally by 2050
Signs Of Normal Change vs Early Alzheimerrsquos Symptoms
Normal Early Alzheimerrsquos Disease
Canrsquot find your keys Routinely place important items in odd places such as keys in the fridge wallet in the dishwasher
Search for casual names and words
Forget names of family members and common objects or substitute words with inappropriate ones
Briefly forget conversation details
Frequently forget entire conversations
Feel the cold more Dress regardless of the weather wear several skirts on a warm day or shorts in a snow storm
Canrsquot find a recipe Canrsquot follow recipe directions
Forget to record a check Can no longer manage checkbook balance figures solve problems or think abstractly
Cancel a date with friends Withdraw from usual interests and activities sit in front of the TV for hours sleep far more than usual
Make an occasional wrong turn
Get lost in familiar places donrsquot remember how you got there or how to get home
Feel occasionally sad Experience rapid mood swings from tears to rage for no discernible reason
Life expectancyOn average people with Alzheimers disease live for around 8 to 10 years after they start to develop symptoms However this can vary considerably from person to person Some people with the condition will live longer than this but others will not
Alzheimers disease is not usually the actual cause of death but it is often a contributing factor For example a leading cause of death in people with Alzheimers disease is pneumonia (lung infection) which may go untreated because people with the condition often arent able to recognize that theyre ill or may not be able to tell someone they are feeling unwell
RESULTS 1203 subjects were resurveyed in 1997 and among them 124 new cases of dementia including 81 cases of AD were identified By computing the relative risk(RR) of psychosocial factors to the AD many psychosocial factors were found to be correlated with AD including blue collar occupation no job no reading or writing no taking community activities no gardening in leisure bad psychological feeling and lower education (RR gt 1) The items with high PARP gt 50 were not working no job retirement no taking community activities no reading or writing blue collar occupation and no gardening in leisure MMSE total score is a good predict for AD
Psychosocial risk factors of Alzheimers disease
Too much cake and chocolate could cause Alzheimers disease new research claims
Risk The study adds further evidence to links between diabetes and dementia
Eating too many chocolates cakes and other sugary treats could help trigger Alzheimerrsquos disease says new research
bullA study in mice found high levels of blood sugar rapidly increased rogue proteins in the body which combine and kill brain cells ultimately leading to dementia
CONTINUEDhelliphelliphelliphelliphellip
Green tea has also been proven to have beneficial effects when it comes to
Alzheimers(ALAMY)
Some famous books on Alzheimers
The 36-Hour Day fifth edition The 36-Hour by Nancy L Mace
Learning to Speak Alzheimers A Groundbrea
by Joanne Koenig Coste
The Validation Breakthrough Third Edition by Naomi Feil MSW
Alzheimers Disease What If There Was a Cu by Mary T Newport
A Caregivers Guide to Alzheimers Disease by Patricia R Callone
Creating Moments of Joy for the Person with by Jolene Brackey
Alzheimers Early Stages First Steps for F by Daniel Kuhn
Alzheimers Disease and Other Dementias - T by Nataly Rubinstein
Alzheimers For Dummies by Patricia B Smith
Some famous person died of Alzheimers
Fantasy author Sir Terry Pratchett dies at 66
Sir Terry Pratchett renowned fantasy author of more than 70 books has died at age 66
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
One of the great mysteries of Alzheimerrsquos disease is why it largely strikes older adults
Research on how the brain changes normally with age is shedding light on this question For example scientists are learning how age-related changes in the brain may harm neurons and contribute to Alzheimerrsquos damage These age-related changes include atrophy (shrinking) of certain parts of the brain inflammation the production of unstable molecules called free radicals and mitochondrial dysfunction (a breakdown of energy production within a cell)
bull Generally it is diagnosed in people over 65 years of age although the less-prevalent early onset of Alzheimerrsquos can occur much earlier
bull In 2006 there were 266 million sufferers worldwide
bull Alzheimerrsquos is predicted to affect 1 in 85 people globally by 2050
Signs Of Normal Change vs Early Alzheimerrsquos Symptoms
Normal Early Alzheimerrsquos Disease
Canrsquot find your keys Routinely place important items in odd places such as keys in the fridge wallet in the dishwasher
Search for casual names and words
Forget names of family members and common objects or substitute words with inappropriate ones
Briefly forget conversation details
Frequently forget entire conversations
Feel the cold more Dress regardless of the weather wear several skirts on a warm day or shorts in a snow storm
Canrsquot find a recipe Canrsquot follow recipe directions
Forget to record a check Can no longer manage checkbook balance figures solve problems or think abstractly
Cancel a date with friends Withdraw from usual interests and activities sit in front of the TV for hours sleep far more than usual
Make an occasional wrong turn
Get lost in familiar places donrsquot remember how you got there or how to get home
Feel occasionally sad Experience rapid mood swings from tears to rage for no discernible reason
Life expectancyOn average people with Alzheimers disease live for around 8 to 10 years after they start to develop symptoms However this can vary considerably from person to person Some people with the condition will live longer than this but others will not
Alzheimers disease is not usually the actual cause of death but it is often a contributing factor For example a leading cause of death in people with Alzheimers disease is pneumonia (lung infection) which may go untreated because people with the condition often arent able to recognize that theyre ill or may not be able to tell someone they are feeling unwell
RESULTS 1203 subjects were resurveyed in 1997 and among them 124 new cases of dementia including 81 cases of AD were identified By computing the relative risk(RR) of psychosocial factors to the AD many psychosocial factors were found to be correlated with AD including blue collar occupation no job no reading or writing no taking community activities no gardening in leisure bad psychological feeling and lower education (RR gt 1) The items with high PARP gt 50 were not working no job retirement no taking community activities no reading or writing blue collar occupation and no gardening in leisure MMSE total score is a good predict for AD
Psychosocial risk factors of Alzheimers disease
Too much cake and chocolate could cause Alzheimers disease new research claims
Risk The study adds further evidence to links between diabetes and dementia
Eating too many chocolates cakes and other sugary treats could help trigger Alzheimerrsquos disease says new research
bullA study in mice found high levels of blood sugar rapidly increased rogue proteins in the body which combine and kill brain cells ultimately leading to dementia
CONTINUEDhelliphelliphelliphelliphellip
Green tea has also been proven to have beneficial effects when it comes to
Alzheimers(ALAMY)
Some famous books on Alzheimers
The 36-Hour Day fifth edition The 36-Hour by Nancy L Mace
Learning to Speak Alzheimers A Groundbrea
by Joanne Koenig Coste
The Validation Breakthrough Third Edition by Naomi Feil MSW
Alzheimers Disease What If There Was a Cu by Mary T Newport
A Caregivers Guide to Alzheimers Disease by Patricia R Callone
Creating Moments of Joy for the Person with by Jolene Brackey
Alzheimers Early Stages First Steps for F by Daniel Kuhn
Alzheimers Disease and Other Dementias - T by Nataly Rubinstein
Alzheimers For Dummies by Patricia B Smith
Some famous person died of Alzheimers
Fantasy author Sir Terry Pratchett dies at 66
Sir Terry Pratchett renowned fantasy author of more than 70 books has died at age 66
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
bull Generally it is diagnosed in people over 65 years of age although the less-prevalent early onset of Alzheimerrsquos can occur much earlier
bull In 2006 there were 266 million sufferers worldwide
bull Alzheimerrsquos is predicted to affect 1 in 85 people globally by 2050
Signs Of Normal Change vs Early Alzheimerrsquos Symptoms
Normal Early Alzheimerrsquos Disease
Canrsquot find your keys Routinely place important items in odd places such as keys in the fridge wallet in the dishwasher
Search for casual names and words
Forget names of family members and common objects or substitute words with inappropriate ones
Briefly forget conversation details
Frequently forget entire conversations
Feel the cold more Dress regardless of the weather wear several skirts on a warm day or shorts in a snow storm
Canrsquot find a recipe Canrsquot follow recipe directions
Forget to record a check Can no longer manage checkbook balance figures solve problems or think abstractly
Cancel a date with friends Withdraw from usual interests and activities sit in front of the TV for hours sleep far more than usual
Make an occasional wrong turn
Get lost in familiar places donrsquot remember how you got there or how to get home
Feel occasionally sad Experience rapid mood swings from tears to rage for no discernible reason
Life expectancyOn average people with Alzheimers disease live for around 8 to 10 years after they start to develop symptoms However this can vary considerably from person to person Some people with the condition will live longer than this but others will not
Alzheimers disease is not usually the actual cause of death but it is often a contributing factor For example a leading cause of death in people with Alzheimers disease is pneumonia (lung infection) which may go untreated because people with the condition often arent able to recognize that theyre ill or may not be able to tell someone they are feeling unwell
RESULTS 1203 subjects were resurveyed in 1997 and among them 124 new cases of dementia including 81 cases of AD were identified By computing the relative risk(RR) of psychosocial factors to the AD many psychosocial factors were found to be correlated with AD including blue collar occupation no job no reading or writing no taking community activities no gardening in leisure bad psychological feeling and lower education (RR gt 1) The items with high PARP gt 50 were not working no job retirement no taking community activities no reading or writing blue collar occupation and no gardening in leisure MMSE total score is a good predict for AD
Psychosocial risk factors of Alzheimers disease
Too much cake and chocolate could cause Alzheimers disease new research claims
Risk The study adds further evidence to links between diabetes and dementia
Eating too many chocolates cakes and other sugary treats could help trigger Alzheimerrsquos disease says new research
bullA study in mice found high levels of blood sugar rapidly increased rogue proteins in the body which combine and kill brain cells ultimately leading to dementia
CONTINUEDhelliphelliphelliphelliphellip
Green tea has also been proven to have beneficial effects when it comes to
Alzheimers(ALAMY)
Some famous books on Alzheimers
The 36-Hour Day fifth edition The 36-Hour by Nancy L Mace
Learning to Speak Alzheimers A Groundbrea
by Joanne Koenig Coste
The Validation Breakthrough Third Edition by Naomi Feil MSW
Alzheimers Disease What If There Was a Cu by Mary T Newport
A Caregivers Guide to Alzheimers Disease by Patricia R Callone
Creating Moments of Joy for the Person with by Jolene Brackey
Alzheimers Early Stages First Steps for F by Daniel Kuhn
Alzheimers Disease and Other Dementias - T by Nataly Rubinstein
Alzheimers For Dummies by Patricia B Smith
Some famous person died of Alzheimers
Fantasy author Sir Terry Pratchett dies at 66
Sir Terry Pratchett renowned fantasy author of more than 70 books has died at age 66
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Signs Of Normal Change vs Early Alzheimerrsquos Symptoms
Normal Early Alzheimerrsquos Disease
Canrsquot find your keys Routinely place important items in odd places such as keys in the fridge wallet in the dishwasher
Search for casual names and words
Forget names of family members and common objects or substitute words with inappropriate ones
Briefly forget conversation details
Frequently forget entire conversations
Feel the cold more Dress regardless of the weather wear several skirts on a warm day or shorts in a snow storm
Canrsquot find a recipe Canrsquot follow recipe directions
Forget to record a check Can no longer manage checkbook balance figures solve problems or think abstractly
Cancel a date with friends Withdraw from usual interests and activities sit in front of the TV for hours sleep far more than usual
Make an occasional wrong turn
Get lost in familiar places donrsquot remember how you got there or how to get home
Feel occasionally sad Experience rapid mood swings from tears to rage for no discernible reason
Life expectancyOn average people with Alzheimers disease live for around 8 to 10 years after they start to develop symptoms However this can vary considerably from person to person Some people with the condition will live longer than this but others will not
Alzheimers disease is not usually the actual cause of death but it is often a contributing factor For example a leading cause of death in people with Alzheimers disease is pneumonia (lung infection) which may go untreated because people with the condition often arent able to recognize that theyre ill or may not be able to tell someone they are feeling unwell
RESULTS 1203 subjects were resurveyed in 1997 and among them 124 new cases of dementia including 81 cases of AD were identified By computing the relative risk(RR) of psychosocial factors to the AD many psychosocial factors were found to be correlated with AD including blue collar occupation no job no reading or writing no taking community activities no gardening in leisure bad psychological feeling and lower education (RR gt 1) The items with high PARP gt 50 were not working no job retirement no taking community activities no reading or writing blue collar occupation and no gardening in leisure MMSE total score is a good predict for AD
Psychosocial risk factors of Alzheimers disease
Too much cake and chocolate could cause Alzheimers disease new research claims
Risk The study adds further evidence to links between diabetes and dementia
Eating too many chocolates cakes and other sugary treats could help trigger Alzheimerrsquos disease says new research
bullA study in mice found high levels of blood sugar rapidly increased rogue proteins in the body which combine and kill brain cells ultimately leading to dementia
CONTINUEDhelliphelliphelliphelliphellip
Green tea has also been proven to have beneficial effects when it comes to
Alzheimers(ALAMY)
Some famous books on Alzheimers
The 36-Hour Day fifth edition The 36-Hour by Nancy L Mace
Learning to Speak Alzheimers A Groundbrea
by Joanne Koenig Coste
The Validation Breakthrough Third Edition by Naomi Feil MSW
Alzheimers Disease What If There Was a Cu by Mary T Newport
A Caregivers Guide to Alzheimers Disease by Patricia R Callone
Creating Moments of Joy for the Person with by Jolene Brackey
Alzheimers Early Stages First Steps for F by Daniel Kuhn
Alzheimers Disease and Other Dementias - T by Nataly Rubinstein
Alzheimers For Dummies by Patricia B Smith
Some famous person died of Alzheimers
Fantasy author Sir Terry Pratchett dies at 66
Sir Terry Pratchett renowned fantasy author of more than 70 books has died at age 66
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Forget to record a check Can no longer manage checkbook balance figures solve problems or think abstractly
Cancel a date with friends Withdraw from usual interests and activities sit in front of the TV for hours sleep far more than usual
Make an occasional wrong turn
Get lost in familiar places donrsquot remember how you got there or how to get home
Feel occasionally sad Experience rapid mood swings from tears to rage for no discernible reason
Life expectancyOn average people with Alzheimers disease live for around 8 to 10 years after they start to develop symptoms However this can vary considerably from person to person Some people with the condition will live longer than this but others will not
Alzheimers disease is not usually the actual cause of death but it is often a contributing factor For example a leading cause of death in people with Alzheimers disease is pneumonia (lung infection) which may go untreated because people with the condition often arent able to recognize that theyre ill or may not be able to tell someone they are feeling unwell
RESULTS 1203 subjects were resurveyed in 1997 and among them 124 new cases of dementia including 81 cases of AD were identified By computing the relative risk(RR) of psychosocial factors to the AD many psychosocial factors were found to be correlated with AD including blue collar occupation no job no reading or writing no taking community activities no gardening in leisure bad psychological feeling and lower education (RR gt 1) The items with high PARP gt 50 were not working no job retirement no taking community activities no reading or writing blue collar occupation and no gardening in leisure MMSE total score is a good predict for AD
Psychosocial risk factors of Alzheimers disease
Too much cake and chocolate could cause Alzheimers disease new research claims
Risk The study adds further evidence to links between diabetes and dementia
Eating too many chocolates cakes and other sugary treats could help trigger Alzheimerrsquos disease says new research
bullA study in mice found high levels of blood sugar rapidly increased rogue proteins in the body which combine and kill brain cells ultimately leading to dementia
CONTINUEDhelliphelliphelliphelliphellip
Green tea has also been proven to have beneficial effects when it comes to
Alzheimers(ALAMY)
Some famous books on Alzheimers
The 36-Hour Day fifth edition The 36-Hour by Nancy L Mace
Learning to Speak Alzheimers A Groundbrea
by Joanne Koenig Coste
The Validation Breakthrough Third Edition by Naomi Feil MSW
Alzheimers Disease What If There Was a Cu by Mary T Newport
A Caregivers Guide to Alzheimers Disease by Patricia R Callone
Creating Moments of Joy for the Person with by Jolene Brackey
Alzheimers Early Stages First Steps for F by Daniel Kuhn
Alzheimers Disease and Other Dementias - T by Nataly Rubinstein
Alzheimers For Dummies by Patricia B Smith
Some famous person died of Alzheimers
Fantasy author Sir Terry Pratchett dies at 66
Sir Terry Pratchett renowned fantasy author of more than 70 books has died at age 66
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Life expectancyOn average people with Alzheimers disease live for around 8 to 10 years after they start to develop symptoms However this can vary considerably from person to person Some people with the condition will live longer than this but others will not
Alzheimers disease is not usually the actual cause of death but it is often a contributing factor For example a leading cause of death in people with Alzheimers disease is pneumonia (lung infection) which may go untreated because people with the condition often arent able to recognize that theyre ill or may not be able to tell someone they are feeling unwell
RESULTS 1203 subjects were resurveyed in 1997 and among them 124 new cases of dementia including 81 cases of AD were identified By computing the relative risk(RR) of psychosocial factors to the AD many psychosocial factors were found to be correlated with AD including blue collar occupation no job no reading or writing no taking community activities no gardening in leisure bad psychological feeling and lower education (RR gt 1) The items with high PARP gt 50 were not working no job retirement no taking community activities no reading or writing blue collar occupation and no gardening in leisure MMSE total score is a good predict for AD
Psychosocial risk factors of Alzheimers disease
Too much cake and chocolate could cause Alzheimers disease new research claims
Risk The study adds further evidence to links between diabetes and dementia
Eating too many chocolates cakes and other sugary treats could help trigger Alzheimerrsquos disease says new research
bullA study in mice found high levels of blood sugar rapidly increased rogue proteins in the body which combine and kill brain cells ultimately leading to dementia
CONTINUEDhelliphelliphelliphelliphellip
Green tea has also been proven to have beneficial effects when it comes to
Alzheimers(ALAMY)
Some famous books on Alzheimers
The 36-Hour Day fifth edition The 36-Hour by Nancy L Mace
Learning to Speak Alzheimers A Groundbrea
by Joanne Koenig Coste
The Validation Breakthrough Third Edition by Naomi Feil MSW
Alzheimers Disease What If There Was a Cu by Mary T Newport
A Caregivers Guide to Alzheimers Disease by Patricia R Callone
Creating Moments of Joy for the Person with by Jolene Brackey
Alzheimers Early Stages First Steps for F by Daniel Kuhn
Alzheimers Disease and Other Dementias - T by Nataly Rubinstein
Alzheimers For Dummies by Patricia B Smith
Some famous person died of Alzheimers
Fantasy author Sir Terry Pratchett dies at 66
Sir Terry Pratchett renowned fantasy author of more than 70 books has died at age 66
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
RESULTS 1203 subjects were resurveyed in 1997 and among them 124 new cases of dementia including 81 cases of AD were identified By computing the relative risk(RR) of psychosocial factors to the AD many psychosocial factors were found to be correlated with AD including blue collar occupation no job no reading or writing no taking community activities no gardening in leisure bad psychological feeling and lower education (RR gt 1) The items with high PARP gt 50 were not working no job retirement no taking community activities no reading or writing blue collar occupation and no gardening in leisure MMSE total score is a good predict for AD
Psychosocial risk factors of Alzheimers disease
Too much cake and chocolate could cause Alzheimers disease new research claims
Risk The study adds further evidence to links between diabetes and dementia
Eating too many chocolates cakes and other sugary treats could help trigger Alzheimerrsquos disease says new research
bullA study in mice found high levels of blood sugar rapidly increased rogue proteins in the body which combine and kill brain cells ultimately leading to dementia
CONTINUEDhelliphelliphelliphelliphellip
Green tea has also been proven to have beneficial effects when it comes to
Alzheimers(ALAMY)
Some famous books on Alzheimers
The 36-Hour Day fifth edition The 36-Hour by Nancy L Mace
Learning to Speak Alzheimers A Groundbrea
by Joanne Koenig Coste
The Validation Breakthrough Third Edition by Naomi Feil MSW
Alzheimers Disease What If There Was a Cu by Mary T Newport
A Caregivers Guide to Alzheimers Disease by Patricia R Callone
Creating Moments of Joy for the Person with by Jolene Brackey
Alzheimers Early Stages First Steps for F by Daniel Kuhn
Alzheimers Disease and Other Dementias - T by Nataly Rubinstein
Alzheimers For Dummies by Patricia B Smith
Some famous person died of Alzheimers
Fantasy author Sir Terry Pratchett dies at 66
Sir Terry Pratchett renowned fantasy author of more than 70 books has died at age 66
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Too much cake and chocolate could cause Alzheimers disease new research claims
Risk The study adds further evidence to links between diabetes and dementia
Eating too many chocolates cakes and other sugary treats could help trigger Alzheimerrsquos disease says new research
bullA study in mice found high levels of blood sugar rapidly increased rogue proteins in the body which combine and kill brain cells ultimately leading to dementia
CONTINUEDhelliphelliphelliphelliphellip
Green tea has also been proven to have beneficial effects when it comes to
Alzheimers(ALAMY)
Some famous books on Alzheimers
The 36-Hour Day fifth edition The 36-Hour by Nancy L Mace
Learning to Speak Alzheimers A Groundbrea
by Joanne Koenig Coste
The Validation Breakthrough Third Edition by Naomi Feil MSW
Alzheimers Disease What If There Was a Cu by Mary T Newport
A Caregivers Guide to Alzheimers Disease by Patricia R Callone
Creating Moments of Joy for the Person with by Jolene Brackey
Alzheimers Early Stages First Steps for F by Daniel Kuhn
Alzheimers Disease and Other Dementias - T by Nataly Rubinstein
Alzheimers For Dummies by Patricia B Smith
Some famous person died of Alzheimers
Fantasy author Sir Terry Pratchett dies at 66
Sir Terry Pratchett renowned fantasy author of more than 70 books has died at age 66
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Eating too many chocolates cakes and other sugary treats could help trigger Alzheimerrsquos disease says new research
bullA study in mice found high levels of blood sugar rapidly increased rogue proteins in the body which combine and kill brain cells ultimately leading to dementia
CONTINUEDhelliphelliphelliphelliphellip
Green tea has also been proven to have beneficial effects when it comes to
Alzheimers(ALAMY)
Some famous books on Alzheimers
The 36-Hour Day fifth edition The 36-Hour by Nancy L Mace
Learning to Speak Alzheimers A Groundbrea
by Joanne Koenig Coste
The Validation Breakthrough Third Edition by Naomi Feil MSW
Alzheimers Disease What If There Was a Cu by Mary T Newport
A Caregivers Guide to Alzheimers Disease by Patricia R Callone
Creating Moments of Joy for the Person with by Jolene Brackey
Alzheimers Early Stages First Steps for F by Daniel Kuhn
Alzheimers Disease and Other Dementias - T by Nataly Rubinstein
Alzheimers For Dummies by Patricia B Smith
Some famous person died of Alzheimers
Fantasy author Sir Terry Pratchett dies at 66
Sir Terry Pratchett renowned fantasy author of more than 70 books has died at age 66
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Green tea has also been proven to have beneficial effects when it comes to
Alzheimers(ALAMY)
Some famous books on Alzheimers
The 36-Hour Day fifth edition The 36-Hour by Nancy L Mace
Learning to Speak Alzheimers A Groundbrea
by Joanne Koenig Coste
The Validation Breakthrough Third Edition by Naomi Feil MSW
Alzheimers Disease What If There Was a Cu by Mary T Newport
A Caregivers Guide to Alzheimers Disease by Patricia R Callone
Creating Moments of Joy for the Person with by Jolene Brackey
Alzheimers Early Stages First Steps for F by Daniel Kuhn
Alzheimers Disease and Other Dementias - T by Nataly Rubinstein
Alzheimers For Dummies by Patricia B Smith
Some famous person died of Alzheimers
Fantasy author Sir Terry Pratchett dies at 66
Sir Terry Pratchett renowned fantasy author of more than 70 books has died at age 66
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Some famous books on Alzheimers
The 36-Hour Day fifth edition The 36-Hour by Nancy L Mace
Learning to Speak Alzheimers A Groundbrea
by Joanne Koenig Coste
The Validation Breakthrough Third Edition by Naomi Feil MSW
Alzheimers Disease What If There Was a Cu by Mary T Newport
A Caregivers Guide to Alzheimers Disease by Patricia R Callone
Creating Moments of Joy for the Person with by Jolene Brackey
Alzheimers Early Stages First Steps for F by Daniel Kuhn
Alzheimers Disease and Other Dementias - T by Nataly Rubinstein
Alzheimers For Dummies by Patricia B Smith
Some famous person died of Alzheimers
Fantasy author Sir Terry Pratchett dies at 66
Sir Terry Pratchett renowned fantasy author of more than 70 books has died at age 66
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
The 36-Hour Day fifth edition The 36-Hour by Nancy L Mace
Learning to Speak Alzheimers A Groundbrea
by Joanne Koenig Coste
The Validation Breakthrough Third Edition by Naomi Feil MSW
Alzheimers Disease What If There Was a Cu by Mary T Newport
A Caregivers Guide to Alzheimers Disease by Patricia R Callone
Creating Moments of Joy for the Person with by Jolene Brackey
Alzheimers Early Stages First Steps for F by Daniel Kuhn
Alzheimers Disease and Other Dementias - T by Nataly Rubinstein
Alzheimers For Dummies by Patricia B Smith
Some famous person died of Alzheimers
Fantasy author Sir Terry Pratchett dies at 66
Sir Terry Pratchett renowned fantasy author of more than 70 books has died at age 66
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Alzheimers Disease What If There Was a Cu by Mary T Newport
A Caregivers Guide to Alzheimers Disease by Patricia R Callone
Creating Moments of Joy for the Person with by Jolene Brackey
Alzheimers Early Stages First Steps for F by Daniel Kuhn
Alzheimers Disease and Other Dementias - T by Nataly Rubinstein
Alzheimers For Dummies by Patricia B Smith
Some famous person died of Alzheimers
Fantasy author Sir Terry Pratchett dies at 66
Sir Terry Pratchett renowned fantasy author of more than 70 books has died at age 66
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Alzheimers Early Stages First Steps for F by Daniel Kuhn
Alzheimers Disease and Other Dementias - T by Nataly Rubinstein
Alzheimers For Dummies by Patricia B Smith
Some famous person died of Alzheimers
Fantasy author Sir Terry Pratchett dies at 66
Sir Terry Pratchett renowned fantasy author of more than 70 books has died at age 66
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Some famous person died of Alzheimers
Fantasy author Sir Terry Pratchett dies at 66
Sir Terry Pratchett renowned fantasy author of more than 70 books has died at age 66
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Fantasy author Sir Terry Pratchett dies at 66
Sir Terry Pratchett renowned fantasy author of more than 70 books has died at age 66
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Film Producer Actor Singer
Ronald Reagan Spokesperson Politician Soldier
James Stewart Pilot Television director Military Officer
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Charlton Heston Actor Voice acting Political Activist
Charles Bronson Miner Soldier Actor
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Some food inducing memory loss
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Foods That Induce Memory Loss
Unfortunately the foods that hamper memory are common staples in the American diet White breads pasta processed meats and cheeses all of these have been linked to Alzheimerrsquos disease Some experts have even found that whole grain breads are as bad as white breads because they spike blood sugar which causes inflammation
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Processed cheeses
Processed meats
Beer
White foods
Microwave popcorn
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Healthy Foods That Boost Memory
bullLeafy green vegetables
bullSalmon and other cold-water fish
bullBerries and dark-skinned fruits
bullCoffee and chocolate
bullExtra virgin olive oil
bullCold-pressed virgin coconut oil
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
High plasma levels of vitamin E forms and reduced Alzheimers disease risk in advanced age
Mangialasche F1 Kivipelto M Mecocci P Rizzuto D Palmer K Winblad B Fratiglioni L
In conclusion high plasma levels of vitamin E are associated with a reduced risk of AD in advanced age The neuroprotective effect of vitamin E seems to be related to the combination of different forms rather than to alpha-tocopherol alone whose efficacy in interventions against AD is currently debated
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Exposure to DDT linked to increased risk of Alzheimers disease in elderly adultsMonday February 03 2014 by LJ Devon Staff Writer
DDT pesticide increases nerve cell plaque associated with Alzheimers Alzheimers is characterized by plaque formation between nerve cells which leads to massive nerve cell die-offs Increased amyloid protein permits the plaque to form
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Pomegranate juice shown to halt Alzheimers disease progressionWednesday October 04 2006 by Jessica Fraser
This study is the first to show beneficial effects (both behavioral and neuropathological) of pomegranate juice in an animal model of (Alzheimers disease) wrote lead researcher Richard Hartman Hartman and his research team wrote that because pomegranate juice is so rich in biochemical compounds that may act synergistically to produce Alzheimers protection
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Direct link discovered between eating fish and preventing Alzheimers disease
Wednesday November 30 2011 by S L Baker features writer
The results showed that people who consumed baked or broiled fish at least one time per week had better preservation of gray matter volume on MRI in brain areas at risk for Alzheimers disease
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Hibernating Animals Might Provide Clues For Fighting AlzheimersThe Huffington Post | By Carolyn Gregoire
Research from Leicester University have isolated a cold-activated protein RBM3 which helps restore brain activity of animals that are coming out of long hibernation periods Though the protein also exists in humans its been found to be missing among Alzheimers patients whose brains also commonly have a reduced number of synapses
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
Deaths Rate World Rank
10808 1433 085 20
Pakistan AlzheimersDementia
According to the latest WHO data published in April 2011 AlzheimersDementia Deaths in Pakistan reached 10808 or 085 of total deaths The age adjusted Death Rate is 1433 per 100000 of population ranks Pakistan 20 in the world Review other causes of death by clicking the links below or choose the full health profile
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwnaturalnewscom037044_obesity_cognitive_decline_Alzheimershtml
httpwwwnaturalnewscom041717_green_tea_red_wine_Alzheimers_preventionhtml
httpwwwnaturalnewscom042632_vitamin_D3_Alzheimers_prevention_prohormonehtml
httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
httpwwwdouglasqccainfoalzheimer-causes-symptoms
httpswwwalzdiscoveryorgnews-roomviewthe-psychological-risk-factors-for-dementia
httpwwwhelpguideorgarticlesalzheimers-dementiaalzheimers-diseasehtm httpwwwnhsukConditionsAlzheimers-diseasePagesIntroductionaspx
