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04l08/2010 18:27 FAX IgJ UU<::/ VUJ
.NMSI LABS 1
CONFIDENTIALNMS Labs3701 Wels/'! Road, PO Box 433A, WillOWGrove. PA 19090-0437
PhOne: (215) 657-4900 Fax: (215) 657-2972a-mall: nms@nmSla!)S.COm
RobertA. Middleberg. PhD. DA8FT, DABCC-TC. LabClratory Director
Toxicology ReportReport Issued 04/06120101B:20Last Report Issued 04/06/201016:00
Patient NamePatient 10ChainAgeGenderWorkorder
Page' or4
MALENKO, MILANP100615213YFemale10061521To: M60403
Northern Sun Family Health Care53 Main Street
Topsham, ME 04086
Positive Findings:
.l.!.rl1ti Matrl~ SQUL~
UrineUrineUrine
Result
SEE COMMENTPQsitiYe6&
Compound
OIL Methamphetamine RatioTheobromineMethamphetamine
mcg/mLng/mL
See Detailed Findings section for eddltlonallnforrnation
Testing Requested:
Analysis Code DescrIptIon
0329U1452U6945H
Amphetamines (DIl RatiO)~TIrlneDrug-Facilitated Sexual Assault Survey 2, Urine (Forensic)Drug Screen 5, Hair (Forel'lSic)
Specimens Received:
ID TuboJContaim:r VolumelMasa
Matrix SOUn:1I MigcellaneoU!aInformation
CollectionDBtelTime
001 White Plastic Container002 White Envelope
03114/201016:3003/11(201016:00
UrineHead Hair
40mL0.677 9
All sample volumes/weights are approximations.
specmens received on 03/1612010.
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04/08/2010 18:27 FAX 19JUU6/UU:J
.NMSCONFIDENTIAL. Workonjer 10061521
Chain 10061521Patient 10 NP
c=TAA _L-=oJPage 2 of4
Detailed Findings:Rpt.
A.nalysls and Comments Rssult Units Limit Specimen Source Anslysill By
Hair Length 19 em 002 - Head Hair ELISA
OIL Methamphetamine SEE COMMENT 001 - Urine GC/MSRatio
Present in l-forrn only.
Theobromine Positive mcgfmL 5.0 001 .. Urine GC/MS
Methamphetamine 56 ng/rnL 5.0 001 - Urine LC-MS/MS
Other than the above findings, exammatlen ofthB specimen(SI) submitted did not reveal any poslth'8 findings oftoxicolugical 61gnlflCiJnclt by procedures outlined In the accompan)'lng AniJlysls Summary.
Reference Comments:1. OIL Methamphetamine Ratio - Urine;
If the D/L Methamphetamine ratio is grealerthan 0.' 3, the Methamphetamine found is probably the result of theUSB of the DEA Schedule II CNS stimulant (d-methamphetamine).
2. Hair Length - Head Hsir
Head Hair:Hair collected from t\"le back of the head grows at a rate of appro;(imately 1 centimeter (em) per month withaome individual variability.
Body Hair:Body hair grows at a rate of approximately 0.5 centimeters (em) per month. However, because body hair has alonger period of growth latency, the period of time represented by any portion of body hair Is more variable thewfor head hair.
3. Methamphetamine - Urine:
d-Methamphetarnlne Is a DEA schedule II stimulant drug capable of causing hallucinations, aggressivebehavior and irrational reactions. Chemically, there are two forms (isomers) Of methamphetamine: 1- and d-methamphetamine. The l-isomer is used In non-prescription Inhalers as a decoflgBstant and has weak eNS-stimulatory activIty. The d-isomer "as been used therapeutioelly as an anore;<lgenic agent in the treatment ofobesity and has potent eNS-, cardiac- and circulatory-stimulatory ectivity. Amphetamine and norephedrine(phenylpropanolamine) are metabolites of methamphetamine. d-Methamphetamine is an abused substancebecause of Its stimulatory effects and is also addictive.
High doses of methamphetamine can also elicit restlessness, confusion, hallUCinations, circulatory collapse andconvulsions.
4. Thsobromme (xanmecse) - Urine:
Theobromine is a rnethylxanthine alkaloid found in tea and cocoa products and has been reported to pass intothe breast milk of nursing mothers. Theobromine has the general properties of the xanthinea, including diuresisand smooth muscle stimulation.
Chain of custody documentation has been maintained for the analyses performed by NMS Labe.
Unless alternate arrangements are made by you, the remainder of the submitted specimens will be discarded six: (6)weeks from the date of this report; and generated data will be discarded five (5) year!! from the date the analyses wereperformed.
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6NMS[ __ I ABS I
CONFIDENTIAL
Analysis Summary and Reporting Limits:
Acode 0329U -Amphetarnines (DfL Ratio), Urine
WorkorderChaInPatient 10
1006152110061521NP
Page 3 of 4
Workorder 10061521 was electronicallysigned on 04/06/2010 15:07 by:
...- ---------)./1 .
C/ .Laura M. Labay, Ph.D., DABFTForensic Toxicologist
-Analysis by Gas CnrornatographylMess Spectrometry (GC/MS) for:
~ompou[ld
OfLArnphBtamine Ratio
Rpl. Limit
N/A
ComoounQ
OIL Methamphetamine Ratio
Rpt. Limit
NfA
-Analysis by Enzyme Immunoassay (EIA) for:
Acode 1452U - Drug-Facilitated Sexual Assault Survey 2. Urine (Forensic)
Compound
Barbiturates
Bel1zodiazepinas
CannabinoidsCocaine I Metabolites
Rpt. JJmll0.30 mcg/mL
50 ngfmL20 ng/mL
300 ng/mL
Compound
Methadone
OpiatesPhencyc!icline
Propoxyphene
Bpl, Lirnit
300 ng/rnL
300 ngfrnL
25 ngfmL
300 ng/mL
-Analysis by Gas Chromatography/Mass Spectrometry (GC/MS) for:
Compound
Gamrna-Hydroxybutync Acid
Bot. Limit
2.0 mcg/mL
Compound Rpt l jrojt
-Analysis by Gas Chromatography/Mass Spectrometry (GC/MS) for: The following is a general list of compoundclasses included in the Gas Chromatographic sCreen. The detection of any particular compound is concentration-dependent. Please note that not all known compounds inclucled in each specified class or heading are Induded.Soma specific compounds outside these classes are also included. For a detailed list of all compounds endreporting limits included in this screen, please contact NMS Laba.
Amphetamines, Analgesics (opioid and non-optoid), Anorectics, Anesthetics, Antlarrhythmics, AnticholinergicAgents, Anticoagulant Agents, Anticonvulsant Agents, Antidepressants, Antiemetic Agents. Antifungal Agents,Antihistamines, Antihypertensive Agents, Antiparkinscnian Agents, Antipsychotic Agents, Antitussive Agents,Antiviral Agents. Anxlolytlcs (Benzodiazepine and others). Calcium Channel Bloc::king Agents, CardiovascularAgants (non-<ligitalis), Hallucinogens, Hypnosedafives (Baroituratee, NOn-Benzodiazapine Hypnotics, andothers). Local Anesthetics Agents, Muscle Relal(ants, Non-Steroidal Anti-Inflammatory Agents (exc::ludingSalicylate} and Stimulants (Amphetamine.liKe and others).
-Anaiysis by Hsadspaca Gas Chromatography (GC) for:
Compound Rpt. LimitAcetone 1.0 mgfdL
Ethanol 10 mgfdL
Comoound
. lsopropanolMethanol
BpI. Limit1.0 mgfdL5.0 mg/dL
-Analysis by High Performance Liquid ChromatographyfTandem Mass Spectrometry (LC-MS/MS) for:
Compound
7-Arnino Clonazeparn7-Amino Flunitrazepam
Rpt. Limit
2.0 ngfmL
2.0 ngfmL
Compound
7·Amino Nitrazepam
Clonazeparn
Rpt. Limit
2.0 ngfmL2.0 ng/mL
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04/08/2010 18:28 FAX i,® UU:JI UU:J
\i
6NMSC tABS i
CONFIDENTIAL WorkorderChainPatient 10
1006152110061521NP
Page 40f4
Analysis Summary and Reporting Limits:Compouod . Rpt Limit
Flunitrazeparn 2.0 ng/ml
Nitrazeparn 2.0 ng/mL
-Analysis by High Performance Liquid ChromatographylTandem Mass Spectrometry (LC-MS/MS) for
Compound Rot. Limit Compound
1-Hydroxymidazolam 5.0 ng/mL EstazotarnAlpha-Hydro)(yalprazolam 10 ngfmL Hydroxyethylflurazapam
Alprazolarn 5.0 ng/ml Hyoroxytrtaaolam
Cnlordiazepoxide 20 ngfml LorazeparnClobazarn 20 ngfmL Nordlazepam
Desalkyltlurazepam 5.0 ng/ml OxazepamDiazepam 20 ngfml Temalepam
Compound
Nortlunltrazepam
Rpt. Limit
2.0 nglrnL
Rpt. Umit
5.0 ng/mL
5.0 ngfmL5.0ogfmL10 ng/ml
20 ng/mL20 nglmL
20 ng/mL
Acode 500,OU -Amphetamines Confirmation, Urine (Forensic)
-Analysis by High Performance Liquid Chromatographyrrandem Mass Spectrometry (lC-MS/MS) for:
Compound
AmphetamineEphedrineMDA
MDEAMDMAMethamphetamineMethylephedrine
Rpt. Limit
5.0 ng/ml
5.0og/mL5.0og/ml
10 ngfmL
5.0 ngfmL5.0 ng/mL5.0 nglmL
Compoynd
Norpseudoephedrine
PhendimetrazmePhenmetrazl nePhentermiOe
Phenylpropanolamine
Pseudoephedrine
Selegiline
Rot. Limit
5.0 ng/mL10 ng/mL
5.0 ng/mL
10 ng/ml
5.0 ng/mL
5.0 ng/ml5.0 ngfmL
Acode 6945H • Drug Screen 5, Hair (Forensic) - Head Hair
-Anatysis by Enzyme-Linked Imrnunosorbent Assay (ELISA) ror:
~(lWQynd
Amphetamines
Barbiturates
Benzodiazeplaes
Rot. Limit
430 ng/g'70 ngfg260 n9/g
Bpt Limit430 ng/g
0.26 mcg/g
260 ng/g
Compound
Cocaine f Metabolites
OpiatesPhencyclidine
-Analysis by Gas Chromatography/Mass Spectrometry (GC/MS) for: GC/MS Hair Drug Screen Extracts for:Belladonna-, Clnchona-. Methylxanthlne- and Strychnos-Alkaloids; Amphetamine and Amphetamine-likeSympathomlmetics: Antihistamines; Antipsychotics (Including Phenothlazlnes. Tn- and Tetracyclics); Non-Barbiturate Hypnosedatives; LOeB' anasthattcs: Muscle Relaxants: Non-Digitalis Cardioregulatories; Non-lSDHallucinogens; Synthetic AnticholinerQics; Synthetic Morphine; Substitute Narcotic Analgesics; Ketamine;Methdllazlne: Tlletamlne and Trimethobenzamide.
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