Missouri Regional Life Sciences Summit Business Journal Supplement

An Advertising supplement to the KAnsAs City And st. louis Business JournAls

2 | missouri regionAl life sCienCes summit An Advertising supplement to the KAnsAs City And st. louis Business JournAls

Summit scheduleSunday, March 7

5 to 9 p.m. Exhibitor and poster setup, early re istra on

Event oca onTimeUMKC Swinney Recrea�on Center

Monday, March 8

6:30 a.m. Exhibit and poster setup

EventTime

e istra on opens

Exhibits and poster session interac on

8 a.m. Welcome UMKC Pierson Auditorium

8:30 a.m. Keynote Speaker: William H. Danforth, chancellor emeritus, Washington University: “Partnerships for Progress in Health and Economic Development”

oca onUMKC Swinney Recrea�on Center

UMKC Swinney Recrea�on Center

UMKC Pierson Auditorium

9:15 a.m. is n uished Speaker: Sco� Peterson, director of func�onal genomics research technology, professor, J. Craig Venter Ins�tute: “Synthe�c Biology in an Era of Personalized Medicine”


10 a.m. is n uished Speaker: Krzysztof Ptak, Office of Cancer Nanotechnology ResearchCenter for Strategic and Scien�c Ini�a�ves; Office of the Director, Na�onal Cancer Ins�tute/ NIH: “NCI Alliance for Nanotechnology in Cancer: Achievement and Path Forward”


11 a.m. The Role of Life Sciences in Building Regional EconomyLegisla�ve and government panel featuring leaders from Missouri General Assembly and regional leaders


12:15 p.m. Lunch with David W. Kemper, chairman of the board, president and chief execu�ve officer of the Company and Commerce Bank N.A., Commerce Bancshares Inc.: “Venture Investment in Life Science”


1 p.m. hief Research cers anelChancellor Brady Deaton, session chair


2:30 p.m. Exhibit browsing co ee break UMKC Swinney Recrea�on Center

3:30 p.m. Scien cally Led a onal Enterprises


4:30 p.m. Building nnova ve orporatecademic artnerships: What is eeded Chancellor Leo Morton,

session chair


5:30 p.m.

Exhibits and posters close


7 p.m.

Recep on


Tuesday, March 9

7 a.m. Registra on opens

Event Loca onTimeKauffman Conference Center

8 a.m. etworking breakfast

9:15 a.m. Dis nguished Speaker

10 a.m. Breakout sessions• Transla�onal Medicine and

Nanoscience• Compu�ng Infrastructure and

Informa�cs to Support Life Sciences R&D, Therapeu�cs, Diagnos�cs and Economic Development

• Jump Star�ng and Moving New Technologies to Marketplace

• Transla�onal Vision and Neuroscience Research

• Advances in Biomaterials and Medical Devices

Kauffman Conference Center

11:30 a.m. to 12:30 p.m.

Lunch

Kauffman Conference Center, Town Square



Noon Invited Speaker: Rainer Bussmann,Director, William L. Brown Center and William L. Brown Curator of Economic Botany,Missouri Botanical Garden: “Plants for a sustainable future”


12:30 p.m. a onal Movement of linical and Transla onal Science and Drug Discovery• Jamal A. Ibdah, senior associate

dean for research and director, MU Ins�tute for Clinical and Transla�onal Science, MU

• Si�a Si�ampalam, Department of Pharmacology, Toxicology and Therapeu�cs, University of Kansas Medical Center


1:30 p.m. Breakout Sessions• Compara�ve Medicine:

Innova�ons for the Animal to Human Health Corridor

• Func�onal Brain Imaging and New Fron�ers of Neuroscience

• Patent Issues Rela�ve to Life Sciences R&D – Moving from Discovery in Academia to Commercializa�on

• Biomedical Tissue Engineering – Where We Go in the Future

• Public-Private Partnerships for One Health


3 p.m. nimal to uman ealth ollabora ons: The ath orward • Gary D. Forsee, president, University of Missouri System • Brady Deaton, chancellor, MU• Leo Morton, chancellor, UMKC • Robert Duncan, vice chancellor for research, MU• Bob Marcusse, president and CEO,

Kansas City Area Development Council

7 a.m. UMKC Swinney Recrea�on Center

10:30 a.m. Dis nguished Speaker: Thomas C. Melzer, managing director and co-founder, RiverVest: “Financial Downturn and Impact on Biosciences Development”


4 p.m. Adjourn

Schedule subject to change

on nental breakfast

Noon Speaker: Sen. Christopher “Kit” S. Bond


An Advertising supplement to the KAnsAs City And st. louis Business JournAls missouri regionAl life sCienCes summit | 3

Chief university research office presenta�ons at the summitVice Provost for ResearchUniversity of Missouri-St. Louis341 Woods Hall, 1 University Blvd. St. Louis, MO [email protected]/services/ora

ames . asi erAc�ng Associate Vice-President ResearchUniversity of SaskatchewanRm. 201.1 College Building107 Administra�on PlaceSaskatoon, SK S7N 5A2, [email protected]/vpresearch/

da . o e aldInterim Vice Chancellor for ResearchUniversity of Missouri-Kansas City2464 Charlo�eKansas City, MO 64108816-235-1520 [email protected]/research

Robert DuncanVice Chancellor for ResearchUniversity of Missouri-Columbia205 Jesse HallColumbia, MO 65211 [email protected]

Evan KharaschInterim Vice Chancellor for ResearchWashington University 660 South Euclid Avenue Campus Box 8054St. Louis, Missouri 63110314-362-7010denne�[email protected] wustl.edu/research K. KrishnamurthyVice Provost for ResearchMissouri University of Science &Technology202 Centennial Hall Rolla, MO 65409573-341-4154 [email protected] mst.edu/research

Sharron S. QuisenberryVice President for Research andEconomic DevelopmentIowa State University of Science andTechnology2610 Beardshear HallAmes, IA [email protected]

Raymond C. TaitVice President for ResearchSaint Louis University Medical Center Campus3556 Caroline St., Room 120 St. Louis, MO 63104 [email protected]/research

aul TerranovaVice Chancellor for ResearchUniversity of Kansas Medical Center3901 Rainbow Blvd., Mail Stop 2015Kansas City, KS [email protected]/research.html

R. W. TrewynVice President for ResearchKansas State University785-532-5110108 Anderson HallManha�an, KS [email protected] state.edu/kstateresearch

Steve . WarrenVice Provost for ResearchUniversity of Kansas2385 Irving Hill Rd.Lawrence, KS [email protected]/research

ary at Wohl ord WesselsExecu�ve Vice President for Research and Ins�tu�onal Effec�venessKansas City University of Medicineand Biosciences1750 Independence Ave.Kansas City, MO 64106816-283-2424 [email protected]/research

Silicon Valley in California, the Research Triangle in North Carolina and Route

128 around Boston have emerged as centers for innovation and discovery in the United States. At the heart of these regions are outstanding research universities and business communities that understand how to make the most of the opportunities that universities provide. These collaborations have shaped the products we use and the services we expect. And, the quality of life in these areas is well above the national average.

In Missouri and Kansas, we have outstanding universities where researchers are doing stellar work. At the University of Missouri, new advances in basic biosciences will impact the food we eat, the medications we take, the medical therapies we use and even the way we expend energy. Our region also is home to major businesses interested in discoveries that can be marketed to improve people’s lives.

Health care for humans and animals is becoming more integrated than ever before. New procedures and techniques that work for dogs, cats, horses and pigs are finding their way into human hospitals, while veterinarians are using diagnostics and

treatments for human diseases, including cancer, to care for their four-legged patients. Yet, the time and hurdles that scientists face to get their discoveries from the lab to the bedside can be challenging.

The region from Manhattan, Kan., to Columbia, Mo., leads the nation in animal health and nutrition research, business functions and production. This thriving Midwestern area has come to be known as the “KC Animal Health Corridor.” In addition, the huge concentration of plant and medical sciences from Kansas City to St. Louis only increases our region’s potential as a world leader in applied biosciences.

It is quite possible that 10 years from now the medicines we take will be customized for our illnesses with less risk and faster recovery. The food we eat will produce better yields and, thus, cost less. The energy we use will be cleaner, leading to better respiratory health and lower utility bills.

For these things to occur, business leaders must know about and have access to university researchers who are discovering new ideas and processes.

On March 8-9, the University of Missouri is leading a regional life sciences

summit in Kansas City to do just that. The goal of the summit is to accelerate the movement of innovations from the laboratory to the marketplace. Business leaders, legislators, scientists, university officials and representatives from other prestigious institutions and organizations will come together to identify discoveries that lead to private sector investments, job creation and hold the greatest promise for commercialization.

The potential contributions of government programs, new legislation, community college educational efforts and new business models will be discussed. The summit also will focus on how best to leverage the assets of universities, financial markets and business investments to create new companies and jobs that will strengthen the economic foundations of the region.

During these challenging economic times, the time is right for the region’s businesses and research universities to work together to improve lives. We have an opportunity to emerge as the biosciences powerhouse much like Silicon Valley, Research Triangle or Route 128. The Missouri Regional Life Sciences Summit is an important step forward.

Pu�ng the Midwest’s Bio-Innova�on Belton the mapBusinesses and research

universi es must unite for a be er economy and quality of life

Brady J. DeatonSummit ChairChancellor, University of Missouri-Columbia

Leo E. MortonSummit HostChancellor, University of Missouri-Kansas City


At KCP&L, we work hard to bring innovation, investment and job creation to the many communities we serve.

P r o u d S P o n S o r o f t h e M i S S o u r i r e g i o n a l l i f e S c i e n c e S S u M M i t

2. Cleaner, greener energyThe $164 million Spearville Wind Energy Facility began operating in 2006. It is now generating clean, renewable power to handle the annual electricity needs of about 33,000 homes. Innovative energy-efficiency programs are saving customers energy and money while offsetting demand growth and reducing emissions.

1. National leader in reliabilityIn October 2009, KCP&L was recognized by PA Consulting Group as the recipient of the 2009 ReliabilityOne™ award. This award is given annually to utilities that lead the nation in delivering reliable electric service to their customers resulting in fewer outages and faster response time. This is the third year in a row KCP&L has been honored with the award.

3. Environmentally driven ”The La Cygne project is the single largest voluntary contribution to helping the Kansas City area maintain its attainment status under the EPA’s eight-hour ozone standard.” — David Warm, Executive Director, Mid-America Regional Council

Whether supporting life sciences or managing one of the

nation’s most important SmartGrid demonstration projects,

KCP&L is driven to spur economic development for our

region and improve the lives of our more than 800,000

customers. That’s why we work closely with our partners

to provide affordable, clean and reliable energy in the

most environmentally responsible ways available.

In 2004, we developed our Comprehensive Energy Plan

with an unprecedented level of community input. Since

then, we have focused on maintaining competitive

electric rates, coupled with long-term sustainable

energy programs and environmental stewardship, to

best balance the needs of our customers – today and

into the future.

1.

2.

3.

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4. Meeting future demand, cost efficientlyIatan 2, KCP&L’s advanced technology coal-fired generation plant near Weston, Mo., will come online during 2010. This plant is an integral part of meeting future demand at the lowest reasonable cost and maintaining competitive electric rates for years to come.

5. Community focusedWe’re working to make the Kansas City area’s future brighter than ever. That’s why we provide financial support and our employees donate thousands of hours to vital community groups.

Nationally honored for community involvement and collaborationOur efforts in developing the CEP were recognized by the Edison Electric Institute, which awarded our company its highest honor for community involve-ment and collaboration. Local labor unions, neighborhood groups, elected officials, community leaders, economic development agencies and chambers of commerce endorsed the plan.

Strong investmentsBy the end of the five-year plan, KCP&L will have invested more than $1.6 billion in CEP projects. Key accomplishments include new generating capacity, envi-ronmental upgrades to existing facilities, transmission and distribution improve-ments, and energy-efficiency and afford-ability programs. In addition to Iatan 1 environmental improvements, KCP&L completed a 100-megawatt wind genera-tion project during 2006 in Spearville, Kan. The wind project, completed on time and under budget, provides KCP&L customers with a source of clean, renew-able energy. We recently issued requests for proposals to develop up to another 300 megawatts of wind generation.

Environmentally responsible energyKCP&L has demonstrated our com-mitment to providing environmentally responsible energy by making significant environmental investments at the com-pany’s La Cygne 1 and Iatan 1 generation facilities. These environmental upgrades, which were completed in 2007 and 2009 respectively, allowed KCP&L to meet new federal emission standards before being required to do so. They have had a positive impact on the Kansas City region’s air quality.

Excellence in reliability and customer serviceOngoing upgrades to KCP&L’s transmis-sion and distribution facilities are aimed at ensuring a continued high level of ma-jor systems reliability and decreasing the number and duration of outages. KCP&L encourages customers to take advantage of the residential and business energy-efficiency, affordability and demand-response programs that were introduced as part of the CEP. These initiatives allow cus-tomers to better manage electric-ity usage and control their utility costs, therefore reducing the impact of higher rates.

A Life Sciences partner in Economic Development:

MCC-Penn Valley Health Science Institute

KCP&L is honored to help support the MCC-Penn Valley Health Science Institute. This state-of-the-art education center will improve the healthcare landscape of Kansas City. By creating training resources and opportunities for Kansas City’s urban core and surrounding communities, the Institute will address the area’s critical healthcare worker shortage.

Located in a 190,000-square-foot building two blocks south of the MCC-Penn Valley campus, the Health Science Institute will allow for the expansion, enhancement and consolidation of MCC’s high-quality healthcare career programs.

With more than 20 different educational and training programs under one roof, students will experience a new kind of interdis-ciplinary, hands-on learning, using curricula that allow them to interact with one another as they would in a true clinical setting.

This fresh approach to active learning also includes expanded offerings in professional development and continuing educa-tion so health professionals can sharpen their skills and ad-vance their careers.

The Institute’s central location and expanded capacity will give urban residents and many young people from disadvantaged backgrounds greater access to comprehensive and well-supported training for high-wage, high-demand careers. K-12 educational programs will help get local youth interested in

both healthy lifestyles and careers in healthcare.

4.

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Further information about KCP&L’s Comprehensive Energy Plan is available at www.kcplenergyplan.com. For more details about our economic development community partners and business initiatives, please go to www.kcpl.com.

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The upcoming Missouri Regional Life Sciences Summit pulls regional thought leaders that influence the future of life sciences into a necessary discussion. This gathering provides all participants an opportu-nity to evaluate our region’s potential, discover new possibilities and continue to move the life sciences industries forward.

In 2006, the Kansas City region’s business, edu-cational, scientific and government communities came together to begin to promote a cluster of animal health and nutrition companies in the region between Manhattan, Kan., and Columbia, Mo. The group of businesses within that region, which represent a third of the total sales in the $19 billion global animal health industry, is the largest concentration of animal health and nutrition companies in the world.

The geographical area that contains this cluster and the regional initiative launched to support and grow it, became known as the KC Animal Health Cor-ridor.

Three regional organizations, the Greater Kansas City Chamber of Commerce, the Kansas City Area Life Sciences Institute, and the Kansas City Area Development Council applied their expertise to call attention to the existing industry while finding culti-vating future growth. Gaining the private industry’s support was necessary. Developing a vibrant animal health sector benefits each company that calls the Corridor home. It gives animal health-related busi-nesses access to a trained and talented workforce, advanced research opportunities and knowledgeable service providers.

Since its inception in 2006, the Animal Health Corridor has attracted 16 new or existing company locations. More than 220 animal health companies now have a location within the Corridor, with 70 companies having their global or U.S. headquarters here. The animal health industry has created close to 1,250 new jobs in the region and added $60.7 M in payroll.

Continuous dialogue is the root of the KC Animal Health Corridor’s success. It means having honest

conversations that work toward one goal – the recog-nition of the region as the global center of excellence for the animal sciences. The Corridor is driven by an advisory board that brings together leaders from the private industry, the top-tier veterinary programs and key regional organizations working toward that one goal.

The deans of two of the nation’s top veterinary colleges, the University of Missouri-Columbia and Kansas State University, sit on the Corridor’s advi-sory board. They are committed to work together to cultivate public and private research partnerships.

Due in large part to Kansas State University’s reputation in animal and agricultural studies, the De-partment of Homeland Security selected Manhattan as the new home for its $650 million state-of-the art research facility. The National Biosecurity and Agro Defense Facility (NBAF) should be celebrated as a teamwork success and recognized as a regional asset. The facility opens up doors to conduct research that will place our region on the map for animal and food safety.

Before the Corridor’s launch the private indus-try rarely spoke with each other. Now, networking occurs on a regular basis. Throughout the year, the Corridor sponsors and hosts key networking events designed to create productive conversations between companies, government and leading research orga-nizations. The first Missouri Regional Life Sciences Summit is one example.

The Animal Health Homecoming Dinner, recog-nized as the animal health industry’s annual dinner, has seen its attendance rise exponentially. With only 150 professionals in attendance the first year, the 2009 dinner set a record with 750 animal health industry professionals from across the U.S. The din-

ner coincides with CVC-Central, one of the nation’s largest veterinary confer-ences. With the nation’s largest companies exhib-iting at the conference, the Homecoming dinner reinforces the region’s expertise.

Last year, directly fol-lowing the Homecoming dinner, the Corridor held the first Animal Health Investment Forum. The full-day forum provided a venue for early-stage animal health companies to

present their new technologies and business plans to potential investors. These investors included capital investment firms from across the U.S. and established animal health and nutrition companies looking to expand their business. Based on the already success-ful Invest Midwest model, the forum laid founda-tions for the future of the KC animal health industry. Whether these early companies will consider the area as a location for future expansion, or an established animal health company invests in their technology, the region and industry wins.

Now in its fourth year of existence, the KC Animal Health Corridor initiative serves as one of the best case studies in regional collaboration. It has success-fully aligned two state governments, two top-tier re-search universities and a private industry comprised of competitors. Each organization, public or private, put aside individual motives to promote, and grow, something greater than them. With this base, the region has the potential to continue developing its global strength in animal health and the encompass-ing life sciences.

The Kansas City Animal Health Corridor proves regional cooperation is possible

Image provided by: The Kansas City Area Development Council

Joerg Ohle, president and general manager of Bayer HealthCare’s Animal Health Division, North

America, address more than 750 attendees at the 2009 KC Animal Health Homecoming Dinner held

in August 2009.

“..the KC Animal Health

Corridor initiative serves as one of the best case studies in regional

collaboration.

”


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10 | missouri regionAl life sCienCes summit An Advertising supplement to the KAnsAs City And st. louis Business JournAls An Advertising supplement to the KAnsAs City And st. louis Business JournAls missouri regionAl life sCienCes summit | 13


THE CHOICE OF A LAWYER IS IMPORTANT AND SHOULD NOT BE BASED SOLELY ON ADVERTISEMENTS.

For more information, contact: Andrea Sellers or Tony Strait 816.842.8600 MAIN

1201 Walnut, Suite 2900 Kansas City, MO 64106 800.846.1201 TOLL FREE Kansas City l St. Louis l Jefferson City l Overland Park l Wichita l Omaha l Washington, DC l Phoenix

At Stinson Morrison Hecker LLP, we possess the legal

acumen and technical expertise to assist life sciences

clients on their path toward innovation and growth. Simply

stated, we take the time to understand your unique

business needs. We understand the evolution of taking a

new product or method from the initial research stage to

the marketplace, but we also understand your day-to-day

business needs. From intellectual property issues and

the defense of proprietary rights, to capital formation and

mergers and acquisitions, we’ve got you covered.

Catalyst for Growth

Attorneys At Law

www.stinson.com

M odern university technology transfer began in the era of the Big Eight, with the bipar-tisan passage of the Bayh-Dole Act of 1980. For the first time, universities could own and license inventions made by research-ers using federal funding. As the Big Eight evolved into the Big 12, so did the region’s view of technology transfer. Increasingly, the life sciences community is one in which universities and industry partners routinely enter into license agreements, sponsored re-search agreements, and joint development/research/collaboration agreements. Often, these collaborations occur across state lines and between athletic conferences – between Jayhawks, Tigers, Kangaroos, their industry alumni, and beyond.

At Stinson Morrison Hecker, I have the opportunity to represent life sciences clients on both sides of the court, i.e., both universities and industry partners. I have found that initiating and negotiating university-industry partnerships can be challenging – even “maddening” – at times. Bringing key stakeholders together at events such as the Missouri Regional Life Sciences Summit is critical to building a true team approach. In this article, I will focus on the Big Eight deal terms that you can expect to see in university-industry agreements. After all, some good scouting and a little coaching never hurts this time of year.

1. License RightsIn any deal, the ultimate question is what will the uni-

versity give you? Typically, for intellectual property devel-oped solely by its researchers, don’t expect the university to assign or sell you the technology. For federally funded research, federal law prohibits such assignments. In most instances, the university will offer to license the technol-ogy – either exclusively or non-exclusively. Depending on the industry, the university may also give you the right to sublicense, although the royalty rates may be different for such sublicenses. For example, universities often require you to pay a royalty for your sublicensee’s exploitation of the technology and a percentage of any non-royalty based income that you receive from your sublicensees.

2. Reservation of RightsBy their nature, universities promote the free flow of

information and ideas. Academic institutions want to pre-serve scientists’ ability to perform research on the technol-ogy. As such, the university will typically reserve the right to practice licensed inventions and to allow other academic institutions, governmental agencies and non-profits to do the same.

3. PublicationUniversity researchers face a “publish or perish” dilemma

in terms of tenure and standing in the scientific commu-nity. Publication of research is also a necessary part of the academic mission to disseminate knowledge and promote scholarship. As such, the university will require that its re-searchers be able to publish on the technology they develop. In many instances, the university will allow the industry partner to review the manuscript prior to publication. Fur-ther, the university may permit the industry partner to seek intellectual property protection prior to publication.

4. ImprovementsAlthough industry partners generally seek guaranteed

access to future improvements on licensed inventions, it is rare that a university will agree to such terms. The obliga-tion to future improvements may cause a chilling effect on a

faculty member’s research and ability to engage in collabora-tions with other scientists. Typically, option agreements or separate future agreements are used to address the technol-ogy improvements.

5. No GuaranteesThe university will not guarantee you the right to use

the technology being licensed. With limited budgets, most universities do not have the financial resources to perform “freedom to operate” analysis. Essentially, the technology is licensed “as is.” Indeed, in many instances, the univer-sity will expressly disclaim any warranties of patent validity and non-infringement as well. To minimize exposure, the university will typically require indemnities and product liability insurance from the licensee. As state-funded insti-tutions, public universities have a duty to minimize risk to taxpayers.

6. Diligence and Commercialization Incentives

To incentivize commercial success, the university-industry agreement will often require the industry partner to develop a business plan related to the technology that includes certain reporting requirements. Further, the agree-ment may include certain diligence milestones to make sure that the technology is being developed and commercialized in a timely matter. Examples of such milestones include first prototype, regulatory approval, first commercial sale in the U.S., first commercial sale abroad, etc. For many start-ups, the diligence milestone may be related to financing as well.

7. PaymentTechnology transfer offices are typically non-profit orga-

nizations that manage the intellectual property of the univer-sity. They are typically self-funded, meaning their funding comes from revenues generated by the university licenses. The revenues are typically shared with the university itself and the faculty inventors. In most instances, compensa-tion takes the form of royalties for net revenues made on the licensed technology. The agreement may also include sign-ing fees and annual license maintenance fees. Typically, the university will also require reimbursement of patent costs in order to minimize its expenses.

8. Fame and FortuneAlthough not necessarily a deal term, you should under-

stand that some universities and their technology transfer offices are motivated by fame and fortune – but not neces-sarily in that order. Universities have a legitimate interest in enhancing the reputation of their faculty members and university research profile by showcasing the commercial success of their technologies. In addition, as non-profit organizations, the technology transfer offices often see their role as bettering the overall public good with their commer-cialization efforts.

These Big Eight deal terms should explain the univer-sity’s motivation behind certain provisions in university-in-dustry agreements. So what is your motivation to enter into the game? Universities traditionally have the most cutting-edge research tools and the brightest minds. By partnering with a university, you can gain early access to technologies typically at a cost that is much lower than technologies de-veloped elsewhere. Other arms of the university may also be able to assist you with marketing or business development. In the end, collaborations with universities in the region, and across the country, are nothing but a win-win situation.

Lana Knedlik is a registered patent attorney who practices in all areas of intellectual property law. She received her BS in chemical engineering from Kansas State University in 1993, her JD from the University of Kansas in 1996, and her BS in biology and pharmaceutical sciences from UMKC in 2002 and 2007, respectively.

The Big Eight in University-Industry PartnershipsBy Lana Knedlik

An Advertising supplement to the KAnsAs City And st. louis Business JournAls missouri regionAl life sCienCes summit | 11An Advertising supplement to the KAnsAs City And st. louis Business JournAls missouri regionAl life sCienCes summit | 13

THE CHOICE OF A LAWYER IS IMPORTANT AND SHOULD NOT BE BASED SOLELY ON ADVERTISEMENTS.

For more information, contact: Andrea Sellers or Tony Strait 816.842.8600 MAIN

1201 Walnut, Suite 2900 Kansas City, MO 64106 800.846.1201 TOLL FREE Kansas City l St. Louis l Jefferson City l Overland Park l Wichita l Omaha l Washington, DC l Phoenix

At Stinson Morrison Hecker LLP, we possess the legal

acumen and technical expertise to assist life sciences

clients on their path toward innovation and growth. Simply

stated, we take the time to understand your unique

business needs. We understand the evolution of taking a

new product or method from the initial research stage to

the marketplace, but we also understand your day-to-day

business needs. From intellectual property issues and

the defense of proprietary rights, to capital formation and

mergers and acquisitions, we’ve got you covered.

Catalyst for Growth

Attorneys At Law

www.stinson.com


man’s best friends&good for man

healthaNIMal

America loves its pets! From parakeets to Percherons, pet

owners today spend billions of dollars on the upkeep and

well-being of their animals. Interesting that prior to World

War II, very few people would consider paying more than

a token amount for the medical care of their pets. Prior

to World War I, it wouldn’t have done much good to take

your sick or injured pet to the vet: antibiotics were yet to be

developed and veterinarians that treated pets exclusively

were rare.

Pet owners continue to upgrade their purchases

Spending on pet supplies and over-the-counter medicines

continues to increase with $10 billion projected to be

spent in 2007, an increase of 6.5% over 2006, according

to the American Pet Products Manufacturers’ Association

(APPMA). Spending in 2008 exceeded $10.5 billion.

Pet services for pets grow in abundance

More than $2.9 billion was spent on pet services in

2007 according to the APPMA with spending increasing

7% in 2008. Pet owners are including their pets in their

own lifestyles so visits to the spa, exercise regimes, and

hotel-quality accommodations for day care are more

commonplace in urban areas.

Growing interest in animal healthcare

In the nation’s heartland, a serendipitous convergence

of some of the top veterinary schools and animal health

researchers and providers have joined together to cultivate

a climate of opportunity for companies competing in and

supporting the animal health and nutrition industry. What’s

happening along the “Animal Health Corridor” may be

responsive of what’s occurring throughout the country.

In the areas of diagnostics and research, high-tech

facilities are being constructed to house advanced medical

equipment. In some of the larger equine facilities, for

example, bone scans are performed using radioactive

isotopes, radiographs and ultrasound; laser surgery can

repair collapsed arytenoid cartilage; and arthroscopic

surgery can be performed to repair joints.

InteGrate For SucceSS

It’s no simple matter to design and build these increasingly

complex facilities. Over the past five years, the use of

design-build building processes to deliver higher-end

construction applications such as animal MRI facilities,

research laboratories, BSL-3 diagnostic and research

facilities, has increased dramatically. Total assimilation of the

facility’s systems is fundamental to successful production,

collection and analysis of data. Fragmented systems result

in an improperly integrated facility, a roadblock to research

and treatment of animals.

Having a thorough

understanding of building

materials, processes, and

knowledge and experience

with the specialized

laboratory mechanical,

electrical, plumbing, control

and security systems, and

integrated equipment has

contributed to the increased

use of integrated project

delivery (IPD). IPD is an

approach to project delivery

that integrates the owner, end

users, multi-disciplinary consultants, technology, business

processes and systems in a way that maximizes the specific

talents and expertise of all project stakeholders, resulting in

the delivery of a fully optimized project with increased value

and reduced waste throughout the entire project lifecycle.

Facility owners and decision makers identify the following

reasons as among those having the greatest impact on the

selection of integrated delivery as the ‘delivery method of

choice’ for their facilities:

• Shared Goals and objectivesIPD eliminates the “silo” effect in which the owner defines

a business case for development, the architect delivers a

concept, and a contractor provides estimates based on

that information. That form of traditional delivery too often

results in an adversarial state where each party looks out

for their own best interests. Through IPD, the team states

and shares common goals and objectives, with risk and

reward being shared for achieving those targets.

Cindy Rogan with Farrah & GingerJE Dunn Dallas

Jeremy Gershonowicz & Dumars JE Dunn Kansas City


• accelerated Delivery

Communication delays between the architect, engineer,

and contractor are greatly reduced with an integrated

process. Meshing design and construction efforts has

signifi cant impact on reducing the schedule by identifying

and allowing early procurement of materials, prefabrication

and long lead items. Additionally, delays due to redesign are

generally eliminated or reduced.

• early Project cost Identifi cation

The project team assembles at the formation stage of the

project optimizing the timing of input by all parties. This

allows for early and accurate project conceptualization

and establishing timely defi nition of scope and budget.

Construction cost estimates can be continually reviewed

and adjusted to refl ect changes during the design.

the KeY tO hIGh-eND DelIVeRY

“Any project delivery method undertaken needs to be

provided by a contractor that understands the intent of

the facility. Whether animal or human, understanding

the science of research and healthcare and how it

affects facility use drives building decisions. This

is very important to the success of these complex

projects as it relates to fi nal functionality,” said

Kevin Brettmann, Director of Science and Technology at

JE Dunn Construction.

JE Dunn has made a commitment to the industry by

creating the Science and Technology Center of Excellence.

Its mission is to maintain a trained in-house staff, highly

qualifi ed to execute complex construction in the healthcare

and life sciences/bioscience industry. Tasked with keeping

current on the latest trends in technology, equipment and

systems for research, the Center of Excellence devotes many

man-hours to the collection, assimilation, and utilization of

current healthcare and lifescience construction data.

PUttING KNOWleDGe tO WORK

Mechanical, electrical and plumbing intensive, laboratory

projects are typically made up of 35% or more MEP.

Consequently, given the nature of animal health construction,

JE Dunn Construction has developed a dedicated team of

estimators, engineers and coordinators who understand

lab adaptability and modular systems. To aid in the quest

for ‘no surprises,’ the team utilizes 3-D MEP computer

aided design for coordination and confl ict avoidance in a

proactive manner.

In-house staff are also able to provide procurement of long-

lead laboratory, process, and utility equipment allowing for

timely delivery within an aggressive construction schedule.

Additionally, the team utilizes an integrated commissioning

approach beginning in the design phase and maintained

through construction and occupancy.

To offer still more value to their clients, the Center of

Excellence staff is trained in the specifi cs and nuances

of science and technolgoy construction. For example, they

are trained in Labs21 classes such as “High Performance,

Low Energy Laboratory Design” and “Advanced Laboratory

Ventilation Design.”

Finally, the Build Clean program has been created,

addressing the critical requirement of minimizing, or

eliminating entirely, construction-related dust and debris

in designated ‘clean areas’ within the new facility. The

program defi nes protocol to be followed with materials

handling and transfer, construction activities, contamination

control, personnel conduct, and rules of entry within

assigned areas.

Through practical application, the Science and Technolgoy

Center of Excellence has proven exemplary training,

utilization of qualifi ed in-house staff, and the ability to tap

into the strength of a national construction organization is the

best way to deliver a world-class animal health facility.

Recent JE Dunn Construction Projects

Vet Med Equine Hospital and Lab, Iowa State University

Equine Research Center, University of Minnesota

Ted Stevens Marine Research Facility, Juneau, AK

Center for Disease Control, Ft. Collins, CO

Health Science Institute, Metropolitan Community Colleges, Kansas City

National Re-newable Energy Laboratory, Golden, CO

Cancer Research Center, Medical College of Georgia

Midwest Research Institute, Kansas City, MO

Regis University Science and Research Institute, Denver, CO

Stowers Intitute, Kansas City, MO

Interdisciplinary Life Sciences Research Institute, Texas A&M

Interdisciplinary Life Sciences Research Building, University of Kansas

Institute for Laboratory Astrophysics, University of Colorado

Bio Med Lab, University of Texas

Research requires an

intense curiosity, a unique

ability to link cause and

effect, and unbelievable

tanacity. JE Dunn brings

the same characteristics

to the construction of

research facilities.

lab rat




For more than 25 years, St. Joseph, Missouri-based Boehringer Ingelheim Vetmedica, Inc. (BIVI), has demon-strated a commitment to improv-ing the lives of animals around the

world. Through its corporate vision -- Value through Innovation -- BIVI has placed a high priority not only on scientific research and de-velopment, but also in the highly experienced technical and field services necessary to sup-port those products in the market.

In keeping with the history of Boehringer Ingelheim, innovative product research and development remains a core mission. Over the years, BIVI has made significant contributions to the animal health industry, strengthening its position as a leader in the global animal health industry and a true partner to its cus-tomer.

As part of the larger Boehringer Ingel-heim Corporation, a family-owned company founded in 1885 in Ingelheim, Germany, BIVI is committed to sustainable growth. And, it believes that growth in the area of life sciences is essential.

“We understand that to be true leaders and innovators in the market place, we need to focus our efforts on continued research and development of novel, effective solutions to our customers’ problems,” says George Heidgerken, president and COO of BIVI. “As part of these efforts, it’s critical that we seize opportunities for growth not only externally but internally as well.”

In fact in October last year, Boehringer In-gelheim closed its deal with Pfizer to acquire several widely used products from Fort Dodge

Animal Health (FDAH). “With this deal, we acquired a

number of reputable products from Fort Dodge Animal Health that fit perfectly with our long-term strategic goals,” says Heidgerken. “But just as importantly, by purchasing well-established brands that had a proven track record in the markets we needed, it allowed us to be able to explore new areas of product research and devel-opment where there is tremendous opportunity.”

In fact, Boehringer Ingelheim Animal Health invests over 12 percent of annual revenue back into research and development, placing it among the global animal health industry leaders. This gives BIVI a significant advantage in allowing them to not only find solu-tions for today’s animal diseases, but more importantly to proactively look ahead to the future for solutions to new animal health problems.

This is a strategic business move that Dr. Edward Robb, vice president of research and development for BIVI, describes in terms of a successful hockey game plan.

“To borrow a quote from Wayne Gretzky, who was honored during the Van-couver Winter Games as one of the Final Torch Lighters .‘ great players have the ability to score goals by not following the puck to where it currently is but by skating to where the puck in going to be,’” Robb says. “That’s what we have to keep in mind. Where’s the puck going to be? What will pet owners, producers and veterinarians need for their animals in the next 10 or 20 years?”

With a culture driven by product inno-vation and service excellence in each of its four business segments – pet, cattle, swine and equine -- it’s important for BIVI to make sure that the products they deliver are best in class. “How do we deliver the innovation that can create value for veterinarians, livestock producers and ranchers, pet owners and the industry? How do we discover and market those game changers?” Robb asks. “Those are the questions that drive our research and our long term business strategy.”

Novel research and product innovation are the key drivers to future BIVI growth and success. But in the end, it’s all about the dogs, cats, horses, cattle, pigs and other animals, the company provides products for. That’s what really matters.

Boehringer Ingelheim: Providing Innovation

to a Global Marketplace



UMKC

Missouri S&T

UMSL

University of Missouri System

With a $1.82 billion budget, the University of Missouri-Columbia is the state’s flagship university and one of its largest enterprises. MU’s economic impact is powerful and far reaching; the productivity of the entire state is boosted through the earning potential of Mizzou graduates, the attraction of businesses and the cumulative role of providing human capital, research and technology.

“MU is committed to putting the resources of one of the nation’s premier public research universities – with more than 31,000 students and a $320 million research operation – to work for economic development,” MU Chancellor Brady Deaton says.

During a three-year process, MU faculty, students and alumni identified the top five competitive assets, or unique strengths, that set MU apart from other universities. Collectively, these assets are called the Mizzou Advantage.

“Our competitive assets differentiate us from the biggest, best-resourced universities and allow us to do things they can’t do,” says MU Provost Brian Foster. “With more than 1,000 faculty scientists working to improve human and animal

health, food and the environment, three of these assets focus on the life sciences.”Co ss s

One Health, One Medicine: The Convergence of Human and Animal Health – Will expand on MU’s pioneering work in comparative human and animal health research, radioisotope production and nanomedicine, and connect it with expertise from medical, veterinary medicine, public health programs.

Food for the Future – Capitalizes on MU’s traditional strengths in plant and animal sciences, and a range of emerging programs such as nutrition, chronic disease research and treatment, aging and obesity.

Sustainable Energy – Will build on such strengths as MU’s research reactor—the most powerful university-operated research reactor in the United States—and programs in nuclear power generation and biofuel development.

New Media – Will draw on the School of Journalism’s century of international leadership in media research and hands-on training, along with other campus strengths in digital technologies, business, public policy, design and creative writing.

Understanding and Managing Disruptive and Transformational Technologies – Will touch on virtually every part of the university to explore areas in which existing technologies, and everything based on them, are changing rapidly. The four competitive assets listed above will act as laboratories for further research on disruptive and transformational technologies.

MU

MU physicist Peter Pfeifer holds a carbon brique�e he developed to store alterna�ve fuels, such as natural gas or hydrogen. In addi�on, MU boasts the na�on’s largest university-based nuclear reactor and is poised to be a na�onal leader in the efforts to develop reasonably priced and environmentally friendly energy. These technologies support the rapid growth of the animal health corridor by providing green energy alterna�ves.

A one-year-old golden retriever walks on a water treadmill to ease the weight on her joints a�er surgery. The path-breaking work of her veterinarian Jimi Cook, director of the MU Compara�ve Orthopaedic Laboratory, to help dogs with knee injuries has led to an FDA-approved device to treat similar injuries in humans.

The following are examples of important interdisciplinary groups.Christopher S. Bond Life Sciences Center: Improves the quality and safety of food, prevents and treats disease, and protects the environment.ntern on ns tute

of no nd Mo ecu r Medicine: Creates materials, devices and agents enhanced by nanotechnology with applica�ons in medicine and materials science. nterdiscip in r nt

Group: Studies biological processes of plants via 54 research teams from ve departments. Dalton Cardiovascular Research Center:

Develops new therapies for hypertension, cancer, cys�c brosis and heart disease.

Interdisciplinary Center on Aging: Brings together health providers, researchers and educators focused on older adults.

a onal Center for Soy ean Biotechnology: Provides genomic resources and bioengineering technologies to support the U.S. soybean industry.

Regional Bio Contain ent Library : Biosafety level-3 research facility, which includes an aerobiology suite for delivery of agents and therapeu�cs, as well as an animal lab that develops experimental models of infec�ous diseases.

Solu ons for a Be er Life

or ore infor a on contact:Robert DuncanVice Chancellor for ResearchUniversity of Missouri-ColumbiaPhone: 573-882-9500Email: [email protected]

Many of the world’s leading scien�sts in wheat, corn and soybean research work at MU. Le�, Melissa Mitchum, assistant professor of plant sciences, is working to stop damage of soybean cyst nematodes, a pest that can cause millions of dollars of damage.


Missouri S&T

MU

UMSL


From basic science to clinical research. From bioengineering to technology transfer. UMKC scholars are at the forefront of some of today’s most important research.

Interdisciplinary partnerships and intercollegiate collaborations create the foundation for addressing today’s health concerns. The Center of Excellence in the Study of Dental and Musculoskeletal Tissues and the Vision Research Center are two examples of interdisciplinary research programs at UMKC.

The interdisciplinary Center of Excellence in the Study of Dental and Musculoskeletal Tissues includes investigators from the UMKC Schools of Dentistry, Medicine, Nursing, and Computing and Engineering. This powerful translational team integrates clinical and basic science to prevent and treat diseases of mineralized tissue, including teeth, cartilage, bone, and muscle. The center’s research focuses on mineralized tissue and its relation to obesity, cancer, osteoporosis, bone trauma, aging, metabolic bone disease and diseases of oral tissue.

Implications of this research can be applied to biomaterials and composite research, medical devices, diagnostics, and clinical imaging. These implications also may be expanded to veterinary practice and diagnostics and treatment of animal dental and bone disease.

The state-of-the-art Vision Research Center combines clinical and basic research related to the diagnosis and treatment of age-related macular degeneration, diabetic retinopathy, glaucoma and other ocular diseases. This center positions Kansas City to become a national center for eye research, where these ocular diseases and others will be studied by some of the top researchers in the country. The results will then be seamlessly transferred into practical use with patients.

The Vision Research Cemter represents a synergistic collaboration between the UMKC Schools of Medicine and Pharmacy, Truman Medical Center, as well as other disciplines and schools interested in eye diseases.

Please join us at the 2010 Missouri Regional Life Sciences Summit in Kansas City to learn more about the research being conducted at these two centers, as well as other important research programs at UMKC.

or or i or o oLynda F. BonewaldInterim Vice Chancellor for ResearchUniversity of Missouri-Kansas CityPhone:816-235-1520 Email: [email protected]

UMKC

UMKC has seven different schools with ongoing research in health and life sciences. It is one of fewer than 30 universi�es in the na�on to have medicine, den�stry, nursing and pharmacy educa�on programs centrally located on one campus.

Changqi Xu, postdoctoral fellow, Department of Oral Biology


Looking forwardAmong the many other innova�ve life sciences research projects under way at Missouri S&T are:

• New image-processing techniques to diagnose skin cancer

• Early cancer screening using urinary pteridines as biomarkers

• The development of self-calibra�ng glucose sensors to help those living with diabetes be�er monitor blood sugar levels

• The study of an�oxidants for trea�ng lead poisoning

• The development of “biologically inspired” neural networks to be�er manage future “smart” power grids

UMKC

MU

UMSL


Delbert Day says it’s like seeding a fishing environment by throwing an old Christmas tree into the water. The submerged tree provides good pockets of cover for all kinds of fish.

But this isn’t really a discussion about aquatic habitats. Day, a Curators’ Professor emeritus at Missouri University of Science and Technology, is explaining why human bone cells would want to colonize medical scaffolding made out of glass fibers.

“Nature abhors a void,” he says. “And the body likes certain kinds of glass.”

Over the past few decades, Day has developed a number of biomedical applications for glass, including the treatment of liver cancer with tiny, radioactive glass spheres, a process he developed with Gary J. Ehrhardt, a senior research scientist at the University of Missouri-Columbia Research Reactor. The beads are now marketed under the name TheraSphere. These days, Day is working with fellow Missouri S&T researchers to develop 3-D scaffolds made out of bioactive glasses. They plan to use the scaffolds for bone regeneration.

“Cells can get inside the scaffolding, grow, and develop in the pores,” Day says, “just like the fish colonize the Christmas tree.”

But while the tree never becomes one with the fish, the scaffolding eventually does become part of the bone.

Titanium rods are often used to repair badly damaged bones. But Day and his colleagues say the glass scaffolding is, mechanically, much closer to the composition of real bone. Compared to metal implants, which are smooth and rigid, the scaffolding is porous and downright hospitable.

“Over time, the scaffolding would become indistinguishable from bone,” says Roger Brown, a professor of biological sciences who is working on the project. “It becomes part of the bone structure.”

The Missouri S&T researchers have formed a partnership with researchers at the University of Missouri-Kansas City to form the Center for Bone and Tissue Repair and Regeneration. “We do the materials work here,” says center director Len Rahaman, a professor of materials science and engineering at Missouri S&T who is working with Day and Brown. “They do the clinical work at UMKC.”

Four bioactive glasses selected by the Missouri S&T researchers are being evaluated in Kansas City. Once the best glasses are identified, Rahaman will lead the effort to build new scaffolds in Rolla. Prototypes will then be placed in animals, and, if everything goes according to plan, the method will ultimately be tested in humans.

If the scaffolding works like they think it will, the Missouri S&T team will have played a big role in changing the way medical professionals treat bone trauma. But Day, Brown and Rahaman don’t want to stop there.

They hope to develop something that really speeds up the process of regeneration – something even better that could be quickly employed in emergency rooms and on the battlefield.

Wayne Huebner, chair of S&T’s materials science and engineering department, envisions a future where information on human bones is catalogued like fingerprints are today.

“In the future, humans may have a computer-aided design file of their entire skeleton made by magnetic resonance imaging,” Huebner says. “Then, if someone needed a new bone, a rapid-prototyping machine could make one out of the bioactive glass. A surgeon would simply install it and your body would do the rest, converting the glass into an entirely new bone.”

or or infor a on on aK. Krishnamurthy, Ph.D.Vice Provost for ResearchMissouri University of Science and TechnologyPhone: 573-341-4154Email: [email protected]

Missouri University of Science and Technology researchers (from le�) Roger Brown, Delbert Day and Len Rahaman are crea�ng glass scaffolding to rebuild bone �ssue through a joint effort with the University of Missouri-Kansas City.

This enlarged image shows how bone cell grows on glass scaffolding at the microscopic level.

Missouri S&T

Bioac�ve glass “sponge.”


UMKC

Missouri S&T

MU


The University of Missouri-St. Louis is a leader in life sciences research in St. Louis. Bringing together top researchers from around the globe, UMSL strives to take its ground-breaking ideas from the university to the marketplace. The institution is transforming Missouri into a knowledge-based economy dependent upon innovation and entrepreneurship.

As a public land-grant university located in Missouri’s most populous and economically important region, UMSL is St. Louis’ partner for progress - in life sciences and beyond.

The university’s researchers are creating real solutions to real problems. Just one example is Xuemin “Sam” Wang, the E. Desmond Lee Endowed Professor in Biology, who is conducting research to understand plant lipids/oils, the most energy-rich natural plant products that can have significant impact on food, health, renewable energy and sustainability. Other examples of ground-breaking research at UMSL include:

Antiviral drug to treat all clinically important forms of the Human Papillomavirus (HPV). This would be the first therapeutic agent, offering non-surgical treatment options for women affected by

the virus that can lead to cervical cancer.

Non-invasive blood glucose monitor. This monitor will make blood sugar level testing multiple times a day pain free and more palatable -- especially for children with diabetes.

Through brain research, a faster, more accurate method to diagnose mild traumatic brain injury.

Quantitative Three Dot (Q3D) test to help catch vision suppression earlier than current methods being used. That would lead to better treatment and decrease the negative impact of amblyopia, commonly referred to as “lazy eye.”

Technology that could create a faster and less expensive way to identify diseases like prostate cancer. With a new simplified immunoassay, an analytical method that detects antigens or biomarkers, UMSL researchers can measure specific antigen-antibody interactions that indicate disease.

A device to protect premature newborns from aluminum toxins. A small filter will remove aluminum from intravenous feeding solutions used for premature babies.

Michael Howe, senior research engineering technician in the College of Optometry; Carl Bassi, associate professor of optometry; and Wayne Garver, research scien st in the Department of Physics and Astronomy, demonstrate a device they created to measure light sensi vity in pa ents. There currently is no other device that does this.

or or i or o oNasser ArshadiVice Provost for ResearchUniversity of Missouri-St. LouisPhone: 314-516-5899Email: [email protected]

UMSL

Bethany Zolman, assistant professor of biology at UMSL, studies hormones that control plant growth and development. Her research may allow her to manipulate these pathways to increase roo ng and enhance plant growth. She received a $575,000 grant from the Na onal Science Founda on for this research.


St. Louis Community College (STLCC) has made a ma-jor investment to address the needs of the growing plant and life sciences industry within the St. Louis region and the state of Missouri. STLCC, in October, 2009 established its Center for Plant and Life Sciences inside the newly completed Bio-Research, Development and Growth Park (BRDG Park), leasing 10,500 sq. ft. of of-fice and laboratory space within a post-incubator facili-ty located on the campus of the Donald Danforth Plant Science Center. This new space allows for expansion of the College’s A.A.S. bio-technician training program and for collaboration between the program participants and post-incubator businesses occupying space within the BRDG Park. The overall impact of this partnership will be to expand the workforce of trained technicians by expanding the amount of laboratory teaching space available, while offering students a “real-world” work experience in an industrial setting, where students will be able to interact on a daily basis with scientists from other companies residing within BRDG Park. The building that STLCC has leased space is phase one of a three phase building project that will ultimately pro-vide the St. Louis region with 500,000 sq. ft. of much needed wet lab space for developing companies coming out of local business incubators and universities. The opportunity of collaboration between the community college and these companies is seemingly unlimited.

The STLCC space within BRDG Park includes office space for the Center for Plant and Life Sciences and the teaching faculty, a 30 person teaching classroom,

bio-manufacturing lab, tissue culture lab, molecular bi-ology lab and support space, which includes a centrally located instrumentation lab where major equipment can be accessed without disturbing classes that may be taking place in the various labs. This is a flexible space that can be utilized for both scheduled classes and for specialized training programs to address needs within the plant and life sciences industry.

Through a National Science Foundation (NSF) grant, awarded in 2008, STLCC has also established, within the STLCC space, a Contract Research Organization (CRO), allowing the A.A.S. students training there to provide a much needed service to small, growing com-panies within the St. Louis region, by doing contract work on projects that companies just don’t have the equipment or time to do. Work of the students would be directed and overseen by a Senior Research Scien-tist/CRO Coordinator which will be initially funded through this grant. The CRO will provide a process for local biotechnology companies to contract with STLCC for assistance in completing projects that re-quire equipment that they do not have access to, but are available at the BRDG Park facility. Through the CRO, the college will provide a service to the local industry, while building lasting relationships with start-up com-panies that will become employers of graduates from the technician program in the future. These projects will be completed utilizing bench technicians trained in the technician programs within the umbrella of the STLCC Center for Plant and Life Sciences, which in-

clude Biotechnology, Chemical Technology, Clinical Laboratory Technology and Horticulture. The NSF grant provides funds for internships for students from the plant and life science related technicians programs at STLCC to perform the contract work, while pursu-ing their degree on a full-time basis.

The new space at BRDG Park also allows STLCC’s Center for Plant and Life Sciences to expand training for area teachers and students with an interest in science. Funding for this project has been procured through NSF grant sources and will provide for two, week- long camps each summer during the three year granting period, one week for 20 middle school students and one week for 20 high school students. STLCC also, through NSF funding, offers week long training ses-sions for 15 area science teachers interested in learning high-tech biotechnology techniques and bring those successfully into their classrooms. This course, taught by STLCC faculty and industry specialists will give the teachers a working understanding of the major proce-dures used within the plant and life science industry and how to best incorporate them into their existing science curriculum. The teachers are also be given the opportunity to visit some of the major employers for technicians within the region to gain an understand-ing for the job opportunities available for students who complete the A.A.S. degree at St. Louis Community College and how the students can then go on to ad-vanced degree programs should they wish to do so.

St. Louis Community College Moves its Center forPlant and Life Sciences to BRDG Park

U.S. Senator Christopher “Kit” Bond (R) Missouri visits with students from the Biotechnology program from the STLCC Florissant Valley campus, as they train in the new Center for Plant and Life Sciences facility established at BRDG Park, on the Donald Danforth Plant Science Center campus. Senator Bond recently spent an hour touring the facility and talking with current students of the biotechnology program, as well as some who have graduated and are working in the industry.

www.stlcc.edu


FLORISSANT VALLEY • FOREST PARK • MERAMEC • WILDWOOD

The Center of Excellence provides existing-technologies certification and training for the area’s plant-and life-sciences work force.

A community partner in thedevelopment of emerging-technologies programming to support the regional plant- andlife-sciences industry.

PROGRAMS Biotechnology Chemical Technology Clinical Laboratory Technology Horticulture

SPECIALIZED COURSEWORK Bioinformatics Bioprocessing

The Center for Plant and Life Sciencesa t S T. L O U I S C O M M U N I T Y C O L L E G E

For more information about theCenter for Plant and Life Sciences,visit www.stlcc.edu or contactDr. Richard Norris at 314-513-4951or at [email protected].


GENETIC CORRELATION PATENTS FACE COURT CHALLENGE

Vince Keil, Tim McBride, and Paul Fleischut are patent attorneys at Senniger Powers LLP, which in 2009 celebrated its 90th year practicing exclusively intellectual property law.

By Vincent M. KeilTimothy B. McBridePaul Fleischut(l to r)

The American patent system encourages innovation through a pivotal balancing of public and private in-terests. The exclusive right of patent protection is only available for an invention if it is an advancement of the “useful arts,” i.e., it must have utility, and it must be new and non-obvious.

The American Civil Liberties Union sued Myriad Ge-netics in 2009 challenging the patentability of claims involving the correlation of genetic mutations to pre-disposition to breast cancer, and claims covering cer-tain BRCA genes themselves, in isolated and purified form. The US Patent Office, Myriad, and the University of Utah Research Foundation filed motions to dismiss the lawsuit for lack of standing, lack of subject matter jurisdiction, and as barred by the sovereign immunity. The US District Court for the Southern District of New York denied these motions in November 2009, so the suit will go forward.

Patent Claims Covering Using Genes for Diagnosis and Prediction

The ACLU has challenged the patentability of Myriad’s patent claim in U.S. Patent No. 6,033,857 which covers comparing a sequence of a patient’s BRCA2 gene with a sequence of a normal BRCA2 gene and making an assessment of predisposition to breast cancer based on that comparison.

Under the Federal Circuit’s recent decision in In Re Bil-ski, a process is patentable only if it is tied to a particu-lar machine or apparatus, or it physically transforms an article into a different state or thing (In re Bilski, 545 F.3d 943, 954, Fed. Cir. 2008). Myriad’s cancer pre-disposition assessment process is not limited to a par-ticular machine, so to be patentable it must qualify as transformative for patentability under Bilski. The Patent Office has interpreted the Bilski test as requiring a physi-cal transformation. So to the extent Myriad’s process involves only a transformation from information about a gene’s sequence into information about predisposition

to breast cancer, the claims may be unpatentable under current Federal Circuit authority.

The ACLU also asserts that certain of Myriad’s method claims cover “abstract ideas or basic human knowledge and/or thought,” and therefore violate the First Amend-ment. The logic would be that a patent claim cannot be valid if it were infringed by viewing the results of a ge-netic test and reaching a conclusion in one’s head about a predisposition to breast cancer.

Patent Claims Covering Isolated and Purified Gene

The US Supreme Court held in Diamond v. Chakrabarty (1980) that a genetically-engineered bacterium capable of breaking down multiple components of crude oil, a property that no known naturally-occurring bacteria possessed, was patentable. Finding that Congress in-tended the statute to cover “anything under the sun that is made by man,” the Court concluded that the bacterium was a “nonnaturally occurring manufacture or composi-tion of matter.” So under Chakrabarty, a naturally oc-curring article, such as a bacterium, may be patentable if the end product has been sufficiently altered by the inventors. Similarly, naturally occurring genes are pat-entable when they are purified into isolated sequences of nucleotides.

The ACLU’s complaint takes issue with this proposi-tion, asserting that an isolated and purified human gene possesses no patentable distinction over a gene naturally occurring in the human body. The encoded information is identical whether the gene remains in vivo or has been isolated and purified ex vivo.

The Patent Bargain: Balancing of Interests

By claiming an “isolated and purified” product of nature, does one essentially side-step the long-standing prohi-bition on patenting a product of nature, since any com-mercial use of a natural product would likely begin with

its isolation and removal from the environment? Yes, according to the ACLU. It argues that the Myriad pat-ents constitute overprotection, and hinder the progress of further research more than promote it.

But in exchange for disclosing discovery of a correlation between a particular gene and a cancer, aren’t the inven-tors entitled to a limited monopoly over their invention? In the case of gene patents, and the potential benefits to human health, the ACLU asserts this bargain too heav-ily favors the patent holder.

The patent system requires an inventor to disclose how the invention was made and how it can be used, which information other scientists can use in their own re-search. However, in the case of a gene patent, the pat-ented genetic sequence is the useful information. The claims may dominate and foreclose further research and improvements, because the patented genetic sequence is identical to those actually present in nature. On the other hand, the information required to be disclosed by the patentee can be used by subsequent scientists to discover other genetic markers that correlate with an in-creased risk of developing the same condition. Without the Myriad patents — i.e., if the patented correlation were immediately dedicated to the public — isn’t there less economic incentive to search beyond the current, and perhaps inferior, knowledge of genetic markers for the particular cancer?

We all lose if links between genetic mutations and can-cer are not discovered. Patent protection is necessary to encourage innovation in medical research into such links. Research requires a substantial infusion of capital, at the risk of never paying off. By removing the ability to patent “isolated and purified” genes, we risk under-protecting investments in genetic research. The court considering ACLU’s claims must find a proper balance between preserving financial incentive for medical re-search, and granting patent rights over naturally occur-ring matter.


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The United Nations projects that the world’s population will exceed nine billion people by 2050. To feed this predicted

population, the U.N. has called for a 100 percent increase in food production using virtually the same land as today. To meet this goal

will require efficiency and sustainability on the part of the food production industry.

Efficiency and sustainability are at the core of the Novus vision to “help feed the world affordable, wholesome food and improve the quality of

life.” At the forefront of attaining sustainability and efficiency in the animal production industry, Novus International constantly researches

innovative new products and programs with real world applications.

By providing products and programs that address animal health and nutrition issues such as feed conversion, nitrogen pollution and amino acid supplementation, Novus helps producers realize lower production

costs, increased efficiency and a reduction in product losses. These solutions are a direct result of tireless research and experimentation that

contribute to addressing the global necessity to produce food more efficiently and with dramatically less impact on the environment.

Through the sharing of knowledge and addressing producers’ concerns, Novus is a true partner to the animal agriculture industry. Today, over 2,500 producer, feed mill, nutritionist and veterinarian clients in more

than 90 countries trust the Novus product and program family to be an integral part of their daily animal agricultural operations.

Novus feels a responsibility to discover practices and share the knowl-edge of these practices to support access to nutritious, affordable food. Through partnerships, Novus is engaged in knowledge transfer to help scientists and producers around the world address local issues from a

global perspective. Researchers and producers in countries such as China, Thailand, Korea, Vietnam, India and Brazil are offered this knowl-

edge to help address their bottom line. Leading universities worldwide work with Novus through contract and dedicated agreements to carry out

scientific trials in the areas of pathology, immunology, physiology and nutrition. In order to prove product efficacy in large scale operations,

Novus has agreements with commercial swine, broiler and dairy produc-ers. Together, this developed global network expands to help

ensure that Novus products and programs address animal nutritionand the environment.

Food should be a given, a right of the people, not an option. As our planet's population continues to rise, the ability to maintain efficiency and

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world with a profitable business model that has a minimal impact on the environment, Novus is helping the food production industry

scale to meet demand.

For more information on Novus International, please visit www.novusint.com or join our social media groups

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® is a trademark of Novus International, Inc. and is registered in the United States and other countries.

©2010 Novus International, Inc. All rights reserved.1753

STRIVING FOR EFFICIENCY AND SUSTAINABILITY

28 | missouri regionAl life sCienCes summit An Advertising supplement to the KAnsAs City And st. louis Business JournAls12 | MISSOURI REGIONAL LIFE SCIENCES SUMMIT AN ADVERTISING SUPPLEMENT TO THE KANSAS CITY AND ST. LOUIS BUSINESS JOURNALS

C erner’s research solutions provide academic sites with the infrastructure required to meet the clinical and translational objectives of research: collaboration within and between sites; patient-centric coordination of care for both healthcare

and research purposes; and the rapid availability of new evi-dence at the point of care so new findings can immediately be translated into improved patient outcomes.

Cerner helps academic medical

centers, like the University of Missouri, which is working

with Cerner to become a national

model of healthcare excellence, increase efficiencies, acceler-

ate study start-up and reduce costs through all

stages of clinical research. Our research solutions and services

facilitate connections between all par-ties involved in research—internally across

the organization and externally with other sites and sponsors, and with study participants as well. Cerner also integrates clinical care and clinical research processes, workflows and data that have historically been disparate and disconnected.

The Cerner Research Network (CRN) and the Discovere™ Web-based platform facilitate research activities within a clinical site, between collaborating sites, and between re-search sites and sponsors.

Researchers at academic centers often sponsor, design, and initiate their own studies that require collection of data from within their organization and from collaborating sites. The CRN enables this collaboration by helping the academic sponsor identify other clinical sites with patient populations matching the study criteria. An academic center, serving as a research sponsor, can use Cerner’s Discovere Web-based platform to easily collect research data from these collaborat-ing sites.

Likewise, when academic centers participate as a collabo-rator in research efforts initiated by other academic centers or research sponsors, CRN helps them identify studies best suited to their patient population or those of other sites within their region.

By connecting the academic center to other sites within the region, which may include rural hospitals and clinics that typically have limited research opportunities, CRN makes research efforts more successful by bringing multiple organi-zations together, fostering collaboration.

CRN connects academic centers to many types of quali-fied research opportunities that may include:

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Cerner research solutions at a glance:

Cerner Research NetworkThe CRN was designed to ensure patient privacy and

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DiscovereCerner’s Web-based Discovere research platform inte-

grates clinical research with clinical care. Academic re-search centers use Discovere to support and manage clinical research across their organization and with collaborating sites. Discovere uses integrated data capture (IDC) to elec-tronically transcribe information from the electronic health record (EHR). Discovere is also interoperable with multiple EHRs. The Discovere Study Management solution supports integrated workflows for investigators, research coordina-tors, data managers and study participants. The Biobanking solution allows sites to manage and track access to biological specimens and supports the banking of biological samples ranging from DNA to solid tissues.

PowerTrialsAcademic sites also use Cerner solutions to integrate

research processes into the workflow of their clinicians who use our electronic medical record. The PowerTrials® solution allows sites to identify patients that may be candidates for research and informs clinicians if their patients are partici-pating in any studies. This provides a more complete picture of a patient’s medical activities/history and enhances patient safety. Benefits include increased clinical trial participa-tion by clinicians and patients and streamlined clinical trial screening, enrollment, documentation and data capture.

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An Advertising supplement to the KAnsAs City And st. louis Business JournAls missouri regionAl life sCienCes summit | 29AN ADVERTISING SUPPLEMENT TO THE KANSAS CITY AND ST. LOUIS BUSINESS JOURNALS MISSOURI REGIONAL LIFE SCIENCES SUMMIT | 13


From its inception in 1968, ABC Labo-ratories has been dedicated to solv-ing scientific problems and providing

expert analytical and organic chemistry and biology services to the life sciences indus-tries. Founded by Charles Gehrke, Ph.D., a prominent researcher of biochemistry at the University of Missouri, the company is among the first true examples of “technology transfer” from the state’s university system.

ABC Laboratories is located in the heart of Missouri’s life sciences corridor, midway between Kansas City and St. Louis. We operate out of three locations: our original campus about five miles east of Columbia, and our 90,000 square-foot pharmaceutical development facility at University of Mis-souri’s Discovery Ridge Research Park that opened in late 2008. ABC acquired its third location, Morse Laboratories in Sacramento, California, in 2009, and operates it as a wholly owned subsidiary. We presently employ 330 scientists and support personnel, and gener-ated $35 million in revenue in 2009, most of it from out-of-state sources.

What We DoABC Laboratories has evolved over its 40-plus years to meet the needs of the companies it serves, applying its historical strengths in regulatory compliance and laboratory analy-sis. Today, our business is commonly known in our industries as a contract research orga-nization (CRO). We provide a broad array of outsourced development services to the pharmaceutical, animal health, agriculture and chemical industries—supplying the sci-entific data necessary to demonstrate safety

and efficacy of products prior to commercial-ization. This data becomes part of submis-sions to the FDA, EPA and other regulatory bodies charged with approving products for human, animal and environmental use.

Outsourcing is playing an ever-increasing role in the development of most successfully commercialized products. As the strategic importance of outsourcing has grown, our clients have become challenged to re-eval-uate, re-think and refine their relationships with contract service providers. The industry continues to experiment with a variety of approaches—ranging from procurement and “preferred provider” models to true long-term alliances. And they are looking to contract research organizations for answers.

How ABC is DifferentABC Laboratories differentiates itself as a development partner not only on its tech-nical expertise, but in the way it conducts business. As our clients endeavor to develop more effective solutions to global human and animal health, food supply and environmen-tal issues, we strive to apply the very best, current scientific practice, and to continually raise the bar on operational excellence.

Over the past several years, ABC has made significant investments to re-engineer busi-ness processes and develop systems to opti-mize the efficiency, improve communication across the organization and enhance cus-tomer service. The result is more compressed time-to-market, better cost management, and mutually rewarding, long-term client relationships.

Learn More.Visit www.abclabs.com today.

Analytical Bio-Chemistry (ABC) Laboratories

Services for Pharmaceuticaland Animal Health IndustriesABC supports the development of both chemically and biologically based pharma-ceuticals and animal health products with a broad array of development services:

support early development, preclinical and clinical studies, with niche exper-tise in CGMP radiolabeling synthesis, a service which is in high demand by pharmaceutical companies looking to speed time-to-market.

-opment services, including expert methods development and valida-tion, metabolism, pharmacokinetic analysis and bioanalytical testing services performed under GLP (good laboratory practice) guidelines.

-trols (CMC) services, including meth-ods development and validation, trace analysis and structural chemistry, and stability and release testing of Active Pharmaceutical Ingredients (APIs), clinical trial materials, raw materials and container/closure components and manufactured finished products. These services require strict adher-ence to current Good Manufacturing Practice (GMP) guidelines.

Assessment studies required by U.S. and European regulators to under-stand the ecotoxicological effects of drugs in the environment.

Services for Crop Protectionand Other Chemical Industries

ABC plays a leading role in the global imperative to produce safer, more effec-tive crop protection and other chemi-cals. We offer the full range of field and laboratory services needed to support the development and global registration of chemical, biochemical, microbial, and biotechnology products. Through techni-cal expertise and a full range of testing services, we help our clients meet increas-ingly stringent governmental regulations, including those of the REACH program in Europe and the Endocrine Disruptor Screening Program in the United States.


CHEMICAL SERVICES PHARMACEUTICAL SERVICES phone 573.777.60007200 E. ABC Lane 4780 Discovery Drive fax 573.777.6033

Columbia, Missouri 65202 Columbia, Missouri 65201 www.abclabs.com

It isn’t just superior science.It’s how we run our business.

When choosing a Contract Research Organization, it is well understood that technically sound, regulatory-compliant science is a must-have. But at Analytical Bio-Chemistry Laboratories, we know that it’s the business side—the processes, the systems, the communication—that make or break a CRO-sponsor relationship.

What does your CRO do to ensure on-time delivery? Manage quality? Reduce risk? Communi-cate effectively and transparently? How can the right development partner make your job easier? Let ABC Laboratories show you! Call us or visit www.abclabs.com today.

Analytical Bio-Chemistry Laboratories, Inc.

Why Choose ABC Laboratories?

Chemical ServicesResidue ChemistryAnalytical ChemistryPlant MetabolismAnimal MetabolismEnvironmental FateEcotoxicology

Pharmaceutical ServicesRecently Expanded! Biotech Services Pre-Clinical DevelopmentClinical DevelopmentChemistry, Manufacturing & Controls Custom Synthesis & RadiolabelingEnvironmental Assessments

32 | missouri regionAl life sCienCes summit An Advertising supplement to the KAnsAs City And st. louis Business JournAls12 | missouri regional life sciences summit an advertising supplement to the Kansas city and st. louis Business Journals

by Ramin R. Cherafat

Laboratories of every type—academic, research, and production—continue to be designed and con-structed even within the current economic recession. As the biotechnology industry increasingly grows, the timely and efficient creation of these facilities has become crucial, so much so that architects, engineers, and construction managers must reexamine previously accepted project delivery methods.

The traditional design-bid-build approach, based on the owner, architect, and contrac-tor triad has demonstrated several limitations within the laboratory building type. These limitations generally center on cost control and schedule delays.

Both of these factors—cost and schedule—are so criti-cal that any project delivery approach that can lessen the

uncertainty associated with them will have a dra-matic decrease in risk to the owner. Delays and cost overruns in laboratory projects will negatively affect time to market in a production facility, for example, or impair the educational program and research mis-sion in an academic facility.

Recent experience in completing laboratory facili-ties has shown that early inclusion of a construction manager creates a material advantage to the overall project. The involvement of a construction profes-sional may take several forms depending upon the design and construction contracts appropriate to a particular owner; regardless of the contract form, collaboration with the construction manager will provide early and frequent cost and schedule data. Here is a look at several key issues of professional col-laboration and the construction manager’s contribu-tion to the project.

Designing to a BudgetThe construction manager should be involved at

the commencement of design. An initial “order of magnitude” cost estimate, based on the facility’s mis-sion and uses, square footage, types of laboratory and office spaces, design and size of major building sys-tems, is prepared at this stage. While this early cost estimate will include a contingency, it will serve to establish and validate the overall scope of the project. As design proceeds, the construction manager will continue to refine the cost estimate and simultane-ously develop the construction schedule and evaluate be quality of systems. This iterative approach allows the architect/construction manager team to constant-ly evaluate the value of each design decision and, in conjunction with the owner, adjust the design as needed or desired. Once construction documents are completed, the cost estimate, having been continu-ously developed, will be reasonably accurate and should have a contingency in the 3-5% range.

Modular Construction and LayoutModular construction and layout of the building

can realize significant cost savings. Mechanical, elec-

trical and plumbing (MEP) systems, which represent as much as 50% percent of the total construction cost, can benefit from modularization. Repetitive elements of the laboratory should be identified and placed to maximize efficiency and ease of construc-tion as much as possible. Multistory buildings can take advantage of stacking MEP systems, particularly those that will rarely require reconfiguration in the future. Long lead items, such as fume hoods and casework, can be designed and fabricated in advance to obtain cost advantages.

Retaining Future FlexibilityConcurrent with modular design is the need for

flexibility with future expansion or reconfiguration of laboratory space.

The construction manager can evaluate the building shell and MEP systems with regard to cost-effective future expansion. For example, major components such as chillers, air-handling units, the mechanical distribution system, various lab utility systems and exhaust systems may be selected with a higher capacity to support future additions.

The additional capital investment in larger units often is less than the future cost to replace these components when expansion of the lab creates increased loads.

In addition, the team can collaborate on the de-sign of laboratory interiors to gain the most efficiency in the manufacture and installation of casework, the electrical system and lighting fixtures. The designa-tion of “flex zones,” or non-modular areas that can be reconfigured for new uses may be an attractive strategy.

Designed for Energy Efficiency and Sustainability

Today, many owners are also asking their project teams to incorporate energy efficient, sustainable, engineering and construction technologies into new lab facilities. These include energy-efficient HVAC and fume-hood systems, sustainable building prod-ucts, natural lighting and energy-conserving lighting controls, and overall building control systems.

Approximately 20 percent of all costs are hard construction costs, whereas approximately 80 percent is allocated to the costs for maintaining operation throughout the lifecycle of the facility. The construction manager can also provide the owner with an analysis of the life cycle costs of the building and assist in the selection of mechanical systems and equipment. Operating costs, primarily mechanical and electrical systems, can be many times the con-struction cost; collaborating with the design team, the construction manager can establish these costs and save the owner significant expenditures over the operating life of the facility.

Owners and project teams are also designing labo-ratory spaces that enable greater collaboration among scientists in a number of disciplines. For example, laboratories often include open spaces and movable casework to enable multi-disciplinary research and development teams to work more closely together.

These types of requirements can be incorporated more cost-effectively when the project team consid-ers them early in the design phase.

Ramin R. Cherafat is a Partner and Vice President of Opera-tions with McCownGordon Construction. A construction manager with an M.B.A. in Finance, Cherafat has exten-sive experience in construction management, design-build and general contracting for the bio-sciences field, including pharmaceutical firms and academic institutions. He can be reached at 816-877-0651 or [email protected].

Bringing Value to Projects Through Early Partnerships


Partnering for Innovation and Excellence. It’s what makes us McCownGordon.

At McCownGordon, we’re dedicated to building collaborative partnerships. From clients to architects and subcontractors to suppliers, we understand a true partnership comes from an integrated team established on day one. Without collaboration and innovative teamwork, the partnership simply won’t fit together. It requires commitment from all stakeholders to make a project a success.

McCownGordon is continually thinking of ways to build innovative practices into each biotechnology and higher

education project we work on. We’re finding better ways to conserve resources, decrease maintenance, improve efficiency and flexibility, and educate college campuses and lifescience clients on how to enhance everyday operations. We believe in fostering the growth and development of the industry while helping our clients build facilities that will provide their research and services needs long into the future. As a collaborative construction manager, we are achieving greater, innovative results – while building a partnership that seamlessly fits together.

When a partnership works, all the pieces have come together.


12 | missouri regional life sciences summit an advertising supplement to the Kansas city and st. louis Business Journals

On the horizonThe location decision is among

the most critical decision compa-nies will make. That’s why Liberty is the perfect location choice. Lib-erty’s focus in the next decade is on recruiting science and technol-ogy based sectors such as biosci-ence and advanced energy and the businesses that support them. Located along I-35, Liberty is so strategically located, you can get anywhere in the metro area in 30 minutes. KCI airport is an easy 15 mile-15 minute drive and I-29 and I-435 are within 5 miles and I-70 within 12 miles. With thousands of acres of developable land and excellent multi-modal accessibil-ity, Liberty is an ideal choice for innovative and growth oriented businesses.

Optimum location in the KC metro area

Combine the commitment to develop a science and technology business park with:

• A prime location along the Missouri/Kansas life and ani-mal sciences corridor

• Excellent access to and vis-ibility from I-35 allowing easy driving distance to St. Louis, Topeka, Omaha, and Wichita.

• Proximity to five leading re-search universities nearby

• Innovative and aggressive incentive programs

• An abundance of quality employees and skilled work-force. The median age of 36.2 offers a high quality, young and talented workforce.

• Reliable and affordable utility services

Liberty has targeted develop-ment sites including those at major intersections of I-35 and Highway 291, I-35 and Highway 69, I-35 and Highway 152 and greenfield areas along South Liberty Parkway – the thoroughfare that connects I-35 and Highway 291 along the south side of Liberty.

Targeted development areas in-clude the Heartland Meadows Busi-ness Park and sites along the South Liberty Parkway. Many land sites

are considered greenfield development, requiring no demolition, relocation or environment clean-up. Kansas City icon - Hallmark Cards, certainly knows access is critical and, consequently, chose Liberty for its 1.75 million square foot national distribution center.

Skilled Workforce Employment costs are among the largest

costs of businesses’ operations. In Liberty, the workforce is one of the community’s great-

est assets. Employers, both large and small, regularly rank Liberty’s workforce higher than regional and national averages for availability, quality, stability and productivity. A Liberty location makes excellent business sense, ac-cording to John Tankesley, Plant Manager for Piston Automotive,

“Because of Liberty’s thriving workforce, strong work ethic, support for small business and favorable work environment, it was an ideal loca-tion for us to start our operation and grow our business.”

Financial IncentivesCompanies enjoy a business friendly operat-

ing environment. Companies that are looking to expand or locate in the Liberty area have State of Missouri incentives available as well as aggressive local incentives. For example, the City of Liberty expanded their tax abatement programs that can provide 75-90 percent property tax abatement for new science and technology businesses.

More than LocationLiberty offers more than just location, acces-

sibility and incentives. Businesses and residents alike choose Liberty because of its quality of life that’s built around a rich and vibrant history, stellar primary and secondary, education and top-notch health care services.

Liberty Public School District, a partner in our science and technology efforts, is ranked in the top 10 nationally in pre-engineering by Project Lead the Way. With students consistently scor-ing above state and national norms on standard-ized tests and ACT scores that rank it among the area’s best, it is no surprise that the school district has been named a “High Performing School District” by the State of Missouri for seven consecutive years.

Liberty also is home to William Jewell College (WJC), which is consistently ranked as one of the top liberal arts colleges in the nation. U.S. News & World Report included William Jewell among the top 186 national liberal arts colleges in its 2009 edition of “America’s Best Colleges.” The Princeton Review named WJC as one of “The Best 371 Colleges” in its 2010 edition. Only about 15% of the four-year colleges in the U.S. appear in the student survey-based rankings.

The 250-bed Liberty Hospital, which is fully accredited by the Joint Commission, offers compassionate, exceptional care using the latest technology and a full range of services. The hospi-tal’s oncology program has received approval with commendation from the Commission on Cancer of the American College of Surgeons. The hospi-tal recently opened the first phase of its Liberty Regional Heart & Vascular Center and its Cardiac Rehabilitation program has been certified by the American Association of Cardiovascular and Pul-monary Rehabilitation.

With access to a skilled worforce, highly accessible location and superior quality of life, employers, large and small, have flourished in Liberty. The area abounds with entrepreneurial activity and small business owners as well as em-ployers such as Hallmark and R R Donnelly who have enjoyed a long-term presence here. With new financial incentives and available ground for development, science and technology start-ups and businesses will find that this area is the opti-mal choice to build and expand.

Liberty: The ideal choice for innovative and growth-oriented businesses

816.883.2503 www.thinklibertymo.com

An Advertising supplement to the KAnsAs City And st. louis Business JournAls missouri regionAl life sCienCes summit | 35an advertising supplement to the Kansas city and st. louis Business Journals missouri regional life sciences summit | 13

For more information contact Alicia Stephens, Executive Directorp: 816.883.2503 • www.thinklibertymo.com

You’re Free to Choose Location…immediate I-35 access

15 minutes from KCI & downtown KCavailable locations for every business type

I-35

I-29

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You’re free to innovate…

You’re Free to Choose Workforce…award-winning school district

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You’re Free to Choose Livability…one of money magazine’s best places to live

not “just another suburb”major hospital/prominent healthcare community


Transforming a discovery into a commercial product requires a team of professionals with the knowledge and experience to advance innovation, pro-tect intellectual property, attract capital, develop facilities or otherwise provide for the production and commercializa-tion of these opportunities, while avoiding unnecessary risks. With more than 750 attorneys and other professionals across the United States and in Europe, Son-

nenschein has represented many of the country’s leading universities in the de-velopment, protection and commercial-ization of their technologies. In addi-tion, government laboratories, emerging growth companies and Fortune 500 corporations in a broad array of indus-

tries turn to Sonnenschein to address their intellectual property, commercialization and production needs.

Sonnenschein has one of the most seasoned teams of Biosciences attorneys in the U.S. With broad experience handling highly com-plex matters, and demonstrated success in commercialization, intel-lectual property protection, litigation, counseling and venture capital transactions, Sonnenschein provides unparalleled service to our cli-ents, including universities and their medical center affiliates seeking to derive maximum benefit from the technologies they develop.

Selected areas in which we excel include:

Life Sciences ExperienceThe firm’s interdisciplinary approach to Biosciences and Life

Sciences matters exemplifies the depth and breadth of the firm’s capabilities. Attorneys in Sonnenschein’s Life Sciences & Technology Practice — with backgrounds in disciplines including genetics, bio-chemistry, microbiology, botany, plant pathology and cellular biology — understand the complex and unique legal issues associated with the biotechnology, genomics and proteomics sectors.

Sonnenschein’s approach to the Biosciences is unparalleled. Cli-ents turn to us because they know we have the built-in capacity to handle the entire spectrum of legal issues and challenges within the life sciences arena, from high-stakes patent litigation, to the lifeblood of any venture, raising capital, to addressing the most obscure legal and scientific issues in biotech, pharmaceuticals and agricultural biotechnology.

We have unmatched strength in the area of ag-biotech, a rapidly growing technology specialization spanning the animal health indus-try, plant genomics, plant pathology, bioenergy research & develop-ment, and commercialization in the cleantech sector. We represent food producers and distributors, protect patent portfolios, serve the varying demands of the pharmaceutical industry, advise biotech startups and ventures, and address all aspects of disputes resolution, litigation and issues management.

The firm’s Intellectual Property & Technology (IP&T) Practice in-cludes registered patent attorneys, former patent examiners and pro-fessional staff who are graduates of many of the top U.S. law schools, graduate schools, undergraduate programs, and bring their array of experience and capabilities in virtually all technical areas of IP law to bear on opportunities presented by firm clients. Among our inter-disciplinary team members are a large number of Ph.D.s, giving us the resources to support our clients in life sciences and related industries with an impressive arsenal of counseling, advice and client service.

Technology Transfer/Spin-OutsTechnology transfer has become an essential business develop-

ment strategy for research institutions and universities looking to capitalize on their intellectual property. Sonnenschein’s considerable experience representing universities, venture capital firms and cor-porate/strategic investors in technology transfer transactions allows us to structure transactions that benefit all parties.

Sonnenschein has played a leading role in technology commer-cialization efforts involving a broad spectrum of industry players. We excel at managing the relationships among parent companies, founders, management and venture communities across a wide range of areas, including corporate structuring, intellectual property, tax, accounting and strategic finance. Our vast experience in this respect

gives us in-depth knowledge of the anatomy of a university spin-out, including:

• Determining the status of an academic institution’s intellectual property

• Structuring alternatives and parent relationships• Building in management incentives

Patent Prosecution/TransactionsPatent lawyers at Sonnenschein provide comprehensive legal ser-

vices for the development, management and protection of clients’ pat-ent portfolios in the United States and abroad. In addition, our team includes patent scientists who bring to each matter a wealth of experi-ence in disciplines such as biology/life sciences, Healthcare IT, plant development, animal science, genetics, molecular biology, chemistry and we assist clients in the challenges presented by these technologies as they converge. Drawing on the cutting-edge scientific and techno-logical experience of these advisors, our patent attorneys are able to team with professionals in various other areas of the law to thoroughly assess legal and strategic patent matters with a national view of current trends and transactions.

Sonnenschein’s patent lawyers assist clients in managing their patent portfolios, offering research and development planning and counseling as well as creative advice on how best to leverage their in-tellectual property. Our team also provides carefully crafted opinions on the patentability of clients’ inventions and clients’ rights to use their technical innovations without charges of patent infringement.

Patent LitigationOur patent litigation attorneys have participated in many of the

most complex patent trials and proceedings around the country, often involving multiple patents and jurisdictions. As a result, they are able to quickly grasp the complex technological issues in a case and to respond with effective litigation strategies. The firm has ag-gressively represented large and small corporations, including both plaintiffs and defendants, in bet-the-company cases and cases that required quick and efficient resolution. Our attorneys have litigated cases in federal district courts across the country and before the U.S. International Trade Commission. Those representations have spanned many industries, including automotive, biotech, consumer electronics, hardware/networking, Internet, LCD panels and control-lers, pharmaceuticals, medical/surgical devices, semiconductors and more.

Laboratory, R&D and AdministrationSonnenschein offers our clients the full complement of skills nec-

essary to assist them in developing, permitting, financing and con-structing Bioscience projects from early concept through commercial operation. We have experience with a spectrum of Bioscience proj-ects, including Bioscience business parks, University Laboratories, Mixed Use LifeSciences Developments, R&D facilities, Bioscience, and a host of Bio-related or cleantech projects such as biomass, wind, solar, geothermal, and tidal projects, among others. We assist clients with navigating site selection, environmental due diligence, site acquisition or leasing, planning and zoning matters, financing, and state, local and federal permitting and compliance for facilities of all sizes, building types and uses. These efforts complement the exper-tise we offer in subdividing university owned property or facilities, on-site hosting of disparate uses, and identification of development opportunities for university property, existing or proposed facilities, and operations including development agreements with surrounding property owners, communities or other governmental or private enti-ties. We also assist with the variety of “green” technology retrofits, upgrades or enhancements that are being implemented in cities and states across the nation.

Our team is versed in assisting clients with the federal and state incentives, credits, loan guarantees and other benefits available to Life Sciences, Biotech R&D, or production projects, renewable energy projects, and the wide array of funding opportunities made available by the recently enacted American Recovery and Reinvest-ment Act or other state and local stimulus initiatives.

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Sonnenschein is among the leading national law firms and is renowned for providing cutting-edge emerging growth and Fortune 500 technology and life sciences companies, moving at breakneck speed in competitive markets, with nimble, fast-paced counsel at the convergence of finance, strategy, policy and law. Our clients in the life sciences industry include some of the nation’s largest pharmaceutical, biotech, medical devices companies, as well as leading life sciences-focused venture capital funds and investment banks, national laboratories, academic institutions, individual entrepreneurs and inventors.

For high potential entrepreneurs, our Sprout Incubation/Acceleration Initiative has been a growth catalyst for more than 100 successful start-ups from Silicon Valley to New York and around the globe. In fact, Sonnenschein’s Venture Technology Group has once again been ranked in the Top 10 nationally for venture capital deals, as reported by Dow Jones Private Equity Analyst.

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ARCO’s unique design/build approach for science and technology facilities can be described as customer centered solutions for development, design, and construction. We’re different in that our process focuses on listening, understanding, and then exceeding expectations. expectations. We consult and collaborate early in the planning and design process to insure our clients’ vision is realized with quality, schedule, and cost effective solutions. ARCO has consistently proven on life science, pharmaceutical, and analytical laboratory facilities that what we do and how we do it is not only unique, but extnot only unique, but extremely effective and valuable to the success and growth of our clients’ businesses.

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This facility is currently owned and operated by Millipore Corporation.

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Harness Dickey is among the nation’s leading intellectual property firms.

• Ranked among the nation’s top 5 patent filers*

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When you need a trusted business partner to protect your intellectual property and execute your legal strategies, choose Harness Dickey.

* As ranked by Intellectual Property Today in the March 2010 issue based on number of utility patents issued in 2009. The choice of a lawyer is an important decision and should not be based solely upon advertisements.

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At Harness Dickey, we understand the magnitude of the investments you have made. Along with rapid growth and expansion, the biotech and life sciences industries yield high risk and heightened competition. When it comes to highly technical research and development, security of intellectual property is crucial.

Harness Dickey draws upon the expertise of its team of more than 30 legal professionals who have the technical backgrounds necessary to not only understand the complexities of your work, but to fully partner with you in cultivating strategies to meet the many challenges you face. With backgrounds ranging from pharmaceuticals, medical devices and nutritional science to agriculture and bio-analytical arts, Harness Dickey’s attorney credentials include advanced degrees in biochemistry, microbiology, biomedical and chemical engineering, applied mechanics, physics, and other related disciplines. This depth and range of experience enables us to work efficiently and with great attention to each detail.

We handle all aspects of creating and managing intellectual property. Among our clients are the largest research-based pharmaceutical manufacturers, consumer product and medical device manufacturers, mid-size companies, start-ups and universities. Take confidence in the knowledge that you have the experience of one of the nation’s top patent filers, combined with first-hand knowledge of your industry.

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• EBI Medical, Inc.

• Elan Pharmaceuticals

• Gilead Sciences

• Hill’s Pet Nutrition, Inc.

• Medtronic, Inc.

• Michigan State University

• Monsanto Company

• National University of Singapore

• NCB Pharmaceuticals

• Ore Pharmaceuticals

• Sanofi - Aventis

• University of Michigan

• University of Stuttgart

• Zambon Group SpA

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HIGHER EDUCATIONApproximately $97 million of the Lottery’s FY10 profits fund 8 percent of the state’s annual contribution to Missouri’s four-year colleges’ general operating budgets, which fund salaries, equipment, library purchases and institution-based student financial aid. This includes $36.9 million for the four University of Missouri campuses and $7.5 million (5 percent of total state funding) for Community Colleges.

Since 1995, the Lottery has contributed more than $137 million to a wide variety of design, renovation, construction and improvement projects at numerous universities, colleges and schools across the state.

MIssOURI LOTTERy: IN BUsINEss fOR PUBLIC EDUCATIONMore than $3.5 billion for Missouri and public education!

The Missouri Lottery is in business to help fund Missouri public schools. The Lottery is nearly a $1 billion business, which expends only 3.8 percent to operate and returns an annual profit of 26.3 percent to public education. Since 1986, the Mis-souri Lottery has contributed more than $3.5 bil-lion to the state of Missouri and public education.

More than 95 cents of every dollar spent on the Lottery stays in Missouri. Annually, the Lottery: pays winners more than $600 million in prizes; awards more than $60 million to 5,000-plus small businesses who sell Lottery; and transfers more than $250 million to public education. The Missouri Legislature appropriates 100 percent

of Lottery profits annually to a variety of impor-tant elementary, secondary and higher education programs. The Lottery’s annual contribution of approximately $250 million comprises about 4 percent of the state’s funding for public educa-tion – an effort shared by local, state and federal governments.

ELEMENTARy AND sECONDARy EDUCATIONIn FY10, $108.9 million of Lottery profits are directed to the state’s public education Foundation Program, which helps pay for normal state aid distribution to schools, transportation, early childhood special education, career ladder, vocational education and early childhood development.

The remaining profits are spent on 14 different programs, including $21.8 million for the popular A+ Scholarship Program (86 percent of total program fund-ing). Students who graduate from a designated A+ school may qualify for state-paid assistance to attend any eligible public community college or technical school in the state. Some four-year public colleges and universities also participate in this program. Currently, there are 253 high schools that are designated A+ schools. Since 1997, 44,100 students have used at least one semester of A+ funding.

In FY10, $4.3 million of Missouri Lottery profits are appropriated for Performance-Based Assessment Program (MAP) testing for math and communications arts.

In FY10, $108.9 million of Lottery profits are appropriated to the state’s Foundation Program including transportation, early childhood special education, career ladder, vocational education and early childhood development.

Don Branson, A+ student, Missouri University of Science & Technol-ogy, Rolla.

Blanche M. Touhill Performing Arts Center, University of Missouri - St. Louis

Business & Technology College, Metropolitan Community College, Kansas City

Meyer Library, Missouri State University, Springfield


missouri lottery Commissioners

Kevin C. Roberts, Chair Breeze, Roberts,

Ponder-Bates, Wooten & Zimmer, LLC

Gina HoaglandCollaborative

Strategies, Inc.

Jacque M. Land Platinum Group, Inc.

Stephen H. Snead Wallace, Saunders, Austin,

Brown, EnochsAttorneys at Law

Pamela S. Wright Law Office of

Pamela Wright, LLC

May Scheve Reardon Lottery Executive Director

©2010 Missouri Lottery Commission

The Missouri Lottery is proud of the part it plays in helping our state’sfuture workers. The Lottery contributed nearly $260 million last year to Missouri public education programs and services. And that’s only the latest installment in ourcommitment to education- a sustaining commitment that has provided more than$3.5 billion to the state over the past 24 years.

A list of current Missouri education programs and services that receive Lottery fundsand an archive of past Lottery funds recipients are available on the Lottery’sWeb site, www.molottery.com

We’re Helping Put Missouri’sFuture Workforce To Work Today


By Brien Starner, PresidentBlue Springs

Economic Development Corporation

Over the past 4 plus years the Blue Springs com-munity has had the unique opportunity to witness and learn first-hand about growth and develop-ment drivers and opportunities that are shaping the community and the region’s economic environment and future. Blue Springs, with a population nearing 57,000 and an annual growth rate of 2%, is poised to position itself in the Kansas City region and within the global economy, particularly in light of the recent favorable announcements from the University of Mis-souri (MU) and their future plans for Blue Springs and the Missouri Innovation Park.

Growth and prosperity operate on a continuum which both ebbs and flows through communities, states and countries. The jarring economic transition we are experiencing today makes understanding each community’s place in the global marketplace more important than ever. By examining local and regional economic advantages, both local and regional assets can be strategically leveraged to a competitive advan-tage amongst global peers.

Competition is healthy for the economy, and its highest form is found when a concentration of a region’s wealth, assets and knowledge combine through groupings of business and industry clusters, as in examples like: IT and Silicon Valley; Bio-Med and San Diego; or Financial Services and New York, London or Tokyo. Clusters are not static but con-stantly are changing and only remain viable if they are dynamic, which historically is driven through both public and private research linked to a knowledge-based workforce in-turn supported through all levels of K-12 and higher education and workforce training.

It is reasonable to agree that when concentrations of similar companies and their customer and supplier

chains seek to build competitive advantage by linking value-added production, pricing, access to research and development, and integration of their knowledge-based workers, the results are successful industry clusters. These clusters possess, and will produce without fail, capital attraction, new business start-ups, co-location of high-growth companies linked to the regional industry clusters, and concentrations of highly produc-tive workers, knowledge-based jobs, and research and investment linkages tied to the region’s clus-ters.

Over the past three years leaders from the Blue Springs City Coun-cil, the Blue Springs EDC and Blue Springs Growth Initiatives have held extensive conversations with MU to attract the university to Blue Springs as the anchor tenant of the Missouri Innovation Park (MIP). The Blue Springs Growth Initia-tives, with MU’s input, is develop-ing a land use plan and master plan, identifying development opportu-nities, and crafting design guide-lines. The “Mizzou Center,” the first building planned for the Park, would offer close proximity to high-tech, life sciences businesses,

creating a unique opportunity for these businesses and MU faculty and resources to work side-by-side in a collaborative and synergistic approach.

MU plans to create a significant presence in Blue Springs by leasing office space in the very near future. MU intends to immediately lay the foundation for building corporate, civic, research and alumni out-reach and collaboration that links MU more directly to the region’s 2.4 million residents and 20,000 plus companies, particularly the linkages to animal health and nutrition and sustainable energy. The plans to engage area utilities, agriculture, research facili-ties, engineering expertise, and finally the region’s historic connection to agriculture and valued added food production focus are at the forefront of global demand for our region’s products which will increase over time. And, these plans strongly align with MU’s strategic goals in such areas as: Translational Medi-cine/Animal Health, Sustainable Energy, and Food For the Future.

MU’s interest in Blue Springs allows the com-munity to integrate competitive advantages that start with the State of Missouri, extend to MU, and link our region to the global market-place. This collabora-tive goal is to create high-wage paying 21st century knowledge-based jobs that create value-linkages to higher education, which in turn support and re-inforce area employers and their ability to prosper in the global marketplace in the years and decades ahead.

More information about the City of Blue Springs can be found at: www.ThinkBlueSprings.com. In-formation about the Missouri Innovation Park can be found at: www.MissouriInnovationPark.com.

Brien Starner is the President of the Blue Springs Economic Development Corporation, 1600 NE Coronado Drive, Blue

Springs, MO 64015, (816) 228-0208

Missouri Innovation Park = Innovation and Collaboration in the 21st Century

Proposed land use concept, located at Adams Dairy Parkway and R.D. Mize Road


Where innovationmeets opportunity!

• Located in the KC Animal Health Corridor, the largestindustry cluster concentration of animal health and

nutrition science interests in the world

• Cutting edge corridor for scientifi c and technology innovation

• Unique and focused business clusters supported throughpublic/private collaboration

• University of Missouri, the proposed anchor tenant, will house research, continuing education and community outreach activities

focused on scientifi c and technical innovation

MissouriInnovationPark.com816.228.0208


Washburn University:Educating the next generation of scientists, health care professionals, technicians and researchers for bioscience professions.

1 7 0 0 S W C o l l e g e Av e . | To p e k a , K S 6 6 6 2 1 | ( 7 8 5 ) 6 7 0 - 1 0 1 0 | www.wa shbur n . edu

Chemistryn One hundred percent acceptance of baccalaureate students in medical, dental and graduate

programs in the past seven years.n Degrees available in biochemistry, chemical forensic science and chemistry.n Undergraduate research opportunities in analytical, inorganic, organic, physical,

forensic and biochemistry.n Grants/stipends provided for undergraduate biomedical research, as part of the Kansas IDeA

Network of Biomedical Research Excellence sponsored by National Institutes of Health.

Biologyn Since 1996, 84 percent of pre-medical students who applied have been accepted to medical

schools, including Harvard Medical School.n Biology department graduates consistently score above the national average in the Major

Fields Test in Biology, taken each year by graduating seniors.n A WU biology degree effectively prepares graduates to directly enter the work force or to

pursue advanced degrees in medical, dental, optometry, pharmacy, veterinary medicine and graduate school (M.S. & Ph.D. degrees).

n The biology department supports other disciplines by teaching courses required for pre-nursing and pre-allied health programs.

School of Nursingn More than 2,500 professional nurses have graduated from the School of Nursing since its

inception in 1974.n The Master of Science in Nursing (MSN) program prepares students as advanced practice

nurses as either nurse practitioners or clinical nurse leaders.n Both the bachelor and master’s programs in the School of Nursing are approved by Kansas

State Board of Nursing and The Commission on Collegiate Nursing Education.

Allied Healthn Twenty percent of Washburn’s allied health graduates go on to graduate school.n The credentialing examination passing rates of allied health graduates exceeds the

national/state average for each discipline.n Meeting the needs of the community by working with St. Francis Health Center and

Stormont Vail HealthCare and other health care organizations in providing new health care programs to help fulfill current and future job openings.

To learn more about Washburn University, visit us online at www.washburn.edu.



College of Agriculture, Food and Natural ResourcesUniversity of Missouri

cafnr.missouri.edu

Less Food, More Profit. Feed constitutes 60% of cattle ranchers’ production costs. Animal Sciences Researcher Jerry Taylor found the genetic reason why certain cows gain weight while eating less feed. He’s sharing this with Missouri breeders who are replacing their herds with the efficient varieties. Missouri is second in the nation in beef cows with more than 2 million cows on 68,000 farms.

Studying Droughts by Making Them. Droughts have a devastating effect on farms. In Missouri and the world, droughts are the leading cause of crop failure. Unpredictable droughts are hard to study unless you make your own, which is what CAFNR plant scientists are doing in four new rain shelters. These devices will allow the researchers to study ways to allow plants to remain productive during dry conditions.

Uranium Traps. Biochemist Judy Wall is using sulfate-reducing bacteria to clean up radioactive residue that has leeched into the soil from Cold War production factories.

How Much More? Forestry Researcher Francisco Aguilar is determining how much more consumers will pay for certified forest products — information that will help Missouri producers profitably go green.

A Big Advance for the Little Soybean. Soybeans are one of the most important crops for their protein and oil, representing a $30 billion industry in the U.S. CAFNR scientists have helped identify the 46,000 genes in the soybean genome, allowing researchers around the world to increase food yields, develop new products and improve existing ones.

Seeing Autism. 1.5 million kids have this brain development disorder and there are no objective clinical tests to diagnose it. Bio-engineering researchers recently developed a test using modified ophthalmology devices to measure the slower pupil responses kids with autism have to light flashes. Such a diagnostic method will identify autism sooner and better monitor treatment results.

Healthy Ice Cream? Food Scientist Ingolf Gruen is making the confection into a functional food, adding nutrients such as fiber, antioxidants and probiotics to premium ice cream.

The Right Animal for the Job. Lab mice are a poor source of stem cells for research. Pigs, with similar heart and lungs to people, are a better model. CAFNR scientists are capturing fibroblasts from pigs and making them think that they are stem cells, something that could lead to new therapies for human disease.

Learning About Coral Reefs by Saving Them. Thailand’s coral reefs are threat-ened by damage from tourism and pollution. Students donned wetsuits and oxygen tanks to help transplant healthy coral scrubs from a nursery to the damaged reefs.

Weather Forecast: August 10, 1861.Mike Madden, an atmospheric sciences sophomore, was curious — did an unexpected rain shower at the Wilson’s Creek Battle during the Civil War save Missouri for the Union? To find out, he became a weather detective to create a forecast 150 years back in time decades before there were US weather stations.

A Solution to Pollution. Each year, millions of tons of waste bottles, broken glassware and light bulbs foul landfills. Sam McKee, study-ing forestry, had an idea — grow tomatoes in the broken glass. His solution is less expensive than conventional hydroponic methods.

Chasing a Winter Phenomenon. Thundersnow is a rare event that can dump dangerous amounts of snow. Its trigger is little understood. Storm-chasing students use radar to find these rare clouds and release weather balloons into them every 90 minutes, giving meteorologists new data to improve forecasts.

World-Class TeachingAdvanced Research Shared Knowledge

Making anImpact...now

College ofAgriculture, Food andNaturalResources


next National Cancer Institute designation

in nationpharmacy residency program

#1 #2 in nationpharmacy research

KU CANCER CENTERcancer.kumc.edu

KU MEDICAL CENTER, KANSAS CITYkumc.edu

LAWRENCE CAMPUSku.edu/research

In the heart of the nation and the center of the bi-state life sciences corridor is the University of Kansas.

A national leader in cancer-drug research,

KU has a long record of research col-

laboration. We have attracted an honor

roll of researchers and scientists and have

invested nearly $200 million in bioscience

research and education infrastructure

in the past decade. Annually we spend

more than $300 million on research.

Next up: The goal of NCI designation to

bring the region access to the newest,

most promising cancer therapies and

laboratory discoveries.

LEARN MORE AT

A great place to be

Blake Peterson, KU distinguished professor of medicinal chemistry, with researcher Runzhi Wu.



Thirteen is turning out to be a lucky number for Kirk Schulz.

As Kansas State University’s 13th president, Schulz is getting the opportu-nity to lead the university in its role as a national leader in animal health and food safety research and making K-State the western anchor for the Kansas City Animal Health Corridor.

Leading a university to excellence in life sciences isn’t new to Schulz. Before he came to K-State, Schulz was vice president for research and economic development at Mississippi State Univer-sity, where he worked to bring research opportunities to that university.

Now, Schulz’s role as K-State’s presi-dent is to bring those opportunities not just to K-State’s main campus, but also to its Olathe campus and the whole region.

“I have a strong appreciation for the critical role that K-State has to the future of the state of Kansas, and it is an honor for me to lead this great institution,” he said.

Since Schulz was named K-State presi-dent in February 2009, the university has made significant strides in its commit-ment to animal health, food safety and life sciences. Most recently, K-State was named a Center of Excellence in zoo-notic and animal disease defense and is set to receive $12 million from the U.S. Department of Homeland Security to support the endeavor.

“K-State’s research focus on zoonotic diseases and animal health, the unique research capabilities of the Biosecurity Research Institute and experienced and world-renowned faculty researchers all

aided the selection of K-State for this Center of Excellence,” Schulz said. “Because zoonotic diseases can spread from animals to humans and vice versa, this center will be important to protecting human health as well.”

As K-State’s president, Schulz also is impacting and influencing the growth of the Biosecurity Research Institute, a $54 million biosafety-level 3 facility

at K-State’s Pat Roberts Hall.

In November 2009 — less than two months after Schulz’s inau-guration — the Arthropod-Borne Animal Disease Research Labora-tory announced it was relocating to Manhattan be-

cause of the partnership with K-State and its location in the animal health corridor.

When Schulz joined K-State, he also inherited the enviable task of oversee-ing the progress of the National Bio and Agro-defense Facility, a more than $600 million federal research laboratory for animal health to be built on K-State’s campus.

Then on Nov. 12, the Greater Kansas City Community Foundation released a five-year progress report on its Time to Get It Right plan. The report noted K-State’s success in landing these two major federal laboratories and their abil-ity to bring economic development and translational research opportunities to the

region.Moreover, the report touted K-State’s

Olathe campus for increasing the university’s presence in the Kansas City metropolitan area for bringing forth pro-grams and resources that can strengthen the region’s education and research capacity.

Initially, K-State’s Olathe campus will focus on commercially viable applied research and technology discovery in animal health and in food safety and security. The campus’s first building is the National Institute for Animal Health and Food Safety, which broke ground in November 2009. The $28 million facility will house educational and lab spaces to support research, education and technol-ogy commercialization in animal health and food safety.

“I’m proud to see that so many of the great things K-State is doing for Kansas

are being recognized for their value to the greater Kansas City area,” Schulz said. “K-State’s Olathe campus is cer-tainly central to our engagement with the metropolitan area as a link to K-State’s many resources.”

Kirk Schulz leading K-State life sciences efforts in the region

K-State pushes onAn artist’s rendering of the K-State Olathe campus.

A preliminary rendering of the National Agro and Bio-defense Facility.

Kirk Schulz

Regents Distinguished Professor Jürgen Richt is one of K-State’s renowned animal health experts.

“K-State Olathe is certainly central to our engagement with the metropolitan area as a link

to K-State’s many resources.”

Kirk Schulz, K-State president


If you would like more information about advertising in these publications, please contact your local advertising representative or Glynelle Wells at 314.421.8340.

Missouri’s economic future is tied to biotech and life sciences. Follow important developments in these areas in Kansas City and St. Louis.

Focus onBiotechnology,Life Sciences,and Health Care

St. Louis Business Journal Focus Sections, Top 25 Lists and How To Articles

May 7 Health Care: Cancer

May 14 Technology

May 28 Missouri Research and Develoment Institutions List

June 25 Cancer Centers List

July 2 How to Choose an Intellectual Property Attorney

August 27 Health Care Heroes

Kansas City Business Journal Focus Sections

April 30 Biotech & Life Sciences

August 20 Biotech & Life Sciences, Focus on Animal Health



The Midwest’s Bio-Innovation Belt welcomes

Gold SponsorsEwing Marion Kauffman Foundation

Polsinelli Shughart PC

Thank you to summit sponsors

BY MICHAEL F. NICHOLS

Universities across Missouri and Kansas, as well as nearby states, have numerous research facilities and innovative programs that afford a wide range of world-class collaborative opportunities for existing businesses and start-up companies.

With several billions of dollars of research under way every year, these public and private institutions are cultivating distinctive expertise across the entire spectrum of plant-animal-human health research. We believe the global potential for this Bio-Innovation Belt is limitless, bringing important new jobs and businesses to the Midwest.

The University of Missouri System is pleased to bring together at this summit many of the chief researchers, businesses, policymakers and venture capitalists across the Midwest and beyond who are committed to implementing this vision.

The breadth and depth of strategically important initiatives in the region are considerable, and include:• Kansas State University’s new $600M+

National Bio and Agro-defense facility, which will be America’s first line of defense in the war against animal and agricultural disease. This lab will complement efforts of its biosafety level-3 lab for high-level research on food animals, food crops and food processing;•TheUniversityofKansas’researchstrengthsin

drug development and discovery, which encompass biomedical devices and bio-sensing technology that monitors brain chemistry during research on brain disorders such as Parkinson’s and Alzheimer’s diseases. KU is ranked second in the nation for NIH-funded pharmacy research;•WashingtonUniversity, a leadingNIH-funded

institution, which is home to numerous advanced medical technologies and a renowned Genome Sequencing Center; and• The University of Missouri’s regional

biosafety level-3 research facility, which includes an aerobiology suite for delivery of agents and therapeutics, as well as an animal lab that develops experimental models of infectious diseases. The

university’s strengths in infectious diseases research include West Nile Virus and tick-borne diseases, such as Lyme disease, Tularemia and Ehrlichiosis.

Also on Mizzou’s campus is America’s most powerful university-operated nuclear research reactor, which supports MU’s pioneering work in comparative human and animal health research, radioisotope production and nanomedicine.

The plant sciences research/commercialization activities spanning both states (with particular concentrations in the greater St. Louis area and extending westward) further the region’s research across the plant-animal-human health spectrum.

We invite businesses, entrepreneurs and investors to collaborate with our region’s collection of world-class scientists as our area strengthens its position as a globally recognized center for bio-innovations.

Michael F. Nichols is vice president for research and economic development at the University of Missouri System. He can be reached at 573-882-6726 or at [email protected].

Across Missouri, the University of Missouri’s four campuses are engaged in collaborations with businesses at 10 research commercialization facilities—not including work under way at 16 agriculture research facilities. For more information, please visit umsystem.edu/red.

entrepreneurs, collaborators, investors

University of Missouri SystemEnterprise Investment Program

The University of Missouri System invites start-up companies and entrepreneurs interested in collaborating with researchers at any of its four campuses to apply for funds from its newly announced Enterprise Investment Program.

The three-year, $5 million program will help fund start-up businesses in Missouri that are dedicated to moving the discoveries of university faculty from the laboratory to the marketplace, creating more high-quality jobs and building the state’s tax revenue base.

Evaluation of business plans and proposed use of the funds will begin this summer. Eligible parties must be:

• located in Missouri, • committed to commercializing university-

owned intellectual property, and• willing to grant the university an equity

interest in the venture.

For more information on the program or to apply, contact the University of Missouri Office of Research and Economic Development at (573) 882-6726.

Silver SponsorsAnalytical Bio-Chemistry Laboratories Inc.

Bayer Animal HealthCerner Corporation

JE Dunn ConstructionKCP&L

McCownGordon ConstructionSonnenschein Nath & Rosenthal LLP

Stinson Morrison Hecker LLPTeva Neuroscience

Bronze SponsorsBlue Cross and Blue Shield of Kansas City

Burns & McDonnellKansas City Area Development Council

Kansas City Southern Charitable FundNidus

Thompson Coburn LLP

Media SponsorsKansas City Business Journal

St. Louis Business Journal

Date post:	03-Sep-2014
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