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Mix it up. - Science · 2012-04-19 · XSERIES 2 ICP-MS, the model it replaces. The unique...

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Mix it up. RE-Mix Restriction Enzyme Master Mixes Restriction enzyme digests are now even easier! The same high quality restriction enzymes that you have come to trust from New England Biolabs are now available in master mix format, including enzyme, buffer and loading dye; simply add your DNA and digest. With RE-Mix Master Mixes take advantage of: • Simplified and shortened protocols • Fast digestion in 15 minutes (Time-Saver qualified) • High product quality with reproducible results RE-Mix Master Mixes – just add your DNA and mix For more information, visit www.NEBREMIX.com Blue-footed Booby (Sula nebouxii) © Tui De Roy L 5 min 15 min 1 hr o/n To experience the new restriction enzyme challenge from NEB, visit www.NEBcutitout.com G T AGC T T AG T C T C T GA GA T ACG G A C G A C
Transcript
Page 1: Mix it up. - Science · 2012-04-19 · XSERIES 2 ICP-MS, the model it replaces. The unique ion-focusing system in the iCAP Q delivers best-in-class signal-to-noise performance, and

Mix it up.RE-Mix

Restriction EnzymeMaster Mixes

Restriction enzyme digests are now even easier!

The same high quality restriction enzymes that

you have come to trust from New England Biolabs

are now available in master mix format, including

enzyme, buffer and loading dye; simply add your

DNA and digest.

With RE-Mix Master Mixes take advantage of:

• Simpli�ed and shortened protocols

• Fast digestion in 15 minutes

(Time-Saver quali�ed)

• High product quality

with reproducible results

RE-Mix Master Mixes – just add your DNA and mix

For more information, visit

www.NEBREMIX.comBlue-footed Booby (Sula nebouxii)

© Tui De Roy

L 5 min 15 min 1 hr o/n

To experience the new

restriction enzyme

challenge from NEB, visit

www.NEBcutitout.com

GTAGCT

T

AGT

CT

C

T

GA

GATACGG

A C

G

A

C

Page 2: Mix it up. - Science · 2012-04-19 · XSERIES 2 ICP-MS, the model it replaces. The unique ion-focusing system in the iCAP Q delivers best-in-class signal-to-noise performance, and

Else Kröner Fresenius

Immunology Award

Call for Candidates

In commemoration of the 25th anniversary

of the early death of Else Kröner, June 5,

2013, the Else Kröner-Fresenius-Stiftung

(Foundation) intends to award world-wide

pioneering discoveries in the field of medi-

cal immunology and to facilitate future re-

search by the winning individual or team.

The award - At least 500,000 € will be

awarded to the winner(s) in person.

Up to 3,500,000 € will be awarded for

future research.

The candidates must be fully active resear-

chers, who have made groundbreaking

discoveries in medical immunology. They

need to be in the position to accomplish

the research intended in the next 3-5 years.

Candidate nomination - Candidates will be

proposed by IUIS member associations.

Self-nominations need to be accompanied

by two letters of recommendation from at

least two internationally leading resear-

chers in immunology from two different

countries.

Deadline for nominations: July 4, 2012.

For further details please see www.ekfs.de

and www.iuis-online.org.

AAAS is here –bringing educational infrastructureto the developing world.

AAAS is helping the Rwandan government

rebuild its educational infrastructure as a way

to help drive economic growth and development.

By providing materials such as the Project 2061

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libraries, AAAS is helping the people of Rwanda

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technology. As a AAASmember your dues

support these efforts. If you’re not yet a AAAS

member, join us. Together we can make

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To learn more, visit

aaas.org/plusyou/rwanda

Page 3: Mix it up. - Science · 2012-04-19 · XSERIES 2 ICP-MS, the model it replaces. The unique ion-focusing system in the iCAP Q delivers best-in-class signal-to-noise performance, and

Congratulations to Dr. Tiago Branco on winning the 2011 Eppendorf & Science Prize for his studies on how

dendrites discriminate temporal input sequences and apply different integration rules depending on input

location. The results of Dr. Branco’s research provide insight on how the brain performs computations, and

suggest that even single neurons can solve complex computational tasks.

You could be the 11th winner of this award.

The annual Eppendorf & Science Prize for Neurobiology honors young scientists for their outstanding contribu-

tions to neurobiological research based on methods of molecular and cell biology. The winner and finalists are

selected by a committee of independent scientists, chaired by Science’s Senior Editor, Dr. Peter Stern.

To be eligible, you must be 35 years of age or younger. If you’re selected as this year’s winner, you will receive

US$ 25,000, have your work published in Science and be invited to visit Eppendorf in Hamburg, Germany.

Past winners and finalists have come from as far a field as China, Chile, India and New Zealand.

Yes, it can happen to you. Enter your research now!

Eppendorf & Science Prizefor Neurobiology

2011 Winner

Dr. Tiago Branco

Postdoctoral

Research Fellow

University College

London

Be the

next

winner!

Deadline for entries:

June 15, 2012

It´s easy to apply! Learn more at:

www.eppendorf.com/prize

Get recognized!

US$ 25,000 Prize

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Page 4: Mix it up. - Science · 2012-04-19 · XSERIES 2 ICP-MS, the model it replaces. The unique ion-focusing system in the iCAP Q delivers best-in-class signal-to-noise performance, and

LOCATION: Hemlock Bar

ARTICLE: Quantum Simulation

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The new Science Reader app for iPad® from AAAS puts Science in your

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Visit iTunes App StoreSM or content.aaas.org/ipad for details.

A new way to look at science

Page 5: Mix it up. - Science · 2012-04-19 · XSERIES 2 ICP-MS, the model it replaces. The unique ion-focusing system in the iCAP Q delivers best-in-class signal-to-noise performance, and

367www.sciencemag.org/products SCIENCE VOL 336 20 APRIL 2012

Newly offered instrumentation, apparatus, and laboratory materials of interest to researchers in all disciplines in academic, industrial, and governmental organizations are

featured in this space. Emphasis is given to purpose, chief characteristics, and availability of products and materials. Endorsement by Science or AAAS of any products or

materials mentioned is not implied. Additional information may be obtained from the manufacturer or supplier.

Electronically submit your new product description or product literature information! Go to www.sciencemag.org/products/newproducts.dtl for more information.

ECONOMY GC-MS SYSTEM

The GCMSQP2010 SE is an advanced standard gas chromatograph

mass spectrometer that combines the bene� ts of economy, simple op-

eration, and enhanced performance. The GCMS-QP2010 SE features

stable mass spectra that achieve high sensitivity and stability. The ion

optical system is optimized with a high-performance quadrupole mass

� lter and Optdesign simulation program to provide high-quality mass

spectra. Fully automated MS tuning allows users to optimize param-

eters easily and constantly to ensure stable mass spectra can always

be obtained. Enhanced maximum column � ow up to 4 mL/minute gives

users the ability to select from a variety of columns so that productiv-

ity and sample throughput can be dramatically increased. An optional

direct injection probe lets users easily obtain a mass spectrum when

analyzing materials that don’t lend themselves to chromatography. It

can also offer easy qualitative analysis without setting analytical pa-

rameters of the gas chromatograph.

Shimadzu Scienti� c Instruments

For info: 800-477-1227 www.ssi.shimadzu.com

COMPACT MASS SPECTROMETER

The Expression Compact Mass Spectrometer (CMS) is designed for

the discovery research and process development synthetic organic

chemistry market. Compact enough to operate in fume hoods and

space-restricted laboratories, chemists can have direct access to iden-

tify, monitor, and con� rm compounds rapidly as they are created in the

reactor. Moreover, the personal single quadrupole mass spectrometer

allows for rapid compound con� rmation in normal phase chromatogra-

phy fractions. Traditionally, chemists initiate a multihour reaction and

periodically withdraw samples for analysis in an open access mass

spectrometry lab. The remote analysis takes hours, decreasing the

usefulness of the information and building work� ow inef� ciencies.

Additionally, large numbers of normal phase puri� cation fractions are

generated and add to the central lab burden, further slowing vital feed-

back. The combination of a small footprint, critical design features, and

an intuitive software package permits operation within a fume hood or

next to existing bench instrumentation, allowing users access to fast

answers.

Advion

For info: 607-379-4565 www.advion.com

New Products: Mass Spectrometry

Pr Produoducedced by by th thee SciSciencencee/AA/AAASAS CusCustomtom Pu Publiblishishingng OffOfficeice LLIIFFEE SSCCIIEENNCCEE TTEECCHHNNOOLLOOGGIIEESS

MASS SPECTROMETERThe TripleQuad 4500 System is a new triple quadrupole system that

delivers 10x better sensitivity over competitive triple quadrupole sys-

tems in the same mid-level class. The new 4500 system is designed

to be the new ‘workhorse’ mass spectrometer with industry-leading

ruggedness. The 4500 system has the option of QTRAP technology,

which is recognized as delivering the world’s leading solution for si-

multaneous quantitation and library searching. The proprietary QTRAP

increases full-scan sensitivity by 100x over basic triple quadrupoles

by incorporating the world’s most sensitive Linear Accelerator Trap,

providing unmatched levels of con� dence in results for screening ap-

plications. To simplify the adoption of this next generation of LC/MS/

MS technology, new bundled solution packages called Accelerated

Lab Integration Packages are offered. These packages consist of not

only the mass spectrometer, but also the standards, software, training,

validation services, and a liquid chromatography (LC) system, includ-

ing the new Eksigent ekspert ultra 100 and 100-XL systems.

AB Sciex

For info: 877-740-2129 www.absciex.com

HIGH-SENSITIVITY ION SOURCE

The high-sensitivity ionBooster is an ion source designed to meet the

increasing demands for sensitivity enhancements in environmental

analysis, food testing, and forensics. Sensitivity gains of 5x to 100x

for many compounds extend the quantitative capability of modern

accurate-mass MS systems to the sensitivity range of high-end triple-

quadrupole instruments. The ion source enhances sensitivity and low-

ers detection limits by delivering more ef� cient ionization across a wide

range of applications. Inside the ionBooster, an electrospray is main-

tained at an elevated vaporizing temperature to enable enhanced de-

solvation of the analyte ions, even at high eluent � ow rates in UHPLC

separations with sharp chromatographic peaks. The exact response

with the ionBooster depends upon the type of compound and its specif-

ic chemical characteristics and thermal properties. In combination with

a maXis impact, a UHR-TOF system, accurate-mass data is obtained

across the full mass range, enabling qualitative analysis of unknowns,

analysis of multiple other drugs or target compounds, and retrospec-

tive screening of data for any target formula.

Bruker

For info: 510-683-4300 www.bdal.com

ICP-MS SYSTEM The new iCAP Q is an ICP-MS system featuring world-class performance and increased

throughput to help laboratories cut analysis times by up to 50% when compared to the

XSERIES 2 ICP-MS, the model it replaces. The unique ion-focusing system in the iCAP

Q delivers best-in-class signal-to-noise performance, and the proprietary QCell with

� atapole technology for low mass cut-off offers unparalleled interference removal for

complete con� dence in results. New Qtegra software fully automates the system for one-

click setup, which enables users to go from standby to performance-quali� ed analysis

with the push of a button. To ensure nearly continuous uptime, the iCAP Q is designed

to be easy to service. Access to the skimmer and sampler cones, the extraction lenses,

and the torch assembly make routine maintenance fast and easy. The iCAP Q is ideal for

environmental, metals, clinical research, food safety, semiconductor, and geochemical

laboratories conducting both routine and complex elemental analyses.

Thermo Fisher Scienti� c

For info: 800-532-4752 www.thermoscienti� c.com/dramatic

0420Product 367 4/12/12 1:00 PM

Page 6: Mix it up. - Science · 2012-04-19 · XSERIES 2 ICP-MS, the model it replaces. The unique ion-focusing system in the iCAP Q delivers best-in-class signal-to-noise performance, and

membercentral.aaas.org

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Page 7: Mix it up. - Science · 2012-04-19 · XSERIES 2 ICP-MS, the model it replaces. The unique ion-focusing system in the iCAP Q delivers best-in-class signal-to-noise performance, and

FuGENE is a registered trademark of Fugent, L.L.C. USA

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