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Mobile Phone Readout of Rapid Diagnostics for Infectious Disease
Kim Hamad-SchifferliFall 2015
Aedes aegyptiCDC.gov
Messina, Trends in Microbiology 2014
Threat of infectious diseases: Dengue• Mosquito borne disease• Disease burden: 2.5B people
at risk– >50M cases/year– >500K hospitalizations– Up to 5% fatality rates
• Emerging disease burden– Increasing dramatically
• No treatment, vaccine• Potential biothreat agent
NYTimes 2014
MMDx concept• Goal: Build point of care rapid diagnostic that is
multiplexed, machine readable, rugged, requires no special reagents, easy to use, cheap
• Provides diagnosis and real time reporting
Hand held diagnostic
Machine readableTime/GPS info
Map of diagnostic data
Image recognition and real-time monitoring
• Quantifies band intensity• Mobile phone readout app for Android: GIS data, time/date• No cradle• Open source• Flip phone
Mapping test GPS data
• GIS data uploaded to data base, Google Maps
Project Goals
• Mobile phone app that can:– Take image of diagnostic test– Analyze image and make diagnosis– Upload to server with time/location stamp
• System requirements:– Mobile phone (Android, maybe iPhone?)– Web server