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FRIEDRICH-ALEXANDER UNIVERSITÄT ERLANGEN-NÜRNBERG MEDIZINISCHE FAKULTÄT Module handbook of the master’s program in Molecular Medicine (Master of Science) (version 10/2018)
Transcript
Page 1: Module Handbook MolMed Master SS18 - FAU · Krebs, Prof. Dr. A. Boßerhoff and others 4 Module co ordinator Prof. S. von Hörsten 5 Contents • Animal Care and Protection • Relevant

FRIEDRICH-ALEXANDER UNIVERSITÄT ERLANGEN-NÜRNBERG

MEDIZINISCHE FAKULTÄT

Modulehandbook

ofthemaster’sprogramin

MolecularMedicine

(MasterofScience)

(version10/2018)

Page 2: Module Handbook MolMed Master SS18 - FAU · Krebs, Prof. Dr. A. Boßerhoff and others 4 Module co ordinator Prof. S. von Hörsten 5 Contents • Animal Care and Protection • Relevant

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Index

Index........................................................................................................................................................2

GeneralInformation................................................................................................................................4

ExaminationRegulations.........................................................................................................................4

AdvisorsintheMolecularMedicineMasterprogram ............................................................................4

Curriculum...............................................................................................................................................6

Area1-CompulsoryModules.................................................................................................................7

AdvancedLecturesinMolecularMedicine1 ..........................................................................................8

ArchitectureofBiopolymers .................................................................................................................11

LaboratoryAnimalScienceandBiologicalSafety..................................................................................13

AdvancedLecturesinMolecularMedicine2 ........................................................................................15

ResearchDesign ....................................................................................................................................18

Area2–ElectiveCompulsoryModulesA ..............................................................................................20

SeminarModuleA1.1:MolecularGeneticsandGenomics...................................................................21

SeminarModuleA1.2:MolecularMicrobiologyandImmunologyofInfection....................................23

SeminarModuleA1.3:MolecularImaging............................................................................................25

SeminarModuleA2.1:MolecularNeuroscience ...................................................................................27

SeminarModuleA2.2:EssentialConceptsinModernVirology............................................................29

SeminarModuleA2.3:Molecularandtranslationalconceptsofcardiacandrenaldisease ................31

SeminarModuleA3.1:MolecularOncology .........................................................................................33

SeminarModuleA3.2:CurrentConceptsofImmunology ....................................................................35

SeminarModuleA3.3:AnimalModelsinBiomedicalResearch ...........................................................37

ElectiveModule.....................................................................................................................................39

ProjectDevelopment ............................................................................................................................41

Area3–ElectiveCompulsoryModulesB..............................................................................................43

B1-ExternalModule.............................................................................................................................44

B2-ExternalModule.............................................................................................................................46

B3-LaboratoryResearchModule.........................................................................................................48

Area4–Master’sThesis .......................................................................................................................50

Master’sThesis......................................................................................................................................51

Master‘sColloquium .............................................................................................................................54

Page 3: Module Handbook MolMed Master SS18 - FAU · Krebs, Prof. Dr. A. Boßerhoff and others 4 Module co ordinator Prof. S. von Hörsten 5 Contents • Animal Care and Protection • Relevant

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Page 4: Module Handbook MolMed Master SS18 - FAU · Krebs, Prof. Dr. A. Boßerhoff and others 4 Module co ordinator Prof. S. von Hörsten 5 Contents • Animal Care and Protection • Relevant

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GeneralInformationThemaster’s program inMolecularMedicine at the FAU Erlangen-Nuremberg starts in thewinter

term.TheusualperiodforcompletingtheM.Sc.istwoyears(4semesters),afterwhichaPh.D.pro-gram can be started. The master’s program is based on the bachelor’s program “MolekulareMedizin”atFAUandprovidesanadvancededucationwiththegoalofpreparingstudentsforacareer

inbiomedicalresearch.Allcoursesofthemaster’sprogramaregiveninEnglish.

Toenterthemaster’sprogram,applicantsmusthavecompletedabachelor’sdegreewithhighaca-demicstandingfromarecognizeduniversity.

ApplicantsapplyonlinethroughthemasterapplicationportaloftheFAU: https://www.fau.eu/study/prospective-students/application-and-enrolment/applying-for-masters-

degree-programmes/

Themaster’sprogramincludescompulsory,electivecompulsoryandelectivemodules.Themaster’sthesisiscompletedduringthefourthsemester.Allmodulesaddupto120ECTScreditpoints.

Anexternalstayofuptosixmonthsduration–preferentiallyabroad-issuggestedforallstudents.

ExaminationRegulationshttps://www.fau.de/universitaet/rechtsgrundlagen/pruefungsordnungen/

AdvisorsintheMolecularMedicinemaster’sprogramStudents’DeanfortheprograminMolecularMedicineandHeadoftheauditcommitteeProf.Dr.AnjaBoßerhoffLehrstuhlfürBiochemieundMolekulareMedizin

Friedrich-Alexander-UniversitätErlangen-NürnbergFahrstr.17,91054Erlangen,Office/Room03.036Tel.:091318524190

mail:[email protected]

CoordinatorandadvisorforthestudyprograminMolecularMedicineDr.SimoneReiprichDean’sofficeoftheFacultyofMedicine

Friedrich-Alexander-UniversitätErlangen-NürnbergKrankenhausstr.12,91054Erlangen,Office/RoomG02.231Tel.:091318524687

mail:[email protected]

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Abbreviations

L Lecture

T TutorialS SeminarP PracticalTraining

FAU Friedrich-Alexander-UniversityErlangen-Nürnberg

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Curriculum

CurricularCategoriesandModuleNames ECTS Semester

Area1–CompulsoryModules 35

AdvancedLecturesinMolecularMedicine1 10 1.

LaboratoryAnimalScienceandBiologicalSafety 5 1.

ArchitectureofBiopolymers 5 1.

AdvancedLecturesinMolecularMedicine2 10 2.

ResearchDesign 5 2.

Area2–ElectiveCompulsoryModulesA 30

ElectiveModule 5 1.

ElectiveCompulsorySeminarModule1 5 1.

ElectiveCompulsorySeminarModule2 5 2.

ElectiveCompulsorySeminarModule3 5 3.

ProjectDevelopment 10 3.

Area3–ElectiveCompulsoryModulesB 25

ExternalModule/s,LaboratoryResearchModules 25 2.+3.

Area4–Master‘sThesis 30

Master’sThesis 25 4.

Master’sColloquium 5 4.

120

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Area1-CompulsoryModules

CurricularCategoryandModuleNames ECTS Semester

Area1-CompulsoryModules 35 Areagrade

AdvancedLecturesinMolecularMedicine1 10 1. Graded

LaboratoryAnimalScienceandBiologicalSafety 5 1. Pass/fail

ArchitectureofBiopolymers 5 1. Graded

AdvancedLecturesinMolecularMedicine2 10 2. Graded

ResearchDesign 5 2. Graded

Theareagradeiscalculatedastheaverageofthemodulesweightedbythemodules’ECTSpoints.Thearea1gradecontributesapprox.29%tothefinalmaster’sgrade(35/120ECTS).

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ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea1-CompulsoryModules

8

AdvancedLecturesinMolecularMedicine11 Modulename 2430-AdvancedLecturesinMolecularMedicine1 10ECTS

2 Courses/lectures

-V:Immunology(2SWS)-V:MolecularNeuroscience(2SWS)-V:MolecularImaging(2SWS)

3 Lecturers Prof.Dr.C.Bogdan,Prof.Dr.D.Vöhringer,Prof.Dr.K.Prof.Dr.G.Kröncke,Prof.Dr.D.Dudziak,,Prof.Dr.C.Alzheimer,Prof.Dr.R.Enz,Prof.Dr.J.Winkler,Prof.Dr.D.C.Lie,Prof.Dr.T.Bäuerleandothers

4 Modulecoordinator Prof.Dr.Enz

Lecturecoordinators:Prof.Bogdan(Immunology),Prof.Enz(Neuroscience),Prof.Lie(Imaging)

5 Contents

Lecture:ImmunologyMechanisms,modelsandconcepts

• Evolution,components,functionanddysfunctionoftheimmunesystem• Anti-infectiousimmuneresponse:innate,TandBcell-mediatedimmu-

nity• Terminationoftheimmuneresponse,resolutionofinflammationand

tissuerepair• Tumorimmunology

Medicalaspects• Allergies,autoimmunity,chronicinflammatoryandautoinflammatory

diseases,immunodeficiencies,graftvs.hostdisease• Immunotherapy,antibodiesandvaccination

SpecifictechniquesandmethodsinimmunologyLecture:MolecularNeuroscienceMechanisms,modelsandconcepts

• Neurocytologyandsynapses

• Learning,memory,dementiaandsleep• Sensorysystems:Pain,Hearing,Vision

• Plasticityinthecentralnervoussystem• Braindevelopment

Medicalaspects

• Neurodegenerativediseasesandstroke• Psychiatricdiseases

Specifictechniquesandmethodsinneuroscience

Lecture:MolecularImagingMechanisms,modelsandconceptsPrinciplesofimagingandmanipulationofcell-biologicalundmolecularprocesses

MedicalaspectsPreclinicalmodelsforhumandiseases(CNSDiseases,Oncology)Specifictechniquesandmethodsinmolecularimaging

• opticalimaging

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ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea1-CompulsoryModules

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• transgenicreportersforopticalimaging• MagneticResonanceImaging• SPECTundPET• optogenetics

6 Learningobjectivesandskills

Thestudents

• obtainprofoundknowledgeintheabovedescribedcontents.

• understandprinciplemolecularandcellularmechanismsandtheirinter-playinthenervousandimmunesystems.

• understandbasicandstate-of-the-artconceptsinimagingofbiomedi-callyrelevantmolecularandcellbiologicalprocesses.

• transferobtainedtheoreticalandmethodologicalknowledgetoresearch

projectsandtoclinicalsettingsincludingmoleculartherapiesanddiag-nostics.

7 Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine

8 Integrationincurricu-lum

Compulsorymodule,1stsemester

9 Modulecompatibility M.Sc.MolecularMedicine

10 Methodofexamina-

tion

Writtenexam,180min,openquestionsandmultiplechoice(24301)

11 Gradingprocedure Gradeofthewrittenexam

12 Modulefrequency Annuallyinthewinterterm

13 WResitexamination Twice

14 Workload Classtime:90hStudytime:210h

15 Moduleduration 1term

16 Teachingandexami-nationlanguage

English

17 Recommendedrea-ding

ImmunologyCellularandMolecularImmunology,eds.Abbas,LichtmanandPillai,Elsevier-

Saunders,newestedition;Janeway´sImmunobiology,eds.Murphy,TraversandWalport,GarlandScience,newstedition

NeurosciencePrinciplesinNeuralScience,Ed.Kandel,Schwartz,Jessel,McGrawHill

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ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea1-CompulsoryModules

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BasicNeurochemistry,Ed.Siegel,Albers,Brady,Price,AcademicPress

newesteditions

ImagingWeisslederetal.,MolecularImaging,People’sMedicalPublishingHouse,newestedition

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ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea1-CompulsoryModules

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ArchitectureofBiopolymers1 Modulename 2440-ArchitectureofBiopolymers 5ECTS

2 Courses/lectures

S:ArchitectureofBiopolymers(2SWS)MandatoryAttendanceT:Computer-basedtutorialtoArchitectureofBiopolymers(2SWS)

3 Lecturers Prof.Dr.H.Stichtandothers

4 Modulecoordinator Prof.Dr.H.Sticht

5 Contents

Mechanisms,modelsandconcepts• Principlesofproteinstructureanditsroleforproteinfunction.• Alterationsofproteinstructureandemergenceofdisease.• Elementsofproteinstructure• Effectofmutationsonproteinstabilityandfunction

Specifictechniquesandmethodsinstructuralbiochemistrywithmedicalaspects• Computationalanalysisofbiomolecularstructuresandofdisease-

associatedproteinmutations.• Methodsforstructuredetermination• Proteindatabasesandtheirrespectivedataformats• Methodsforinsilicodataanalysis• Structuresofmedicallyimportantproteinclasses(e.g.kinases,prote-

ases,nucleicacidbinding,ortransmembraneproteins)• Linearsequencemotifsandproteininteractiondomains• Post-translationalmodifications• Protein(mis-)foldingandaggregation• Proteindesign• Visualizationofmolecularstructures• Analysisofinteractingmolecularsurfaces

6 Learningobjectives

andskills

Thestudents

• gaininsightintothestructuralprinciplesofbiopolymersandtheirimpli-cationsonfunction

• acquireprofoundandhands-onknowledgeofimportantconcepts,data-bases,tools,andmethodsinstructuralandcomputationalbiology

• areabletodescribeandtoapplythesemethodstorelatedproblemsinthefieldofstructuralbiology

• presentandcriticallydiscussscientificfindingsinseminartalks• gainexperiencewithatoolsetofcomputationalmethodsandvisualiza-

tionprogramsthattheycanapplytotheirfurtherstudiesandresearchprojects

7 Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine

8 Integrationincurricu-lum

Compulsorymodule,1stsemester

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ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea1-CompulsoryModules

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9

Modulecompatibility M.Sc.MolecularMedicine

10 Methodofexamina-

tion

Portfolio

1.Writtenexam,60min,multiplechoicequestions(24402)2.Presentationwithdiscussion(approx.30min)(24401)

11 Gradingprocedure Gradeofthewrittenexam

12 Modulefrequency Annuallyinthewinterterm

13 WResitexamination Twice

14 Workload Classtime:60hStudytime:90h

15 Moduleduration 1term

16 Teachingandexami-nationlanguage

English

17 Recommendedrea-

ding

Literatureprovidedontheinstitute’shomepage:

http://www.biochem.uni-erlangen.de/studium/index.php„DownloadsBiopolymers“(passwordneeded)

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ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea1-CompulsoryModules

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LaboratoryAnimalScienceandBiologicalSafety1 Modulename 2450–

LaboratoryAnimalScienceandBiologicalSafety5ECTS

2 Courses/lectures

-L:LaboratoryAnimalScienceincludingWelfareforpersonscarryingoutanimalexperiments(1SWS)MandatoryAttendance(20hre-quired)-P:Animaltechniquesforpersonscarryingoutanimalexperiments(1.5SWS)MandatoryAttendance(20hrequired)-L:BiologicalSafety(1SWS)

3 Lecturers Prof.Dr.S.vonHörsten,Dr.Schwarz,Dr.R.Jurgons,Dr.Schulze-Krebs,Prof.Dr.A.Boßerhoffandothers

4 Modulecoordinator Prof.S.vonHörsten

5 Contents

AnimalCareandProtection• Relevantlegalprovisions(nationalandinternational)• Ethicalaspectsofworkingwithlaboratoryanimals• the3Rprinciple:“replace,reduce,refine”• Biologyandhousingofthemostimportantlaboratoryanimalspecies• Physiologicalrequirements• Diseasesoflaboratoryanimals,zoonoses,hygieneinanimalhousing• Assessmentofstressandmeasuresfortheavoidanceofpainandsuffer-

ance• Planningandtheoreticalexecutionofanimalexperiments• Behavioroflaboratoryanimalsandspecies-appropriatehandling• Administrationofsubstances• Techniquesofsamplewithdrawal• Killingtechniques• anesthesiology,analgesiaandbasicprinciplesofsurgery

Thestudentsobtainacertificateforpersonscarryingoutanimalexperiments(FELASACategoryB)(“FachkundenachweisnachdenFELASABRichtlinien”).Thecontents,durationandrealizationofthiscourseadheretoofficialregulationsandFELASArecommendations.Theattendanceofthelecture(20h)andpracticalexercises(20h)arethereforemandatory. BiologicalSafety

• Riskpotentialofworkingwithgeneticallymodifiedorganisms(GMO)• RiskpotentialofGMOsrelease• Legalprovisionsandsecuritymeasuresforlaboratoriesanddivisions

workingwithGMOs• Healthandsafetymeasures

Studentscanobtainthe„FachkundenachweisProjektleiterfürdieBiologischeSicherheitnach§15undS17GenTSV“.

6 Learningobjectives

andskills

Thestudents

• knowandunderstandthelegalprerequisitesforworkingwithlaboratoryanimalsandgeneticallymodifiedorganisms

• reflecttheethicalaspectsofanimaltestingandgeneticengineering• becomeacquaintedandtrainedinanimalhandlingandstandardlabora-

toryanimaltechniques(mouse,rat,largeanimal)

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ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea1-CompulsoryModules

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7 Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine

8 Integrationincurricu-

lum

Compulsorymodule,1stsemester

9

Modulecompatibility M.Sc.MolecularMedicine

10 Methodofexamina-tion

Practicalexam120min(24501)

11 Gradingprocedure Pass/fail

12 Modulefrequency Annuallyinthewinterterm

13 WResitexamination Twice

14 Workload Classtime:50hStudytime:110h

15 Moduleduration 1term

16 Teachingandexami-

nationlanguage

English

17 Recommendedrea-ding

Script„AnimalCareandProtection“GrundlagenderVersuchstierkunde,vanZutphen,Baumans,Beynen,neuesteAuflage,GustavFischerISBN3-437-20532-3

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ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea1-CompulsoryModules

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AdvancedLecturesinMolecularMedicine21 Modulename 2435-AdvancedLecturesinMolecularMedicine2 10ECTS

2 Courses/lectures

L:MolecularOncology(2SWS)L:MolecularEmbryology(2SWS)L:MolecularGeneticsandSystemsMedicine(2SWS)

3 Lecturers Prof.Dr.J.Behrens,Prof.Dr.A.Boßerhoff,Prof.Dr.T.Brabletz,Prof.Dr.M.Stürzl,Prof.Dr.M.Wegner,Prof.Dr.F.Engel.Prof.Dr.A.Reis,Prof.Dr.A.Winterpacht,Prof.Dr.J.Vera-Gonzalezandothers

4 Modulecoordinator Prof.Dr.M.Wegner

Lecturecoordinators:Prof.Behrens(Oncology),Prof.Wegner(Embryology),

Prof.Reis(GeneticsandSystemsMedicine)

5 Contents

MolecularOncologyMechanisms,modelsandconcepts

• Generaltumorcellbiology• Oncogenesandtumorsuppressorgenes• Oncogenicsignalingpathways• Cellcycleandregulationofcelldeath• Transcriptionandepigenetics• Metabolomicsandcancer• Multisteptumorigenesis• Tumormicroenvironment• Invasionandmetastasis• Genomeintegrity• Conceptoftumorstemcells• Tumorangiogenesisandimmunology• Animalmodelsinoncology

Medicalaspects• Moleculartherapies• Molecularclassification• Moleculardiagnosis• Translationalaspects

SpecifictechniquesandmethodsinmolecularoncologyMolecularEmbryologyMechanisms,modelsandconcepts

• Principlesofhumandevelopment• Developmentalprinciplesofbiomedicallyrelevantmodelorganisms• Intrinsicandextrinsicregulatorypathwaysofdevelopment• EarlyembryonicdevelopmentofC.elegans,D.melanogasterandverte-

brates• Axisformation,germlayerformation,sexdetermination• Mesodermaldevelopment• Ectodermalandneuralcrestdevelopment

Medicalaspects• inbornerrorsofdevelopmentascauseofdisease

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• malformationsandsyndromes• pleiotropy

SpecifictechniquesandmethodsinmolecularembryologyMolecularGeneticsandSystemsMedicineMechanisms,modelsandconcepts

• ModulationofpenetranceinMendeliandiseases• Molecularbasisofcomplexdiseases• Epigeneticmechanisms• Gene-andgenomeregulation• Geneticapproachesusinganimalmodels• Statisticalinterpretationoflargedatasets• Quantitativetraitloci• Analysis,reconstructionandmodellingofbiologicalsystemsandnet-

worksMedicalaspects

• geneticandepigeneticchangesunderlyinghumandisease• physiologyandpathophysiologyofgeneticallydeterminedbiological

processesSpecifictechniquesandmethodsinmoleculargeneticsandsystemsmedicine

6 Learningobjectives

andskills

Thestudents

• gainknowledgeintheabovementionedcontents.• Understandbasicandmodernconceptsofbiochemicalsystems,molecu-

larandcellularoncology,molecularembryologyandmoleculargenetics.• gaininsightintothemechanismsunderlyingdevelopmentandselected

developmentaldisorders,tumorbiology,geneticandepigeneticmisregu-lationinselecteddisorders.

• transferobtainedtheoreticalandmethodologicalknowledgetoresearchprojectsandtoclinicalsettingsincludingmoleculartherapiesanddiag-nostics.

• utilizebiostatisticalmethodsandoperatestandardsoftwaretoolsfornetworkanddataanalyses.

• develop,interpret,evaluateanddiscussbiochemicalnetworksandsta-tisticalanalysesofbiologicaldata

7 Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine

8 Integrationincurricu-lum

Compulsorymodule,2ndsemester

9 Modulecompatibility M.Sc.MolecularMedicine

10 Methodofexamina-tion

Writtenexam,180min,openandmultiplechoicequestions(24351)

11 Gradingprocedure Gradeofthewrittenexam

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ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea1-CompulsoryModules

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12 Modulefrequency Annuallyinthesummerterm

13 WResitexamination Twice

14 Workload Classtime:90hStudytime:210h

15 Moduleduration 1term

16 Teachingandexami-nationlanguage

English

17 Recommendedrea-

ding

Oncology

RobertA.Weinberg,TheBiologyofCancer,2ndedition,GarlandScience

EmbryologySelectedchaptersfromScottF.Gilbert:DevelopmentalBiology(SinauerPress)or

LewisWolpert:PrinciplesofDevelopment(OxfordUniversityPress),Newesteditions

MolecularGeneticsSelectedchaptersfromTomStrachanandAndrewRead:HumanMolecularGe-

netics(GarlandScience)orTomStrachanetal.:GeneticsandGenomicsinMedi-cine(GarlandScience),newesteditions

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ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea1-CompulsoryModules

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ResearchDesign1 Modulename 2445-ResearchDesign 5ECTS

2 Courses/lectures S:ProjectandProposalDesign(3SWS)MandatoryAttendance

3 Lecturers Prof.Dr.Behrens,Prof.Dr.Brabletz,Prof.Dr.Lie,Prof.Dr.Stürzlandothers

4 Modulecoordinator Prof.Dr.Behrens

5 Contents DevelopmentofscientificprojectsGrant/paperwritingstrategiesGoodscientificpractice

6 Learningobjectives

andskills

Thestudents

• areabletoperformliteraturesearchesandtocriticallysummarizethestateoftheart

• applytheobtainedknowledgetogeneratescientifichypotheses• learnhowtodevelopandformulateascientificresearchprogramtotest

thesehypothesesadheringtotherulesofgoodscientificpractice• acquireskillsinscientificwritingofresearchpapers,projectplansand

grants• presentanddiscussprojectproposalsinoralpresentations

7 Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine

8 Integrationincurricu-

lum

Compulsorymodule,2ndsemester

9 Modulecompatibility M.Sc.MolecularMedicine

10 Methodofexamina-tion

Seminarpresentation30min(24451)andtermpaper7-10pages(24452)

11 Gradingprocedure Gradeofthetermpaper

12 Modulefrequency Annuallyinthesummerterm

13 WResitexamination Twice

14 Workload Classtime:45hStudytime:105h

15 Moduleduration 1term

16 Teachingandexami-

nationlanguage

English

17 Recommendedrea- Booklet“SafeguardingGoodScientificPractice”(DFG)

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ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea1-CompulsoryModules

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ding

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Area2–ElectiveCompulsoryModulesA

CurricularCategoryandModuleNames ECTS Semester

Area2–ElectiveCompulsoryModulesA 30 Areagrade

SeminarModule1 5 1. Graded

SeminarModule2 5 2. Graded

SeminarModule3 5 3. Graded

ElectiveModule 5 1. Pass/fail

ProjectDevelopment 10 3. Graded

Theareagradeiscalculatedastheaverageofthemodulesweightedbythemodules’ECTSpoints.

Thearea2gradecontributes25%tothefinalmaster’sgrade(30/120ECTS).

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ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea2–ElectiveCompulsoryModules

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1810-SeminarModuleA1.1:MolecularGeneticsandGenomics1 Modulename A1.1–MolecularGeneticsandGenomics(2460) 5ECTS

2 Courses/lectures S:(2SWS)MandatoryAttendance

3 Lecturers Prof.Dr.A.Reis,Prof.Winterpachtandothers

4 Modulecoordinator Prof.Dr.A.Reis

5 Contents

Thestudentspresentanddiscussbasicprinciplesof moleculargeneticsandge-nomicsusingselectedkeypublicationsfromscientificjournals.Theseminarcoversthefollowingaspects:

• Mechanismsofgeneregulation• Genomicarchitectureandphenotypicvariability• Wholegenomesequencingapproachesforunderstandinggeneticvaria-

tion• Molecularbasisofcomplexdiseases• Molecularmechanismsofepigeneticregulationandinheritance• Animalmodelsindissectinggeneticcomponentsofcomplextraits• Interpretationoflargegenomicdatasets

6 Learningobjectives

andskills

Thestudents

• obtainprofoundsubject-specificknowledgeinmoleculargeneticsandgenomics

• obtainskillsforacriticalanalysisandinterpretationofscientificdata.• read,presentandanalyzecurrentprimaryscientificliterature• independentlysolveproblemsinthefieldofmoleculargeneticsandpre-

senttheirsolutionsinoralandwrittenform• traintheirabilityfordiscussionandteamworkbyworkinginsmall

groups• giveandreceivecriticalfeedbacktoandfromfellowstudents

7 Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine

8 Integrationincurricu-

lum

Electivecompulsorymodule,1stsemester

9

Modulecompatibility M.Sc.MolecularMedicine

10 Methodofexamina-tion

Presentation30min(24601)andtermpaper15-20pages(24602)

11 Gradingprocedure Gradeofthetermpaper

12 Modulefrequency Annuallyinthewinterterm

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13 WResitexamination Twice

14 Workload Classtime30h

Studytime120h

15 Moduleduration 1term

16 Teachingandexami-nationlanguage

English

17 Recommendedrea-

ding

TomStrachanetal.:GeneticsandGenomicsinMedicine(GarlandScience),new-

estedition

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1810-SeminarModuleA1.2:MolecularMicrobiologyandImmunologyofInfection

1 Modulename A1.2–MolecularMicrobiologyandImmunologyofInfection(2465)

5ECTS

2 Courses/lectures S:MicrobiologyandImmunologyofInfection(2SWS)MandatoryAttendance

3 Lecturers Prof.Dr.D.Vöhringer,Prof.Dr.S.Krappmann,PDDr.A.Lührmannandothers

4 Modulecoordinator Prof.Dr.med.C.Bogdan

5 Contents

MolecularMicrobiologyandImmunologyofInfectionThestudentspresentanddiscussbasicprinciplesofhost-pathogeninteractions,cellularandmolecularregulationofimmuneresponses,defensemechanismsagainstpathogensandmolecularescapestrategiesusingselectedkeypublica-tionsfromscientificjournals.Theseminarcoversthefollowingaspects:

• Adhesionandinvasionofpathogens• Bacterialsecretionsystems• Modulationofintracellulartransportofproteinsandvesicles• Bacterialtoxins• Pathogenrecognitionandinnateimmunity• Diversity,plasticityandfunctionofThelpercells• AntiviralfunctionsofCD8Tcells• Innatelymphoidcells• Fungalpathogens• Secondarymetabolitesoffungi• Immuneresponsetofungi• Protozoaninfectionsandimmuneresponse• Pathogenicityofhelminths• Immuneresponsetohelminths• Immuneevasionofinfectiouspathogens,pathogenpersistence

6 Learningobjectives

andskills

Thestudents

• obtainprofoundsubject-specificknowledgeinmolecularmicrobiologyandimmunologyofinfection.

• obtainskillsforacriticalanalysisandinterpretationofscientificdata.• read,presentandanalyzecurrentprimaryscientificliterature• independentlysolveproblemsinthefieldofmicrobiologyandimmunol-

ogyofinfectionandpresenttheirsolutionsinoralandwrittenform• traintheirabilityfordiscussionandteamworkbyworkinginsmall

groups• giveandreceivecriticalfeedbacktoandfromfellowstudents

7 Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine

8 Integrationincurricu- Electivecompulsorymodule,1stsemester

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lum

9

Modulecompatibility M.Sc.MolecularMedicine

10 Methodofexamina-tion

Presentation30min(24651)andtermpaper15-20pages(24652)

11 Gradingprocedure Gradeofthetermpaper

12 Modulefrequency Annuallyinthewinterterm

13 WResitexamination Twice

14 Workload Classtime30h

Studytime120h

15 Moduleduration 1term

16 Teachingandexami-nationlanguage

English

17 Recommendedrea-

ding

1. General

• Schaibleetal.IntracellularNichesofMicrobes:aPathogensGuideThroughtheHostCell(1sted.2009);

• Salyers and Witt: Bacterial Pathogenesis (3rd ed. January 2011)• Kaufmann,Rouse,Sacks:TheImmuneResponsetoInfection(1sted.

2011);• Abbas,Lichtman,PillaiCellularandMolecularImmunology,8thed.2015

2. Specificprimaryliterature(originalarticles,reviewarticles)willbehandedouttothestudents

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1810-SeminarModuleA1.3:MolecularImaging1 Modulename A1.3–MolecularImaging(2470) 5ECTS

2 Courses/lectures S:MolecularImaging(2SWS)MandatoryAttendance

3 Lecturers Prof.Dr.D.C.Lie,Prof.Dr.T.Bäuerleandothers

4 Modulecoordinator Prof.Dr.D.C.Lie

5 Contents

Thestudentspresentanddiscussbasicprinciplesofkeymethodsinmolecularimagingusingselectedkeypublicationsfromscientificjournals.Thestudentsareintroducedtotheoreticalandpracticalaspectsof

• opticalimagingmethods• smallanimalimaging• transgenicreporterdesign

6 Learningobjectivesandskills

Thestudents

• obtainprofoundsubject-specificknowledgeinmolecularimaging.• obtainskillsforacriticalanalysisandinterpretationofscientificdata.• read,presentandanalyzecurrentprimaryscientificliterature.• transfertheoreticalknowledgeinimagingtechnologiestoresearchpro-

jects.• judgethetechnologicalrequirementsofbiomedicalimagingmethods

andpresenttheirsolutionsinoralandwrittenform.• getexperienceinpreparingprobesforbiomedicalimaging.• traintheirabilityfordiscussionandteamworkbyworkinginsmall

groups.• giveandreceivecriticalfeedbacktoandfromfellowstudents

7 Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine

8 Integrationincurricu-lum

Electivecompulsorymodule,1stsemester

9

Modulecompatibility M.Sc.MolecularMedicine

10 Methodofexamina-tion

Presentation30min(24701)andtermpaper15-20pages(24702)

11 Gradingprocedure Gradeofthetermpaper

12 Modulefrequency Annuallyinthewinterterm

13 WResitexamination Twice

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14 Workload Classtime:30h

Studytime:120h

15 Moduleduration 1term

16 Teachingandexami-nationlanguage

English

17 Recommendedrea-

ding

Weisslederetal.,MolecularImaging,People’sMedicalPublishingHouse,newest

edition

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1820-SeminarModuleA2.1:MolecularNeuroscience1 Modulename A2.1–MolecularNeuroscience(2475) 5ECTS

2 Courses/lectures Seminar(2SWS),MandatoryAttendance

3 Lecturers Prof.Dr.C.Alzheimer,Prof.Dr.R.Enz,Prof.Dr.J.Kornhuber,Prof.Dr.J.Winkler,Prof.Dr.M.Wegnerandothers

4 Modulecoordinator Prof.Dr.R.Enz

5 Contents

Thestudentspresentanddiscussbasicprinciplesofneuroscienceusingselectedkeypublicationsfromscientificjournals.Theseminarcoversthefollowingaspects:

• Molecularprinciplesofsynapticneurotransmission• Higherbrainfunctions(e.g.learningandmemory,dementia,sleep)• Sensorysystems• Plasticityinthecentralnervoussystem• Molecularcausesofdisordersinthenervoussystem(e.g.blindness,

neurodegenerativediseases,depression,addiction,stroke)• Glialbiologyanddisease• Musclebiologyanddisease• Presentationofpatientsintheneurologydepartment

6 Learningobjectivesandskills

Thestudents

• obtainprofoundsubject-specificknowledgeinmolecularandclinicalneuroscience.

• obtainskillsforacriticalanalysisandinterpretationofscientificdata.• read,presentandanalyzecurrentprimaryscientificliteratureembed-

dedwithintheup-to-datescientificandtherapeuticbackground.• learnthedesignofexperimentalstrategiesandtechniquessuitedtoan-

swerscientificquestionsandpresenttheirsolutionsinoralandwrittenform.

• traintheirabilityfordiscussionandteamworkbyworkinginsmallgroups.

• giveandreceivecriticalfeedbacktoandfromfellowstudent.

7 Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine

8 Integrationincurricu-lum

Electivecompulsorymodule,2ndsemester

9

Modulecompatibility M.Sc.MolecularMedicine

10 Methodofexamina-

tion

Presentation30min(24751)andtermpaper15-20pages(24752)

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11 Gradingprocedure Gradeofthetermpaper

12 Modulefrequency Anuallyinthesummerterm

13 WResitexamination Twice

14 Workload Classtime30h,Studytime:120h

15 Moduleduration 1term

16 Teachingandexami-

nationlanguage

English

17 Recommendedrea-ding

PrinciplesinNeuralScience,Ed.Kandel,Schwartz,Jessel,McGrawHillBasicNeurochemistry7.Auflage,Ed.Siegel,Albers,Brady,Price,AcademicPress

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1820-SeminarModuleA2.2:EssentialConceptsinModernVirology1 Modulename A2.2–EssentialConceptsinModernVirology(2480) 5ECTS

2 Courses/lectures S:EssentialConceptsinModernVirology(2SWS)MandatoryAttendance

3 Lecturers Prof.Dr.K.Überla,Prof.Dr.M.Marschall,Prof.Dr.T.Stammingerandothers

4 Modulecoordinator Prof.Dr.ManfredMarschall

5 Contents

Lectureserieswithexercisesinmodernvirology.Thestudentspresentanddis-cussbasicprinciplesofmolecularandmedicalvirologyusingselectedcurrentand/orclassicalpublicationsfromscientificjournals.Theseminarcoversthefollowingaspects:

• antiviraltherapyandprophylaxis• vaccinationstrategies• tumorigenictransformationmediatedbyviruses• epigeneticsofviralgenomes• viralregulatoryproteins• virus-basedvectors• immunecontrolofviralinfections

6 Learningobjectivesandskills

Thestudents

• obtainprofoundsubject-specificknowledgeinmolecularandmedicalvi-

rology.• obtainskillsforacriticalanalysisandinterpretationofscientificdata.• read,present,analyzeandevaluatecurrent/classicalprimaryscientific

literature.• learnthedesignofexperimentalstrategiesandtechniquessuitedtoan-

swerscientificquestionsandpresenttheirsolutionsinoralandwrittenform.

• traintheirabilityfordiscussionandteamworkbyworkinginsmallgroups.

• giveandreceivecriticalfeedbacktoandfromfellowstudent.

7 Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine

8 Integrationincurricu-lum

Electivecompulsorymodule,2ndsemester

9 Modulecompatibility M.Sc.MolecularMedicine

10 Methodofexamina-tion

Presentation30min(24801)andtermpaper15-20pages(24802)

11 Gradingprocedure Gradeofthetermpaper

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12 Modulefrequency Annuallyinthesummerterm

13 WResitexamination Twice

14 Workload Classtime:30hStudytime:120h

15 Moduleduration 1term

16 Teachingandexami-nationlanguage

English

17 Recommendedrea-

ding

Willbedeterminedindividuallybypreparingdiscussionswiththespecifictutors.

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1820-SeminarModuleA2.3:Molecularandtranslationalconceptsofcardiacandrenaldisease

1 Modulename A2.3–Molecularandtranslationalconceptsofcar-diacandrenaldisease(2485)

5ECTS

2 Courses/lectures S:Seminar(2SWS)MandatoryAttendance

3 Lecturers Prof.Dr.K.-U.Eckardt,Prof.Dr.F.Engel,Prof.Dr.C.Korbmacher,Prof.Dr.A.Ludwig,Prof.Dr.T.Volk

4 Modulecoordinator Prof.Dr.T.Volk

5 Contents

Thestudentspresentanddiscussbasicprinciplesofheartandremaldiseasesusingselectedkeypublicationsfromscientificjournals.Theseminarcoversthefollowingaspects:

• Molecular,pathophysiologicalandpathologicalcauses,signalingcas-cadesandmechanismsofhumancardiac,renalandcirculatorydiseasesincludingheartfailure,cardiacarrhythmia,tubularandglomerulardis-ease,renalfailureandhypertension.

• up-to-dateexperimentalapproaches,techniquesandtranslationalcon-ceptsinphysiology,pharmacology,pathologyandexperimentalmedi-cine.

6 Learningobjectivesandskills

Thestudents• obtainprofoundsubject-specificknowledgeandsubstantialexpertisein

understandingmolecularmechanismsofdiseasedevelopmentandpro-

gression.• obtainskillsforacriticalanalysisandinterpretationofscientificdata.• read,present,analyzeandevaluatecurrentprimaryandreviewlitera-

ture.• learnthedesignofexperimentalstrategiesandtechniquessuitedtoan-

swerscientificquestionsandpresenttheirsolutionsinoralandwrittenform.

• traintheirabilityfordiscussionandteamworkbyworkinginsmallgroups.

• giveandreceivecriticalfeedbacktoandfromfellowstudent.

7 Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine

8 Integrationincurricu-lum

Electivecompulsorymodule,2ndsemester

9 Modulecompatibility M.Sc.MolecularMedicine

10 Methodofexamina-

tion

Presentation30min(24851)andtermpaper15-20pages(24852)

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11 Gradingprocedure Gradeofthetermpaper

12 Modulefrequency Annuallyinthesummerterm

13 WResitexamination Twice

14 Workload Classtime:30hStudytime:120h

15 Moduleduration 1term

16 Teachingandexami-

nationlanguage

English

17 Recommendedrea-ding

Thenecessaryliterature,consistingoforiginalandreviewarticleswillbesuppliedbythelecturers.

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1830-SeminarModuleA3.1:MolecularOncology1 Modulename A3.1–MolecularOncology(2490) 5ECTS

2 Courses/lectures S:(2SWS)MandatoryAttendance

3 Lecturers Prof.Dr.J.Behrens,Prof.Dr.T.Brabletz,Prof.Dr.M.Stürzl,Prof.Dr.A.Boßerhoff

4 Modulecoordinator Prof.Dr.J.Behrens

5 Contents

Thestudentspresentanddiscussbasicprinciplesofmolecularoncologyandtranslationalaspectsusingselectedkeypublicationsfromscientificjournals.Theseminarcoversthefollowingaspects:

• oncogenesandtumorsuppressorgenes• oncogenicsignalingpathways• moleculartherapies• animalmodels• molecularclassificationanddiagnosis• tumormicroenvironment• angiogenesis• tumorimmunology

6 Learningobjectivesandskills

Thestudents

• obtainprofoundsubject-specificknowledgeandsubstantialexpertiseinunderstandingmolecularmechanismsoftumordevelopmentandpro-

gression.• obtainskillsforacriticalanalysisandinterpretationofscientificdata.• read,present,analyzeandevaluatecurrentprimaryliterature.• learnthedesignofexperimentalstrategiesandtechniquessuitedtoan-

swerscientificquestionsandpresenttheirsolutionsinoralandwrittenform.

• traintheirabilityfordiscussionandteamworkbyworkinginsmallgroups.

• giveandreceivecriticalfeedbacktoandfromfellowstudent

7 Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine

8 Integrationincurricu-lum

Electivecompulsorymodule,3rdsemester

9

Modulecompatibility M.Sc.MolecularMedicine

10 Methodofexamina-tion

Portfolio:presentation30min(24901)andwrittenexam90min(24902)

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11 Gradingprocedure Gradeofthewrittenexam

12 Modulefrequency Annuallyinthewinterterm

13 WResitexamination Twice

14 Workload Classtime30hStudytime:120h

15 Moduleduration 1term

16 Teachingandexami-

nationlanguage

English

17 Recommendedrea-ding

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1830-SeminarModuleA3.2:CurrentConceptsofImmunology1 Modulename A3.2–CurrentConceptsofImmunology(2495) 5ECTS

2 Courses/lectures S:Immunology(2SWS)MandatoryAttendance

3 Lecturers Prof.Dr.H.-M.Jäck,PDDr.D.Mielenz,Dr.W.Schuh,Dr.J.Wittmann

4 Modulecoordinator Prof.Dr.H.-M.Jäck

5 Contents Thestudentspresentanddiscussimportantphysiologicandpathologicprocessesinbasicandclinicalimmunologyusingselectedkeypublicationsfromscientificjournals.Inaninteractiveround-tableformat,eachstudentwilldeveloptogetherwiththeclassthehypothesis,theexperimentalset-up,thekey-experiment(s)andtheoveralltake-homemessageoftherespectivepublication.

6 Learningobjectivesandskills

Thestudents

• obtainprofoundsubject-specificknowledgeinmolecular,cellularand

clinicalimmunology.• obtainskillsforacriticalanalysisandinterpretationofscientificdata.• read,present,analyzeandevaluatecurrentprimaryliterature.• learnthedesignofexperimentalstrategiesandtechniquessuitedtoan-

swerscientificquestionsandpresenttheirsolutionsinoralandwrittenform.

• traintheirabilityfordiscussionandteamworkbyworkinginsmallgroups.

• giveandreceivecriticalfeedbacktoandfromfellowstudents.

7 Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine

8 Integrationincurricu-

lum

Electivecompulsorymodule,3rdsemester

9

Modulecompatibility MScMolecularMedicineMScCell-undMolecularBiology(DepartmentBiology)MScLifeScienceEngineering(SchoolofEngineering)

10 Methodofexamina-tion

Presentation(24951)andmoderationoftheround-tablediscussion(24952)

11 Gradingprocedure Gradeofthemoderation

12 Modulefrequency Annuallyinthewintersemester

13 WResitexamination Twice

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14 Workload Classtime:30h

Studytime:120h

15 Moduleduration 1term

16 Teachingandexami-nationlanguage

English

17 Recommendedrea-

ding

Janeway'sImmunobiology,GarlandScience,newestedition

Immunology,Kuby,W.H.Freeman,newesteditionRoitt'sEssentialImmunology,Wiley-Blackwell,newestedition

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1830-SeminarModuleA3.3:AnimalModelsinBiomedicalResearch1 Modulename A3.3–AnimalModelsinBiomedicalResearch(2499) 5ECTS

2 Courses/lectures S:(2SWS)MandatoryAttendance

3 Lecturers Prof.Dr.S.v.Hörsten,Prof.Dr.T.Bäuerleandothers

4 Modulecoordinator Prof.Dr.S.v.Hörsten

5 Contents

Thestudentsreviewpresentconceptsinclassification,epidemiology,pathophysiologyandtreatmentofthefollowingmajordiseasesenti-ties:cancer,neurodegenerativedisorders,allergies,autoimmunedis-eases,andmetabolicdisorders.Subsequently,specificdiseasesand/orpathomechanismsarebroughtintofocusandtheirtranslationintoacorrespondinganimalmodelisfurtherelaboratedusingselectedkeypublicationsfromscientificjournals.Theseminarcoverstheapplicationofanimalmodelsincludingzebraf-ish,mice,ratsandlargermammals,fortheinvestigationofdiseasesandtherapeuticapproachesinareassuchas:

• Neoplasiawithfocusonmetastasis• NeurodegenerationincludingAlzheimer´s,Parkinson´s,and

Huntington´sdisease• Allergyincludingasthmaandatopicdermatitis• Autoimmunitywithspecificreferencetomultiplesclerosis• DiabeteswithfocusonTypeIIdiabetes• Specialemphasiswillbegiventosystemsinteractionsaswell

aslimitationsofanimalmodelsincludingbutnotlimitedtotheirstandardization,suitability,andnature-nurturederivedaspectsindiseasesandtheirmodels

6 Learningobjectives

andskills

Thestudents

• obtainprofoundsubject-specificknowledgeinanimaltestingandmodelbasedbiomedicalresearchapproaches.

• obtainskillsforacriticalanalysisandinterpretationofscientificdata.

• read,presentandanalyzecurrentprimaryscientificliterature.• independentlydevelophypothesisandresearchstrategiesand

presenttheirsolutionsinoralandwrittenform.• traintheirabilityfordiscussionandteamworkbyworkingin

smallgroups.• giveandreceivecriticalfeedbacktoandfromfellowstudents.

7 Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine

8 Integrationincurricu-

lum

Electivecompulsorymodule,3rdsemester

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9

Modulecompatibility M.Sc.MolecularMedicine

10 Methodofexamina-

tion

Presentation30min(24991)andtermpaper15-20pages(24992)

11 Gradingprocedure Gradeofthetermpaper

12 Modulefrequency Annuallyinthewinterterm

13 WResitexamination Twice

14 Workload Classtime:30h

Studytime:120h

15 Moduleduration 1term

16 Teachingandexami-nationlanguage

English

17 Recommendedrea-ding

Willbedeterminedindividuallyeachsemester.

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1835-ElectiveModule1 Modulename ElectiveModule 5ECTS

2 Courses/lectures Dependsonchosenmodule

3 Lecturers Dependsonchosenmodule

4 Modulecoordinator Dependsonchosenmodule

5 Contents

ThestudentschoosefromthecoursesofferedatFAU• keyqualifications• modulesfromotherbachelor’sandmaster’sprograms,dependingon

availability• seminarsofferedbythemaster’sprogram

Thekeyqualificationsarefaculty-independentcourseoffersthatarenotrelatedtospecificsubjects,e.g.languages,communicationalandpresentationalskills.Modulesfromotherbachelor’sandmaster’sprogramsthatarenotlistedaskeyqualificationscanonlybechosenwithpermissionfromthemodulecoordinator.ElectivemodulesinmolecularmedicineAdditionalseminarsfromtheelectivecompulsorypartofthemaster’sprograminmolecularmedicinedependonavailability.Additionalelectivemodulesof-feredbythemaster’sprogramarelistedinthemodulemanual.Additionalre-searchmodulesorinternshipsneedtheapprovalofthestudyboard.

6 Learningobjectivesandskills

Thestudents

• cangaininsightintodiverseacademictopics• canacquiresoftskillsthatpromotetheiremployability

• canbroadentheirgeneraleducation• cangainexpertiseinspecificsubjects

7 Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine

8 Integrationincurricu-lum

Electivemodule,1stsemester

9

Modulecompatibility M.Sc.MolecularMedicine

10 Methodofexamina-

tion

Dependonchosenmodule

11 Gradingprocedure Pass/fail

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12 Modulefrequency Everysemester

13 WResitexamination Twice

14 Workload Dependsonchosenmodule

15 Moduleduration 1term

16 Teachingandexami-nationlanguage

Dependsonchosenmodule

17 Recommendedrea-

ding

Dependsonchosenmodule

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2425-ProjectDevelopment1 Modulename 2425-ProjectDevelopment 10ECTS

2 Courses/lectures

P:laboratorycourse(6SWS)T:JournalClub(1SWS)

3 Lecturers Alllecturersofthemaster’sprogram

4 Modulecoordinator Prof.Dr.A.Boßerhoff

5 Contents

Laboratorytraininganddevelopmentofaresearchprojectinpreparationofthemaster’sthesis.Themodulehasamaximumdurationof6weeksandiscom-posedof:

• atutorial,inwhichthestudentandtheadvisordiscusspossibilitiesofaresearchprojectbasedonthecurrentliterature

• laboratorytrainingforthecollectionofpreliminarydata• writingandpresentationofaresearchproposal

6 Learningtargetsandskills

Thestudents

• gaininsightintoaresearchtopicoftheirchoiceandindependentlystudythecurrentliterature

• workandintegratethemselvesinestablishedresearchgroups• applytherulesofgoodscientificpracticetoexperimentation,documen-

tationanddataanalysis

• utilizemodernexperimentaltechniquestocollectscientificdataandcriticallyinterprettheirresults

• evaluatetheirdata,comparethemtopublishedresultsanddiscusstheir

findingswiththeadvisor(s)andtheresearchgroup• developaresearchplanforasixmonthsmaster’sproject

7 Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine

8 Integrationincurricu-lum

Electivecompulsorymodule,3rdsemester

9

Modulecompatibility M.Sc.MolecularMedicine

10 Methodofexamina-tion

Projectplan5-10pages(24251)

Proposedprojectandhypothesis(10lines)Background(1/2-1page)Preliminarydatafromthelaboratorycourse(2-4pages)

Timetableforthemaster’sproject(1/2page)

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Costcalculation(1page)

References(max.10)

Font:Arial,size:11pt,spacing:1,5x,legendsbeneathimagesortablesin9pt

11 Gradingprocedure Gradeoftheprojectplan

12 Modulefrequency Eachsemester

13 WResitexamination Twice

14 Workload Classtimeandstudytime:300h

15 Moduleduration 1term

16 Teachingandexami-

nationlanguage

English

17 Recommendedrea-ding

Individuallydefinedbytheadvisor

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43

Area3–ElectiveCompulsoryModulesB

CurricularCategoriesandModuleNames ECTS Semester

Area3–ElectiveCompulsoryModulesB 25 Areagrade

ExternalModule 25 2.+3. Graded

Alternativepossibility:choiceofmodulesfor25ECTSfromthefollowing

ExternalModulesfor10,15or20ECTS 10,15

or20

Graded

ResearchModulesatFAUfor10ECTS 10 Graded

ElectiveModule 5 Pass/fail

Theareagradeiscalculatedastheaverageofthemodulesweightedbythemodules’ECTSpoints.Thearea3gradecontributesapprox.21%tothefinalmaster’sgrade(25/120ECTS).

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1850-B1-ExternalModule1 Modulename B1–ExternalModule(2610) 25ECTS

2 Courses/lectures

P:5monthscoursesorplacementatanexternalresearchinstitutionorcompany

3 Lecturers AdvisorsoftheMolecularMedicineprogram

4 Modulecoordinator Headoftheauditcommittee

5 Contents

Thestudentcan• followacoursecurriculumfromadifferentuniversityor• doalaboratorycourseatanationalorinternationalresearchinstituteor• doacompany/industryplacement

Allcoursesandplacementsmustbeinagreementwiththestudyboardbeforeexecution(learningagreement)

6 Learningobjectives

andskills

Thestudents• cangaininsightintointernationalandindustrialresearchenvironments• canacquirespecializedknowledgeandpracticalskillsinaresearchfield

oftheirchoice• independentlyorganizethecurriculum• copewithunfamiliarsituations• canimprovetheirlanguageskills• presenttheirworkinwrittenform

7 Prerequisite EnrollmentintheM.Sc.programofMolecularMedicine

8 Integrationincurricu-lum

Electivecompulsorymodule,2ndand3rdsemester

9 Modulecompatibility M.Sc.MolecularMedicine

10 Methodofexamina-

tion

Dependsonchosencontent

Placement/laboratorycourse:presentation30minpass/fail(26101)andproto-col,usually20-30pages(graded)(26102)

Ifthestudentfollowsacoursecurriculumatadifferentuniversitythemodules,ECTSandgradeswillbetransferred.

11 Gradingprocedure Gradeoftheexamination(s)

12 Modulefrequency Annually

13 WResitexamination Twice

14 Workload 750h

15 Moduleduration 2terms

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16 Teachingandexami-

nationlanguage

Dependsonchoice

17 Recommendedrea-ding

Dependsonchoice

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B2-ExternalModule1860/1870/18801 Modulename B2.1–ExternalModule(2615)

B2.2–ExternalModule(2620)B2.3–ExternalModule(2625)

20ECTS15ECTS10ECTS

2 Courses/lectures

B2.14monthscoursesorplacementB2.23monthscoursesorplacementB2.32monthscoursesorplacementatanexternalresearchinstitutionorcompany

3 Lecturers AdvisorsoftheMolecularMedicineprogram

4 Modulecoordinator Headoftheauditcommittee

5 Contents

Thestudentcan• followacoursecurriculumfromadifferentuniversityor• doalaboratorycourseatanationalorinternationalresearchinstituteor• doacompanyplacement

Allcoursesandplacementsmustbeinagreementwiththestudyboardbeforeexecution(learningagreement).

6 Learningtargetsandskills

Thestudents• cangaininsightintointernationalandindustrialresearchenvironments• canacquirespecializedknowledgeandpracticalskillsinaresearchfield

oftheirchoice• independentlyorganizethecurriculum• copewithunfamiliarsituations• canimprovetheirlanguageskills• presenttheirworkinwrittenform

7 u

ire

Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine

8 Integrationincurricu-lum

Electivecompulsorymodule,2ndand3rdsemester

9

Modulecompatibility M.Sc.MolecularMedicine

10 Methodofexamina-tion

DependsonchosencontentInternship/laboratorycourse:presentation30min(pass/fail)andprotocol,usu-

ally20-30pages(graded)Ifthestudentfollowsacoursecurriculumatadifferentuniversity,themodules,

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ECTSandgradeswillbetransferred.

11 Gradingprocedure Gradeoftheexamination(s)

12 Modulefrequency

13 WResitexamination Twice

14 Workload B2.1:600hB2.2:450h

B2.3:300h

15 Moduleduration 1-2terms

16 Teachingandexami-nationlanguage

Dependsonchoice

17 Recommendedrea-ding

Dependsonchoice

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B3-LaboratoryResearchModule1 Modulename B3–LaboratoryResearchModule(2630,2635) 10ECTS

2 Courses/lectures

P:2monthslaboratorycourseatFAU

3 Lecturers AdvisorsoftheMolecularMedicineprogram

4 Modulecoordinator Headoftheauditcommittee

5 Contents

ThestudentsworkonabiomedicalresearchprojectinaFAUlaboratoryoftheirchoice.Theyindependentlystudytherelatedliterature,plan,executeanddocumentexperimentsandwritearesearchprotocol.Thelaboratorytimecanalsobesplitbetweentworesearchgroups(collaborativesupervision;oneprotocol).

6 Learningtargetsand

skills

Thestudents• acquirespecializedknowledgeinaresearchfieldoftheirchoice• integrateintoexistingresearchgroups• followtherulesofgoodscientificpractice• plan,performanddocumentresearchexperiments• utilizemodernexperimentaltechniques• presenttheirworkinwrittenform

7 uire

Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine

8 Integrationincurricu-lum

Electivecompulsorymodule,2ndand3rdsemester

9

Modulecompatibility M.Sc.MolecularMedicine

10 Methodofexamina-

tion

Presentation30minandprotocolofusually20-30pages

11 Gradingprocedure Gradeoftheprotocol

12 Modulefrequency Eachsemester

13 WResitexamination Twice

14 Workload 300h

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15 Moduleduration 1term

16 Teachingandexami-

nationlanguage

Dependsonchoice

17 Recommendedrea-ding

Dependsonchoice

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Area4–Master’sThesis

CurricularCategoriesandModuleNames ECTS Semester

Area4–Master‘sThesis 30 Areagrade

Master’sThesis 25 4. Graded

Master’sColloquium 5 4. Graded

Theareagradeiscalculatedastheaverageofthemodulesweightedbythemodules’ECTSpoints.Thearea4gradecontributes25%tothefinalmaster’sgrade(30/120ECTS).

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Master’sThesis1 Modulename Master‘sThesis 25ECTS

2 Courses/lectures

Researchproject

3 Lecturers Thesisadvisorsoftheprogram

4 Modulecoordinator Headoftheauditcommittee

5 Contents Independentinvestigationofanup-to-dateresearchquestionfromthefieldofmolecularmedicine:laboratorywork,dataanalysisandwrittenpresentation.Generally,thestudentsworkontheresearchplansthattheydevisedinthemodule“ProjectDevelopment”.Achangeoftopicorlaboratorymustbeap-provedbythestudyboard.

6 Learningtargetsand

skills

Thestudents

• gaintheabilitytoworkonacurrentscientificproblemoveraperiodof

5-6months• applytherulesofgoodscientificpracticetoexperimentation,documen-

tationanddataanalysis

• broadentheirskillstoplan,structureandworkoncomplexproblems• acquiresubjectspecificknowledgeinthechosenresearchfield• planandmanagetheirprojectwithinthegiventimeframe

• developconceptsandapproachestosolveascientificproblem• criticallyanalyzeandreflectontheories,concepts,terminology,limits

andspecificfeaturesoftheirchosentopic

• chooseappropriatescientificmethodsandapplythemtonewandinter-disciplinarycontents

• presentthedatainascientificallycorrectform

• present,interpretanddefendsubjectspecificcontentsinaclear,audi-ence-orientedform

7 Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine

Thestudentmusthaveacquired80ECTScreditpointsfromthecurriculumprior

tostartingthemaster’sproject

8 Integrationincurricu-lum

4thsemester

Attention:closetimingwiththemodule“Master’scolloquium”

9

Modulecompatibility M.Sc.MolekulareMedizin

10 Methodofexamina- WrittenThesis

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tion Writtenelaborationinformofascientificmanuscript.Itdescribesthescientific

findingsaswellasthewayleadingtothesefindings.Itcontainsjustificationsfordecisionsregardingchosenmethodsforthethesisanddiscardedalternatives.Thestudent’sownsubstantialcontributiontotheachievedresultshastobeevi-

dent.Formoreinformation,refertoNo.18.

11 Gradingprocedure Gradeofthewrittenthesis(arithmeticmeansofthetwoexpertreports)

12 Modulefrequency Eachsemester

13 WResitexamination once

14 Workload Thethesishastobepreparedwithin6months

15 Moduleduration 1Semester

16 Teachingandexami-

nationlanguage

English

17 Recommendedrea-ding

Dependsonthesissubject

18 Additionalinformati-

on

-Themaster’sthesishastoberegisteredinAprilforthesummertermandin

Octoberforthewintertermusingtheofficialformissuedbythestudyboard.

-Thetimelimitforthepreparationofthemaster’sthesisis6months.Thethe-sisadvisorsareaskedtopayattentiontoensureanadequateextentofthetreatedsubject.

-Anextensionuptoonemonthispossibleunderwellfoundedcircumstances.-Normally,thethesiswillbeperformedinthesamelabasthemodule“ProjectDevelopment”onthesubjectofthestudent’sprojectproposal.Achangeof

laboratoryorsubjectmustbeapprovedbythestudyboard.-Itisrecommendedtoinvestfivemonthsintotheexperimentalworkandonemonthintowritingthethesis.

ThethesismustbewritteninEnglish.ItcanonlybewritteninGermanuponapprovalofthestudyboard.Itmustadheretothefollowingformalrequire-ments:

-Font:Arial,size:11pt,spacing:1,5x,legendsbeneathimagesortablesin9pt.-Thethesishastheformofascientificpublication,includinganindex,alistofabbreviations,andthechapters1.AbstractsinEnglishandGerman,2.Introduc-

tion,3.MaterialandMethods,4.Results,5.Discussion,6.FuturePerspectivesand7.References.

-TheAbstractshouldnotexceed400words(1page).Thewholethesismaynotexceed40.000wordsandshouldgenerallybeshorterthan100pages.Thethesismustincludeastatement,thatnootherthanthestatedsourcesand

aidswereused.-Thethesismustbesubmittedontimetotheadvisor(s)intwoprintedversionsandanelectronicversion(PDF).Thesubmissionhastobedocumentedonthe

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officialformissuedbythestudyboard.

-Bothadvisorsprovideindependentreports(1-2pages)withinonemonthaftersubmission.Thegradingadheresto§18Prüfungsordnung.

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Master‘sColloquium1 Modulename Master‘sColloquium 5ECTS

2 Courses/lectures Colloquium

3 Lecturers Thesisadvisorsoftheprogram

4 Modulecoordinator Headoftheauditcommittee

5 Contents Presentationofthemaster’sthesisintheframeworkofanall-daycolloquium.Thestudentspresenttheirworkinaseminar,inwhichthescientificqualityandthescientificindependenceofhis/herachievementsareevaluated.Thethesisadvisorsevaluatethestudents’knowledgeintheresearchsubjectandrelatedsubjects.

6 Learningtargetsandskills

Thestudents

• presenttheirdatainascientificallycorrectform• present,interpretanddefendtheirresearchresultsinaclear,audience-

orientedform

• comparetheirresultstopublisheddata• transfersubject-specificknowledgetootherareasofbiomedicine

7 Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine

8 Integrationincurricu-lum

4thsemester

9 Modulecompatibility M.Sc.MolekulareMedizin

10 Methodofexamina-tion

Oralexam:presentation,discussionandopenquestions,approx.15min

11 Gradingprocedure Gradeoftheoralexam

12 Modulefrequency Eachsemester;

summerterm:ColloquiuminSeptemberorOctober

winterterm:Presentationinpresenceoftheexaminersboard

13 WResitexamination once

14 Workload 1-2dayscolloquiumandpreparation

15 Moduleduration 1Semester

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16 Teachingandexami-

nationlanguage

English

17 Recommendedrea-ding


Recommended