FRIEDRICH-ALEXANDER UNIVERSITÄT ERLANGEN-NÜRNBERG
MEDIZINISCHE FAKULTÄT
Modulehandbook
ofthemaster’sprogramin
MolecularMedicine
(MasterofScience)
(version10/2018)
2
Index
Index........................................................................................................................................................2
GeneralInformation................................................................................................................................4
ExaminationRegulations.........................................................................................................................4
AdvisorsintheMolecularMedicineMasterprogram ............................................................................4
Curriculum...............................................................................................................................................6
Area1-CompulsoryModules.................................................................................................................7
AdvancedLecturesinMolecularMedicine1 ..........................................................................................8
ArchitectureofBiopolymers .................................................................................................................11
LaboratoryAnimalScienceandBiologicalSafety..................................................................................13
AdvancedLecturesinMolecularMedicine2 ........................................................................................15
ResearchDesign ....................................................................................................................................18
Area2–ElectiveCompulsoryModulesA ..............................................................................................20
SeminarModuleA1.1:MolecularGeneticsandGenomics...................................................................21
SeminarModuleA1.2:MolecularMicrobiologyandImmunologyofInfection....................................23
SeminarModuleA1.3:MolecularImaging............................................................................................25
SeminarModuleA2.1:MolecularNeuroscience ...................................................................................27
SeminarModuleA2.2:EssentialConceptsinModernVirology............................................................29
SeminarModuleA2.3:Molecularandtranslationalconceptsofcardiacandrenaldisease ................31
SeminarModuleA3.1:MolecularOncology .........................................................................................33
SeminarModuleA3.2:CurrentConceptsofImmunology ....................................................................35
SeminarModuleA3.3:AnimalModelsinBiomedicalResearch ...........................................................37
ElectiveModule.....................................................................................................................................39
ProjectDevelopment ............................................................................................................................41
Area3–ElectiveCompulsoryModulesB..............................................................................................43
B1-ExternalModule.............................................................................................................................44
B2-ExternalModule.............................................................................................................................46
B3-LaboratoryResearchModule.........................................................................................................48
Area4–Master’sThesis .......................................................................................................................50
Master’sThesis......................................................................................................................................51
Master‘sColloquium .............................................................................................................................54
3
4
GeneralInformationThemaster’s program inMolecularMedicine at the FAU Erlangen-Nuremberg starts in thewinter
term.TheusualperiodforcompletingtheM.Sc.istwoyears(4semesters),afterwhichaPh.D.pro-gram can be started. The master’s program is based on the bachelor’s program “MolekulareMedizin”atFAUandprovidesanadvancededucationwiththegoalofpreparingstudentsforacareer
inbiomedicalresearch.Allcoursesofthemaster’sprogramaregiveninEnglish.
Toenterthemaster’sprogram,applicantsmusthavecompletedabachelor’sdegreewithhighaca-demicstandingfromarecognizeduniversity.
ApplicantsapplyonlinethroughthemasterapplicationportaloftheFAU: https://www.fau.eu/study/prospective-students/application-and-enrolment/applying-for-masters-
degree-programmes/
Themaster’sprogramincludescompulsory,electivecompulsoryandelectivemodules.Themaster’sthesisiscompletedduringthefourthsemester.Allmodulesaddupto120ECTScreditpoints.
Anexternalstayofuptosixmonthsduration–preferentiallyabroad-issuggestedforallstudents.
ExaminationRegulationshttps://www.fau.de/universitaet/rechtsgrundlagen/pruefungsordnungen/
AdvisorsintheMolecularMedicinemaster’sprogramStudents’DeanfortheprograminMolecularMedicineandHeadoftheauditcommitteeProf.Dr.AnjaBoßerhoffLehrstuhlfürBiochemieundMolekulareMedizin
Friedrich-Alexander-UniversitätErlangen-NürnbergFahrstr.17,91054Erlangen,Office/Room03.036Tel.:091318524190
mail:[email protected]
CoordinatorandadvisorforthestudyprograminMolecularMedicineDr.SimoneReiprichDean’sofficeoftheFacultyofMedicine
Friedrich-Alexander-UniversitätErlangen-NürnbergKrankenhausstr.12,91054Erlangen,Office/RoomG02.231Tel.:091318524687
mail:[email protected]
5
Abbreviations
L Lecture
T TutorialS SeminarP PracticalTraining
FAU Friedrich-Alexander-UniversityErlangen-Nürnberg
6
Curriculum
CurricularCategoriesandModuleNames ECTS Semester
Area1–CompulsoryModules 35
AdvancedLecturesinMolecularMedicine1 10 1.
LaboratoryAnimalScienceandBiologicalSafety 5 1.
ArchitectureofBiopolymers 5 1.
AdvancedLecturesinMolecularMedicine2 10 2.
ResearchDesign 5 2.
Area2–ElectiveCompulsoryModulesA 30
ElectiveModule 5 1.
ElectiveCompulsorySeminarModule1 5 1.
ElectiveCompulsorySeminarModule2 5 2.
ElectiveCompulsorySeminarModule3 5 3.
ProjectDevelopment 10 3.
Area3–ElectiveCompulsoryModulesB 25
ExternalModule/s,LaboratoryResearchModules 25 2.+3.
Area4–Master‘sThesis 30
Master’sThesis 25 4.
Master’sColloquium 5 4.
120
7
Area1-CompulsoryModules
CurricularCategoryandModuleNames ECTS Semester
Area1-CompulsoryModules 35 Areagrade
AdvancedLecturesinMolecularMedicine1 10 1. Graded
LaboratoryAnimalScienceandBiologicalSafety 5 1. Pass/fail
ArchitectureofBiopolymers 5 1. Graded
AdvancedLecturesinMolecularMedicine2 10 2. Graded
ResearchDesign 5 2. Graded
Theareagradeiscalculatedastheaverageofthemodulesweightedbythemodules’ECTSpoints.Thearea1gradecontributesapprox.29%tothefinalmaster’sgrade(35/120ECTS).
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea1-CompulsoryModules
8
AdvancedLecturesinMolecularMedicine11 Modulename 2430-AdvancedLecturesinMolecularMedicine1 10ECTS
2 Courses/lectures
-V:Immunology(2SWS)-V:MolecularNeuroscience(2SWS)-V:MolecularImaging(2SWS)
3 Lecturers Prof.Dr.C.Bogdan,Prof.Dr.D.Vöhringer,Prof.Dr.K.Prof.Dr.G.Kröncke,Prof.Dr.D.Dudziak,,Prof.Dr.C.Alzheimer,Prof.Dr.R.Enz,Prof.Dr.J.Winkler,Prof.Dr.D.C.Lie,Prof.Dr.T.Bäuerleandothers
4 Modulecoordinator Prof.Dr.Enz
Lecturecoordinators:Prof.Bogdan(Immunology),Prof.Enz(Neuroscience),Prof.Lie(Imaging)
5 Contents
Lecture:ImmunologyMechanisms,modelsandconcepts
• Evolution,components,functionanddysfunctionoftheimmunesystem• Anti-infectiousimmuneresponse:innate,TandBcell-mediatedimmu-
nity• Terminationoftheimmuneresponse,resolutionofinflammationand
tissuerepair• Tumorimmunology
Medicalaspects• Allergies,autoimmunity,chronicinflammatoryandautoinflammatory
diseases,immunodeficiencies,graftvs.hostdisease• Immunotherapy,antibodiesandvaccination
SpecifictechniquesandmethodsinimmunologyLecture:MolecularNeuroscienceMechanisms,modelsandconcepts
• Neurocytologyandsynapses
• Learning,memory,dementiaandsleep• Sensorysystems:Pain,Hearing,Vision
• Plasticityinthecentralnervoussystem• Braindevelopment
Medicalaspects
• Neurodegenerativediseasesandstroke• Psychiatricdiseases
Specifictechniquesandmethodsinneuroscience
Lecture:MolecularImagingMechanisms,modelsandconceptsPrinciplesofimagingandmanipulationofcell-biologicalundmolecularprocesses
MedicalaspectsPreclinicalmodelsforhumandiseases(CNSDiseases,Oncology)Specifictechniquesandmethodsinmolecularimaging
• opticalimaging
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea1-CompulsoryModules
9
• transgenicreportersforopticalimaging• MagneticResonanceImaging• SPECTundPET• optogenetics
6 Learningobjectivesandskills
Thestudents
• obtainprofoundknowledgeintheabovedescribedcontents.
• understandprinciplemolecularandcellularmechanismsandtheirinter-playinthenervousandimmunesystems.
• understandbasicandstate-of-the-artconceptsinimagingofbiomedi-callyrelevantmolecularandcellbiologicalprocesses.
• transferobtainedtheoreticalandmethodologicalknowledgetoresearch
projectsandtoclinicalsettingsincludingmoleculartherapiesanddiag-nostics.
7 Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine
8 Integrationincurricu-lum
Compulsorymodule,1stsemester
9 Modulecompatibility M.Sc.MolecularMedicine
10 Methodofexamina-
tion
Writtenexam,180min,openquestionsandmultiplechoice(24301)
11 Gradingprocedure Gradeofthewrittenexam
12 Modulefrequency Annuallyinthewinterterm
13 WResitexamination Twice
14 Workload Classtime:90hStudytime:210h
15 Moduleduration 1term
16 Teachingandexami-nationlanguage
English
17 Recommendedrea-ding
ImmunologyCellularandMolecularImmunology,eds.Abbas,LichtmanandPillai,Elsevier-
Saunders,newestedition;Janeway´sImmunobiology,eds.Murphy,TraversandWalport,GarlandScience,newstedition
NeurosciencePrinciplesinNeuralScience,Ed.Kandel,Schwartz,Jessel,McGrawHill
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea1-CompulsoryModules
10
BasicNeurochemistry,Ed.Siegel,Albers,Brady,Price,AcademicPress
newesteditions
ImagingWeisslederetal.,MolecularImaging,People’sMedicalPublishingHouse,newestedition
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea1-CompulsoryModules
11
ArchitectureofBiopolymers1 Modulename 2440-ArchitectureofBiopolymers 5ECTS
2 Courses/lectures
S:ArchitectureofBiopolymers(2SWS)MandatoryAttendanceT:Computer-basedtutorialtoArchitectureofBiopolymers(2SWS)
3 Lecturers Prof.Dr.H.Stichtandothers
4 Modulecoordinator Prof.Dr.H.Sticht
5 Contents
Mechanisms,modelsandconcepts• Principlesofproteinstructureanditsroleforproteinfunction.• Alterationsofproteinstructureandemergenceofdisease.• Elementsofproteinstructure• Effectofmutationsonproteinstabilityandfunction
Specifictechniquesandmethodsinstructuralbiochemistrywithmedicalaspects• Computationalanalysisofbiomolecularstructuresandofdisease-
associatedproteinmutations.• Methodsforstructuredetermination• Proteindatabasesandtheirrespectivedataformats• Methodsforinsilicodataanalysis• Structuresofmedicallyimportantproteinclasses(e.g.kinases,prote-
ases,nucleicacidbinding,ortransmembraneproteins)• Linearsequencemotifsandproteininteractiondomains• Post-translationalmodifications• Protein(mis-)foldingandaggregation• Proteindesign• Visualizationofmolecularstructures• Analysisofinteractingmolecularsurfaces
6 Learningobjectives
andskills
Thestudents
• gaininsightintothestructuralprinciplesofbiopolymersandtheirimpli-cationsonfunction
• acquireprofoundandhands-onknowledgeofimportantconcepts,data-bases,tools,andmethodsinstructuralandcomputationalbiology
• areabletodescribeandtoapplythesemethodstorelatedproblemsinthefieldofstructuralbiology
• presentandcriticallydiscussscientificfindingsinseminartalks• gainexperiencewithatoolsetofcomputationalmethodsandvisualiza-
tionprogramsthattheycanapplytotheirfurtherstudiesandresearchprojects
7 Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine
8 Integrationincurricu-lum
Compulsorymodule,1stsemester
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea1-CompulsoryModules
12
9
Modulecompatibility M.Sc.MolecularMedicine
10 Methodofexamina-
tion
Portfolio
1.Writtenexam,60min,multiplechoicequestions(24402)2.Presentationwithdiscussion(approx.30min)(24401)
11 Gradingprocedure Gradeofthewrittenexam
12 Modulefrequency Annuallyinthewinterterm
13 WResitexamination Twice
14 Workload Classtime:60hStudytime:90h
15 Moduleduration 1term
16 Teachingandexami-nationlanguage
English
17 Recommendedrea-
ding
Literatureprovidedontheinstitute’shomepage:
http://www.biochem.uni-erlangen.de/studium/index.php„DownloadsBiopolymers“(passwordneeded)
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea1-CompulsoryModules
13
LaboratoryAnimalScienceandBiologicalSafety1 Modulename 2450–
LaboratoryAnimalScienceandBiologicalSafety5ECTS
2 Courses/lectures
-L:LaboratoryAnimalScienceincludingWelfareforpersonscarryingoutanimalexperiments(1SWS)MandatoryAttendance(20hre-quired)-P:Animaltechniquesforpersonscarryingoutanimalexperiments(1.5SWS)MandatoryAttendance(20hrequired)-L:BiologicalSafety(1SWS)
3 Lecturers Prof.Dr.S.vonHörsten,Dr.Schwarz,Dr.R.Jurgons,Dr.Schulze-Krebs,Prof.Dr.A.Boßerhoffandothers
4 Modulecoordinator Prof.S.vonHörsten
5 Contents
AnimalCareandProtection• Relevantlegalprovisions(nationalandinternational)• Ethicalaspectsofworkingwithlaboratoryanimals• the3Rprinciple:“replace,reduce,refine”• Biologyandhousingofthemostimportantlaboratoryanimalspecies• Physiologicalrequirements• Diseasesoflaboratoryanimals,zoonoses,hygieneinanimalhousing• Assessmentofstressandmeasuresfortheavoidanceofpainandsuffer-
ance• Planningandtheoreticalexecutionofanimalexperiments• Behavioroflaboratoryanimalsandspecies-appropriatehandling• Administrationofsubstances• Techniquesofsamplewithdrawal• Killingtechniques• anesthesiology,analgesiaandbasicprinciplesofsurgery
Thestudentsobtainacertificateforpersonscarryingoutanimalexperiments(FELASACategoryB)(“FachkundenachweisnachdenFELASABRichtlinien”).Thecontents,durationandrealizationofthiscourseadheretoofficialregulationsandFELASArecommendations.Theattendanceofthelecture(20h)andpracticalexercises(20h)arethereforemandatory. BiologicalSafety
• Riskpotentialofworkingwithgeneticallymodifiedorganisms(GMO)• RiskpotentialofGMOsrelease• Legalprovisionsandsecuritymeasuresforlaboratoriesanddivisions
workingwithGMOs• Healthandsafetymeasures
Studentscanobtainthe„FachkundenachweisProjektleiterfürdieBiologischeSicherheitnach§15undS17GenTSV“.
6 Learningobjectives
andskills
Thestudents
• knowandunderstandthelegalprerequisitesforworkingwithlaboratoryanimalsandgeneticallymodifiedorganisms
• reflecttheethicalaspectsofanimaltestingandgeneticengineering• becomeacquaintedandtrainedinanimalhandlingandstandardlabora-
toryanimaltechniques(mouse,rat,largeanimal)
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea1-CompulsoryModules
14
7 Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine
8 Integrationincurricu-
lum
Compulsorymodule,1stsemester
9
Modulecompatibility M.Sc.MolecularMedicine
10 Methodofexamina-tion
Practicalexam120min(24501)
11 Gradingprocedure Pass/fail
12 Modulefrequency Annuallyinthewinterterm
13 WResitexamination Twice
14 Workload Classtime:50hStudytime:110h
15 Moduleduration 1term
16 Teachingandexami-
nationlanguage
English
17 Recommendedrea-ding
Script„AnimalCareandProtection“GrundlagenderVersuchstierkunde,vanZutphen,Baumans,Beynen,neuesteAuflage,GustavFischerISBN3-437-20532-3
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea1-CompulsoryModules
15
AdvancedLecturesinMolecularMedicine21 Modulename 2435-AdvancedLecturesinMolecularMedicine2 10ECTS
2 Courses/lectures
L:MolecularOncology(2SWS)L:MolecularEmbryology(2SWS)L:MolecularGeneticsandSystemsMedicine(2SWS)
3 Lecturers Prof.Dr.J.Behrens,Prof.Dr.A.Boßerhoff,Prof.Dr.T.Brabletz,Prof.Dr.M.Stürzl,Prof.Dr.M.Wegner,Prof.Dr.F.Engel.Prof.Dr.A.Reis,Prof.Dr.A.Winterpacht,Prof.Dr.J.Vera-Gonzalezandothers
4 Modulecoordinator Prof.Dr.M.Wegner
Lecturecoordinators:Prof.Behrens(Oncology),Prof.Wegner(Embryology),
Prof.Reis(GeneticsandSystemsMedicine)
5 Contents
MolecularOncologyMechanisms,modelsandconcepts
• Generaltumorcellbiology• Oncogenesandtumorsuppressorgenes• Oncogenicsignalingpathways• Cellcycleandregulationofcelldeath• Transcriptionandepigenetics• Metabolomicsandcancer• Multisteptumorigenesis• Tumormicroenvironment• Invasionandmetastasis• Genomeintegrity• Conceptoftumorstemcells• Tumorangiogenesisandimmunology• Animalmodelsinoncology
Medicalaspects• Moleculartherapies• Molecularclassification• Moleculardiagnosis• Translationalaspects
SpecifictechniquesandmethodsinmolecularoncologyMolecularEmbryologyMechanisms,modelsandconcepts
• Principlesofhumandevelopment• Developmentalprinciplesofbiomedicallyrelevantmodelorganisms• Intrinsicandextrinsicregulatorypathwaysofdevelopment• EarlyembryonicdevelopmentofC.elegans,D.melanogasterandverte-
brates• Axisformation,germlayerformation,sexdetermination• Mesodermaldevelopment• Ectodermalandneuralcrestdevelopment
Medicalaspects• inbornerrorsofdevelopmentascauseofdisease
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea1-CompulsoryModules
16
• malformationsandsyndromes• pleiotropy
SpecifictechniquesandmethodsinmolecularembryologyMolecularGeneticsandSystemsMedicineMechanisms,modelsandconcepts
• ModulationofpenetranceinMendeliandiseases• Molecularbasisofcomplexdiseases• Epigeneticmechanisms• Gene-andgenomeregulation• Geneticapproachesusinganimalmodels• Statisticalinterpretationoflargedatasets• Quantitativetraitloci• Analysis,reconstructionandmodellingofbiologicalsystemsandnet-
worksMedicalaspects
• geneticandepigeneticchangesunderlyinghumandisease• physiologyandpathophysiologyofgeneticallydeterminedbiological
processesSpecifictechniquesandmethodsinmoleculargeneticsandsystemsmedicine
6 Learningobjectives
andskills
Thestudents
• gainknowledgeintheabovementionedcontents.• Understandbasicandmodernconceptsofbiochemicalsystems,molecu-
larandcellularoncology,molecularembryologyandmoleculargenetics.• gaininsightintothemechanismsunderlyingdevelopmentandselected
developmentaldisorders,tumorbiology,geneticandepigeneticmisregu-lationinselecteddisorders.
• transferobtainedtheoreticalandmethodologicalknowledgetoresearchprojectsandtoclinicalsettingsincludingmoleculartherapiesanddiag-nostics.
• utilizebiostatisticalmethodsandoperatestandardsoftwaretoolsfornetworkanddataanalyses.
• develop,interpret,evaluateanddiscussbiochemicalnetworksandsta-tisticalanalysesofbiologicaldata
7 Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine
8 Integrationincurricu-lum
Compulsorymodule,2ndsemester
9 Modulecompatibility M.Sc.MolecularMedicine
10 Methodofexamina-tion
Writtenexam,180min,openandmultiplechoicequestions(24351)
11 Gradingprocedure Gradeofthewrittenexam
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea1-CompulsoryModules
17
12 Modulefrequency Annuallyinthesummerterm
13 WResitexamination Twice
14 Workload Classtime:90hStudytime:210h
15 Moduleduration 1term
16 Teachingandexami-nationlanguage
English
17 Recommendedrea-
ding
Oncology
RobertA.Weinberg,TheBiologyofCancer,2ndedition,GarlandScience
EmbryologySelectedchaptersfromScottF.Gilbert:DevelopmentalBiology(SinauerPress)or
LewisWolpert:PrinciplesofDevelopment(OxfordUniversityPress),Newesteditions
MolecularGeneticsSelectedchaptersfromTomStrachanandAndrewRead:HumanMolecularGe-
netics(GarlandScience)orTomStrachanetal.:GeneticsandGenomicsinMedi-cine(GarlandScience),newesteditions
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea1-CompulsoryModules
18
ResearchDesign1 Modulename 2445-ResearchDesign 5ECTS
2 Courses/lectures S:ProjectandProposalDesign(3SWS)MandatoryAttendance
3 Lecturers Prof.Dr.Behrens,Prof.Dr.Brabletz,Prof.Dr.Lie,Prof.Dr.Stürzlandothers
4 Modulecoordinator Prof.Dr.Behrens
5 Contents DevelopmentofscientificprojectsGrant/paperwritingstrategiesGoodscientificpractice
6 Learningobjectives
andskills
Thestudents
• areabletoperformliteraturesearchesandtocriticallysummarizethestateoftheart
• applytheobtainedknowledgetogeneratescientifichypotheses• learnhowtodevelopandformulateascientificresearchprogramtotest
thesehypothesesadheringtotherulesofgoodscientificpractice• acquireskillsinscientificwritingofresearchpapers,projectplansand
grants• presentanddiscussprojectproposalsinoralpresentations
7 Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine
8 Integrationincurricu-
lum
Compulsorymodule,2ndsemester
9 Modulecompatibility M.Sc.MolecularMedicine
10 Methodofexamina-tion
Seminarpresentation30min(24451)andtermpaper7-10pages(24452)
11 Gradingprocedure Gradeofthetermpaper
12 Modulefrequency Annuallyinthesummerterm
13 WResitexamination Twice
14 Workload Classtime:45hStudytime:105h
15 Moduleduration 1term
16 Teachingandexami-
nationlanguage
English
17 Recommendedrea- Booklet“SafeguardingGoodScientificPractice”(DFG)
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea1-CompulsoryModules
19
ding
20
Area2–ElectiveCompulsoryModulesA
CurricularCategoryandModuleNames ECTS Semester
Area2–ElectiveCompulsoryModulesA 30 Areagrade
SeminarModule1 5 1. Graded
SeminarModule2 5 2. Graded
SeminarModule3 5 3. Graded
ElectiveModule 5 1. Pass/fail
ProjectDevelopment 10 3. Graded
Theareagradeiscalculatedastheaverageofthemodulesweightedbythemodules’ECTSpoints.
Thearea2gradecontributes25%tothefinalmaster’sgrade(30/120ECTS).
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea2–ElectiveCompulsoryModules
21
1810-SeminarModuleA1.1:MolecularGeneticsandGenomics1 Modulename A1.1–MolecularGeneticsandGenomics(2460) 5ECTS
2 Courses/lectures S:(2SWS)MandatoryAttendance
3 Lecturers Prof.Dr.A.Reis,Prof.Winterpachtandothers
4 Modulecoordinator Prof.Dr.A.Reis
5 Contents
Thestudentspresentanddiscussbasicprinciplesof moleculargeneticsandge-nomicsusingselectedkeypublicationsfromscientificjournals.Theseminarcoversthefollowingaspects:
• Mechanismsofgeneregulation• Genomicarchitectureandphenotypicvariability• Wholegenomesequencingapproachesforunderstandinggeneticvaria-
tion• Molecularbasisofcomplexdiseases• Molecularmechanismsofepigeneticregulationandinheritance• Animalmodelsindissectinggeneticcomponentsofcomplextraits• Interpretationoflargegenomicdatasets
6 Learningobjectives
andskills
Thestudents
• obtainprofoundsubject-specificknowledgeinmoleculargeneticsandgenomics
• obtainskillsforacriticalanalysisandinterpretationofscientificdata.• read,presentandanalyzecurrentprimaryscientificliterature• independentlysolveproblemsinthefieldofmoleculargeneticsandpre-
senttheirsolutionsinoralandwrittenform• traintheirabilityfordiscussionandteamworkbyworkinginsmall
groups• giveandreceivecriticalfeedbacktoandfromfellowstudents
7 Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine
8 Integrationincurricu-
lum
Electivecompulsorymodule,1stsemester
9
Modulecompatibility M.Sc.MolecularMedicine
10 Methodofexamina-tion
Presentation30min(24601)andtermpaper15-20pages(24602)
11 Gradingprocedure Gradeofthetermpaper
12 Modulefrequency Annuallyinthewinterterm
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea2–ElectiveCompulsoryModules
22
13 WResitexamination Twice
14 Workload Classtime30h
Studytime120h
15 Moduleduration 1term
16 Teachingandexami-nationlanguage
English
17 Recommendedrea-
ding
TomStrachanetal.:GeneticsandGenomicsinMedicine(GarlandScience),new-
estedition
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea2–ElectiveCompulsoryModules
23
1810-SeminarModuleA1.2:MolecularMicrobiologyandImmunologyofInfection
1 Modulename A1.2–MolecularMicrobiologyandImmunologyofInfection(2465)
5ECTS
2 Courses/lectures S:MicrobiologyandImmunologyofInfection(2SWS)MandatoryAttendance
3 Lecturers Prof.Dr.D.Vöhringer,Prof.Dr.S.Krappmann,PDDr.A.Lührmannandothers
4 Modulecoordinator Prof.Dr.med.C.Bogdan
5 Contents
MolecularMicrobiologyandImmunologyofInfectionThestudentspresentanddiscussbasicprinciplesofhost-pathogeninteractions,cellularandmolecularregulationofimmuneresponses,defensemechanismsagainstpathogensandmolecularescapestrategiesusingselectedkeypublica-tionsfromscientificjournals.Theseminarcoversthefollowingaspects:
• Adhesionandinvasionofpathogens• Bacterialsecretionsystems• Modulationofintracellulartransportofproteinsandvesicles• Bacterialtoxins• Pathogenrecognitionandinnateimmunity• Diversity,plasticityandfunctionofThelpercells• AntiviralfunctionsofCD8Tcells• Innatelymphoidcells• Fungalpathogens• Secondarymetabolitesoffungi• Immuneresponsetofungi• Protozoaninfectionsandimmuneresponse• Pathogenicityofhelminths• Immuneresponsetohelminths• Immuneevasionofinfectiouspathogens,pathogenpersistence
6 Learningobjectives
andskills
Thestudents
• obtainprofoundsubject-specificknowledgeinmolecularmicrobiologyandimmunologyofinfection.
• obtainskillsforacriticalanalysisandinterpretationofscientificdata.• read,presentandanalyzecurrentprimaryscientificliterature• independentlysolveproblemsinthefieldofmicrobiologyandimmunol-
ogyofinfectionandpresenttheirsolutionsinoralandwrittenform• traintheirabilityfordiscussionandteamworkbyworkinginsmall
groups• giveandreceivecriticalfeedbacktoandfromfellowstudents
7 Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine
8 Integrationincurricu- Electivecompulsorymodule,1stsemester
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea2–ElectiveCompulsoryModules
24
lum
9
Modulecompatibility M.Sc.MolecularMedicine
10 Methodofexamina-tion
Presentation30min(24651)andtermpaper15-20pages(24652)
11 Gradingprocedure Gradeofthetermpaper
12 Modulefrequency Annuallyinthewinterterm
13 WResitexamination Twice
14 Workload Classtime30h
Studytime120h
15 Moduleduration 1term
16 Teachingandexami-nationlanguage
English
17 Recommendedrea-
ding
1. General
• Schaibleetal.IntracellularNichesofMicrobes:aPathogensGuideThroughtheHostCell(1sted.2009);
• Salyers and Witt: Bacterial Pathogenesis (3rd ed. January 2011)• Kaufmann,Rouse,Sacks:TheImmuneResponsetoInfection(1sted.
2011);• Abbas,Lichtman,PillaiCellularandMolecularImmunology,8thed.2015
2. Specificprimaryliterature(originalarticles,reviewarticles)willbehandedouttothestudents
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea2–ElectiveCompulsoryModules
25
1810-SeminarModuleA1.3:MolecularImaging1 Modulename A1.3–MolecularImaging(2470) 5ECTS
2 Courses/lectures S:MolecularImaging(2SWS)MandatoryAttendance
3 Lecturers Prof.Dr.D.C.Lie,Prof.Dr.T.Bäuerleandothers
4 Modulecoordinator Prof.Dr.D.C.Lie
5 Contents
Thestudentspresentanddiscussbasicprinciplesofkeymethodsinmolecularimagingusingselectedkeypublicationsfromscientificjournals.Thestudentsareintroducedtotheoreticalandpracticalaspectsof
• opticalimagingmethods• smallanimalimaging• transgenicreporterdesign
6 Learningobjectivesandskills
Thestudents
• obtainprofoundsubject-specificknowledgeinmolecularimaging.• obtainskillsforacriticalanalysisandinterpretationofscientificdata.• read,presentandanalyzecurrentprimaryscientificliterature.• transfertheoreticalknowledgeinimagingtechnologiestoresearchpro-
jects.• judgethetechnologicalrequirementsofbiomedicalimagingmethods
andpresenttheirsolutionsinoralandwrittenform.• getexperienceinpreparingprobesforbiomedicalimaging.• traintheirabilityfordiscussionandteamworkbyworkinginsmall
groups.• giveandreceivecriticalfeedbacktoandfromfellowstudents
7 Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine
8 Integrationincurricu-lum
Electivecompulsorymodule,1stsemester
9
Modulecompatibility M.Sc.MolecularMedicine
10 Methodofexamina-tion
Presentation30min(24701)andtermpaper15-20pages(24702)
11 Gradingprocedure Gradeofthetermpaper
12 Modulefrequency Annuallyinthewinterterm
13 WResitexamination Twice
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea2–ElectiveCompulsoryModules
26
14 Workload Classtime:30h
Studytime:120h
15 Moduleduration 1term
16 Teachingandexami-nationlanguage
English
17 Recommendedrea-
ding
Weisslederetal.,MolecularImaging,People’sMedicalPublishingHouse,newest
edition
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea2–ElectiveCompulsoryModules
27
1820-SeminarModuleA2.1:MolecularNeuroscience1 Modulename A2.1–MolecularNeuroscience(2475) 5ECTS
2 Courses/lectures Seminar(2SWS),MandatoryAttendance
3 Lecturers Prof.Dr.C.Alzheimer,Prof.Dr.R.Enz,Prof.Dr.J.Kornhuber,Prof.Dr.J.Winkler,Prof.Dr.M.Wegnerandothers
4 Modulecoordinator Prof.Dr.R.Enz
5 Contents
Thestudentspresentanddiscussbasicprinciplesofneuroscienceusingselectedkeypublicationsfromscientificjournals.Theseminarcoversthefollowingaspects:
• Molecularprinciplesofsynapticneurotransmission• Higherbrainfunctions(e.g.learningandmemory,dementia,sleep)• Sensorysystems• Plasticityinthecentralnervoussystem• Molecularcausesofdisordersinthenervoussystem(e.g.blindness,
neurodegenerativediseases,depression,addiction,stroke)• Glialbiologyanddisease• Musclebiologyanddisease• Presentationofpatientsintheneurologydepartment
6 Learningobjectivesandskills
Thestudents
• obtainprofoundsubject-specificknowledgeinmolecularandclinicalneuroscience.
• obtainskillsforacriticalanalysisandinterpretationofscientificdata.• read,presentandanalyzecurrentprimaryscientificliteratureembed-
dedwithintheup-to-datescientificandtherapeuticbackground.• learnthedesignofexperimentalstrategiesandtechniquessuitedtoan-
swerscientificquestionsandpresenttheirsolutionsinoralandwrittenform.
• traintheirabilityfordiscussionandteamworkbyworkinginsmallgroups.
• giveandreceivecriticalfeedbacktoandfromfellowstudent.
7 Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine
8 Integrationincurricu-lum
Electivecompulsorymodule,2ndsemester
9
Modulecompatibility M.Sc.MolecularMedicine
10 Methodofexamina-
tion
Presentation30min(24751)andtermpaper15-20pages(24752)
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea2–ElectiveCompulsoryModules
28
11 Gradingprocedure Gradeofthetermpaper
12 Modulefrequency Anuallyinthesummerterm
13 WResitexamination Twice
14 Workload Classtime30h,Studytime:120h
15 Moduleduration 1term
16 Teachingandexami-
nationlanguage
English
17 Recommendedrea-ding
PrinciplesinNeuralScience,Ed.Kandel,Schwartz,Jessel,McGrawHillBasicNeurochemistry7.Auflage,Ed.Siegel,Albers,Brady,Price,AcademicPress
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea2–ElectiveCompulsoryModules
29
1820-SeminarModuleA2.2:EssentialConceptsinModernVirology1 Modulename A2.2–EssentialConceptsinModernVirology(2480) 5ECTS
2 Courses/lectures S:EssentialConceptsinModernVirology(2SWS)MandatoryAttendance
3 Lecturers Prof.Dr.K.Überla,Prof.Dr.M.Marschall,Prof.Dr.T.Stammingerandothers
4 Modulecoordinator Prof.Dr.ManfredMarschall
5 Contents
Lectureserieswithexercisesinmodernvirology.Thestudentspresentanddis-cussbasicprinciplesofmolecularandmedicalvirologyusingselectedcurrentand/orclassicalpublicationsfromscientificjournals.Theseminarcoversthefollowingaspects:
• antiviraltherapyandprophylaxis• vaccinationstrategies• tumorigenictransformationmediatedbyviruses• epigeneticsofviralgenomes• viralregulatoryproteins• virus-basedvectors• immunecontrolofviralinfections
6 Learningobjectivesandskills
Thestudents
• obtainprofoundsubject-specificknowledgeinmolecularandmedicalvi-
rology.• obtainskillsforacriticalanalysisandinterpretationofscientificdata.• read,present,analyzeandevaluatecurrent/classicalprimaryscientific
literature.• learnthedesignofexperimentalstrategiesandtechniquessuitedtoan-
swerscientificquestionsandpresenttheirsolutionsinoralandwrittenform.
• traintheirabilityfordiscussionandteamworkbyworkinginsmallgroups.
• giveandreceivecriticalfeedbacktoandfromfellowstudent.
7 Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine
8 Integrationincurricu-lum
Electivecompulsorymodule,2ndsemester
9 Modulecompatibility M.Sc.MolecularMedicine
10 Methodofexamina-tion
Presentation30min(24801)andtermpaper15-20pages(24802)
11 Gradingprocedure Gradeofthetermpaper
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea2–ElectiveCompulsoryModules
30
12 Modulefrequency Annuallyinthesummerterm
13 WResitexamination Twice
14 Workload Classtime:30hStudytime:120h
15 Moduleduration 1term
16 Teachingandexami-nationlanguage
English
17 Recommendedrea-
ding
Willbedeterminedindividuallybypreparingdiscussionswiththespecifictutors.
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea2–ElectiveCompulsoryModules
31
1820-SeminarModuleA2.3:Molecularandtranslationalconceptsofcardiacandrenaldisease
1 Modulename A2.3–Molecularandtranslationalconceptsofcar-diacandrenaldisease(2485)
5ECTS
2 Courses/lectures S:Seminar(2SWS)MandatoryAttendance
3 Lecturers Prof.Dr.K.-U.Eckardt,Prof.Dr.F.Engel,Prof.Dr.C.Korbmacher,Prof.Dr.A.Ludwig,Prof.Dr.T.Volk
4 Modulecoordinator Prof.Dr.T.Volk
5 Contents
Thestudentspresentanddiscussbasicprinciplesofheartandremaldiseasesusingselectedkeypublicationsfromscientificjournals.Theseminarcoversthefollowingaspects:
• Molecular,pathophysiologicalandpathologicalcauses,signalingcas-cadesandmechanismsofhumancardiac,renalandcirculatorydiseasesincludingheartfailure,cardiacarrhythmia,tubularandglomerulardis-ease,renalfailureandhypertension.
• up-to-dateexperimentalapproaches,techniquesandtranslationalcon-ceptsinphysiology,pharmacology,pathologyandexperimentalmedi-cine.
6 Learningobjectivesandskills
Thestudents• obtainprofoundsubject-specificknowledgeandsubstantialexpertisein
understandingmolecularmechanismsofdiseasedevelopmentandpro-
gression.• obtainskillsforacriticalanalysisandinterpretationofscientificdata.• read,present,analyzeandevaluatecurrentprimaryandreviewlitera-
ture.• learnthedesignofexperimentalstrategiesandtechniquessuitedtoan-
swerscientificquestionsandpresenttheirsolutionsinoralandwrittenform.
• traintheirabilityfordiscussionandteamworkbyworkinginsmallgroups.
• giveandreceivecriticalfeedbacktoandfromfellowstudent.
7 Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine
8 Integrationincurricu-lum
Electivecompulsorymodule,2ndsemester
9 Modulecompatibility M.Sc.MolecularMedicine
10 Methodofexamina-
tion
Presentation30min(24851)andtermpaper15-20pages(24852)
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea2–ElectiveCompulsoryModules
32
11 Gradingprocedure Gradeofthetermpaper
12 Modulefrequency Annuallyinthesummerterm
13 WResitexamination Twice
14 Workload Classtime:30hStudytime:120h
15 Moduleduration 1term
16 Teachingandexami-
nationlanguage
English
17 Recommendedrea-ding
Thenecessaryliterature,consistingoforiginalandreviewarticleswillbesuppliedbythelecturers.
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea2–ElectiveCompulsoryModules
33
1830-SeminarModuleA3.1:MolecularOncology1 Modulename A3.1–MolecularOncology(2490) 5ECTS
2 Courses/lectures S:(2SWS)MandatoryAttendance
3 Lecturers Prof.Dr.J.Behrens,Prof.Dr.T.Brabletz,Prof.Dr.M.Stürzl,Prof.Dr.A.Boßerhoff
4 Modulecoordinator Prof.Dr.J.Behrens
5 Contents
Thestudentspresentanddiscussbasicprinciplesofmolecularoncologyandtranslationalaspectsusingselectedkeypublicationsfromscientificjournals.Theseminarcoversthefollowingaspects:
• oncogenesandtumorsuppressorgenes• oncogenicsignalingpathways• moleculartherapies• animalmodels• molecularclassificationanddiagnosis• tumormicroenvironment• angiogenesis• tumorimmunology
6 Learningobjectivesandskills
Thestudents
• obtainprofoundsubject-specificknowledgeandsubstantialexpertiseinunderstandingmolecularmechanismsoftumordevelopmentandpro-
gression.• obtainskillsforacriticalanalysisandinterpretationofscientificdata.• read,present,analyzeandevaluatecurrentprimaryliterature.• learnthedesignofexperimentalstrategiesandtechniquessuitedtoan-
swerscientificquestionsandpresenttheirsolutionsinoralandwrittenform.
• traintheirabilityfordiscussionandteamworkbyworkinginsmallgroups.
• giveandreceivecriticalfeedbacktoandfromfellowstudent
7 Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine
8 Integrationincurricu-lum
Electivecompulsorymodule,3rdsemester
9
Modulecompatibility M.Sc.MolecularMedicine
10 Methodofexamina-tion
Portfolio:presentation30min(24901)andwrittenexam90min(24902)
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea2–ElectiveCompulsoryModules
34
11 Gradingprocedure Gradeofthewrittenexam
12 Modulefrequency Annuallyinthewinterterm
13 WResitexamination Twice
14 Workload Classtime30hStudytime:120h
15 Moduleduration 1term
16 Teachingandexami-
nationlanguage
English
17 Recommendedrea-ding
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea2–ElectiveCompulsoryModules
35
1830-SeminarModuleA3.2:CurrentConceptsofImmunology1 Modulename A3.2–CurrentConceptsofImmunology(2495) 5ECTS
2 Courses/lectures S:Immunology(2SWS)MandatoryAttendance
3 Lecturers Prof.Dr.H.-M.Jäck,PDDr.D.Mielenz,Dr.W.Schuh,Dr.J.Wittmann
4 Modulecoordinator Prof.Dr.H.-M.Jäck
5 Contents Thestudentspresentanddiscussimportantphysiologicandpathologicprocessesinbasicandclinicalimmunologyusingselectedkeypublicationsfromscientificjournals.Inaninteractiveround-tableformat,eachstudentwilldeveloptogetherwiththeclassthehypothesis,theexperimentalset-up,thekey-experiment(s)andtheoveralltake-homemessageoftherespectivepublication.
6 Learningobjectivesandskills
Thestudents
• obtainprofoundsubject-specificknowledgeinmolecular,cellularand
clinicalimmunology.• obtainskillsforacriticalanalysisandinterpretationofscientificdata.• read,present,analyzeandevaluatecurrentprimaryliterature.• learnthedesignofexperimentalstrategiesandtechniquessuitedtoan-
swerscientificquestionsandpresenttheirsolutionsinoralandwrittenform.
• traintheirabilityfordiscussionandteamworkbyworkinginsmallgroups.
• giveandreceivecriticalfeedbacktoandfromfellowstudents.
7 Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine
8 Integrationincurricu-
lum
Electivecompulsorymodule,3rdsemester
9
Modulecompatibility MScMolecularMedicineMScCell-undMolecularBiology(DepartmentBiology)MScLifeScienceEngineering(SchoolofEngineering)
10 Methodofexamina-tion
Presentation(24951)andmoderationoftheround-tablediscussion(24952)
11 Gradingprocedure Gradeofthemoderation
12 Modulefrequency Annuallyinthewintersemester
13 WResitexamination Twice
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea2–ElectiveCompulsoryModules
36
14 Workload Classtime:30h
Studytime:120h
15 Moduleduration 1term
16 Teachingandexami-nationlanguage
English
17 Recommendedrea-
ding
Janeway'sImmunobiology,GarlandScience,newestedition
Immunology,Kuby,W.H.Freeman,newesteditionRoitt'sEssentialImmunology,Wiley-Blackwell,newestedition
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea2–ElectiveCompulsoryModules
37
1830-SeminarModuleA3.3:AnimalModelsinBiomedicalResearch1 Modulename A3.3–AnimalModelsinBiomedicalResearch(2499) 5ECTS
2 Courses/lectures S:(2SWS)MandatoryAttendance
3 Lecturers Prof.Dr.S.v.Hörsten,Prof.Dr.T.Bäuerleandothers
4 Modulecoordinator Prof.Dr.S.v.Hörsten
5 Contents
Thestudentsreviewpresentconceptsinclassification,epidemiology,pathophysiologyandtreatmentofthefollowingmajordiseasesenti-ties:cancer,neurodegenerativedisorders,allergies,autoimmunedis-eases,andmetabolicdisorders.Subsequently,specificdiseasesand/orpathomechanismsarebroughtintofocusandtheirtranslationintoacorrespondinganimalmodelisfurtherelaboratedusingselectedkeypublicationsfromscientificjournals.Theseminarcoverstheapplicationofanimalmodelsincludingzebraf-ish,mice,ratsandlargermammals,fortheinvestigationofdiseasesandtherapeuticapproachesinareassuchas:
• Neoplasiawithfocusonmetastasis• NeurodegenerationincludingAlzheimer´s,Parkinson´s,and
Huntington´sdisease• Allergyincludingasthmaandatopicdermatitis• Autoimmunitywithspecificreferencetomultiplesclerosis• DiabeteswithfocusonTypeIIdiabetes• Specialemphasiswillbegiventosystemsinteractionsaswell
aslimitationsofanimalmodelsincludingbutnotlimitedtotheirstandardization,suitability,andnature-nurturederivedaspectsindiseasesandtheirmodels
6 Learningobjectives
andskills
Thestudents
• obtainprofoundsubject-specificknowledgeinanimaltestingandmodelbasedbiomedicalresearchapproaches.
• obtainskillsforacriticalanalysisandinterpretationofscientificdata.
• read,presentandanalyzecurrentprimaryscientificliterature.• independentlydevelophypothesisandresearchstrategiesand
presenttheirsolutionsinoralandwrittenform.• traintheirabilityfordiscussionandteamworkbyworkingin
smallgroups.• giveandreceivecriticalfeedbacktoandfromfellowstudents.
7 Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine
8 Integrationincurricu-
lum
Electivecompulsorymodule,3rdsemester
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea2–ElectiveCompulsoryModules
38
9
Modulecompatibility M.Sc.MolecularMedicine
10 Methodofexamina-
tion
Presentation30min(24991)andtermpaper15-20pages(24992)
11 Gradingprocedure Gradeofthetermpaper
12 Modulefrequency Annuallyinthewinterterm
13 WResitexamination Twice
14 Workload Classtime:30h
Studytime:120h
15 Moduleduration 1term
16 Teachingandexami-nationlanguage
English
17 Recommendedrea-ding
Willbedeterminedindividuallyeachsemester.
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea2–ElectiveCompulsoryModules
39
1835-ElectiveModule1 Modulename ElectiveModule 5ECTS
2 Courses/lectures Dependsonchosenmodule
3 Lecturers Dependsonchosenmodule
4 Modulecoordinator Dependsonchosenmodule
5 Contents
ThestudentschoosefromthecoursesofferedatFAU• keyqualifications• modulesfromotherbachelor’sandmaster’sprograms,dependingon
availability• seminarsofferedbythemaster’sprogram
Thekeyqualificationsarefaculty-independentcourseoffersthatarenotrelatedtospecificsubjects,e.g.languages,communicationalandpresentationalskills.Modulesfromotherbachelor’sandmaster’sprogramsthatarenotlistedaskeyqualificationscanonlybechosenwithpermissionfromthemodulecoordinator.ElectivemodulesinmolecularmedicineAdditionalseminarsfromtheelectivecompulsorypartofthemaster’sprograminmolecularmedicinedependonavailability.Additionalelectivemodulesof-feredbythemaster’sprogramarelistedinthemodulemanual.Additionalre-searchmodulesorinternshipsneedtheapprovalofthestudyboard.
6 Learningobjectivesandskills
Thestudents
• cangaininsightintodiverseacademictopics• canacquiresoftskillsthatpromotetheiremployability
• canbroadentheirgeneraleducation• cangainexpertiseinspecificsubjects
7 Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine
8 Integrationincurricu-lum
Electivemodule,1stsemester
9
Modulecompatibility M.Sc.MolecularMedicine
10 Methodofexamina-
tion
Dependonchosenmodule
11 Gradingprocedure Pass/fail
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea2–ElectiveCompulsoryModules
40
12 Modulefrequency Everysemester
13 WResitexamination Twice
14 Workload Dependsonchosenmodule
15 Moduleduration 1term
16 Teachingandexami-nationlanguage
Dependsonchosenmodule
17 Recommendedrea-
ding
Dependsonchosenmodule
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea2–ElectiveCompulsoryModules
41
2425-ProjectDevelopment1 Modulename 2425-ProjectDevelopment 10ECTS
2 Courses/lectures
P:laboratorycourse(6SWS)T:JournalClub(1SWS)
3 Lecturers Alllecturersofthemaster’sprogram
4 Modulecoordinator Prof.Dr.A.Boßerhoff
5 Contents
Laboratorytraininganddevelopmentofaresearchprojectinpreparationofthemaster’sthesis.Themodulehasamaximumdurationof6weeksandiscom-posedof:
• atutorial,inwhichthestudentandtheadvisordiscusspossibilitiesofaresearchprojectbasedonthecurrentliterature
• laboratorytrainingforthecollectionofpreliminarydata• writingandpresentationofaresearchproposal
6 Learningtargetsandskills
Thestudents
• gaininsightintoaresearchtopicoftheirchoiceandindependentlystudythecurrentliterature
• workandintegratethemselvesinestablishedresearchgroups• applytherulesofgoodscientificpracticetoexperimentation,documen-
tationanddataanalysis
• utilizemodernexperimentaltechniquestocollectscientificdataandcriticallyinterprettheirresults
• evaluatetheirdata,comparethemtopublishedresultsanddiscusstheir
findingswiththeadvisor(s)andtheresearchgroup• developaresearchplanforasixmonthsmaster’sproject
7 Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine
8 Integrationincurricu-lum
Electivecompulsorymodule,3rdsemester
9
Modulecompatibility M.Sc.MolecularMedicine
10 Methodofexamina-tion
Projectplan5-10pages(24251)
Proposedprojectandhypothesis(10lines)Background(1/2-1page)Preliminarydatafromthelaboratorycourse(2-4pages)
Timetableforthemaster’sproject(1/2page)
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea2–ElectiveCompulsoryModules
42
Costcalculation(1page)
References(max.10)
Font:Arial,size:11pt,spacing:1,5x,legendsbeneathimagesortablesin9pt
11 Gradingprocedure Gradeoftheprojectplan
12 Modulefrequency Eachsemester
13 WResitexamination Twice
14 Workload Classtimeandstudytime:300h
15 Moduleduration 1term
16 Teachingandexami-
nationlanguage
English
17 Recommendedrea-ding
Individuallydefinedbytheadvisor
43
Area3–ElectiveCompulsoryModulesB
CurricularCategoriesandModuleNames ECTS Semester
Area3–ElectiveCompulsoryModulesB 25 Areagrade
ExternalModule 25 2.+3. Graded
Alternativepossibility:choiceofmodulesfor25ECTSfromthefollowing
ExternalModulesfor10,15or20ECTS 10,15
or20
Graded
ResearchModulesatFAUfor10ECTS 10 Graded
ElectiveModule 5 Pass/fail
Theareagradeiscalculatedastheaverageofthemodulesweightedbythemodules’ECTSpoints.Thearea3gradecontributesapprox.21%tothefinalmaster’sgrade(25/120ECTS).
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea3–ElectiveCompulsoryModules
44
1850-B1-ExternalModule1 Modulename B1–ExternalModule(2610) 25ECTS
2 Courses/lectures
P:5monthscoursesorplacementatanexternalresearchinstitutionorcompany
3 Lecturers AdvisorsoftheMolecularMedicineprogram
4 Modulecoordinator Headoftheauditcommittee
5 Contents
Thestudentcan• followacoursecurriculumfromadifferentuniversityor• doalaboratorycourseatanationalorinternationalresearchinstituteor• doacompany/industryplacement
Allcoursesandplacementsmustbeinagreementwiththestudyboardbeforeexecution(learningagreement)
6 Learningobjectives
andskills
Thestudents• cangaininsightintointernationalandindustrialresearchenvironments• canacquirespecializedknowledgeandpracticalskillsinaresearchfield
oftheirchoice• independentlyorganizethecurriculum• copewithunfamiliarsituations• canimprovetheirlanguageskills• presenttheirworkinwrittenform
7 Prerequisite EnrollmentintheM.Sc.programofMolecularMedicine
8 Integrationincurricu-lum
Electivecompulsorymodule,2ndand3rdsemester
9 Modulecompatibility M.Sc.MolecularMedicine
10 Methodofexamina-
tion
Dependsonchosencontent
Placement/laboratorycourse:presentation30minpass/fail(26101)andproto-col,usually20-30pages(graded)(26102)
Ifthestudentfollowsacoursecurriculumatadifferentuniversitythemodules,ECTSandgradeswillbetransferred.
11 Gradingprocedure Gradeoftheexamination(s)
12 Modulefrequency Annually
13 WResitexamination Twice
14 Workload 750h
15 Moduleduration 2terms
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea3–ElectiveCompulsoryModules
45
16 Teachingandexami-
nationlanguage
Dependsonchoice
17 Recommendedrea-ding
Dependsonchoice
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea3–ElectiveCompulsoryModules
46
B2-ExternalModule1860/1870/18801 Modulename B2.1–ExternalModule(2615)
B2.2–ExternalModule(2620)B2.3–ExternalModule(2625)
20ECTS15ECTS10ECTS
2 Courses/lectures
B2.14monthscoursesorplacementB2.23monthscoursesorplacementB2.32monthscoursesorplacementatanexternalresearchinstitutionorcompany
3 Lecturers AdvisorsoftheMolecularMedicineprogram
4 Modulecoordinator Headoftheauditcommittee
5 Contents
Thestudentcan• followacoursecurriculumfromadifferentuniversityor• doalaboratorycourseatanationalorinternationalresearchinstituteor• doacompanyplacement
Allcoursesandplacementsmustbeinagreementwiththestudyboardbeforeexecution(learningagreement).
6 Learningtargetsandskills
Thestudents• cangaininsightintointernationalandindustrialresearchenvironments• canacquirespecializedknowledgeandpracticalskillsinaresearchfield
oftheirchoice• independentlyorganizethecurriculum• copewithunfamiliarsituations• canimprovetheirlanguageskills• presenttheirworkinwrittenform
7 u
ire
Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine
8 Integrationincurricu-lum
Electivecompulsorymodule,2ndand3rdsemester
9
Modulecompatibility M.Sc.MolecularMedicine
10 Methodofexamina-tion
DependsonchosencontentInternship/laboratorycourse:presentation30min(pass/fail)andprotocol,usu-
ally20-30pages(graded)Ifthestudentfollowsacoursecurriculumatadifferentuniversity,themodules,
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea3–ElectiveCompulsoryModules
47
ECTSandgradeswillbetransferred.
11 Gradingprocedure Gradeoftheexamination(s)
12 Modulefrequency
13 WResitexamination Twice
14 Workload B2.1:600hB2.2:450h
B2.3:300h
15 Moduleduration 1-2terms
16 Teachingandexami-nationlanguage
Dependsonchoice
17 Recommendedrea-ding
Dependsonchoice
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea3–ElectiveCompulsoryModules
48
B3-LaboratoryResearchModule1 Modulename B3–LaboratoryResearchModule(2630,2635) 10ECTS
2 Courses/lectures
P:2monthslaboratorycourseatFAU
3 Lecturers AdvisorsoftheMolecularMedicineprogram
4 Modulecoordinator Headoftheauditcommittee
5 Contents
ThestudentsworkonabiomedicalresearchprojectinaFAUlaboratoryoftheirchoice.Theyindependentlystudytherelatedliterature,plan,executeanddocumentexperimentsandwritearesearchprotocol.Thelaboratorytimecanalsobesplitbetweentworesearchgroups(collaborativesupervision;oneprotocol).
6 Learningtargetsand
skills
Thestudents• acquirespecializedknowledgeinaresearchfieldoftheirchoice• integrateintoexistingresearchgroups• followtherulesofgoodscientificpractice• plan,performanddocumentresearchexperiments• utilizemodernexperimentaltechniques• presenttheirworkinwrittenform
7 uire
Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine
8 Integrationincurricu-lum
Electivecompulsorymodule,2ndand3rdsemester
9
Modulecompatibility M.Sc.MolecularMedicine
10 Methodofexamina-
tion
Presentation30minandprotocolofusually20-30pages
11 Gradingprocedure Gradeoftheprotocol
12 Modulefrequency Eachsemester
13 WResitexamination Twice
14 Workload 300h
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea3–ElectiveCompulsoryModules
49
15 Moduleduration 1term
16 Teachingandexami-
nationlanguage
Dependsonchoice
17 Recommendedrea-ding
Dependsonchoice
50
Area4–Master’sThesis
CurricularCategoriesandModuleNames ECTS Semester
Area4–Master‘sThesis 30 Areagrade
Master’sThesis 25 4. Graded
Master’sColloquium 5 4. Graded
Theareagradeiscalculatedastheaverageofthemodulesweightedbythemodules’ECTSpoints.Thearea4gradecontributes25%tothefinalmaster’sgrade(30/120ECTS).
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea4–MasterThesis
51
Master’sThesis1 Modulename Master‘sThesis 25ECTS
2 Courses/lectures
Researchproject
3 Lecturers Thesisadvisorsoftheprogram
4 Modulecoordinator Headoftheauditcommittee
5 Contents Independentinvestigationofanup-to-dateresearchquestionfromthefieldofmolecularmedicine:laboratorywork,dataanalysisandwrittenpresentation.Generally,thestudentsworkontheresearchplansthattheydevisedinthemodule“ProjectDevelopment”.Achangeoftopicorlaboratorymustbeap-provedbythestudyboard.
6 Learningtargetsand
skills
Thestudents
• gaintheabilitytoworkonacurrentscientificproblemoveraperiodof
5-6months• applytherulesofgoodscientificpracticetoexperimentation,documen-
tationanddataanalysis
• broadentheirskillstoplan,structureandworkoncomplexproblems• acquiresubjectspecificknowledgeinthechosenresearchfield• planandmanagetheirprojectwithinthegiventimeframe
• developconceptsandapproachestosolveascientificproblem• criticallyanalyzeandreflectontheories,concepts,terminology,limits
andspecificfeaturesoftheirchosentopic
• chooseappropriatescientificmethodsandapplythemtonewandinter-disciplinarycontents
• presentthedatainascientificallycorrectform
• present,interpretanddefendsubjectspecificcontentsinaclear,audi-ence-orientedform
7 Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine
Thestudentmusthaveacquired80ECTScreditpointsfromthecurriculumprior
tostartingthemaster’sproject
8 Integrationincurricu-lum
4thsemester
Attention:closetimingwiththemodule“Master’scolloquium”
9
Modulecompatibility M.Sc.MolekulareMedizin
10 Methodofexamina- WrittenThesis
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea4–MasterThesis
52
tion Writtenelaborationinformofascientificmanuscript.Itdescribesthescientific
findingsaswellasthewayleadingtothesefindings.Itcontainsjustificationsfordecisionsregardingchosenmethodsforthethesisanddiscardedalternatives.Thestudent’sownsubstantialcontributiontotheachievedresultshastobeevi-
dent.Formoreinformation,refertoNo.18.
11 Gradingprocedure Gradeofthewrittenthesis(arithmeticmeansofthetwoexpertreports)
12 Modulefrequency Eachsemester
13 WResitexamination once
14 Workload Thethesishastobepreparedwithin6months
15 Moduleduration 1Semester
16 Teachingandexami-
nationlanguage
English
17 Recommendedrea-ding
Dependsonthesissubject
18 Additionalinformati-
on
-Themaster’sthesishastoberegisteredinAprilforthesummertermandin
Octoberforthewintertermusingtheofficialformissuedbythestudyboard.
-Thetimelimitforthepreparationofthemaster’sthesisis6months.Thethe-sisadvisorsareaskedtopayattentiontoensureanadequateextentofthetreatedsubject.
-Anextensionuptoonemonthispossibleunderwellfoundedcircumstances.-Normally,thethesiswillbeperformedinthesamelabasthemodule“ProjectDevelopment”onthesubjectofthestudent’sprojectproposal.Achangeof
laboratoryorsubjectmustbeapprovedbythestudyboard.-Itisrecommendedtoinvestfivemonthsintotheexperimentalworkandonemonthintowritingthethesis.
ThethesismustbewritteninEnglish.ItcanonlybewritteninGermanuponapprovalofthestudyboard.Itmustadheretothefollowingformalrequire-ments:
-Font:Arial,size:11pt,spacing:1,5x,legendsbeneathimagesortablesin9pt.-Thethesishastheformofascientificpublication,includinganindex,alistofabbreviations,andthechapters1.AbstractsinEnglishandGerman,2.Introduc-
tion,3.MaterialandMethods,4.Results,5.Discussion,6.FuturePerspectivesand7.References.
-TheAbstractshouldnotexceed400words(1page).Thewholethesismaynotexceed40.000wordsandshouldgenerallybeshorterthan100pages.Thethesismustincludeastatement,thatnootherthanthestatedsourcesand
aidswereused.-Thethesismustbesubmittedontimetotheadvisor(s)intwoprintedversionsandanelectronicversion(PDF).Thesubmissionhastobedocumentedonthe
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea4–MasterThesis
53
officialformissuedbythestudyboard.
-Bothadvisorsprovideindependentreports(1-2pages)withinonemonthaftersubmission.Thegradingadheresto§18Prüfungsordnung.
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea4–MasterThesis
54
Master‘sColloquium1 Modulename Master‘sColloquium 5ECTS
2 Courses/lectures Colloquium
3 Lecturers Thesisadvisorsoftheprogram
4 Modulecoordinator Headoftheauditcommittee
5 Contents Presentationofthemaster’sthesisintheframeworkofanall-daycolloquium.Thestudentspresenttheirworkinaseminar,inwhichthescientificqualityandthescientificindependenceofhis/herachievementsareevaluated.Thethesisadvisorsevaluatethestudents’knowledgeintheresearchsubjectandrelatedsubjects.
6 Learningtargetsandskills
Thestudents
• presenttheirdatainascientificallycorrectform• present,interpretanddefendtheirresearchresultsinaclear,audience-
orientedform
• comparetheirresultstopublisheddata• transfersubject-specificknowledgetootherareasofbiomedicine
7 Prerequisites EnrollmentintheM.Sc.programofMolecularMedicine
8 Integrationincurricu-lum
4thsemester
9 Modulecompatibility M.Sc.MolekulareMedizin
10 Methodofexamina-tion
Oralexam:presentation,discussionandopenquestions,approx.15min
11 Gradingprocedure Gradeoftheoralexam
12 Modulefrequency Eachsemester;
summerterm:ColloquiuminSeptemberorOctober
winterterm:Presentationinpresenceoftheexaminersboard
13 WResitexamination once
14 Workload 1-2dayscolloquiumandpreparation
15 Moduleduration 1Semester
ModuleManual:MolecularMedicine,MasterofScience–FAUErlangen-NürnbergArea4–MasterThesis
55
16 Teachingandexami-
nationlanguage
English
17 Recommendedrea-ding