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Monday, March 19,2012
OBJECTIVES:
1.What is Meiosis?2.Why is it needed?3.Outline and order the steps.4.Explain the events of each step.5.Identify the exclusive events and explain their
importance.6.Explain the outcome of meiosis.7.Distinguish between spermatogenesis and oogenesis.
Brainteaser
What needs an answer, but doesn't ask a question?
Lets Review!
Cell Cycle (IPMATC)Mitosis
Prophase? Metaphase? Anaphase? Telophase?
1 2 3 4
5 6 7
MEIOSIS
What is it? Making sex cells or gametes (sperm & eggs).
Who does it? All sexually reproducing organisms.
Where does it happen? In males- in the testes. In females- in the ovaries.
Why does it happen? So when organisms reproduce they
retain their species’ chromosome number.
Why is a different process needed? 1) Chromosome # needs to be cut in half 2) Creates genetic diversity (helps evolution of species)
MEIOSIS
The process by which one diploid cell creates four haploid cells
Diploid Cell (2n) – a cell that contains both sets of homologous chromosomes
Haploid Cell (n) – a cell that contains one set of homologous chromosomes
Homologous Chromosome – corresponding (matching) chromosomes from a female and male parent.
Remember, humans have 23 pairs of chromosomes - 46 total.
Pairs 1-22 are said to beHomologous chromosomes
(they go together because they have same traits but they are not identical.)
Gene for eye color
Gene for hair color
The goal is to make….haploid sex cells
Father Mother
Spermatogenesis
Oogenesis
3 polar bodies
1 viable egg 4 viable sperm
MEIOSIS HAS TWO STAGES:
Meiosis 1 and Meiosis 2
Meiosis 1
This is the stage where the chromosome number is halved
Includes 4 stages:•Prophase 1•Metaphase 1•Anaphase 1•Telophase 1
Prophase 1 is similar in some ways toprophase in mitosis.
Chromosomes condense.Spindle fibers appear.Nucleus and nucleolus disappear.
THIS PROCESS ISCALLED SYNAPSING
•LINED UPHOMOLOGUES ARECALLED TETRADS
UNLIKE in mitosis, homologouschromosomes line up next to each
otherduring prophase
THIS IS CALLED “CROSSING OVER”
When homologous chromosomes
hang out so close to each other,
they sometimes swap parts!
WHY IS THIS IMPORTANTFOR A SPECIES’
LONG-TERM SURVIVAL?
Crossing over increasesgenetic diversity
Independent Assortment•Independent assortment produces 2n distinct gametes, where n = the number of unique chromosomes.
•That’s a lot of diversity simply by this mechanism alone.
•In humans, n = 23 and 223 ≈ 8,000,0000.
During metaphase 1, tetrads
line up on a metaphase plate.
The Key Difference Between Mitosis and Meiosis is the Way Chromosomes Uniquely
Pair and Align in Meiosis
Mitosis The first (and distinguishing)
division of meiosis.
MEIOSIS
MEIOSIS I Anaphase I – Spindle fibers pull the homologous
chromosomes toward opposite ends of the cell.
MEIOSIS
MEIOSIS I Telophase I - Meiosis I results in 2 haploid (n)
daughter cells. Each with half the number of chromosomes as the original cell.
In telophase 1, two daughter cells areformed. They are NOT identical! (Why?)
After Meiosis 1…
Homologous chromosomes have been separated.
Two non-identical daughter cells have been formed.
The chromosome number has been cut in half.
WHY NOT?
Chromosomes are NOTduplicated again betweenMeiosis 1 and Meiosis 2.
Meiosis 2 is similar to mitosis
Two identical daughter cells are formed from each of the cells created in Meiosis 1
• Includes 4 Stages:
•– Prophase 2•– Metaphase 2•– Anaphase 2•– Telophase 2
Meiosis II
Meiosis II
Prophase 2: centrioles replicate, spindle reforms and chromosomes move toward the metaphase plate.
Metaphase 2: sister chromatids lined up on the metaphase plate.
Anaphase 2: sister chromatids are separated and pulled toward opposite poles of the cell.
Telophase 2 and Cytokinesis: nuclei form at either pole and both cells each are divided into two very different daughter cells – giving rise to 4 genetically
different haploid cells - 4 gametes.
All together now…
Meiosis and mitosis are two different reproductive processes. What happens ONLY
during meiosis?
A. replication of organelles.B. disappearance of the nucleolus.C. crossing over occurs.D. complete breakdown of the nuclear
membrane.
Which statement is correct?
A. Meiosis is a way to reproduce, but mitosis is not.
B. Meiosis is a way to create diversity, but mitosis is not.
C. During mitosis, chromosomes are copied, but during meiosis chromosomes double.
D. During mitosis, chromosome numbers double, but during meiosis chromosome numbers remain constant.