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Ultrasound Lumify Monitoring of dengue complications using Lumify A case study by Dr Rahajeng Tunjungputri Dr Rahajeng Tunjungputri, who is working as a doctor in Semarang, Indonesia, currently uses the Philips Lumify for detecting severe dengue in Indonesia. “Dengue is worldwide the most common arboviral infection with an estimated number of nearly 400 million cases yearly. It is also an important public health problem in Indonesia. During the rainy season, health facilities treat many people with suspected dengue.” Dengue is mostly a mild disease, but sometimes severe complications occur. The most important complication is a transient vascular leakage syndrome. Hereby, plasma leaks out from blood vessels to the surrounding tissue. Patients can develop pleural fluid or ascites, but if the plasma leakage is severe, hypovolemic shock can occur. This has a high mortality when not treated properly. Severe plasma leakage usually occurs when patients are several days ill. A major challenge for clinicians is the fact that occurrence of severe plasma leakage cannot be reliably predicted.
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Page 1: Monitoring of dengue complications using Lumify › c-dam › b2bhc › de › resource...the availability of portable, bedside ultrasound device can assist greatly in clinical decision

Dr Tunjungputri is currently performing a clinical trial in

dengue patients in Semarang and Jepara, Central Java,

Indonesia, together with researchers from the Radboud

university medical center in Nijmegen, the Netherlands.

The Dutch researchers have previously shown that serial

bedside ultrasonography is helpful in identifying patients

at risk for development of severe dengue. “We use the

Philips Lumify to check all patients daily for early signs

of plasma leakage,” says Dr Tunjungputri. The study team

received a short training from a certified radiologist.

“Our first experiences with the Lumify are positive. The

ultrasound is easy to use and images are of high quality.

But even beyond using it for research purposes, we are

excited to introduce this technique for routine use in

clinical environments.”

“In a country like Indonesia, where clinicians are often overwhelmed by the number of patients and where decisions must be made promptly, the availability of portable, bedside ultrasound device can assist greatly in clinical decision making and patient management.”

Ultrasound

Lumify

Monitoring of dengue complications using LumifyA case study by Dr Rahajeng Tunjungputri

Dr Rahajeng Tunjungputri, who is working as a doctor in Semarang,

Indonesia, currently uses the Philips Lumify for detecting severe dengue

in Indonesia.

“Dengue is worldwide the most common arboviral

infection with an estimated number of nearly 400 million

cases yearly. It is also an important public health problem

in Indonesia. During the rainy season, health facilities

treat many people with suspected dengue.”

Dengue is mostly a mild disease, but sometimes severe

complications occur. The most important complication is

a transient vascular leakage syndrome. Hereby, plasma

leaks out from blood vessels to the surrounding tissue.

Patients can develop pleural fluid or ascites, but if the

plasma leakage is severe, hypovolemic shock can occur.

This has a high mortality when not treated properly.

Severe plasma leakage usually occurs when patients

are several days ill. A major challenge for clinicians is

the fact that occurrence of severe plasma leakage

cannot be reliably predicted.

Dr Tunjungputri says, “In clinical practice, we rely on

clinical features and monitoring of the platelet count

and hematocrit value. The hematocrit is the percentage

volume of red blood cells and this increases during

plasma leakage. However, the hematocrit is often not

sensitive enough.”

An alternative method to monitor plasma leakage is

ultrasonography. Hereby you look for thickening of the

gall bladder wall, pleural fluid and ascites. Scientific

studies have shown that daily ultrasonography better

predicts the development of severe dengue than

hematocrit. Dr Tunjungputri shares, “Unfortunately,

ultrasonography is not routinely performed nowadays

in dengue patients in Indonesia due to financial and

logistical limitations.”

452299152931.indd 1 12/11/2019 13:37

This printed copy is not an official Philips hard copy, use for reference only

Page 2: Monitoring of dengue complications using Lumify › c-dam › b2bhc › de › resource...the availability of portable, bedside ultrasound device can assist greatly in clinical decision

Dr Tunjungputri is currently performing a clinical trial in

dengue patients in Semarang and Jepara, Central Java,

Indonesia, together with researchers from the Radboud

university medical center in Nijmegen, the Netherlands.

The Dutch researchers have previously shown that serial

bedside ultrasonography is helpful in identifying patients

at risk for development of severe dengue. “We use the

Philips Lumify to check all patients daily for early signs

of plasma leakage,” says Dr Tunjungputri. The study team

received a short training from a certified radiologist.

“Our first experiences with the Lumify are positive. The

ultrasound is easy to use and images are of high quality.

But even beyond using it for research purposes, we are

excited to introduce this technique for routine use in

clinical environments.”

“In a country like Indonesia, where clinicians are often overwhelmed by the number of patients and where decisions must be made promptly, the availability of portable, bedside ultrasound device can assist greatly in clinical decision making and patient management.”

“Dengue is worldwide the most common arboviral

infection with an estimated number of nearly 400 million

cases yearly. It is also an important public health problem

in Indonesia. During the rainy season, health facilities

treat many people with suspected dengue.”

Dengue is mostly a mild disease, but sometimes severe

complications occur. The most important complication is

a transient vascular leakage syndrome. Hereby, plasma

leaks out from blood vessels to the surrounding tissue.

Patients can develop pleural fluid or ascites, but if the

plasma leakage is severe, hypovolemic shock can occur.

This has a high mortality when not treated properly.

Severe plasma leakage usually occurs when patients

are several days ill. A major challenge for clinicians is

the fact that occurrence of severe plasma leakage

cannot be reliably predicted. © 2019 Koninklijke Philips N.V. All rights are reserved.Philips reserves the right to make changes in specificationsand/or to discontinue any product at any time without noticeor obligation and will not be liable for any consequencesresulting from the use of this publication. Trademarks are theproperty of Koninklijke Philips N.V. or their respective owners.

philips.com/lumify

4522 991 52931 * NOV 2019

Dr Tunjungputri says, “In clinical practice, we rely on

clinical features and monitoring of the platelet count

and hematocrit value. The hematocrit is the percentage

volume of red blood cells and this increases during

plasma leakage. However, the hematocrit is often not

sensitive enough.”

An alternative method to monitor plasma leakage is

ultrasonography. Hereby you look for thickening of the

gall bladder wall, pleural fluid and ascites. Scientific

studies have shown that daily ultrasonography better

predicts the development of severe dengue than

hematocrit. Dr Tunjungputri shares, “Unfortunately,

ultrasonography is not routinely performed nowadays

in dengue patients in Indonesia due to financial and

logistical limitations.”

Lumify C5-2

Abdominal ultrasound scan using Lumify

452299152931.indd 2 12/11/2019 13:37

This printed copy is not an official Philips hard copy, use for reference only


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