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Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor β Signaling...

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Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor β Signaling Susann Weissmueller, Eusebio Manchado, Michael Saborowski, John P. Morris, Elvin Wagenblast, Carrie A. Davis, Sung-Hwan Moon, Neil T. Pfister, Darjus F. Tschaharganeh, Thomas Kitzing, Daniela Aust, Elke K. Markert, Jianmin Wu, Sean M. Grimmond, Christian Pilarsky, Carol Prives, Andrew V. Biankin, Scott W. Lowe Cell Volume 157, Issue 2, Pages 382-394 (April 2014) DOI: 10.1016/j.cell.2014.01.066 Copyright © 2014 Elsevier Inc. Terms and Conditions
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Page 1: Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor β Signaling Susann Weissmueller, Eusebio Manchado, Michael Saborowski,

Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor β Signaling 

Susann Weissmueller, Eusebio Manchado, Michael Saborowski, John P. Morris, Elvin Wagenblast, Carrie A. Davis, Sung-Hwan Moon, Neil T. Pfister, Darjus F. Tschaharganeh, Thomas Kitzing, Daniela Aust, Elke K. Markert, Jianmin Wu, Sean M. Grimmond, Christian

Pilarsky, Carol Prives, Andrew V. Biankin, Scott W. Lowe 

Cell Volume 157, Issue 2, Pages 382-394 (April 2014)

DOI: 10.1016/j.cell.2014.01.066

Copyright © 2014 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 2: Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor β Signaling Susann Weissmueller, Eusebio Manchado, Michael Saborowski,

Figure 1

Cell 2014 157, 382-394DOI: (10.1016/j.cell.2014.01.066) Copyright © 2014 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 3: Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor β Signaling Susann Weissmueller, Eusebio Manchado, Michael Saborowski,

Figure 2

Cell 2014 157, 382-394DOI: (10.1016/j.cell.2014.01.066) Copyright © 2014 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 4: Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor β Signaling Susann Weissmueller, Eusebio Manchado, Michael Saborowski,

Figure 3

Cell 2014 157, 382-394DOI: (10.1016/j.cell.2014.01.066) Copyright © 2014 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 5: Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor β Signaling Susann Weissmueller, Eusebio Manchado, Michael Saborowski,

Figure 4

Cell 2014 157, 382-394DOI: (10.1016/j.cell.2014.01.066) Copyright © 2014 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 6: Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor β Signaling Susann Weissmueller, Eusebio Manchado, Michael Saborowski,

Figure 5

Cell 2014 157, 382-394DOI: (10.1016/j.cell.2014.01.066) Copyright © 2014 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 7: Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor β Signaling Susann Weissmueller, Eusebio Manchado, Michael Saborowski,

Figure 6

Cell 2014 157, 382-394DOI: (10.1016/j.cell.2014.01.066) Copyright © 2014 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 8: Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor β Signaling Susann Weissmueller, Eusebio Manchado, Michael Saborowski,

Figure 7

Cell 2014 157, 382-394DOI: (10.1016/j.cell.2014.01.066) Copyright © 2014 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 9: Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor β Signaling Susann Weissmueller, Eusebio Manchado, Michael Saborowski,

Figure S1

Cell 2014 157, 382-394DOI: (10.1016/j.cell.2014.01.066) Copyright © 2014 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 10: Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor β Signaling Susann Weissmueller, Eusebio Manchado, Michael Saborowski,

Figure S2

Cell 2014 157, 382-394DOI: (10.1016/j.cell.2014.01.066) Copyright © 2014 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 11: Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor β Signaling Susann Weissmueller, Eusebio Manchado, Michael Saborowski,

Figure S3

Cell 2014 157, 382-394DOI: (10.1016/j.cell.2014.01.066) Copyright © 2014 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 12: Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor β Signaling Susann Weissmueller, Eusebio Manchado, Michael Saborowski,

Figure S4

Cell 2014 157, 382-394DOI: (10.1016/j.cell.2014.01.066) Copyright © 2014 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 13: Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor β Signaling Susann Weissmueller, Eusebio Manchado, Michael Saborowski,

Figure S5

Cell 2014 157, 382-394DOI: (10.1016/j.cell.2014.01.066) Copyright © 2014 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 14: Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor β Signaling Susann Weissmueller, Eusebio Manchado, Michael Saborowski,

Figure S6

Cell 2014 157, 382-394DOI: (10.1016/j.cell.2014.01.066) Copyright © 2014 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 15: Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor β Signaling Susann Weissmueller, Eusebio Manchado, Michael Saborowski,

Cell 2014 157, 382-394DOI: (10.1016/j.cell.2014.01.066) Copyright © 2014 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions

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