Outcome-BasedPayment

“We’re paying for the treatment and patients healed, not for the pills”

Dr. Paulo MacedoMinister of Health of Portugal,

talking about the treatment of Hepatitis C

“It is okay to be tested on that in the process of price-setting, that is fine, we should only be paid for the value we bring”

Marijn Dekkers, Bayer’s CEOon Pharma Times

“I really believe that in the future, companies like Novartis are going to be paid on patient outcomes as opposed to selling the pill”

Joseph Jimenez, Novartis’ CEOon Forbes

36%loss in potential salesfor pharma companies*

*Source: “Patient Adherence: The Next Frontier in Patient Care”, CapGemini

Non-Adherence

50%medicines not taken

as prescribed*

*Source: “Reviving the Primary Care Market”, IMS Health

LookBeyond the Pill

State of the Art

- Hard to set-up- Expensive- Designed to control the patient- Centered in the technology or features

(not in the patient)

Good for the Patient

� Compact

� Portable

� Visual and audible alarm

� Versatile Interior

� Treatment-Specific

� Dosage instructions

� Can integrate withmobile app

� Keep track of medication intake

9 Assess medicationadherence

9 Proximity care

9 Detect missed doses

9 Better outcome

9 Compatible with blisters(easier with regulators)

Good for Payers

Alarm fired at 9:00AM. Snoozed 3 times. Medicine taken at 9:55AM.

Alarm fired at 7:00PM. Medicine not taken.

Data-Rich

� Low cost per unit

� Readily available technology

� Energy efficient(battery lasts ~8 months)

Inexpensive

Easy Integration

adherencedata

Patient Support Program anonymizedreport

PharmaCompanies

How did we get here?

Playing with the Big Guys

€50.000

Big vs Small

Big Companies

9 Regulatory Affairs9 Investment Capacity9 Market Access9 Dealing with Payers9 Retain Talent

Startups

9 Innovating9 Ability to Adapt9 Flexibility9 Disruption9 Attract Talent

Internal Innovation

External Innovation

Innovation Ecosystem

Innovation Ecosystem

Internal Innovation

External Innovation

Internal Innovation

External Innovation

Innovation Ecosystem

DiogoCEO

SofiaOperations

LuísSoftware

JoanaDesign

MárioFirmware

FranciscoHardware

Team

Diogo Ortega

diogo@pharmassistant.net+351 918 491 600

Available for Partnerships