Now, Going Downhill Shouldn’t Include His Brain Performance.Enzogenol®, New Zealand Pine Bark Extract, Boosts and Maintains Brain Performance

The latest clinical research shows significant improvements in brain performance after only

five weeks on Enzogenol®. In this randomized, controlled trial in men ages

50-65, parameters of working memory performance improved to the level

common for men 7–12 years younger.† Enzogenol® – think fast.

Product of New Zealand•

Patented Water-Only Extraction (US5968517)•

OPC Content > 80%•

For sales, samples and information, contact B&D Nutritional Ingredients at 800.546.6113.www.bdnutritional.com

©2008 B&D Nutritional Ingredients. All Rights Reserved.

†Pipingas A., et al. 2008, Phytotherapy Research 22:9, p1168.

Enzogenol®

New Zealand Pine Bark Extract Boostsand Maintains Brain Performance.www.bdnutritional.com/enzogenol.php

Enzogenol®’s Function

• Enzogenol®isapinebarkextractfromNewZealand-grown Pinus Radiata.

• Extractedusingapatentedwater-onlyextractionmethod(no othersolventsorchemicalsinvolved).

• Polyphenoliccomposition:poly-andoligomeric proanthocyanidins,catechins,otherflavonoids, stilbenes,phenolicacid.

IP Position• Patentapplicationforpinebarkextractandproanthocyanidins asacognitive-abilitiesimprovingagent(NZ539962, WO2006126895,natl.phasesfiled:USA,Japan,Taiwan,Malaysia).

Market Opportunity• CombiningEnzogenol®andcocoaextractintoabroad spectrum,OPC-basedcognitionenhancerand/or preserverwithacuteandlong-termbenefits.

• CombiningIPonproanthocyanidisascognitive enhancerstostrengthenmarketposition.

Enzo Nutraceuticals Ltd is a science-based company involved in the research, development and commercialization of natural plant extracts with evidence-based health benefits. The leading product, Enzogenol® is a broad spectrum of antioxidants purified from fresh New Zealand pine bark. This balanced blend of naturally occurring flavonoids is extracted using patented pure-water technology, which avoids the introduction of detrimental solvent residues.

Enzogenol®PineBarkExtract

Enzogenol® NewZealandPineBarkExtract,highpolyphenols,min.70%OPC,purewaterextracted,clinicaldataavailable,forsoliddosage.

DryForm

www.enzogenol.com

Cognitive Function Research• StudyatBrainScienceInstitute,SwinburneUniversity, Melbourne,Australia:42men,50-65yearsold,BMI>25,no signofcognitivedecline,five-weekintervention(moreinfoat: www.enzogenol.com/brainstudy).

• Enzogenol®improvedcognitiveperformanceonworking memorytasksbyreducingresponsetimesinspecific computer-basedtests(spatialworkingmemory,immediate recognitiontask);Pipingas,A.etal.2008Phytotherapy Research22p1168.

• Enzogenol®changedbrainelectricalactivitypatternsshifting thebalancetowardgreaterdecouplingofbrainregions, whichcorrelateshighlywithaccuratedecisionmaking;Pinpingas, A.etal.publicationinpreparation.

• Clinicalsignificance:Reducedresponsetimesareequivalent to7–12yearsofrecoveredbrainperformance(basedon establisheddeclineinresponsetimeswithageusingthesame workingmemorytests).

Forsales,samplesandinformation,contactB&DNutritionalIngredientsat800.546.6113,oronlineat www.bdnutritional.com