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Nadina B Lincoln Jenny L Taylor Kristina Vella Walter P ... B Lincoln Jenny L Taylor Kristina Vella...

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Nadina B Lincoln Jenny L Taylor Kristina Vella Walter P Bouman Kathryn A Radford
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Page 1: Nadina B Lincoln Jenny L Taylor Kristina Vella Walter P ... B Lincoln Jenny L Taylor Kristina Vella Walter P Bouman Kathryn A Radford. Background ... (Donnelly & Karlinsky 1990; BPS

Nadina B Lincoln Jenny L Taylor

Kristina VellaWalter P Bouman

Kathryn A Radford

Page 2: Nadina B Lincoln Jenny L Taylor Kristina Vella Walter P ... B Lincoln Jenny L Taylor Kristina Vella Walter P Bouman Kathryn A Radford. Background ... (Donnelly & Karlinsky 1990; BPS

BackgroundDriving relies on multiple abilities, (e.g. memory, judgement, psychomotor abilities) which can be affected by dementia. In the UK “If you have had, or currently suffer from a medical condition or disability that may affect your driving you must tell the Driver and Vehicle Licensing Agency (DVLA).” (http://www.dvla.gov.uk)There is currently a lack of consistency in the methods used to determine whether a person with dementia is considered safe or unsafe to drive (Donnelly & Karlinsky 1990; BPS 2001)

N B Lincoln - Spring 2009

Page 3: Nadina B Lincoln Jenny L Taylor Kristina Vella Walter P ... B Lincoln Jenny L Taylor Kristina Vella Walter P Bouman Kathryn A Radford. Background ... (Donnelly & Karlinsky 1990; BPS

Previous workLincoln et al. (2006) developed a cognitive test battery for predicting safety to drive in people with dementia

The predictive equation was 88% accurate

N B Lincoln - Spring 2009

Page 4: Nadina B Lincoln Jenny L Taylor Kristina Vella Walter P ... B Lincoln Jenny L Taylor Kristina Vella Walter P Bouman Kathryn A Radford. Background ... (Donnelly & Karlinsky 1990; BPS

Current Study ‐ AIMS1. To establish whether assessments found to 

be predictive of on‐road performance in previous study are predictive in an independent sample

2. To determine whether the predictive validity can be improved by including other measures

N B Lincoln - Spring 2009

Page 5: Nadina B Lincoln Jenny L Taylor Kristina Vella Walter P ... B Lincoln Jenny L Taylor Kristina Vella Walter P Bouman Kathryn A Radford. Background ... (Donnelly & Karlinsky 1990; BPS

ProcedureReferral: letter or phone call

Invitation letter to participant: including consent form and information sheet

Home Visit: discuss the study and administer cognitive assessments (1 or 2 sessions)

Driving Assessment: with specialised driving instructor

Report: to referrer, GP, and participantN B Lincoln - Spring 2009

Page 6: Nadina B Lincoln Jenny L Taylor Kristina Vella Walter P ... B Lincoln Jenny L Taylor Kristina Vella Walter P Bouman Kathryn A Radford. Background ... (Donnelly & Karlinsky 1990; BPS

AssessmentsGeneral level of function: MMSE 

Attention: SDSA Dot Cancellation; Stroop

Executive abilities: SDSA Square Matrices & Road Sign Recognition; BADS Rule Shift & Key Search; Trail Making

Visuospatial perception: VOSP Incomplete Letters, Position Discrimination & Number Location

Memory: SORT Words Immediate; SORT Words Delayed

Information processing: AMIPB Info Processing A

N B Lincoln - Spring 2009

Page 7: Nadina B Lincoln Jenny L Taylor Kristina Vella Walter P ... B Lincoln Jenny L Taylor Kristina Vella Walter P Bouman Kathryn A Radford. Background ... (Donnelly & Karlinsky 1990; BPS

N B Lincoln - Spring 2009

Page 8: Nadina B Lincoln Jenny L Taylor Kristina Vella Walter P ... B Lincoln Jenny L Taylor Kristina Vella Walter P Bouman Kathryn A Radford. Background ... (Donnelly & Karlinsky 1990; BPS

N B Lincoln - Spring 2009

Page 9: Nadina B Lincoln Jenny L Taylor Kristina Vella Walter P ... B Lincoln Jenny L Taylor Kristina Vella Walter P Bouman Kathryn A Radford. Background ... (Donnelly & Karlinsky 1990; BPS

N B Lincoln - Spring 2009

Page 10: Nadina B Lincoln Jenny L Taylor Kristina Vella Walter P ... B Lincoln Jenny L Taylor Kristina Vella Walter P Bouman Kathryn A Radford. Background ... (Donnelly & Karlinsky 1990; BPS

1. Starting Precautions 13. Passing static vehicles 2. Moving Off 14. Merging with traffic stream3. Observation at Side Junctions 15. Anticipating pedestrians4. Observations to rear 16. Anticipating beh. of others5. Use of Signals 17. Use of speed6. Positioning on Road 18. Obedience of road signs7. Cornering 19. Observing speed limits8. Braking 20. Courtesy 9. Accelerating 21. Emergency stop10. Overtaking 22. Reversing11. Driving on roundabouts 23. Parking vehicle12. Driving in traffic lanes 24. Turning right

25. Following too close

Road Assessment

N B Lincoln - Spring 2009

Page 11: Nadina B Lincoln Jenny L Taylor Kristina Vella Walter P ... B Lincoln Jenny L Taylor Kristina Vella Walter P Bouman Kathryn A Radford. Background ... (Donnelly & Karlinsky 1990; BPS

Road AssessmentClassified:

Definitely Safe Probably Safe Probably UnsafeDefinitely Unsafe 

Inter-rater reliability in small sample (n=6)

100% agreement in classification between our driving

instructor and an independent instructor. N B Lincoln - Spring 2009

Page 12: Nadina B Lincoln Jenny L Taylor Kristina Vella Walter P ... B Lincoln Jenny L Taylor Kristina Vella Walter P Bouman Kathryn A Radford. Background ... (Donnelly & Karlinsky 1990; BPS

Recruitment122 people

referred

75recruited

47 not recruited

stopped driving

n=4

notinterested

n=29

licence at DVLA

n=7

completedfull assessment

n= 65

completedonly cognitiveassessment

n=10

othern=7

N B Lincoln - Spring 2009

Page 13: Nadina B Lincoln Jenny L Taylor Kristina Vella Walter P ... B Lincoln Jenny L Taylor Kristina Vella Walter P Bouman Kathryn A Radford. Background ... (Donnelly & Karlinsky 1990; BPS

ParticipantsAge Mean 75.2, SD 6.7, Range 59‐88

GenderMen 50  (77%)Women 15 (23%)

Type of dementiaAlzheimer’s   51%Vascular  21%Other  27%

N B Lincoln - Spring 2009

Page 14: Nadina B Lincoln Jenny L Taylor Kristina Vella Walter P ... B Lincoln Jenny L Taylor Kristina Vella Walter P Bouman Kathryn A Radford. Background ... (Donnelly & Karlinsky 1990; BPS

Driving Outcome

0

5

10

15

20

25

30

Definitely Safe Probably Safe Probably Unsafe DefinitelyUnsafe

28

24

12

1

Lower proportion of unsafe drivers than in previous studies

N B Lincoln - Spring 2009

Page 15: Nadina B Lincoln Jenny L Taylor Kristina Vella Walter P ... B Lincoln Jenny L Taylor Kristina Vella Walter P Bouman Kathryn A Radford. Background ... (Donnelly & Karlinsky 1990; BPS

The AIMS1. To establish whether assessments found to 

be predictive of on‐road performance in previous study are predictive in an independent sample

N B Lincoln - Spring 2009

Page 16: Nadina B Lincoln Jenny L Taylor Kristina Vella Walter P ... B Lincoln Jenny L Taylor Kristina Vella Walter P Bouman Kathryn A Radford. Background ... (Donnelly & Karlinsky 1990; BPS

Was the old equation predictive?71% correctly classified (n=62)

Predicted group membership (cognitive tests)

Unsafe Safe

Road Pass 8 41

Assessment

Fail 3 10

These individuals are those who are actually unsafe, but would have been missed by the equation

Sensitivity for safe drivers=80.4%; Specificity=25.0%; PPV=83.7%; NPV=23.1% N B Lincoln - Spring 2009

Page 17: Nadina B Lincoln Jenny L Taylor Kristina Vella Walter P ... B Lincoln Jenny L Taylor Kristina Vella Walter P Bouman Kathryn A Radford. Background ... (Donnelly & Karlinsky 1990; BPS

The AIMS1. To establish whether assessments found to 

be predictive of on‐road performance in previous study are predictive in an independent sample

2. To determine whether the predictive validity can be improved by including other measures

N B Lincoln - Spring 2009

Page 18: Nadina B Lincoln Jenny L Taylor Kristina Vella Walter P ... B Lincoln Jenny L Taylor Kristina Vella Walter P Bouman Kathryn A Radford. Background ... (Donnelly & Karlinsky 1990; BPS

Could we produce a better equation?

From a hierarchical DFA using the original tests, plus VOSP Number Location we developed a new predictive equation

N B Lincoln - Spring 2009

Page 19: Nadina B Lincoln Jenny L Taylor Kristina Vella Walter P ... B Lincoln Jenny L Taylor Kristina Vella Walter P Bouman Kathryn A Radford. Background ... (Donnelly & Karlinsky 1990; BPS

Results with new equation?83.9% correctly classified (n=62)

Predicted group membership (cognitive tests)

Unsafe Safe

Road Pass 8 41

Assessment

Fail 11 2

These individuals are those who are actually unsafe, but would have been missed by the equation

Sensitivity for safe drivers=95.3%; Specificity=57.9%; PPV=83.7%; NPV=84.6%

These individuals are less of a concern – we would simply recommend that they are tested on the road

N B Lincoln - Spring 2009

Page 20: Nadina B Lincoln Jenny L Taylor Kristina Vella Walter P ... B Lincoln Jenny L Taylor Kristina Vella Walter P Bouman Kathryn A Radford. Background ... (Donnelly & Karlinsky 1990; BPS

Who did the equation miss?

1. Often drove an automatic car (whilst in Hungary) but tested in manual which drives in UK

2. Other psychiatric problems which may have hindered driving

Two were actually unsafe, but predicted to be safe

This highlights the importance of clinician involvement

N B Lincoln - Spring 2009

Page 21: Nadina B Lincoln Jenny L Taylor Kristina Vella Walter P ... B Lincoln Jenny L Taylor Kristina Vella Walter P Bouman Kathryn A Radford. Background ... (Donnelly & Karlinsky 1990; BPS

Preliminary conclusionThe original equation was only moderately predictive in an independent sample

HOWEVER the battery of tests was still predictive

Further analysis is required to establish how best to combine these tests into a reliable predictive equation. 

N B Lincoln - Spring 2009

Page 22: Nadina B Lincoln Jenny L Taylor Kristina Vella Walter P ... B Lincoln Jenny L Taylor Kristina Vella Walter P Bouman Kathryn A Radford. Background ... (Donnelly & Karlinsky 1990; BPS

Practical ApplicationDiagnosed with dementia/licence for reviewCognitive Screening Assessment

Continue driving

Referred for on-road assessment at

Regional Mobility Centre

Score more than a select cut-off

Score less than a select cut-off

N B Lincoln - Spring 2009

Page 23: Nadina B Lincoln Jenny L Taylor Kristina Vella Walter P ... B Lincoln Jenny L Taylor Kristina Vella Walter P Bouman Kathryn A Radford. Background ... (Donnelly & Karlinsky 1990; BPS

For further [email protected]

Lincoln, N. B., Radford, K. A., Lee, E. & Reay, A. C. (2006) The assessment of fitness to drive in people with dementia. Int J Geriatr Psych, 21, 1044-1051.

N B Lincoln - Spring 2009


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