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Giorgia Mangili
C U R R I C U L U M V I T A E
PERSONAL INFORMATION
Name MANGILI GIORGIA
Address VIA OLGETTINA 60, 20132, MILAN ITALY
Telephone number 0226432653
E-mail [email protected]
Nationality Italian
Date of birth 09/10/1958
WORK EXPERIENCE
Dates (from - to) 9/2002 now Head, Gynecology Oncology Unit, Department of Obstetrics and Gynecology, IRCSS San Raffaele, Milan.
Dal 7/1992 9/2002 Medical Assistant, Department of Obstetrics and Gynecology, IRCSS San Raffaele, Milan.
2013Professor in gynecology and obstetrics – Residency in Obstetrics and Gynecology- Vita e Salute San Raffaele University
EDUCATION AND TRAINING
Dates (from - to) 2013 National qualification for associated professor in obstetrics and gynecology
1991. Residency in Oncology, University of Milan, Thesis: Borderline tumors of the ovary
1987 Residency in Gynecology and Obstetrics with full honours, University of Milan Thesis: Epithelial ovarian tumors
1983. MD with full honours, university of Milan Thesis: Gestational trophoblastic tumors
July, 1992 Visiting doctor (MD), Department of Medical Oncology, Charing Cross Hospital, London ( Director Prof. Newland), broading her knowledge of gestational trophoblastic tumors
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RESEARCH FIELDS / MAIN SCIENTIFIC INTERESTS
Gynecological oncology - oncofertility
Author and coauthor of scientific papers on gynecological national and international scientific journals
Author and coauthor of scientific books for medical students
Draft of guidelines in gynecological oncology
Invited speaker in several courses, lessons and seminars
Special attention has been paid to the training of students/ resident who choose gynaecological oncology as their graduation subject.
Professor in gynecology and obstetrics Vita e Salute San Raffaele University
Principal or Co-Investigator in several phase II-III trials and clinical research studies
conduced under GCP (Good Clinical Practice)
IMBO: “A phase II, multicentre, randomized controlled study evaluating the
quality of life in patients with inoperable malignant bowel obstruction
treated with lanreotide autogel 120 mg in combination with standard care vs.
standard care alone (QoL in IMBO study)”.
SOLO3: “A Phase III, Open Label, Randomised, Controlled, Multi-centre Study
to assess the efficacy and safety of Olaparib Monotherapy versus Physician’s
Choice Single Agent Chemotherapy in the Treatment of Platinum Sensitive
Relapsed Ovarian Cancer in Patients carrying germline BRCA1/2 Mutations”.
Morab 003-011: “A Randomized, Double-Blind, Placebo-Controlled, Phase 2
Study to Assess the Efficacy and Safety of Farletuzumab (MORAb-003) in
Combination with Carboplatin plus Paclitaxel or Carboplatin plus Pegylated
Liposomal Doxorubicin (PLD) in Subjects with Low CA125 Platinum-Sensitive
Ovarian Cancer”.
Alienor - ENGOT: “A randomized, open label, phase II trial of bevacizumab
plus weekly paclitaxel followed by bevacizumab monotherapy maintenance
versus weekly paclitaxel followed by observation in patients with relapsed
ovarian sex-cord stromal tumours”.
MITO 23: “Randomized phase III trial on Trabectedin (ET-743) vs clinician’s
choice chemotherapy in recurrent ovarian, primary peritoneal or fallopian
tube cancers of BRCA mutated or BRCAness phenotype patients”.
ARD6772 “Multicenter, open-label, single arm study of intravenous AVE0005
(VEGF trap) administered every 2 weeks in advanced ovarian cancer with
recurrent symptomatic malignant ascites
AGO-OVAR16/VEG110655: “A Phase III Study to Evaluate the Efficacy
and Safety of Pazopanib Monotherapy Versus Placebo inWomen Who
Have not Progressed after First Line Chemotherapy for Epithelial
Ovarian, Fallopian Tube, or Primary Peritoneal Cancer”.
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IP-CAT-AC-03: “ Two- arm, randomized, open-label,
phase IIIb study investigating the safety of a
3 hour i.p. infusion of catumaxomab with and without
prednisolone premedication in patients with malignant ascites
due to epithelial cancer.”
AGO-OVAR16/VEG110655: “A Phase III Study to Evaluate the Efficacy
and Safety of Pazopanib Monotherapy Versus Placebo in
Women Who Have not Progressed after
First Line Chemotherapy for Epithelial Ovarian, Fallopian Tube,
or Primary Peritoneal Cancer”.
AGO OVAR 16 “ Multicenter, randomized, double-blind Phase III trial to
investigate the efficacy and safety of BIBF 1120
in combination with carboplatin and paclitaxel compared to placebo
plus carboplatin and paclitaxel in patients with advanced ovarian cancer”.
NGR/IPR24:” Randomized phase II study of NGR-hTNF
plus pegylated liposomal doxorubicin (PLD) versus PLD
in platinum resistant ovarian cancer”.
MITO-16-MANGO-OV2 is a single arm, open-label, non comparative,
multicenter phase IV study
Grants
Investigator, “In vivo imaging of HMGB1-dependent spreading
of ovarian cancer”, PI Angelo Manfredi Granting Agency AIRC 2012-2014.
Co-principal investigator, progetto “Terapia intraperitoneale con
cellule dendritiche e linfociti NK in pazienti con carcinoma ovarico avanzato”
PI Marco Bregni Granting Agency Fondazione Berlucchi, 2006-2011
Preclinical study “study of the vascular damage induced by chemotherapy in
a mouse model – drug supply”
Membership
Member, European Gynecologic Cancer Society (ESGO)
Member, European Organization for treatment of Trophoblastic Disease
(EOTTD)
Board of directory, Società Italiana di Oncologia Ginecologica (SIGO), 2010-
2012
Società Italiana di Oncologia Ginecologica (SIOG)
Board of Directory, MITO GROUP "Multicenter Italian Trials in Ovarian cancer
and gynecologic malignancies and Referee for International relationship’s
commission (GCIG members), Responsible for Commission of rare tumors in
MITO
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Scientific publications (international indexed-PubMed)
A case of granulomatosis with polyangiitis: rheumatoid arthritis overlap syndrome presenting as cervical
cancer successfully treated with rituximab.
Campochiaro C, Scotti R, Margari S, Giorgione V, Mellone R, Mangili G, Del Maschio A, Tresoldi M.Intern Med
J. 2016 Jun;46(6):745-6. doi: 10.1111/imj.13090.
Mental Representations of Illness in Patients with Gestational Trophoblastic Disease: How Do Patients
Perceive Their Condition?
Di Mattei VE, Carnelli L, Mazzetti M, Bernardi M, Di Pierro R, Bergamini A, Mangili G, Candiani M, Sarno
L.PLoS One. 2016 Apr 21;11(4):e0153869. doi: 10.1371/journal.pone.0153869. eCollection 2016.
Chemotherapy-Induced Nausea and Vomiting in Women With Gynecological Cancer: A Preliminary Single-
Center Study Investigating Medical and Psychosocial Risk Factors.
Di Mattei VE, Carnelli L, Carrara L, Bernardi M, Crespi G, Rancoita PM, Bergamini A, Petrone M, Ritella C,
Rabaiotti E, Mangili G.Cancer Nurs. 2016 Feb 18. [Epub ahead of print]
[18F]fluorodeoxyglucose positron emission tomography/computed tomography and trophoblastic disease:
the gynecologist perspective.
Mangili G, Bergamini A, Giorgione V, Picchio M, Petrone M, Mapelli P, Rabaiotti E, Incerti E, Candiani M.Q J
Nucl Med Mol Imaging. 2016 Jun;60(2):103-16. Epub 2016 Feb 11.
[Gestational Trophoblastic Disease: psychological impact and the role of defence mechanisms during illness
and follow-up].
Di Mattei VE, Mazzetti M, Carnelli L, Bernardi M, Di Pierro R, Bergamini A, Giorgione V, Mangili G.
Recenti Prog Med. 2015 Dec;106(12):641-5. doi: 10.1701/2094.22658. Italian.
Reply to "Hysteroscopic Resection in Fertility-Sparing Surgery for Atypical Hyperplasia and Endometrial
Cancer: How Important Are Intrauterine Adhesions?".
De Marzi P, Bergamini A, Luchini S, Petrone M, Taccagni G, Mangili G, Colombo G, Candiani M.
J Minim Invasive Gynecol. 2016 Mar-Apr;23(3):454-5. doi: 10.1016/j.jmig.2015.12.007. Epub 2015 Dec 24. No
abstract available.
Female fertility preserving practices at a pediatric unit: a challenge of multiprofessional and multidisciplinary
cooperation.
Terenziani M, Meazza C, Massimino M, Viganò P, Gandola L, Mangili G, Raspagliesi F, Biasoni D, Podda M,
Veneroni L, Filippi F, Riccipetitoni G, Somigliana E.
Tumori. 2016 Apr 18;102(2):174-7. doi: 10.5301/tj.5000452. Epub 2015 Dec 17.
Prospective phase II trial of trabectedin in BRCA-mutated and/or BRCAness phenotype recurrent ovarian
cancer patients: the MITO 15 trial.
Lorusso D, Scambia G, Pignata S, Sorio R, Amadio G, Lepori S, Mosconi A, Pisano C, Mangili G, Maltese G,
Sabbatini R, Artioli G, Gamucci T, Di Napoli M, Capoluongo E, Ludovini V, Raspagliesi F, Ferrandina G.Ann
Oncol. 2016 Mar;27(3):487-93. doi: 10.1093/annonc/mdv608. Epub 2015 Dec 17.
Standard first-line chemotherapy with or without nintedanib for advanced ovarian cancer (AGO-OVAR 12): a
randomised, double-blind, placebo-controlled phase 3 trial.
du Bois A, Kristensen G, Ray-Coquard I, Reuss A, Pignata S, Colombo N, Denison U, Vergote I, Del Campo JM,
Ottevanger P, Heubner M, Minarik T, Sevin E, de Gregorio N, Bidziński M, Pfisterer J, Malander S, Hilpert F,
Mirza MR, Scambia G, Meier W, Nicoletto MO, Bjørge L, Lortholary A, Sailer MO, Merger M, Harter P; AGO
Study Group led Gynecologic Cancer Intergroup/European Network of Gynaecologic Oncology Trials Groups
Intergroup Consortium.
Lancet Oncol. 2016 Jan;17(1):78-89. doi: 10.1016/S1470-2045(15)00366-6. Epub 2015 Nov 16.
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A systematic review on endometriosis during pregnancy: diagnosis, misdiagnosis, complications and
outcomes.
Leone Roberti Maggiore U, Ferrero S, Mangili G, Bergamini A, Inversetti A, Giorgione V, Viganò P, Candiani
M.Hum Reprod Update. 2016 Jan-Feb;22(1):70-103. doi: 10.1093/humupd/dmv045. Epub 2015 Oct 7.
A case of pre-eclampsia and foetal growth restriction after embolisation for a postmolar uterine
arteriovenous malformation.
Giorgione V, Inversetti A, Cavoretto P, Valsecchi L, Mangili G, De Cobelli F, Lucianò R, Pasi F, Candiani M.J
Obstet Gynaecol. 2016;36(1):68-9. doi: 10.3109/01443615.2015.1036413. Epub 2015 Oct 2. No
Reply to "Hysteroscopic Resection in Fertility-Sparing Surgery for Atypical Hyperplasia and Endometrial
Cancer: How Important are Intrauterine Adhesions?".
De Marzi P, Bergamini A, Luchini S, Petrone M, Taccagni G, Mangili G, Colombo G, Candiani M.
J Minim Invasive Gynecol. 2015 Nov-Dec;22(7):1319. doi: 10.1016/j.jmig.2015.07.010. Epub 2015 Jul 20.
Hysteroscopic Resection in Fertility-Sparing Surgery for Atypical Hyperplasia and Endometrial Cancer: Safety
and Efficacy.
De Marzi P, Bergamini A, Luchini S, Petrone M, Taccagni GL, Mangili G, Colombo G, Candiani M.
J Minim Invasive Gynecol. 2015 Nov-Dec;22(7):1178-82. doi: 10.1016/j.jmig.2015.06.004. Epub 2015 Jun 16.
An investigative study into psychological and fertility sequelae of gestational trophoblastic disease: the
impact on patients' perceived fertility, anxiety and depression.
Di Mattei VE, Carnelli L, Bernardi M, Pagani Bagliacca E, Zucchi P, Lavezzari L, Giorgione V, Ambrosi A, Mangili
G, Candiani M, Sarno L.
PLoS One. 2015 Jun 1;10(6):e0128354. doi: 10.1371/journal.pone.0128354. eCollection 2015.
Different Patterns of Disease Spread between Advanced-Stage Type I and II Epithelial Ovarian Cancer.
Bergamini A, Candiani M, Taccagni G, Rabaiotti E, Viganò R, De Marzi P, Ferrari D, Mangili G.
Gynecol Obstet Invest. 2016;81(1):10-4. doi: 10.1159/000381261. Epub 2015 Apr 22.
Investigational therapies currently in Phase II clinical trials for the treatment of pelvic serous carcinomas.
Bergamini A, Leone Roberti Maggiore U, Ferrero S, Rabaiotti E, Viganò R, Petrone M, De Marzi P, Salvatore S,
Candiani M, Mangili G.
Expert Opin Investig Drugs. 2015 Mar;24(3):345-62. doi: 10.1517/13543784.2015.999154. Epub 2015 Feb 1.
Review.
Management of bilateral malignant ovarian germ cell tumors: a MITO-9 retrospective study.
Sigismondi C, Scollo P, Ferrandina G, Candiani M, Angioli R, Viganò R, Scarfone G, Mangili G.
Int J Gynecol Cancer. 2015 Feb;25(2):203-7. doi: 10.1097/IGC.0000000000000358.
Fertility preservation in female cancer patients: a single center experience.
Sigismondi C, Papaleo E, Viganò P, Vailati S, Candiani M, Ottolina J, Di Mattei VE, Mangili G.
Chin J Cancer. 2015 Jan;34(1):56-60. doi: 10.5732/cjc.014.10252.
Is the endometrial evaluation routinely required in patients with adult granulosa cell tumors of the ovary?
Ottolina J, Ferrandina G, Gadducci A, Scollo P, Lorusso D, Giorda G, Breda E, Savarese A, Candiani M, Zullo
F, Mangili G.
Gynecol Oncol. 2015 Feb;136(2):230-4. doi: 10.1016/j.ygyno.2014.12.016. Epub 2014 Dec 17.
Gynecologic Cancer InterGroup (GCIG) consensus review for high-grade undifferentiated sarcomas of the
uterus.
Pautier P, Nam EJ, Provencher DM, Hamilton AL, Mangili G, Siddiqui NA, Westermann AM, Reed NS, Harter P,
Ray-Coquard I.
Int J Gynecol Cancer. 2014 Nov;24(9 Suppl 3):S73-7. doi: 10.1097/IGC.0000000000000281. Review.
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Gynecologic Cancer InterGroup (GCIG) consensus review for mucinous ovarian carcinoma.
Ledermann JA, Luvero D, Shafer A, O'Connor D, Mangili G, Friedlander M, Pfisterer J, Mirza MR, Kim JW,
Alexandre J, Oza A, Brown J.
Int J Gynecol Cancer. 2014 Nov;24(9 Suppl 3):S14-9. doi: 10.1097/IGC.0000000000000296. Review.
Trophoblastic disease review for diagnosis and management: a joint report from the International Society for
the Study of Trophoblastic Disease, European Organisation for the Treatment of Trophoblastic Disease, and
the Gynecologic Cancer InterGroup.
Mangili G, Lorusso D, Brown J, Pfisterer J, Massuger L, Vaughan M, Ngan HY, Golfier F, Sekharan PK, Charry
RC, Poveda A, Kim JW, Xiang Y, Berkowtiz R, Seckl MJ.
Int J Gynecol Cancer. 2014 Nov;24(9 Suppl 3):S109-16. doi: 10.1097/IGC.0000000000000294. Review.
Gestational trophoblastic disease: psychological aspects and fertility issues.
Di Mattei VE, Carnelli L, Ambrosi A, Mangili G, Candiani M, Sarno L.
J Reprod Med. 2014 Sep-Oct;59(9-10):488-95.
Potential role of raltegravir-based therapy to induce rapid viral decay in highly viraemic HIV-infected
neonates.
Ripamonti D, Tatarelli P, Mangili G, Gotta C, Benatti SV, Bruzzone B, Callegaro A, Viscoli C, Ruggeri M, Biagio
AD.
J Chemother. 2014 Sep 24:1973947814Y0000000217. [Epub ahead of print]
Management of endometrial cancer in Italy: a national survey endorsed by the Italian Society of Gynecologic
Oncology.
Greggi S, Franchi M, Aletti G, Biglia N, Ditto A, Fagotti A, Giorda G, Mangili G, Odicino F, Salerno MG, Vizza E,
Scaffa C, Scollo P.
Int J Surg. 2014 Oct;12(10):1038-44. doi: 10.1016/j.ijsu.2014.08.356. Epub 2014 Aug 20.
Surveillance policy for stage IA malignant ovarian germ cell tumors in children and young adults.
Mangili G, Sigismondi C, Lorusso D, Pignata S.
J Clin Oncol. 2014 Sep 1;32(25):2814-5. doi: 10.1200/JCO.2014.55.9617. Epub 2014 Jul 28. No abstract
available.
Reproductive function assessment after surgery plus chemotherapy for germ cell ovarian tumors (MOGCT):
novel clues deriving from the field of fertility preservation.
Ottolina J, Mangili G, Sigismondi C, Vanni VS, Viganò P, Candiani M.
Gynecol Endocrinol. 2014 Nov;30(11):778-80. doi: 10.3109/09513590.2014.943724. Epub 2014 Jul 18.
Characteristics of clear cell ovarian cancer arising from endometriosis: a two center cohort study.
Scarfone G, Bergamini A, Noli S, Villa A, Cipriani S, Taccagni G, Vigano' P, Candiani M, Parazzini F,Mangili G.
Gynecol Oncol. 2014 Jun;133(3):480-4. doi: 10.1016/j.ygyno.2014.03.017. Epub 2014 Mar 15.
Hyperreactio luteinalis: timely diagnosis minimizes the risk of oophorectomy and alerts clinicians to the
associated risk of placental insufficiency.
Cavoretto P, Giorgione V, Sigismondi C, Mangili G, Serafini A, Dallagiovanna C, Candiani M.
Eur J Obstet Gynecol Reprod Biol. 2014 May;176:10-6. doi: 10.1016/j.ejogrb.2014.02.017. Epub 2014 Feb 21.
Review.
Endometriosis-associated tumor at the inguinal site: report of a case diagnosed during pregnancy and
literature review.
Bergamini A, Almirante G, Taccagni G, Mangili G, Viganò P, Candiani M.
J Obstet Gynaecol Res. 2014 Apr;40(4):1132-6. doi: 10.1111/jog.12310. Epub 2014 Mar 10. Review.
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Hydatidiform mole: age-related clinical presentation and high rate of severe complications in older women.
Mangili G, Giorgione V, Gentile C, Bergamini A, Pella F, Almirante G, Candiani M.
Acta Obstet Gynecol Scand. 2014 May;93(5):503-7. doi: 10.1111/aogs.12357. Epub 2014 Mar 20.
Surgical treatment of elderly patients with endometrial cancer (≥ 65 years).
De Marzi P, Ottolina J, Mangili G, Rabaiotti E, Ferrari D, Viganò R, Candiani M.
J Geriatr Oncol. 2013 Oct;4(4):368-73. doi: 10.1016/j.jgo.2013.07.001. Epub 2013 Aug 1.
Secondary analyses from a randomized clinical trial: age as the key prognostic factor in endometrial
carcinoma.
Benedetti Panici P, Basile S, Salerno MG, Di Donato V, Marchetti C, Perniola G, Palagiano A, Perutelli A,
Maneschi F, Lissoni AA, Signorelli M, Scambia G, Tateo S, Mangili G, Katsaros D, Campagnutta E, Donadello N,
Greggi S, Melpignano M, Raspagliesi F, Cormio G, Grassi R, Franchi M, Giannarelli D, Fossati R, Torri V, Crocè
C, Mangioni C.
Am J Obstet Gynecol. 2014 Apr;210(4):363.e1-363.e10. doi: 10.1016/j.ajog.2013.12.025. Epub 2013 Dec 19.
Treatment with anticancer agents induces dysregulation of specific Wnt signaling pathways in human ovarian
luteinized granulosa cells in vitro.
Sanchez AM, Giorgione V, Viganò P, Papaleo E, Candiani M, Mangili G, Panina-Bordignon P.
Toxicol Sci. 2013 Nov;136(1):183-92. doi: 10.1093/toxsci/kft175. Epub 2013 Aug 16.
Long-term follow-up is crucial after treatment for granulosa cell tumours of the ovary.
Mangili G, Ottolina J, Gadducci A, Giorda G, Breda E, Savarese A, Candiani M, Frigerio L, Scarfone G, Pignata S,
Rossi R, Marinaccio M, Lorusso D.
Br J Cancer. 2013 Jul 9;109(1):29-34. doi: 10.1038/bjc.2013.241. Epub 2013 Jun 11.
Comparison of optimal cytoreduction rates in emergency versus non-emergency admissions for advanced
ovarian cancer: a multi-institutional study.
Mangili G, Scambia G, Ottolina J, Fanfani F, Viganò R, Costantini B, Candiani M, Fagotti A.
Eur J Surg Oncol. 2013 Aug;39(8):906-11. doi: 10.1016/j.ejso.2013.05.011. Epub 2013 Jun 5.
Recurrent granulosa cell tumors (GCTs) of the ovary: a MITO-9 retrospective study.
Mangili G, Sigismondi C, Frigerio L, Candiani M, Savarese A, Giorda G, Lauria R, Tamberi S, Greggi S, Lorusso D.
Gynecol Oncol. 2013 Jul;130(1):38-42. doi: 10.1016/j.ygyno.2013.04.047. Epub 2013 Apr 25.
Role of 18F-FDG PET in the management of gestational trophoblastic neoplasia.
Mapelli P, Mangili G, Picchio M, Gentile C, Rabaiotti E, Giorgione V, Spinapolice EG, Gianolli L, Messa C,
Candiani M.
Eur J Nucl Med Mol Imaging. 2013 Apr;40(4):505-13. doi: 10.1007/s00259-012-2324-4. Epub 2013 Jan 12.
Sarcoidosis mimicking metastatic gynaecological malignancies: a diagnostic and therapeutic challenge?
Mapelli P, Mangili G, Picchio M, Rabaiotti E, Gianolli L, Messa C, Candiani M.
Rev Esp Med Nucl Imagen Mol. 2013 Sep-Oct;32(5):314-7. doi: 10.1016/j.remn.2012.11.001. Epub 2012 Dec
25.
Clear cell and papillary serous endometrial carcinomas: survival in a series of 128 cases.
Scarfone G, Secomandi R, Parazzini F, Viganò R, Mangili G, Frigerio L, Villa A, Tateo S, Ricci E, Bolis G.
Arch Gynecol Obstet. 2013 Feb;287(2):351-6. doi: 10.1007/s00404-012-2586-x. Epub 2012 Oct 26.
Phase II study of NGR-hTNF in combination with doxorubicin in relapsed ovarian cancer patients.
Lorusso D, Scambia G, Amadio G, di Legge A, Pietragalla A, De Vincenzo R, Masciullo V, Di Stefano M, Mangili
G, Citterio G, Mantori M, Lambiase A, Bordignon C.
Br J Cancer. 2012 Jun 26;107(1):37-42. doi: 10.1038/bjc.2012.233. Epub 2012 May 29.
Unraveling the two entities of endometrioid ovarian cancer: a single center clinical experience.
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Mangili G, Bergamini A, Taccagni G, Gentile C, Panina P, Viganò P, Candiani M.
Gynecol Oncol. 2012 Sep;126(3):403-7. doi: 10.1016/j.ygyno.2012.05.007. Epub 2012 May 15.
Ovarian Sertoli-Leydig cell tumors. a retrospective MITO study.
Sigismondi C, Gadducci A, Lorusso D, Candiani M, Breda E, Raspagliesi F, Cormio G, Marinaccio M,Mangili G.
Gynecol Oncol. 2012 Jun;125(3):673-6. doi: 10.1016/j.ygyno.2012.03.024. Epub 2012 Mar 22.
Temporal trends in the frequency of hydatidiform mole in lombardy, northern Italy, 1996-2008.
Parazzini F, Ricci E, Cipriani S, Bulfoni G, Mangili G, Chiaffarino F.
Int J Gynecol Cancer. 2012 Feb;22(2):318-22. doi: 10.1097/IGC.0b013e31823b3504.
Transvaginal ultrasound predicts delayed response to chemotherapy and drug resistance in stage I low-risk
trophoblastic neoplasia.
Cavoretto P, Gentile C, Mangili G, Garavaglia E, Valsecchi L, Spagnolo D, Montoli S, Candiani M.
Ultrasound Obstet Gynecol. 2012 Jul;40(1):99-105. doi: 10.1002/uog.11097.
A phase II study of aflibercept in patients with advanced epithelial ovarian cancer and symptomatic malignant
ascites.
Colombo N, Mangili G, Mammoliti S, Kalling M, Tholander B, Sternas L, Buzenet G, Chamberlain D.
Gynecol Oncol. 2012 Apr;125(1):42-7. doi: 10.1016/j.ygyno.2011.11.021. Epub 2011 Nov 21.
Use of adjuvant therapy in patients with FIGO stage III endometrial carcinoma: a multicenter retrospective
study.
Marchetti C, Pisano C, Mangili G, Lorusso D, Panici PB, Silvestro G, Candiani M, Greggi S, Perniola G, Di Maio
M, Pignata S.
Oncology. 2011;81(2):104-12. doi: 10.1159/000331677. Epub 2011 Oct 4.
Outcome and risk factors for recurrence in malignant ovarian germ cell tumors: a MITO-9 retrospective study.
Mangili G, Sigismondi C, Gadducci A, Cormio G, Scollo P, Tateo S, Ferrandina G, Greggi S, Candiani M, Lorusso
D.
Int J Gynecol Cancer. 2011 Nov;21(8):1414-21. doi: 10.1097/IGC.0b013e3182236582.
Treatment of recurrent or metastatic low-grade endometrial stromal sarcoma: three case reports.
Garavaglia E, Pella F, Montoli S, Voci C, Taccagni G, Mangili G.
Int J Gynecol Cancer. 2010 Oct;20(7):1197-200.
Uterine papillary serous, clear cell, and poorly differentiated endometrioid carcinomas: a comparative study.
Greggi S, Mangili G, Scaffa C, Scala F, Losito S, Iodice F, Pisano C, Montoli S, Viganò R, Pirozzi G, Giannarelli D.
Int J Gynecol Cancer. 2011 May;21(4):661-7. doi: 10.1097/IGC.0b013e3182150c89.
Is surgical restaging indicated in apparent stage IA pure ovarian dysgerminoma? The MITO group
retrospective experience.
Mangili G, Sigismondi C, Lorusso D, Cormio G, Scollo P, Viganò R, Gamucci T, Candiani M, Pignata S.
Gynecol Oncol. 2011 May 1;121(2):280-4. doi: 10.1016/j.ygyno.2011.01.006. Epub 2011 Jan 28.
Management of locally advanced cervical cancer in pregnancy: a case report.
Rabaiotti E, Sigismondi C, Montoli S, Mangili G, Candiani M, Viganò R.
Tumori. 2010 Jul-Aug;96(4):623-6.
Paclitaxel/carboplatin versus topotecan/paclitaxel/carboplatin in patients with FIGO suboptimally resected
stage III-IV epithelial ovarian cancer a multicenter, randomized study.
Bolis G, Scarfone G, Raspagliesi F, Mangili G, Danese S, Scollo P, Lo Russo D, Villa A, Aimone PD, Scambia G.
Eur J Cancer. 2010 Nov;46(16):2905-12. doi: 10.1016/j.ejca.2010.06.124. Epub 2010 Jul 29.
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Is adjuvant chemotherapy indicated in stage I pure immature ovarian teratoma (IT)? A multicentre Italian trial
in ovarian cancer (MITO-9).
Mangili G, Scarfone G, Gadducci A, Sigismondi C, Ferrandina G, Scibilia G, Viganò R, Tateo S, Villa A, Lorusso D.
Gynecol Oncol. 2010 Oct;119(1):48-52. doi: 10.1016/j.ygyno.2010.05.035.
High-grade endometrial cancer: value of [(18)F]FDG PET/CT in preoperative staging.
Picchio M, Mangili G, Samanes Gajate AM, De Marzi P, Spinapolice EG, Mapelli P, Giovacchini G, Sigismondi C,
Viganò R, Sironi S, Messa C.
Nucl Med Commun. 2010 Jun;31(6):506-12. doi: 10.1097/MNM.0b013e328337cb47.
Surgery in advanced borderline tumors.
Viganò R, Petrone M, Pella F, Rabaiotti E, De Marzi P, Mangili G.
Fertil Steril. 2010 Aug;94(3):1163-5. doi: 10.1016/j.fertnstert.2009.11.033. Epub 2009 Dec 29.
.
Adjuvant treatment with concomitant radiotherapy and chemotherapy in high-risk endometrial cancer: a
clinical experience.
De Marzi P, Frigerio L, Cipriani S, Parazzini F, Busci L, Carlini L, Viganò R, Mangili G.
Gynecol Oncol. 2010 Mar;116(3):408-12. doi: 10.1016/j.ygyno.2009.11.019. Epub 2009 Dec 21.
Role of the integrated FDG PET/CT in the surgical management of patients with high risk clinical early stage
endometrial cancer: detection of pelvic nodal metastases.
Signorelli M, Guerra L, Buda A, Picchio M, Mangili G, Dell'Anna T, Sironi S, Messa C.
Gynecol Oncol. 2009 Nov;115(2):231-5. doi: 10.1016/j.ygyno.2009.07.020. Epub 2009 Aug 19.
Positron emission tomography/computed tomography introduction in the clinical management of patients
with suspected recurrence of ovarian cancer: a cost-effectiveness analysis.
Mansueto M, Grimaldi A, Mangili G, Picchio M, Giovacchini G, Viganò R, Messa C, Fazio F.
Eur J Cancer Care (Engl). 2009 Nov;18(6):612-9. doi: 10.1111/j.1365-2354.2008.00945.x. Epub 2009 Jun 22.
Ultrasound imaging after evacuation as an adjunct to beta-hCG monitoring in posthydatidiform molar
gestational trophoblastic neoplasia.
Garavaglia E, Gentile C, Cavoretto P, Spagnolo D, Valsecchi L, Mangili G.
Am J Obstet Gynecol. 2009 Apr;200(4):417.e1-5. doi: 10.1016/j.ajog.2008.11.032. Epub 2009 Feb 6.
Systematic pelvic lymphadenectomy vs. no lymphadenectomy in early-stage endometrial carcinoma:
randomized clinical trial.
Benedetti Panici P, Basile S, Maneschi F, Alberto Lissoni A, Signorelli M, Scambia G, Angioli R, Tateo S, Mangili
G, Katsaros D, Garozzo G, Campagnutta E, Donadello N, Greggi S, Melpignano M, Raspagliesi F, Ragni N,
Cormio G, Grassi R, Franchi M, Giannarelli D, Fossati R, Torri V, Amoroso M, Crocè C, Mangioni C.
J Natl Cancer Inst. 2008 Dec 3;100(23):1707-16. doi: 10.1093/jnci/djn397. Epub 2008 Nov 25.
Activity of chemotherapy in mucinous ovarian cancer with a recurrence free interval of more than 6 months:
results from the SOCRATES retrospective study.
Pignata S, Ferrandina G, Scarfone G, Scollo P, Odicino F, Cormio G, Katsaros D, Villa A, Mereu L, Ghezzi F,
Manzione L, Lauria R, Breda E, Alletti DG, Ballardini M, Lombardi AV, Sorio R, Mangili G, Priolo D, Magni G,
Morabito A.
BMC Cancer. 2008 Sep 1;8:252. doi: 10.1186/1471-2407-8-252.
Phase III randomised study to evaluate the role of adjuvant pelvic radiotherapy in the treatment of uterine
sarcomas stages I and II: an European Organisation for Research and Treatment of Cancer Gynaecological
Cancer Group Study (protocol 55874).
Reed NS, Mangioni C, Malmström H, Scarfone G, Poveda A, Pecorelli S, Tateo S, Franchi M, Jobsen JJ, Coens C,
Teodorovic I, Vergote I, Vermorken JB; European Organisation for Research and Treatment of Cancer
Gynaecological Cancer Group.
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Eur J Cancer. 2008 Apr;44(6):808-18. doi: 10.1016/j.ejca.2008.01.019. Epub 2008 Apr 2. Erratum in: Eur J
Cancer. 2008 Jul;44(11):1612.
The role of DNA ploidy in postoperative management of stage I endometrial cancer.
Mangili G, Montoli S, De Marzi P, Sassi I, Aletti G, Aletti G, Taccagni G.
Ann Oncol. 2008 Jul;19(7):1278-83. doi: 10.1093/annonc/mdn041. Epub 2008 Mar 19.
Clinical presentation of hydatidiform mole in northern Italy: has it changed in the last 20 years?
Mangili G, Garavaglia E, Cavoretto P, Gentile C, Scarfone G, Rabaiotti E.
Am J Obstet Gynecol. 2008 Mar;198(3):302.e1-4. doi: 10.1016/j.ajog.2007.09.036. Epub 2008 Feb 21. Review.
Prevention strategies in palmar-plantar erythrodysesthesia onset: the role of regional cooling.
Mangili G, Petrone M, Gentile C, De Marzi P, Viganò R, Rabaiotti E.
Gynecol Oncol. 2008 Feb;108(2):332-5.
Integrated PET/CT as a first-line re-staging modality in patients with suspected recurrence of ovarian cancer.
Mangili G, Picchio M, Sironi S, Viganò R, Rabaiotti E, Bornaghi D, Bettinardi V, Crivellaro C, Messa C, Fazio F.
Eur J Nucl Med Mol Imaging. 2007 May;34(5):658-66. Epub 2006 Dec 20.
Paclitaxel and concomitant radiotherapy in high-risk endometrial cancer patients: preliminary findings.
Mangili G, De Marzi P, Beatrice S, Rabaiotti E, Viganò R, Frigerio L, Gentile C, Fazio F.
BMC Cancer. 2006 Jul 25;6:198.
Palliative care for intestinal obstruction in recurrent ovarian cancer: a multivariate analysis.
Mangili G, Aletti G, Frigerio L, Franchi M, Panacci N, Viganò R, DE Marzi P, Zanetto F, Ferrari A.
Int J Gynecol Cancer. 2005 Sep-Oct;15(5):830-5.
Primary stage I-IIE non-Hodgkin's lymphoma of uterine cervix and upper vagina: evidence for a conservative
approach in a study on three patients.
Garavaglia E, Taccagni G, Montoli S, Panacci N, Ponzoni M, Frigerio L, Mangili G.
Gynecol Oncol. 2005 Apr;97(1):214-8.
Integrated FDG PET/CT in patients with persistent ovarian cancer: correlation with histologic findings.
Sironi S, Messa C, Mangili G, Zangheri B, Aletti G, Garavaglia E, Vigano R, Picchio M, Taccagni G, Maschio AD,
Fazio F.
Radiology. 2004 Nov;233(2):433-40.
Paclitaxel 175 or 225 mg per meters squared with carboplatin in advanced ovarian cancer: a randomized trial.
Bolis G, Scarfone G, Polverino G, Raspagliesi F, Tateo S, Richiardi G, Melpignano M, Franchi M,Mangili G,
Presti M, Villa A, Conta E, Guarnerio P, Cipriani S, Parazzini F.
J Clin Oncol. 2004 Feb 15;22(4):686-90.
An unusual admixture of neoplastic and metaplastic lesions of the female genital tract in the Peutz-Jeghers
Syndrome.
Mangili G, Taccagni G, Garavaglia E, Carnelli M, Montoli S.
Gynecol Oncol. 2004 Jan;92(1):337-42.
[18F]fluorodeoxyglucose positron emission tomography as a useful indicator of metastatic gestational
trophoblastic tumor: preliminary results in three patients.
Sironi S, Picchio M, Mangili G, Garavaglia E, Zangheri B, Messa C, Voci C, Taccagni GL, del Maschio A, Fazio F.
Gynecol Oncol. 2003 Oct;91(1):226
Advanced ovarian carcinoma: usefulness of [(18)F]FDG-PET in combination with CT for lesion detection after
primary treatment.
Picchio M, Sironi S, Messa C, Mangili G, Landoni C, Gianolli L, Zangheri B, Viganò R, Aletti G, De Marzi P, De
Cobelli F, Del Maschio A, Ferrari A, Fazio F.
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Q J Nucl Med. 2003 Jun;47(2):77-84.
Cisplatin, doxorubicin and ifosfamide in carcinosarcoma of the female genital tract. A phase II study of the
European Organization for Research and Treatment of Cancer Gynaecological Cancer Group (EORTC 55923).
van Rijswijk RE, Vermorken JB, Reed N, Favalli G, Mendiola C, Zanaboni F, Mangili G, Vergote I, Guastalla JP,
ten Bokkel Huinink WW, Lacave AJ, Bonnefoi H, Tumulo S, Rietbroek R, Teodorovic I, Coens C, Pecorelli S.
Eur J Cancer. 2003 Mar;39(4):481-7.
Oral contraceptives and risk of gestational trophoblastic disease.
Parazzini F, Cipriani S, Mangili G, Garavaglia E, Guarnerio P, Ricci E, Benzi G, Salerio B, Polverino G, La Vecchia
C.
Contraception. 2002 Jun;65(6):425-7.
Identification of high risk patients with endometrial carcinoma. Prognostic assessment of endometrial cancer.
Mangili G, De Marzi P, Viganò R, Rabaiotti E, Sassi I, Taccagni GL, Garancini P, Frigerio L.
Eur J Gynaecol Oncol. 2002;23(3):216-20.
A multicentre collaborative study on the use of cold scalpel and electrocautery for midline abdominal
incision.
Franchi M, Ghezzi F, Benedetti-Panici PL, Melpignano M, Fallo L, Tateo S, Maggi R, Scambia G,Mangili G,
Buttarelli M.
Am J Surg. 2001 Feb;181(2):128-32.
Metastatic placental site trophoblastic tumor. Report of a case with complete response to chemotherapy.
Mangili G, Garavaglia E, De Marzi P, Zanetto F, Taccagni G.
J Reprod Med. 2001 Mar;46(3):259-62.
Concomitant radiotherapy and paclitaxel for high-risk endometrial cancer: first feasibility study.
Frigerio L, Mangili G, Aletti G, Carnelli M, Garavaglia E, Beatrice S, Ferrari A.
Gynecol Oncol. 2001 Apr;81(1):53-7.
Carboplatin alone vs carboplatin plus epidoxorubicin as second-line therapy for cisplatin- or carboplatin-
sensitive ovarian cancer.
Bolis G, Scarfone G, Giardina G, Villa A, Mangili G, Melpignano M, Presti M, Tateo S, Franchi M, Parazzini F;
Associazione per la Ricerca in Ginecologia Oncologia (ARGO 96) Study Group.
Gynecol Oncol. 2001 Apr;81(1):3-9.
Response and toxicity to topotecan in sensitive ovarian cancer cases with small residual disease after first-line
treatment with carboplatinum and paclitaxel.
Bolis G, Scarfone G, Tateo S, Mangili G, Villa A, Parazzini F.
Gynecol Oncol. 2001 Jan;80(1):13-5.
Diagnosis of persistent ovarian carcinoma with three-step immunoscintigraphy.
Magnani P, Fazio F, Grana C, Songini C, Frigerio L, Pecorelli S, Mangili G, Colombo N, Mariani CD, Paganelli G.
Br J Cancer. 2000 Feb;82(3):616-20.
Hashimoto's disease in a papillary carcinoma of the thyroid originating in a teratoma of the ovary (malignant
struma ovarii).
Doldi N, Taccagni GL, Bassan M, Frigerio L, Mangili G, Jansen AM, Ferrari A.
Gynecol Endocrinol. 1998 Feb;12(1):41-2.
Reliability of preoperative evaluation of prognostic factors in endometrial carcinoma.
Valsecchi L, Mangili G, Frigerio L, Spagnolo DL, De Sanctis L, Ferrari A.
Int J Gynaecol Obstet. 1997 Oct;59(1):35-9.
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Weekly cisplatin given for 2 months versus cisplatin plus cyclophosphamide given for 5 months after
cytoreductive surgery for advanced ovarian cancer.
Bolis G, Favalli G, Danese S, Zanaboni F, Mangili G, Scarabelli C, Tateo S, Valsecchi MG, Scarfone G, Richiardi
G, Frigerio L, Melpignano M, Villa A, Parazzini F.
J Clin Oncol. 1997 May;15(5):1938-44.
Idiopathic sclerosing peritonitis associated with florid mesothelial hyperplasia, ovarian fibromatosis, and
endometriosis: a new disorder of abdominal mass.
Frigerio L, Taccagni GL, Mariani A, Mangili G, Ferrari A.
Am J Obstet Gynecol. 1997 Mar;176(3):721-2.
Octreotide in the management of bowel obstruction in terminal ovarian cancer.
Mangili G, Franchi M, Mariani A, Zanaboni F, Rabaiotti E, Frigerio L, Bolis PF, Ferrari A.
Gynecol Oncol. 1996 Jun;61(3):345-8.
Management of low-risk gestational trophoblastic tumors with etoposide (VP16) in patients resistant to
methotrexate.
Mangili G, Garavaglia E, Frigerio L, Candotti G, Ferrari A.
Gynecol Oncol. 1996 May;61(2):218-20.
Gestational choriocarcinoma metastatic to the brain treated successfully by stereotactic radiosurgery and
chemotherapy.
Leslie MD, Mangili G, Kemeny AA, Newlands ES.
Clin Oncol (R Coll Radiol). 1996;8(4):259-60.
Adjuvant treatment for early epithelial ovarian cancer: results of two randomised clinical trials comparing
cisplatin to no further treatment or chromic phosphate (32P). G.I.C.O.G.: Gruppo Interregionale Collaborativo
in Ginecologia Oncologica.
Bolis G, Colombo N, Pecorelli S, Torri V, Marsoni S, Bonazzi C, Chiari S, Favalli G, Mangili G, Presti M, et al.
Ann Oncol. 1995 Nov;6(9):887-93.
Transvaginal ultrasonography in persistent trophoblastic tumor.
Mangili G, Spagnolo D, Valsecchi L, Maggi R.
Am J Obstet Gynecol. 1993 Nov;169(5):1218-23.
Repeated gestational trophoblastic disease after natural and heterologous assisted conception. A case report.
Mangili G, Parazzini F, Maggi R, Spolti N.
J Reprod Med. 1993 May;38(5):405-6.
Risk factors for gestational trophoblastic disease: a separate analysis of complete and partial hydatidiform
moles.
Parazzini F, Mangili G, La Vecchia C, Negri E, Bocciolone L, Fasoli M.
Obstet Gynecol. 1991 Dec;78(6):1039-45.
[Immunobiology of vesicular mole and choriocarcinoma].
Mangili G, Illeni MT, Spolti N, Lombardo C, Bruno L, Maggi R.
Ann Ostet Ginecol Med Perinat. 1990 Sep-Oct;111(5):326-31. Italian.
[Primary carcinoma of the fallopian tube: cases from 1971 to 1985 (27 patients). Current therapeutic
approaches].
Bortolozzi G, Frigoli A, Maggi R, Arnoletti E, Garsia S, Mangili G.
Ann Ostet Ginecol Med Perinat. 1989 Jan-Feb;110(1):7-14. Review. Italian.
EMA/CO regimen in high-risk gestational trophoblastic tumor (GTT).
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Bolis G, Bonazzi C, Landoni F, Mangili G, Vergadoro F, Zanaboni F, Mangioni C.
Gynecol Oncol. 1988 Nov;31(3):439-44.
The problem of identification of prognostic factors for persistent trophoblastic disease.
Parazzini F, Mangili G, Belloni C, La Vecchia C, Liati P, Marabini R.
Gynecol Oncol. 1988 May;30(1):57-62.
Analysis of 309 cases after hydatidiform mole: different follow-up program according to biologic behavior.
Bolis G, Belloni C, Bonazzi C, Mangili G, Presti M, Zanaboni F, Mangioni C.
Tumori. 1988 Feb 29;74(1):93-6.
Dietary factors and risk of trophoblastic disease.
Parazzini F, La Vecchia C, Mangili G, Caminiti C, Negri E, Cecchetti G, Fasoli M.
Am J Obstet Gynecol. 1988 Jan;158(1):93-9.
[Histological aspects of endometrial epithelium ranging between atrophy and adenocarcinoma].
Carinelli SG, Merlo D, Cefis F, Pintucci JP, Vergani S, Gasparotto GC, Frigoli A, Mangili G, Benzi G, Ferrari A.
Ann Ostet Ginecol Med Perinat. 1987 Sep-Oct;108(5):281-303. Italian. No abstract available
Methotrexate with citrovorum factor in low-risk gestational trophoblastic tumor.
Bolis G, Colombo N, Epis A, Mangili G, Vassena L, Vergadoro F, Belloni C.
Tumori. 1987 Jun 30;73(3):309-13.
[Lymphatic complications in the therapy of clinical cervix carcinoma. Cases of the decade from 1971 to 1980
(1157 patients)].
Bortolozzi G, Mangili G, Raimondo V, Uderzo A, Zanetta M.
Ann Ostet Ginecol Med Perinat. 1986 Sep-Oct;107(5):296-304. Italian. No abstract available.
ABO blood-groups and the risk of gestational trophoblastic disease.
Parazzini F, La Vecchia C, Franceschi S, Pampallona S, Decarli A, Mangili G, Belloni C.
Tumori. 1985 Apr 30;71(2):123-6.
.
Familial trophoblastic disease: case report.
Parazzini F, La Vecchia C, Franceschi S, Mangili G.
Am J Obstet Gynecol. 1984 Jun 15;149(4):382-3.
Possible ways of helping terminal patients.
Maggioni C, Benzi G, Belloni C, Mangili G, Candiani GB.
Eur J Gynaecol Oncol. 1984;5(1):21-5.
