CNISP PCSINCNISP PCSINCNISP PCSIN
National Antibiotic Resistant Organism (ARO) Infection Rates in Canadian Acute Care Hospitals participating in the Canadian Nosocomial Infection Surveillance Program (CNISP)
Staphylococcus aureus (S. aureus) bacteria that are resistant to the antibiotic methicillin
are known as Methicillin-resistant Staphylococcus aureus (MRSA). MRSA can cause bloodstream, skin and soft tissue, bone and lung infections, and left untreated, they can be life-threatening.
Vancomycin-resistant Enterococci (VRE) are strains of enterococci bacteria that are resistant to the antibiotic vancomycin, an antibiotic generally prescribed to treat serious infections. VRE can cause infections such as urinary tract, surgical site and bloodstream infections.
Gram-negative bacilli (GNB) cause a variety of infections, such as urinary tract, pneumonia and serious bloodstream or wound infections. GNB that have acquired resistance to carbapenems are called carbapenem-resistant gram-negative
(CRGN) bacilli. Carbapenemase-producing Enterobacteriaceae (CPE) are a subset of CRGN bacilli which produce an enzyme that inactivates carbapenems, a last resort antibiotic.
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0.05
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0.25
2012 2013 2014 2015 2016
Rat
e pe
r 10
,000
pat
ient
day
s
0.00 0.10 0.20 0.30 0.40 0.50 0.60 0.70 0.80 0.90 1.00
2012 2013 2014 2015 2016
0.0
0.5
1.0
1.5
2.0
2.5
3.0
3.5
4.0
2012 2013 2014 2015 2016
0.0
1.0
2.0
3.0
4.0
5.0
6.0
7.0
8.0
2012 2013 2014 2015 2016
Rat
e pe
r 10
,000
pat
ient
day
s R
ate
per
10,0
00 p
atie
nt d
ays
West Central East National
West Central East National
West Central East National
West Central East National
VRE INFECTION RATES PER 10,000 PATIENT DAYS
CPE INFECTION RATES PER 10,000 PATIENT DAYS
MRSA INFECTION RATES PER 10,000 PATIENT DAYS
HA-CDI RATES PER 10,000 PATIENT DAYS
Rat
e pe
r 10
,000
pat
ient
day
s
0.00
0.05
0.10
0.15
0.20
0.25
2012 2013 2014 2015 2016
Rat
e pe
r 10
,000
pat
ient
day
s
0.00 0.10 0.20 0.30 0.40 0.50 0.60 0.70 0.80 0.90 1.00
2012 2013 2014 2015 2016
0.0
0.5
1.0
1.5
2.0
2.5
3.0
3.5
4.0
2012 2013 2014 2015 2016
0.0
1.0
2.0
3.0
4.0
5.0
6.0
7.0
8.0
2012 2013 2014 2015 2016
Rat
e pe
r 10
,000
pat
ient
day
s R
ate
per
10,0
00 p
atie
nt d
ays
West Central East National
West Central East National
West Central East National
West Central East National
VRE INFECTION RATES PER 10,000 PATIENT DAYS
CPE INFECTION RATES PER 10,000 PATIENT DAYS
MRSA INFECTION RATES PER 10,000 PATIENT DAYS
HA-CDI RATES PER 10,000 PATIENT DAYS
Rat
e pe
r 10
,000
pat
ient
day
s
0.00
0.05
0.10
0.15
0.20
0.25
2012 2013 2014 2015 2016
Rat
e pe
r 10
,000
pat
ient
day
s
0.00 0.10 0.20 0.30 0.40 0.50 0.60 0.70 0.80 0.90 1.00
2012 2013 2014 2015 2016
0.0
0.5
1.0
1.5
2.0
2.5
3.0
3.5
4.0
2012 2013 2014 2015 2016
0.0
1.0
2.0
3.0
4.0
5.0
6.0
7.0
8.0
2012 2013 2014 2015 2016
Rat
e pe
r 10
,000
pat
ient
day
s R
ate
per
10,0
00 p
atie
nt d
ays
West Central East National
West Central East National
West Central East National
West Central East National
VRE INFECTION RATES PER 10,000 PATIENT DAYS
CPE INFECTION RATES PER 10,000 PATIENT DAYS
MRSA INFECTION RATES PER 10,000 PATIENT DAYS
HA-CDI RATES PER 10,000 PATIENT DAYS
Rat
e pe
r 10
,000
pat
ient
day
s
0.00
0.05
0.10
0.15
0.20
0.25
2012 2013 2014 2015 2016
Rat
e pe
r 10
,000
pat
ient
day
s
0.00 0.10 0.20 0.30 0.40 0.50 0.60 0.70 0.80 0.90 1.00
2012 2013 2014 2015 2016
0.0
0.5
1.0
1.5
2.0
2.5
3.0
3.5
4.0
2012 2013 2014 2015 2016
0.0
1.0
2.0
3.0
4.0
5.0
6.0
7.0
8.0
2012 2013 2014 2015 2016
Rat
e pe
r 10
,000
pat
ient
day
s R
ate
per
10,0
00 p
atie
nt d
ays
West Central East National
West Central East National
West Central East National
West Central East National
VRE INFECTION RATES PER 10,000 PATIENT DAYS
CPE INFECTION RATES PER 10,000 PATIENT DAYS
MRSA INFECTION RATES PER 10,000 PATIENT DAYS
HA-CDI RATES PER 10,000 PATIENT DAYS
Rat
e pe
r 10
,000
pat
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s
MRSA
VRE
CPE
Clostridium difficile (C. difficile) is a bacterium that causes diarrhea
and is the most common cause of infectious diarrhea in hospital settings. Hospital-associated C. difficile infection (HA-CDI) can lead to complications requiring surgery or death.
Adult or Mixed Adult/Pediatric HospitalsPediatric Hospitals
HA-CDI
Geographic Location of CNISP Hospitals
MRSA
HA-CDI
CPE
VRE
Infection prevention and control measures play a crucial role in helping to prevent the spread of these resistant organisms in healthcare settings.