SPECIAL HEALTH REPORT
The question many middle-aged people ask is why they keep
accumulating body fat when they’re eating far less than they did
when they were younger. Scientists have identified a number of
biological factors to explain age-related weight gain. And therein
lies the problem. With so many causes at work, it’s far more
difficult to lose that extra weight than most of us realize.
The good news is that there are now more weight-loss compounds
available to neutralize those factors than ever before. And in
controlled clinical studies, each of those natural compounds has
demonstrated modest to impressive fat-loss effects. But the trick
here is to combine them in a multi-pronged program to circumvent
multiple factors involved in excess age-related fat storage.
So let’s take a look at some of the factors that make you fat and
keep you fat … and how you can effectively neutralize them.
Burn fat better. It’s a fact. As you age, cellular energy
expenditure slows. Instead of burning fat effectively to be used as
energy, you store more of it in your fat cells (adipocytes). And
scientists have found that this decrease in energy expenditure may
cause 120–190 excess calories to be stored in the body every day1 …
which translates to an extra 13–20 pounds of stored body fat each
year!
Natural Approaches For
Life Extension Foundation®
For more than 32 years, the Life Extension Foundation has sought to
help people like you live healthier longer. To that end, we’ve
spent over $100 million on innovative anti-aging research, and made
it our business to provide our members with products, services, and
information to help them make better health decisions.
Based on the research we fund and the information we report, we’ve
formulated some 350 different premium-quality, science-based
nutritional supplements to help you achieve and maintain optimal
health … and assembled an integrative team of Health Advisors to
help you in customizing personal regimens of diet, exercise, and
nutritional supplements.
With our help you can feel younger, stay healthier, and live
longer. So call a Life Extension® Health Advisor at 1-800-226-2370
to get started today.
According to a number of published studies, one way to increase fat
burning is by supplementing with green tea extracts. The key
components responsible for green tea’s weight- loss benefits are
polyphenol compounds that increase metabolic energy expenditure …
so you burn more calories.2-6
A unique green tea phytosome tested on human subjects demonstrated
rapid and substantial weight loss effects. After 45 days, the
control group using only a restricted calorie diet and no
supplements lost four pounds on average … while the group
supplementing with green tea lost 13 pounds on average. And after
90 days, the control group lost 9.9 pounds, while the green tea
group shed 30.1 pounds.7 In addition, those receiving the green tea
dropped their BMI (body mass index) by a whopping 12% (compared to
5% in the control group)7… and reduced their waist sizes by 10%
(compared to 5% in the control group).7
But the weight loss benefits of green tea extracts don’t stop at
fat burning. Green tea polyphenols have also been shown to inhibit
the breakdown and absorption of fat in the digestive tract and to
reduce fat storage in fat cells.2,8-10
Overcome leptin resistance. Leptin is a hormone produced by fat
cells that helps keep your body lean. It works by signaling your
brain to turn off hunger messages because you’ve eaten enough.
Leptin also increases the breakdown of fat stored in fat cells, so
it can be burned as energy.
Now, as we age, our cells (including the appetite control center in
our brains) become leptin-resistant. That means that leptin is no
longer able to effectively regulate body weight.
Leptin resistance is a chronic inflammatory condition that
contributes directly to progressive weight gain, makes it harder to
lose weight, and ensures that you’re bound to regain any weight you
do lose. Extra weight that puts you at increased risk for diabetes,
heart disease, cancer, a stroke,11 even dementia.12
Being chronically overweight leads to chronically elevated leptin
levels, and chronically elevated leptin causes fat cells and brain
neurons to lose their capacity to respond to it. So normal fat
burning within fat cells declines significantly and neurons in the
hypothalamus show decreased responsiveness to leptin. 13
So what can you do to correct this Catch-22? Well, for starters,
exercise
more regularly; avoid high-sugar, high fat, highly processed foods;
and supplement with irvingia African mango extract … which tends to
correct leptin resistance, facilitate the breakdown of stored body
fat, and help keep the carbs you eat from being broken down and
absorbed. In short, irvingia promotes weight loss along with some
pretty healthy side benefits.
In fact, in a double-blind study, overweight people who
supplemented with irvingia extract lost over 25 pounds on average
in 10 weeks.14 Their body fat percentage dropped over 18% on
average and their waistlines decreased over 6 inches on average.14
Their cholesterol, LDL, C-reactive protein, and fasting glucose
levels also dropped.
It’s no wonder that the local tribes of West Africa, who have
included the cooked fruit of this mango plant in their daily diets
for centuries, are comprised of pretty lean and healthy folk!
Trim that belly fat. Unfortunately, with age our fat cells tend to
expand and congregate in areas that are both unsightly and
unhealthy. Of greatest concern are the fat storage cells deep in
the abdomen. This “visceral fat” represents more than just
belly
fat stored around the waist. Visceral fat is chemically active
tissue that churns out a torrent of pro-inflammatory cytokines15
that trigger metabolic syndrome (also known as “pre-diabetes”) and
its deadly consequences.16,17
This widespread problem led scientists to seek out plant extracts
that specifically interfere with the storage of fat in abdominal
fat cells. It was found that blending the extracts of the flower S.
indicus and the mangosteen fruit (both native to Asia) inhibited
fat storage and enhanced fat breakdown and release … thus promoting
weight loss three ways. This phyto-blend prevented young fat cells
from maturing. It reduced the amount of
fat that could be stored. And it sped up the breakdown of fat
already stored in existing fat cells.
In a human weight loss study of 60 obese adults, 30 were given 800
mg a day of this dual plant extract while the other 30 were given a
placebo. Both groups followed a 2,000 calorie-per-day diet and were
asked to walk for 30 minutes five times a week. After eight weeks,
the group taking this natural blend lost 11.4 pounds (3.7 times
greater than the placebo group) and 4.05 inches of harmful belly
fat (two times more than the placebo group).18
In a second similar study,19 the results were virtually the same …
validating yet again the weight
loss and health benefits of supplementation with this natural
phyto-blend.
Lower your blood sugar to shed extra pounds. There is extensive
evidence that a high level of coffee consumption lowers the risk of
type 2 diabetes by 67%.20 The reason for this anti-diabetic effect
appears to be reduced levels of blood glucose, increased insulin
sensitivity, and decreased storage of fat and carbohydrate. All
achieved with chlorogenic acid, the compound in green coffee beans
that inhibits both the absorption of glucose21 and the enzyme that
breaks down starch into sugar.9
Clearly the less sugar you absorb, the less sugar your body will
convert to fat. So reducing glucose
levels leads to a decrease in intestinal calorie uptake.22,
23
Chlorogenic acid also reduces dangerous after-meal glucose spikes
that can last hours or even a whole day.24 That lowers insulin
activity and fat accumulation.25
In a placebo-controlled human study of extremely overweight
individuals, 350 mg of a green coffee bean extract high in
chlorogenic acid ingested 3 times daily for 12 weeks induced weight
loss of over 17.6 pounds on average … with some participants losing
more than 22 pounds!23 And 37% of the participants involved
reversed their status back to the normal weight range!23 These
results confirm that green coffee bean extract is another unique
and potent intervention for weight loss.
Additional Resources for Your Review:
Reduce Blood Glucose and Shed Pounds Fast!, Life Extension
Magazine®, July 2012
Shed Pounds by Inhibiting Cellular Fat Storage, Life Extension
Magazine®, July 2011
Critical Need for Multi-Modal Approach to Combat Obesity, Life
Extension Magazine®, June 2009
Understanding the Risks of Leptin Resistance, Life Extension
Magazine®, February 2009
Online Magazine Articles
References: 1. Eur J Clin Nutr. 2006 Jan;60(1):18-24. 2. Drug Metab
Dispos. 2003 May;31(5):572-9. 3. Biochem Pharmacol. 2005 May
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Jan;292(1):R77-R85. 5. Int J Obes Relat Metab Disord. 2000
Feb;24(2):252-8. 6. J Nutr. 2009 Feb;139(2):264-70. 7. Integr Nutr.
2008;11(2):1-14. 8. Asia Pac J Clin Nutr. 2008;17 Suppl
1:273-4. 9. Food Funct. 2011 Feb;2(2):111-6. Epub 2011 Jan 4.
10. Mol Nutr Food Res. 2009 Mar;53(3):349-60. 11. Curr Diab Rep.
2008 Feb;8(1):37-41. 12. JAMA. 2004 Nov 10;292(18):2237-42. 13.
Cell Metab. 2012 Feb 8;15(2):137-49. Epub 2012
Jan 11. 14. Lipids Health Dis. 2009 Mar 2;8:7. 15. Nippon
Yakurigaku Zasshi. 2001 Nov;118(5):315-20. 16. Exp Biol Med
(Maywood). 2010 Dec;235(12):1442-9. 17. J Nutr. 2010
Apr;140(4):842-71.
But this is only the beginning.
Now that you’ve become a Life Extension member, the real learning
begins.
So take the next step.
Call a Life Extension Health Advisor now at 1-800-226-2370
toll-free. Find out what you need to be taking ... and ask for a
free copy of the comprehensive Life Extension Weight Loss
Guide.
www.LifeExtension.com
18. FASEB J. April 2011; 25:(Meeting Abstract Supple- ment) 601.9.
Presented at Experimental Biology 2011, Washington, DC. April 10,
2011. Program No. 601.9, Poster No. A278.
19. Results based on initial analyses of unpublished research
data.
20. Nutr Metab Cardiovasc Dis. 2011 Jun;21(6):418-23. 21. Am J Clin
Nutr. 2003 Oct;78(4):728-33. 22. J Agric Food Chem.
2009;57:9218-25. 23. Andrologia. 2008 Dec;40(6):398-400. 24.
Appl Physiol Nutr Metab. 2011 Oct;36(5):650-9. 25. Diabetologia.
2011 Feb;54(2):320-8.