Nehal N. Mehta, MD, MSCE, FAHA Page 1 Curriculum Vitae Nehal...

Nehal N. Mehta, MD, MSCE, FAHA Page 1

National Institutes of Health, National Heart, Lung, and Blood Institute

Curriculum Vitae

Date: 11/6/2014

Nehal N. Mehta, MD, MSCE, FAHA

Address: 10 Center Drive

CRC, Room 5-5140

National Institutes of Health

Bethesda, MD 20892 USA

Phone: 301-824-0483

Fax: 301-451-7093

Email: [email protected]

Education:

1997 BA The George Washington University (Seven-Year Accelerated

Medical Program) (Neuropsychobiology)

1997 NA Oxford University (Biochemistry)

2001 MD The George Washington University Medical School

(Medicine)

2009 MSCE University of Pennsylvania, Center for Clinical Epidemiology

and Biostatistics (Genetic Epidemiology)

Postgraduate Training and Fellowship Appointments:

2001-2002 Internship in Internal Medicine, Hospital of University of

Pennsylvania

2002-2004 Residency in Internal Medicine, Hospital of University of

Pennsylvania

2004-2005 Chief Medical Resident, Hospital of the University of

Pennsylvania

2005-2007 Fellow in Cardiovascular Medicine, Hospital of the University

of Pennsylvania

2006-2007 Chief Fellow in Cardiovascular Medicine, Hospital of the

University of Pennsylvania

2007-2009 Post-doctoral Research Fellow in Cardiovascular

Medicine/Fellow in Genetic Epidemiology, Center for Clinical

Biostatistics and Epidemiology, University of Pennsylvania

2007 Course on Genetics of Diabetes, Columbia University

2007 Course on Complex Heart, Lung and Blood Disorders, The

Jackson Laboratory

2007 Course on Clinical Cardiovascular Genomics, Cold Spring

Harbor

2008 Cohort Study Conference on Cardiac Diseases, National Heart,

Lung and Blood Institute

mailto:[email protected]


Faculty Appointments:

2004-2005 Clinical Instructor in Medicine, University of Pennsylvania

School of Medicine

2009-2012 Instructor A in Cardiovascular Medicine, University of

Pennsylvania School of Medicine

2009-present Adjunct Scholar, Center for Clinical Biostatistics and

Epidemiology, University of Pennsylvania School of Medicine

2012-present Adjunct Assistant Professor, University of Pennsylvania

School of Medicine

2013-present

2014-present

Clinical Associate Professor of Medicine, The George

Washington University School of Medicine and Health

Sciences

Clinical Professor of Medicine, The George Washington

University School of Medicine and Health Sciences

Hospital and/or Administrative Appointments:

2007-2012 Attending Physician, Division of Cardiology, Pennsylvania

Hospital

2008-2012 Attending Cardiologist, Pennsylvania Hospital, University of

Pennsylvania

2008-2012 Director, Cardiology Advanced Practitioner Services

2009-2012 Attending Cardiologist, Hospital of the University of

Pennsylvania

2009-present Director, Inflammatory Risk, Preventive Cardiology, Hospital

of the University of Pennsylvania

2012-present Chief, Section of Inflammation and Cardiometabolic Diseases,

Cardiovascular and Pulmonary Branch, National Heart, Lung,

and Blood Institute, National Institutes of Health

Specialty Certification:

2004 American Board of Internal Medicine (Internal Medicine)

2007 National Board of Echocardiography (Level II

Echocardiography)

2007 American Society of Nuclear Cardiology (Nuclear

Cardiology)

2008 American Board of Internal Medicine (Cardiovascular

Diseases)

Licensure:

2005-Present Pennsylvania State Board of Medicine

Awards, Honors and Membership in Honorary Societies:

1991 Eagle Scouts of America Award

1995 National Collegiate Scholar

1996 Psi Chi Psychology Honors Society, The George Washington

University


1996 Phi Beta Kappa, The George Washington University

1997 Summa Cum Laude, The George Washington University

1997 Hertford College Scholar Award, Oxford University

1998 WT Gill Research Fellowship, The George Washington

University

2000 William Beaumont Research Honors Society, The George

Washington University

2001 Kane King Dodek Obstetrical Honors Society The George

Washington University

2001 MD with Distinction, The George Washington University

2005 Edward W. Holmes Resident Research Award, Hospital of the


2006 American College of Cardiology/Merck Award for Metabolic

Syndrome Research

2006 Basic Science Teaching Award - Best Section Leader,

University of Pennsylvania School of Medicine

2007 Nominee, Best Section Leader, University Of Pennsylvania

School of Medicine

2007 Fellow, American College of Physicians

2008 Junior Investigators Pilot Grant Award, University of

Pennsylvania Clinical Translational Research Center

2008 Finalist, Northwestern University Young Investigators Forum

2008 Fellow, American College of Cardiology

2008 Fellow Research Award, Division of Cardiovascular

Medicine, Penn Cardiovascular Institute

2009 Best abstract, Gordon Conference on Atherosclerosis

2009 Future Leader in Cardiovascular Research Award

2009 Leadership Council in Cardiovascular Medicine National

Research Award (declined due to K23)

2009 Fellow, American Heart Association

2009 Dr. Madhukar Deshmukh Research Award, Best Abstract

Clinical Research in Preventive Cardiology, American

Association of Cardiologists of Indian Origin

2009 First Prize, Northwestern University Young Investigators

Forum, Best Clinical Research

2010 Jeremiah Stammler Research Award, Northwestern University

Young Investigators Symposium, Best Faculty Research

2010 Bradley Award, Best Young Investigator, Junior Faculty,

Department of Medicine, University of Pennsylvania

2012

2014

Lasker Clinical Research Scholar Award, The National

Institutes of Health, National Heart, Lung, and Blood Institute

IPC Councilor, International Psoriasis Council

Memberships in Professional and Scientific Societies and Other Professional Activities:

National:

1997-Present American Medical Association (Member)


1999-Present American College of Physicians (Member (1999-present); Fellow (2007-present)

2004-Present American Heart Association Council on Prevention/Epidemiology (Member); Chair,

Early Career Committee (2010-2012)

2005-Present American College of Cardiology (Fellow)

2005-Present American Society of Echocardiography (Member)

2007-Present American Society of Nuclear Cardiology (Member)

2010-Present American Heart Association Awards & Lectures Committee (Member)

2011-Present

2014-Present

2014-Present

2014-2016

2014-Present

American Heart Association Research Committee (Member)

European Society for Translational Medicine (Member)

National Psoriasis Foundation (NPF) Medical Board (Member)

American Heart Association Awards & Lectures Committee (Chair)

American College of Cardiology ACC.15 Program Committee (Member)

Local:

1997-2001 Medical Society of Washington DC (Member)

2001-2012 Pennsylvania Medical Society (Member)

Reviewer/Editorial Positions:

2005-Present Editorial Staff, First Aid Clinical Cases, Cardiovascular Series

2006-Present Reviewer, Journal of the Cardiometabolic Syndrome

2006-Present Reviewer, International Journal of Cardiology

2006-Present Reviewer, Circulation

2006-Present Reviewer, American Journal of Cardiology

2006-Present Consulting Editor, Handheld Books, Cardiovascular Series

2008-Present Reviewer, Journal of American College of Cardiology

2008-Present Reviewer, Journal of Pharmacoepidemiology

2009-Present Reviewer, J of European Acad of Derm and Venereology

2009-Present Reviewer, Journal of Rheumatology

2009-Present Reviewer, Journal of Obesity

2009-Present Reviewer, Circulation CV Genetics

2009-Present Reviewer, PLoS One

2010-Present Reviewer, British Journal of Dermatology

2010-Present Reviewer, Abstracts of the American Heart Association

2010-Present Reviewer, Abstracts of the American College of Cardiology

2010-Present Reviewer, Atherosclerosis

2010-Present Reviewer, British Medical Journal

2010-Present Reviewer, American Heart Journal

2011-Present Reviewer, Journal of Clinical Lipidology

2011-Present Reviewer, JAMA

2011-Present Reviewer, Abstracts of the AHA Epidemiology Meeting

2011-Present Associate Editor, BMC Cardiovascular Diseases

2011-Present Associate Editor, Journal of Cardiovascular Diseases

2012-Present

Section Editor, Journal of Translational Medicine, Section of

Cardiovascular, Lipoprotein and Metabolic Translation

2012-Present Editorial Board Member, Heart Insight Magazine


2012-Present

2012

2013 Abstract Reviewer, American Heart Association:

Epidemiology and Prevention/Nutrition, Physical Activity and

Metabolism Scientific Sessions (EPI/NPAM)

Reviewer, ACC.14 Program Committee

2013

2013 National Psoriasis Foundation Discovery and Translational

Grant Application Reviewer

2013 Editorial Board Member, JSM Genetics and Genomics, Journal of

Immunology & Clinical Research

2013

2013-2015

2013-present

2013-present

2013-present

2013-present

2014-present

2014-present

2014-present

2014-present

2014-present

2014-present

2014-present

2014-present

2014-present

2014-present

2014-present

2014-present

Reviewer, American Heart Association’s Genomics & Translational

Epidemiology & Observational Epidemiology – Population Science

1 Peer Review Committee, Fall 2013

Epidemiology & Prevention Council’s Prevention Science

Committee (Member)

Editorial Board Member, Insights of Translational Medicine

Editorial Board Member, World Journal of Cardiology

Editorial Board Member, Austin Journal of Immunology

Editorial Board Member, Journal of Cardiology and Therapy

Editorial Board Member, Journal of Geriatric Cardiology

Grant reviewer, The Netherlands Organization for Health Research

and Development (ZonMw)

Editorial Board Member, International Scholarly Research Notices

Editorial Board Member, International Journal of Cardiology and

Research

Editorial Board Member, Insight Knowledge

Reviewer, American Heart Association for Strategically Focused

Network on Prevention

Editorial Board Member, Journal of Experimental Dermatology and

Clinical Research

Editorial Board Member, Journal of Medical Genomics and

Biomarkers (MGB)

Editorial Board Member, American College of Cardiology

Prevention Clinical Topic Collection

Editorial Board Member, Global Journal of Obesity, Diabetes, and

Metabolic Syndrome

Editorial Board Member, Journal of Immunology and

Immunotherapeutics

Editorial Board Member, CYTOKINE

Academic and Institutional Committees:

2001-2002 Intern Steering Committee, Department of Medicine, Hospital of the


2002-2005 Resident Steering Committee, Department of Medicine, Hospital of

the University of Pennsylvania

2008-Present Director, Cardiology Advanced Practitioner Service


Major Academic and Clinical Teaching Responsibilities:

2000-2001 Clinical instructor to 1st and 2nd year students in physical

examination and history taking.

2000 Internal Medicine Curriculum Committee representative to develop

clinical skills; reviewed a chest x-ray class and EKG class.

2001 EKG reading skills workshop for the 3rd year clinical clerks.

2002 Department of Medical Genetics Grand Rounds, University of

Pennsylvania, Conference on Hereditary Hemorrhagic

Telangiectasia, "Pulmonary Venous Aneurysms Detected by Time-

Resolved MRA"

2002 EKG digitizer for medical resident and cardiovascular fellow

conferences under Ralph Verdino, MD.

2004-2012 Lecturer, Department of Ob/Gyn, peri-operative cardiac diseases

2004-2005 Chief Medical Resident, Hospital of the University of Pennsylvania

2005 Department of Medicine Grand Rounds, University of Pennsylvania.

"38th Tri-annual Chief Medical Resident Clinical Pathological

Conference"

2005 Division of Cardiology and Cardiothoracic Surgery, University of

Pennsylvania. "Massive Pericardial Effusion 3 months after aortic

root surgery"

2005-2012 Medical student clinical cardiovascular auscultation seminar,

"Harvey", School of Medicine, University of Pennsylvania


Pennsylvania. "Atrioventricular Septal Defect"


Pennsylvania. "Ischemic mitral regurgitation"


Pennsylvania. "Management of Malignant Pericardial Effusion"

2006-2012 Small-group leader for 14 lectures yearly, Basic Science

Cardiovascular Module, School of Medicine, University of

Pennsylvania

2010-2012 Small-group leader, Penn Epidemiology course, first-year medical

students

Lectures by Invitation:

Jun, 2005 "Training at the Hospital of the University of Pennsylvania: Why

cardiology?", Penn Medicine Board of Trustees; Philadelphia, PA

Jun, 2005 "Adiposity and pro-atherosclerotic responses to an Innate Immune

Challenges in Humans", University of Pennsylvania Holmes

Research Day; Philadelphia, PA

Apr, 2006 "Modulation of the Insulin Signaling Pathway in Human

Inflammation", Atherosclerosis, Thrombosis and Vascular Biology

of the American Heart Association; Denver CO

Nov, 2006 "The Effect of PKC-Inhibition on Macrovascular Function in

Patients with Type 2 Diabetes", American Heart Association;

Chicago IL


Jun, 2007 "Understanding Diabetic Coronary Risk", Atlantic United Coder and

Abstracter Conference Keynote Speaker; Philadelphia, PA.

Nov, 2007 "Very-low Dose Endotoxemia Induces Insulin Resistance in the

Absence of Clinical Inflammatory Responses", American Heart

Association; Orlando FL

Jun, 2008 "Diabetic Coronary Disease and Complications", Atlantic City

Medical Center Medical Grand Rounds; Atlantic City, NJ

Mar, 2009 "Human Translational Studies of a Novel Atherosclerosis Locus",

Future Leaders of Cardiovascular Research; Orlando, FL

Jun, 2009 "A novel GWAS Atherosclerosis Locus Regulates Plasma CXCL12

levels", Gordon Conference on Atherosclerosis; Tilton NH

Jun, 2009 "Management of Cardiac Disease in Impaired Glucose Tolerance",

Atlantic City Medical Center Medical Grand Rounds; Atlantic City,

NJ

Oct, 2009 "Human Translational Studies of Inflammation, Insulin Resistance

and Atherosclerosis", Cardiovascular Medicine Grand Rounds;

Philadelphia PA

Oct, 2009 "Human Translational Studies of Inflammation, Psoriasis and

Atherosclerosis", The Murdough Symposium on Psoriasis, Case

Western University; Cleveland OH

Oct, 2009 "Psoriasis and Cardiovascular Care: An Innovative and Integrated

Approach to Risk Stratification and Risk Reduction", Murdough

Symposium on Psoriasis, Cleveland OH

Nov, 2009 "A novel GWAS Atherosclerosis Locus Regulates Plasma CXCL12

levels", American Heart Association' Orlando FL

Feb, 2010 "Human Translational Studies of CXCL12", Cardiovascular

Institute, University of Pennsylvania, Philadelphia PA

Sep, 2010 "Convergence of CXCL12 and PHACTR-1: Novel GWAS Signals

for MI", Northwestern Young Investigators Forum, Chicago, IL

Sep, 2010 "Cardiovascular Care of Patients with Psoriasis", Case Western

University Murdough Symposium, Cleveland, OH

Oct, 2010 "Genomic Variation, Inflammation and Vascular Disease",

Inflammation Symposium, University of Medicine and Dentistry of

New Jersey, Newark, NJ

Nov, 2010 "Convergence of CXCL12 and PHACTR-1: Novel GWAS Signals

for MI", Amaerican Heart Association Young Investigator Award

Finalist, Chicago, IL

Mar, 2011 "Evidence Based Practice of Advanced Inflammatory and

Lipoprotein Testing", American Occupational Medicine Conference,

Washington, DC

Jun, 2011 "Detection of Subclinical Systemic and Vascular Inflammation in

Psoriasis using FDG PET/CT", Division of Division of

Allergy/Immunology, Rheumatology and Department of

Dermatology (AIR) Grand Rounds, SUNY Rochester, Rochester,

NY


Jun, 2011 "FDG PET/CT Detects Vascular Inflammation in Vivo in Psoriasis",

Updates in Dermatology, New York University Department of

Dermatology, New York, NY

Jun, 2011 "In Vivo Modulation of CXCL12 in Adipose and Plasma", Gordon

Conference on Atherosclerosis, Newport, RI

Sept, 2011 “Human Translational Studies of Inflammation and Cardiometabolic

Diseases”, Lasker Scholar Seminar, National Institutes of Health

Oct, 2011 "Human Translational Studies of Inflammation and Atherosclerosis:

From Epidemiology and Back", Johns Hopkins University Welch

Center Grand Rounds, Baltimore, MD

Jul, 2012 “Psoriasis and Cardiovascular Risk”, Dermatology Resident Grand

Rounds, National Navy Medical Center, Bethesda, MD

Sept, 2012

Oct, 2012

Oct, 2012

Jan, 2013

“Advanced Cardiometabolic Phenotyping in Psoriasis: Links

between Psoriasis and CV Risk”, World Psoriasis Congress,

Stockholm, Sweden

“Understanding Psoriasis: Why a Cardiologist”, National Psoriasis

Foundation, Bethesda Country Club, Bethesda, MD

“Human Translational Studies of Inflammation and Cardiometabolic

Diseases: From Epidemiology and Back”, Extramural NHLBI,

Bethesda, MD

“Inflammation and Cardiometabolic Diseases: Associative or

Causal”, George Washington University CV Grand Rounds,

Washington, DC


Jan, 2013

Jan, 2013

Jan, 2013

Jan, 2013

Feb, 2013

Mar, 2013

Mar, 2013

Mar, 2013

Apr, 2013

Apr, 2013

Jun, 2013

Jun, 2013

Jun, 2013

Jul, 2013

“Human Translation of Inflammation and Cardiovascular Disease”,

George Washington University Grand Rounds, Washington, DC


Diseases: In Vivo Studies and Beyond”, Weekly Inflammation and

Immunity Seminar Series, Center for Cancer Research, Frederick,

MD


Disease”, Eli Lilly and Company, Indianapolis, IN


Disease”, Novartis Pharmaceuticals Co., East Hanover, NJ


Disease”, Johns Hopkins University Dermatology Grand Rounds,

Baltimore, MD

“A Comparison of Vascular Inflammation in Rheumatoid Arthritis,

Psoriasis and Healthy Controls by FDG-PET/CT: A Pilot Study,”

American College of Cardiology 62nd

Annual Scientific Session, San

Francisco, CA


Disease”, University of Maryland Dermatology Grand Rounds,

College Park, MD


Disease”, Baylor University Dermatology Grand Rounds, Dallas,

TX


Disease”, George Washington University Nephrology Grand

Rounds, Washington, DC


Disease”, NEDS Didactic Symposium, University of Connecticut

Health Center Department of Dermatology, Farmington, CT


Disease”, Case Western University, Cleveland, OH


Disease”, Cardiovascular Imaging Research Seminar, University of

Pennsylvania, Philadelphia, PA

“Psoriasis and Cardiometabolic Disease: Inflammation at the Heart

of the Matter?”, Canadian Dermatology Association 2013 Annual

Meeting, Toronto, CA


Disease”, Visiting Professor, Northwestern University Department

of Dermatology Grand Rounds, Chicago, IL


Jul, 2013

Jul, 2013

Sept, 2013

Oct, 2013

Nov, 2013

Feb, 2014

Feb, 2014

March, 2014

April, 2014

June, 2014

Keynote Speaker, NHLBI K Award Investigator’s Meeting,

Bethesda, MD

Persistent Inflammation and Immune Activation in HIV-Infected

Children and Youth on Effective ART, NICHD Offices, NIH,

Rockville, MD

Pennsylvania Regional Occupational Medicine Meeting,

Philadelphia, PA

Androgen Excess Meeting, Newport, RI

Key Note: “Inflammation and Cardiometabolic Diseases”,

International Psoriasis Council, Boston, MA

“Inflammation and Cardiometabolic Diseases: An Attempt to

Dissect Causality and Association”, University of Michigan Grand

Rounds, Ann Arbor, MI

National Institute of Arthritis and Musculoskeletal and Skin

Diseases Fellows talk

"Impact of psoriasis severity on hypertension control: a population-

based study in the United Kingdom", American Academy of

Dermatology Meeting, Denver, CO

“Inflammation and Cardiometabolic Diseases: An Attempt to

Dissect Causality and Association”, University of Pittsburgh

Medical Center Grand Rounds, Pittsburgh, PA

“Incidence of Major Adverse Cardiovascular Events with

Secukinumab: A Pooled Analysis of Data from Phase 2 and 3

Clinical Trials in Psoriasis”, Federation of Clinical Immunology

Societies, Chicago, IL

Organizing Roles in Scientific Meetings:

2008 American College of Physicians Pennsylvania State Chapter

Executive Committee

Harrisburg, PA

Nov, 2009 American Heart Association Council of Epidemiology and

Prevention, Early Career Symposium Booth

Orlando FL

2009 American Heart Association, Council on Epidemiology and

Prevention 39th Annual Meeting, Early Career Annual Meeting

Planning Committee

Marlton, FL

Nov, 2010 Moderator, Early Career Committee Workshop, American Heart

Association Scientific Sessions

Chicago, IL


Mar, 2011 Moderator, Obesity and Cardiovascular Disease, American College

of Cardiology Sessions

New Orleans, LA

Nov, 2011 Moderator, Functional Genomics and Translational Biology (FGTB)

of the American Heart Association Early Career Session

Orlando, FL

2012 Organizing Member, American Heart Association

NPAM/Epidemiology Annual Meeting Sessions 2012

TBD

Nov, 2012 Moderator, Early Career Session, American Heart Association

Mar, 2013 Moderator, Traditional or New Risk Factors, NPAM/Epidemiology

Annual Scientific Sessions, New Orleans, LA

Mar, 2013 Moderator, “Acute Coronary Syndromes: Basic II”, American

College of Cardiology 62nd

Annual Scientific Sessions, San

Francisco, CA

Bibliography:

Research Publications, peer reviewed (print or other media):

1. Windsor J, Santoian EC, Tarazona N, Mehta NN, Malosky SA and Dennis CA: Local

and Systemic Steroids in a Swine Model of Arterial Injury. Journal of

Investigative Medicine 43(2): 271-3, Apr 1995.

2. Ferrari VA, Mehta NN, Soulen M, Roberts DA, St John SM: Images in cardiovascular

medicine. Pulmonary venous aneurysms in hereditary hemorrhagic telangiectasia

detected by 3-dimensional magnetic resonance angiography. Circulation 108(17):

e122-3, Oct 2003. PMCID: PMC1470768

3. Mehta NN, Loria PM, Hobert O: A genetic screen for neurite outgrowth mutants in

Caenorhabditis elegans reveals a new function for the F-box ubiquitin ligase

component LIN-23. Genetics 166(3): 1253-67, Mar 2004. PMCID: PMC1470768

4. Mehta, NN. Romanelli, J. Sutton, M, Graham St J.: Native aortic valve vegetative

endocarditis with Cunninghamella. European Journal of Echocardiography 5(2):

156-8, Mar 2004. PMCID: PMC1470768

5. Reilly MP, Wolfe ML, Rhodes T, Girman C, Mehta NN, Rader DJ: Measures of

insulin resistance add incremental value to the clinical diagnosis of metabolic

syndrome in association with coronary atherosclerosis. Circulation 110(7): 803-9,

Aug 2004. PMCID: PMC2218847

6. Mehta NN and Reilly MP. : Assessment of Cardiovascular Risk in the HAART-

Treated HIV-1 Population. HIV Clinical Trials 6(1): 5-24, Jan/Feb 2005.

7. Chokshi, R. Openshaw, J. Mehta, NN. Mohler, E 3rd.: Purple glove syndrome

following intravenous phenytoin administration. Vascular Medicine 12(1): 29-31,

Feb 2007. PMCID: PMC2218847


8. Anderson PD, Mehta NN, Wolfe ML, Hinkle ChC, Pruscino L, Comiskey LL, Tabita-

Martinez J, Sellers KF, Rickels MR, Ahima RS, Reilly MP: Innate immunity

modulates adipokines in humans. The Journal of clinical endocrinology and

metabolism 92(6): 2272-9, Jun 2007. PMCID: PMC2218847

9. Nolan A, Weiden M, Kelly A, Hoshino Y, Hoshino S, Mehta NN, Gold JA: CD40 and

CD80/86 act synergistically to regulate inflammation and mortality in

polymicrobial sepsis. American journal of respiratory and critical care medicine

177(3): 301-8, Feb 2008. PMCID: PMC2218847

10. Qasim A, Mehta NN, Tadesse MG, Wolfe ML, Rhodes T, Girman C, Reilly MP:

Adipokines, insulin resistance, and coronary artery calcification. Journal of the

American College of Cardiology 52(3): 231-6, Jul 2008. PMCID: PMC2712798

11. Mehta NN, Sheetz M, Price K, Comiskey L, Amrutia S, Iqbal N, Mohler ER,

Reilly MP: Selective PKC Beta Inhibition with Ruboxistaurin and Endothelial

Function in Type-2 Diabetes Mellitus. Cardiovasc Drugs Ther 23(1): 17-24, Feb

2009. PMCID: 18949545

12. Mehta NN, Sheetz M, Price K, Comiskey L, Amrutia S, Iqbal N, Mohler ER, Reilly

MP: Selective PKC beta inhibition with ruboxistaurin and endothelial function in

type-2 diabetes mellitus. Cardiovascular drugs and therapy / sponsored by the

International Society of Cardiovascular Pharmacotherapy 23(1): 17-24, Feb 2009.

PMCID: PMC3088108

13. Martin SS, Qasim AN, Mehta NN, Wolfe M, Terembula K, Schwartz S, Iqbal N,

Schutta M, Bagheri R, Reilly MP: Apolipoprotein B but not LDL cholesterol is

associated with coronary artery calcification in type 2 diabetic whites. Diabetes

58(8): 1887-92, Aug 2009. PMCID: PMC2712798

14. Shah R, Lu Y, Hinkle CC, McGillicuddy FC, Kim R, Hannenhalli S, Cappola TP,

Heffron S, Wang X, Mehta NN, Putt Mary, Reilly Muredach P: Gene profiling of

human adipose tissue during evoked inflammation in vivo. Diabetes 58(10):

2211-9, Oct 2009. PMCID: PMC2750231

15. Mehta NN, McGillicuddy FC, Anderson PD, Hinkle CC, Shah R, Pruscino L, Tabita-

Martinez J, Sellers KF, Rickels MR, Reilly MP: Experimental endotoxemia

induces adipose inflammation and insulin resistance in humans. Diabetes 59(1):

172-81, Jan 2010. PMCID: PMC2797919

16. Mehta NN, McGillicuddy F, Anderson P, Hinkle C, Shah R, Pruscino L, Tabita-

Martinez J, Sellers K, Rickels MR, Reilly MP : Experimental Endotoxemia

Induces Adipose Inflammation and Insulin Resistance in Humans. Diabetes 59(1):

S1-8, Jan 2010 Notes: Supplemental data. PMCID: 19794059


17. Eraso LH, Ginwala N, Qasim AN, Mehta NN, Dlugash R, Kapoor S, Schwartz S,

Schutta M, Iqbal N, Mohler ER, Reilly MP: Association of lower plasma fetuin-a

levels with peripheral arterial disease in type 2 diabetes. Diabetes care 33(2): 408-

10, Feb 2010. PMCID: PMC2809293

18. Qasim AN, Martin SS, Mehta NN, Wolfe ML, Park J, Schwartz S, Schutta M, Iqbal

Nayyar, Reilly MP: Lipoprotein(a) is strongly associated with coronary artery

calcification in type-2 diabetic women. International journal of cardiology 150(1):

17-21, Mar 2010. PMCID: PMC2988112

19. Gelfand JM, Azfar RS, Mehta NN: Psoriasis and cardiovascular risk: strength

innumbers. Journal of Investigative Dermatology 130(4): 919-922, April 2010.

20. Mehta NN, Azfar RS, Shin DB, Neimann AL, Troxel AB, Gelfand JM: Patients with

severe psoriasis are at increased risk of cardiovascular mortality: cohort study

using the General Practice Research Database. European heart journal 31(8):

1000-6, Apr 2010. PMCID: PMC2894736

21. Bagheri R, Qasim AN, Mehta NN, Terembula K, Kapoor S, Braunstein S, Schutta M,

Iqbal N, Lehrke M, Reilly MP: Relation of plasma fatty acid binding proteins 4

and 5 with the metabolic syndrome, inflammation and coronary calcium in

patients with type-2 diabetes mellitus. The American journal of cardiology

106(8): 1118-23, Oct 2010. PMCID: PMC3086062

22. Shen H, Bielak LF, Ferguson JF, Streeten EA, Yerges-Armstrong LM, Liu J, Post W,

O'Connell JR, Hixson JE, Kardia SL R, Sun YV, Jhun MA, Wang X, Mehta NN,

Li M, Koller DL, Hakonarson H, Keating BJ, Rader DJ, Shuldiner AR, Peyser

PA, Reilly MP, Mitchell BD: Association of the vitamin D metabolism gene

CYP24A1 with coronary artery calcification. Arteriosclerosis, thrombosis, and

vascular biology 30(12): 2648-54, Dec 2010. PMCID: PMC2988112

23. Qasim AN, Budharaju V, Mehta NN, St Clair C, Farouk S, Braunstein S, Schutta M,

Iqbal N, Rader DJ, Reilly MP: Gender differences in the association of C-reactive

protein with coronary artery calcium in type-2 diabetes. Clinical endocrinology

74(1): 44-50, Jan 2011. PMCID: PMC3005137

24. Reilly MP, Li M, He J, Ferguson JF, Stylianou IM, Mehta NN, Burnett MS, Devaney

JM, Knouff CW, Thompson JR, Horne BD, Stewart AFR, Assimes TL, Wild PS,

Allayee H, Nitschke PL, Patel RS, Martinelli N, Girelli D, Quyyumi AA,

Anderson JL, Erdmann J, Hall AS, Schunkert H, Quertermous T, Blankenberg S,

Hazen SL, Roberts R, Kathiresan S, Samani NJ, Epstein SE, Rader DJ:

Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and

association of ABO with myocardial infarction in the presence of coronary

atherosclerosis: two genome-wide association studies. Lancet 377(9763): 383-92,

Jan 2011. PMCID: PMC3086062


25. Wade AN, Fedyna S, Mehta NN, St Clair C, Ginwala N, Krishna RK, Qasim AN,

Braunstein S, Iqbal N, Schutta MH, Reilly MP: Type 2 diabetes does not attenuate

racial differences in coronary calcification. Diabetes research and clinical practice

91(1): 101-7, Jan 2011. PMCID: PMC3086062

26. Martin SS, Qasim AN, Wolfe M, St Clair C, Schwartz S, Iqbal N, Schutta M, Bagheri

R, Mehta NN, Rader DJ, Reilly MP: Comparison of high-density lipoprotein

cholesterol to apolipoprotein A-I and A-II to predict coronary calcium and the

effect of insulin resistance. The American journal of cardiology 107(3): 393-8,


27. Mehta NN, Krishnamoorthy P, Martin SS, St Clair C, Schwartz S, Iqbal N,

Braunstein S, Schutta M, Rader DJ, Reilly MP: Usefulness of insulin resistance

estimation and the metabolic syndrome in predicting coronary atherosclerosis in

type 2 diabetes mellitus. The American journal of cardiology 107(3): 406-11, Feb

2011. PMCID: PMC3040419

28. Mehta NN, Li M, William D, Khera AV, Derohannessian S, Qu L, Ferguson JF,

McLaughlin C, Shaikh LH, Shah R, Patel PN, Bradfield JP, He J, Stylianou IM,

Hakonarson H, Rader DJ, Reilly MP: The novel atherosclerosis locus at 10q11

regulates plasma CXCL12 levels. European heart journal 32(8): 963-71, Apr

2011. PMCID: PMC3076669

29. Beheshti M, Saboury B, Mehta NN, Torigian DA, Werner T, Mohler E, Wilensky R,

Newberg AB, Basu S, Langsteger W, Alavi A: Detection and global

quantification of cardiovascular molecular calcification by fluoro18-fluoride

positron emission tomography/computed tomography--a novel concept. Hellenic

journal of nuclear medicine 14(2): 114-20, May-Aug 2011. PMCID:

PMC3146037

30. Mehta NN, Yu Y, Saboury B, Foroughi N, Krishnamoorthy P, Raper A, Baer A,

Antigua J, Van Voorhees AS, Torigian DA, Alavi A, Gelfand JM: Systemic and

Vascular Inflammation in Patients With Moderate to Severe Psoriasis as

Measured by [18F]-Fluorodeoxyglucose Positron Emission Tomography-

Computed Tomography (FDG-PET/CT): A Pilot Study. Archives of dermatology.

147(9): 1031-9, 2011 Sept. Notes: e pub ahead of print May 2011. PMCID:

PMC3158301

31. Shah R, Hinkle CC, Ferguson JF, Mehta NN, Li M, Qu L, Lu Y, Putt ME, Ahima RS,

Reilly MP: Fractalkine is a novel human adipochemokine associated with type 2

diabetes. Diabetes 60(5): 1512-8, May 2011. PMCID: PMC3292325


32. Wild PS, Zeller T, Schillert A, Szymczak S, Sinning CR, Deiseroth A, Schnabel RB,

Lubos E, Keller T, Eleftheriadis MS, Bickel C, Rupprecht HJ, Wilde S, Rossmann

H, Diemert P, Cupples AL, Perret C, Erdmann J, Stark K, Kleber ME, Epstein SE,

Voight BF, Kuulaasma K, Li M, Schäfer AS, Klopp N, Braund PS, Sager HB,

Demissie S, Proust C, König IR, Wichmann H-E, Reinhard W, Hoffmann MM,

Virtamo J, Burnett MS, Siscovick D, Wiklund PG, Qu LL, El Mokthari NE,

Thompson JR, Peters A, Smith AV, Yon E, Baumert J, Hengstenberg C, März W,

Amouyel P, Devaney J, Schwartz SM, Saarela O, Mehta NN, Rubin D, Silander

K, Hall AS, Ferrieres J, Harris TB, Melander O, Kee F, Hakonarson H,

Schrezenmeir J, Gudnason V, Elosua R, Arveiler D, Evans A, Rader DJ, Illig T,

Schreiber S, Bis JC, Altshuler D, Kavousi M, Witteman JCM, Uitterlinden AG,

Hofman A, Folsom AR, Barbalic M, Boerwinkle E, Kathiresan S, Reilly MP,

O'Donnell CJ, Samani NJ, Schunkert H, Cambien F, Lackner KJ, Tiret L,

Salomaa V, Munzel T, Ziegler A, Blankenberg S: A Genome-wide Association

Study Identifies LIPA as a Susceptibility Gene for Coronary Artery Disease.

Circulation. Cardiovascular genetics 4(4): 403-12, May 2011. PMCID:

PMC3157552

33. Hasan R, GN, Shah R, KD, Wilensky R, Mehta NN: Quantitative Angiography of

Coronary Artery Disease in South Asians Reveals Differences in Vessel Size and

Disease Severity Compared to Caucasians. American Journal of Cardiovascular

Diseases 1(1), Jun 2011 Notes: in press.

34. Mehta NN & Rader DJ: Imaging with Indocyanine Green: Light at the End of the

Catheter? Cell Metabolism Jul 2011 Notes: in press, accepted June 18th, 2011.

35. Beheshti M, Saboury B, Mehta NN, Torigian DT, Werner T, Mohler ER, Wilensky R,

Newberg A, Basu S, Langsteger W, Alavi A: Detection and Global Quantification

of Cardiovascular Molecular Calcification by 18F-Fluoride PET/CT: A Novel

Concept Hellenic Journal of Nuclear Medicine Aug 2011 Notes: in press,

accepted June 15, 2011.

36. Mehta NN, Yu Y, Pinnelas R, Krishnamoorthy P, Shin DB, Troxel AB, Gelfand JM:

Attributable risk estimate of severe psoriasis on major cardiovascular events. The

American journal of medicine 124(8): 775.e1-6, Aug 2011. PMCID:

PMC3146037

37. Mehta NN, Yu Y, Pinnelas R, Krishnamoory PK, Shin DB, Troxel AB, Gelfand JM:

Attributable Risk Estimate of Psoriasis on Major Adverse Cardiovascular Events.

American Journal of Medicine Aug 2011 Notes: in press August 2011, accepted

May 20, 2011.


38. Kimball AB, Szapary P, Mrowietz U, Reich K, Langley RG, You Y, Hsu Yielding

NM, Rade DJ, Mehta NN: Underdiagnosis and undertreatment of cardiovascular

risk factors in patients with moderate-to-severe psoriasis. Journal of the American

Academy of Dermatology 67(1):76-85, Jul 2012. Notes: Epub ahead of print Oct

2011.

39. Kimball AB, Szapary P, Mrowietz U, Reich K, Langley RG, You Y, Hsu M-C,

Yeilding N, Rader DJ, Mehta NN: Underdiagnosis and undertreatment of

cardiovascular risk factors in patients with moderate to severe psoriasis. Journal

of the American Academy of Dermatology 67(1): 76-85, Oct 2011. PMCID:

PMC3278499

40. Hasan RK, Ginwala NT, Shah RY, Kumbhani DJ, Wilensky RL, Mehta NN:

Quantitative angiography in South Asians reveals differences in vessel size and

coronary artery disease severity compared to Caucasians. American journal of

cardiovascular disease 1(1): 31-7, 2011. PMCID: PMC3253512

41. Langan SM, Seminara, NM, Shin, DB, Troxel A, Kimmel SE, Mehta NN, Margolis

DJ, and Gelfand JM. : Prevalence of metabolic syndrome in patients with

psoriasis: A population-based study in the United Kingdom. Journal of

Investigative Dermatology 132(3 Pt 1):556-62, Mar 2012. Notes: Epub ahead of

print Nov 2011.

42. Ferguson JF, Hinkle CC, Mehta NN, Bagheri R, Derohannessian SL, Shah R,

Mucksavage MI, Bradfield JP, Hakonarson H, Wang X, Master SR, Rader DJ, Li

M, Reilly MP: Translational studies of lipoprotein-associated phospholipase

Aâ‚in inflammation and atherosclerosis. Journal of the American College of

Cardiology 59(8): 764-72, Feb 2012. PMCID: PMC3285416

43. de la Llera MM, McGillicuddy FC, Hinkle CC, Byrne M, Joshi MR, Nguyen V,

Tabita-Martinez J, Wolfe ML, Badellino K, Pruscino L, Mehta NN, Asztalos BF,

Reilly MP: Inflammation modulates human HDL composition and function in

vivo. Atherosclerosis 222(2): 390-4, Jun 2012. Notes: Epub ahead of print Feb

2012. PMCID: PMC3361641

44. Langan SM, Seminara NM, Shin DB, Troxel AB, Kimmel SE, Mehta NN, Margolis

DJ, Gelfand JM: Prevalence of metabolic syndrome in patients with psoriasis: a

population-based study in the United Kingdom. The Journal of investigative

dermatology 132(3 Pt 1): 556-62, Mar 2012. PMCID: PMC3278499

45. Mehta NN, Torigian DA, Gelfand JM, Saboury B, Alavi A: Quantification of

Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F]

Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography

(FDG-PET/CT). Journal of visualized experiments (63):e3777, May 2012.


46. Mehta NN, Heffron SP, Patel PN, Ferguson J, Shah RD, Hinkle CC, Krishnamoorthy

P, Shah R, Tabita-Martinez J, Terembula K, Master SR, Rickels MR, Reilly MP:

A human model of inflammatory cardio-metabolic dysfunction; a double blind

placebo-controlled crossover trial. Journal of Translational Medicine 10(1): 124,

Jun 2012.

47. Mehta NN, Krishnamoorthy P, Yu Y, Khan O, Raper A, Van Voorhees A, Troxel

AB, Gelfand JM: The impact of psoriasis on 10-year Framingham risk. Journal of

the American Academy of Dermatology 67(4):796-8, Oct 2012. Notes: Epub

ahead of print Jun 2012.

48. Baker JF, Mehta NN, Baker DG, Toedter G, Shults J, Von Feldt JM, Leonard MB:

Vitamin D, Metabolic Dyslipidemia, and Metabolic Syndrome in Rheumatoid

Arthritis. The American Journal of Medicine 125(10):1036.e9-1036.e15, Oct

2012. Notes: Epub ahead of print Jul 2012.

49. Gaieski DF, Goldman JD, Holtzman DL, Shoff WH, Shepherd SM, Mehta NN, Goyal

M: Algid malaria treated with early goal-directed therapy. The American Journal

of Emergency Medicine 31(1):263.e5-263.e10, Jan 2013. Notes: Epub ahead of

print Jul 2012.

50. Mehta NN, Li R, Krishnamoorthy P, Yu Y, Farver W, Rodrigues A, Raper A, Wilcox

M, Baer A, Derohannesian S, Wolfe M, Reilly MP, Rader DJ, Vanvoorhees A,

Gelfand JM: Abnormal lipoprotein particles and cholesterol efflux capacity in

patients with psoriasis. Atherosclerosis 224(1):218-21, Sept 2012. Notes: Epub

ahead of print Jul 2012.

51. Shah R, Hinkle CC, Haris L, Shah R, Mehta NN, Putt ME, Reilly MP: Adipose

Genes Down-Regulated During Experimental Endotoxemia Are Also Suppressed

in Obesity. The Journal of clinical endocrinology and metabolism 97(11):E2152-

9, Nov 2012. Notes: Epub ahead of print Aug 2012.

52. Mulvey CK., Ferguson JF., Tabita-Martinez J, Kong S, Shah RY., Patel PN., Master

SR., Usman MHU., Propert KJ., Shah R, Mehta NN., Reilly MP.: Peroxisome

Proliferator–Activated Receptor-α Agonism With Fenofibrate Does Not Suppress

Inflammatory Responses to Evoked Endotoxemia. J Am Heart Assoc

1(4):e002923, Aug 2012.


53. Mehta NN. Journal of Translational Medicine introduces a new section of

Cardiovascular, Metabolic and Lipoprotein Translation. J of Translational

Medicine 10(1):203, Sept 2012. Epub Ahead.

54. Yu Y, Sheth N, Krishnamoorthy P, Saboury B, Raper A, Baer A, Ochotony R,

Doveikis J, Derohannessian S, Voorhees AS, Torigian DA, Alavi A, Gelfand JM,

Mehta NN. Aortic vascular inflammation in psoriasis is associated with HDL

particle size and concentration: a pilot study. Am J Cardiovasc Dis 2(4):285-92,

Oct 2012.

55. Ogdie A, Langan S, Love T, Haynes K, Shin D, Seminara N, Mehta NN, Troxel A,

Choi H, Gelfand JM. Prevalence and treatment patterns of psoriatic arthritis in

the United Kingdom. Rheumatology (Oxford) Dec 2012. Epub Ahead.

56. Mehta NN. Large-scale association analysis provides insights into the genetic

architecture and pathophysiology of type 2 diabetes mellitus. Circ Cardiovasc

Genet 5(6):708-10, Dec 2012.

57. Bose S, Krishnamoorthy P, Varanasi A, Nair J, Schutta M, Braunstein S, Iqbal N,

Schwartz S, Clair CS, Master SR, Rader DJ, Reilly MP, Mehta NN.

Measurement of waist circumference predicts coronary atherosclerosis beyond

plasma adipokines. Obesity 21(1):E118-23, Jan 2013.


58. Ferguson JF, Patel PN, Shah RY, Mulvey CK, Gadi R, Nijjar PS, Usman HM, Mehta

NN, Shah R, Master SR, Propert KJ, Reilly MP. Race and gender variation in

response to evoked inflammation. J Transl Med 11(1):63, Mar 2013. Epub ahead.

59. Ferguson JF, Matthews GJ, Townsend RR, Raj DS, Kanetsky PA, Budoff M, Fischer

MJ, Rosas SE, Kanthety R, Rahman M, Master SR, Qasim A, Li M, Mehta NN,

Shen H, Mitchell BD, O’Connell JR, Shuldiner AR, Ho WK, Young R, Rasheed

A, Danesh J, He J, Kusek JW, Ojo AO, Flack J, Go AS, Gadegbeku CA, Wright

JT, Saleheen D, Feldman HI, Rader DJ, Foulkes AS, Reilly MP. Candidate Gene

Association Study of Coronary Artery Calcification in Chronic Kidney Disease:

Findings from the Chronic Renal Insufficiency Cohort Study. J Am Coll Cardiol.

S0735-1097(13)02075-5, May 2013.

60. Blomberg BA, Akers SR, Saboury B, Mehta NN, Cheng G, Torigian DA, Lim E, Del

Bello C, Werner TJ, Alavi A. Delayed time-point 18F-FDG PET CT imaging

enhances assessment of atherosclerotic plaque inflammation. Nucl Med Commun.

June 24, 2013 [Epub ahead of print].

61. Mulvey CK, McNeill AM, Girman CJ, Churchill TW, Terembula K, Ferguson JF,

Shah R, Mehta NN, Qasim AN, Rickels MR, Reilly MP. Differential Associations

of Oral Glucose Tolerance Test-Derived Measures of Insulin Sensitivity and

Pancreatic Beta-Cell Function with Coronary Artery Calcification and

Microalbuminuria in Type 2 Diabetes. Diabetes Care. 2013 Aug 15. [Epub ahead

of print]

62. Mehta NN, Li K, Szapary P, Krueger J, Brodmerkel C. Modulation of

cardiometabolic pathways in skin and serum from patients with psoriasis. J Transl

Med. 2013 Aug 22;11(1):194. [Epub ahead of print]

63. Rose S, Sheth N, Baker J, Ogdie A, Raper A, Saboury B, Werner TJ, Thomas P,

Vanvoorhees A, Alavi A, Torigian D, Gelfand J, Mehta NN. A comparison of

vascular inflammation in psoriasis, rheumatoid arthritis, and healthy subjects by

FDG-PET/CT: a pilot study. Am J Cardiovasc. 2013 [Epub ahead of print]

64.Yueng H, Takeshita J, Mehta NN, Kimmel SE, Ogdie A, Margolis DJ, Shin DB, Attor

R, Troxel AB, Gelfand JM. Psoriasis severity and the prevalence of major

medical comorbity: a population-based study. JAMA Dermatol. 2013.

65. Ferguson JF, Mulvey CK, Patel PN, Shah RY, Doveikis J, Zhang W, Tabita-Martinez

J, Terembula K, Eiden M, Koulman A, Griffin JL, Mehta NN, Shah R, Propert

KJ, Song WL, Reilly MP. Mol Nutr Food Res. 2013 Nov 5.

66. Mehta NN, Matthews GJ, Krishnamoorthy P, Shah R, McLaughlin C, Patel P, Budoff

M, Chen J, Wolman M, Go A, He J, Kanetsky PA, Master SR, Rader DJ, Raj D,

Gadegbeku CA, Shah R, Shreiber M, Fischer MJ, Townsend RR, Kusek J,

http://www.ncbi.nlm.nih.gov/pubmed/23949560







Feldman HI, Foulkes AS, Reilly MP; the Chronic Renal Insufficiency Cohort

(CRIC) Study Investigators. Higher plasma CXCL12 levels predict incident

myocardial infarction and death in chronic kidney disease: findings from the

Chronic Renal Insufficiency Cohort study. Eur Heart J. 2013 Dec 4.

67. Li RC, Krishnamoorthy P, DerOhannessian S, Doveikis J, Wilcox M, Thomas P,

Rader DJ, Reilly MP, Van Voorhees A, Gelfand JM, Mehta NN. Psoriasis is

associated with decreased plasma adiponectin levels independently of

cardiometabolic risk factors. Clin. Exp. Dematol. 2014 vol. 39(1) pp. 19-24.

68. Dave J, Ahlman M, Lockshin B, Mehta NN. Vascular inflammation in psoriasis

localizes to the arterial wall using a novel imaging technique. JAAD. E-pub

ahead.

69. Roe A, Hillman J, Butts S, Smith M, Rader D, Playford M, Mehta NN, Dokras A.

Decreased cholesterol efflux capacity and atherogenic lipid profile in young

women with PCOS. J. Clin. Endocrinol. Metab., 2014.

70. Mehta NN, Gelfand JM. High-density lipoprotein cholesterol function improves after

successful treatment of psoriasis: a step forward in the right direction. J. Invest.

Dermatol., 2014. Vol. 134(3) pp. 592-5.

71. Ferguson JF, Mulvey CK, Patel PN, Shah RY, Doveikis J, Zhang W, Tabita-Martinez

J, Terembula K, Eiden M, Koulman A, Griffin JL, Mehta NN, Shah R, Propert

KJ, Song WL, Reilly MP. Omega-3 PUFA supplementation and the response to

evoked endotoxemia in healthy volunteers. Mol. Nutr. Food. Res. 2014. Mar,

58(3) 601-3.

72. Dominic EA, Ramezani A, Anker SD, Verma M, Mehta N, Rao M. Mitochondrial

cytopathies and cardiovascular disease. Heart. 2014 Jan 21.

73. Takeshita J, Mohler ER, Krishnamoorthy P, Moore J, Rogers WT, Zhang L, Gelfand

JM, Mehta NN. Endothelial cell-, platelet-, and monocyte/macrophage-derived

microparticles are elevated in psoriasis beyond cardiometabolic risk factors. J Am

Heart Assoc. 2014 Feb 28; 3(1).

74. Mehta N, Qamar A, Qu L, Qasim AN, Mehta NN, Reilly MP, Rader DJ. Differential

association of plasma angiopoitin-like proteins 3 and 4 with lipid and metabolic

traits. Arterioscler Thromb Vasc Biol. 2014 May; 34(5).

75. Mehta NN, Dagur PK, Rose SM, Naik HB, Stansky E, Doveikis J, Biancotto A,

Playford MP, McCoy JP Jr. IL-17A production in human psoriatic blood and


lesions by CD146+ T cells. J Invest Dermatol. 2014 July 24.

76. Subramanain S, Liu C, Aviv A, Ho JE, Courchesne P, Muntendam P, Larson MG,

Cheng S, Wang TJ, Mehta NN, Levy D. Stromal cell-derived factor 1 as a

biomarker of heart failure and mortality risk. Arterioscler Thromb Vasc Biol.

2014 Jul 24.

77. Rose S, Dave’ J, Millo C, Naik HB, Siegel EL, Mehta NN. Psoriatic arthritis and

sacroiliitis are associated with increased vascular inflammation by

18fluorodeoxyglucose positron emission tomography computed tomography:

baseline report from the Psoriasis Atherosclerosis and Cardiometabolic Disease

Initiative. Arthritis Res Ther. 2014 Jul 30; 16(4):R161 [Epub ahead of print].

Research Publications, peer-reviewed reviews:

1. Mehta NN, Reilly M: Atherosclerotic cardiovascular disease risk in the HAART-

treated HIV-1 population. HIV clinical trials 6(1): 5-24, Jan-Feb 2005. PMCID:

PMC2218847

2. Mehta NN, and Reilly MP.: Mechanisms and Components of the Metabolic

Syndromes. Drug Discovery Today: Disease Mechanisms. 1(1): 1-16, Mar 2005.

3. Shah A, Mehta NN, Reilly MP: Adipose inflammation, insulin resistance, and

cardiovascular disease. JPEN. Journal of parenteral and enteral nutrition 32(6):

638-44, Nov-Dec 2008. PMCID: PMC2712798

4. Gelfand JM, Azfar RS, Mehta NN: Psoriasis and cardiovascular risk: strength in

numbers. The Journal of investigative dermatology 130(4): 919-22, Apr 2010.

PMCID: PMC2866113

5. Farouk SS, Rader DJ, Reilly MP, Mehta NN: CXCL12: a new player in coronary

disease identified through human genetics. Trends in cardiovascular medicine

20(6): 204-9, Aug 2010. PMCID: PMC3235407

6. Gelfand JM, Mehta NN, Langan SM: Psoriasis and Cardiovascular Risk: Strength in

Numbers, Part II. The Journal of investigative dermatology 131(5): 1007-10, May

2011. PMCID: PMC3292325

7. Mehta NN: Large-scale association analysis identifies 13 new susceptibility Loci for

coronary artery disease. Circulation. Cardiovascular genetics 4(3): 327-9, Jun

2011. PMCID: PMC3125595

8. Mehta NN, Rader DJ: Fluorescent green plaques: light at the end of the catheter? Cell

metabolism 14(1): 7-8, Jul 2011. PMCID: PMC3138117


9. Mehta NN: A genome-wide association study in europeans and South asians identifies

5 new Loci for coronary artery disease. Circulation. Cardiovascular genetics 4(4):

465-6, Aug 2011. PMCID: PMC3190399

10. Mehta NN: Large-scale gene-centric analysis identifies novel variants for coronary

artery disease. PLoS genetics 7(9): e1002260, Sep 2011. PMCID: PMC3178591

11. Mehta, NN.: A GWAS of South Asians and Europeans Detects Five Novel CAD

Loci. Circulation. Cardiovascular Genetics in press: accepted 7/6/11, September

2011.

12. Farouk S, Rader DJ, Reilly MP, Mehta NN: CXCL12: A New Player in Coronary

Disease Identified through Human Genetics Trends in Cardiovascular Medicine

2011 Notes: in press.

13. Mehta NN: The effect of chromosome 9p21 variants on cardiovascular disease may

be modified by dietary intake. Circulation. Cardiovascular genetics 5(1): 148-50,

2012 Feb 1. PMCID: PMC3285416

14. Mehta NN, Reilly Muredach P: Monocyte mayhem: do subtypes modulate distinct

atherosclerosis phenotypes? Circulation. Cardiovascular genetics 5(1): 7-9, 2012


Research Publications, non-peer reviewed:

1. Mehta, NN.: Novel Risk Factors and Primary Prevention of Coronary Artery Disease.

Hospital Physician Page: 1-9, Aug 2006.

Abstracts:

1. Mehta, NN, Schutta, M, Wolfe, ML, Iqbal, N, Kimmel, SE, Rader, DJ, Reilly, MP:

Plasma adiponectin levels, cardiovascular risk factors, and coronary

atherosclerosis in type 2 diabetes. Arteriosclerosis Thrombosis And Vascular

Biology 24(5): P243, May 2004.

2. Reilly MP, Wolfe M, Rhodes T, Girman C, Mehta NN, Rader DJ.: Measures of Insulin

Resistance Add Incremental Value to the NCEP Metabolic Syndrome Criteria in

the Association with Coronary Artery Calcification. Circulation 110(7), Aug

2004.

3. Anderson, PD, Mehta, NN, Wolfe, ML, McMahon, K, Hinkle, C, Comiskey, L,

Tabita-Martinez, J, Sellers, K, Ahima, BS, Rader, DJ, Reilly, MP: Adipokines

in human endotoxemia. Journal Of Investigative Medicine 53(2): S388, Mar

2005.


4. Mehta, NN, Anderson, PD, Wolfe, M, Rickels, M, Zemel, B, Hinkle, C, Comiskey,

L, Tabita-Martinez, J, Ahima, R, Rader, DJ, Reilly, MP: Adiposity and pro-

atherosclerotic responses to innate immune challenge in humans. Journal Of

Investigative Medicine 53(2): S391, Mar 2005.

5. Anderson, P, Mehta, NN, Wolfe, ML, Hinkle, CC, Tabita-Martinez, JJ, Sellers, KF,

Rader, DJ, Reilly, MP: Atherogenic changes in apo-B lipoproteins during human

inflammation. Circulation 112(17 Suppl. S): 1215 Oct 2005.

6. Anderson, PD, Mehta, NN, Wolfe, ML, McMahon, KE, Hinkle, CC, Comiskey, L,

Tabita-Martinez, JJ, Sellers, KF, Ahima, RS, Rader, DJ, Reilly, MP:

Pathophysiology of insulin resistance in human inflammation. Circulation 112(17

Suppl. S): 3821, Oct 2005.

7. Anderson, P.A., Mehta, N., wolfe, M.L., McMahon, K., Hinkle, C., Comiskey, L.,

Tanbita-Marinez, J., Sellers, K., Ahima, R. S., Rader, D.J., Reilly, M.P.:

Pathophysiology of insulin resistance in human inflammations. Circulation

112(II): 827, 2005.

8. Mehta, NN, Anderson, P, Wolfe, M, Rickels, M, Zemel, B, Hinkle, C, Tabita-

Martinez, J, Ahima, R, Sellers, K, Rader, DJ, Reilly, MP: Adiposity and

atherogenic inflammatory response to endotoxin in humans. Journal Of The

American College Of Cardiology 47(4 Suppl. A): 308A, Feb 2006.

9. Mehta, NN, Anderson, PD, Hinkle, C, Tabita-Martinez, J, Rickels, MR, Reilly, MP:

Modulation of the insulin signaling pathway in human inflammation.

Arteriosclerosis Thrombosis And Vascular Biology 26(5): E49, May 2006.

10. Mehta, Nehal N, Mohler, Emile R, III, Amrutia, Shirsh, Reilly, Muredach P:

Abstract 3923: The Effect of Selective PKC-Inhibitor Ruboxistaurin on

Endothelial Function and Oxidant Stress in Patients with Type 2 Diabetes

Mellitus. Circulation 114: II_843-c- 2006.

11. de la Llera-Moya, Margarita, Pruscino, Leticia, Wolfe, Megan L, Nguyen, Vihn,

Mehta, Nehal, Reilly, Muredach P: Abstract 670: Serum Amyloid A May

Attenuate the Loss of HDL Efflux Capacity During Human Endotoxemia.

Circulation 114: II_112-b- 2006.

12. Heffron, SP, Mehta, NN, de la Llera-Moya, M, Pruscino, L, Tabita-Martinez, J,

Wolfe, M, Badelino, K, Rader, DJ, Reilly, MP: Degree of acute phase response

predicts extent of HDL remodeling in human inflammation. Arteriosclerosis

Thrombosis And Vascular Biology 27(6): E68, Jun 2007.


13. Heffron, SP, Mehta, NN, de la Llera-Moya, M, Terembula, K, Hinkle, C, Wolfe,

M, Reilly, MP: Abstract 1097: Very-low Dose Endotoxemia Induces High

Density Lipoprotein Remodeling and Reduces Cholesterol Efflux in the Absence

of a Clinical Inflammatory Response. Circulation 116: II_220-a- 2007.

14. Mehta, NN, Heffron, SP, Rickels, MR, Terembula, K, Ginwala, NT, Hinkle, C,

Wolfe, ML, Rader, DJ, Reilly, MP: Abstract 3593: Very-low Dose Endotoxemia

Induces Insulin Resistance in the Absence of Clinical Inflammatory Responses.

Circulation 116: II_814- 2007.

15. Varanasi, A, Mehta, NN, Hinkle, C, Udupa, J, Ginwala, NT, Reilly, MP:

Relationship between visceral adiposity, inflammatory markers, and insulin

resistance following human endotoxemia. Arteriosclerosis Thrombosis And

Vascular Biology 28(6): P507, Jun 2008.

16. Qasim, AN, Martin, SS, Mehta, NN, Rader, D, Reilly, MP: Abstract 3210: Lp(a) is

Strongly Associated with Coronary Artery Calcification in Type 2 Diabetic

Women. Circulation 118: S_1113-c- 2008.

17. Mehta NN, William D, Khera A, Edmondson , Qasim A, Restine S, Pruscino L,

Hinkle C, He J, Stylianou I, Li M, Rader DJ, Reilly MP: A Novel GWAS

Atherosclerosis Locus Regulates Plasma Levels of CXCL12. Gordon Conference

Journal June 2009.

18. Mehta NN, Li M, Epstein S, Keating B, Hakonarson H, Rader DJ, Reilly MP.: The

ITMAT/Broad/CARE (IBC) Candidate Gene Array Identifies Novel Type 2

Diabetes Gene Associations with Coronary Artery Disease: The GRAND-CAD

Consortium. American Society of Human Genetics Nov 2009 Notes: (presentation

American Society of Human Genetics, 2008).

19. Martin SS, Rader DJ, Mehta NN, Wolfe M, Terembula K, Schwartz S, Iqbal N,

Schutta M, Bagheri R, Reilly MP, Qasim AN: Abstract 1618: High-Density

Lipoprotein Cholesterol but Not Apolipoprotein A-I or -II is Associated With

Coronary Calcium in Type 2 Diabetes. Circulation 120(18_MeetingAbstracts):

S531- 2009.

20. Mehta, NN, Azfar, RS, Shin, DB, Neimann, AL, Troxel, AB, Gelfand, JM:

Abstract 1640: Patients With Severe Psoriasis and No History of Cardiovascular

Disease Are at Increased Risk of Cardiovascular Mortality. Circulation 120:

S536-b- 2009.

21. Mehta, NN, William, D, Pruscino, L, Khera, A, Edmondson, A, Qasim, A,

Restine, S, Hinkle, C, He, J, Stylianou, I, Li, M, Rader, DJ, Reilly, MP:

Abstract 2077: A Novel GWAS Atherosclerosis Locus Regulates Plasma Levels

of CXCL12. Circulation 120: S589-a- 2009.


22. Varanasi, A, Bose, S, Udupa, J, Duglash, R, Chandrupatla, H, Iqbal, N, Schutta,

M, Reilly, MP, Mehta, NN: Abstract 1623: Quantification of Visceral Adipose

Tissue Adds Value to BMI and Metabolic Syndrome in Prediction of Subclinical

Atherosclerosis in Men With Type 2 Diabetes. Circulation 120: S532- 2009.

23. Ferguson J, William D, Wang X, Qu L, Mehta NN, Reilly MP: Genetic variation in

CRP and PLA2G7 has differential associations with subclinical coronary

atherosclerosis. Arteriosclerosis, Thrombosis and Vascular Biology Annual

Conference 2010.

24. Eraso LH, Ferguson J, Mehta NN, Li M, Keating B, Mohler III ER, Reilly MP:

Candidate Gene Association Study of Peripheral Arterial Disease in Type 2

Diabetes. Arteriosclerosis, Thrombosis and Vascular Biology Annual Conference

2010.

25. Mehta, NN, Reilly, M, Rader, D, Mohler, E, VanVoorhees, A, Gelfand, J: Abstract

P040: Advanced cardiometabolic phenotyping in psoriasis links between psoriasis

and cardiovascular disease? 3rd

World Psoriasis & Psoriatic Arthritis Conference

2012.

26. Mehta NN, Matthews G, Budoff M, Chen J, Glenn M, Go A, He J, Kanetsky P,

Master S, Rader DJ, Raj D, Shah R, Screiber M, Fischer M, Townsend R, Kusek

J, Feldman H, Foulkes A, Reilly MP: Higher Plasma CXCL12 Levels Predict

Incident Cardiovascular Disease Events: Findings from the Chronic Renal

Insufficiency Cohort Study. American Heart Association Scientific Sessions

2012.

27. Sheth N, Baker J, Ogdie A, Roper A, Saboury B, Werner T, Thomas P, Van

Voorhees A, Alavi A, Torigian D, Gelfand J, Mehta NN: A Comparison of

Vascular Inflammation in Rheumatoid Arthritis, Psoriasis and Healthy Controls

by FDG-PET/CT: A pilot Study. American College of Cardiology Annual

Meeting 2013.

28. Mehta NN, Dagur PK, Stansky S, Rose S, Biancotto A, Sonti K, Playford M, McCoy

J.P.: CD146 expression identifies Th17 and Tc17 subsets in psoriatic blood and

skin. International Investigative Dermatology Conference 2013.

29. Rose S, Sonti K, Dagur P, Lee P, Playford M, Celi F, Mehta NN: Characterization of

adipose tissue inflammation may link psoriasis and cardiometabolic disease.

International Investigative Dermatology Conference 2013.

30. Sheth, NH, Baker J, Ogdie A, Roper A, Saboury B, Van Voorhees A, Alavi A,

Torigian D, Gelfand J, Mehta NN: The Use of FDG-PET/CT to Evaluate Vascular

Inflammation in Inflammatory Diseases Compared to Healthy Controls: A Pilot

Study. SNMMI Annual Meeting 2013.


31. Takeshita J, Saboury B, Salavati A, Torigian DA, Van Voorhees A, Mehta NN,

Alavi A, Gelfand JM: 18-Fluorodeoxyglucose Positron Emission Tomography-

Computed Tomography (FDG PET-CT) as a Novel Tool for Quantification of

Psoriasis Disease Activity: Proof of Concept from the Vascular Inflammation in

Psoriais (VIP) Trial. Journal of Investigative Dermatology. 133(1): S177, May

2013.

32. Krishnamoorthy P, Rader DJ, Reilly M, Mehta NN: Advanced Lipid Testing Predicts

Subclinical Atherosclerosis in Low Risk Population Beyond Traditional Risk

Factors. International Academy of Cardiology 2013.

33. Griffiths C, Reich K, Leonardi C, Blauvelt A, Mehta NN, Tsai T-F, Gong Y, Huang

J, Fox: Secukinumab Demonstrates an Acceptable Safety Profile in Moderate to

Severe Plaque Psoriasis: Pooled Analysis of 10 Phase 2/3 Studies. European

Academy of Dermatology and Venereology Congress 2014 Late Breaking

Abstract.

Books:

1. Christopher P. Cannon, MD and Nehal N. Mehta, MD, FACP: Contemporary

Guide to Cardiovascular Therapy. (First Edition), July 2008 Notes: ISBN

9781931981880.

2. Stephen Pan, MD, MS, Juyong Brian Kim, MD, MPH, Nehal N. Mehta, MD,

MSCE, FAHA, Joshua W. Knowles, MD, PhD, FAHA, FACC: “Genetic

Applications in Coronary Artery Disease,” in Cardiovascular Genetics and

Genomics in Clinical Practice. 2014.

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