New Clinical Profile of Children With Dengue Infection

8/3/2019 New Clinical Profile of Children With Dengue Infection

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PROF. HUMAYUN IQBAL KHANIMRAN YASIN

AAMIRRASHEED

SIKANDERIKRAM

CLINICAL PROFILE OF CHILDREN WITHDENGUE INFECTION


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INTRODUCTION

y Dengue is a mosquito borne viral illness caused by one of

the four serotypes DEN V.

y Mosquito that spread dengue virus belong to Aedesspecies; Aedes aegypti, Aedes albopictus.


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INTRODUCTION

y Disease is now endemic in more than 100 countries.

y WHO estimates that there may be 50 million dengue

infections every year.


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INTRODUCTION

y In our country Dengue has emerged as most important

arthropode borne illness over the past few years.

y It is possible for a person to be infected with dengue asmany as four times.


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INTRODUCTION

y As the dengue virus become endemic in a population, the

percentage of children among affected population

increases.

y So, a study was planned & conducted last year to see theclinical profile of children affected with dengue.


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Materials&Methods

y It was a descriptive study

.

y Department of Pediatrics

y From August 2011 to October 2011.


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Materials&Methods

y 254 admitted patients were included in study.

y Patients were divided in 3 groups;i. DF

ii. DHF

iii. Unusual dengue fever


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MATERIALS&METHODS

y The symptoms, signs as well as laboratory profileincluding

( Hb, TLC, PLT, Hct) on day 3, 5, 6&7 and dengue

serology was carried out.y The information was obtained on a pre-desgined

proforma and entered in to SPSS version. 18and thenanalyzed.


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RESULTS

y 212 pts had dengue fever, 39 had DHF, 3 had unusual

dengue.

y Headache, backache, abdominal pain was more

significantly associated with DHF than DF.

y Conversely, Epistaxis was more significantly associated

with DF

DHF.


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RESULTSDF n = 88 DHFn = 37 P ValueAge 8.92 3.6 9.05 3.1 0.844

Gender Male

Female50 (56.8%)

38 (43.2%)

21 (56.8%)

16 (43.2%)

0.995

Fever HC

HI83 (94.3%)

5 (5.7%)

35 (94.6%)

2 (5.4%)

0.951

Fever Duration 6.6 3.9 7.8 3.6 0.108

Headache 71 (80.7%) 36 (97.3%) *0.016

Bodyaches 68 (77.3%) 34 (91.9%) 0.054

Backaches 59 (67.0%) 34 (91.9%) *0.004

Abdominal Pain 27 (30.7%) 21 (56.8%) *0.006

Retro-orbital Pain 17 (19.3%) 29 (78.4%) < 0.001

Nausea 5 (5.7%) 1 (2.7%) 0.477

Vomiting 38 (43.2%) 12 (32.4%) 0.263

Diarrhea 4 (4.5%) 0.0 0.187

Arthalgia 2 (2.3%) 0.0 0.355

Rash 14 (15.9%) 7 (18.9%) 0.681

Convalescent 1 (1.1%) 0.0 0.515

Epistaxis 38 (43.2%) 2 (5.4%) *


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RESULTS

0

50

100

150

200

250

DF DHF UDF

DF

DHF

UDF


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RESULTS

%AGEOFDIFFERENTMANIFESTATIONS

DF

DF WITHHEMORRHAGE

DHF

DHSS

UDF


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DISCUSSION

y Mean age in our study was 8.9 3.7yrs as comparedto 9.8 4.2 yrs1.

y In our study %age ofDF/DHF was 86/15.3 ascompared to 31/69% 2.

1. KAZUNORIET AL, JAPAN

2. JOEL NAVAQRRETE-ESPINOSA; SOLUD PUBLICADEMEXICO/VOL.47,NO.3MAYO JUNIODE2005


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DISCUSSION

y Most common symptom in our study was headacheas compared to vomiting1.

y Epistaxis was significantly more prevalent in DFthan DHF, it is similar in other study but difference

was not significant2.

1. MAIMOONAM. AHMED; J INFECT DEV CTRIES 2010, 4(8) 503-510

2. VINOD H.RATAGERI ET AL INDIAN JOURNAL OF PEDIATRICS VOL. 72,AUG 2005.


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CONCLUSION

y Headache,bodyache, backache are moresignificantly associated with DHF than DF, however,epistaxis is significantly associated DF than DHF.


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LIMITATIONS

y It is a hospital based study , so , results can,t beextrapolated to whole poulation.

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New Clinical Profile of Children With Dengue Infection

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