UNIVERSITY of PENNSYLVANIA Tuesday, January 30, 2001 Volume 47 Number 20 www.upenn.edu/almanac/ IN THIS ISSUE 2 Senate: SEC Actions; Speaking Out: UCNS Appeal 3 Honors & Other Things; Death of Leonard Davis; Computer Recycling and Disposal 4 From Maps to Medicine: The Impact of the Genome Project (Beverly Emanuel) 6 HERS 2001 Info Session; EHRS Training; Infertility Discussion at Radnor 7 Mummenschanz; Update; CrimeStats; Classifieds 8 W-2 Form for Calendar Year 2000 Pullout: February AT PENN NFL Charities, an organization of the mem- ber clubs of the National Football League, has awarded a $110,000 grant to Penn’s Head Injury Center (HIC) to study the long-term effects of concussions. Concussions have always plagued physical sports, where contact is part of the game. But football players, such as Troy Aikman and Steve Young, are only among the most visible of the two million Americans that suffer from trau- matic brain injuries (TBIs) each year. “People rarely associate concussions with what they really aretraumatic brain injuries,” said Dr. Tracy K. McIntosh, the Robert A. Groff Professor of Neurosurgery and Director of the Head Injury Center. “Brain injury is a silent epidemic in this country, affecting more lives than most people realize.” In fact, the statistics surrounding traumatic brain injuries are staggering. According to num- bers compiled by the Brain Injury Association, approximately 5.3 million Americans—slightly more than 2% of the U.S. populationare living with a disability as a result of a severe brain injury. TBI is the leading cause of death and disability in persons under 45 years old, occur- ring more frequently than breast cancer, AIDS, multiple sclerosis, and spinal cord injury. Each year, approximately 100,000 people die from TBI, and 500,000 more are permanently dis- abled. Every 15 seconds, someone, usually a young person, suffers from a brain injury. Despite these numbers, our understanding of the brain’s long-term response to injury is still incomplete. “A brain-injured patient may look stable, but cells are still dying. Realizing this is important in developing ways to recover, regen- erate, and stem the loss of brain tissue,” said Dr. McIntosh. “We hope that by understanding the molecular and cellular sequences of events after trauma, we’ll be able to determine when and where cells die in the brain and use that informa- tion to develop new therapeutic strategies to treat head injury.” The Penn Head Injury Center is one of seven nationally designated Head Injury Centers by NFL Charities Grant to Head Injury Center (continued on page 2) Implementing Energy Conservation A major energy conservation initiative has begun here on campus with two goals: to conserve energy and to minimize the impact of rising energy prices on Penn’s operating budget. We urge the entire University community to lend their support and cooperation in these efforts as we embark on this ambitious program. The emerging energy problem may be reminiscent of the energy crises of the seventies and eighties when Penn was seeking ways to cope with and solve the critical social and technological problems that developed in the nation’s energy consumption. The recent increases in fuel prices, coupled with energy market volatility, have had an alarming impact on consumers; the operating budgets in Facilities Services have also been strained by these conditions. Increased costs related to utilities such as steam and electricity could adversely affect the resources available to facilities to operate and maintain the campus buildings and grounds. In order to conserve energy throughout campus, we strongly recommend the following energy conservation measures to be adopted across campus. Energy Conservation Recommendations 1. Set thermostats, to 65 degrees when offices, classrooms, labs and other areas are occupied and turn them down further at the end of the workday, to 59 degrees when an area is unoccupied. While this may seem like a drastic measure, a significant reduction in energy consumption will result from this approach. By setting back the thermostat from 70 degrees to 65 degrees, energy consumption is significantly reduced. We apologize for any inconvenience and suggest that those accustomed to warmer indoor temperatures may wish to dress warmly and leave a sweater or jacket at work. 2. Remove any items which block vents or radiators to allow for air to flow freely. 3. Besides lowering thermostats, we urge everyone to help conserve electricity by turning off lights—both fluorescent and incandescent—as well as computers, moni- tors, printers, scanners, copiers and other office and lab equipment when not in use for an extended period—especially overnight and on weekends or whenever possible. If in doubt about the advisability of shutting down a piece of equipment, check with a supervisor first. 4. Notify Facilities/Operations and Maintenance of any excessive drafts around windows or doors that could be alleviated. If there is a window air conditioner in a window, make sure it is properly sealed during the winter months. 5. Keep all exterior doors and windows closed to minimize infiltration of cold outdoor air into the buildings. In cold weather, open shades or blinds to allow direct sunlight to heat your room with solar heat. In many cases this also eliminates the need for electric lighting. At night, close the shades or blinds to keep in the heat. 6. Also notify Facilities when any building is unoccupied or out of service. Facilities/Operations and Maintenance can be reached at (215) 898-5833. Facilities Services is also taking several additional steps to ensure that all heating and air conditioning systems are operating efficiently. These initiatives have been implemented in cooperation with representatives from the Schools, Centers and the Office of Environmental Health and Radiation Safety. Given current economic conditions and the drastic energy shortages we are beginning to experience as a nation, we can no longer afford to take energy for granted. Hopefully, we can join together in implementing a wise, sensitive and forward-thinking energy conservation plan. The concerted dedication and determination of the faculty, staff and students to actively participate in saving energy and resources will help enormously. The occupants of Penn’s many buildings each play a vital role in ensuring the best outcome for Penn as well as the environment. Controlling energy costs is something that we must do individually and collectively to maximize energy-related cost-avoidance. Thank you. —Omar Blaik, Vice President, Facilities Services
Transcript
UNIVERSITY of PENNSYLVANIA
Tuesday,January 30, 2001Volume 47 Number 20www.upenn.edu/almanac/
IN THIS ISSUE2 Senate: SEC Actions;
Speaking Out: UCNS Appeal3 Honors & Other Things; Death of Leonard Davis;
Computer Recycling and Disposal4 From Maps to Medicine: The Impact of the
Genome Project (Beverly Emanuel)6 HERS 2001 Info Session; EHRS Training;
Infertility Discussion at Radnor7 Mummenschanz; Update; CrimeStats;
Classifieds8 W-2 Form for Calendar Year 2000
Pullout: February AT PENN
NFL Charities, an organization of the mem-ber clubs of the National Football League, hasawarded a $110,000 grant to Penn’s Head InjuryCenter (HIC) to study the long-term effects ofconcussions.
Concussions have always plagued physicalsports, where contact is part of the game. Butfootball players, such as Troy Aikman and SteveYoung, are only among the most visible of thetwo million Americans that suffer from trau-matic brain injuries (TBIs) each year.
“People rarely associate concussions withwhat they really aretraumatic brain injuries,”said Dr. Tracy K. McIntosh, the Robert A. GroffProfessor of Neurosurgery and Director of theHead Injury Center. “Brain injury is a silentepidemic in this country, affecting more livesthan most people realize.”
In fact, the statistics surrounding traumaticbrain injuries are staggering. According to num-bers compiled by the Brain Injury Association,approximately 5.3 million Americans—slightlymore than 2% of the U.S. populationare livingwith a disability as a result of a severe braininjury. TBI is the leading cause of death anddisability in persons under 45 years old, occur-ring more frequently than breast cancer, AIDS,multiple sclerosis, and spinal cord injury. Eachyear, approximately 100,000 people die fromTBI, and 500,000 more are permanently dis-abled. Every 15 seconds, someone, usually ayoung person, suffers from a brain injury.
Despite these numbers, our understanding ofthe brain’s long-term response to injury is stillincomplete. “A brain-injured patient may lookstable, but cells are still dying. Realizing this isimportant in developing ways to recover, regen-erate, and stem the loss of brain tissue,” said Dr.McIntosh. “We hope that by understanding themolecular and cellular sequences of events aftertrauma, we’ll be able to determine when andwhere cells die in the brain and use that informa-tion to develop new therapeutic strategies totreat head injury.”
The Penn Head Injury Center is one of sevennationally designated Head Injury Centers by
NFL Charities Grant toHead Injury Center
(continued on page 2)
Implementing Energy ConservationA major energy conservation initiative has begun here on campus with two goals: to
conserve energy and to minimize the impact of rising energy prices on Penn’s operatingbudget. We urge the entire University community to lend their support and cooperation inthese efforts as we embark on this ambitious program. The emerging energy problem may bereminiscent of the energy crises of the seventies and eighties when Penn was seeking waysto cope with and solve the critical social and technological problems that developed in thenation’s energy consumption.
The recent increases in fuel prices, coupled with energy market volatility, have had analarming impact on consumers; the operating budgets in Facilities Services have also beenstrained by these conditions. Increased costs related to utilities such as steam and electricitycould adversely affect the resources available to facilities to operate and maintain the campusbuildings and grounds.
In order to conserve energy throughout campus, we strongly recommend the followingenergy conservation measures to be adopted across campus.
Energy Conservation Recommendations1. Set thermostats, to 65 degrees when offices, classrooms, labs and other areas are
occupied and turn them down further at the end of the workday, to 59 degrees when anarea is unoccupied.
While this may seem like a drastic measure, a significant reduction in energyconsumption will result from this approach. By setting back the thermostat from 70degrees to 65 degrees, energy consumption is significantly reduced.
We apologize for any inconvenience and suggest that those accustomed to warmerindoor temperatures may wish to dress warmly and leave a sweater or jacket at work.
2. Remove any items which block vents or radiators to allow for air to flow freely.
3. Besides lowering thermostats, we urge everyone to help conserve electricity byturning off lights—both fluorescent and incandescent—as well as computers, moni-tors, printers, scanners, copiers and other office and lab equipment when not in use foran extended period—especially overnight and on weekends or whenever possible. Ifin doubt about the advisability of shutting down a piece of equipment, check with asupervisor first.
4. Notify Facilities/Operations and Maintenance of any excessive drafts aroundwindows or doors that could be alleviated. If there is a window air conditioner in awindow, make sure it is properly sealed during the winter months.
5. Keep all exterior doors and windows closed to minimize infiltration of coldoutdoor air into the buildings. In cold weather, open shades or blinds to allow directsunlight to heat your room with solar heat. In many cases this also eliminates the needfor electric lighting. At night, close the shades or blinds to keep in the heat.
6. Also notify Facilities when any building is unoccupied or out of service.Facilities/Operations and Maintenance can be reached at (215) 898-5833.
Facilities Services is also taking several additional steps to ensure that all heating and airconditioning systems are operating efficiently. These initiatives have been implemented incooperation with representatives from the Schools, Centers and the Office of EnvironmentalHealth and Radiation Safety.
Given current economic conditions and the drastic energy shortages we are beginning toexperience as a nation, we can no longer afford to take energy for granted. Hopefully, we canjoin together in implementing a wise, sensitive and forward-thinking energy conservationplan.
The concerted dedication and determination of the faculty, staff and students to activelyparticipate in saving energy and resources will help enormously. The occupants of Penn’smany buildings each play a vital role in ensuring the best outcome for Penn as well as theenvironment. Controlling energy costs is something that we must do individually andcollectively to maximize energy-related cost-avoidance.
Appeal to the Penn CommunityI write out of urgent concern for the
University City New School (UCNS).This independent school (Pre-K-8thgrade) was founded in 1974 to providequality, progressive education to the ra-cially and economically diverse commu-nity of West Philadelphia. UCNS hasbeen located for 25 years on Universityproperty (42nd and Locust) where it hasserved the families of hundreds of Pennfaculty and staff. It has also served theUniversity—by retaining families in WestPhiladelphia who would otherwise haveleft for the suburbs.
Today, the UCNS is financially sol-vent with an annual budget of $800,000.Its staff of 20 includes teachers of the 3Rs, plus computer, music, art, dance, andforeign language. The school remains trueto its founding goals of economic and racialdiversity.
In July, UCNS must vacate its long-termhome to make way for the Penn-assistedpublic school to be built on that site. ThePenn-assisted school promises to be an im-portant addition to West Philadelphia, butits catchment area will leave large areasunserved. Thus, it seems crucial to preservethe existing school that has served so wellover more than a quarter of a century.
UCNS has found a wonderful new homeon the ground floor of Calvary Church at48th & Baltimore Avenue. Architect JohnHolland has designed new classrooms, li-braries, etc.—more and better space—andthe UCNS Board assembled a package of$350,000, including a significant contribu-tion from Penn, to pay for the renovations.
But the school now encounters an un-foreseen obstacle. On January 15 the city’sZoning Board informed UCNS that anoccupancy permit will require air condi-tioning and sprinklers—costing another$100,000.
UCNS urgently seeks your help. Do-nations are needed, both small and large.These funds must be raised immediatelyso that the whole deal can proceed andbuilding can start. If not, parents will soonbe forced to look for other schools.
The goal could be reached quickly ifmembers of the Penn community willhelp. Realize that the quality of life andphysical safety in neighborhoods sur-rounding Penn depend—not just on betterlighting and tighter security—but also onbuilding and preserving an inhabitablecommunity. Please join me today in help-ing to preserve this school.
— Peter Sterling, Founding ParentAdvisor to the UCNS Board
Professor of NeuroscienceP.S.: Your donation is tax-deductible.Checks should be made to: UCNS(labeled “UCNS on the move”)4201 #1C Spruce St., Phila., PA 19104
The following statement is published in accordance with the Senate Rules.Among other purposes, the publication of SEC actions is intended to stimulate discussionamong the constituencies and their representatives. Please communicate your comments toSenate Chair Larry Gross or Executive Assistant Carolyn Burdon, Box 12 College Hall/6303,(215) 898-6943 or [email protected].
Actions Taken by the Senate Executive CommitteeWednesday, January 17, 2001
1. Chair’s Report. Faculty Senate Chair Larry Gross reminded SEC that he is working withPaul Mosher to raise consciousness about the state of scholarly publishing. Appointment of the JointSenate-Administration committee to assess methods of teaching evaluation is moving forward.Professor Gross noted that this is probably the last time SEC will meet at the Faculty Club and hethanked the Club for its help and for use of the space. SEC will begin meeting in a new conferenceroom in College Hall.
2. Past Chair’s Report on Academic Planning and Budget and Capital Council.Professor Phoebe Leboy stated that the December 12 meeting of Academic Planning and Budget wascancelled, and the next meeting is scheduled for January 23. The only action taken by CapitalCouncil in the past month was consideration of the financial implications surrounding leasing offacilities for the planned “Wharton-West” in the San Francisco area.
3. Chair of the Senate Committee on Committees. Faculty Senate Chair-elect David B.Hackney was elected by acclamation.
4. Proposed Revision of the Almanac Guidelines. Martin Pring, Chair, Senate Commit-tee on Publication Policy for Almanac, introduced the proposed minor and substantive revisions tothe Guidelines. He drew attention to changes under the section “As Publication of Opinion” whichprovide that the Almanac editor can determine that part or all of a contribution is irrelevant orunsuitable for publication and can require appropriate changes. The other substantive revision limitsletters to 400 words. These revisions call for the editor to consult with the Senate Committee onPublication Policy for Almanac. An appeal is provided for the contributor.
A motion was made to endorse the proposed revisions. The motion was adopted unanimously.The proposals will now go to the Almanac Advisory Board for discussion and action.
5. 1999-2000 Report and Recommendations and Policy Issues of the SenateCommittee on the Economic Status of the Faculty. Committee Chair Ed Boe presented thedocuments (to be published in Almanac next month). Senate Chair Larry Gross emphasized that theadministration is more forthcoming with more data than in the past and appreciates the committee’sefforts. Professor Gross was encouraged by inclusion of the Faculty Senate Chair and the CommitteeChair in discussions with the deans for the first time.
A motion was made to approve and endorse the report and the recommendations and policyissues. The motion was adopted unanimously.
Professor Gross extended appreciation and thanks to Ed Boe for his enormous amount of workand creativity, noting that he has raised the bar for faculty salary analysis.
the National Institutes of Health. As Director ofPenn’s Head Injury Center, Dr. McIntosh andhis colleagues and collaborators in Neurosur-gery, Bioengineering, Pharmacology and Pa-thology at Penn have made great progress inunderstanding and treating traumatic brain in-jury.
Their accomplishments include the discov-ery of the first link between traumatic braininjury and the development of post-traumaticepileptic seizures. They were also the first labo-ratory to identify the contribution of programmedcell death, called apoptosis, in mediating theprogressive cascade of cell death observed afterTBI. Dr. McIntosh and his colleagues have alsopioneered research into the mechanistic rela-tionship between head injury and Alzheimer’sDisease and other neurodegenerative disordersand were the first to evaluate the efficacy of
neural stem cell transplantation as a potentialtherapy for traumatic brain injury. Funding fromthe NFL Charities grant will support Dr.McIntosh’s efforts in furthering this progress.
To learn more about the Penn Head InjuryCenter, see their web site: bioeng.seas.upenn.edu/tbilab/.
NFL Charities is a nonprofit organizationthat was formed in 1973 by the 31 member clubsof the National Football League to enable theteams to collectively contribute to charitableand worthwhile causes on a national level. Sinceits inception, the Board of Directors of NFLCharities has agreed to grant over $40 million toover 250 different organizations.
The current Board of Directors includesMichael Bidwill, Hon. Jack Kemp, Jeffrey Lurie,John Mackey, Commissioner Paul Tagliabue,Delores Barr Weaver, and Ralph C. Wilson, Jr.
NFL Charities Grant to Head Injury Center(continued from page 1)
Speaking Out
Speaking Out welcomes readercontributions. Short timely letters onUniversity issues can be accepted, byThursday at noon for the following
Tuesday’s issue, subject to right-of-replyguidelines. Advance notice of intention to
Computer Recycling and DisposalRecycling and disposal of older computer
equipment is an issue of increasing importanceto departments at Penn. Beyond the basic need toclear space in closets or make room for newequipment there are specific concerns regardingenvironmentally safe disposal and, in many cases,a desire to see systems that still function put togood use in the community. As a starting pointfor local support providers who need to get rid ofold equipment, below are a few recommenda-tions for preparing equipment for recycling ordisposal and services that accept equipment do-nations from departments at Penn.Preparing Equipment for Recycling
The following recommendations are fromDave Millar, Information Security Officer:Delete Data from Drives and Storage Media
“When selling or donating old computers, besure to remove any sensitive data, and make surethat by leaving any commercial software on themachine you are not violating the terms of anysoftware license agreements. Note that files de-leted through ordinary means (e.g. dragging tothe trash on Windows or Macintosh) can usuallybe recovered. Use a secure file deletion utilitywhich ensures that the data can not be recoveredby successively writing binary ones and zerosover files to be deleted. Pretty Good Privacy(PGP) includes a secure delete function and isfreely available for non-commercial use forWindows and Macintosh at web.mit.edu/net-work/pgp.html. Norton Utilities’ Wipe Info fea-ture will also securely delete files.
“The same advice applies to storage medialike computer tapes, disks, diskettes, etc. Be sureto completely remove any sensitive informationbefore disposing of electronic storage media.University Archives and Records offers a ser-vice for secure destruction of confidential elec-tronic records. See www.archives.upenn.edu/home/URC.html. If you need further help find-ing tools or services to do this, contactsecurity@ isc.upenn.edu.”Check Software Licenses
“Before transferring computers containing anysoftware, first make sure that Penn is properlylicensed to transfer it, that it was not obtainedillegally or in violation of license terms, and that thesoftware was never copied illegally or in violationof license terms. Make sure that the transfer con-forms with terms of the software license.”Computer Donations Programs
The following accept equipment from depart-ments, recycling or disposing of it as appropriate:
Penn’s Center for Community PartnershipsContact: Isabel Sampson-Mapp orCory Bowman at (215) 898-2020.GoodwillContact: Bob Mattson at (610) 777-7875 x262.Dell Financial Services offersAsset Recover Services.
Environmental RegulationsThere are specific EPA guidelines for dis-
posal of some equipment components. In addi-tion, there may be other regulations imposed atthe state or local level.The Pennsylvania Depart-ment of Environmental Protection web site dis-cusses Electronic Discards within their House-hold Hazardous Waste web site, but it’s not clearthe same rules would govern disposal at Penn.
Local organizations such as Nonprofit Tech-nology Resources (which is utilized by Penn’sCenter for Community Partnerships) appear totake care of the potential hazards indentified bythe EPA in disposing of computers. Penn’s Cen-ter for Community Partnerships is also workingwith Elemental Inc., a local electronics salvager.
Death
Mr. Davis, Founder of LDILeonard Davis, founder of the Colonial Penn
Group, founder of the Leonard Davis Institute ofHealth Economics and philanthropist, died onJanuary 15 at the age of 76. Mr. Davis foundedColonial Penn Group in 1963, which becameone of the country’s largest insurance under-writers for older Americans. Mr. Davis—alongwith his wife Sofie—was instrumental in thefounding of the Leonard Davis Institute. Theinstitute was established in 1967 in response toa growing national need for high quality re-search and education to inform policies criticalto the financing and management of the nation’sincreasingly costly and complex health care sys-tem. The Leonard Davis Institute remains one ofthe only research institutes in the country thatintegrates medicine, nursing and managementexpertise and applies it to solving the health careissues of the day.
He received an honorary Doctor of Lawsdegree from Penn in 1972. The citation read:
With the bold, forthwright spirit of a manwith a cause, Leonard Davis pioneered grouphealth insurance for the aged against formi-dable odds. As an initiatior of a new fieldand the founder of a needed range of ser-vices for retired persons, he assisted a large,neglected group, showing that the practicalvisionary is our best Samaritan.Of strong and imaginative socal conscience,he early ascertained that problems in healthcare could be helped through coordinationwith the resources of management sciences.The resulting Wharton M.B.A. program inHealth Care Administration and the LeonardDavis Institute of Health Economics havemade our coalescence of medicine andmanagement a prototype for similarmultidisciplinary efforts in other fieldsand at other universities.His own healthy outlook and his vigorousenergy have illustrated to the less fortunateand the skeptical that taking chances is themost useful of new beginnings. The Trust-ees of the University, believing themselvesfortunate to have his counsel, ask that he berecognized with the honorary degree, Doc-tor of Laws.Mr. Davis is survived by sons Alan and
Michael; and four grandchildren.
Honors & Other Things
Big 5 Hall of Fame InducteeChuck Daly, former Penn basketball coach,
was inducted last Saturday into the Big 5 Hall ofFame. Mr. Daly came to Penn in 1971 andguided Penn to a 125-38 record during his sixseasons here. During that time, the Quakers alsowon four Ivy League Championships and madefour trips to the NCAA Tournament. He went onto successfully coach in the NBA. Mr. Daly alsocoached the gold-medal winning “Dream Team”in the 1992 Olympics in Barcelona. He wasinducted into the Naismith Memorial BasketballHall of Fame in 1994, into the Penn Hall of Famein 1998, and is listed as one of the Top 10 NBACoaches of all-time. He is listed as the 15thwinningest coach in NBA history.
Two AICP FellowsPresident Emeritus and University Profes-
sor Emeritus Martin Meyerson, and Dr. AnthonyR. Tomazinis, professor of city and regionalplanning, were recently elected Fellows of theAmerican Institute of Certified Planners.
MLK AwardsThis year’s Martin Luther King Community
Service Award winners were announced at a cer-emony on January 18.
Robert Alsbrooks, a senior programer at theCenter for Clinicial Epidemeology and Biosta-tistics, received the Employee Award. Mr.Alsbrooks helped to develop and is the directorof Miracle on 34th Street, an organization thathelps people deal with social issues and hasinitiated a track team, and boys and girls groups.He takes an active part in Turn Around Mantuato board up illegal drug houses, clean the streets,work with local law enforcement with commu-nity policing and lectures to the community andvarious local and national agencies on entrepre-neurial ventures and its positive impact on drugand crime reduction.
Dr. Esaul Sanchez, director of Neighbor-hood Initiatives, also received the EmployeeAward. He has helped the community surround-ing Penn to improve security in the neighbor-hoods, revitalize the block captain program andcreated a network of landlords. He was part of ateam who worked with neighbors to install morethan 2,500 outdoor lights in the various neigh-borhoods in West Philadelphia. He founded andmanages UC Green, which promotes, coordi-nates and supports with its partners, projects thatrealize a cohesive vision of Greening in Univer-sity City’s diverse urban neighborhoods.
Yael Krigman, Col’02, received the StudentAward. She is also the director of the Philadel-phia office of National Student Partnerships(NSP), a non-profit organization which helpsand empowers the people of the community tofind the jobs, resources, and services necessaryto overcome the barriers which prevent themfrom reaching their goals.
Kevin E. Vaughan, Col’77, received the Com-munity Award. Mr. Vaughan, former Region IIIDirector at the U. S. Department of Health andHuman Services, uses his community networkto forge solutions while tackling complex issuessuch as outreach for the State Children’s HealthInsurance Program (S-CHIP) and access to qual-ity childcare.
Kamau McRae, a case manager at the BreslinLearning Center, also received the CommunityAward. A life-long Philadelphia resident, Mr.McRae has always striven to better the worldaround him. His community service began dur-ing his undergraduate years at Penn State at theWomen’s Resource Center as a domestic vio-lence and sexual abuse counselor. Mr. McRaecontinued to be a role model for young menthrough his volunteer work with Blacks Educat-ing Blacks About Sexual Health Issues(BEBASHI) and the Father’s Day Rallying Com-mittee in Philadelphia.
Ivy Leaders SummitLaura Breyfogle, a freshman in the School of
Nursing, has been selected to attend the IvyLeaders Summit at Harvard University in Febru-ary. Ms. Breyfogle, a Massachusetts native, iscurrently the treasurer of the student nurses group.
Hollywood Squares BoundJoey Tini, a freshman in the School of Nurs-
ing and a native of South Philadelphia, will beappearing on the TV game show HollywoodSquares on February 20.
I would like to speak to you on behalf of the numerous scientists involvedin the human genome initiative as well as my fellow geneticists, the individualswho will apply the fruits of the Genome Project to medical practice. Thiswonderful occasion gives me the opportunity to provide you with somebackground about the program and to speculate a bit about what changes theGenome Project will make to the practice of medicine in the future.
It is particularly fitting that I speak to you on the occasion of the celebrationthe 295th birthday of Benjamin Franklin, a scientist, inventor and revolution-ary thinker! It was Franklin who so aptly stated that “the doors of wisdom arenever shut”, a concept which exemplifies both the current approach toscientific discovery as practiced within the medical institutions of our extraor-dinary city and the nature of the Genome Project itself. The celebration of the250th anniversary of the founding of the Pennsylvania Hospital by BenjaminFranklin and Dr. Thomas Bond, honors another exemplary Philadelphiainstitution, another facet of the University of Pennsylvania Health System,where I am a faculty member.
I personally feel very much a part of the Benjamin Franklin story, althoughfor fewer years than the 250 or 295, because I was born and raised inPhiladelphia which means that the Franklin Institute (one of my favorite sitesas a child), the Benjamin Franklin Parkway, the Benjamin Franklin Bridge andFranklin Field were all a part of my daily life. Further, my father, husband,children and I are all graduates of Franklin’s University, the University ofPennsylvania, which was founded in 1740. Finally, when my 25thPenn classreunion was held, our class gift to the University was the wonderful GeorgeLundeen bronze statue fondly called “Ben on the Bench”. Many of us have satwith Ben and pondered the remarkable changes that have taken place since hewalked the streets of Philadelphia. Thus, my Franklin ties go much deeper thanthe use of bifocals and odometers in my own daily life.
Many of you might be wondering—what is the Human Genome Project?The Genome Project is an exciting international, collaborative scientific effortdesigned to identify, analyze, and determine how all the genes in the humanbody are organized. The enormous amount of knowledge it will produce willmake it possible to understand and modulate the genetic causes of disease andhelp keep people “disease free.” The result of this monumental undertakingwill be to provide us with a complete blueprint for each of the 100 trillion cellswhich make up the human body. So in the past 25+ years, the once-obscurediscipline of molecular genetics has become the central science of medicine.At the heart of genetics is DNA or deoxyribonucleic acid—an extraordinarilylong chemical molecule shaped like a twisted ladder. This double helix,deciphered by Watson and Crick in 1953, provides the instructions foreverything a cell does—including causing disease. If we’re trying to under-stand something at its most basic level, it makes sense to go and read theinstructions, determine the sequence of the genes. This is why one of the goalsof the Genome Project is to complete the sequence of the Human Genome.
Genes determine many of our features, such as eye and hair color, but genescan also be responsible for causing many diseases or predisposing us todevelop disease. It is estimated that each of us has approximately 50-100,000genes in our genomes. Each of these genes has the potential for being a diseasegene if it contains an error in its DNA sequence. The successes of the HumanGenome Project (HGP) have even enabled researchers to pinpoint errors ingenes—the smallest units of heredity—that cause or contribute to disease.
The ultimate goal is to use this information to develop new ways to treat,cure, or even prevent the thousands of diseases that afflict humankind. But theroad from gene identification to effective treatments is long and fraught withextraordinary challenges. In the meantime, biotechnology companies areahead of the game with their commercialization of the Genome Project. Suchcompanies are designing diagnostic tests to detect aberrant genes in peopleeither suspected of having a particular disease or those individuals at risk fordeveloping them. Genetic testing has become an increasingly important toolin medical practice.
DNA-based tests are amongst the newest and most sophisticated of thetechniques used to identify genetic disorders. They involve direct examinationof the DNA molecule itself. Genetic tests are used for several reasons,including: carrier screening, prenatal diagnosis, and newborn screening. Theyare also used for presymptomatic testing for predicting adult-onset disorderssuch as Huntington’s disease. Alternatively they are used for presymptomatictesting for estimating the risk of developing such diseases as a variety of adult-onset cancers and Alzheimer’s disease. The recently commercialized genetests for such adult-onset disorders (such as Alzheimer’s disease and cancerspredisposition) are the subject of much of the debate over gene testing. One ofthe most serious limitations of these susceptibility tests is the difficulty ininterpreting a positive result because some people who carry a disease-
associated mutation never actually develop the disease.This is a complex issue because, in a broad sense virtually all disease has
a genetic component. The vast majority of people never develop skin cancer,yet we all have at least a slight genetic predisposition for it. Given enoughexposure to sunlight, nearly all of us would develop it. Thus, even though thesun’s ultraviolet radiation is primarily responsible, our genetic makeup is asmall but real contributor to the disease. However, there are some people whowould get skin cancer even if they never went out in the sun. Their geneticstructure is 100% responsible for the disease in the absence of sun exposure.
Even infectious illnesses may have an inherited component. Most peopleexposed to the human immunodeficiency virus develop AIDS. But somepeople exposed to the virus do not develop the disease, presumably becausethey have inherited a gene which confers immunity to the virus. Decipheringthis underlying genetic component to many diseases is one of the aspects thatmakes the Human Genome Project so exciting.
The easiest genetic diseases to understand are those caused by a single genethat has gone awry. Single gene diseases include relatively rare disorders suchas cystic fibrosis, phenylketonuria, hemophilia, sickle cell anemia andHuntington’s disease. In a sense, the genes for these diseases act like a singletime bomb ticking away inside the DNA double helix.
Much more common, and far more complicated, are the diseases caused bymalformations in several or many genes that influence each other in complexways that are poorly understood. Hypertension, diabetes, rheumatoid arthritis,multiple sclerosis, schizophrenia, Alzheimer’s, coronary artery disease andnumerous other diseases that afflict our species are caused by the interactionsof multiple different genes. Each individual gene has a relatively modesteffect, but together they determine whether someone is going to develop adisease or not. Multiple gene diseases or what we call polygenic diseases arefar harder to understand than those which are caused by single genes.
Complicating matters even further, most genetic diseases result from aninterplay between an inherited predisposition and factors in a person’s externalenvironment and lifestyle. It’s not just the individual cards that you have beendealt, but it also depends upon how you play the hand. It’s important to keepthis in mind to avoid the dangers that can potentially arise from biologicaldeterminism—thinking that everything about an individual is predeterminedby the DNA code written in his or her genes.
The DNA is located inside the cell nucleus. As I mentioned, the DNA is inthe shape of a double helix which is wound over and over again. Unwindingit reveals the two strands that make up the sides of what is essentially a ladder-shaped molecule. The ladder’s rungs are called base pairs and there are 3billion base pairs of DNA in the human genome. The DNA is organized intoindividual units, called chromosomes. In humans there are a total of 46chromosomes in each cell. There are 22 pairs of chromosomes which aredesignated as autosomes–chromosomes 1 through 22 and a pair of sexchromosomes, XX for females and XY for males.
For many years, in fact since the mid-fifties scientists have been able tolook at the chromosomes at the microscope, count them and analyze them. Infact, in a clinical setting, many chromosome tests are performed to determinethe genetic or chromosomal composition of an individual.
At present, despite the fact that we can see all of the chromosomes andanalyze their composition in a gross sense, we have only identified thecomplete workings of a fraction of the genes which reside on them. One of thegoals of the human genome initiative is to identify the tens of thousands ofremaining genes, to isolate them and characterize what they do after assigningthem to their precise positions on chromosomes.
Such efforts have already been successful in the search for the cysticfibrosis gene and in the search for the genes responsible for neurofibromatosis,muscular dystrophy, fragile-X linked mental retardation and myotonic dystro-phy, some of the earliest disease genes to be identified. The list of identifieddisease related genes now grows on a daily basis. However, many additionaldiseases with their respective disease-causing genes remain to be successfullyidentified and characterized.
In order to accomplish this task, it was necessary to make maps of thehuman genome. Making maps of the human genome is not very different frommaking the maps that we are all familiar with. For example, if all that existedwas an outline map of the United States and I asked someone who didn’t knowthe geography of the United States where the location of a particular city was,it would be difficult without some roads or markers to help find the way. Thesame would be true of asking someone about the location of a particular newdisease locus. It requires the assistance of a map.
Now if you looked at the same map with one road, for example Route 80,(continued past insert)
From Maps to Medicine: The Impact of the Genome Projectby Dr. Beverly S. Emanuel, Director of Human Genetics Center; Charles E. H. Upham Chair in Pediatrics
The following is Dr. Emanuel’s keynote address at the recent dinner in Celebration! Benjamin Franklin, Founder
ALMANAC January 30, 2001 5www.upenn.edu/almanac
which moves from coast to coast—from Philadelphia to San Francisco. If youwere able to say that a gene was on the that road, it would help slightly, becauseyou would have narrowed the search for figuring out precisely where that geneis located. However, if we were to mark the length of that road with 15 evenlyspaced cities, or markers, it would be a different story.
In this case, if you said that the place in question, or the gene in question,was between Chicago and Des Moines and east of the Mississippi River, youwould have narrowed the search for that place or that particular geneconsiderably. You would then know precisely where to look on the map.
This was one of the very first goals of the human genome initiative, to placea series of evenly spaced, “markers” on all of the chromosomes. These markerspermit geneticist to determine where a particular disease gene is located, evenif we do not know what the normal gene does. We do this by studying familiesthat manifest the disease and seeing how the markers are inherited inassociation with the disease in affected families. These are what we refer to asgenetic maps.
Physical maps permit us to look at a different view of the genome and thesemaps are much more detailed than genetic maps. These maps are made byanalysis of the chromosomal DNA directly by isolating it and then sequencingit. For this type of map making we start with a particular chromosome, take thechromosome apart by isolating the DNA or genetic material from thatchromosome and then put it back together in an ordered array. In the interim,we are able to study each individual fragment in greater detail. That is likemaking very detailed maps with precise addresses, street names and the like.
Why do we want to map the human genome? Because, this concerted effortwill simplify the process and has already hastened efforts directed towardunderstanding the role that genes play in normal individuals and how genescause specific diseases when their role is altered. Understanding what genesnormally do will permit us to design more appropriate therapies, to correct theimpact of defective genes on health.
At Children’s Hospital and Penn we made the decision to map chromo-some 22. We chose chromosome 22 for historical and practical reasons. It isthe second smallest of the human chromosomes, being comprised of some-where less than 50 million base pairs, or megabases of DNA. We wanted toknow the answers to some very simple questions: What genes are onchromosome 22 and how are they arranged? Knowledge of the fundamentalanatomy of the human genome, and for us of chromosome 22, was importantto our ultimate goal of understanding how our body works when it is healthy,as well as when it is not healthy.
In addition chromosome 22 has a wealth of pathology associated with non-random chromosomal abnormalities providing us excellent source materialsfrom patients with chromosome 22 related diseases with which to build ourmaps and a rationale for making the maps. These are the practical reasons. Formany of us, it represented a logical extension of many years of scientific workwhich has focused on diseases caused by these abnormalities of humanchromosome 22.
For example, an abnormal chromosome 22 is associated with several formsof pediatric and adult leukemia. In 1960, chromosome 22 was named thePhiladelphia Chromosome by Drs. Peter Nowell and David Hungerford whenthey discovered its’ involvement in chronic myelogenous leukemia at Pennand the Fox Chase Cancer Center. In addition, a number of other birth defectrelated syndromes are associated with abnormalities of chromosome 22. Amissing piece of 22 or a deletion and an extra part of 22 or a duplication. Thesesyndromes were described by pediatric physicians and colleagues in Philadel-phia. Hence, we thought it would be appropriate that the Philadelphiachromosome be isolated, analyzed and understood in Philadelphia.
Eventually several of these disorders were studied in my laboratory. Littleby little we have made remarkable progress toward understanding why thissmall chromosome is so prone to disease related rearrangements. As anexample, I would like to briefly discuss our recent work related to one of theabnormalities of chromosome 22, the deletion which is associated with adiagnosis named DiGeorge syndrome or velocardiofacial syndrome. This is adefect which can afflict newborns with heart disease, immunologic defect,seizures cleft palate and learning differences. We found that this complicateddisease is the result of these children having a portion of one chromosome 22missing. We know how large the segment is, and that 30 genes are actuallydeleted. Understanding the organization of chromosome 22 has helped us tomore accurately diagnose this disorder because we have been able to designa DNA based genetic test which can now be utilized very early so that thediagnosis can be made when the child is an infant. This has some veryimportant ramifications for early therapeutic interventions to help the familiesof these children.
However, you can imagine that there might be some questions about thisand other disorders. Not all children with the deletion are equally severelyaffected. Thus, there are questions regarding what is normal and what is adisability or disorder, and who decides? We know that the children with the
deletion can have learning differences or speech difficulties. Are such disabili-ties diseases? Should they be prevented? Should they be “cured”? Doessearching for a cure demean the lives or the very existence of individualspresently affected by disabilities? Genetic information is a powerful tool forimproving our health, but it also can potentially be used in ways that areharmful. Protections against the misuse of genetic information are in place forcertain aspects of genetic testing, but much work remains to be done.
An increasing number of gene tests (such as this one) are becomingavailable commercially. Nonetheless scientists continue to debate the bestway to deliver them to the public and medical communities, often to individu-als that are unaware of their scientific and social implications. While some ofthese tests have greatly improved and even saved lives, scientists remainunsure of how to interpret many of them. Also, patients taking the tests facesignificant risks of jeopardizing their employment or insurance status. Further,because genetic information is shared, these risks can extend beyond theindividual who has been tested to other family members as well.
Within the next decade, researchers will find most human genes. Explora-tions into the function of each one—a major challenge extending far into the21st century—will shed light on how faulty genes play a role in diseasecausation. With this knowledge, commercial efforts will shift away fromdiagnostics and toward developing a new generation of therapeutics based ongenes. Drug design will be revolutionized as researchers create new classes ofmedicines based on an approach using gene sequence as well as proteinstructure function information rather than the traditional trial-and-error method.This new generation of drugs, targeted to specific sites in the body, promiseto have fewer side effects than many of today’s medications.
Human Genome Project scientists plan to finish the human sequence by2003 and establish database of the most common sequence variations thatdistinguish one individual from another. This knowledge base will revolution-ize biology and medicine. What will be different 20 years from now becausethe human genome was sequenced? How might my medical care differ as aresult of “genetic medicine?”
It is likely that virtually complete list of human genes will give us a vastrepertoire of potential new drugs. From the current repertoire of 500 or so drugsin 2000, at least six times this number will have been identified, tested, andcommercialized in the next 20 years. All will be manufactured by recombinantDNA technology so they will be significantly purer just as human insulin andgrowth hormone are today.
I predict that an individual’s medical record will likely include a catalogueof single base-pair variations that can be used to accurately predict responsesto certain drugs and environmental substances. This will permit a patient to betreated as a biochemical and genetic individual. This will make medicalinterventions much more specific, precise, and hopefully more successful. Inaddition, the increased power of geneticists to predict susceptibility to specificdiseases will allow an individual to alter his or her lifestyle to reduce thelikelihood of developing particular diseases or to be treated with preventive ordisease-delaying medications.
Some of the mysteries of early embryonic development will be solved. Weshould know the timing of expression of most, perhaps all, of the human geneset. We may have learned how to direct differentiation so that a desired celltype or even relatively “simple” organs and parts of more complex organs canbe grown for transplantation. In 20 years, we will have made substantialprogress towards true “cloning” of certain organs, but many difficult technicalsteps will probably remain before the successful cloning of a complex organlike a heart or liver.
So the Human Genome Project will have vast and largely positive impactson people living in 20 years from today. Of the various predictions I havediscussed, the knowledge about early embryonic development and genefunction is likely to be the most profound because often the most powerful andextensive impacts come from fundamental knowledge, usually in unforeseenways. As this astonishing treasure trove is introduced into society, we need tobe alert to the challenges of the possible misuses of this knowledge aboutourselves. Society as a whole, not just genome scientists or geneticists, mustaddress these considerations. It has to be all of us.
The information generated as a result of the Human Genome Project isexpected to be the encyclopedia or source book for biomedical science in the21st century. It will assist us in understanding and eventually treating many ofthe more than 4,000 genetic diseases that afflict man, as well as the numerousdiseases in which genetically-based predisposition plays an important role,heart disease and cancer to name just a few. This research will lead to improvedstrategies for preventing, diagnosing, and treating disease, and will bringgenetic medicine to the forefront of health care in the 21st century. Over theyears, we predict that as a result of this international effort, the genomeinitiative will produce great health benefits and will result in better health carefor millions of individuals who suffer from genetically based diseases and forfuture generations of children and their parents.
ALMANAC January 30, 20016 www.upenn.edu/almanac
EHRS Training Programs: February
To Penn Women:Have you heard about HERS and the Bryn Mawr
Summer Institute for Women in Higher Education?Ever think about applying? Wonder what the processis? Or want to know what the program is like? Comejoin us for an Information Session about the 2001HERS program. Talk with colleagues who have at-tended HERS in years past and find out about thisyear’s program and application process. The sessionwill be held Tuesday, February 6, 4:30-6 p.m. in room104, Logan Hall. An informal discussion will also takeplace on Wednesday, February 7, 5-6 p.m. in theLiving Room of the Inn at Penn.
The University will sponsor the nomination of twowomen to the Summer Institute for Women in HigherEducation Administration, sponsored by Bryn MawrCollege and Higher Education Resources (HERS) MidAtlantic and will fully fund their participation.
Over the years, Penn has supported the enrollmentof over 50 women faculty and administrators fromschools and departments across the campus. As in thepast, a review committee of several HERS alumnaeand Penn faculty will select the two nominees forrecommendation to HERS. (HERS makes the finalselections.)
Applications for those selected by the internal com-mittee will be forwarded to HERS for final review andacceptance in March. For an application or more infor-mation, contact Linda Wiedmann by e-mail [email protected] or visitwww.upenn.edu/penntrex/Institute/home.html.
2001 HERS Program Information Session: February 6
—Linda A. Wiedmann, Associate Director, Benjamin Franklin Scholars/General Honors,Center for Undergraduate Research and Fellowships
The following training programs are requiredby the Occupational Safety & Health Adminis-tration (OSHA), the Nuclear Regulatory Com-mission (NRC), and The Commonwealth ofPennsylvania (DEP), for all employees whowork with hazardous substances including:chemicals, human blood, blood products, fluids,and human tissue specimens and radioactivematerials. These programs are presented by theOffice of Environmental Health & RadiationSafety (EHRS). Attendance is required at one ormore session, depending upon the employee’spotential exposures.
Introduction to Laboratory Safety at Penn(Chemical Hygiene Training); provides a com-prehensive introduction to laboratory safety prac-tices and procedures at Penn and familiarizes thelaboratory employee with the Chemical Hy-giene Plan. This course is designed for employ-ees who have not previously attended Labora-tory Safety at the University. Required for allUniversity employees who work in laboratories.February 6, 1:30 p.m., CRB, Austrian Auditorium.
Introduction to Occupational Exposure toBloodborne Pathogens; this course provides sig-nificant information for employees who have apotential exposure to human bloodborne patho-gens. Topics include a discussion of the Expo-sure Control Plan, free Hepatitis B vaccination,recommended work practices, engineering con-trols and emergency response. This course isdesigned for employees who have not previ-ously attended Bloodborne Pathogens trainingat the University. Required for all Universityemployees potentially exposed to human bloodor blood products, human body fluids, and/orhuman tissue. February 13, 1:30 p.m., CRB,Austrian Auditorium.
Occupational Exposure to Bloodborne Patho-gens (In a clinical setting); required for allUniversity faculty and staff who have potentialclinical exposures to blood and other human
Q. What is the purpose of the Summer Institute?A. The Institute offers women faculty and administrators intensive training in education
administration pertinent to the management and governance of colleges and universities. It isdesigned to improve the status of women in middle and executive levels of higher educationadministration, areas in which women traditionally have been under-represented.Q. What are the main curricular areas?
A. The curriculum focuses on four areas: academic environment, external environment,institutional environment and professional development. Specific work areas include strate-gic planning, budgeting and accounting, financing higher education, and leadership skills.Q. Who makes up the faculty?
A. The faculty is comprised of women and men from government, foundations, profes-sional associations, and the diverse sectors of North American higher education.Q. Who is eligible to apply?
A. Application for admission is open to women faculty and administrators whosebackground, experience and present responsibilities indicate a potential for professionaladvancement in higher education administration.Q. When and where will the program be held?
A. The Institute, a residential experience in its 26th year, will be held from June 24 to July20, 2001 on the campus of Bryn Mawr College. Although most women live on campus, it ispossible to commute. Classes are held from approximately 8 a.m. to 4 p.m. Monday-Fridayand from 8 a.m.-noon on Saturday. There are programs and group discussions scheduled fora number of the evenings.Q. What is the application process?
A. Applicants must complete an application form and submit a letter of recommendation.For administrators, this letter should be from the department head or supervisor; for faculty,it should be from a faculty member who is knowledgeable of the candidate’s administrativeabilities. Submit materials to Linda Wiedmann, AWFA President , CURF, 2nd floor, ARCH,3601 Locust Walk, no later than Thursday, February 22.
source material. It is intended for employeeswith direct patient contact, or those who handleclinical specimens, and administrators who rou-tinely work in a clinical environment. Topicsinclude: risks, protection, work practice con-trols and emergency procedures. This course isdesigned for employees who have not previ-ously attended Bloodborne Pathogens trainingat the University. It is available on-line.
Laboratory Safety—Annual Update; this pro-gram is required annually for all laboratoryemployees who have previously attended Chemi-cal Hygiene Training. Topics include chemicalrisk assessment, recommended work practices,engineering controls and personal protection aswell as an update of waste disposal and emer-gency procedures. Faculty and staff who workwith human source materials, HIV or hepatitisviruses must attend the Laboratory Safety andBloodborne Pathogens—Annual Update. Feb-ruary 8, 9:30 a.m., BRB, Room 251.
Laboratory Safety and Bloodborne Patho-gens—Annual Update; this program is requiredannually for all faculty and staff who work withhuman source material, HIV or hepatitis virusesand have previously attended Occupational Ex-posure to Bloodborne Pathogens. Issues in gen-eral laboratory safety and bloodborne pathogensare discussed. Topics include bloodborne dis-eases, risk assessment, recommended work prac-tices, engineering controls and personal protec-tion as well as an update of waste disposal andemergency procedures. Participation in Labo-ratory Safety—Annual Update is not required ifthis program is attended. February 15, 9:30 a.m.,John Morgan, Class of 1962.
Radiation Safety Training—New Worker; thisprogram provides information on fundamentalradiation concepts and requirements for the use,storage and disposal of radioactive materials atPenn. Personnel working in laboratories whereradioactive materials are present are required to
attend this training before beginning their workfollowed by annual attendance at the trainingprogram described below. Training can be com-pleted on-line at (www.ehrs.upenn.edu) underRadiation Safety Programs, Training for Credit.
Radiation Safety Training—Annual Update;this program updates radioisotope users on cur-rent Radiation safety issues and practices. It isrequired of all personnel who work in areaswhere radioisotopes are used or stored. Trainingcan be completed on-line.
Radiation Safety Training—Irradiator Us-ers; individuals interested in becoming autho-rized to use an irradiator must first receive op-erational training from the irradiator licenseeand radiation safety training from EHRS. Train-ing can be completed on-line at (www.ehrs.upenn.edu) under Radiation SafetyPrograms, Training for Credit.
Additional programs will be offered on amonthly basis. Check the EHRS web site(www.ehrs.upenn.edu) for dates and time. If youhave any questions, please call Bob Leonzio at(215) 898-4453.
Infertility Discussion at RadnorThe Penn Center for Reproductive
Medicine and Surgery will hold an openhouse on February 6 from 7-8 p.m. in theAnnenberg Conference Room, 2nd floor,at 250 King of Prussia Road. Sponsoredby the Department of Obstetrics and Gy-necology at Penn Medicine at Radnor,this open house will feature a discussionby infertility experts Samantha Pheiferand Kurt Barnhart. Both Dr. Pheifer andDr. Barnhart are board certified in repro-ductive endocrinology and infertility aswell as obstetrics and gynecology. Theevent is free but registration is suggested.Call 1-800-789-PENN.
The University of Pennsylvania values diversity and seeks talentedstudents, faculty and staff from diverse backgrounds. The University ofPennsylvania does not discriminate on the basis of race, sex, sexualorientation, religion, color, national or ethnic origin, age, disability, orstatus as a Vietnam Era Veteran or disabled veteran in the administrationof educational policies, programs or activities; admissions policies; schol-arship and loan awards; athletic, or other University administered pro-grams or employment. Questions or complaints regarding this policyshould be directed to Valerie Hayes, Executive Director, Office of Affirma-tive Action,3600 Chestnut Street, 2nd floor, Philadelphia, PA 19104-6106or (215) 898-6993 (Voice) or (215) 898-7803 (TDD).
Suite 211 Nichols House3600 Chestnut Street, Philadelphia, PA 19104-6106Phone: (215) 898-5274 or 5275 FAX: (215) 898-9137E-Mail: [email protected]: www.upenn.edu/almanac/
The University of Pennsylvania Police DepartmentCommunity Crime Report
About the Crime Report: Below are all Crimes Against Persons and Crimes Against Society from thecampus report for January 15 through January 21, 2001. Also reported were 16 Crimes AgainstProperty: (including 10 thefts and 6 retail thefts). Full reports on the Web (www.upenn.edu/almanac/v47/n20/crimes.html). Prior weeks’ reports are also on-line.—Ed.This summary is prepared by the Division of Public Safety and includes all criminal incidents reported and madeknown to the University Police Department between the dates of January 15 and January 21, 2001. TheUniversity Police actively patrols from Market Street to Baltimore Avenue and from the Schuylkill River to 43rdStreet in conjunction with the Philadelphia Police. In this effort to provide you with a thorough and accurate reporton public safety concerns, we hope that your increased awareness will lessen the opportunity for crime. For anyconcerns or suggestions regarding this report, please call the Division of Public Safety at (215) 898-4482.
18th District Report8 incidents and 0 arrests (4 robberies, and 4 aggravated assaults ) were reported between January 15 andJanuary 21, 2001 by the 18th District covering the Schuylkill River to 49th Street and Market Street toWoodland Avenue.
The University of Pennsylvania’s journal of record, opinion andnews is published Tuesdays during the academic year, and asneeded during summer and holiday breaks. Its electronic edi-tions on the Internet (accessible through the PennWeb) includeHTML and Acrobat versions of the print edition, and interiminformation may be posted in electronic-only form. Guidelines forreaders and contributors are available on request.EDITOR Marguerite F. MillerASSOCIATE EDITOR Margaret Ann MorrisASSISTANT EDITOR Tina BejianSTUDENT INTERN Melissa KahaneSTUDENT ASSISTANTS Angie Liou; William YeohUCHS INTERN Shante Rutherford
ALMANAC ADVISORY BOARD: For the Faculty Senate, MartinPring (Chair), Peter Freyd, Larry Gross, David Hackney, PhoebeLeboy, Michael W. Meister, Joseph Turow. For the Administra-tion, to be named. For the Staff Assemblies, PPSA , MicheleTaylor; Karen Pinckney, A-3 Assembly; David N. Nelson, Librar-ians Assembly.
Deadlines: The deadline for the weekly update iseach Monday for the following week’s issue. Forthe March AT PENN calendar it is February 13.
See www.upenn.edu/almanac/calendar/caldead.html for details on event submission.
•To place a classified ad, call (215) 898-5274.
CLASSIFIEDS—UNIVERSITY
Almanac is not responsible for contents of classified ad material.
RESEARCH
UpdateJANUARY AT PENN
Shoulder Study: Do you have shoulder pain ortendonitis? You may qualify for free therapy. Weare studying the effectiveness of a new,scientifically based shoulder exercise program.Testing and treatment are free and will beperformed by a physical therapist experiencedwith managing shoulder problems. Call JasonBialker, MPT, at Penn Therapy and Fitness toarrange an appointment for initial testing to seeif you qualify (215) 614-0680.
The University of Pennsylvania Health Systemseeks volunteers for an osteoporosis medicalresearch study. If you meet the followingdescription, you may be eligible to participate:A postmenopausal woman 60 years or olderof normal weight who is not taking estrogenreplacement. Volunteers will receive a magneticresonance imaging (MRI) exam-which producesimages of the heel and spine, as well as a dualenergy X-ray absorptiometry (DEXA) scan,which uses a small amount of radiation todetermine bone density. Both exams—performedon the same day—take approximately 2 hours intotal. Participants receive $60. Please contactLouise Loh (215) 898-5664.
01/15/01 12:53 PM 200 S. 34th St. Subject arrested for disorderly conduct01/16/01 8:03 PM 3900 blk Chestnut St. Subject stopped for invesigation/w. on warrant/Arrest01/17/01 3:40 PM 3910 Irving St. Unwanted phone calls received01/17/01 8:56 PM 3710 Sansom St. Counterfeit travelers check used01/19/01 2:47 AM 3914 Spruce St. Complainant assaulted by 4 unknown males01/19/01 7:52 AM 255 S. 38th St. Unauthorized charges on credit card01/19/01 8:14 AM 423 Guardian Dr. Money taken from locked office01/19/01 10:33 AM 3400 Chestnut St. Unauthorized charges on credit card
01/16/01 5:09 AM 4600 Chestnut St. Robbery01/16/01 6:34 PM 5140 Cedar Av. Aggravated Assault01/16/01 9:43 PM 4643 Pine St. Aggravated Assault01/18/01 9:20 AM 4000 Walnut St. Aggravated Assault01/19/01 12:00 PM 101 52nd St. Robbery01/19/01 12:59 PM 106 38th St. Robbery01/20/01 10:44 PM 242 49th St. Aggravated Assault01/21/01 1:55 AM 5100 Sansom St. Robbery
TALKS30 Have you eaten? Have you jumped into thesea? Have you divorced?—Marriage, Divorce andCompeting Conceptions of Freedom in the PeoplesRepublic of China; William Alford, HarvardUniversity; 4:30 p.m.; 543 Williams Hall (Center
HOUSE FOR SALEOpen Sunday February 4, 1-3 p.m. Grad Hos-pital rehab — 1938 Pemberton. Gorgeous 2 BR,1 1/2 BA on best block! All brand new! Deckedyard. $175,000. (215) 848-7127.
Almanac is not responsible for contents of classified ad material.
•To place a classified ad, call (215) 898-5274.
CLASSIFIEDS—PERSONAL
All Aboard Express Almanac Want to be apprised of late-breaking news and time-sensitiveinformation that is published only on Almanac’s website? We will inform you as soon as we postsuch items if you are on board Express Almanac. A free electronic service, Express Almanac is sentwhenever we add something significant to our website: Between Issues news, the latest issue or theAT PENN calendar.
To register, send an e-mail message with “subscribe” as the Subject to [email protected] include your name, e-mail address, and mailing address. —Ed.
Dance Celebration, presented byDance Affiliates and Penn Presents,unveils the latest work byMummenschanz, a Swiss mimetroupe that displays figures that canbe broken down and built up again.Next, the latest evolution of thewordless theatrical form that wasinvented by the originalMummenschanz trio in 1972 comesto the Zellerbach Theatre at theAnnenberg Center—for six showsbeginning February 2 and runningthrough February 4.(See February AT PENN).
Mummenschanz transcends the barriers oflanguage, nationality and age attractingaudiences from 7-97 to achieve an art formthat remains universal in its appeal. It com-bines both organic and geometric elements. Theyblend three genres: dance, theater and puppetry.Discount Rush tickets are available at theAnnenberg Center Box Office for Pennfaculty/staff ($15) and students ($10).A PENNCard is required for these discounts.For more information call (215) 898-3900or visit www.PENNpresents.org.
Mummenschanz: Mixing Form with Function
for East Asian Studies).31 T Cell Production in HIV-1 Disease; JosephM. McCune, The Gladstone Institute of Virology,San Francisco; 4 p.m.; The Wistar Institute Audi-torium (Cancer Training Program).
The University has recently mailed over28,000 Calendar Year (CY) 2000 W-2 Forms toour employees’ home addresses as they appearon the Payroll File (Employee Database).
An explanation of the contents of the vari-ous boxes on the W-2 form is as follows:
A. Wages, tips, other compensation: thisrepresents the total amount of Federal Taxablecompensation paid or imputed to you duringCalendar Year 2000 through the University Pay-roll System. This amount includes:
a. The value of your taxable graduate and/orprofessional tuition benefits, if you, yourspouse and/or your dependent children havereceived such benefits;
b. The value of Group Life Insurance coveragefor amounts greater than $50,000. The pre-mium payments for this excess coverage, ifany, have been included as imputed income(see Excess Insurance Premium - below);
Amounts which are excluded from thisamount are:
c. Tax deferred annuity contributions (i.e.,TIAA/CREF);
d. Health, Dental and Vision Care insurancepremiums that have been sheltered;
e. Amounts voluntarily contributed to a de-pendent care or a medical reimbursementaccount. Also included this year are feesfor Parking, Transit Checks, TransPassand the Van Pool.
B. Federal income tax withheld: this rep-resents the amount of Federal Income tax whichwas withheld from your earnings during the yearand paid to the Internal Revenue Service, onyour behalf, by the University.
C. Dependent care benefits: this representsthe total amount which you have voluntarily“sheltered” for dependent care expenses, regard-less of whether you have been reimbursed bythe University for the expenses associated withthis “shelter” as of December 31, 2000.
D. Social security wages: this representsthe total amount of compensation paid to youduring Calendar Year 2000 which was subjectto Social Security (FICA/OASDI) tax, includ-ing all of your tax deferred annuity contribu-tions and excess life insurance premiums, if ap-plicable, but excluding health and dental insur-ance premiums and any voluntary dependentcare or medical reimbursement account contri-butions which you have “sheltered”.
E. Social security tax withheld: this repre-sents the total amount of Social Security (FICA/OASDI) tax which was withheld from yourearnings during the year and paid to the SocialSecurity Administration, on your behalf, by theUniversity.
F. Benefits included in box 1: if you havereceived certain fringe benefits, the value of suchbenefits is shown here, and is also included inBox 1, Wages, tips, other compensation. Thesebenefits include the value of taxable graduateand/or professional tuition benefits and otherbenefits relating to imputed income. If you havereceived any of these benefits the University hasrecently advised you, individually and person-ally, concerning their taxability; please refer tothose communications specifically.
G. Medicare wages and tips: this representsthe total amount of compensation paid to youduring Calendar Year 2000 which was subjectto Medicare tax, including all of your tax de-ferred annuity contributions and excess life in-surance premiums, if applicable, but excludinghealth and dental insurance premiums and any vol-untary dependent care or medical reimbursementaccount contributions which you have “sheltered”.
H. Medicare tax withheld: this representsthe total amount of Medicare tax which waswithheld from your earnings during the year andpaid to the Social Security Administration, onyour behalf, by the University.
I. Excess insurance premium: the Inter-nal Revenue Service requires that the premiumspaid by an employer for group life insurancecoverage in excess of $50,000 be imputed asincome to the employee. The amount whichappears in Box 13 and labeled (C) is the valueof the premiums paid for this excess insurancecoverage. This amount is based on an InternalRevenue Service (IRS) table which identifiespremiums for different age groups.
J. Tax deferred annuity contributions: thisrepresents the total amount of contributionsmade by an employee to a retirement plan on atax-deferred basis. The amount is shown in Box13 and labeled (E).
K. Excludable moving expense reimburse-ments: this represents the nontaxable moving ex-penditures that were paid to you as a reimburse-ment. The amount is shown in Box 13 and labeled(P). If any reimbursements or third party paymentswere deemed to be taxable income you were no-tified of these amounts under separate cover.
L. Employee’s social security number: thisis the number that the Federal and State Gov-ernments use to identify you with the tax returnsthat you file, so please review it for accuracy. Ifthe number is incorrect, then the University Pay-roll system is also inaccurate and you shouldcontact the Payroll Office, immediately, beforeyou file your returns.
M. State wages, tips, etc.: this representsthe total amount of compensation paid to youduring Calendar Year 2000 which was subject
to Pennsylvania State Income Tax, including allof your deferred annuity contributions, if appli-cable, but excluding health and dental insurancepremiums and any voluntary medical reimburse-ment account contributions which you have“sheltered”.
N. State income tax: this represents the to-tal amount of Pennsylvania State Income Taxwithheld during Calendar Year 2000 and paidto the Commonwealth of Pennsylvania, on yourbehalf, by the University. If you do not live in Penn-sylvania no amount will be reflected in this box.
If you lived a portion of the year in the Com-monwealth of Pennsylvania, and another por-tion in New Jersey or Delaware, you will re-ceive two W-2 forms, one showing the statetaxes paid to the Commonwealth of Pennsylva-nia, the other showing no taxes paid to the otherjurisdiction.
O. Local wages, tips, etc.: this representsthe total amount of compensation paid to youduring Calendar Year 2000 which was subjectto Philadelphia City Wage Tax, including all ofyour deferred annuity contributions.
P. Local income tax: this represents the to-tal amount of Philadelphia City Wage Tax with-held from your earnings during Calendar Year2000 and paid to the City of Philadelphia, onyour behalf, by the University.
When you receive your W-2 form, please re-view it immediately to ensure that your name isspelled correctly and that your Social Securitynumber is correct. If you feel that any informa-tion on your W-2 is incorrect, review your cal-culations carefully and compare the informationon the form with your final 2000 pay stub.
If you have availed yourself of certain tax-able benefits please review any additional in-formation which was provided to you, underseparate cover, concerning these benefits andtheir impact on your tax status. If you still be-lieve that your W-2 is in error, please contactthe W-2 Office at (215) 573-3277 or write to W-2 Office, Room 310, Franklin Building /6284.
You should have received, via the U.S. PostalService, your Federal and State Income TaxForms and related instructions for filing. Fed-eral Tax forms are available at the Internal Rev-enue Service, 600 Arch Street, Philadelphia, orby calling (800) TAX-FORM. Pennsylvania In-come Tax forms are available at the State Of-fice Building, 1400 Spring Garden Street, Phila-delphia, or by calling (888) PA-TAXES. Fed-eral and State forms are also available at manylibraries and U.S. Post offices.
—Theresa V. Lafferty,Manager, Payroll Department
The W-2Form forCalendar
Year 2000
PAYROLL DEPARTMENT
1/30/01
Whenever there is more than meets the eye, see our web site,www.upenn.edu/almanac/.
FebruaryA T P E N N
FILMS5 HBO Nights; Sex and the City, So-pranos; 5-7 p.m.; Bistro, Houston Hall.Also February 12, 19 & 26 (Office ofStudent Life).7 Head Over Heels (2001); 9 p.m.;Hall of Flags, Houston Hall. Free passes at200 Houston Hall (Office of Student Life).9 Woman Human Demon; 8 p.m.; In-ternational House; discussion with directorHuang Shuqin to follow (Center for EastAsian Studies; International House).21 African Film Festival; InternationalHouse; call (215) 895-6569 for showtimes. Through February 24.Margaret Mead Filmand Video FestivalHarrison Auditorium, UniversityMuseum. Evenings: $6, $3/students,senior citizens, PENNCard holders.Saturday and Sunday afternoonscreenings free with admission.23 The Laughing Club of India(1999), India Cabaret (1985); 7:30 p.m.24 The Great Mojado Invasion(1999), On and Off the Res’ w/CharlieHill (2000), Seven Hours to Burn(1999); 2 p.m.
Liebe Perla (1999), Stairway toHeaven (1998); 7:30 p.m.25 Santo Forte (2000), You Can’t Livewith Your Mouth Shut (1999); 2 p.m.
Zinat, A Special Day (2000), TheChild the Stork Brought Home (2000);7:30 p.m.
Department of Slavic Languages5:30 p.m.; TV Lounge, ModernLanguages Program at Gregory House6 Oblomov (1980); Russian w/subtitles.20 An Unfinished Plan for a Mechani-cal Piano (1977); Russian with subtitles.
MEETINGS15 A-3 General Assembly; single par-ent support group; noon-1:30 p.m.; loca-tion TBA. Info.: (215) 898-1788.16 Trustees Stated Meeting; 1:45-2:45 p.m.; Inn at Penn.21 University Council; 4-6 p.m.;Bodek Lounge, Houston Hall. Info.:(215) 898-7005.
MUSIC2 Penn Flutes; 5 p.m.; Bookstore(Bookstore).14 Glee Club; 5 p.m.; free. HoustonHall Bistro (Penn Performing Arts).18 Amherst Early Music Faculty Con-cert; 8 p.m.; Amado Recital Hall, IrvineAuditorium (Music).25 Boys Choir of Harlem; 3 p.m.;Zellerbach Theatre, Annenberg Center;$20, $25, $30. Info./tickets: (215) 898-3900 or www.PennPresents.org. Seephoto, reverse (Penn Presents).
International Music SeriesAll shows at the International House.Tickets: (215) 569-9700.3 Marlon Simon and the NagualSpirits; Latin jazz; 8 p.m.; $15.17 Ban Rra Rra; Cuban music anddance; 8 p.m.; $25.
ON STAGE2 MotherSON; one-man play; Jewishmother struggles to understand gay son;8 p.m.; Iron Gate Theater; $20; free/stu-dents. Info.: (215) 898-3900. Also Feb-ruary 3 (Phila. PFLAG; Beth Ahavah).
All’s Fair in Love and Dwarves;Mask & Wig’s 113th production; 7 p.m.,doors; 8 p.m., show; Mask & Wig Club-house, 310 Quince St. Info./tickets: (215)923-4229. Through March 24.8 Li’l Abner; Penn Law School LightOpera Company; 8 p.m.; Zellerbach Theatre,Annenberg Center. $8; $5/Penn ID Info./tick-ets: (215) 898-6791. Also February 9 & 10.
Student Performing ArtsAll shows, 5 p.m.; free. Houston Hall Bistro.
7 Without A Net21 Yofi!28 Onda Latina
Penn PresentsInfo./tickets: (215) 898-3900 orwww.PennPresents.org.2 Mummenschanz; Swiss mime; 8 p.m.;Zellerbach Theatre, Annenberg Center; $35,$30, $25; matinee: $30, $25, $20. Also Feb-ruary 3, 2 & 8 p.m. and February 4, 3 p.m.15 River North Chicago Dance; fusionof ballet, modern and jazz dance; 7:30p.m.; Zellerbach Theatre, Annenberg Cen-ter; $33, $31, $29; matinee tickets: $30,$28, $26. Also February 16, 8 p.m. andFebruary 17, 2 & 8 p.m.
SPECIAL EVENTS3 Nursing Graduate Education Day;overview of programs; opportunity tospeak with directors; 8:30 a.m.-2 p.m.;lobby, Nursing Education Bldg. (Nurs-ing Graduate Enrollment Management).4 Tu B’Shevat Celebration; JewishNew Year of Trees; crafts, games andpuppet show; 2-4 p.m.; Widener VisitorCenter, Morris Arboretum; free w/ad-mission. Registration: (215) 247-5777,ext. 125 (Arboretum).7 Wednesdays with Morrie; free vanride to the Philadelphia Museum of Art forweekly events. PENNCard required. Seewww.upenn.edu/resliv/chas/programs/van.html for route; 5-9 p.m. Info.: (215)898-5551. Also February 14, 21 &28.10 Skate ‘Till Your Heart’s Content;Valentine’s family skating package for 2adults and 2 children; 12:30-4 p.m.;Class of 1923 Ice Rink; $5/family(Sansom Common; Classof 1923 IceRink).
14 ENIAC 55 Year Celebration; pre-miere of film Mauchly: The Computerand the Skateboard; 4:30-6:30 p.m.;Heilmeier Hall, Towne Bldg. (SEAS).
Valentine’s Day Dinner; limited a lacarte menu: Chateaubriand for two; 5-8p.m.; Faculty Club, Inn at Penn; $23.95/person. Reservations: (215) 898-4618.15 Go West, 3rd Thursdays: MeetOver a Different Menu; 2-for-1 dinnerspecials; see www.UCityphila.com or1-888-GOWEST-7 for participatingrestaurants. See reverse (UCD).17 12th Annual Celebration of AfricanCultures; dance, storytelling, music andart; 11 a.m.-4 p.m. featured: Women’sSekere Ensemble, group of female percus-sionists of Nigeria, noon & 2 p.m.; AfricanRhythms Drum and Dance Troupe, 11:30a.m.; African-American Stilt Ballet, youngdancers from the Philadelphia area, 1 p.m.;Images of the Motherland, interactive pro-gram, 1:30 p.m.; Ballet Shango AfricanDance Theatre, dancers and drummers of-fer West African dance workshop, 12:30p.m., and finale performance, 3:15 p.m.The Philadelphia Zoo’s "Zoo on Wheels"1 to 3 p.m.; University Museum; free w/admission (Museum).22 2001 Equal Justice Foundation Auc-tion; funds will support Penn Law studentsin public service careers; 6 p.m.; rm. 100,Law School (Law School Sesquicentennial).25 Christian Association Open House;CA celebrates its new building and hon-ors Philadelphia artist Sam Maitin; in-cludes a panel on Social TransformationThrough the Arts; 5-7 p.m.; 118 S. 37th St.
SPORTSTickets for basketball games: $18/sidecourt & lower end court; $12/upper endcourt; $6/seniors, children & PENNCardholders. Info/tickets: (215) 898-6151 orwww.pennathletics.com.2 (M) Basketball vs. Yale; 7 p.m.3 Wrestling vs. Harvard; 2 p.m.
(M) Basketball vs. Brown; 7 p.m.4 Wrestling vs. Brown & GeorgeMason; 1 p.m.9 (W) Basketball vs. Harvard; 7 p.m.
Gymnastics vs. Temple; 7 p.m.10 (W) Squash vs. Harvard; 11:30 a.m.
(M) Squash vs. Harvard; 2 p.m.(W) Basketball vs. Dartmouth; 7 p.m.
11 (W) Fencing vs. Temple; 10 a.m.(W) Squash vs. Dartmouth; 11:30 a.m.Gymnastics vs. Ursinus; 1 p.m.(M) Squash vs. Dartmouth; 1:30 p.m.(M/W) Fencing vs. Princeton; 2 p.m.
13 (M) Basketball vs. Princeton; 7 p.m.14 Wrestling vs. Princeton; 7 p.m.16 (W) Basketball vs. Cornell; 7 p.m.17 (M) Swimming vs. Harvard; 1 p.m.
(W) Basketball vs. Columbia; 7 p.m.23 (M) Basketball vs. Dartmouth; 7 p.m.24 (M) Basketball vs. Harvard; 7 p.m.
Margaret MeadFilm FestivalFebruary 23 through 25Counter clockwise,from upper right:• On and Off the Res’
w/Charlie Hill• Seven Hours to Burn• Stairway to Heaven• The Laughing Club
of India
See Films, below.
ACADEMIC CALENDAR16 Drop Period Ends.
CHILDREN’S ACTIVITIES6 Story Hour; 11 a.m.; Bookstore.Also February 13, 20 (10 a.m.) and 27.
CONFERENCE2 HIV/AIDS in Africa: The CriticalLink Between Human Rights and Health;8:30 a.m.-5 p.m.; Bodek Lounge, Hous-ton Hall. Registration required: (215)823-4206 or [email protected](African Studies Center).
EXHIBITSAdmission donations and hours
Arthur Ross Gallery, Fisher FineArts Library: free, Tues.-Fri., 10 a.m.-5p.m., Sat. & Sun., noon-5 p.m.
Morris Arboretum: $6, $5/seniors,$4/students, free with PENNCard, chil-dren under 6; Mon.-Fri., 10 a.m.-4 p.m.;Sat. & Sun., 10 a.m.-5 p.m.
University Museum: $5, $2.50/se-niors and students w/ID, free/members,with PENNCard, children under 6;Tues.-Sat., 10 a.m.-4:30 p.m., Sunday(free), 1-5 p.m.
Upcoming2 Paintings of William J. Bank, M.D.;assistant professor of neurology at theSchool of Medicine, self-taught artist.Opening reception: February 2, 4:30-6:30 p.m.; Burrison Art Gallery.Through February 28.
Kate Egan & Deirdre Murphy;GSFA. Opening reception: February 8,5-7:30 p.m., with poetry reading by CortDay. Kelly Writers House. ThroughFebruary 28.3 Jon Schueler: About the Sky; aretrospective; oil paintings by this ab-stract expressionist who was a pilot inWorld War II and later spent much ofhis time living in Scotland; a member ofthe postwar California School, he origi-nally exhibited with Rothko and Avery;Arthur Ross Gallery. Through April 15(Sweet Briar College Alumnae Club).15 KAHN at 100: A Memorial Exhibi-tion; selection of master drawings, mod-els, sketchbooks, manuscripts and memo-rabilia by world-renowned Philadelphiaarchitect Louis I. Kahn; Kroiz Gallery.Through September 15. See Talks.19 Tokyo Tales; Klein-Dytham Architec-ture, Tokyo, Japan; Meyerson Gallery.Through February 24. See Talks, reverse.
Large Print and Digital Works on Paper;traditional and digital prints by faculty,staff and graduate and undergraduatestudents from printmaking and digital finearts departments. Opening reception: Febru-ary 23, 5-7 p.m.; lower gallery, MeyersonHall. In conjunction with Penn Printmakingand Digital Symposia. Through March 4.See Fitness/Learning, reverse.
Nicholas Coviello; professor, digitalfine arts. Opening reception: February 23,5-7 p.m.; Dean’s Alley, Meyerson Hall. Inconjunction with Penn Printmaking andDigital Symposia. Through March 4.See Fitness/Learning, reverse.24 Bruce Yonemoto; Los Angelesartist’s first one-person Americanmuseum show; featuring video installa-tion for the InterCommunciation Centerin Tokyo; a large, three-channel work,Hanabi Fireworks—blurred imagesof recognizable corporate logos floatlike apparitions on multiple screensand morph into pyrotechnics.Opening reception: February 23, 6-8 p.m.; ICA. Through April 22.
Clint Takeda; Philadelphiaartist; sculptures, drawings, andpaintings of imaginary creaturesin a Surrealist style. On site,Takeda will create three large,life-size figures: a monkey, amonk, and a scientist.Worksrelate to images and ideas ofsensory deprivation andevolution from pop cul-ture and science fictionfilms. Opening recep-tion: February 23, 6-8p.m.; ICA. Through April 22.
NowLisa Yuskavage; Philadelphia
artist’s unsettling and provocativepaintings; ICA. Through February 4.
Hella Jongerius and Jurgen Bey;Dutch designers’ “Droog” productsmade from recycled mass-producedobjects; ICA. Through February 4.
Mei Ling Hom: Silkworm Grind;installation focusing on Asian women’sexperiences; ICA. Through February 4.
Theodore Dreiser’s Sister Carrie; 6thfl., Rosenwald Gallery, Van Pelt-DietrichLibrary Center. Through February 5.
MFA First Year Exhibition; Upperand Lower Galleries, Meyerson Hall.Through February 11.
Pomo Indian Basket Weavers:Their Baskets and the Art Market; text,video and photos of 120 turn-of-the-century Native American baskets; 2ndfl., Dietrich Gallery, University Museum.Through February 25.
The Diving Board Series; encausticpaintings on panels by EleanorSchimmel; Esther M. Klein Gallery.Through March 3.
OngoingAncient Greek World; Canaan and
Ancient Israel; Living in Balance: Uni-verse of the Hopi, Zuni, Navajo andApache; Ancient Mesopotamia: RoyalTombs of Ur; The Egyptian Mummy: Se-crets and Science; Raven’s Journey:World of Alaska’s Native People; Bud-dhism: History and Diversity of a GreatTradition; University Museum.
Healing Plants: Medicine AcrossTime and Cultures; Morris Arboretum.
University Museum ToursMeet at the main entrance; 1:30 p.m.Free with Museum admission donation.Info.: www.upenn.edu/museum/.3 Mesoamerica4 Archaeology10 Raven’s Journey11 Ancient Egypt18 American Southwest24 Highlights of the Collection25 China
Suite 211 Nichols House, 3600 Chestnut St. Philadelphia, PA 19104-6106
Unless otherwise noted all events are opento the general public as well as to members ofthe University. For building locations, call(215) 898-5000 between 9 a.m. and 5 p.m.Listing of a phone number normally meanstickets, reservations or registration required.
This February calendar is a pull-out forposting. Almanac carries an Update withadditions, changes and cancellations if re-ceived by Monday noon prior to the week ofpublication. Members of the University maysend notices for the Update or March ATPENN calendar. Deadlines can be found on-line at www.upenn.edu/almanac/calendar/caldead.html.
of River North Chicago Dance will leaveaudiences breathless, February 15-17.The group, comprised of 13 highly-trained, dynamic professionals, is noted
for its varied, eclectic repertoireset to some of the century’s
greatest, mostrecognizable
music.See On
Stage.
FebruaryA T P E N N
1/30/01
1 Moral and Ethical Dilemmas in theSpecial-Care Nursery; Arthur Caplan,Center for Bioethics; noon-1:30 p.m.;suite 320, 3401 Market St. (Center forBioethics).
Current Issues Effecting MarineMammal Conservation; Laela Sayigh,University of North Carolina atWilmington; 12:15-1:45 p.m.; GrossmanAuditorium, Wistar Institute (Institutefor Environmental Studies [IES]).
Wilkomirski/Wiesel: Problems ofMemory and Factuality in Recent Holo-caust Memoirs; Susan Rubin Suleiman,Harvard; 4:30 p.m.; Cherpack Lounge,Williams Hall (French Institute).
Recent Work; Claudine Lorenz andFlorian Musso, Atelier d’ArchitectureClaudine Lorenz Florian Musso; 6 p.m.;B-3, Meyerson Hall (Architecture;GSFA).2 Disease Diagnosis, Surveillanceand Prevention in the Rodent Lab; LauraDavis, SmithKline Beecham Pharmaceu-ticals; 10 a.m.-noon; Medical AlumniHall, HUP (University Veterinarian).5 Troponin T Isoforms and HeartFailure; Jian-Ping Jin, Case WesternReserve University; 2 p.m.; WoodRoom, 2nd fl., John Morgan Bldg.(Pennsylvania Muscle Institute).
A New Computational Tool for the Sci-ence and Engineering of Complex Fluids;Venkat Ganesan, University of Califor-nia—Santa Barbara; 3:30 p.m.; rm. 337,Towne Bldg. (Chemical Engineering).
Intra Nuclear Position of VirusEpisome or Plasmid Vector AffectsTranscription and Replication: Cell Bi-ology of Position Control; Gerd Maul,Wistar Institute; 4-5 p.m.; Austrian Au-ditorium, CRB (Institute For HumanGene Therapy [IHGT]).
Recent Work; Odile Decq, Decq +Cornette Architects, Paris; 6 p.m.; B-1,Meyerson Hall (Architecture; Ewing,Cole and Associates; GSFA).6 Special Panel on Water Manage-ment; Walter Lyon, systems engineering;Susan Lior, Philadelphia Water Commis-sion; Carol Collier, Delaware River BasinCommission; Robert Traver, VillanovaUniversity; 6- 9 p.m.; rm. 337, TowneBldg. (IES; Systems Engineering).7 Role of Cadherins in Animal Mor-phogenesis; Ulrich Tepass, University of
Toronto; noon; rm. 251, BRB II/III(Center for Research on Reproduction&Women’s Health [CRRWH]).
Functional Materials and Devicesvia Templated Colloidal Assembly; OrlinVelev, University of Delaware; 3 p.m.; rm.337, Towne Bldg. (Chemical Engineering).
Immunotherapy of Cancer withLive Bacterial Vectors and Their Prod-ucts; Yvonne Paterson, microbiology; 4p.m.; Grossman Auditorium, Wistar In-stitute (Wistar Institute).
Covering the World from CapeTown to Moscow: How a ForeignCorrespondent Figures Out Where theWorld is Headed; Trudy Rubin,Philadelphia Inquirer; 5 p.m.; rm. 402,Logan Hall (International Relations).
Contemporary Processes in Archi-tecture; Panel discussion/colloquium,Ali Rahim, architecture; respondents:Ben van Berkel, Van Berkel & Bos Ar-chitectural Bureau, Amsterdam; WilliamBraham, architecture; Michael Speaks,Sci-Arc; 6 p.m.; Upper Gallery,Meyerson Hall (Architecture; GSFA).8 Active Transport from Prague1960 to Los Angeles 2000; ErnestWright, University of California—LosAngeles; 4 p.m.; Class of ‘62 LectureHall, John Morgan Bldg. (Physiology).
The Religious Professional: WhatRole Should Religious Commitment Playin the Work of Lawyers and Doctors?Martha Minow, Harvard Law School;4 p.m.; rm. 240-A, Law School (LawSchool Sesquicentennial).
Bidding for the Olympics 2012:Designs, Plans and Politics; AlexanderGarvin, Yale University and PlanningCommission of New York City; 6 p.m.;B-1, Meyerson Hall (City & RegionalPlanning; GSFA).
Class and Christian Diversity;Maureen Tilley, University of Dayton; 7p.m.; 2nd fl. lounge, Logan Hall (Phila-delphia Seminar on Christian Origins).9 Rabbits: Biology, Care, Handling,Identification, Nomenclature, Breedingand Genetics; Norman Lefebvre, HazeltonResearch Products; 10 a.m.-noon; MedicalAlumni Hall, HUP (University Veterinarian).
Economic Issues in ComparingAntidepressant Drug Therapy, Psycho-therapy, and their Combination for theTreatment of Acute Phase ChronicDepression; Ernst Berndt, MIT—Sloan;
noon-1:30 p.m.; 1st fl. auditorium,Colonial Penn Center (Leonard DavisInstitute [LDI]).
Evolution of Language: fromAnimal Communication to UniversalGrammar; Martin Nowak, head,Program in Theoretical Biology, Institutefor Advanced Study; noon; rm. G-17,Logan Hall (Institute for Research inCognitive Science [IRCS]).
Structural Changes that DriveMyosin Molecules along Actin Fila-ments; Peter Knight, Leeds University,U.K.; 2 p.m.; rm. 251, BRB II/III(Pennsylvania Muscle Institute).12 The Importance of the HeyueYingling Ji for the History of HighTang Poetry; Paul Kroll, University ofColorado; noon; 543 Williams Hall(Center for East Asian Studies).
Random Walks and FeedbackLoops in Autocrine Cell Signaling;Stanislav Shvartsman, MassachussettsInstitute of Technology; 3:30 p.m.; rm.337, Towne (Chemical Engineering).
Fetal Gene Therapy: CurrentStatus and Future Potential; Alan W.Flake, CHOP; 4-5 p.m.; AustrianAuditorium, CRB (IHGT).
Geometry and Topology ofGroups; Dusa McDuff, SUNY—StonyBrook; four-day lecture series; 4 p.m.;A-6, DRL. Also February 13-15(Mathematics).
Urban Flotsam: Stirring the Skinof the Earth; Raoul Bunschoten Chora,Institute of Urbanism and the Architec-tural Association, London; 6 p.m.; B-level,Meyerson Hall (Landscape Architecture;GSFA).14 Conditional Gene Targeting inMice: Uncovering New Functions forFoxa2 (HNF3b); Klaus Kaestner,genetics; noon; rm. 251, BRB II/III(CRRWH).
Discussion on Hans Jonas’ Essay“Philosophical Reflections on Experi-menting with Human Subjects”; RenéeFox, Center for Bioethics; noon-1:30p.m.; rm. 320, 3401 Market St. (Centerfor Bioethics).
Engineering Antibody Therapeu-tics: Applications to Bacterial Toxins;Jennifer Maynard, University ofTexas—Austin; 3:30 p.m.; rm. 337,Towne Bldg. (Chemical Engineering).
BRCA1 and DNA Repair; Wen-
Hwa Lee, University of Texas—San An-tonio; 4 p.m.; Grossman Auditorium,Wistar Institute (Wistar Institute).
Styles of Love Poetry; EdwardHirsch, poet, reads from Hirsch’s bookOn Love; lecture by religious studiesprofessor Ann Matter on St. Valentine;5-6:30 p.m.; Kelly Writers House (PennHumanities Forum; Writers House).
The Louis I. Kahn Memorial Lec-ture; Tadao Ando, Osaka, Japan; 6:30p.m.; University Museum. Info.: www.foundationforarchitecture.org. See Exhib-its (Foundation for Architecture; GSFA).15 Texte et Musique au Moyen Age:Desir Narcissique ey Voix Femininedans le Motet 7 de Guillaume deMachaut; Kevin Brownlee, RomanceLanguages; noon; Class of 1947 MeetingRoom, Houston Hall (French Institute).
TBA; Ray Fabius, InteliHealth.com;noon-1:30 p.m.; 1st fl. auditorium,Colonial Penn Center (LDI).19 Expanding the Influence of anAlready Powerful Cell-EnhancingDendritic Cell Function ThroughGenetic Modification; Ronald Crystal,Cornell University; 4-5 p.m.; AustrianAuditorium, CRB (IHGT).
New Uses of Old Buildings: Method-ologies for Compatible Designs; GabriellaCaterina, University of Naples; 6 p.m.; B-level, Meyerson Hall (Graduate Programin Historic Preservation; GSFA).20 Cross Talk Between Two Compo-nent Signaling System; Mark Goulian,physics & astronomy; noon; 2nd fl. con-ference room, Vagelos Research Labs(Institute for Medicine & Engineering).
Will Lowering PharmaceuticalPrices Jeopardize Breakthrough Re-search? The Moral Crusades; DonaldLight, Center for Bioethics; noon-1:30p.m.; rm. 320, 3401 Market St. (Centerfor Bioethics).21 Biological and Molecular Basis ofBreast Cancer Prevention; Jose Russo,
Fox Chase Cancer Center; noon; rm.251, BRB II/III (CRRWH).
Institute for Law and EconomicsLaw and Entrepreneurship Lecture—Private Equity: Difficult Investing in aDifficult Time; Paul Levy, L’72; 4:30p.m.; rm. 245-A, Law School (LawSchool Sesquicentennial).
Philadelphia Self-Taught Art; JohnOllman, Fleisher-Ollman Gallery, on thehistory of self-taught art in Philadelphia;5-6:30 p.m.; 1st floor, 3619 LocustWalk. Registration required: (215) 573-8280 (Penn Humanities Forum).22 Tokyo Tales; Mark Dytham, KleinDytham Architecture, Tokyo, Japan;6 p.m.; B-3, Meyerson Hall. SeeExhibits (Architecture; GSFA).23 Occupational Health in Labora-tory Animal Medicine; Christian New-comer, University of North CarolinaSchool of Medicine; 10 a.m.-noon;Medical Alumni Hall, HUP (UniversityVeterinarian).26 Block Copolymer Micelles inWater; You-Yeon Won, MassachussettsInstitute of Technology; 3:30 p.m.; rm.337, Towne Bldg. (Chemical Engineering).
Gene and Immunotherapy forCancer: Making the Tumor a BetterPlace to Die; Richard G. Vile, MayoClinic; 4-5 p.m.; Austrian Auditorium,CRB (IHGT).
Planning for a New Century: TheBig Issues; panel discussion and booksigning; Jonathan Barnett, city & regionalplanning; 6 p.m.; B-3, Meyerson Hall(City & Regional Planning; GSFA).27 The Divine Image of India; AnnSloan, history of art; 1 p.m.; FacultyClub, Inn at Penn (Women’s Club).
Style and Meaning in Music; LeonBotstein, Bard College; 5-6:30 p.m.; rm.200, College Hall (Penn Humanities Fo-rum; Music; Germanic Languages &Literatures).28 Translational Delay in MammalianGerm Cells; Robert Braun, University ofWashington; noon; rm. 251, BRB II/III(CRRWH).
Structural Insights into Recognitionand Regulation in Tyrosine Kinase Signal-ing; Michael Eck, Dana-Farber CancerInstitute; 4 p.m.; Grossman Auditorium,Wistar Institute (Wistar Institute).
TALKS TALKS TALKS TALKS TALKS
14 PPSA Book Discussion Group; PatCroce’s I Feel Great and You Will Too!;12:15-1:15 p.m.; Bookstore (PPSA).
Penn Bookstore1 The Doctor Makes a DollhouseCall; author Robin Hathaway; noon.7 Animal Patients: 50 Years in theLife of an Animal Doctor; EdwardScanlon, alumnus; noon.8 The Moral Stake in Education:Contested Premises and Practices; sign-ing and lecture by Joan Goodman, edu-cation, Howard Lesnick, law; noon.
Finding Fish: a Memoir; AntwoneFisher, screenwriter; Black HistoryMonth; 2 p.m.9 On Her Own Ground: The Life andTimes of Madam C.J. Walker; A’LeliaBundles, journalist; Black HistoryMonth; noon.15 The Sound of Sleat, A Painter’s Life;readings by Magda Salvesen, widow ofartist Jon Schueler; 1 p.m. See Exhibits.16 A Force More Powerful: A Cen-tury of Non-Violent Conflict; authorsJack DuVall, Peter Ackerman; noon.
Kelly Writers House3805 Locust Walk. Info.: (215) 573-WRIT, [email protected] orwww.english.upenn.edu/~wh/.7 Speakeasy: Poetry, Prose & Any-thing Goes; open mic performance;8 p.m. Also February 21.12 Tony Kushner; readings byPulitzer-winning author of Angels inAmerica: A Gay Fantasia on NationalThemes; 7 p.m.14 Loved Poems and Poems aboutLove; group readings and discussion;3 p.m. Call or e-mail to RSVP.17 The Laughing Hermit ReadingSeries; poets Brenda McMillan, MollyRussakoff; 4 p.m.18 Live at the Writers House; aone-hour spoken-word and music radioshow; 11 p.m.
Jazzercise; 5:30-6:30 p.m.; Tues-day and Thursday; Newman Center; firstclass free; $4.50/class, $3.50/students;Carolyn Hamilton, (215) 662-3293(days) or (610) 446-1983 (evenings).
Class of 1923 Ice Rink Public Skat-ing Sessions; Mon. & Wed., 1:30-3 p.m.*;Tues., noon-1:30 p.m.*; Thurs., noon-1:30p.m.* & 7-9 p.m.; Fri., 8-10 p.m. & mid-night-2 a.m.; Sat., 12:30-2:30 p.m., 8-10 p.m.& midnight-2 a.m.; and Sun., 12:30-2:30p.m. Class of ‘23 Ice Rink, 3130 WalnutSt. Admission: $5.50; $4.50/PENNCard;(*indicates $1-off admission); skate rental:$1.50/per session (Class of ‘23 Ice Rink).1 Salsa Lessons; 5-7 p.m.; HoustonHall Bistro; free (Ballroom Dance).5 Strictly Speaking ToastmastersMeeting; 6:30 p.m.; Penn Bookstore.Also February 19 (Bookstore).15 Swing Lessons; 5-7 p.m.; HoustonHall Bistro; free (Ballroom Dance).20 Caring for Older Parents; SarahKagan, gerontologic nursing, Mary AnnForciea, geriatric medicine, Brian Duke,Regional Initiative in Geriatrics,Marilyn Kraut, Quality of Work Life;4-6 p.m.; auditorium, ARCH (AWFA).21 Etiquette in the Workplace; MaryMitchell, Mitchell & Associates; 12:15p.m.; Terrace Rm., Logan Hall (PPSA,A-3 General Assembly, Human Re-sources).22 Meet Me at the Living Room;informal networking with fellow Pennwomen; 5-6 p.m.; Living Room, Inn AtPenn (Association of Women Faculty &Administrators).
23 Penn Printmaking and DigitalSymposia; two workshops—Non-toxicPrintmaking With Digital EnhancedProcesses; Nick Coviello, instructor; 9a.m.-noon; and Experimental DigitalTechniques; Joshua Moseley, Fine Artsdigital professor and Brian Kreydatus,Fine Arts printmaking professor, instruc-tors; 1-4 p.m. Both workshops: printshop,basement, Morgan Bldg. Registration re-quired: (215) 898-8374 or murphy@pobox. upenn.edu. Opening reception:February 23, 5-7 p.m.; lower gallery,Meyerson Hall. See Exhibits, reverse.
ISC Technology Training GroupAll classes are held at Sansom PlaceWest/3650 Chestnut Street, 2nd floor.Registration required: (215) 573-3102.Info.: [email protected] orwww.upenn.edu/computing/isc/ttg.Hands-on Windows Courses1 Introduction to Access 20005 Intro. to Filemaker Pro 4.013 Introduction to Windows 200015 Intermediate Word 200019 Intermediate Excel 200021 Advanced PowerPoint 200027 Intermediate Access 2000Hands-on Macintosh Courses7 Advanced Word 9820 Creating a Web Page
Morris ArboretumCall (215) 247-5777, ext. 125 for regis-tration and additional information.
Office of Community HousingNoon-1 p.m. & 1-2 p.m.; 4046 WalnutSt. Info./RSVP: (215) 898-7422 [email protected] Community Housing 101. Also onFebruary 28. Held at rm. 720, FranklinBldg. on Februrary 14.7 Tax Planning.19 Homeowner’s Insurance.21 Credit Counseling and Repair.26 Home Inspection.
Quality of Worklife WorkshopsAll sessions: 11:30 a.m. -1 p.m; rm. 223,Golkin Room, Houston Hall. Registrationrequired: www.hr.upenn.edu/training_coursecatalog/search_ criteria.asp. Info.:(215) 898-5116 or [email protected] Summer Child Care Options; as-sess your child's interests, and exploreoptions for summer activities.21 Handling the Difficult and AngryCustomer; techniques for customer ser-vice approach to dealing with difficultand angry customers.
3rd Thursdays:February 15
Dine in a NewDirection!
Join friends, colleagues, andneighbors after work or afterclass at one of University City’sdelicious restaurants—andindulge in 2-for-1 entrees.*
To obtain the 3rd Thursdayspecial, ask your server for the3rd Thursday special discount.
Free metered parking after6 p.m. on 3rd Thursdays inUniversity City! Participating RestaurantsAcademic Bistro (BYOB)2 for 1 on entire $22 prix fixe.Culinary Academy,Drexel University33rd & Arch Sts.(215) 895-2992(reservations required)Pizza Rustica (pizzas only)3602 Chestnut St.(215) 895-34902 Goodfellas (Italian, BYOB)4101 Walnut Street(215) 382-3600Marigold Dining Room(American, BYOB)501 S. 45th St.(215) 222-3699Palladium Restaurant & Bar(American)3601 Locust Walk(215) 387-3463Shula's Steak 2 (American)3600 Chestnut St.(Sheraton University City)(215) 386-5556The Restaurant School(Italian, American)4207 Walnut Street(215) 222-4200Sitar India (Indian, BYOB,excludes buffet special)60 S. 38th St.(215) 662-0818* Excludes beverages, tax, and gratuityand may not be used with other promo-tions. Discount taken on entree of equal/lesser value.
For more information call1-888-GOWEST-7 or visitwww.universitycitydistrict.org/.
Let’s Hear It for the Boys!With the dual musical heritage of theEuropean boys choir and the African-American church choir, The BoysChoir of Harlem has an artistic
repertoire ranging from classicalmusic to jazz, contemporary songs,
gospels, spirituals and speciallycommissioned works by leadingAfrican-American composers.See Music, reverse.
